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Kai Stoeber

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TOP 3
Claire M Mulvey; Kai Stoeber; Slavica Tudzarova; Gareth H Williams; Mark Crawford; Jasminka Godovac-Zimmermann
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint.
John D Kelly; Hing Y Leung; Odu Okoturo; Robert S Pickard; A Toby Prevost; Teresa Prevost; Wendy Robson; Fiona Tulloch; Joana C Vasconcelos; Nikhil Vasdev; Gareth H Williams; Alex Wollenschlaeger; Keith Burling; Tim J Dudderidge; Ian Halsall; Kai Stoeber
Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.
Gareth H Williams; Kai Stoeber
The cell cycle and cancer.

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All Publications

2013: Claire M Mulvey; Kai Stoeber; Slavica Tudzarova; Gareth H Williams; Mark Crawford; Jasminka Godovac-Zimmermann
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint.
Journal of proteome research 2013;12(3):1436-53.
2012: John D Kelly; Hing Y Leung; Odu Okoturo; Robert S Pickard; A Toby Prevost; Teresa Prevost; Wendy Robson; Fiona Tulloch; Joana C Vasconcelos; Nikhil Vasdev; Gareth H Williams; Alex Wollenschlaeger; Keith Burling; Tim J Dudderidge; Ian Halsall; Kai Stoeber
Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.
PloS one 2012;7(7):e40305.
2012: Gareth H Williams; Kai Stoeber
The cell cycle and cancer.
The Journal of pathology 2012;226(2):352-64.
2011: Slavica Tudzarova; Sergio L Colombo; Kai Stoeber; Saul Carcamo; Gareth H Williams; Salvador Moncada
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(13):5278-83.
2010: Slavica Tudzarova; Matthew W B Trotter; Alex Wollenschlaeger; Claire Mulvey; Jasminka Godovac-Zimmermann; Gareth H Williams; Kai Stoeber
Molecular architecture of the DNA replication origin activation checkpoint.
The EMBO journal 2010;29(19):3381-94.
2010: Sara Rodriguez-Acebes; Ian Proctor; Marco Loddo; Alex Wollenschlaeger; Mohammed Rashid; Mary Falzon; A Toby Prevost; Richard Sainsbury; Kai Stoeber; Gareth H Williams
Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers.
The American journal of pathology 2010;177(4):2034-45.
2010: Claire Mulvey; Slavica Tudzarova; Mark Crawford; Gareth H Williams; Kai Stoeber; Jasminka Godovac-Zimmermann
Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint.
Journal of proteome research 2010;9(10):5445-60.
2010: T J Dudderidge; J D Kelly; A Wollenschlaeger; O Okoturo; T Prevost; W Robson; H Y Leung; G H Williams; Kai Stoeber
Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments.
British journal of cancer 2010;103(5):701-7.
2010: Ian Proctor; Kai Stoeber; Gareth H Williams
Biomarkers in bladder cancer.
Histopathology 2010;57(1):1-13.
2009: Anjana A Kulkarni; Sarah R Kingsbury; Slavica Tudzarova; Hye-Kyung Hong; Marco Loddo; Mohammed Rashid; Sara Rodriguez-Acebes; Andrew T Prevost; Jonathan A Ledermann; Kai Stoeber; Gareth H Williams
Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(7):2417-25.
2009: Marco Loddo; Sarah R Kingsbury; M Rashid; I Proctor; C Holt; Joanne Young; S El-Sheikh; M Falzon; Kathryn Leigh Eward; T Prevost; R Sainsbury; Kai Stoeber; Gareth H Williams
Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer.
British journal of cancer 2009;100(6):959-70.
2008: Sally Roberts; Sarah R Kingsbury; Kai Stoeber; Gillian L Knight; Phillip H Gallimore; Gareth H Williams
Identification of an arginine-rich motif in human papillomavirus type 1 E1;E4 protein necessary for E4-mediated inhibition of cellular DNA synthesis in vitro and in cells.
Journal of virology 2008;82(18):9056-64.
2008: Anne-Sophie Rebstock; Cristina Visintin; Elisabetta Leo; Cristina Garcia Posada; Sarah R Kingsbury; Gareth H Williams; Kai Stoeber; David L Selwood
Modular assembly using sequential palladium coupling gives easy access to the SMoC class of cellular transporters.
Chembiochem : a European journal of chemical biology 2008;9(11):1787-96.
2008: Lakshmana Ayaru; Kai Stoeber; George J M Webster; Adrian R W Hatfield; A Wollenschlaeger; O Okoturo; M Rashid; G Williams; Stephen P Pereira
Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in bile aspirates.
British journal of cancer 2008;98(9):1548-54.
2007: Gareth H Williams; Kai Stoeber
Cell cycle markers in clinical oncology.
Current opinion in cell biology 2007;19(6):672-9.
2007: Julie E Simpson; Paul Geoffrey Ince; C E Higham; Catherine H Gelsthorpe; Malee S Fernando; Fiona Matthews; Gill Forster; John T O'Brien; Robert Barber; Rajesh N. Kalaria; Carol Brayne; Pamela J Shaw; Kai Stoeber; Gareth H Williams; Claire E Lewis; Stephen B Wharton
Microglial activation in white matter lesions and nonlesional white matter of ageing brains.
Neuropathology and applied neurobiology 2007;33(6):670-83.
2007: Anjana A Kulkarni; Marco Loddo; Elisabetta Leo; Mohammed Rashid; Kathryn Leigh Eward; Thomas Fanshawe; Jessica Butcher; Alison Frost; Jonathan A Ledermann; Gareth H Williams; Kai Stoeber
DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6153-61.
2007: Laura R Barkley; Hye Kyung Hong; Sarah R Kingsbury; Michelle James; Kai Stoeber; Gareth H Williams
Cdc6 is a rate-limiting factor for proliferative capacity during HL60 cell differentiation.
Experimental cell research 2007;313(17):3789-99.
2007: Andrei L Okorokov; Alastair Waugh; Julie Hodgkinson; Andal Murthy; Hye Kyung Hong; Elisabetta Leo; Michael B Sherman; Kai Stoeber; Elena V Orlova; Gareth H Williams
Hexameric ring structure of human MCM10 DNA replication factor.
EMBO reports 2007;8(10):925-30.
2007: Tim J Dudderidge; S R McCracken; Marco Loddo; Thomas Fanshawe; J D Kelly; D E Neal; Hing Y Leung; Gareth H Williams; Kai Stoeber
Mitogenic growth signalling, DNA replication licensing, and survival are linked in prostate cancer.
British journal of cancer 2007;96(9):1384-93.
2007: Masahiro Okuyama; Heike Laman; Sarah R Kingsbury; Cristina Visintin; Elisabetta Leo; Kathryn Leigh Eward; Kai Stoeber; Chris Boshoff; Gareth H Williams; David L Selwood
Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells.
Nature methods 2007;4(2):153-9.
2007: Stephen B Wharton; Edna Maltby; David A Jellinek; D Levy; N Atkey; S Hibberd; Darach Crimmins; Kai Stoeber; Gareth H Williams
Subtypes of oligodendroglioma defined by 1p,19q deletions, differ in the proportion of apoptotic cells but not in replication-licensed non-proliferating cells.
Acta neuropathologica 2007;113(2):119-27.
2006: Alberto Quaglia; Mary McStay; Kai Stoeber; Marco Loddo; Martyn E Caplin; Thomas Fanshawe; Gareth Williams; Amar Dhillon
Novel markers of cell kinetics to evaluate progression from cirrhosis to hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(4):424-32.
2005: Maria Thom; Lillian Martinian; Sanjay M Sisodiya; J Helen Cross; G Williams; Kai Stoeber; William Harkness; Brian Harding
Mcm2 labelling of balloon cells in focal cortical dysplasia.
Neuropathology and applied neurobiology 2005;31(6):580-8.
2005: A Shetty; Marco Loddo; Thomas Fanshawe; A Toby Prevost; R Sainsbury; Gareth H Williams; Kai Stoeber
DNA replication licensing and cell cycle kinetics of normal and neoplastic breast.
British journal of cancer 2005;93(11):1295-300.
2005: Sarah R Kingsbury; Marco Loddo; Thomas Fanshawe; Ellen C Obermann; A Toby Prevost; Kai Stoeber; Gareth H Williams
Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells.
Experimental cell research 2005;309(1):56-67.
2005: Stephen B Wharton; Gareth H Williams; Kai Stoeber; Catherine H Gelsthorpe; Lynne Baxter; Anthony L Johnson; Paul Geoffrey Ince
Expression of Ki67, PCNA and the chromosome replication licensing protein Mcm2 in glial cells of the ageing human hippocampus increases with the burden of Alzheimer-type pathology.
Neuroscience letters 2005;383(1-2):33-8.
2005: Tim J Dudderidge; Kai Stoeber; Marco Loddo; Geraldine Atkinson; Thomas Fanshawe; David F Griffiths; Gareth H Williams
Mcm2, Geminin, and KI67 define proliferative state and are prognostic markers in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2510-7.
2005: Maria Thom; Lillian Martinian; Gareth Williams; Kai Stoeber; Sanjay M Sisodiya
Cell proliferation and granule cell dispersion in human hippocampal sclerosis.
Journal of neuropathology and experimental neurology 2005;64(3):194-201.
2005: Ellen C Obermann; Kathryn Leigh Eward; Ahmet Dogan; Elizabeth A Paul; Marco Loddo; Philippa Munson; Gareth H Williams; Kai Stoeber
DNA replication licensing in peripheral B-cell lymphoma.
The Journal of pathology 2005;205(3):318-28.
2004: Jian-Hua Chen; Kai Stoeber; Sarah Kingsbury; Susan E Ozanne; Gareth H Williams; C Nicholas Hales
Loss of proliferative capacity and induction of senescence in oxidatively stressed human fibroblasts.
The Journal of biological chemistry 2004;279(47):49439-46.
2004: Kathryn Leigh Eward; Ellen C Obermann; sathyavageeswaran shreeram; Marco Loddo; Thomas Fanshawe; Craig Williams; Hyo-Il Jung; A Toby Prevost; Jackson Blow; Kai Stoeber; Gareth H Williams
DNA replication licensing in somatic and germ cells.
Journal of cell science 2004;117(Pt 24):5875-86.
2004: Andrei L Okorokov; Elena V Orlova; Sarah R Kingsbury; Claire Bagneris; Ulrich Gohlke; Gareth H Williams; Kai Stoeber
Molecular structure of human geminin.
Nature structural & molecular biology 2004;11(10):1021-2.
2004: Gareth H Williams; Robert Swinn; A Toby Prevost; P De Clive-Lowe; Ian Halsall; James J Going; C Nicholas Hales; Kai Stoeber; S J Middleton
Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates.
British journal of cancer 2004;91(4):714-9.
2004: Stephen B Wharton; S Hibberd; Kathryn Leigh Eward; Darach Crimmins; David A Jellinek; D Levy; Kai Stoeber; Gareth H Williams
DNA replication licensing and cell cycle kinetics of oligodendroglial tumours.
British journal of cancer 2004;91(2):262-9.
2003: Nicholas C Lea; Stephen J Orr; Kai Stoeber; Gareth H Williams; Eric W-F Lam; Mohammad A A Ibrahim; Ghulam J Mufti; N Shaun B Thomas
Commitment point during G0-->G1 that controls entry into the cell cycle.
Molecular and cellular biology 2003;23(7):2351-61.
2002: Kai Stoeber; Robert Swinn; A Toby Prevost; Pamela de Clive-Lowe; Ian Halsall; Stephen M Dilworth; Jackie Marr; William H Turner; Nigel Bullock; Andrew Doble; C Nicholas Hales; Gareth H Williams
Diagnosis of genito-urinary tract cancer by detection of minichromosome maintenance 5 protein in urine sediments.
Journal of the National Cancer Institute 2002;94(14):1071-9.
2002: James J Going; Nicol Keith; Lisa J Neilson; Kai Stoeber; Robert C Stuart; G H Williams
Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa.
Gut 2002;50(3):373-7.
2001: M V Meng; G D Grossfeld; G H Williams; S Dilworth; Kai Stoeber; T W Mulley; V Weinberg; P R Carroll; Thea D Tlsty
Minichromosome maintenance protein 2 expression in prostate: characterization and association with outcome after therapy for cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2712-8.
2001: Stephen B Wharton; K K Chan; J R Anderson; Kai Stoeber; Gareth H Williams
Replicative Mcm2 protein as a novel proliferation marker in oligodendrogliomas and its relationship to Ki67 labelling index, histological grade and prognosis.
Neuropathology and applied neurobiology 2001;27(4):305-13.
2001: Kai Stoeber; Thea D Tlsty; Lisa Happerfield; G A Thomas; S Romanov; Lynda Bobrow; E D Williams; Gareth H Williams
DNA replication licensing and human cell proliferation.
Journal of cell science 2001;114(Pt 11):2027-41.
1999: Kai Stoeber; Ian Halsall; A Freeman; Robert Swinn; A Doble; L Morris; N Coleman; N Bullock; Ronald A Laskey; C N Hales; G H Williams
Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine.
Lancet 1999;354(9189):1524-5.
1999: A Freeman; Lesley S Morris; Anthony D Mills; Kai Stoeber; Ronald A Laskey; Gareth H Williams; Nicholas Coleman
Minichromosome maintenance proteins as biological markers of dysplasia and malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(8):2121-32.
1999: G Williams; Kai Stoeber
Clinical applications of a novel mammalian cell-free DNA replication system.
British journal of cancer 1999;80 Suppl 1():20-4.
1998: Kai Stoeber; Anthony D Mills; Y Kubota; Torsten Krude; P Romanowski; Kathrin Marheineke; Ronald A Laskey; Gareth H Williams
Cdc6 protein causes premature entry into S phase in a mammalian cell-free system.
The EMBO journal 1998;17(24):7219-29.
1998: Gareth H Williams; P Romanowski; L Morris; Mark A Madine; Anthony D Mills; Kai Stoeber; Jackie Marr; Ronald A Laskey; Nicholas Coleman
Improved cervical smear assessment using antibodies against proteins that regulate DNA replication.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14932-7.