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Jan Stoehlmacher

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Heidi Schwarzenbach; Eray Goekkurt; Klaus Pantel; Daniela E Aust; Jan Stoehlmacher
Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
Gunnar Folprecht; Thomas Gruenberger; Wolf O Bechstein; Hans-Rudolf Raab; Florian Lordick; Jörg T Hartmann; Hauke Lang; Andrea Frilling; Jan Stoehlmacher; Jürgen Weitz; Ralf Konopke; Christian Stroszczynski; Torsten Liersch; Detlev Ockert; Thomas Herrmann; Eray Goekkurt; Fabio Parisi; Claus-Henning Köhne
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial.
Ulrike Mogck; Eray Goekkurt; Jan Stoehlmacher
The EGFR pathway as an example for genotype: phenotype correlation in tumor genes.

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All Publications

2010: Heidi Schwarzenbach; Eray Goekkurt; Klaus Pantel; Daniela E Aust; Jan Stoehlmacher
Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
International journal of cancer. Journal international du cancer 2010;127(4):881-8.
2010: Gunnar Folprecht; Thomas Gruenberger; Wolf O Bechstein; Hans-Rudolf Raab; Florian Lordick; Jörg T Hartmann; Hauke Lang; Andrea Frilling; Jan Stoehlmacher; Jürgen Weitz; Ralf Konopke; Christian Stroszczynski; Torsten Liersch; Detlev Ockert; Thomas Herrmann; Eray Goekkurt; Fabio Parisi; Claus-Henning Köhne
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial.
The lancet oncology 2010;11(1):38-47.
2010: Ulrike Mogck; Eray Goekkurt; Jan Stoehlmacher
The EGFR pathway as an example for genotype: phenotype correlation in tumor genes.
Methods in molecular biology (Clifton, N.J.) 2010;576():341-50.
2009: Eray Goekkurt; Salah-Eddin Al-Batran; Jörg Thomas Hartmann; Ulrike Mogck; Gunter Schuch; Michael Kramer; Elke Jaeger; Carsten Bokemeyer; Gerhard Ehninger; Jan Stoehlmacher
Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft internistische onkologie.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(17):2863-73.
2009: Eray Goekkurt; S-E Al-Batran; U Mogck; C Pauligk; J T Hartmann; M Kramer; E Jaeger; Gerhard Ehninger; Jan Stoehlmacher
Pharmacogenetic analyses of hematotoxicity in advanced gastric cancer patients receiving biweekly fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(3):481-5.
2009: Uwe Platzbecker; M von Bonin; Eray Goekkurt; Jörgen Radke; Marc Binder; Alexander Kiani; Jan Stoehlmacher; Johannes Schetelig; Christian Thiede; Gerhard Ehninger; Martin Bornhäuser
Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(1):101-8.
2008: Jan Stoehlmacher; Eray Goekkurt; Ulrike Mogck; Daniela E Aust; Michael Kramer; Gustavo B Baretton; Torsten Liersch; Gerhard Ehninger; Christiane Jakob
Thymidylate synthase genotypes and tumour regression in stage II/III rectal cancer patients after neoadjuvant fluorouracil-based chemoradiation.
Cancer letters 2008;272(2):221-5.
2008: Salah-Eddin Al-Batran; Jörg Thomas Hartmann; R Hofheinz; N Homann; V Rethwisch; S Probst; Jan Stoehlmacher; M R Clemens; R Mahlberg; M Fritz; Gernot Seipelt; M Sievert; Claudia Pauligk; Akin Atmaca; Elke Jäger
Biweekly fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) for patients with metastatic adenocarcinoma of the stomach or esophagogastric junction: a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(11):1882-7.
2008: Heidi Schwarzenbach; Jan Stoehlmacher; Klaus Pantel; Eray Goekkurt
Detection and monitoring of cell-free DNA in blood of patients with colorectal cancer.
Annals of the New York Academy of Sciences 2008;1137():190-6.
2008: Salah-Eddin Al-Batran; Jörg Thomas Hartmann; Stephan Probst; Harald Schmalenberg; Stephan Hollerbach; Ralf Hofheinz; Volker Rethwisch; Gernot Seipelt; Nils Homann; Gerhard Wilhelm; Gunter Schuch; Jan Stoehlmacher; Hans Günter Derigs; Susanna Hegewisch-Becker; Johannes Grossmann; Claudia Pauligk; Akin Atmaca; Carsten Bokemeyer; Alexander Knuth; Elke Jäger
Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(9):1435-42.
2007: Eray Goekkurt; Jan Stoehlmacher; Christian Stueber; Christine Wolschke; Thomas Eiermann; Simona Iacobelli; Axel R Zander; Gerhard Ehninger; Nicolaus Kröger
Pharmacogenetic analysis of liver toxicity after busulfan/cyclophosphamide-based allogeneic hematopoietic stem cell transplantation.
Anticancer research 2007;27(6C):4377-80.
2007: Salah-Eddin Al-Batran; Jörg Thomas Hartmann; Florian Heidel; Jan Stoehlmacher; Eva Wardelmann; Claudius Dechow; Markus Düx; Jacob Robert Izbicki; Thomas Kraus; Thomas Fischer; Elke Jäger
Focal progression in patients with gastrointestinal stromal tumors after initial response to imatinib mesylate: a three-center-based study of 38 patients.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2007;10(3):145-52.
2007: Jan Stoehlmacher
Prediction of efficacy and side effects of chemotherapy in colorectal cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2007;176():81-8.
2006: Eray Goekkurt; S Hoehn; Christine Wolschke; C Wittmer; C Stueber; Dieter K Hossfeld; Jan Stoehlmacher
Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS)--novel predictors for response and survival in gastric cancer patients.
British journal of cancer 2006;94(2):281-6.
2005: Eray Goekkurt; Jan Stoehlmacher
Current pharmacogenetics in colorectal cancer--do they have an impact on our clinical treatment strategies?
International journal of clinical pharmacology and therapeutics 2005;43(12):577-8.
2005: Christine Wolschke; Eray Goekkurt; Salah-Eddin Al-Batran; Dieter K Hossfeld; Jan Stoehlmacher
Pharmacogenetics of extraordinary responses to 5-FU/cisplatin chemotherapy in advanced gastric cancer -- report of 2 cases.
Onkologie 2005;28(11):589-92.
2005: Wu Zhang; Jan Stoehlmacher; David J Park; Dongyun Yang; Erin Borchard; Ji Gil; Denice D Tsao-Wei; Jim Yun; Michael Gordon; Oliver A Press; Katrin Rhodes; Susan Groshen; Heinz-Josef Lenz
Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.
Clinical colorectal cancer 2005;5(2):124-31.
2005: Alexandra Nieters; Jian-Min Yuan; Canlan Sun; Zhen-Quan Zhang; Jan Stoehlmacher; Sugantha Govindarajan; Mimi C Yu
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association.
Cancer 2005;103(4):740-8.
2004: Michael V Mandola; Jan Stoehlmacher; Wu Zhang; Susan Groshen; Mimi C Yu; Syma Iqbal; Heinz-Josef Lenz; Robert D Ladner
A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels.
Pharmacogenetics 2004;14(5):319-27.
2004: Syma Iqbal; Jan Stoehlmacher; Heinz-Josef Lenz
Tailored chemotherapy for colorectal cancer: a new approach to therapy.
Cancer investigation 2004;22(5):762-73.
2003: Jan Stoehlmacher; Eray Goekkurt; Heinz-Josef Lenz
Pharmacogenetic aspects in treatment of colorectal cancer--an update.
Pharmacogenomics 2003;4(6):767-77.
2003: David J Park; Jan Stoehlmacher; Heinz-Josef Lenz
Tailoring chemotherapy in advanced colorectal cancer.
Current opinion in pharmacology 2003;3(4):378-85.
2003: Jan Stoehlmacher; Heinz-Josef Lenz
Cyclooxygenase-2 inhibitors in colorectal cancer.
Seminars in oncology 2003;30(3 Suppl 6):10-6.
2003: Michael V Mandola; Jan Stoehlmacher; Susan Muller-Weeks; Gregory Cesarone; Mimi C Yu; Heinz-Josef Lenz; Robert D Ladner
A novel single nucleotide polymorphism within the 5' tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity.
Cancer research 2003;63(11):2898-904.
2003: David J Park; Wu Zhang; Jan Stoehlmacher; Denice D Tsao-Wei; Susan Groshen; Ji Gil; Jim Yun; Erin Sones; Nalin Mallik; Heinz-Josef Lenz
ERCC1 gene polymorphism as a predictor for clinical outcome in advanced colorectal cancer patients treated with platinum-based chemotherapy.
Clinical advances in hematology & oncology : H&O 2003;1(3):162-6.
2003: Jan Stoehlmacher; Heinz-Josef Lenz
Implications of genetic testing in the management of colorectal cancer.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 2003;3(2):73-88.
2002: Jan Stoehlmacher; David J Park; Wu Zhang; Susan Groshen; Denice D Tsao-Wei; Mimi C Yu; Heinz-Josef Lenz
Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer.
Journal of the National Cancer Institute 2002;94(12):936-42.
2002: Jan Stoehlmacher; Sue A Ingles; David J Park; Wu Zhang; Heinz-Josef Lenz
The -9Ala/-9Val polymorphism in the mitochondrial targeting sequence of the manganese superoxide dismutase gene (MnSOD) is associated with age among Hispanics with colorectal carcinoma.
Oncology reports 2002;9(2):235-8.
2002: David J Park; Jan Stoehlmacher; Wu Zhang; Denice D Tsao-Wei; Susan Groshen; Heinz-Josef Lenz
Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer.
International journal of colorectal disease 2002;17(1):46-9.
2001: David J Park; Jan Stoehlmacher; Wu Zhang; Denice D Tsao-Wei; Susan Groshen; Heinz-Josef Lenz
A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer.
Cancer research 2001;61(24):8654-8.
2001: Yoshinori Shirota; Jan Stoehlmacher; Jan Brabender; YP Xiong; Hiroyuki Uetake; Kathleen D Danenberg; Susan Groshen; Denice D Tsao-Wei; Peter V Danenberg; Heinz-Josef Lenz
ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(23):4298-304.
2001: Jan Stoehlmacher; V Ghaderi; S Iobal; Susan Groshen; Denice D Tsao-Wei; D Park; Heinz-Josef Lenz
A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer.
Anticancer research 2001;21(4B):3075-9.
2001: Sheeja T Pullarkat; Jan Stoehlmacher; V Ghaderi; YP Xiong; Sue A Ingles; Andy E Sherrod; R Warren; Denice D Tsao-Wei; Susan Groshen; Heinz-Josef Lenz
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy.
The pharmacogenomics journal 2001;1(1):65-70.
2000: Robert D Ladner; F J Lynch; Susan Groshen; YP Xiong; Andy E Sherrod; Sal Caradonna; Jan Stoehlmacher; Heinz-Josef Lenz
dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer.
Cancer research 2000;60(13):3493-503.