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Soon Kil Ahn

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TOP 3
Ky-Youb Nam; Nam Song Choi; Cheol Kyu Han; Soon Kil Ahn
Identification of chalcones as potent and selective PDE5A1 inhibitors.
Jaekwang Lee; Suyeal Bae; Seo-Hee Lee; Hojin Choi; Young Hoon Kim; Soo Jin Kim; Gyu Tae Park; Seung Kee Moon; Dal-Hyun Kim; Sungsook Lee; Soon Kil Ahn; Nam Song Choi; Kyung Joo Lee
Discovery of a potent tubulin polymerization inhibitor: synthesis and evaluation of water-soluble prodrugs of benzophenone analog.
Jaekwang Lee; Soo Jin Kim; Hojin Choi; Young Hoon Kim; In Taek Lim; Hyun-mo Yang; Chang Sik Lee; Hee Ryong Kang; Soon Kil Ahn; Seung Kee Moon; Dal-Hyun Kim; Sungsook Lee; Nam Song Choi; Kyung Joo Lee
Identification of CKD-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.

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2012: Ky-Youb Nam; Nam Song Choi; Cheol Kyu Han; Soon Kil Ahn
Identification of chalcones as potent and selective PDE5A1 inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(12):3983-7.
2010: Jaekwang Lee; Suyeal Bae; Seo-Hee Lee; Hojin Choi; Young Hoon Kim; Soo Jin Kim; Gyu Tae Park; Seung Kee Moon; Dal-Hyun Kim; Sungsook Lee; Soon Kil Ahn; Nam Song Choi; Kyung Joo Lee
Discovery of a potent tubulin polymerization inhibitor: synthesis and evaluation of water-soluble prodrugs of benzophenone analog.
Bioorganic & medicinal chemistry letters 2010;20(21):6327-30.
2010: Jaekwang Lee; Soo Jin Kim; Hojin Choi; Young Hoon Kim; In Taek Lim; Hyun-mo Yang; Chang Sik Lee; Hee Ryong Kang; Soon Kil Ahn; Seung Kee Moon; Dal-Hyun Kim; Sungsook Lee; Nam Song Choi; Kyung Joo Lee
Identification of CKD-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors.
Journal of medicinal chemistry 2010;53(17):6337-54.
2010: Hojin Choi; Jaekwang Lee; Young Hoon Kim; Dai Sig Im; In-Chang Hwang; Soo Jin Kim; Seung Kee Moon; Hong Woo Lee; Sung Sook Lee; Soon Kil Ahn; Sang Woong Kim; Nam Song Choi; Kyung Joo Lee
Discovery of potent, selective, and orally bioavailable PDE5 inhibitor: Methyl-4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-ylmethylcarbamate (CKD 533).
Bioorganic & medicinal chemistry letters 2010;20(1):383-6.
2008: Young Hoon Kim; Hojin Choi; Jaekwang Lee; In-Chang Hwang; Seung Kee Moon; Soo Jin Kim; Hong Woo Lee; Dai Sig Im; Sung Sook Lee; Soon Kil Ahn; Sang Woong Kim; Cheol Kyu Han; Jeong Hyeok Yoon; Kyung Joo Lee; Nam Song Choi
Quinazolines as potent and highly selective PDE5 inhibitors as potential therapeutics for male erectile dysfunction.
Bioorganic & medicinal chemistry letters 2008;18(23):6279-82.
2008: Min-Hyo Ki; Mee-Hwa Choi; Kwang-Bok Ahn; Byoung-Su Kim; Dai Sig Im; Soon Kil Ahn; Hee-Jong Shin
The efficacy and safety of clopidogrel resinate as a novel polymeric salt form of clopidogrel.
Archives of pharmacal research 2008;31(2):250-8.
2007: Hong Woo Lee; Chin Sung Cho; Sung Kwon Kang; Yong Sang Yoo; Jae Soo Shin; Soon Kil Ahn
Design, synthesis, and antiangiogenic effects of a series of potent novel fumagillin analogues.
Chemical & pharmaceutical bulletin 2007;55(7):1024-9.
2007: Jin-Kyung In; Mi-Sung Lee; Jung-Eun Yang; Jae-Hwan Kwak; Heesoon Lee; Shanthaveerappa K Boovanahalli; Kyeong Lee; Soo Jin Kim; Seung Kee Moon; Sungsook Lee; Nam Song Choi; Soon Kil Ahn; Jae-Kyung Jung
Synthesis of novel diaryl ethers and their evaluation as antimitotic agents.
Bioorganic & medicinal chemistry letters 2007;17(6):1799-802.
2005: Hong Woo Lee; Bok Young Kim; Joong Bok Ahn; Sung Kwon Kang; Jung Hwa Lee; Jae Soo Shin; Soon Kil Ahn; Sang Joon Lee; Seung Soo Yoon
Molecular design, synthesis, and hypoglycemic and hypolipidemic activities of novel pyrimidine derivatives having thiazolidinedione.
European journal of medicinal chemistry 2005;40(9):862-74.
2005: Byeong-Seon Jeong; Nam Song Choi; Soon Kil Ahn; Hoon Bae; Hak-Sung Kim; Deukjoon Kim
Total synthesis and antiangiogenic activity of cyclopentane analogues of fumagillol.
Bioorganic & medicinal chemistry letters 2005;15(15):3580-3.
2004: Bok Young Kim; Joong Bok Ahn; Hong Woo Lee; Sung Kwon Kang; Jung Hwa Lee; Jae Soo Shin; Soon Kil Ahn; Chung Il Hong; Seung Soo Yoon
Synthesis and biological activity of novel substituted pyridines and purines containing 2,4-thiazolidinedione.
European journal of medicinal chemistry 2004;39(5):433-47.
2004: Deukjoon Kim; Jaeki Min; Soon Kil Ahn; Hong Woo Lee; Nam Song Choi; Seung Kee Moon
5-Demethoxyfumagillol, a potent angiogenesis inhibitor isolated from Aspergillus fumigatus.
Chemical & pharmaceutical bulletin 2004;52(4):447-50.
2004: Jae-Hyun Kim; Su-Kyung Lee; Min-Hyo Ki; Won-Kyu Choi; Soon Kil Ahn; Hee-Jong Shin; Chung Il Hong
Development of parenteral formulation for a novel angiogenesis inhibitor, CKD-732 through complexation with hydroxypropyl-beta-cyclodextrin.
International journal of pharmaceutics 2004;272(1-2):79-89.
2004: Ho Sup Lee; Won-Kyu Choi; Hyeog-Jin Son; Sung Sook Lee; Joon Kyum Kim; Soon Kil Ahn; Chung Il Hong; Hye-Ki Min; Myungsoo Kim; Seung-Woon Myung
Absorption, distribution, metabolism, and excretion of CKD-732, a novel antiangiogenic fumagillin derivative, in rats, mice, and dogs.
Archives of pharmacal research 2004;27(2):265-72.
2003: Bok Young Kim; Joong Bok Ahn; Hong Woo Lee; Kyoung Sik Moon; Tae Bo Sim; Jae Soo Shin; Soon Kil Ahn; Chung Il Hong
Synthesis and antihyperglycemic activity of erythrose, ribose and substituted pyrrolidine containing thiazolidinedione derivatives.
Chemical & pharmaceutical bulletin 2003;51(3):276-85.
2002: Hung-Bae Chang; Sun-Ho Kim; Young-In Kwon; Dong-Ho Choung; Won-Kyu Choi; Tae Won Kang; Sungsook Lee; Jong-Gwan Kim; Hyoung-Sik Chun; Soon Kil Ahn; Chung Il Hong; Kyou-Hoon Han
Novel alpha-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp. CK-4416. III. Physico-chemical properties and structure elucidation.
The Journal of antibiotics 2002;55(5):467-71.
2002: Young-In Kwon; Hyeog-Jin Son; Kyoung Sik Moon; Joon Kyum Kim; Jong-Gwan Kim; Hyoung-Sik Chun; Soon Kil Ahn; Chung Il Hong
Novel alpha-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp. CK-4416. II. Biological properties.
The Journal of antibiotics 2002;55(5):462-6.
2002: Jong-Gwan Kim; Hung-Bae Chang; Young-In Kwon; Seung-Kee Moon; Hyoung-Sik Chun; Soon Kil Ahn; Chung Il Hong
Novel alpha-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp. CK-4416. I. Taxonomy, fermentation and isolation.
The Journal of antibiotics 2002;55(5):457-61.
2000: C K Han; Soon Kil Ahn; Nam Song Choi; R K Hong; Seung Kee Moon; H S Chun; S J Lee; J W Kim; Chung Il Hong; Deukjoon Kim; J H Yoon; K T No
Design and synthesis of highly potent fumagillin analogues from homology modeling for a human MetAP-2.
Bioorganic & medicinal chemistry letters 2000;10(1):39-43.
2000: J H Lee; J M Lee; K H Lim; Joon Kyum Kim; Soon Kil Ahn; Y J Bang; Chung Il Hong
Preclinical and phase I clinical studies with Ckd-602, a novel camptothecin derivative.
Annals of the New York Academy of Sciences 2000;922():324-5.
1998: J H Lee; J M Lee; Joon Kyum Kim; Soon Kil Ahn; S J Lee; M Y Kim; Sang-sup Jew; J G Park; Chung Il Hong
Antitumor activity of 7-[2-(N-isopropylamino)ethyl]-(20S)-camptothecin, CKD602, as a potent DNA topoisomerase I inhibitor.
Archives of pharmacal research 1998;21(5):581-90.
1997: H W Lee; E N Kim; T W Kang; Soon Kil Ahn; N H Choi; J W Kim; Chung Il Hong
Synthesis and structure-activity relationship of 2-(5-substituted pyrrolidin-4-ylthio)-1 beta-carbapenems.
The Journal of antibiotics 1997;50(12):1078-82.