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Walter Storkus

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Brian M Janelsins; Geza Erdos; Louis D Falo; Alicia R Mathers; Adrian E Morelli; Darling M Rojas-Canales; William J Shufesky; Walter J Storkus; Tina L Sumpter; Olga A Tkacheva; Adriana T Larregina
Neurokinin-1 receptor agonists bias therapeutic dendritic cells to induce type 1 immunity by licensing host dendritic cells to produce IL-12.
Aparna Rao; Nina Chi-Sabins; William E Gooding; Mayumi Kawabe; Jennifer L Taylor; Walter J Storkus
Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells.
Anamika Bose; Devin B Lowe; Aparna Rao; Walter J Storkus
Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model.

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All Publications

2013: Brian M Janelsins; Geza Erdos; Louis D Falo; Alicia R Mathers; Adrian E Morelli; Darling M Rojas-Canales; William J Shufesky; Walter J Storkus; Tina L Sumpter; Olga A Tkacheva; Adriana T Larregina
Neurokinin-1 receptor agonists bias therapeutic dendritic cells to induce type 1 immunity by licensing host dendritic cells to produce IL-12.
Blood 2013;121(15):2923-33.
2012: Aparna Rao; Nina Chi-Sabins; William E Gooding; Mayumi Kawabe; Jennifer L Taylor; Walter J Storkus
Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells.
Cancer research 2012;72(13):3196-206.
2012: Anamika Bose; Devin B Lowe; Aparna Rao; Walter J Storkus
Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model.
Melanoma research 2012;22(3):236-43.
2012: Yanyan Qu; Walter J Storkus; Lu Chen; Devin B Lowe; Jennifer L Taylor
Combined Tbet and IL12 gene therapy elicits and recruits superior antitumor immunity in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(3):644-51.
2012: Xi Zhao; Jennifer L Taylor; Anamika Bose; Ying Cao; Nina Chi; Peter A Cohen; Hideo Komita; Devin B Lowe; Debabrata Mukhopadhyay; Hideho Okada; Walter J Storkus
Vaccines targeting tumor blood vessel antigens promote CD8(+) T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):1782-8.
2012: Peter A Cohen; Anna Lucia Dominguez; Judy M Bradley; Sandra J Gendler; Jessica E Gorman; Jennifer S Ko; Dustin B McCurry; Latha B Pathangey; Patricia A Rayman; Brian I Rini; Christopher D Spencer; Walter J Storkus; Soroya Zorro-Manrique; James H Finke
Myeloid-derived suppressor cells adhere to physiologic STAT3- vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape.
Immunological investigations 2012;41(6-7):680-710.
2011: Anamika Bose; Peter A Cohen; James H Finke; Jorge A Garcia; Jennifer S Ko; Brian I Rini; Jennifer L Taylor; Simon C Watkins; Sean Alber; Walter J Storkus
Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination.
International journal of cancer. Journal international du cancer 2011;129(9):2158-70.
2011: Devin B Lowe; Walter J Storkus
Chronic inflammation and immunologic-based constraints in malignant disease.
Immunotherapy 2011;3(10):1265-74.
2011: Y Qu; A Bose; J L Taylor; Walter J Storkus
Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32.
Cancer gene therapy 2011;18(9):663-73.
2011: Xi Zhao; Anamika Bose; Hideo Komita; Jennifer L Taylor; Mayumi Kawabe; Nina Chi; Laima Spokas; Devin B Lowe; Christina Goldbach; Sean Alber; Simon C Watkins; Lisa H Butterfield; Pawel Kalinski; John M Kirkwood; Walter J Storkus
Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):805-14.
2010: Angela D Pardee; Dustin McCurry; Sean Alber; Peisheng Hu; Alan L Epstein; Walter J Storkus
A therapeutic OX40 agonist dynamically alters dendritic, endothelial, and T cell subsets within the established tumor microenvironment.
Cancer research 2010;70(22):9041-52.
2010: Yanyan Qu; Lu Chen; Angela D Pardee; Jennifer L Taylor; Amy Wesa; Walter J Storkus
Intralesional delivery of dendritic cells engineered to express T-bet promotes protective type 1 immunity and the normalization of the tumor microenvironment.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(5):2895-902.
2010: Michael W Lipscomb; Jennifer L Taylor; Cristina J Goldbach; simon simon watkins; Amy K Wesa; Walter J Storkus
DC expressing transgene Foxp3 are regulatory APC.
European journal of immunology 2010;40(2):480-93.
2010: Elisabetta Cavalcanti; Margherita Gigante; Vito Mancini; Michele Battaglia; Pasquale Ditonno; Carmela Capobianco; Raffaele I Cincione; Francesco P Selvaggi; Wolfgang Herr; Walter J Storkus; Loreto Gesualdo; Elena Ranieri
JAK3/STAT5/6 pathway alterations are associated with immune deviation in CD8 T cells in renal cell carcinoma patients.
Journal of biomedicine & biotechnology 2010;2010():935764.
2009: Michael W Lipscomb; Lu Chen; Jennifer L Taylor; Christina Goldbach; simon simon watkins; Pawel Kalinski; Lisa H Butterfield; Amy K Wesa; Walter J Storkus
Ectopic T-bet expression licenses dendritic cells for IL-12-independent priming of type 1 T cells in vitro.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7250-8.
2009: Hideo Komita; X Zhao; Anand kumar katakam; P Kumar; M Kawabe; Hideho Okada; J M Braughler; Walter J Storkus
Conditional interleukin-12 gene therapy promotes safe and effective antitumor immunity.
Cancer gene therapy 2009;16(12):883-91.
2009: Kotaro Sasaki; Angela D Pardee; Yanyan Qu; Xi Zhao; Ryo Ueda; Gary Kohanbash; Lisa M Bailey; Hideho Okada; Ravikumar Muthuswamy; Pawel Kalinski; Per H Basse; Louis D Falo; Walter J Storkus
IL-4 suppresses very late antigen-4 expression which is required for therapeutic Th1 T-cell trafficking into tumors.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(8):793-802.
2009: Eva U Wieckowski; Carmen Visus; Marta Szajnik; Miroslaw J Szczepanski; Walter J Storkus; Theresa L Whiteside
Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):3720-30.
2009: Mayumi Kawabe; Maja Mandic; Jennifer L Taylor; Cecilia A Vasquez; Amy Wesa; Leonard M Neckers; Walter J Storkus
Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.
Cancer research 2009;69(17):6995-7003.
2009: Angela D Pardee; Amy Wesa; Walter J Storkus
Integrating costimulatory agonists to optimize immune-based cancer therapies.
Immunotherapy 2009;1(2):249-64.
2008: Amy Wesa; Christopher J Herrem; Maja Mandic; Jennifer L Taylor; Cecilia Vasquez; Mayumi Kawabe; Tomohide Tatsumi; Michael S Leibowitz; James H Finke; Ronald M Bukowski; Elizabeth M Bruckheimer; Michael S Kinch; Walter J Storkus
Enhancement in specific CD8+ T cell recognition of EphA2+ tumors in vitro and in vivo after treatment with ligand agonists.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7721-7.
2008: Kotaro Sasaki; Angela D Pardee; Hideho Okada; Walter J Storkus
IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit.
European journal of immunology 2008;38(10):2865-73.
2008: Hideo Komita; Xi Zhao; Jennifer L Taylor; Louis J Sparvero; Andrew A Amoscato; Sean Alber; simon simon watkins; Angela D Pardee; Amy Wesa; Walter J Storkus
CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growth.
Cancer research 2008;68(19):8076-84.
2008: Kotaro Sasaki; Xi Zhao; Angela D Pardee; Ryo Ueda; Mitsugu Fujita; Sarita Sehra; Mark H Kaplan; Lawrence P Kane; Hideho Okada; Walter J Storkus
Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):104-8.
2008: Stergios J Moschos; Maja Mandic; John M Kirkwood; Walter J Storkus; Michael T Lotze
Focus on FOCIS: interleukin 2 treatment associated autoimmunity.
Clinical immunology (Orlando, Fla.) 2008;127(2):123-9.
2008: Margherita Gigante; Maja Mandic; Amy Wesa; Elisabetta Cavalcanti; Michele Dambrosio; Vito Mancini; Michele Battaglia; Loreto Gesualdo; Walter J Storkus; Elena Ranieri
Interferon-alpha (IFN-alpha)-conditioned DC preferentially stimulate type-1 and limit Treg-type in vitro T-cell responses from RCC patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(3):254-62.
2008: Amy Wesa; Walter J Storkus
Killer dendritic cells: mechanisms of action and therapeutic implications for cancer.
Cell death and differentiation 2008;15(1):51-7.
2007: Lazar Vujanovic; Maja Mandic; Walter C Olson; John M Kirkwood; Walter J Storkus
A mycoplasma peptide elicits heteroclitic CD4+ T cell responses against tumor antigen MAGE-A6.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6796-806.
2007: Yutaro Nakamura; Payal Watchmaker; Julie Urban; Brian Sheridan; Adam Giermasz; Fumihiko Nishimura; Kotaro Sasaki; Rachel Cumberland; Ravikumar Muthuswamy; Robbie B Mailliard; Adriana T Larregina; Louis Falo; William Gooding; Walter J Storkus; Hideho Okada; Robert L Hendricks; Pawel Kalinski
Helper function of memory CD8+ T cells: heterologous CD8+ T cells support the induction of therapeutic cancer immunity.
Cancer research 2007;67(20):10012-8.
2007: Shinjiro Yamaguchi; Tomohide Tatsumi; Tetsuo Takehara; Ryotaro Sakamori; Akio Uemura; Tsunekazu Mizushima; Kazuyoshi Ohkawa; Walter J Storkus; Norio Hayashi
Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines.
Cancer 2007;110(7):1469-77.
2007: Kotaro Sasaki; Xinmei Zhu; Cecilia Vasquez; Fumihiko Nishimura; Jill E Dusak; Jian Huang; Mitsugu Fujita; Amy Wesa; Douglas M Potter; Paul R Walker; Walter J Storkus; Hideho Okada
Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors.
Cancer research 2007;67(13):6451-8.
2007: Walter J Storkus
Melanoma vaccines: in search of a clinical paradigm.
Melanoma research 2007;17(3):137-8.
2007: Tomohide Tatsumi; Tetsuo Takehara; Shinjiro Yamaguchi; A Sasakawa; Takuya Miyagi; Masahisa Jinushi; Ryotaro Sakamori; Keisuke Kohga; Akio Uemura; Kazuyoshi Ohkawa; Walter J Storkus; Norio Hayashi
Injection of IL-12 gene-transduced dendritic cells into mouse liver tumor lesions activates both innate and acquired immunity.
Gene therapy 2007;14(11):863-71.
2007: iulia popescu; Camila Macedo; Kareem Abu-Elmagd; Ron Shapiro; Y Hua; Angus W Thomson; Adrian E Morelli; Walter J Storkus; Diana Metes
EBV-specific CD8+ T cell reactivation in transplant patients results in expansion of CD8+ type-1 regulatory T cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(5):1215-23.
2007: Aklile Berhanu; Jian Huang; simon simon watkins; Hideho Okada; Walter J Storkus
Treatment-enhanced CD4+Foxp3+ glucocorticoid-induced TNF receptor family related high regulatory tumor-infiltrating T cells limit the effectiveness of cytokine-based immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3400-8.
2007: Walter J Storkus; Christopher Herrem; Mayumi Kawabe; Peter A Cohen; Ronald M Bukowski; James H Finke; Amy Wesa
Improving immunotherapy by conditionally enhancing MHC class I presentation of tumor antigen-derived Peptide epitopes.
Critical reviews in immunology 2007;27(5):485-93.
2007: Xinmei Zhu; Fumihiko Nishimura; Kotaro Sasaki; Mitsugu Fujita; Jill E Dusak; Junichi Eguchi; Wendy Fellows-Mayle; Walter J Storkus; Paul R Walker; Andres M Salazar; Hideho Okada
Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models.
Journal of translational medicine 2007;5():10.
2007: Walter J Storkus; Louis Falo
A 'good death' for tumor immunology.
Nature medicine 2007;13(1):28-30.
2007: Amy Wesa; Pawel Kalinski; John M Kirkwood; Tomohide Tatsumi; Walter J Storkus
Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(1):75-82.
2006: Lazar Vujanovic; Elena Ranieri; Andrea Gambotto; Walter C Olson; John M Kirkwood; Walter J Storkus
IL-12p70 and IL-18 gene-modified dendritic cells loaded with tumor antigen-derived peptides or recombinant protein effectively stimulate specific Type-1 CD4+ T-cell responses from normal donors and melanoma patients in vitro.
Cancer gene therapy 2006;13(8):798-805.
2006: Junichi Eguchi; Manabu Hatano; Fumihiko Nishimura; Xinmei Zhu; Jill E Dusak; Hidemitsu Sato; Ian F Pollack; Walter J Storkus; Hideho Okada
Identification of interleukin-13 receptor alpha2 peptide analogues capable of inducing improved antiglioma CTL responses.
Cancer research 2006;66(11):5883-91.
2006: Aklile Berhanu; Jian Huang; Sean Alber; simon simon watkins; Walter J Storkus
Combinational FLt3 ligand and granulocyte macrophage colony-stimulating factor treatment promotes enhanced tumor infiltration by dendritic cells and antitumor CD8(+) T-cell cross-priming but is ineffective as a therapy.
Cancer research 2006;66(9):4895-903.
2006: Fumihiko Nishimura; Jill E Dusak; Junichi Eguchi; Xinmei Zhu; Andrea Gambotto; Walter J Storkus; Hideho Okada
Adoptive transfer of type 1 CTL mediates effective anti-central nervous system tumor response: critical roles of IFN-inducible protein-10.
Cancer research 2006;66(8):4478-87.
2006: Anna Wankowicz-Kalinska; Robbie B Mailliard; Kathleen Olson; Fiona Graham; Howard D Edington; John M Kirkwood; Stephanie Martinek; Pranab K Das; Walter J Storkus
Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation.
Melanoma research 2006;16(2):165-74.
2005: Jian Huang; Tomohide Tatsumi; Eva Pizzoferrato; Nikola L Vujanovic; Walter J Storkus
Nitric oxide sensitizes tumor cells to dendritic cell-mediated apoptosis, uptake, and cross-presentation.
Cancer research 2005;65(18):8461-70.
2005: Naruo Kuwashima; Fumihiko Nishimura; Junichi Eguchi; Hidemitsu Sato; Manabu Hatano; Takahiko Tsugawa; Tsukasa Sakaida; Jill E Dusak; Wendy Fellows-Mayle; Glenn D Papworth; simon simon watkins; Andrea Gambotto; Ian F Pollack; Walter J Storkus; Hideho Okada
Delivery of dendritic cells engineered to secrete IFN-alpha into central nervous system tumors enhances the efficacy of peripheral tumor cell vaccines: dependence on apoptotic pathways.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2730-40.
2005: Manabu Hatano; Junichi Eguchi; Tomohide Tatsumi; Naruo Kuwashima; Jill E Dusak; Michael S Kinch; Ian F Pollack; Ronald L Hamilton; Walter J Storkus; Hideho Okada
EphA2 as a glioma-associated antigen: a novel target for glioma vaccines.
Neoplasia (New York, N.Y.) 2005;7(8):717-22.
2005: Dominic E Warrino; Walter C Olson; Meera I Scarrow; Lori J D'Ambrosio-Brennan; Richard S Guido; Diane M Da Silva; W Martin Kast; Walter J Storkus
Human papillomavirus L1L2-E7 virus-like particles partially mature human dendritic cells and elicit E7-specific T-helper responses from patients with cervical intraepithelial neoplasia or cervical cancer in vitro.
Human immunology 2005;66(7):762-72.
2005: Jan Muller-Berghaus; Walter C Olson; Rachel A Moulton; William T Knapp; Dirk Schadendorf; Walter J Storkus
IL-12 production by human monocyte-derived dendritic cells: looking at the single cell.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(4):306-13.
2005: Camila Macedo; Albert D Donnenberg; iulia popescu; Jorge Reyes; Kareem Abu-Elmagd; Ron Shapiro; Adriana Zeevi; John J Fung; Walter J Storkus; Diana Metes
EBV-specific memory CD8+ T cell phenotype and function in stable solid organ transplant patients.
Transplant immunology 2005;14(2):109-16.
2005: Junichi Eguchi; Naruo Kuwashima; Manabu Hatano; Fumihiko Nishimura; Jill E Dusak; Walter J Storkus; Hideho Okada
IL-4-transfected tumor cell vaccines activate tumor-infiltrating dendritic cells and promote type-1 immunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7194-201.
2005: Camila Macedo; iulia popescu; Kareem Abu-Elmagd; Jorge Reyes; Ron Shapiro; Adriana Zeevi; Jan Mueller Berghaus; Lian Fu Wang; Lina Lu; Angus W Thomson; Walter J Storkus; John J Fung; Diana Metes
Augmentation of type-1 polarizing ability of monocyte-derived dendritic cells from chronically immunosuppressed organ-transplant recipients.
Transplantation 2005;79(4):451-9.
2005: Pawel Kalinski; Adam Giermasz; Yutaro Nakamura; Per H Basse; Walter J Storkus; John M Kirkwood; Robbie B Mailliard
Helper role of NK cells during the induction of anticancer responses by dendritic cells.
Molecular immunology 2005;42(4):535-9.
2005: Christopher J Herrem; Tomohide Tatsumi; Kathleen S Olson; Keisuke Shirai; James H Finke; Ronald M Bukowski; Ming Zhou; Amy L Richmond; Ithaar H Derweesh; Michael S Kinch; Walter J Storkus
Expression of EphA2 is prognostic of disease-free interval and overall survival in surgically treated patients with renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):226-31.
2004: Eva Pizzoferrato; Ye Liu; Andrea Gambotto; Michaele J Armstrong; Michael T Stang; William Gooding; Sean Alber; Stuart H Shand; simon simon watkins; Walter J Storkus; John H Yim
Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin.
Cancer research 2004;64(22):8381-8.
2004: Patricia Rayman; Amy Wesa; Amy L Richmond; Tanya Das; Kaushik Biswas; gira Raval; Walter J Storkus; Charles S Tannenbaum; Andrew C Novick; Ronald Bukowski; James Finke
Effect of renal cell carcinomas on the development of type 1 T-cell responses.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 2):6360S-6S.
2004: Robbie B Mailliard; Anna Wankowicz-Kalinska; Quan Cai; Amy Wesa; Catharien M Hilkens; Martien L Kapsenberg; John M Kirkwood; Walter J Storkus; Pawel Kalinski
alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity.
Cancer research 2004;64(17):5934-7.
2004: James H Finke; Charles S Tannenbaum; Walter J Storkus; Patricia Rayman; Tanya Das; Kaushik Biswas; Amy L Richmond; C Moon; Mark Thornton; I Gill; Andrew C Novick; Ronald Bukowski
Tumor-induced dysfunction in T lymphocytes: increased sensitivity to apoptosis.
Der Urologe. Ausg. A 2004;43 Suppl 3():S131-2.
2004: Hideho Okada; Takahiko Tsugawa; Hidemitsu Sato; Naruo Kuwashima; Andrea Gambotto; Kaori Okada; Jill E Dusak; Wendy Fellows-Mayle; Glenn D Papworth; simon simon watkins; William Chambers; Douglas M Potter; Walter J Storkus; Ian F Pollack
Delivery of interferon-alpha transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines.
Cancer research 2004;64(16):5830-8.
2004: Dominic E Warrino; Walter C Olson; William T Knapp; Meera I Scarrow; Lori J D'Ambrosio-Brennan; Richard S Guido; Robert P Edwards; W Martin Kast; Walter J Storkus
Disease-stage variance in functional CD4(+) T-cell responses against novel pan-human leukocyte antigen-D region presented human papillomavirus-16 E7 epitopes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3301-8.
2003: iulia popescu; Camila Macedo; Adriana Zeevi; Joseph Nellis; Kevin R Patterson; Alison J Logar; David Rowe; Jorge Reyes; Abdul S Rao; Walter J Storkus; John J Fung; Diana Metes
Ex vivo priming of naïve T cells into EBV-specific Th1/Tc1 effector cells by mature autologous DC loaded with apoptotic/necrotic LCL.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(11):1369-77.
2003: Tomohide Tatsumi; Jian Huang; William Gooding; Andrea Gambotto; Paul D Robbins; Nikola L Vujanovic; Sean Alber; simon simon watkins; Hideho Okada; Walter J Storkus
Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity.
Cancer research 2003;63(19):6378-86.
2003: Robbie B Mailliard; Young-Ik Son; Richard E Redlinger; P Toby H Coates; Adam Giermasz; Penelope A Morel; Walter J Storkus; Pawel Kalinski
Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2366-73.
2003: Tomohide Tatsumi; Christopher J Herrem; Walter C Olson; James H Finke; Ronald M Bukowski; Michael S Kinch; Elena Ranieri; Walter J Storkus
Disease stage variation in CD4+ and CD8+ T-cell reactivity to the receptor tyrosine kinase EphA2 in patients with renal cell carcinoma.
Cancer research 2003;63(15):4481-9.
2003: Norimoto Nakahara; Ian F Pollack; Walter J Storkus; Toshihiko Wakabayashi; Jun Yoshida; Hideho Okada
Effective induction of antiglioma cytotoxic T cells by coadministration of interferon-beta gene vector and dendritic cells.
Cancer gene therapy 2003;10(7):549-58.
2003: Anna Wankowicz-Kalinska; Caroline Le Poole; René M J G J van den Wijngaard; Walter J Storkus; Pranab K Das
Melanocyte-specific immune response in melanoma and vitiligo: two faces of the same coin?
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2003;16(3):254-60.
2003: Anna Wańkowicz-Kalińska; René M J G J van den Wijngaard; Bert J Tigges; Wiete Westerhof; Graham S Ogg; Vincenzo Cerundolo; Walter J Storkus; Pranab K Das
Immunopolarization of CD4+ and CD8+ T cells to Type-1-like is associated with melanocyte loss in human vitiligo.
Laboratory investigation; a journal of technical methods and pathology 2003;83(5):683-95.
2003: Tomohide Tatsumi; Lisa S Kierstead; Elena Ranieri; Loreto Gesualdo; Francesco Paolo Schena; James H Finke; Ronald M Bukowski; Vladimir Brusic; John Sidney; Alessandro Sette; Theodore F Logan; Yvette L Kasamon; Craig L Slingluff; John M Kirkwood; Walter J Storkus
MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):947-54.
2002: Tomohide Tatsumi; Walter J Storkus
Dendritic cell-based vaccines and therapies for cancer.
Expert opinion on biological therapy 2002;2(8):919-28.
2002: Tomohide Tatsumi; Andrea Gambotto; Paul D Robbins; Walter J Storkus
Interleukin 18 gene transfer expands the repertoire of antitumor Th1-type immunity elicited by dendritic cell-based vaccines in association with enhanced therapeutic efficacy.
Cancer research 2002;62(20):5853-8.
2002: Tomohide Tatsumi; Lisa S Kierstead; Elena Ranieri; Loreto Gesualdo; Francesco Paolo Schena; James H Finke; Ronald M Bukowski; Jan Muller-Berghaus; John M Kirkwood; William W Kwok; Walter J Storkus
Disease-associated bias in T helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401(+) patients with renal cell carcinoma or melanoma.
The Journal of experimental medicine 2002;196(5):619-28.
2002: Fumiyoshi Okano; Walter J Storkus; William Chambers; Ian F Pollack; Hideho Okada
Identification of a novel HLA-A*0201-restricted, cytotoxic T lymphocyte epitope in a human glioma-associated antigen, interleukin 13 receptor alpha2 chain.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2851-5.
2002: Anna Lokshin; Pawel Kalinski; R Rita Sassi; Robbie B Mailliard; Jan Muller-Berghaus; Walter J Storkus; Xiaojun Peng; Adele M Marrangoni; Robert P Edwards; Elieser Gorelik
Differential regulation of maturation and apoptosis of human monocyte-derived dendritic cells mediated by MHC class II.
International immunology 2002;14(9):1027-37.
2002: Pia Björck; Wen-Rong Lie; Susan L Woulfe; Barbara K Klein; Walter Olson; Walter J Storkus
Progenipoietin-generated dendritic cells exhibit anti-tumor efficacy in a therapeutic murine tumor model.
International journal of cancer. Journal international du cancer 2002;100(5):586-91.
2002: Thomas K Hoffmann; Jan Muller-Berghaus; Robert L Ferris; Jonas T Johnson; Walter J Storkus; Theresa L Whiteside
Alterations in the frequency of dendritic cell subsets in the peripheral circulation of patients with squamous cell carcinomas of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1787-93.
2002: Tadao Asai; Walter J Storkus; Jan Muller-Berghaus; William Knapp; Albert B DeLeo; Kazuaki Chikamatsu; Theresa L Whiteside
In vitro generated cytolytic T lymphocytes reactive against head and neck cancer recognize multiple epitopes presented by HLA-A2, including peptides derived from the p53 and MDM-2 proteins.
Cancer immunity 2002;2():3.
2002: Jaafar Bennouna; Allan Hildesheim; Kazuaki Chikamatsu; William Gooding; Walter J Storkus; Theresa L Whiteside
Application of IL-5 ELISPOT assays to quantification of antigen-specific T helper responses.
Journal of immunological methods 2002;261(1-2):145-56.
2002: Robbie B Mailliard; Shinichi Egawa; Quan Cai; Anna Kalinska; Svetlana N Bykovskaya; Michael T Lotze; Martien L Kapsenberg; Walter J Storkus; Pawel Kalinski
Complementary dendritic cell-activating function of CD8+ and CD4+ T cells: helper role of CD8+ T cells in the development of T helper type 1 responses.
The Journal of experimental medicine 2002;195(4):473-83.
2002: Ganwei Lu; Bratislav Janjic; Jelena M Janjic; Theresa L Whiteside; Walter J Storkus; Nikola L Vujanovic
Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1831-9.
2002: Bratislav Janjic; Ganwei Lu; Alexei Pimenov; Theresa L Whiteside; Walter J Storkus; Nikola L Vujanovic
Innate direct anticancer effector function of human immature dendritic cells. I. Involvement of an apoptosis-inducing pathway.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1823-30.
2002: Svetlana N Bykovskaia; Galina V Shurin; Scott Graner; Mark L Bunker; Walter Olson; Ronald Thomas; Michael R Shurin; Stanley Marks; Walter J Storkus; Jeffrey Shogan
Differentiation of immunostimulatory stem-cell- and monocyte-derived dendritic cells involves maturation of intracellular compartments responsible for antigen presentation and secretion.
Stem cells (Dayton, Ohio) 2002;20(5):380-93.
2001: Lisa S Kierstead; Elena Ranieri; Walter Olson; Vladimir Brusic; John Sidney; Alessandro Sette; Yvette L Kasamon; Craig L Slingluff; John M Kirkwood; Walter J Storkus
gp100/pmel17 and tyrosinase encode multiple epitopes recognized by Th1-type CD4+T cells.
British journal of cancer 2001;85(11):1738-45.
2001: Adriana T Larregina; simon simon watkins; Geza Erdos; L A Spencer; Walter J Storkus; Donna Beer-Stolz; Louis Falo
Direct transfection and activation of human cutaneous dendritic cells.
Gene therapy 2001;8(8):608-17.
2001: Thomas K Hoffmann; Norbert Meidenbauer; Jan Muller-Berghaus; Walter J Storkus; Theresa L Whiteside
Proinflammatory cytokines and CD40 ligand enhance cross-presentation and cross-priming capability of human dendritic cells internalizing apoptotic cancer cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2001;24(2):162-71.
2001: Diana Metes; Walter J Storkus; Adriana Zeevi; S Watkins; K Patterson; Joseph Nellis; Alison J Logar; John J Fung; Abdul S Rao
Use of autologous dendritic cells loaded with apoptotic LCL for ex vivo generation of specific CTL from the PBMC of EBV(-) individuals.
Transplantation proceedings 2001;33(1-2):441.
2000: Diana Metes; Walter J Storkus; Adriana Zeevi; K Patterson; Alison J Logar; David Rowe; Michael A Nalesnik; John J Fung; Abdul S Rao
Ex vivo generation of effective Epstein-Barr virus (EBV)-specific CD8+ cytotoxic T lymphocytes from the peripheral blood of immunocompetent Epstein Barr virus-seronegative individuals.
Transplantation 2000;70(10):1507-15.
2000: Hassane M Zarour; Walter J Storkus; Vladimir Brusic; E Williams; John M Kirkwood
NY-ESO-1 encodes DRB1*0401-restricted epitopes recognized by melanoma-reactive CD4+ T cells.
Cancer research 2000;60(17):4946-52.
2000: W Herr; Elena Ranieri; Walter Olson; Hassane M Zarour; Loreto Gesualdo; Walter J Storkus
Mature dendritic cells pulsed with freeze-thaw cell lysates define an effective in vitro vaccine designed to elicit EBV-specific CD4(+) and CD8(+) T lymphocyte responses.
Blood 2000;96(5):1857-64.
2000: Walter J Storkus; Hassane M Zarour
Melanoma antigens recognised by CD8+ and CD4+ T cells.
Forum (Genoa, Italy) 2000;10(3):256-70.
2000: Elena Ranieri; Lisa S Kierstead; Hassane M Zarour; John M Kirkwood; Michael T Lotze; Theresa L Whiteside; Walter J Storkus
Dendritic cell/peptide cancer vaccines: clinical responsiveness and epitope spreading.
Immunological investigations 2000;29(2):121-5.
2000: T Asai; Walter J Storkus; Theresa L Whiteside
Evaluation of the modified ELISPOT assay for gamma interferon production in cancer patients receiving antitumor vaccines.
Clinical and diagnostic laboratory immunology 2000;7(2):145-54.
2000: Michael T Lotze; Michael R Shurin; Clemens Esche; Hideaki Tahara; Walter J Storkus; John M Kirkwood; Theresa L Whiteside; Elaine Elder; H Okada; Paul D Robbins
Interleukin-2: developing additional cytokine gene therapies using fibroblasts or dendritic cells to enhance tumor immunity.
The cancer journal from Scientific American 2000;6 Suppl 1():S61-6.
2000: Hassane M Zarour; John M Kirkwood; Lisa S Kierstead; W Herr; Vladimir Brusic; Craig L Slingluff; John Sidney; Alessandro Sette; Walter J Storkus
Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):400-5.
2000: Thomas Tüting; J Austyn; Walter J Storkus; Louis Falo
The immunology of DNA vaccines.
Methods in molecular medicine 2000;29():37-64.
2000: Xin Dong; B An; L Salvucci Kierstead; Walter J Storkus; Andrew A Amoscato; Russell D Salter
Modification of the amino terminus of a class II epitope confers resistance to degradation by CD13 on dendritic cells and enhances presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):129-35.
1999: Elena Ranieri; W Herr; Andrea Gambotto; Walter Olson; D Rowe; P D Robbins; Lisa S Kierstead; simon simon watkins; Loreto Gesualdo; Walter J Storkus
Dendritic cells transduced with an adenovirus vector encoding Epstein-Barr virus latent membrane protein 2B: a new modality for vaccination.
Journal of virology 1999;73(12):10416-25.
1999: Xin Dong; Walter J Storkus; Russell D Salter
Binding and uptake of agalactosyl IgG by mannose receptor on macrophages and dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5427-34.
1999: W Herr; Elena Ranieri; Andrea Gambotto; Lisa S Kierstead; Andrew A Amoscato; Loreto Gesualdo; Walter J Storkus
Identification of naturally processed and HLA-presented Epstein-Barr virus peptides recognized by CD4(+) or CD8(+) T lymphocytes from human blood.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):12033-8.
1999: Kazuaki Chikamatsu; Koji Nakano; Walter J Storkus; Ettore Appella; Michael T Lotze; Theresa L Whiteside; Albert B DeLeo
Generation of anti-p53 cytotoxic T lymphocytes from human peripheral blood using autologous dendritic cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(6):1281-8.
1999: Thomas Tüting; Andrea Gambotto; Paul D Robbins; Walter J Storkus; Albert B DeLeo
Co-delivery of T helper 1-biasing cytokine genes enhances the efficacy of gene gun immunization of mice: studies with the model tumor antigen beta-galactosidase and the BALB/c Meth A p53 tumor-specific antigen.
Gene therapy 1999;6(4):629-36.
1999: CC Wilson; Walter C Olson; T Tuting; Charles Rinaldo; Michael T Lotze; Walter J Storkus
HIV-1-specific CTL responses primed in vitro by blood-derived dendritic cells and Th1-biasing cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(5):3070-8.
1999: Thomas Tüting; Andrea Gambotto; Albert B DeLeo; Michael T Lotze; Paul D Robbins; Walter J Storkus
Induction of tumor antigen-specific immunity using plasmid DNA immunization in mice.
Cancer gene therapy 1999;6(1):73-80.
1998: Louis Falo; Walter J Storkus
Giving DNA vaccines a helping hand.
Nature medicine 1998;4(11):1239-40.
1998: Tjendimin Tjandrawan; D M Martin; Markus J Maeurer; Chiara Castelli; Michael T Lotze; Walter J Storkus
Autologous human dendriphages pulsed with synthetic or natural tumor peptides elicit tumor-specific CTLs in vitro.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1998;21(2):149-57.
1998: Thomas Tüting; CC Wilson; D M Martin; Yvette L Kasamon; Jennifer L Rowles; D I Ma; Craig L Slingluff; S N Wagner; P van der Bruggen; Joseph Baar; Michael T Lotze; Walter J Storkus
Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1139-47.
1998: Thomas Tüting; CC Wilson; D M Martin; Joseph Baar; Albert B DeLeo; Michael T Lotze; Walter J Storkus
DNA vaccines targeting dendritic cells for the immunotherapy of cancer.
Advances in experimental medicine and biology 1998;451():295-304.
1997: Michael T Lotze; B Hellerstedt; L Stolinski; T Tueting; C Wilson; D Kinzler; H Vu; Joshua Rubin; Walter J Storkus; Hideaki Tahara; Elaine Elder; Theresa L Whiteside
The role of interleukin-2, interleukin-12, and dendritic cells in cancer therapy.
The cancer journal from Scientific American 1997;3 Suppl 1():S109-14.
1997: Thomas Tüting; Andrea Gambotto; Joseph Baar; I D Davis; Walter J Storkus; Paul J Zavodny; Satwant K Narula; Hideaki Tahara; Paul D Robbins; Michael T Lotze
Interferon-alpha gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models.
Gene therapy 1997;4(10):1053-60.
1997: Thomas Tüting; Albert B DeLeo; Michael T Lotze; Walter J Storkus
Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or "self" antigens induce antitumor immunity in vivo.
European journal of immunology 1997;27(10):2702-7.
1997: Michael R Shurin; P P Pandharipande; tatiana Zorina; Catherine Haluszczak; Vladimir M Subbotin; Oriana C Hunter; AM Brumfield; Walter J Storkus; E Maraskovsky; Michael T Lotze
FLT3 ligand induces the generation of functionally active dendritic cells in mice.
Cellular immunology 1997;179(2):174-84.
1997: Thomas Tüting; Walter J Storkus; Michael T Lotze
Gene-based strategies for the immunotherapy of cancer.
Journal of molecular medicine (Berlin, Germany) 1997;75(7):478-91.
1997: Markus J Maeurer; Wolfgang Walter; D Martin; L Zitvogel; Elaine Elder; Walter J Storkus; Michael T Lotze
Interleukin-7 (IL-7) in colorectal cancer: IL-7 is produced by tissues from colorectal cancer and promotes preferential expansion of tumour infiltrating lymphocytes.
Scandinavian journal of immunology 1997;45(2):182-92.
1997: Michael T Lotze; Michael R Shurin; I Davis; Andrew A Amoscato; Walter J Storkus
Dendritic cell based therapy of cancer.
Advances in experimental medicine and biology 1997;417():551-69.
1997: Thomas Tüting; tatiana Zorina; D I Ma; CC Wilson; C M De Cesare; Albert B De Leo; Michael T Lotze; Walter J Storkus
Development of dendritic cell-based genetic vaccines for cancer.
Advances in experimental medicine and biology 1997;417():511-8.
1997: CC Wilson; T Tueting; D Ma; Catherine Haluszczak; M Lotze; Walter J Storkus
Activation of dendritic cells by surrogate T cell interactions leads to enhanced costimulation, secretion of TH1-associated cytokines, and CTL inductive capacity.
Advances in experimental medicine and biology 1997;417():335-43.
1997: José I Mayordomo; tatiana Zorina; Walter J Storkus; L Zitvogel; Maria Dolores Garcia-Prats; Albert B DeLeo; Michael T Lotze
Bone marrow-derived dendritic cells serve as potent adjuvants for peptide-based antitumor vaccines.
Stem cells (Dayton, Ohio) 1997;15(2):94-103.
1996: Markus J Maeurer; H W Chan; Julia Karbach; Russell D Salter; Alexander Knuth; Michael T Lotze; Walter J Storkus
Amino acid substitutions at position 97 in HLA-A2 segregate cytolysis from cytokine release in MART-1/Melan-A peptide AAGIGILTV-specific cytotoxic T lymphocytes.
European journal of immunology 1996;26(11):2613-23.
1996: Michael T Lotze; L Zitvogel; R Campbell; Paul D Robbins; Elaine Elder; Catherine Haluszczak; D Martin; Theresa L Whiteside; Walter J Storkus; Hideaki Tahara
Cytokine gene therapy of cancer using interleukin-12: murine and clinical trials.
Annals of the New York Academy of Sciences 1996;795():440-54.
1996: L Zitvogel; Bettina Couderc; José I Mayordomo; Paul D Robbins; Michael T Lotze; Walter J Storkus
IL-12-engineered dendritic cells serve as effective tumor vaccine adjuvants in vivo.
Annals of the New York Academy of Sciences 1996;795():284-93.
1996: Hideaki Tahara; L Zitvogel; Walter J Storkus; Paul D Robbins; Michael T Lotze
Murine models of cancer cytokine gene therapy using interleukin-12.
Annals of the New York Academy of Sciences 1996;795():275-83.
1996: Markus J Maeurer; Susanne M Gollin; D Martin; William P Swaney; J Bryant; Chiara Castelli; Paul Robbins; G Parmiani; Walter J Storkus; Michael T Lotze
Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.
The Journal of clinical investigation 1996;98(7):1633-41.
1996: Arabella Mazzocchi; Walter J Storkus; Catia Traversari; P Tarsini; Markus J Maeurer; Licia Rivoltini; C Vegetti; Filiberto Belli; Andrea Anichini; Giorgio Parmiani; Chiara Castelli
Multiple melanoma-associated epitopes recognized by HLA-A3-restricted CTLs and shared by melanomas but not melanocytes.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):3030-8.
1996: L Zitvogel; Paul D Robbins; Walter J Storkus; MR Clarke; Markus J Maeurer; R L Campbell; C G Davis; Hideaki Tahara; R D Schreiber; Michael T Lotze
Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors.
European journal of immunology 1996;26(6):1335-41.
1996: Markus J Maeurer; Susanne M Gollin; Walter J Storkus; William P Swaney; Julia Karbach; D Martin; Chiara Castelli; R Salter; Alexander Knuth; Michael T Lotze
Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(4):641-52.
1996: Markus J Maeurer; D Martin; Wolfgang Walter; K Liu; L Zitvogel; K Halusczcak; Hannah Rabinowich; R Duquesnoy; Walter J Storkus; Michael T Lotze
Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin.
The Journal of experimental medicine 1996;183(4):1681-96.
1996: José I Mayordomo; D J Loftus; H Sakamoto; C M De Cesare; PM Appasamy; Michael T Lotze; Walter J Storkus; Ettore Appella; Albert B DeLeo
Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines.
The Journal of experimental medicine 1996;183(4):1357-65.
1996: Markus J Maeurer; Walter J Storkus; John M Kirkwood; Michael T Lotze
New treatment options for patients with melanoma: review of melanoma-derived T-cell epitope-based peptide vaccines.
Melanoma research 1996;6(1):11-24.
1996: Walter J Storkus; M Wei; Peter Cresswell; Jeffrey R Dawson
Class I-like CD1A-C do not protect target cells from NK-mediated cytolysis.
Cellular immunology 1996;167(1):154-6.
1996: Markus J Maeurer; D Martin; Elaine Elder; Walter J Storkus; Michael T Lotze
Detection of naturally processed and HLA-A1-presented melanoma T-cell epitopes defined by CD8(+) T-cells' release of granulocyte-macrophage colony-stimulating factor but not by cytolysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(1):87-95.
1996: L Zitvogel; José I Mayordomo; T Tjandrawan; Albert B DeLeo; MR Clarke; Michael T Lotze; Walter J Storkus
Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.
The Journal of experimental medicine 1996;183(1):87-97.
1996: Christina Celluzzi; José I Mayordomo; Walter J Storkus; Michael T Lotze; Louis Falo
Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.
The Journal of experimental medicine 1996;183(1):283-7.
1995: Hideaki Tahara; Michael T Lotze; Paul D Robbins; Walter J Storkus; L Zitvogel
IL-12 gene therapy using direct injection of tumors with genetically engineered autologous fibroblasts.
Human gene therapy 1995;6(12):1607-24.
1995: Markus J Maeurer; D M Martin; Walter J Storkus; M T Lotze
TCR usage in CTLs recognizing melanoma/melanocyte antigens.
Immunology today 1995;16(12):603-4.
1995: José I Mayordomo; tatiana Zorina; Walter J Storkus; L Zitvogel; C Celluzzi; Louis Falo; C J Melief; Suzanne Ildstad; W M Kast; Albert B DeLeo
Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity.
Nature medicine 1995;1(12):1297-302.
1995: Markus J Maeurer; D M Martin; Chiara Castelli; Elaine Elder; G Leder; Walter J Storkus; Michael T Lotze
Host immune response in renal cell cancer: interleukin-4 (IL-4) and IL-10 mRNA are frequently detected in freshly collected tumor-infiltrating lymphocytes.
Cancer immunology, immunotherapy : CII 1995;41(2):111-21.
1995: L Zitvogel; Hideaki Tahara; Paul D Robbins; Walter J Storkus; MR Clarke; M A Nalesnik; Michael T Lotze
Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1393-403.
1995: Markus J Maeurer; S Hurd; D M Martin; Walter J Storkus; Michael T Lotze
Cytolytic T-cell clones define HLA-A2-restricted human cutaneous melanoma peptide epitopes: correlation with T-cell receptor usage.
The cancer journal from Scientific American 1995;1(2):162-70.
1995: Hideaki Tahara; L Zitvogel; Walter J Storkus; H J Zeh; T G McKinney; R D Schreiber; U Gubler; Paul D Robbins; Michael T Lotze
Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6466-74.
1995: Markus J Maeurer; L Zitvogel; Elaine Elder; Walter J Storkus; Michael T Lotze
Human intestinal V delta 1+ T cells obtained from patients with colon cancer respond exclusively to SEB but not to SEA.
Natural immunity 1995;14(4):188-97.
1995: Chiara Castelli; Walter J Storkus; Markus J Maeurer; D M Martin; E C Huang; B N Pramanik; TL Nagabhushan; Giorgio Parmiani; Michael T Lotze
Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes.
The Journal of experimental medicine 1995;181(1):363-8.
1995: M A Frassanito; José I Mayordomo; R M DeLeo; Walter J Storkus; Michael T Lotze; Albert B DeLeo
Identification of Meth A sarcoma-derived class I major histocompatibility complex-associated peptides recognized by a specific CD8+ cytotoxic T lymphocyte.
Cancer research 1995;55(1):124-8.
1994: L Zitvogel; Hideaki Tahara; Q Cai; Walter J Storkus; G Muller; Stanley Wolf; M Gately; Paul D Robbins; Michael T Lotze
Construction and characterization of retroviral vectors expressing biologically active human interleukin-12.
Human gene therapy 1994;5(12):1493-506.
1994: C L Nastala; Howard D Edington; T G McKinney; Hideaki Tahara; M A Nalesnik; M J Brunda; M K Gately; Stanley Wolf; R D Schreiber; Walter J Storkus
Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(4):1697-706.
1994: T Itoh; Walter J Storkus; Elieser Gorelik; Michael T Lotze
Partial purification of murine tumor-associated peptide epitopes common to histologically distinct tumors, melanoma and sarcoma, that are presented by H-2Kb molecules and recognized by CD8+ tumor-infiltrating lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(3):1202-15.
1994: H J Zeh; G H Leder; Michael T Lotze; Russell D Salter; M Tector; G Stuber; Susanne Modrow; Walter J Storkus
Flow-cytometric determination of peptide-class I complex formation. Identification of p53 peptides that bind to HLA-A2.
Human immunology 1994;39(2):79-86.
1994: Hideaki Tahara; H J Zeh; Walter J Storkus; I Pappo; simon simon watkins; U Gubler; Stanley Wolf; Paul D Robbins; Michael T Lotze
Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.
Cancer research 1994;54(1):182-9.
1993: Walter J Storkus; H J Zeh; Markus J Maeurer; Russell D Salter; Michael T Lotze
Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3719-27.
1993: H J Zeh; S Hurd; Walter J Storkus; Michael T Lotze
Interleukin-12 promotes the proliferation and cytolytic maturation of immune effectors: implications for the immunotherapy of cancer.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(2):155-61.
1993: Walter J Storkus; H J Zeh; Russell D Salter; Michael T Lotze
Identification of T-cell epitopes: rapid isolation of class I-presented peptides from viable cells by mild acid elution.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1993;14(2):94-103.
1992: Walter J Storkus; Russell D Salter; Peter Cresswell; Jeffrey R Dawson
Peptide-induced modulation of target cell sensitivity to natural killing.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1185-90.
1991: Walter J Storkus; Russell D Salter; J Alexander; FE Ward; R E Ruiz; Peter Cresswell; Jeffrey R Dawson
Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):5989-92.
1990: M F Miller; Thomas G Mitchell; Walter J Storkus; Jeffrey R Dawson
Human natural killer cells do not inhibit growth of Cryptococcus neoformans in the absence of antibody.
Infection and immunity 1990;58(3):639-45.
1989: Walter J Storkus; J Alexander; John A Payne; Peter Cresswell; Jeffrey R Dawson
The alpha 1/alpha 2 domains of class I HLA molecules confer resistance to natural killing.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3853-7.
1989: Walter J Storkus; J Alexander; John A Payne; Jeffrey R Dawson; Peter Cresswell
Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2361-4.
1987: Walter J Storkus; D N Howell; Russell D Salter; Jeffrey R Dawson; Peter Cresswell
NK susceptibility varies inversely with target cell class I HLA antigen expression.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(6):1657-9.