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Elizabeth Stover

Research Profile

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Inga Hofmann; Elizabeth H Stover; Dana E Cullen; Junhao Mao; Kelly J Morgan; Benjamin H Lee; Michael G Kharas; Peter G Miller; Melanie G Cornejo; Rachel Okabe; Scott A Armstrong; Nico Ghilardi; Stephen Gould; Frederic J de Sauvage; Andrew P McMahon; D Gary Gilliland
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.
Els Lierman; Cedric Folens; Elizabeth H Stover; Nicole Mentens; Helen Van Miegroet; Werner Scheers; Marc Boogaerts; Peter Vandenberghe; Peter Marynen; Jan Cools
Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.
Elizabeth H Stover; Jing Chen; Cedric Folens; Benjamin H Lee; Nicole Mentens; Peter Marynen; Ifor Williams; D Gary Gilliland; Jan Cools
Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.

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All Publications

2009: Inga Hofmann; Elizabeth H Stover; Dana E Cullen; Junhao Mao; Kelly J Morgan; Benjamin H Lee; Michael G Kharas; Peter G Miller; Melanie G Cornejo; Rachel Okabe; Scott A Armstrong; Nico Ghilardi; Stephen Gould; Frederic J de Sauvage; Andrew P McMahon; D Gary Gilliland
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.
Cell stem cell 2009;4(6):559-67.
2006: Els Lierman; Cedric Folens; Elizabeth H Stover; Nicole Mentens; Helen Van Miegroet; Werner Scheers; Marc Boogaerts; Peter Vandenberghe; Peter Marynen; Jan Cools
Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.
Blood 2006;108(4):1374-6.
2006: Elizabeth H Stover; Jing Chen; Cedric Folens; Benjamin H Lee; Nicole Mentens; Peter Marynen; Ifor Williams; D Gary Gilliland; Jan Cools
Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8078-83.
2006: Jan Cools; Elizabeth H Stover; D Gary Gilliland
Detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia.
Methods in molecular medicine 2006;125():177-87.
2005: Elizabeth H Stover; Jing Chen; Benjamin H Lee; Jan Cools; Elizabeth P McDowell; Jennifer Adelsperger; Dana Cullen; Allison Coburn; Sandra A Moore; Rachel Okabe; Doriano Fabbro; Paul W Manley; James D Griffin; D Gary Gilliland
The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo.
Blood 2005;106(9):3206-13.
2004: Gary Gilliland; Jan Cools; Elizabeth H Stover; Iwona Wlodarska; Peter Marynen
FIP1L1-PDGFRalpha in hypereosinophilic syndrome and mastocytosis.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5 Suppl 3():S133-7.
2004: Jan Cools; Elizabeth H Stover; Iwona Wlodarska; Peter Marynen; D Gary Gilliland
The FIP1L1-PDGFRalpha kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia.
Current opinion in hematology 2004;11(1):51-7.
2003: Jan Cools; Elizabeth H Stover; Christina L Boulton; Jason Gotlib; Robert D Legare; Sonia M Amaral; David P Curley; Nicole Duclos; Rebecca Rowan; Jeffery L Kutok; Benjamin H Lee; Ifor Williams; Steven E Coutre; Richard M Stone; Daniel J DeAngelo; Peter Marynen; Paul W Manley; Thomas Meyer; Doriano Fabbro; Donna Neuberg; Ellen Weisberg; James D Griffin; D Gary Gilliland
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.
Cancer cell 2003;3(5):459-69.
2003: Jan Cools; Daniel J DeAngelo; Jason Gotlib; Elizabeth H Stover; Robert D Legare; Jorges Cortes; Jeffery L Kutok; Jennifer Clark; Ilene Galinsky; James D Griffin; Nicholas C P Cross; Ayalew Tefferi; James Malone; Rafeul Alam; Stanley L Schrier; Janet Schmid; Michal Rose; Peter Vandenberghe; Gregor Verhoef; Marc Boogaerts; Iwona Wlodarska; Andrew Lamb; Peter Marynen; Steven E Coutre; Richard M Stone; D Gary Gilliland
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
The New England journal of medicine 2003;348(13):1201-14.