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Michael Streit

Research Profile

Disorders

Living Beings

Physiology

Chemicals & Drugs

Anatomy

Tumor Cells, Cultured

Procedures

Neoplasm Transplantation

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Publications

TOP 3
Karen O Yee; Michael Streit; Thomas Hawighorst; Michael Detmar; Jack Lawler
Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta.
Yun-Hee Noh; Kant Matsuda; Young Kwon Hong; Rainer Kunstfeld; Lucia Riccardi; Manuel Koch; Hajimu Oura; Soheil S Dadras; Michael Streit; Michael Detmar
An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivo.
Thomas Hawighorst; Hajimu Oura; Michael Streit; Lauren Janes; Lynh Nguyen; Lawrence F Brown; Guillermo Oliver; David G Jackson; Michael Detmar
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice.

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All Publications

2004: Karen O Yee; Michael Streit; Thomas Hawighorst; Michael Detmar; Jack Lawler
Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta.
The American journal of pathology 2004;165(2):541-52.
2003: Yun-Hee Noh; Kant Matsuda; Young Kwon Hong; Rainer Kunstfeld; Lucia Riccardi; Manuel Koch; Hajimu Oura; Soheil S Dadras; Michael Streit; Michael Detmar
An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivo.
The Journal of investigative dermatology 2003;121(6):1536-43.
2002: Thomas Hawighorst; Hajimu Oura; Michael Streit; Lauren Janes; Lynh Nguyen; Lawrence F Brown; Guillermo Oliver; David G Jackson; Michael Detmar
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice.
Oncogene 2002;21(52):7945-56.
2002: Thomas Hawighorst; Mihaela Skobe; Michael Streit; Young Kwon Hong; Paula Velasco; Lawrence F Brown; Lucia Riccardi; Bernhard Lange-Asschenfeldt; Michael Detmar
Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth.
The American journal of pathology 2002;160(4):1381-92.
2002: Michael Streit; Antonia E Stephen; Thomas Hawighorst; Kant Matsuda; Bernhard Lange-Asschenfeldt; Lawrence F Brown; Joseph P Vacanti; Michael Detmar
Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.
Cancer research 2002;62(7):2004-12.
2002: Donald R Senger; Carole A Perruzzi; Michael Streit; Victor E Koteliansky; Antonin R de Fougerolles; Michael Detmar
The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis.
The American journal of pathology 2002;160(1):195-204.
2001: Bernhard Lange-Asschenfeldt; Paula Velasco; Michael Streit; Thomas Hawighorst; Sandra E Pike; Giovanna Tosato; Michael Detmar
The angiogenesis inhibitor vasostatin does not impair wound healing at tumor-inhibiting doses.
The Journal of investigative dermatology 2001;117(5):1036-41.
2001: Thomas Hawighorst; Paula Velasco; Michael Streit; Young Kwon Hong; Themis R Kyriakides; Lawrence F Brown; Paul Bornstein; Michael Detmar
Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism.
The EMBO journal 2001;20(11):2631-40.
2000: Michael Streit; Paula Velasco; Lucia Riccardi; L Spencer; Lawrence F Brown; Lauren Janes; Bernhard Lange-Asschenfeldt; Kiichiro Yano; Thomas Hawighorst; L Iruela-Arispe; Michael Detmar
Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice.
The EMBO journal 2000;19(13):3272-82.
2000: Michael Detmar; Paula Velasco; L Richard; Kevin P Claffey; Michael Streit; Lucia Riccardi; Mihaela Skobe; Lawrence F Brown
Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas.
The American journal of pathology 2000;156(1):159-67.
1999: Michael Streit; Lucia Riccardi; Paula Velasco; Lawrence F Brown; Thomas Hawighorst; Paul Bornstein; Michael Detmar
Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14888-93.
1999: Michael Streit; Paula Velasco; Lawrence F Brown; Mihaela Skobe; L Richard; Lucia Riccardi; Jack Lawler; Michael Detmar
Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas.
The American journal of pathology 1999;155(2):441-52.