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Miroslav Strnad

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Marek Zatloukal; Eva Řezníčková; Jiří Voller; Helena Adamcová; Tomáš Gucký; Radek Jorda; Vladimír Kryštof; Veronika Malínková; Tomáš Pospíšil; Miroslav Strnad
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.
Adeyemi O Aremu; Michael W Bairu; Karel Doležal; Jeffrey F Finnie; Ondrej Novák; Lenka Plačková; Miroslav Strnad; Marek Zatloukal; Johannes Van Staden
Physiological responses and endogenous cytokinin profiles of tissue-cultured 'Williams' bananas in relation to roscovitine and an inhibitor of cytokinin oxidase/dehydrogenase (INCYDE) treatments.
Tibor Béres; Marco A Dessoy; David Friedecký; Markus Ganzera; Markéta Gemrotová; Vítězslav Maier; Lukás Spíchal; Miroslav Strnad; Petr Tarkowski; Ludger A Wessjohann; Karel Doležal
Analysis of cytokinin nucleotides by capillary zone electrophoresis with diode array and mass spectrometric detection in a recombinant enzyme in vitro reaction.

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2013: Marek Zatloukal; Eva Řezníčková; Jiří Voller; Helena Adamcová; Tomáš Gucký; Radek Jorda; Vladimír Kryštof; Veronika Malínková; Tomáš Pospíšil; Miroslav Strnad
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases.
European journal of medicinal chemistry 2013;61():61-72.
2012: Adeyemi O Aremu; Michael W Bairu; Karel Doležal; Jeffrey F Finnie; Ondrej Novák; Lenka Plačková; Miroslav Strnad; Marek Zatloukal; Johannes Van Staden
Physiological responses and endogenous cytokinin profiles of tissue-cultured 'Williams' bananas in relation to roscovitine and an inhibitor of cytokinin oxidase/dehydrogenase (INCYDE) treatments.
Planta 2012;236(6):1775-90.
2012: Tibor Béres; Marco A Dessoy; David Friedecký; Markus Ganzera; Markéta Gemrotová; Vítězslav Maier; Lukás Spíchal; Miroslav Strnad; Petr Tarkowski; Ludger A Wessjohann; Karel Doležal
Analysis of cytokinin nucleotides by capillary zone electrophoresis with diode array and mass spectrometric detection in a recombinant enzyme in vitro reaction.
Analytica chimica acta 2012;751():176-81.
2012: Lucie Rárová; David Sedlák; Stefan Zahler; Petr Bartůněk; Ladislav Kohout; Vladimír Kryštof; Johanna Liebl; Miroslav Strnad
Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells.
Steroids 2012;77(13):1502-9.
2012: Jana Steigerová; Michaela Sváchová; Zdeněk Kolář; Kateřina Křížová; Monika Levková; Jana Oklešt'ková; Lucie Rárová; Miroslav Strnad
Mechanisms of natural brassinosteroid-induced apoptosis of prostate cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(11):4068-76.
2012: Jerald J Nair; Lucie Rárová; Miroslav Strnad; Jaume Bastida; Johannes Van Staden
Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
Bioorganic & medicinal chemistry letters 2012;22(19):6195-9.
2012: Hanna Richter; Miroslav Strnad; Jiri Gruz; Reinhard Lieberei; Ondrej Novák; Stefan A Rensing; Klaus von Schwartzenberg
Polyphenol oxidases in Physcomitrella: functional PPO1 knockout modulates cytokinin-dependent development in the moss Physcomitrella patens.
Journal of experimental botany 2012;63(14):5121-35.
2012: Antje Voegele; Veronika Turečková; Kai Graeber; Dominique Jacquemoud; Krystyna Oracz; Miroslav Strnad; Danuše Tarkowská; Terezie Urbanová; Gerhard Leubner-Metzger
Embryo growth, testa permeability, and endosperm weakening are major targets for the environmentally regulated inhibition of Lepidium sativum seed germination by myrigalone A.
Journal of experimental botany 2012;63(14):5337-50.
2012: Iva Dolečková; Jiří Grúz; Lucie Rárová; Miroslav Strnad; Magdaléna Vondrusová; Vladimír Kryštof
Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves.
Fitoterapia 2012;83(6):1000-7.
2012: Niloufer G Irani; Ladislav Kohout; Annemieke Madder; Kiril Mishev; Evelien Mylle; Dieter Buyst; Ana I Caño-Delgado; Mirela-Corina Codreanu; Simone Di Rubbo; Jirí Friml; Jaroslava Hniliková; Joanna Schneider-Pizoń; Miroslav Strnad; Anna-Mária Szatmári; Daniël Van Damme; Jos Van den Begin; Josep Vilarrasa-Blasi; Miroslav Šíša; Eugenia Russinova
Fluorescent castasterone reveals BRI1 signaling from the plasma membrane.
Nature chemical biology 2012;8(6):583-9.
2012: Wendy A Stirk; Miroslav Strnad; Václav Motyka; Ondrej Novák; Eva Zižková; Johannes Van Staden
Comparison of endogenous cytokinins and cytokinin oxidase/dehydrogenase activity in germinating and thermoinhibited Tagetes minuta achenes.
Journal of plant physiology 2012;169(7):696-703.
2012: Danuše Tarkowská; Jolanta Biesaga-Kościelniak; Maria Filek; Jan Krekule; Ivana Macháčková; Izabela Marcińska; Miroslav Strnad
Cytokinins in shoot apices of Brassica napus plants during vernalization.
Plant science : an international journal of experimental plant biology 2012;187():105-12.
2012: Kateřina Podlešáková; Lukás Spíchal; Miroslav Strnad; Lucie Szüčová; David Zalabák; Mária Cudejková; Karel Doležal; Ondřej Plíhal; Petr Galuszka
Novel cytokinin derivatives do not show negative effects on root growth and proliferation in submicromolar range.
PloS one 2012;7(6):e39293.
2012: Jana Svačinová; Josef Holík; René Lenobel; Ondrej Novák; Lenka Plačková; Miroslav Strnad; Karel Doležal
A new approach for cytokinin isolation from Arabidopsis tissues using miniaturized purification: pipette tip solid-phase extraction.
Plant methods 2012;8(1):17.
2012: Keqing Wang; Paul Pechan; Miroslav Strnad; Peter Hampson; Jon Hazeldine; Vladimír Krystof; Janet M
Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis.
PloS one 2012;7(1):e30128.
2011: Václav Mik; Jaroslav Nisler; Ondřej Plíhal; Lukás Spíchal; Lucie Szüčová; Lenka Zahajská; Karel Doležal; Miroslav Strnad
N9-Substituted N⁶-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays.
Bioorganic & medicinal chemistry 2011;19(23):7244-51.
2011: Michal Siller; Pavel Anzenbacher; Eva Anzenbacherová; Karel Doležal; Miroslav Strnad
In vitro interaction of a novel neutrophil growth factor with human liver microsomal cytochromes P450 and the contribution of UDP-glucuronosyltransferases to its metabolism.
Xenobiotica; the fate of foreign compounds in biological systems 2011;41(11):934-44.
2011: Radek Jorda; Kateřina Kráčalíková; Vladimír Kryštof; Abedelmajeed Nasereddin; Matthew W Nowicki; Nina Sacerdoti-Sierra; Miroslav Strnad; Jiří Voller; Malcolm D Walkinshaw; Libor Havlíček; Charles L Jaffe
Anti-leishmanial activity of disubstituted purines and related pyrazolo[4,3-d]pyrimidines.
Bioorganic & medicinal chemistry letters 2011;21(14):4233-7.
2011: Václav Mik; Lucie Szüčová; Mária Smehilová; Marek Zatloukal; Karel Doležal; Jaroslav Nisler; Jiří Grúz; Petr Galuszka; Miroslav Strnad; Lukás Spíchal
N9-substituted derivatives of kinetin: effective anti-senescence agents.
Phytochemistry 2011;72(8):821-31.
2011: Jadwiga Maj; Jacek W Morzycki; Jana Oklest'ková; Lucie Rárová; Miroslav Strnad; Agnieszka Wojtkielewicz
Synthesis and biological activity of 22-deoxo-23-oxa analogues of saponin OSW-1.
Journal of medicinal chemistry 2011;54(9):3298-305.
2011: Silvia Gajdosová; Lukás Spíchal; Miroslav Kamínek; Klára Hoyerová; Ondrej Novák; Petre I Dobrev; Petr Galuszka; Petr Klíma; Alena Gaudinová; Eva Zizková; Jan Hanus; Martin Dancák; Bohumil Trávnícek; Bedrich Pesek; Martin Krupicka; Radomíra Vanková; Miroslav Strnad; Václav Motyka
Distribution, biological activities, metabolism, and the conceivable function of cis-zeatin-type cytokinins in plants.
Journal of experimental botany 2011;62(8):2827-40.
2011: Radek Jorda; Jirí Bártek; Libor Havlícek; Marek Kuzma; Iain W McNae; Martin Mistrík; Jana Navrátilová; Miroslav Strnad; Antonín Sturc; Jirí Voller; Malcolm D Walkinshaw; Vladimír Krystof
Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity.
Journal of medicinal chemistry 2011;54(8):2980-93.
2011: Isabel Bartrina; Elisabeth Otto; Miroslav Strnad; Tomás Werner; Thomas Schmülling
Cytokinin regulates the activity of reproductive meristems, flower organ size, ovule formation, and thus seed yield in Arabidopsis thaliana.
The Plant cell 2011;23(1):69-80.
2010: Jana Steigerová; Jana Oklešťková; Monika Levková; Lucie Rárová; Zdeněk Kolář; Miroslav Strnad
Brassinosteroids cause cell cycle arrest and apoptosis of human breast cancer cells.
Chemico-biological interactions 2010;188(3):487-96.
2010: Tomás Werner; Erika Nehnevajova; Ireen Köllmer; Ondrej Novák; Miroslav Strnad; Ute Krämer; Thomas Schmülling
Root-specific reduction of cytokinin causes enhanced root growth, drought tolerance, and leaf mineral enrichment in Arabidopsis and tobacco.
The Plant cell 2010;22(12):3905-20.
2010: Petr Tarkowski; Kateřina Václavíková; Ondrej Novák; Ine Pertry; Jan Hanuš; Robert Whenham; Danny Vereecke; Marek Šebela; Miroslav Strnad
Analysis of 2-methylthio-derivatives of isoprenoid cytokinins by liquid chromatography-tandem mass spectrometry.
Analytica chimica acta 2010;680(1-2):86-91.
2010: Tibor Béres; Marek Zatloukal; Jiří Voller; Percy Niemann; Marie Christin Gahsche; Petr Tarkowski; Ondrej Novák; Jan Hanuš; Miroslav Strnad; Karel Doležal
Tandem mass spectrometry identification and LC-MS quantification of intact cytokinin nucleotides in K-562 human leukemia cells.
Analytical and bioanalytical chemistry 2010;398(5):2071-80.
2010: Ine Pertry; Katerina Václavíková; Markéta Gemrotová; Lukás Spíchal; Petr Galuszka; Stephen Depuydt; Wim Temmerman; Elisabeth Stes; Annick De Keyser; Michael Riefler; Stefania Biondi; Ondrej Novák; Thomas Schmülling; Miroslav Strnad; Petr Tarkowski; Marcelle Holsters; Danny Vereecke
Rhodococcus fascians impacts plant development through the dynamic fas-mediated production of a cytokinin mix.
Molecular plant-microbe interactions : MPMI 2010;23(9):1164-74.
2010: Jirí Voller; Marek Zatloukal; René Lenobel; Karel Dolezal; Tibor Béres; Vladimír Krystof; Lukás Spíchal; Percy Niemann; Petr Dzubák; Marián Hajdúch; Miroslav Strnad
Anticancer activity of natural cytokinins: a structure-activity relationship study.
Phytochemistry 2010;71(11-12):1350-9.
2010: Jaroslav Nisler; Marek Zatloukal; Igor Popa; Karel Dolezal; Miroslav Strnad; Lukás Spíchal
Cytokinin receptor antagonists derived from 6-benzylaminopurine.
Phytochemistry 2010;71(7):823-30.
2009: Ales Pencík; Jakub Rolcík; Ondrej Novák; Volker Magnus; Petr Barták; Roman Buchtík; Branka Salopek-Sondi; Miroslav Strnad
Isolation of novel indole-3-acetic acid conjugates by immunoaffinity extraction.
Talanta 2009;80(2):651-5.
2009: Ada Linkies; Kerstin Müller; Karl Morris; Veronika Turecková; Meike Wenk; Cassandra S C Cadman; Françoise Corbineau; Miroslav Strnad; James R Lynn; William E Finch-Savage; Gerhard Leubner-Metzger
Ethylene interacts with abscisic acid to regulate endosperm rupture during germination: a comparative approach using Lepidium sativum and Arabidopsis thaliana.
The Plant cell 2009;21(12):3803-22.
2009: Veronika Turecková; Ondrej Novák; Miroslav Strnad
Profiling ABA metabolites in Nicotiana tabacum L. leaves by ultra-performance liquid chromatography-electrospray tandem mass spectrometry.
Talanta 2009;80(1):390-9.
2009: Glendon D Ascough; Ondrej Novák; Ales Pencík; Jakub Rolcík; Miroslav Strnad; John E Erwin; Johannes Van Staden
Hormonal and cell division analyses in Watsonia lepida seedlings.
Journal of plant physiology 2009;166(14):1497-507.
2009: Martina Paprskárová; Vladimír Krystof; Radek Jorda; Petr Dzubák; Marián Hajdúch; Józefa Wesierska-Gadek; Miroslav Strnad
Functional p53 in cells contributes to the anticancer effect of the cyclin-dependent kinase inhibitor roscovitine.
Journal of cellular biochemistry 2009;107(3):428-37.
2009: Lucie Szücová; Lukás Spíchal; Karel Dolezal; Marek Zatloukal; Jarmila Greplová; Petr Galuszka; Vladimír Krystof; Jirí Voller; Igor Popa; Frank J Massino; Jan-Elo Jørgensen; Miroslav Strnad
Synthesis, characterization and biological activity of ring-substituted 6-benzylamino-9-tetrahydropyran-2-yl and 9-tetrahydrofuran-2-ylpurine derivatives.
Bioorganic & medicinal chemistry 2009;17(5):1938-47.
2009: Ine Pertry; Katerina Václavíková; Stephen Depuydt; Petr Galuszka; Lukás Spíchal; Wim Temmerman; Elisabeth Stes; Thomas Schmülling; Tatsuo Kakimoto; Marc C E Van Montagu; Miroslav Strnad; Marcelle Holsters; Petr Tarkowski; Danny Vereecke
Identification of Rhodococcus fascians cytokinins and their modus operandi to reshape the plant.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(3):929-34.
2008: Marek Zatloukal; Markéta Gemrotová; Karel Dolezal; Libor Havlícek; Lukás Spíchal; Miroslav Strnad
Novel potent inhibitors of A. thaliana cytokinin oxidase/dehydrogenase.
Bioorganic & medicinal chemistry 2008;16(20):9268-75.
2008: Ondrej Novák; Eva Hauserová; Petra Amakorová; Karel Dolezal; Miroslav Strnad
Cytokinin profiling in plant tissues using ultra-performance liquid chromatography-electrospray tandem mass spectrometry.
Phytochemistry 2008;69(11):2214-24.
2008: Piotr Cmoch; Zbigniew Pakulski; Jana Swaczynová; Miroslav Strnad
Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents.
Carbohydrate research 2008;343(6):995-1003.
2008: Jana Malíková; Jana Swaczynová; Zdenek Kolár; Miroslav Strnad
Anticancer and antiproliferative activity of natural brassinosteroids.
Phytochemistry 2008;69(2):418-26.
2007: Klaus von Schwartzenberg; Marta Fernández Núñez; Hanna Blaschke; Petre I Dobrev; Ondrej Novák; Václav Motyka; Miroslav Strnad
Cytokinins in the bryophyte Physcomitrella patens: analyses of activity, distribution, and cytokinin oxidase/dehydrogenase overexpression reveal the role of extracellular cytokinins.
Plant physiology 2007;145(3):786-800.
2007: H Kolarova; René Lenobel; P Kolar; Miroslav Strnad
Sensitivity of different cell lines to phototoxic effect of disulfonated chloroaluminium phthalocyanine.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(7):1304-6.
2007: Agnieszka Wojtkielewicz; Maciej Długosz; Jadwiga Maj; Jacek W Morzycki; Michał Nowakowski; Joanna Renkiewicz; Miroslav Strnad; Jana Swaczynová; Agnieszka Z Wilczewska; Jacek Wójcik
New analogues of the potent cytotoxic saponin OSW-1.
Journal of medicinal chemistry 2007;50(15):3667-73.
2007: Karel Dolezal; Igor Popa; Eva Hauserová; Lukás Spíchal; Kuheli Chakrabarty; Ondrej Novák; Vladimír Krystof; Jirí Voller; Jan Holub; Miroslav Strnad
Preparation, biological activity and endogenous occurrence of N6-benzyladenosines.
Bioorganic & medicinal chemistry 2007;15(11):3737-47.
2007: Lukás Spíchal; Vladimír Krystof; Martina Paprskárová; René Lenobel; Jakub Styskala; Pavla Binarová; Vera Cenklová; Lieven De Veylder; Dirk Inzé; George Kontopidis; Peter M Fischer; Thomas Schmülling; Miroslav Strnad
Classical anticytokinins do not interact with cytokinin receptors but inhibit cyclin-dependent kinases.
The Journal of biological chemistry 2007;282(19):14356-63.
2007: H Kolarova; P Nevrelova; Robert Bajgar; D Jirova; K Kejlova; Miroslav Strnad
In vitro photodynamic therapy on melanoma cell lines with phthalocyanine.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(2):249-53.
2007: Veronika Hradecká; Ondrej Novák; Libor Havlícek; Miroslav Strnad
Immunoaffinity chromatography of abscisic acid combined with electrospray liquid chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;847(2):162-73.
2006: Vladimír Krystof; Daniela Moravcová; Martina Paprskárová; pascale barbier; Vincent Peyrot; Alice Hlobilková; Libor Havlícek; Miroslav Strnad
Synthesis and biological activity of 8-azapurine and pyrazolo[4,3-d]pyrimidine analogues of myoseverin.
European journal of medicinal chemistry 2006;41(12):1405-11.
2006: Vladimíra Hlavácková; Pavel Krchnák; Jan Naus; Ondrej Novák; Martina Spundová; Miroslav Strnad
Electrical and chemical signals involved in short-term systemic photosynthetic responses of tobacco plants to local burning.
Planta 2006;225(1):235-44.
2006: Vladimír Krystof; Petr Cankar; Iveta Frysová; Jan Slouka; George Kontopidis; Petr Dzubák; Marián Hajdúch; Josef Srovnal; Walter F de Azevedo; Martin Orság; Martina Paprskárová; Jakub Rolcík; Ales Látr; Peter M Fischer; Miroslav Strnad
4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects.
Journal of medicinal chemistry 2006;49(22):6500-9.
2006: Paulina Dluzniewska; Arthur Gessler; Stanislav Kopriva; Miroslav Strnad; Ondrej Novák; Henriette Dietrich; Heinz Rennenberg
Exogenous supply of glutamine and active cytokinin to the roots reduces NO3- uptake rates in poplar.
Plant, cell & environment 2006;29(7):1284-97.
2006: Petr Dobes; Michal Otyepka; Miroslav Strnad; Pavel Hobza
Interaction energies for the purine inhibitor roscovitine with cyclin-dependent kinase 2: correlated ab initio quantum-chemical, DFT and empirical calculations.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(16):4297-304.
2006: Karel Dolezal; Igor Popa; Vladimír Krystof; Lukás Spíchal; Martina Fojtíková; Jan Holub; René Lenobel; Thomas Schmülling; Miroslav Strnad
Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells.
Bioorganic & medicinal chemistry 2006;14(3):875-84.
2006: Petr Tarkowski; Danuse Tarkowská; Ondrej Novák; Snjezana Mihaljevic; Volker Magnus; Miroslav Strnad; Branka Salopek-Sondi
Cytokinins in the perianth, carpels, and developing fruit of Helleborus niger L.
Journal of experimental botany 2006;57(10):2237-47.
2006: Michael Riefler; Ondrej Novak; Miroslav Strnad; Thomas Schmülling
Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism.
The Plant cell 2006;18(1):40-54.
2005: Eva Hauserová; Jana Swaczynová; Karel Dolezal; René Lenobel; Igor Popa; Marián Hajdúch; David Vydra; Kvetoslava Fuksová; Miroslav Strnad
Batch immunoextraction method for efficient purification of aromatic cytokinins.
Journal of chromatography. A 2005;1100(1):116-25.
2005: Georgy A Romanov; Lukás Spíchal; Sergey N Lomin; Miroslav Strnad; Thomas Schmülling
A live cell hormone-binding assay on transgenic bacteria expressing a eukaryotic receptor protein.
Analytical biochemistry 2005;347(1):129-34.
2005: Michal Malon; Zdenek Trávnícek; Radek Marek; Miroslav Strnad
Synthesis, spectral study and cytotoxicity of platinum(II) complexes with 2,9-disubstituted-6-benzylaminopurines.
Journal of inorganic biochemistry 2005;99(11):2127-38.
2005: H Kolarova; Jaroslav Macecek; P Nevrelova; Martin Huf; Marek Tomecka; Robert Bajgar; Jirí Mosinger; Miroslav Strnad
Photodynamic therapy with zinc-tetra(p-sulfophenyl)porphyrin bound to cyclodextrin induces single strand breaks of cellular DNA in G361 melanoma cells.
Toxicology in vitro : an international journal published in association with BIBRA 2005;19(7):971-4.
2005: Libor Havlicek; Kveta Fuksova; Vladimír Krystof; Martin Orsag; Borivoj Vojtesek; Miroslav Strnad
8-Azapurines as new inhibitors of cyclin-dependent kinases.
Bioorganic & medicinal chemistry 2005;13(18):5399-407.
2005: Jakub Rolcík; Jana Recinská; Petr Bartak; Miroslav Strnad; Els Prinsen
Purification of 3-indolylacetic acid by solid phase extraction.
Journal of separation science 2005;28(12):1370-4.
2005: Vladimír Krystof; Iain W McNae; Malcolm D Walkinshaw; Peter M Fischer; P Müller; Borivoj Vojtesek; M Orság; Libor Havlícek; Miroslav Strnad
Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor.
Cellular and molecular life sciences : CMLS 2005;62(15):1763-71.
2004: Petr Galuszka; Jitka Frébortová; Tomás Werner; Mamoru Yamada; Miroslav Strnad; Thomas Schmülling; Ivo Frébort
Cytokinin oxidase/dehydrogenase genes in barley and wheat: cloning and heterologous expression.
European journal of biochemistry / FEBS 2004;271(20):3990-4002.
2004: Lukás Spíchal; Natalia Yu Rakova; Michael Riefler; Takeshi Mizuno; Georgy A Romanov; Miroslav Strnad; Thomas Schmülling
Two cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, differ in their ligand specificity in a bacterial assay.
Plant & cell physiology 2004;45(9):1299-305.
2004: Hana Kolárová; Martin Huf; Jaroslav Macedek; Pavla Nevrelová; Marek Tomecka; Robert Bajgar; Jirí Mosinger; Miroslav Strnad
The cellular uptake of sensitizers bound to cyclodextrin carriers.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2004;47(4):313-5.
2004: Martin Huf; Hana Kolárová; Robert Bajgar; Jaroslav Macecek; Marek Tomecka; Pavla Nevrelová; Jirí Mosinger; Pavel Tomek; Miroslav Strnad
Spectral characteristics of the supramolecular complexes of polypyrrolic sensitizers and cyclodextrin carriers: usage in photodynamic therapy of tumors.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2004;47(4):309-11.
2004: Jana Knillová; Jan Bouchal; Alice Hlobilková; Miroslav Strnad; Zdenek Kolár
Synergic effects of the cyclin-dependent kinase (CDK) inhibitor olomoucine and androgen-antagonist bicalutamide on prostatic cancer cell lines.
Neoplasma 2004;51(5):358-67.
2003: Hana Kolárová; Jirí Mosinger; René Lenobel; K Kejlová; D Jírová; Miroslav Strnad
In vitro toxicity testing of supramolecular sensitizers for photodynamic therapy.
Toxicology in vitro : an international journal published in association with BIBRA 2003;17(5-6):775-8.
2003: Jirí Moravec; Vladimír Krystof; Jan Hanus; Libor Havlícek; Daniela Moravcová; Kvetoslava Fuksová; Marek Kuzma; René Lenobel; Michal Otyepka; Miroslav Strnad
2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors.
Bioorganic & medicinal chemistry letters 2003;13(18):2993-6.
2003: Daniela Moravcová; Vladimír Krystof; Libor Havlícek; Jirí Moravec; René Lenobel; Miroslav Strnad
Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.
Bioorganic & medicinal chemistry letters 2003;13(18):2989-92.
2003: Zdenek Trávnícek; Michal Malon; Marek Zatloukal; Karel Dolezal; Miroslav Strnad; Jaromír Marek
Mixed ligand complexes of platinum(II) and palladium(II) with cytokinin-derived compounds Bohemine and Olomoucine: X-ray structure of [Pt(BohH+-N7)Cl(3)].9/5H2O [Boh=6-(benzylamino)-2-[(3-(hydroxypropyl)-amino]-9-isopropylpurine, Bohemine].
Journal of inorganic biochemistry 2003;94(4):307-16.
2003: Kris Laukens; René Lenobel; Miroslav Strnad; Harry Van Onckelen; Erwin Witters
Cytokinin affinity purification and identification of a tobacco BY-2 adenosine kinase.
FEBS letters 2003;533(1-3):63-6.
2002: Vladimír Krystof; René Lenobel; Libor Havlícek; Marek Kuzma; Miroslav Strnad
Synthesis and biological activity of olomoucine II.
Bioorganic & medicinal chemistry letters 2002;12(22):3283-6.
2002: Katrien Vermeulen; Miroslav Strnad; Libor Havlícek; Harry Van Onckelen; Marc Lenjou; Griet Nijs; Dirk R Van Bockstaele; Zwi N Berneman
Plant cytokinin analogues with inhibitory activity on cyclin-dependent kinases exert their antiproliferative effect through induction of apoptosis initiated by the mitochondrial pathway: determination by a multiparametric flow cytometric analysis.
Experimental hematology 2002;30(10):1107-14.
2002: Jana Mad'arová; M Lukesová; Alice Hlobilková; Miroslav Strnad; Borivoj Vojtesek; René Lenobel; Marián Hajdúch; Paul G Murray; S Perera; Zdenek Kolár
Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines.
Molecular pathology : MP 2002;55(4):227-34.
2002: Jakub Rolcík; René Lenobel; Vĕra Siglerová; Miroslav Strnad
Isolation of melatonin by immunoaffinity chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;775(1):9-15.
2002: Katrien Vermeulen; Miroslav Strnad; Vladimír Krystof; Libor Havlícek; A Van der Aa; Marc Lenjou; Griet Nijs; Inez E Rodrigus; Bernard A Stockman; Harry Van Onckelen; Dirk R Van Bockstaele; Zwi N Berneman
Antiproliferative effect of plant cytokinin analogues with an inhibitory activity on cyclin-dependent kinases.
Leukemia 2002;16(3):299-305.
2001: Tomás Werner; Václav Motyka; Miroslav Strnad; Thomas Schmülling
Regulation of plant growth by cytokinin.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10487-92.
2001: Frantisek Franek; Miroslav Strnad; Libor Havlícek; V Siglerová; I Fismolová; Tomás Eckschlager
Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture.
Cytotechnology 2001;36(1-3):117-23.
2001: Zdenek Trávnícek; Michal Malon; Z Sindelál; Karel Dolezal; Jakub Rolcík; Vladimír Krystof; Miroslav Strnad; Jaromír Marek
Preparation, physicochemical properties and biological activity of copper(II) complexes with 6-(2-chlorobenzylamino)purine (HL1) or 6-(3-chlorobenzylamino)purine (HL2). The single-crystal X-ray structure of.
Journal of inorganic biochemistry 2001;84(1-2):23-32.
2000: Hana Kovárová; Marián Hajdúch; G Korínková; Petr Halada; S Krupicková; A Gouldsworthy; Nikolai Z Zhelev; Miroslav Strnad
Proteomics approach in classifying the biochemical basis of the anticancer activity of the new olomoucine-derived synthetic cyclin-dependent kinase inhibitor, bohemine.
Electrophoresis 2000;21(17):3757-64.
2000: Michal Otyepka; Vladimír Krystof; Libor Havlícek; V Siglerová; Miroslav Strnad; Jaroslav Koca
Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2.
Journal of medicinal chemistry 2000;43(13):2506-13.
1999: H M Rupp; Markus Frank; Tomás Werner; Miroslav Strnad; Thomas Schmülling
Increased steady state mRNA levels of the STM and KNAT1 homeobox genes in cytokinin overproducing Arabidopsis thaliana indicate a role for cytokinins in the shoot apical meristem.
The Plant journal : for cell and molecular biology 1999;18(5):557-63.
1999: Marián Hajdúch; L Havlíèek; J Veselý; R Novotný; Vladimír Mihál; Miroslav Strnad
Synthetic cyclin dependent kinase inhibitors. New generation of potent anti-cancer drugs.
Advances in experimental medicine and biology 1999;457():341-53.
1998: Pavla Binarová; Jaroslav Dolezel; P Draber; Erwin Heberle-Bors; Miroslav Strnad; László Bögre
Treatment of Vicia faba root tip cells with specific inhibitors to cyclin-dependent kinases leads to abnormal spindle formation.
The Plant journal : for cell and molecular biology 1998;16(6):697-707.
1998: Petr Galuszka; Marek Sebela; Lenka Luhová; Ludmila Zajoncová; Ivo Frébort; Miroslav Strnad; Pavel Pec
Cytokinins as inhibitors of plant amine oxidase.
Journal of enzyme inhibition 1998;13(6):457-63.
1998: R Vankova; Alena Gaudinová; H Süssenbeková; Petre I Dobrev; Miroslav Strnad; J Holík; J Lenfeld
Comparison of oriented and random antibody immobilization in immunoaffinity chromatography of cytokinins.
Journal of chromatography. A 1998;811(1-2):77-84.
1998: Hana Kolárová; L Kotala; Miroslav Strnad; M Bancírová; J Lasovský; P Ambrozová
[Fluorescence methods for studying cell damage].
Sborník lékar̆ský 1998;99(4):437-42.
1997: Marián Hajdúch; Zdenek Kolár; R Novotný; Jan Hanus; Vladimír Mihál; A Hlobílková; Vera Nosková; Miroslav Strnad
Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin-dependent kinase inhibitor olomoucine.
Anti-cancer drugs 1997;8(10):1007-13.
1997: M Faiss; J Zalubìlová; Miroslav Strnad; Thomas Schmülling
Conditional transgenic expression of the ipt gene indicates a function for cytokinins in paracrine signaling in whole tobacco plants.
The Plant journal : for cell and molecular biology 1997;12(2):401-15.
1997: Libor Havlícek; Jan Hanus; Jaroslav Veselý; S Leclerc; L Meijer; G Shaw; Miroslav Strnad
Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.
Journal of medicinal chemistry 1997;40(4):408-12.
1994: J Veselý; L Havlicek; Miroslav Strnad; Jackson Blow; A Donella-Deana; L Pinna; D S Letham; J Kato; L Detivaud; S Leclerc
Inhibition of cyclin-dependent kinases by purine analogues.
European journal of biochemistry / FEBS 1994;224(2):771-86.