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Christopher Stubbs

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Rats

Anatomy

Lipid Bilayers

Physiology

Enzyme Activation

Phenomena

Fluorescence Polarization

Procedures

Fluorescence Spectrometry

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Network (preview)

Co-Publications
Name
24
Slater, Simon
20
Ho, Cojen
10
Stagliano, Brigid
9
Taddeo, FJ
5
Milano, Shawn
5
Seiz, Jodie
3
Malinowski, Steve
3
Mazurek, Anthony
3
Kelly, MB
3
Cook, Anthony
3
Gergich, KJ
2
Hoek, Jan
1
Larkin, Jonathan
1
Botchway, Stanley
1
Buzas, Christopher

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Publications

TOP 3
Stubbs Christopher D; Botchway Stanley W; Slater Simon J; Parker Anthony W
The use of time-resolved fluorescence imaging in the study of protein kinase C localisation in cells.
Slater Simon J; Malinowski Steve A; Stubbs Christopher D
The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha.
Slater Simon J; Cook Anthony C; Seiz Jodie L; Malinowski Steve A; Stagliano Brigid A; Stubbs Christopher D
Effects of ethanol on protein kinase C alpha activity induced by association with Rho GTPases.

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All Publications

2005: Stubbs Christopher D; Botchway Stanley W; Slater Simon J; Parker Anthony W
The use of time-resolved fluorescence imaging in the study of protein kinase C localisation in cells.
BMC cell biology 2005;6(1):22.
2004: Slater Simon J; Malinowski Steve A; Stubbs Christopher D
The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha.
Biochemistry 2004;43(23):7601-9.
2003: Slater Simon J; Cook Anthony C; Seiz Jodie L; Malinowski Steve A; Stagliano Brigid A; Stubbs Christopher D
Effects of ethanol on protein kinase C alpha activity induced by association with Rho GTPases.
Biochemistry 2003;42(41):12105-14.
2002: Slater Simon J; Ho Cojen; Stubbs Christopher D
The use of fluorescent phorbol esters in studies of protein kinase C-membrane interactions.
Chemistry and physics of lipids 2002;116(1-2):75-91.
2002: Slater Simon J; Seiz Jodie L; Cook Anthony C; Buzas Christopher J; Malinowski Steve A; Kershner Jennifer L; Stagliano Brigid A; Stubbs Christopher D
Regulation of PKC alpha activity by C1-C2 domain interactions.
The Journal of biological chemistry 2002;277(18):15277-85.
2001: Ho C; Slater S J; Stagliano B; Stubbs C D
The C1 domain of protein kinase C as a lipid bilayer surface sensing module.
Biochemistry 2001;40(34):10334-41.
2001: Slater S J; Seiz J L; Stagliano B A; Cook A C; Milano S K; Ho C; Stubbs C D
Low- and high-affinity phorbol ester and diglyceride interactions with protein kinase C: 1-O-alkyl-2-acyl-sn-glycerol enhances phorbol ester- and diacylglycerol-induced activity but alone does not induce activity.
Biochemistry 2001;40(20):6085-92.
2001: Slater S J; Seiz J L; Stagliano B A; Stubbs C D
Interaction of protein kinase C isozymes with Rho GTPases.
Biochemistry 2001;40(14):4437-45.
2001: Slater S J; Stagliano B A; Seiz J L; Curry J P; Milano S K; Gergich K J; Stubbs C D
Effects of ethanol on protein kinase C activity induced by filamentous actin.
Biochimica et biophysica acta 2001;1544(1-2):207-16.
2000: Slater S J; Milano S K; Stagliano B A; Gergich K J; Curry J P; Taddeo F J; Stubbs C D
Interaction of protein kinase C with filamentous actin: isozyme specificity resulting from divergent phorbol ester and calcium dependencies.
Biochemistry 2000;39(2):271-80.
1999: Ho C; Slater S J; Stagliano B A; Stubbs C D
Conformation of the C1 phorbol-ester-binding domain participates in the activating conformational change of protein kinase C.
The Biochemical journal 1999;344 Pt 2():451-60.
1999: Stubbs C D; Slater S J
Ethanol and protein kinase C.
Alcoholism, clinical and experimental research 1999;23(9):1552-60.
1999: Slater S J; Milano S K; Stagliano B A; Gergich K J; Ho C; Mazurek A; Taddeo F J; Kelly M B; Yeager M D; Stubbs C D
Synergistic activation of protein kinase Calpha, -betaI, and -gamma isoforms induced by diacylglycerol and phorbol ester: roles of membrane association and activating conformational changes.
Biochemistry 1999;38(12):3804-15.
1998: Slater S J; Taddeo F J; Mazurek A; Stagliano B A; Milano S K; Kelly M B; Ho C; Stubbs C D
Inhibition of membrane lipid-independent protein kinase Calpha activity by phorbol esters, diacylglycerols, and bryostatin-1.
The Journal of biological chemistry 1998;273(36):23160-8.
1997: Ho C; Stubbs C D
Effect of n-alkanols on lipid bilayer hydration.
Biochemistry 1997;36(35):10630-7.
1997: Slater S J; Kelly M B; Larkin J D; Ho C; Mazurek A; Taddeo F J; Yeager M D; Stubbs C D
Interaction of alcohols and anesthetics with protein kinase Calpha.
The Journal of biological chemistry 1997;272(10):6167-73.
1996: Stubbs C D; Slater S J
The effects of non-lamellar forming lipids on membrane protein-lipid interactions.
Chemistry and physics of lipids 1996;81(2):185-95.
1996: Slater S J; Kelly M B; Yeager M D; Larkin J; Ho C; Stubbs C D
Polyunsaturation in cell membranes and lipid bilayers and its effects on membrane proteins.
Lipids 1996;31 Suppl():S189-92.
1996: Slater S J; Ho C; Kelly M B; Larkin J D; Taddeo F J; Yeager M D; Stubbs C D
Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities.
The Journal of biological chemistry 1996;271(9):4627-31.
1995: Ho C; Slater S J; Stubbs C D
Hydration and order in lipid bilayers.
Biochemistry 1995;34(18):6188-95.
1995: Slater S J; Kelly M B; Taddeo F J; Larkin J D; Yeager M D; McLane J A; Ho C; Stubbs C D
Direct activation of protein kinase C by 1 alpha,25-dihydroxyvitamin D3.
The Journal of biological chemistry 1995;270(12):6639-43.
1994: Ho C; Kelly M B; Stubbs C D
The effects of phospholipid unsaturation and alcohol perturbation at the protein/lipid interface probed using fluorophore lifetime heterogeneity.
Biochimica et biophysica acta 1994;1193(2):307-15.
1994: Slater S J; Kelly M B; Taddeo F J; Rubin E; Stubbs C D
Evidence for discrete diacylglycerol and phorbol ester activator sites on protein kinase C. Differences in effects of 1-alkanol inhibition, activation by phosphatidylethanolamine and calcium chelation.
The Journal of biological chemistry 1994;269(25):17160-5.
1994: Slater S J; Kelly M B; Taddeo F J; Ho C; Rubin E; Stubbs C D
The modulation of protein kinase C activity by membrane lipid bilayer structure.
The Journal of biological chemistry 1994;269(7):4866-71.
1994: Ho C; Williams B W; Kelly M B; Stubbs C D
Chronic ethanol intoxication induces adaptive changes at the membrane protein/lipid interface.
Biochimica et biophysica acta 1994;1189(2):135-42.
1993: Rooney T A; Hager R; Stubbs C D; Thomas A P
Halothane regulates G-protein-dependent phospholipase C activity in turkey erythrocyte membranes.
The Journal of biological chemistry 1993;268(21):15550-6.
1993: Slater S J; Cox K J; Lombardi J V; Ho C; Kelly M B; Rubin E; Stubbs C D
Inhibition of protein kinase C by alcohols and anaesthetics.
Nature 1993;364(6432):82-4.
1993: Slater S J; Ho C; Taddeo F J; Kelly M B; Stubbs C D
Contribution of hydrogen bonding to lipid-lipid interactions in membranes and the role of lipid order: effects of cholesterol, increased phospholipid unsaturation, and ethanol.
Biochemistry 1993;32(14):3714-21.
1992: Ho C; Stubbs C D
Hydration at the membrane protein-lipid interface.
Biophysical journal 1992;63(4):897-902.
1992: Stubbs C D; Rubin R
Effect of ethanol on platelet phospholipase A2.
Lipids 1992;27(4):255-60.
1992: Ho C; Williams B W; Stubbs C D
Analysis of cell membrane micro-heterogeneity using the fluorescence lifetime of DPH-type fluorophores.
Biochimica et biophysica acta 1992;1104(2):273-82.
1992: Cox K J; Ho C; Lombardi J V; Stubbs C D
Gramicidin conformational studies with mixed-chain unsaturated phospholipid bilayer systems.
Biochemistry 1992;31(4):1112-7.
1991: Stubbs C D; Kisielewski A E; Rubin E
Chronic ethanol ingestion modifies liver microsomal phosphatidylserine inducing resistance to hydrolysis by exogenous phospholipase A2.
Biochimica et biophysica acta 1991;1070(2):349-54.
1990: Stubbs C D; Smith A D
Essential fatty acids in membrane: physical properties and function.
Biochemical Society transactions 1990;18(5):779-81.
1990: Stubbs C D; Kisielewski A E
Effect of increasing the level of omega-3 fatty acids on rat skeletal muscle sarcoplasmic reticulum.
Lipids 1990;25(9):553-8.
1990: Williams B W; Scotto A W; Stubbs C D
Effect of proteins on fluorophore lifetime heterogeneity in lipid bilayers.
Biochemistry 1990;29(13):3248-55.
1989: Stubbs C D; Williams B W; Boni L T; Hoek J B; Taraschi T F; Rubin E
On the use of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)phosphatidylethanolamine in the study of lipid polymorphism.
Biochimica et biophysica acta 1989;986(1):89-96.
1989: Nie Y; Stubbs C D; Williams B W; Rubin E
Ethanol causes decreased partitioning into biological membranes without changes in lipid order.
Archives of biochemistry and biophysics 1989;268(1):349-59.
1988: Williams B W; Stubbs C D
Properties influencing fluorophore lifetime distributions in lipid bilayers.
Biochemistry 1988;27(21):7994-9.
1988: Stubbs C D; Williams B W; Pryor C L; Rubin E
Ethanol-induced modifications to membrane lipid structure: effect on phospholipase A2-membrane interactions.
Archives of biochemistry and biophysics 1988;262(2):560-73.
1988: Hoek J B; Harada N; Moehren G; Tomsho M; Stubbs C D
The role of calcium and phospholipase A2 in glucagon-induced enhancement of mitochondrial calcium retention.
Advances in experimental medicine and biology 1988;232():25-36.
1986: Conroy D M; Stubbs C D; Belin J; Pryor C L; Smith A D
The effects of dietary (n-3) fatty acid supplementation on lipid dynamics and composition in rat lymphocytes and liver microsomes.
Biochimica et biophysica acta 1986;861(3):457-62.
1980: Stubbs C D; Tsang W M; Belin J; Smith A D; Johnson S M
Incubation of exogenous fatty acids with lymphocytes. Changes in fatty acid composition and effects on the rotational relaxation time of 1,6-diphenyl-1,3,5-hexatriene.
Biochemistry 1980;19(12):2756-62.

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