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Marion Stubbs

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Loreta M Rodrigues; Swee Y Sharp; Marion Stubbs; Nada M S Al Saffar; Udai Banerji; Yuen-Li Chung; John R Griffiths; Laura E Jackson; Martin O Leach; Paul Workman
Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.
Dominick J O McIntyre; Marion Stubbs; Franklyn Arron Howe; Christophe Ladroue; Fiona Lofts; John R Griffiths
Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response?
Monika Golinska; Eric O Aboagye; Rachel E Airley; Yuen-Li Chung; Adrian L Harris; John Latigo; Lucy Ly; Manuel Mayr; Paul M McSheehy; David Perrett; Meg Perumal; Marion Stubbs; Helen Troy; Kaye J Williams; Xiaoke Yin; John R Griffiths
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.

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2012: Loreta M Rodrigues; Swee Y Sharp; Marion Stubbs; Nada M S Al Saffar; Udai Banerji; Yuen-Li Chung; John R Griffiths; Laura E Jackson; Martin O Leach; Paul Workman
Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy.
BMC research notes 2012;5():250.
2011: Dominick J O McIntyre; Marion Stubbs; Franklyn Arron Howe; Christophe Ladroue; Fiona Lofts; John R Griffiths
Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response?
Cancer chemotherapy and pharmacology 2011;68(1):29-36.
2011: Monika Golinska; Eric O Aboagye; Rachel E Airley; Yuen-Li Chung; Adrian L Harris; John Latigo; Lucy Ly; Manuel Mayr; Paul M McSheehy; David Perrett; Meg Perumal; Marion Stubbs; Helen Troy; Kaye J Williams; Xiaoke Yin; John R Griffiths
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
BMC cancer 2011;11():198.
2008: Andrew Evans; Victoria Bates; Helen Troy; Stephen Hewitt; Susan Holbeck; Yuen-Li Chung; Roger Phillips; Marion Stubbs; John Griffiths; Rachel E Airley
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.
Cancer chemotherapy and pharmacology 2008;61(3):377-93.
2008: Manuel Mayr; Shamil Yusuf; Graeme Weir; Yuen-Li Chung; Ursula Mayr; Xiaoke Yin; Christophe Ladroue; Basetti Madhu; Neil Roberts; Ayesha De Souza; Salim Fredericks; Marion Stubbs; John R Griffiths; Marjan Jahangiri; Qingbo Xu; A John Camm
Combined metabolomic and proteomic analysis of human atrial fibrillation.
Journal of the American College of Cardiology 2008;51(5):585-94.
2006: Fernando Arias-Mendoza; Geoffrey S Payne; Kristen L Zakian; A J Schwarz; Marion Stubbs; Radka Stoyanova; Douglas Ballon; Franklyn Arron Howe; Jason A Koutcher; Martin Leach; John R Griffiths; Arend Heerschap; Jerry D Glickson; Sarah J Nelson; Jeffrey L Evelhoch; H Cecil Charles; Truman R Brown
In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial.
NMR in biomedicine 2006;19(4):504-12.
2005: Paul M J McSheehy; R E Port; Loreta M Rodrigues; Simon P Robinson; Marion Stubbs; K van der Borns; G J Peters; Ian R Judson; Martin Leach; John R Griffiths
Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours.
Cancer chemotherapy and pharmacology 2005;55(2):117-28.
2004: Loreta M Rodrigues; Marion Stubbs; Simon P Robinson; B Newell; J Mansi; John R Griffiths
The C-neu mammary carcinoma in Oncomice; characterization and monitoring response to treatment with herceptin by magnetic resonance methods.
Magma (New York, N.Y.) 2004;17(3-6):260-70.
2004: Yuen-Li Chung; Helen Troy; Ian R Judson; Russell Leek; Martin Leach; Marion Stubbs; Adrian L Harris; John R Griffiths
Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3863-70.
2003: Yuen-Li Chung; Helen Troy; Udai Banerji; Laura E Jackson; Mike I Walton; Marion Stubbs; John R Griffiths; Ian R Judson; Martin Leach; Paul Workman; Sabrina M Ronen
Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
Journal of the National Cancer Institute 2003;95(21):1624-33.
2003: Simon P Robinson; Paul F J W Rijken; Franklyn Arron Howe; Paul M J McSheehy; Boudewijn van der Sanden; Arend Heerschap; Marion Stubbs; Albert J van der Kogel; John R Griffiths
Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry.
Journal of magnetic resonance imaging : JMRI 2003;17(4):445-54.
2003: Marion Stubbs; CL Bashford; John R Griffiths
Understanding the tumor metabolic phenotype in the genomic era.
Current molecular medicine 2003;3(1):49-59.
2003: Franklyn Arron Howe; SJ Barton; Simon A Cudlip; Marion Stubbs; DE Saunders; M Murphy; Peter R Wilkins; Kirstie S Opstad; VL Doyle; M A McLean; B Anthony Bell; John R Griffiths
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;49(2):223-32.
2003: Franklyn Arron Howe; Simon P Robinson; Loreta M Rodrigues; Marion Stubbs; John R Griffiths
Issues in GRE & SE magnetic resonance imaging to probe tumor oxygenation.
Advances in experimental medicine and biology 2003;530():441-8.
2003: John R Griffiths; Marion Stubbs
Opportunities for studying cancer by metabolomics: preliminary observations on tumors deficient in hypoxia-inducible factor 1.
Advances in enzyme regulation 2003;43():67-76.
2002: Loreta M Rodrigues; Simon P Robinson; Paul M J McSheehy; Marion Stubbs; John R Griffiths
Enhanced uptake of ifosfamide into GH3 prolactinomas with hypercapnic hyperoxic gases monitored in vivo by (31)P MRS.
Neoplasia (New York, N.Y.) 2002;4(6):539-43.
2002: John R Griffiths; anne Rosemary Tate; Franklyn Arron Howe; Marion Stubbs
Magnetic Resonance Spectroscopy of cancer-practicalities of multi-centre trials and early results in non-Hodgkin's lymphoma.
European journal of cancer (Oxford, England : 1990) 2002;38(16):2085-93.
2002: John R Griffiths; Paul M J McSheehy; Simon P Robinson; Helen Troy; Yuen-Li Chung; Russell D Leek; Kaye J Williams; Ian J Stratford; Adrian L Harris; Marion Stubbs
Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.
Cancer research 2002;62(3):688-95.
2002: Marion Stubbs; Simon P Robinson; Chuk Hui; Natasha M Price; Loreta M Rodrigues; Franklyn Arron Howe; John R Griffiths
The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents that improve tumor oxygenation.
Advances in enzyme regulation 2002;42():131-41.
2001: Franklyn Arron Howe; Simon P Robinson; Dominick J O McIntyre; Marion Stubbs; John R Griffiths
Issues in flow and oxygenation dependent contrast (FLOOD) imaging of tumours.
NMR in biomedicine 2001;14(7-8):497-506.
2001: Simon P Robinson; Loreta M Rodrigues; Franklyn Arron Howe; Marion Stubbs; John R Griffiths
Effects of different levels of hypercapnic hyperoxia on tumour R(2)* and arterial blood gases.
Magnetic resonance imaging 2001;19(2):161-6.
2001: John R Griffiths; Dominick J O McIntyre; Franklyn Arron Howe; Marion Stubbs
Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid.
Novartis Foundation symposium 2001;240():46-62; discussion 62-7, 152-3.
2001: John R Griffiths; Dominick J O McIntyre; Franklyn Arron Howe; Paul M J McSheehy; Loreta M Rodrigues; P Wadsworth; N M Price; F Lofts; G Nicholson; Kees Smid; Paul Noordhuis; G J Peters; Marion Stubbs
Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment.
Acta oncologica (Stockholm, Sweden) 2001;40(5):609-14.
2000: Simon P Robinson; Franklyn Arron Howe; Marion Stubbs; John R Griffiths
Effects of nicotinamide and carbogen on tumour oxygenation, blood flow, energetics and blood glucose levels.
British journal of cancer 2000;82(12):2007-14.
2000: Paul M J McSheehy; Marion Stubbs; John R Griffiths
Role of pH in tumor-trapping of the anticancer drug 5-fluorouracil.
Advances in enzyme regulation 2000;40():63-80.
2000: Marion Stubbs; Paul M J McSheehy; John R Griffiths; CL Bashford
Causes and consequences of tumour acidity and implications for treatment.
Molecular medicine today 2000;6(1):15-9.
1999: Simon P Robinson; Loreta M Rodrigues; John R Griffiths; Marion Stubbs
Response of hepatoma 9618a and normal liver to host carbogen and carbon monoxide breathing.
Neoplasia (New York, N.Y.) 1999;1(6):537-43.
1999: AS Ojugo; Paul M J McSheehy; Dominick J O McIntyre; C McCoy; Marion Stubbs; Martin Leach; Ian R Judson; John R Griffiths
Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous (19)F and (31)P probes.
NMR in biomedicine 1999;12(8):495-504.
1999: Marion Stubbs; John R Griffiths
Monitoring cancer by magnetic resonance.
British journal of cancer 1999;80 Suppl 1():86-94.
1999: Marion Stubbs
Application of magnetic resonance techniques for imaging tumour physiology.
Acta oncologica (Stockholm, Sweden) 1999;38(7):845-53.
1999: Marion Stubbs; Paul M J McSheehy; John R Griffiths
Causes and consequences of acidic pH in tumors: a magnetic resonance study.
Advances in enzyme regulation 1999;39():13-30.
1998: Marion Stubbs; Simon P Robinson; Loreta M Rodrigues; Charles S Parkins; DR Collingridge; John R Griffiths
The effects of host carbogen (95% oxygen/5% carbon dioxide) breathing on metabolic characteristics of Morris hepatoma 9618a.
British journal of cancer 1998;78(11):1449-56.
1998: Zaver M Bhujwalla; C L McCoy; Jerry D Glickson; Robert J Gillies; Marion Stubbs
Estimations of intra- and extracellular volume and pH by 31P magnetic resonance spectroscopy: effect of therapy on RIF-1 tumours.
British journal of cancer 1998;78(5):606-11.
1998: Simon P Robinson; Franklyn Arron Howe; Loreta M Rodrigues; Marion Stubbs; John R Griffiths
Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow.
Seminars in radiation oncology 1998;8(3):197-207.
1998: AS Ojugo; Paul M J McSheehy; Marion Stubbs; Glenn M Alder; CL Bashford; Ross J Maxwell; Martin Leach; Ian R Judson; John R Griffiths
Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.
British journal of cancer 1998;77(6):873-9.
1997: Charles S Parkins; Michael R L Stratford; MF Dennis; Marion Stubbs; David J Chaplin
The relationship between extracellular lactate and tumour pH in a murine tumour model of ischaemia-reperfusion.
British journal of cancer 1997;75(3):319-23.
1997: Loreta M Rodrigues; Ross J Maxwell; Paul M J McSheehy; C R Pinkerton; Simon P Robinson; Marion Stubbs; John R Griffiths
In vivo detection of ifosfamide by 31P-MRS in rat tumours: increased uptake and cytotoxicity induced by carbogen breathing in GH3 prolactinomas.
British journal of cancer 1997;75(1):62-8.
1996: Marion Stubbs; A Van den Boogaart; C Lindsay Bashford; P M Miranda; Loreta M Rodrigues; Franklyn Arron Howe; John R Griffiths
31P-magnetic resonance spectroscopy studies of nucleated and non-nucleated erythrocytes; time domain data analysis (VARPRO) incorporating prior knowledge can give information on the binding of ADP.
Biochimica et biophysica acta 1996;1291(2):143-8.
1995: C L McCoy; Charles S Parkins; David J Chaplin; John R Griffiths; Loreta M Rodrigues; Marion Stubbs
The effect of blood flow modification on intra- and extracellular pH measured by 31P magnetic resonance spectroscopy in murine tumours.
British journal of cancer 1995;72(4):905-11.
1995: Michael R L Stratford; Charles S Parkins; Steven A Everett; MF Dennis; Marion Stubbs; Sally A Hill
Analysis of the acidic microenvironment in murine tumours by high-performance ion chromatography.
Journal of chromatography. A 1995;706(1-2):459-62.
1995: A van den Boogaart; Franklyn Arron Howe; Loreta M Rodrigues; Marion Stubbs; John R Griffiths
In vivo 31P MRS: absolute concentrations, signal-to-noise and prior knowledge.
NMR in biomedicine 1995;8(2):87-93.
1995: Marion Stubbs; R L Veech; John R Griffiths
Tumor metabolism: the lessons of magnetic resonance spectroscopy.
Advances in enzyme regulation 1995;35():101-15.
1994: Marion Stubbs; L Rodrigues; Franklyn Arron Howe; J Wang; K S Jeong; R L Veech; John R Griffiths
Metabolic consequences of a reversed pH gradient in rat tumors.
Cancer research 1994;54(15):4011-6.
1993: S L Howells; Ross J Maxwell; Franklyn Arron Howe; A C Peet; Marion Stubbs; Loreta M Rodrigues; Simon P Robinson; S Baluch; John R Griffiths
Pattern recognition of 31P magnetic resonance spectroscopy tumour spectra obtained in vivo.
NMR in biomedicine 1993;6(4):237-41.
1993: Franklyn Arron Howe; Marion Stubbs; Loreta M Rodrigues; John R Griffiths
An assessment of artefacts in localized and non-localized 31P MRS studies of phosphate metabolites and pH in rat tumours.
NMR in biomedicine 1993;6(1):43-52.
1992: Marion Stubbs; Zaver M Bhujwalla; G M Tozer; Loreta M Rodrigues; Ross J Maxwell; R Morgan; Franklyn Arron Howe; John R Griffiths
An assessment of 31P MRS as a method of measuring pH in rat tumours.
NMR in biomedicine 1992;5(6):351-9.
1991: S Baluch; C J Midwood; John R Griffiths; Marion Stubbs; R C Coombes
Monitoring therapeutic response to tamoxifen in NMU-induced rat mammary tumours by 31P MRS.
British journal of cancer 1991;63(6):901-4.
1990: Marion Stubbs; R C Coombes; John R Griffiths; Ross J Maxwell; Loreta M Rodrigues; barry gusterson
31P-NMR spectroscopy and histological studies of the response of rat mammary tumours to endocrine therapy.
British journal of cancer 1990;61(2):258-62.
1990: Marion Stubbs; Loreta M Rodrigues; barry gusterson; John R Griffiths
Monitoring tumor growth and regression by 31P magnetic resonance spectroscopy.
Advances in enzyme regulation 1990;30():217-30.
1989: Marion Stubbs; Loreta M Rodrigues; John R Griffiths
Growth studies of subcutaneous rat tumours: comparison of 31P-NMR spectroscopy, acid extracts and histology.
British journal of cancer 1989;60(5):701-7.
1989: Marion Stubbs; Loreta M Rodrigues; John R Griffiths
Potential artefacts from overlying tissues in 31P NMR spectra of subcutaneously implanted rat tumours.
NMR in biomedicine 1989;1(4):165-70.
1988: Marion Stubbs; F Vanstapel; Loreta M Rodrigues; John R Griffiths
Phosphate metabolites in rat skin.
NMR in biomedicine 1988;1(1):50-5.
1988: Loreta M Rodrigues; C J Midwood; R C Coombes; A N Stevens; Marion Stubbs; John R Griffiths
31P-nuclear magnetic resonance spectroscopy studies of the response of rat mammary tumors to endocrine therapy.
Cancer research 1988;48(1):89-93.