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George Studzinski

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Chemicals & Drugs

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Xiangwen Chen-Deutsch; Jonathan S Harrison; Andrzej Kutner; George P Studzinski
The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells.
Elzbieta Gocek; George P Studzinski
Genes encoding transcription factors have self-control: how important is this for cell differentiation?
H Dorota Halicka; Jiangwei Li; George P Studzinski; Frank Traganos; Hong Zhao; Zbigniew Darzynkiewicz
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3.

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2012: Xiangwen Chen-Deutsch; Jonathan S Harrison; Andrzej Kutner; George P Studzinski
The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells.
Leukemia research 2012;36(7):884-8.
2012: Elzbieta Gocek; George P Studzinski
Genes encoding transcription factors have self-control: how important is this for cell differentiation?
Leukemia research 2012;36(6):672-4.
2012: H Dorota Halicka; Jiangwei Li; George P Studzinski; Frank Traganos; Hong Zhao; Zbigniew Darzynkiewicz
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3.
Aging 2012;4(4):270-8.
2012: Xiangwen Chen-Deutsch; George P Studzinski
Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance.
Cell cycle (Georgetown, Tex.) 2012;11(7):1364-73.
2012: George P Studzinski; Geoffrey Brown; Michael Danilenko; Philip Hughes; Ewa Marcinkowska
Differentiation and cell survival of myeloid leukemia cells.
Leukemia research and treatment 2012;2012():370375.
2011: Elzbieta Gocek; Chang-Gong Liu; Xiuping Liu; Xuening Wang; George P Studzinski
MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.
Cancer research 2011;71(19):6230-9.
2011: Xuening Wang; George P Studzinski
Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells.
Journal of cellular physiology 2011;226(5):1232-40.
2011: Irene Bobilev; Victoria Novik; Itai Levi; Ofer Shpilberg; Joseph Levy; Yoav Sharoni; George P Studzinski; Michael Danilenko
The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells.
Cancer biology & therapy 2011;11(3):317-29.
2011: Jing Zhang; Jonathan S Harrison; George P Studzinski
Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D₃.
Experimental cell research 2011;317(1):117-30.
2010: Xuening Wang; Elzbieta Gocek; Victoria Novik; Jonathan S Harrison; Michael Danilenko; George P Studzinski
Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and up-regulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D(3).
Cell cycle (Georgetown, Tex.) 2010;9(22):4542-51.
2010: Jing Zhang; Jonathan S Harrison; Milan Uskokovic; Michael Danilenko; George P Studzinski
Silibinin can induce differentiation as well as enhance vitamin D3-induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors.
Hematological oncology 2010;28(3):124-32.
2010: Xuening Wang; George P Studzinski
Expression of MAP3 kinase COT1 is up-regulated by 1,25-dihydroxyvitamin D3 in parallel with activated c-jun during differentiation of human myeloid leukemia cells.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):395-8.
2010: Philip J Hughes; Ewa Marcinkowska; Elzbieta Gocek; George P Studzinski; Geoffrey Brown
Vitamin D3-driven signals for myeloid cell differentiation--implications for differentiation therapy.
Leukemia research 2010;34(5):553-65.
2010: George P Studzinski; Xuening Wang; Michael Danilenko
DNA damage response: a barrier or a path to tumor progression?
Cancer biology & therapy 2010;9(3):253-5.
2010: Stella Pesakhov; Marina Khanin; George P Studzinski; Michael Danilenko
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.
Nutrition and cancer 2010;62(6):811-24.
2009: Xiangwen Chen-Deutsch; Edward Garay; Jing Zhang; Jonathan S Harrison; George P Studzinski
c-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D.
Leukemia research 2009;33(10):1372-8.
2009: Xuening Wang; Elzbieta Gocek; Chang-gong liu; George P Studzinski
MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3.
Cell cycle (Georgetown, Tex.) 2009;8(5):736-41.
2009: Elzbieta Gocek; George P Studzinski
Vitamin D and differentiation in cancer.
Critical reviews in clinical laboratory sciences 2009;46(4):190-209.
2008: Xuening Wang; Rahul Patel; George P Studzinski
hKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cells.
Molecular cancer therapeutics 2008;7(9):2798-806.
2008: Farnaz Jamshidi; Jing Zhang; Jonathan S Harrison; Xuening Wang; George P Studzinski
Induction of differentiation of human leukemia cells by combinations of COX inhibitors and 1,25-dihydroxyvitamin D3 involves Raf1 but not Erk 1/2 signaling.
Cell cycle (Georgetown, Tex.) 2008;7(7):917-24.
2008: Ayelet Shabtay; Hagar Sharabani; Zeev Barvish; Michael Kafka; Doron Amichay; Joseph Levy; Yoav Sharoni; Milan R Uskokovic; George P Studzinski; Michael Danilenko
Synergistic antileukemic activity of carnosic acid-rich rosemary extract and the 19-nor Gemini vitamin D analogue in a mouse model of systemic acute myeloid leukemia.
Oncology 2008;75(3-4):203-14.
2007: Edward Garay; Robert Donnelly; Xuening Wang; George P Studzinski
Resistance to 1,25D-induced differentiation in human acute myeloid leukemia HL60-40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor.
Journal of cellular physiology 2007;213(3):816-25.
2007: Xuening Wang; Tian-Tian Wang; John H White; George P Studzinski
Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation.
Experimental cell research 2007;313(14):3034-45.
2007: Edward Garay; Pawel Jankowski; Paulo Lizano; Stanislaw Marczak; Hubert Maehr; Luciano Adorini; Milan R Uskokovic; George P Studzinski
Calcitriol derivatives with two different side-chains at C-20. Part 4: further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cells.
Bioorganic & medicinal chemistry 2007;15(13):4444-55.
2007: Jing Zhang; Gary H Posner; Michael Danilenko; George P Studzinski
Differentiation-inducing potency of the seco-steroid JK-1624F2-2 can be increased by combination with an antioxidant and a p38MAPK inhibitor which upregulates the JNK pathway.
The Journal of steroid biochemistry and molecular biology 2007;105(1-5):140-9.
2006: Xuening Wang; T-T Wang; J H White; George P Studzinski
Induction of kinase suppressor of RAS-1(KSR-1) gene by 1, alpha25-dihydroxyvitamin D3 in human leukemia HL60 cells through a vitamin D response element in the 5'-flanking region.
Oncogene 2006;25(53):7078-85.
2006: Xuening Wang; George P Studzinski
Raf-1 signaling is required for the later stages of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK module.
Journal of cellular physiology 2006;209(2):253-60.
2006: Ewa Marcinkowska; Edward Garay; Elzbieta Gocek; Agnieszka Chrobak; Xuening Wang; George P Studzinski
Regulation of C/EBPbeta isoforms by MAPK pathways in HL60 cells induced to differentiate by 1,25-dihydroxyvitamin D3.
Experimental cell research 2006;312(11):2054-65.
2006: Hagar Sharabani; Eugene Izumchenko; Qing Wang; Rita Kreinin; Michael Steiner; Zeev Barvish; Michael Kafka; Yoav Sharoni; Joseph Levy; Milan Uskokovic; George P Studzinski; Michael Danilenko
Cooperative antitumor effects of vitamin D3 derivatives and rosemary preparations in a mouse model of myeloid leukemia.
International journal of cancer. Journal international du cancer 2006;118(12):3012-21.
2006: Xuening Wang; George P Studzinski
The requirement for and changing composition of the activating protein-1 transcription factor during differentiation of human leukemia HL60 cells induced by 1,25-dihydroxyvitamin D3.
Cancer research 2006;66(8):4402-9.
2006: Yingyu Zhang; Jing Zhang; George P Studzinski
AKT pathway is activated by 1, 25-dihydroxyvitamin D3 and participates in its anti-apoptotic effect and cell cycle control in differentiating HL60 cells.
Cell cycle (Georgetown, Tex.) 2006;5(4):447-51.
2006: George P Studzinski; Edward Garay; R Patel; J Zhang; Xuening Wang
Vitamin D receptor signaling of monocytic differentiation in human leukemia cells: role of MAPK pathways in transcription factor activation.
Current topics in medicinal chemistry 2006;6(12):1267-71.
2005: Qing Wang; Jonathan S Harrison; M Uskokovic; Andrzej Kutner; George P Studzinski
Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant.
Leukemia 2005;19(10):1812-7.
2005: George P Studzinski; Xuening Wang; Yan Ji; Qing Wang; Yingyu Zhang; Andrzej Kutner; Jonathan S Harrison
The rationale for deltanoids in therapy for myeloid leukemia: role of KSR-MAPK-C/EBP pathway.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):47-55.
2005: Qing Wang; Hagar Salman; Michael Danilenko; George P Studzinski
Cooperation between antioxidants and 1,25-dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP-1/Egr-1 pathway.
Journal of cellular physiology 2005;204(3):964-74.
2004: Michael Danilenko; George P Studzinski
Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs.
Experimental cell research 2004;298(2):339-58.
2004: Fei Chen; Qing Wang; Xuening Wang; George P Studzinski
Up-regulation of Egr1 by 1,25-dihydroxyvitamin D3 contributes to increased expression of p35 activator of cyclin-dependent kinase 5 and consequent onset of the terminal phase of HL60 cell differentiation.
Cancer research 2004;64(15):5425-33.
2004: Zoya N Demidenko; George P Studzinski; Mikhail V Blagosklonny
From cytometry to cell cycle: a portrait of Zbigniew Darzynkiewicz.
Cell cycle (Georgetown, Tex.) 2004;3(5):525-8.
2004: F A A Weyts; Puneet Dhawan; Xiaoyu Zhang; June E Bishop; Milan R Uskokovic; Yan Ji; George P Studzinski; Anthony W Norman; Sylvia Christakos
Novel Gemini analogs of 1alpha,25-dihydroxyvitamin D(3) with enhanced transcriptional activity.
Biochemical pharmacology 2004;67(7):1327-36.
2004: Xuening Wang; George P Studzinski
Kinase suppressor of RAS (KSR) amplifies the differentiation signal provided by low concentrations 1,25-dihydroxyvitamin D3.
Journal of cellular physiology 2004;198(3):333-42.
2004: Yan Ji; George P Studzinski
Retinoblastoma protein and CCAAT/enhancer-binding protein beta are required for 1,25-dihydroxyvitamin D3-induced monocytic differentiation of HL60 cells.
Cancer research 2004;64(1):370-7.
2003: Qing Wang; Xuening Wang; George P Studzinski
Jun N-terminal kinase pathway enhances signaling of monocytic differentiation of human leukemia cells induced by 1,25-dihydroxyvitamin D3.
Journal of cellular biochemistry 2003;89(6):1087-101.
2003: Michael Danilenko; Qing Wang; Xuening Wang; Joseph Levy; Yoav Sharoni; George P Studzinski
Carnosic acid potentiates the antioxidant and prodifferentiation effects of 1alpha,25-dihydroxyvitamin D3 in leukemia cells but does not promote elevation of basal levels of intracellular calcium.
Cancer research 2003;63(6):1325-32.
2003: George P Studzinski; Jonathan S Harrison
The neuronal cyclin-dependent kinase 5 activator p35Nck5a and Cdk5 activity in monocytic cells.
Leukemia & lymphoma 2003;44(2):235-40.
2002: Yan Ji; Andrzej Kutner; Annemieke Verstuyf; Lieve Verlinden; George P Studzinski
Derivatives of vitamins D2 and D3 activate three MAPK pathways and upregulate pRb expression in differentiating HL60 cells.
Cell cycle (Georgetown, Tex.) 2002;1(6):410-5.
2002: Yan Ji; Xuening Wang; Robert J Donnelly; Milan R Uskokovic; George P Studzinski
Signaling of monocytic differentiation by a non-hypercalcemic analog of vitamin D3, 1,25(OH)2-5,6 trans-16-ene-vitamin D3, involves nuclear vitamin D receptor (nVDR) and non-nVDR-mediated pathways.
Journal of cellular physiology 2002;191(2):198-207.
2001: Michael Danilenko; Xuening Wang; George P Studzinski
Carnosic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents.
Journal of the National Cancer Institute 2001;93(16):1224-33.
2001: Xuening Wang; George P Studzinski
Phosphorylation of raf-1 by kinase suppressor of ras is inhibited by "MEK-specific" inhibitors PD 098059 and U0126 in differentiating HL60 cells.
Experimental cell research 2001;268(2):294-300.
2001: Xuening Wang; George P Studzinski
Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells.
Journal of cellular biochemistry 2001;82(1):68-77.
2001: Xuening Wang; George P Studzinski
Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells.
Journal of cellular biochemistry 2001;80(4):471-82.
2000: Xuening Wang; J Rao; George P Studzinski
Inhibition of p38 MAP kinase activity up-regulates multiple MAP kinase pathways and potentiates 1,25-dihydroxyvitamin D(3)-induced differentiation of human leukemia HL60 cells.
Experimental cell research 2000;258(2):425-37.
2000: QM Wang; Rena Feinman; Fatah Kashanchi; JM Houghton; George P Studzinski; Lawrence E Harrison
Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2951-8.
2000: QM Wang; George P Studzinski; F Chen; Frederick Coffman; Lawrence E Harrison
p53/56(lyn) antisense shifts the 1,25-dihydroxyvitamin D3-induced G1/S block in HL60 cells to S phase.
Journal of cellular physiology 2000;183(2):238-46.
2000: F Chen; J Rao; George P Studzinski
Specific association of increased cyclin-dependent kinase 5 expression with monocytic lineage of differentiation of human leukemia HL60 cells.
Journal of leukocyte biology 2000;67(4):559-66.
2000: Fei Chen; F Zhang; J Rao; George P Studzinski
Ectopic expression of truncated Sp1 transcription factor prolongs the S phase and reduces the growth rate.
Anticancer research 2000;20(2A):661-7.
1999: Lawrence E Harrison; Q M Wang; George P Studzinski
Butyrate-induced G2/M block in Caco-2 colon cancer cells is associated with decreased p34cdc2 activity.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1999;222(2):150-6.
1999: Lawrence E Harrison; Q M Wang; George P Studzinski
1,25-dihydroxyvitamin D(3)-induced retardation of the G(2)/M traverse is associated with decreased levels of p34(cdc2) in HL60 cells.
Journal of cellular biochemistry 1999;75(2):226-34.
1999: F Chen; George P Studzinski
Cyclin-dependent kinase 5 activity enhances monocytic phenotype and cell cycle traverse in 1,25-dihydroxyvitamin D3-treated HL60 cells.
Experimental cell research 1999;249(2):422-8.
1999: Frederick Coffman; George P Studzinski
Differentiation-related mechanisms which suppress DNA replication.
Experimental cell research 1999;248(1):58-73.
1999: George P Studzinski; Lawrence E Harrison
Differentiation-related changes in the cell cycle traverse.
International review of cytology 1999;189():1-58.
1998: QM Wang; Fei Chen; X Luo; D C Moore; M Flanagan; George P Studzinski
Lowering of p27Kip1 levels by its antisense or by development of resistance to 1,25-dihydroxyvitamin D3 reverses the G1 block but not differentiation of HL60 cells.
Leukemia 1998;12(8):1256-65.
1998: QM Wang; X Luo; A Kheir; Frederick Coffman; George P Studzinski
Retinoblastoma protein-overexpressing HL60 cells resistant to 1,25-dihydroxyvitamin D3 display increased CDK2 and CDK6 activity and shortened G1 phase.
Oncogene 1998;16(21):2729-37.
1998: J Rao; F Zhang; Robert J Donnelly; N L Spector; George P Studzinski
Truncation of Sp1 transcription factor by myeloblastin in undifferentiated HL60 cells.
Journal of cellular physiology 1998;175(2):121-8.
1997: Jeffrey P Gardner; M Balasubramanyam; George P Studzinski
Up-regulation of Ca2+ influx mediated by store-operated channels in HL60 cells induced to differentiate by 1 alpha,25-dihydroxyvitamin D3.
Journal of cellular physiology 1997;172(3):284-95.
1997: Xuening Wang; Nicholas M Ponzio; George P Studzinski
Long-term exposure of HL60 cells to 1,25-dihydroxyvitamin D3 reduces their tumorigenicity: a model for cancer chemoprevention.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;215(4):399-404.
1997: Xuening Wang; George P Studzinski
Antiapoptotic action of 1,25-dihydroxyvitamin D3 is associated with increased mitochondrial MCL-1 and RAF-1 proteins and reduced release of cytochrome c.
Experimental cell research 1997;235(1):210-7.
1997: Xuening Wang; Jeffrey P Gardner; A Kheir; M R Uskokovic; George P Studzinski
Synergistic induction of HL60 cell differentiation by ketoconazole and 1-desoxy analogues of vitamin D3.
Journal of the National Cancer Institute 1997;89(16):1199-206.
1997: QM Wang; X Luo; George P Studzinski
Cyclin-dependent kinase 6 is the principal target of p27/Kip1 regulation of the G1-phase traverse in 1,25-dihydroxyvitamin D3-treated HL60 cells.
Cancer research 1997;57(14):2851-5.
1997: George P Studzinski; B Rathod; QM Wang; J Rao; F Zhang
Uncoupling of cell cycle arrest from the expression of monocytic differentiation markers in HL60 cell variants.
Experimental cell research 1997;232(2):376-87.
1996: Jeffrey P Gardner; F Zhang; M R Uskokovic; George P Studzinski
Vitamin D analog 25-(OH)-16,23E-Diene-26,27-hexafluoro-vitamin D3 induces differentiation of HL60 cells with minimal effects on cellular calcium homeostasis.
Journal of cellular biochemistry 1996;63(4):500-12.
1996: George P Studzinski; B Rathod; J Rao; A Kheir; H J Wajchman; F Zhang; J B Finan; Peter C Nowell
Transition to tetraploidy in 1,25-dihydroxyvitamin D3-resistant HL60 cells is preceded by reduced growth factor dependence and constitutive up-regulation of Sp1 and AP-1 transcription factors.
Cancer research 1996;56(23):5513-21.
1996: F Zhang; B Rathod; J B Jones; QM Wang; Eric J Bernhard; J J Godyn; George P Studzinski
Increased stringency of the 1,25-dihydroxyvitamin D3-induced G1 to S phase block in polyploid HL60 cells.
Journal of cellular physiology 1996;168(1):18-25.
1996: H J Wajchmann; B Rathod; S Song; H Xu; X Wang; M R Uskokovic; George P Studzinski
Loss of deoxcytidine kinase expression and tetraploidization of HL60 cells following long-term culture in 1,25-dihydroxyvitamin D3.
Experimental cell research 1996;224(2):312-22.
1996: QM Wang; J B Jones; George P Studzinski
Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells.
Cancer research 1996;56(2):264-7.
1995: George P Studzinski; D C Moore
Sunlight--can it prevent as well as cause cancer?
Cancer research 1995;55(18):4014-22.
1994: S S Kolla; George P Studzinski
Constitutive DNA binding of the low mobility forms of the AP-1 and SP-1 transcription factors in HL60 cells resistant to 1-beta-D-arabinofuranosylcytosine.
Cancer research 1994;54(6):1418-21.
1994: J J Godyn; H Xu; F Zhang; S Kolla; George P Studzinski
A dual block to cell cycle progression in HL60 cells exposed to analogues of vitamin D3.
Cell proliferation 1994;27(1):37-46.
1993: H M Xu; C G Tepper; J B Jones; C E Fernandez; George P Studzinski
1,25-Dihydroxyvitamin D3 protects HL60 cells against apoptosis but down-regulates the expression of the bcl-2 gene.
Experimental cell research 1993;209(2):367-74.
1993: S S Kolla; George P Studzinski
Resolution of multiple AP-1 complexes in HL-60 cells induced to differentiate by 1,25-dihydroxyvitamin D3.
Journal of cellular physiology 1993;156(1):63-71.
1993: C G Tepper; George P Studzinski
Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death.
Journal of cellular biochemistry 1993;52(3):352-61.
1993: George P Studzinski; J A McLane; M R Uskoković
Signaling pathways for vitamin D-induced differentiation: implications for therapy of proliferative and neoplastic diseases.
Critical reviews in eukaryotic gene expression 1993;3(4):279-312.
1992: H M Xu; S S Kolla; N A Goldenberg; George P Studzinski
Resistance to 1,25-dihydroxyvitamin D3 of a deoxycytidine kinase-deficient variant of human leukemia HL60 cells.
Experimental cell research 1992;203(1):244-50.
1992: C G Tepper; George P Studzinski
Teniposide induces nuclear but not mitochondrial DNA degradation.
Cancer research 1992;52(12):3384-90.
1992: D C Moore; Darryl L Carter; George P Studzinski
Inhibition by 1,25 dihydroxyvitamin D3 of c-myc down-regulation and DNA fragmentation in cytosine arabinoside-induced erythroid differentiation of K562 cells.
Journal of cellular physiology 1992;151(3):539-48.
1992: C G Tepper; M M Pater; A Pater; H M Xu; George P Studzinski
Mitochondrial nucleic acids as internal standards for blot hybridization analyses.
Analytical biochemistry 1992;203(1):127-33.
1991: George P Studzinski; Kaladhar B Reddy; Helene Z Hill; A K Bhandal
Potentiation of 1-beta-D-arabinofuranosylcytosine cytotoxicity to HL-60 cells by 1,25-dihydroxyvitamin D3 correlates with reduced rate of maturation of DNA replication intermediates.
Cancer research 1991;51(13):3451-5.
1991: S S Kolla; D C Moore; George P Studzinski
Vitamin D analogs inhibit erythroid differentiation and induce monocytic differentiation of leukemic cells with the same relative potency.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1991;197(2):214-7.
1991: George P Studzinski; Uma Shankavaram; D C Moore; P V Reddy
Association of c-myc protein with enzymes of DNA replication in high molecular weight fractions from mammalian cells.
Journal of cellular physiology 1991;147(3):412-9.
1991: D C Moore; Darryl L Carter; A K Bhandal; George P Studzinski
Inhibition by 1,25 dihydroxyvitamin D3 of chemically induced erythroid differentiation of K562 leukemia cells.
Blood 1991;77(7):1452-61.
1991: P Pan; Kaladhar B Reddy; S Lee; George P Studzinski
Differentiation-related regulation of 1,25-dihydroxyvitamin D3 receptor mRNA in human leukaemia cells HL-60.
Cell proliferation 1991;24(2):159-70.
1990: J G Satav; Mukund J Modak; George P Studzinski
Photoaffinity labeling of human c-myc protein with deoxythymidine triphosphate.
Laboratory investigation; a journal of technical methods and pathology 1990;63(4):551-6.
1989: George P Studzinski
Oncogenes, growth, and the cell cycle: an overview.
Cell and tissue kinetics 1989;22(6):405-24.
1989: P A Mathew; L K Ellis; George P Studzinski
Enhanced messenger RNA stability and differentiation of HL 60 cells treated with 1,25-dihydroxyvitamin D3 and cordycepin.
Journal of cellular physiology 1989;140(2):212-8.
1987: George P Studzinski; Z S Brelvi
Changes in proto-oncogene expression associated with reversal of macrophage-like differentiation of HL 60 cells.
Journal of the National Cancer Institute 1987;79(1):67-76.
1987: George P Studzinski; Z S Brelvi
Increased expression of oncogene c-Ha-ras during granulocytic differentiation of HL60 cells.
Laboratory investigation; a journal of technical methods and pathology 1987;56(5):499-504.
1987: Z S Brelvi; George P Studzinski
Coordinate expression of c-myc, c-myb, and histone H4 genes in reversibly differentiating HL 60 cells.
Journal of cellular physiology 1987;131(1):43-9.
1986: George P Studzinski; Z S Brelvi; S C Feldman; R A Watt
Participation of c-myc protein in DNA synthesis of human cells.
Science (New York, N.Y.) 1986;234(4775):467-70.
1986: Z S Brelvi; S Christakos; George P Studzinski
Expression of monocyte-specific oncogenes c-fos and c-fms in HL60 cells treated with vitamin D3 analogs correlates with inhibition of DNA synthesis and reduced calmodulin concentration.
Laboratory investigation; a journal of technical methods and pathology 1986;55(3):269-75.
1986: Z S Brelvi; George P Studzinski
Inhibition of DNA synthesis by an inducer of differentiation of leukemic cells, 1 alpha, 25 dihydroxy vitamin D3, precedes down regulation of the c-myc gene.
Journal of cellular physiology 1986;128(2):171-9.
1986: Z S Brelvi; George P Studzinski
Changes in the expression of oncogenes encoding nuclear phosphoproteins but not c-Ha-ras have a relationship to monocytic differentiation of HL 60 cells.
The Journal of cell biology 1986;102(6):2234-43.
1986: George P Studzinski; A K Bhandal; Z S Brelvi
Potentiation by 1-alpha,25-dihydroxyvitamin D3 of cytotoxicity to HL-60 cells produced by cytarabine and hydroxyurea.
Journal of the National Cancer Institute 1986;76(4):641-8.
1985: George P Studzinski; A K Bhandal; Z S Brelvi
Cell cycle sensitivity of HL-60 cells to the differentiation-inducing effects of 1-alpha,25-dihydroxyvitamin D3.
Cancer research 1985;45(8):3898-905.
1985: George P Studzinski; A K Bhandal; Z S Brelvi
A system for monocytic differentiation of leukemic cells HL 60 by a short exposure to 1,25-dihydroxycholecalciferol.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1985;179(3):288-95.