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Kai Stühler

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Steffen Erkelenz; Frank Hillebrand; Marianne Otte; Gereon Poschmann; Anja Stefanski; Kai Stühler; Stephan Theiss; Heiner Schaal
Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.
Heiner Falkenberg; Gesine Kögler; Teja Falk Radke; Kai Stühler
Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood.
L M Dittmann; Jörg Felsberg; Violaine Goidts; J Gronych; M Grzendowski; Peter Lichter; Guido Reifenberger; M C Sabel; Kai Stühler; J Bageritz; S Barbus; N Becker; A Danner; Grischa Toedt; Marietta Wolter; Björn Tews
Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro.

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2013: Steffen Erkelenz; Frank Hillebrand; Marianne Otte; Gereon Poschmann; Anja Stefanski; Kai Stühler; Stephan Theiss; Heiner Schaal
Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.
Journal of virology 2013;87(5):2721-34.
2013: Heiner Falkenberg; Gesine Kögler; Teja Falk Radke; Kai Stühler
Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood.
Stem cells international 2013;2013():245695.
2012: L M Dittmann; Jörg Felsberg; Violaine Goidts; J Gronych; M Grzendowski; Peter Lichter; Guido Reifenberger; M C Sabel; Kai Stühler; J Bageritz; S Barbus; N Becker; A Danner; Grischa Toedt; Marietta Wolter; Björn Tews
Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro.
Oncogene 2012;31(29):3409-18.
2012: J Giebelstein; K Højlund; H Beck-Nielsen; Johannes W. Dietrich; K Levin; H E Meyer; K Podwojski; G Poschmann; Wolfgang Schechinger; Kai Stühler; H H Klein
The proteomic signature of insulin-resistant human skeletal muscle reveals increased glycolytic and decreased mitochondrial enzymes.
Diabetologia 2012;55(4):1114-27.
2012: Barbara Sitek; Helmut E Meyer; Gereon Poschmann; Daniel M Waldera-Lupa; Kai Stühler
Application of label-free proteomics for differential analysis of lung carcinoma cell line A549.
Methods in molecular biology (Clifton, N.J.) 2012;893():241-8.
2012: Gereon Poschmann; Bence Sipos; Barbara Sitek; Kai Stühler
Application of saturation labeling in lung cancer proteomics.
Methods in molecular biology (Clifton, N.J.) 2012;854():253-67.
2011: Sven-T Liffers; Abdelouahid Maghnouj; Johanna B Munding; René Jackstadt; Ulrike Herbrand; Thomas Schulenborg; Katrin Marcus; Susanne Klein-Scory; Wolff Schmiegel; Irmgard Schwarte-Waldhoff; Helmut E Meyer; Kai Stühler; Stephan Hahn
Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε.
BMC cancer 2011;11():137.
2010: Christian Poulsen; Yusuf Akhter; Amy Hye-Won Jeon; Gerold Schmitt-Ulms; Helmut E Meyer; Anja Stefanski; Kai Stühler; Matthias Wilmanns; Young-Hwa Song
Proteome-wide identification of mycobacterial pupylation targets.
Molecular systems biology 2010;6():386.
2010: Bastian Malzkorn; Marietta Wolter; Franziska Liesenberg; Michael Grzendowski; Kai Stühler; Helmut E Meyer; Guido Reifenberger
Identification and functional characterization of microRNAs involved in the malignant progression of gliomas.
Brain pathology (Zurich, Switzerland) 2010;20(3):539-50.
2010: Michael Grzendowski; Marietta Wolter; Markus J Riemenschneider; Christiane B Knobbe; Uwe Schlegel; Helmut E Meyer; Guido Reifenberger; Kai Stühler
Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q.
Neuro-oncology 2010;12(3):243-56.
2010: Stephan Olk; Andrey Turchinovich; Michael Grzendowski; Kai Stühler; Helmut E Meyer; Georg Zoidl; Rolf Dermietzel
Proteomic analysis of astroglial connexin43 silencing uncovers a cytoskeletal platform involved in process formation and migration.
Glia 2010;58(4):494-505.
2010: Susanne Klein-Scory; Salwa Kübler; Hanna Diehl; Christina Eilert-Micus; Anke Reinacher-Schick; Kai Stühler; Bettina Warscheid; Helmut E Meyer; Wolff Schmiegel; Irmgard Schwarte-Waldhoff
Immunoscreening of the extracellular proteome of colorectal cancer cells.
BMC cancer 2010;10():70.
2009: Michael Grzendowski; Markus J Riemenschneider; Eva Hawranke; Anja Stefanski; Helmut E Meyer; Guido Reifenberger; Kai Stühler
Simultaneous extraction of nucleic acids and proteins from tissue specimens by ultracentrifugation: A protocol using the high-salt protein fraction for quantitative proteome analysis.
Proteomics 2009;9(21):4985-90.
2009: Gereon Poschmann; Barbara Sitek; Bence Sipos; Michael Hamacher; Oliver Vonend; Helmut E Meyer; Kai Stühler
Cell-based proteome analysis: the first stage in the pipeline for biomarker discovery.
Biochimica et biophysica acta 2009;1794(9):1309-16.
2009: Jonathan S Minden; Susan R Dowd; Helmut E Meyer; Kai Stühler
Difference gel electrophoresis.
Electrophoresis 2009;30 Suppl 1():S156-61.
2009: Gereon Poschmann; Barbara Sitek; Bence Sipos; Anna Ulrich; Sebastian Wiese; Christian Stephan; Bettina Warscheid; Günter Klöppel; Ann Vander Borght; Frans C S Ramaekers; Helmut E Meyer; Kai Stühler
Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium.
Molecular & cellular proteomics : MCP 2009;8(5):1105-16.
2009: Barbara Sitek; Bence Sipos; Ibrahim Alkatout; Gereon Poschmann; Christian Stephan; Thomas Schulenborg; Katrin Marcus; Jutta Lüttges; Dag-Daniel Dittert; Gustavo Baretton; Wolff Schmiegel; Stephan Hahn; Günter Klöppel; Helmut E Meyer; Kai Stühler
Analysis of the pancreatic tumor progression by a quantitative proteomic approach and immunhistochemical validation.
Journal of proteome research 2009;8(4):1647-56.
2009: Christian Mölleken; Barbara Sitek; Corinna Henkel; Gereon Poschmann; Bence Sipos; Sebastian Wiese; Bettina Warscheid; Christoph Broelsch; Markus Reiser; Scott L Friedman; Ida Tornøe; Anders Schlosser; Günter Klöppel; Wolff Schmiegel; Helmut E Meyer; Uffe Holmskov; Kai Stühler
Detection of novel biomarkers of liver cirrhosis by proteomic analysis.
Hepatology (Baltimore, Md.) 2009;49(4):1257-66.
2009: Anke Walz; Stefan Odenbreit; Kai Stühler; Andreas Wattenberg; Helmut E Meyer; Jafar Mahdavi; Thomas Borén; Stefan Ruhl
Identification of glycoprotein receptors within the human salivary proteome for the lectin-like BabA and SabA adhesins of Helicobacter pylori by fluorescence-based 2-D bacterial overlay.
Proteomics 2009;9(6):1582-92.
2009: Alexander Stang; Elisabeth Petrasch-Parwez; Sabine Brandt; Rolf Dermietzel; Helmut E Meyer; Kai Stühler; Sven-T Liffers; Klaus Uberla; Thomas Grunwald
Unintended spread of a biosafety level 2 recombinant retrovirus.
Retrovirology 2009;6():86.
2008: Sebastian A Potthoff; Barbara Sitek; Johannes Stegbauer; Thomas Schulenborg; Katrin Marcus; Ivo Quack; Lars C Rump; Helmut E Meyer; Kai Stühler; Oliver Vonend
The glomerular proteome in a model of chronic kidney disease.
Proteomics. Clinical applications 2008;2(7-8):1127-39.
2008: Barbara Sitek; B Sipos; Kathy Pfeiffer; M Grzendowski; G Poschmann; E Hawranke; K Köper; Günter Klöppel; Helmut E Meyer; Kai Stühler
Establishment of "one-piece" large-gel 2-DE for high-resolution analysis of small amounts of sample using difference gel electrophoresis saturation labelling.
Analytical and bioanalytical chemistry 2008;391(1):361-5.
2008: Jon Barbour; Eva M Neuhaus; Heike Piechura; Nadine Stoepel; Anastasia Mashukova; Daniela Brunert; Barbara Sitek; Kai Stühler; Helmut E Meyer; Hanns Hatt; Bettina Warscheid
New insight into stimulus-induced plasticity of the olfactory epithelium in Mus musculus by quantitative proteomics.
Journal of proteome research 2008;7(4):1594-605.
2008: Barbara Sitek; Bence Sipos; Günter Klöppel; Wolff Schmiegel; Stephan Hahn; Helmut E Meyer; Kai Stühler
Application of fluorescence dye saturation labeling for differential proteome analysis of 1,000 microdissected cells from pancreatic ductal adenocarcinoma precursor lesions.
Methods in molecular biology (Clifton, N.J.) 2008;425():1-14.
2008: Romano Hebeler; Silke Oeljeklaus; Kai A Reidegeld; Martin Eisenacher; Christian Stephan; Barbara Sitek; Kai Stühler; Helmut E Meyer; Marcel J G Sturre; Paul P Dijkwel; Bettina Warscheid
Study of early leaf senescence in Arabidopsis thaliana by quantitative proteomics using reciprocal 14N/15N labeling and difference gel electrophoresis.
Molecular & cellular proteomics : MCP 2008;7(1):108-20.
2007: Helmut E Meyer; Kai Stühler
High-performance proteomics as a tool in biomarker discovery.
Proteomics 2007;7 Suppl 1():18-26.
2007: Hanna C Diehl; Kai Stühler; Susanne Klein-Scory; Martin W Volmer; Anna Schöneck; Cornelia Bieling; Wolff Schmiegel; Helmut E Meyer; Irmgard Schwarte-Waldhoff
A catalogue of proteins released by colorectal cancer cells in vitro as an alternative source for biomarker discovery.
Proteomics. Clinical applications 2007;1(1):47-61.
2006: Corinna Henkel; Martin Roderfeld; Ralf Weiskirchen; Marie-Luise Berres; Sonja Hillebrandt; Frank Lammert; Helmut E Meyer; Kai Stühler; Jürgen Graf; Elke Roeb
Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis.
Proteomics 2006;6(24):6538-48.
2006: Kai Stühler; Katharina Köper; Kathy Pfeiffer; Andreas Tagariello; Manfred Souquet; Irmgard Schwarte-Waldhoff; Stephan Hahn; Wolff Schmiegel; Helmut E Meyer
Differential proteome analysis of colon carcinoma cell line SW480 after reconstitution of the tumour suppressor Smad4.
Analytical and bioanalytical chemistry 2006;386(6):1603-12.
2006: Kai Stühler; Kathy Pfeiffer; Cornelia Joppich; Christian Stephan; Klaus Jung; Michael Müller; Oliver Schmidt; Andre van Hall; Michael Hamacher; Wolfgang Urfer; Helmut E Meyer; Katrin Marcus
Pilot study of the Human Proteome Organisation Brain Proteome Project: applying different 2-DE techniques to monitor proteomic changes during murine brain development.
Proteomics 2006;6(18):4899-913.
2006: Barbara Sitek; Sebastian Potthoff; Thomas Schulenborg; Johannes Stegbauer; Tobias Vinke; Lars Christian Rump; Helmut E Meyer; Oliver Vonend; Kai Stühler
Novel approaches to analyse glomerular proteins from smallest scale murine and human samples using DIGE saturation labelling.
Proteomics 2006;6(15):4337-45.
2006: Anke Walz; Kai Stühler; Andreas Wattenberg; Eva Hawranke; Helmut E Meyer; Gottfried Schmalz; Martin Blüggel; Stefan Ruhl
Proteome analysis of glandular parotid and submandibular-sublingual saliva in comparison to whole human saliva by two-dimensional gel electrophoresis.
Proteomics 2006;6(5):1631-9.
2005: Barbara Sitek; Jutta Lüttges; Katrin Marcus; Günter Klöppel; Wolff Schmiegel; Helmut E Meyer; Stephan Hahn; Kai Stühler
Application of fluorescence difference gel electrophoresis saturation labelling for the analysis of microdissected precursor lesions of pancreatic ductal adenocarcinoma.
Proteomics 2005;5(10):2665-79.
2005: Martin W Volmer; Kai Stühler; Marc Zapatka; Anna Schöneck; Susanne Klein-Scory; Wolff Schmiegel; Helmut E Meyer; Irmgard Schwarte-Waldhoff
Differential proteome analysis of conditioned media to detect Smad4 regulated secreted biomarkers in colon cancer.
Proteomics 2005;5(10):2587-601.
2005: Barbara Sitek; Ognjan Apostolov; Kai Stühler; Kathy Pfeiffer; Helmut E Meyer; Angelika Eggert; Alexander Schramm
Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry.
Molecular & cellular proteomics : MCP 2005;4(3):291-9.
2004: Kai Stühler; Helmut E Meyer
MALDI: more than peptide mass fingerprints.
Current opinion in molecular therapeutics 2004;6(3):239-48.
2004: Martin W Volmer; Yvonne Radacz; Stephan Hahn; Susanne Klein-Scory; Kai Stühler; Marc Zapatka; Wolff Schmiegel; Helmut E Meyer; Irmgard Schwarte-Waldhoff
Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a "secretome" analysis.
Proteomics 2004;4(5):1324-34.
2004: Daniel C Chamrad; Gerhard Körting; Kai Stühler; Helmut E Meyer; Joachim Klose; Martin Blüggel
Evaluation of algorithms for protein identification from sequence databases using mass spectrometry data.
Proteomics 2004;4(3):619-28.
2003: Alexander Schramm; Ognjan Apostolov; Barbara Sitek; Kathy Pfeiffer; Kai Stühler; H E Meyer; Werner Havers; Angelika Eggert
Proteomics: techniques and applications in cancer research.
Klinische Pädiatrie 2003;215(6):293-7.
2002: Joachim Klose; Christina Nock; Marion Herrmann; Kai Stühler; Katrin Marcus; Martin Blüggel; Eberhard Krause; Leonard C Schalkwyk; Sohaila Rastan; Steve D M Brown; Konrad Büssow; Heinz Himmelbauer; Hans Lehrach
Genetic analysis of the mouse brain proteome.
Nature genetics 2002;30(4):385-93.