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Richard Sturm

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TOP 3
Kimberley A Beaumont; Eric Chai; Yan Yan Liu; Glenn L Millhauser; Mira P Patel; Darren J Smit; Jennifer J Smith; Paul F Alewood; Richard A Sturm
Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands.
Shu-Shyan Wong; Stephen A Ainger; J Helen Leonard; Richard A Sturm
MC1R variant allele effects on UVR-induced phosphorylation of p38, p53, and DDB2 repair protein responses in melanocytic cells in culture.
Richard A Sturm; David L Duffy
Human pigmentation genes under environmental selection.

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2012: Kimberley A Beaumont; Eric Chai; Yan Yan Liu; Glenn L Millhauser; Mira P Patel; Darren J Smit; Jennifer J Smith; Paul F Alewood; Richard A Sturm
Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands.
Pigment cell & melanoma research 2012;25(3):370-4.
2012: Shu-Shyan Wong; Stephen A Ainger; J Helen Leonard; Richard A Sturm
MC1R variant allele effects on UVR-induced phosphorylation of p38, p53, and DDB2 repair protein responses in melanocytic cells in culture.
The Journal of investigative dermatology 2012;132(5):1452-61.
2012: Richard A Sturm; David L Duffy
Human pigmentation genes under environmental selection.
Genome biology 2012;13(9):248.
2011: Mats Larsson; Jimmy Z Liu; Stuart Macgregor; David A Mackey; Nicholas G Martin; Allan F McRae; Grant W Montgomery; Richard A Sturm; Margaret J Wright; Gu Zhu; David L Duffy; Sarah E Medland
GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development.
American journal of human genetics 2011;89(2):334-43.
2011: Stephen A Ainger; J Helen Leonard; Donald W Roberts; Shu S Wong; Richard A Sturm
Effect of MC1R variant allele status on MSH-ligand induction of dopachrome tautomerase in melanocytes co-cultured with keratinocytes.
Experimental dermatology 2011;20(8):681-4.
2011: A E Thurber; S E Zabierowski; G Douglas; E Hacker; Meenhard Herlyn; J Helen Leonard; S N Ramakrishnan; Darren J Smit; E C Sturm; Richard A Sturm
Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway.
Oncogene 2011;30(27):3036-48.
2011: Kimberley A Beaumont; Shu S Wong; Stephen A Ainger; Yan Yan Liu; Mira P Patel; Glenn L Millhauser; Jennifer J Smith; Paul F Alewood; J Helen Leonard; Richard A Sturm
Melanocortin MC₁ receptor in human genetics and model systems.
European journal of pharmacology 2011;660(1):103-10.
2011: Glen M Boyle; Anthony L Cook; Ken Dutton-Regester; Elke Hacker; Lauren G Aoude; Vanessa F Bonazzi; Mitchell S Stark; Richard A Sturm; Susan L Woods; Nicholas K Hayward
Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor.
Pigment cell & melanoma research 2011;24(3):525-37.
2011: Aaron G Smith; Wen Lim; Michael Pearen; George E O Muscat; Richard A Sturm
Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells.
Pigment cell & melanoma research 2011;24(3):551-63.
2011: Puya Gharahkhani; MT Kyaw-Tanner; CA O'Leary; Richard A Sturm; David L Duffy
A non-synonymous mutation in the canine Pkd1 gene is associated with autosomal dominant polycystic kidney disease in Bull Terriers.
PloS one 2011;6(7):e22455.
2010: David L Duffy; Mark M Iles; Dan Glass; Gu Zhu; Jennifer H Barrett; Veronica Höiom; Zhen Zhen Zhao; Richard A Sturm; Nicole Soranzo; Chris Hammond; Marina Kvaskoff; David C Whiteman; Massimo Mangino; Johan Hansson; Julia Newton-Bishop; Veronique Bataille; Nicholas K Hayward; Nicholas G Martin; D Timothy Bishop; Timothy D Spector; Grant W Montgomery
IRF4 variants have age-specific effects on nevus count and predispose to melanoma.
American journal of human genetics 2010;87(1):6-16.
2010: Aaron G Smith; Richard A Sturm
Multiple genes and locus interactions in susceptibility to vitiligo.
The Journal of investigative dermatology 2010;130(3):643-5.
2010: Helene C Johanson; Wei Chen; Carol Wicking; Richard A Sturm
Inheritance of a novel mutated allele of the OCA2 gene associated with high incidence of oculocutaneous albinism in a Polynesian community.
Journal of human genetics 2010;55(2):103-11.
2010: David L Duffy; Zhen Z Zhao; Richard A Sturm; Nicholas K Hayward; Nicholas G Martin; Grant W Montgomery
Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.
The Journal of investigative dermatology 2010;130(2):520-8.
2010: Mitchell S Stark; Sonika Tyagi; Derek J Nancarrow; Glen M Boyle; Anthony L Cook; David C Whiteman; Peter G Parsons; Christopher Schmidt; Richard A Sturm; Nicholas K Hayward
Characterization of the Melanoma miRNAome by Deep Sequencing.
PloS one 2010;5(3):e9685.
2009: Richard A Sturm; Mats Larsson
Genetics of human iris colour and patterns.
Pigment cell & melanoma research 2009;22(5):544-62.
2009: Richard A Sturm
Molecular genetics of human pigmentation diversity.
Human molecular genetics 2009;18(R1):R9-17.
2009: Aaron G Smith; Kimberley A Beaumont; Darren J Smit; Amy E Thurber; Anthony L Cook; Glen M Boyle; Peter G Parsons; Richard A Sturm; George E O Muscat
PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.
The international journal of biochemistry & cell biology 2009;41(4):844-52.
2009: Anthony L Cook; Wei Chen; Amy E Thurber; Darren J Smit; Aaron G Smith; Timothy G Bladen; Darren L Brown; David L Duffy; Lorenza Pastorino; Giovanna Bianchi-Scarra; J Helen Leonard; Jennifer L Stow; Richard A Sturm
Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci.
The Journal of investigative dermatology 2009;129(2):392-405.
2008: Anthony L Cook; Richard A Sturm
POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis.
Pigment cell & melanoma research 2008;21(6):611-26.
2008: Kimberley A Beaumont; Sri N Shekar; Anthony L Cook; David L Duffy; Richard A Sturm
Red hair is the null phenotype of MC1R.
Human mutation 2008;29(8):E88-94.
2008: Aaron G Smith; Nicole Luk; Richard A Newton; Donald W Roberts; Richard A Sturm; George E O Muscat
Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells.
The Journal of biological chemistry 2008;283(18):12564-70.
2008: Donald W Roberts; Richard A Newton; J Helen Leonard; Richard A Sturm
Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.
Journal of cellular physiology 2008;215(2):344-55.
2008: Richard A Sturm; David L Duffy; Zhen Zhen Zhao; Fabio P N Leite; Mitchell S Stark; Nicholas K Hayward; Nicholas G Martin; Grant W Montgomery
A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color.
American journal of human genetics 2008;82(2):424-31.
2007: Darren J Smit; brooke gardiner; Richard A Sturm
Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype.
International journal of cancer. Journal international du cancer 2007;121(12):2653-60.
2007: Richard A Newton; Donald W Roberts; J Helen Leonard; Richard A Sturm
Human melanocytes expressing MC1R variant alleles show impaired activation of multiple signaling pathways.
Peptides 2007;28(12):2387-96.
2007: Donald W Roberts; Richard A Newton; Richard A Sturm
MC1R expression in skin: is it confined to melanocytes?
The Journal of investigative dermatology 2007;127(10):2472-3.
2007: Kimberley A Beaumont; Sri N Shekar; Sri L Shekar; Richard A Newton; Michael R James; Jennifer L Stow; David L Duffy; Richard A Sturm
Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles.
Human molecular genetics 2007;16(18):2249-60.
2007: Richard A Newton; Anthony L Cook; Donald W Roberts; J Helen Leonard; Richard A Sturm
Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes.
The Journal of investigative dermatology 2007;127(9):2216-27.
2007: David L Duffy; Grant W Montgomery; Wei Chen; Zhen Zhen Zhao; Lien Le; Michael R James; Nicholas K Hayward; Nicholas G Martin; Richard A Sturm
A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation.
American journal of human genetics 2007;80(2):241-52.
2006: Richard A Sturm
A golden age of human pigmentation genetics.
Trends in genetics : TIG 2006;22(9):464-8.
2006: Joanne Voisey; M Del C Gomez-Cabrera; Darren J Smit; J Helen Leonard; Richard A Sturm; Angela van Daal
A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(3):226-31.
2006: Donald W Roberts; Richard A Newton; Kimberley A Beaumont; J Helen Leonard; Richard A Sturm
Quantitative analysis of MC1R gene expression in human skin cell cultures.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(1):76-89.
2005: Richard A Newton; Sonia E Smit; Christopher C Barnes; Julie Pedley; Peter G Parsons; Richard A Sturm
Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells.
Peptides 2005;26(10):1818-24.
2005: Kimberley A Beaumont; Richard A Newton; Darren J Smit; J Helen Leonard; Jennifer L Stow; Richard A Sturm
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk.
Human molecular genetics 2005;14(15):2145-54.
2005: Anthony L Cook; Aaron G Smith; Darren J Smit; J Helen Leonard; Richard A Sturm
Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.
Experimental cell research 2005;308(1):222-35.
2005: Richard A Sturm
Osteopontin in melanocytic lesions--a first step towards invasion?
The Journal of investigative dermatology 2005;124(5):xiv-xv.
2004: Richard A Sturm; Tony N Frudakis
Eye colour: portals into pigmentation genes and ancestry.
Trends in genetics : TIG 2004;20(8):327-32.
2004: Gu Zhu; David M Evans; David L Duffy; Grant W Montgomery; Sarah E Medland; Nathan A Gillespie; Kelly R Ewen; Mary Jewell; Yew Wah Liew; Nicholas K Hayward; Richard A Sturm; Jeffrey M. Trent; Nicholas G Martin
A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q.
Twin research : the official journal of the International Society for Twin Studies 2004;7(2):197-210.
2004: David L Duffy; Neil Box; Wei Chen; James S Palmer; Grant W Montgomery; Michael R James; Nicholas K Hayward; Nicholas G Martin; Richard A Sturm
Interactive effects of MC1R and OCA2 on melanoma risk phenotypes.
Human molecular genetics 2004;13(4):447-61.
2003: Anthony L Cook; Philippe D Donatien; Aaron G Smith; Mark Murphy; Malcolm K Jones; Meenhard Herlyn; Dorothy C Bennett; J Helen Leonard; Richard A Sturm
Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3.
The Journal of investigative dermatology 2003;121(5):1150-9.
2003: Richard A Sturm; David L Duffy; Neil Box; Richard A Newton; A G Shepherd; Wei Chen; Lisa H Marks; J Helen Leonard; Nicholas G Martin
Genetic association and cellular function of MC1R variant alleles in human pigmentation.
Annals of the New York Academy of Sciences 2003;994():348-58.
2003: Richard A Sturm; David L Duffy; Neil Box; Wei Chen; Darren J Smit; Darren L Brown; Jennifer L Stow; J Helen Leonard; Nicholas G Martin
The role of melanocortin-1 receptor polymorphism in skin cancer risk phenotypes.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2003;16(3):266-72.
2003: J Helen Leonard; Lisa H Marks; Wei Chen; Anthony L Cook; Glen M Boyle; Darren J Smit; Darren L Brown; Jennifer L Stow; Peter G Parsons; Richard A Sturm
Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2003;16(3):198-207.
2002: Richard A Sturm
Skin colour and skin cancer - MC1R, the genetic link.
Melanoma research 2002;12(5):405-16.
2002: J Helen Leonard; Anthony L Cook; Mireille Van Gele; Glen M Boyle; Kelly J Inglis; Frank Speleman; Richard A Sturm
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.
International journal of cancer. Journal international du cancer 2002;101(2):103-10.
2002: Richard A Sturm; Kapaettu Satyamoorthy; Friedegund Meier; brooke gardiner; Darren J Smit; Bhavesh Vaidya; Meenhard Herlyn
Osteonectin/SPARC induction by ectopic beta(3) integrin in human radial growth phase primary melanoma cells.
Cancer research 2002;62(1):226-32.
2001: Aaron G Smith; Neil Box; Lisa H Marks; Wei Chen; Darren J Smit; JR Wyeth; Gavin A Huttley; Simon Easteal; Richard A Sturm
The human melanocortin-1 receptor locus: analysis of transcription unit, locus polymorphism and haplotype evolution.
Gene 2001;281(1-2):81-94.
2001: Richard A Sturm; Rohan Teasdale; Neil Box
Human pigmentation genes: identification, structure and consequences of polymorphic variation.
Gene 2001;277(1-2):49-62.
2001: Neil Box; David L Duffy; Wei Chen; M Stark; Nicholas G Martin; Richard A Sturm; Nicholas K Hayward
MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations.
American journal of human genetics 2001;69(4):765-73.
2001: Neil Box; David L Duffy; R E Irving; Anne Russell; Wei Chen; L R Griffyths; Peter G Parsons; Adèle C Green; Richard A Sturm
Melanocortin-1 receptor genotype is a risk factor for basal and squamous cell carcinoma.
The Journal of investigative dermatology 2001;116(2):224-9.
2000: Darren J Smit; Aaron G Smith; Peter G Parsons; George E O Muscat; Richard A Sturm
Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors.
European journal of biochemistry / FEBS 2000;267(21):6413-22.
2000: James S Palmer; David L Duffy; Neil Box; Joanne F Aitken; Louise E O'Gorman; Adèle C Green; Nicholas K Hayward; Nicholas G Martin; Richard A Sturm
Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?
American journal of human genetics 2000;66(1):176-86.
2000: L Qiu; M Zhang; Richard A Sturm; brooke gardiner; Ian D Tonks; G Kay; Peter G Parsons
Inhibition of melanin synthesis by cystamine in human melanoma cells.
The Journal of investigative dermatology 2000;114(1):21-7.
1998: Richard A Sturm
Human pigmentation genes and their response to solar UV radiation.
Mutation research 1998;422(1):69-76.
1998: Effie Ablett; Julie Pedley; P A Dannoy; Richard A Sturm; Peter G Parsons
UVB-specific regulation of gene expression in human melanocytic cells: cell cycle effects and implication in the generation of melanoma.
Mutation research 1998;422(1):31-41.
1998: Richard A Sturm; Neil Box; Michele Ramsay
Human pigmentation genetics: the difference is only skin deep.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(9):712-21.
1998: Aaron G Smith; G Brightwell; S E Smit; Peter G Parsons; Richard A Sturm
Redox regulation of Brn-2/N-Oct-3 POU domain DNA binding activity and proteolytic formation of N-Oct-5 during melanoma cell nuclear extraction.
Melanoma research 1998;8(1):2-10.
1998: Neil Box; JR Wyeth; C J Mayne; Louise E O'Gorman; Nicholas G Martin; Richard A Sturm
Complete sequence and polymorphism study of the human TYRP1 gene encoding tyrosinase-related protein 1.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(1):50-3.
1997: Pravin Manga; Jennifer Kromberg; Neil Box; Richard A Sturm; Trefor Jenkins; Michele Ramsay
Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene.
American journal of human genetics 1997;61(5):1095-101.
1997: Neil Box; JR Wyeth; Louise E O'Gorman; Nicholas G Martin; Richard A Sturm
Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair.
Human molecular genetics 1997;6(11):1891-7.
1997: Peter G Parsons; C Hansen; David P Fairlie; ML West; P A Danoy; Richard A Sturm; I S Dunn; Julie Pedley; Effie Ablett
Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells.
Biochemical pharmacology 1997;53(11):1719-24.
1997: C Hansen; Effie Ablett; A Green; Richard A Sturm; I S Dunn; David P Fairlie; ML West; Peter G Parsons
Biphasic response of the metallothionein promoter to ultraviolet radiation in human melanoma cells.
Photochemistry and photobiology 1997;65(3):550-5.
1997: Suzanne M Cutts; A Masta; C Panousis; P G Parsons; Richard A Sturm; Don R Phillips
A gel mobility shift assay for probing the effect of drug-DNA adducts on DNA-binding proteins.
Methods in molecular biology (Clifton, N.J.) 1997;90():95-106.
1996: Julie Pedley; Effie Ablett; A Pettit; J Meyer; I S Dunn; Richard A Sturm; Peter G Parsons
Inhibition of retinoblastoma protein translation by UVB in human melanocytic cells and reduced cell cycle arrest following repeated irradiation.
Oncogene 1996;13(6):1335-42.
1995: Richard A Sturm; B J O'Sullivan; Neil Box; A G Smith; S E Smit; E R Puttick; Peter G Parsons; I S Dunn
Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family.
Genomics 1995;29(1):24-34.
1995: J A Thomson; K Murphy; E Baker; G R Sutherland; Peter G Parsons; Richard A Sturm; F Thomson
The brn-2 gene regulates the melanocytic phenotype and tumorigenic potential of human melanoma cells.
Oncogene 1995;11(4):691-700.
1995: Richard A Sturm; H J Eyre; E Baker; G R Sutherland
The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23.
Cytogenetics and cell genetics 1995;68(3-4):231-2.
1994: Dennis H Dowhan; Meredith Downes; Richard A Sturm; George E O Muscat
Identification of deoxyribonucleic acid sequences that bind retinoid-X receptor-gamma with high affinity.
Endocrinology 1994;135(6):2595-607.
1994: Neil Box; Richard A Sturm
Dinucleotide repeat polymorphism at the human TYRP1 locus.
Human molecular genetics 1994;3(12):2270.
1994: Richard A Sturm; B J O'Sullivan; J A Thomson; N Jamshidi; Julie Pedley; Peter G Parsons
Expression studies of pigmentation and POU-domain genes in human melanoma cells.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1994;7(4):235-40.
1994: J A Thomson; J H Leonard; K McGregor; Richard A Sturm; Peter G Parsons
A nonconsensus octamer-recognition sequence (TAATGARAT-motif) identifies a novel DNA binding protein in human Merkel cell carcinoma cell lines.
International journal of cancer. Journal international du cancer 1994;58(2):285-90.
1994: G A Fechner; J Michel; Richard A Sturm; J J Jacobs; Peter G Parsons
Reduction of DNA synthesis, pigment synthesis, pigmentation gene mRNA and resistance to UVB in human melanoma cells treated with analogues of a histamine (H2) agonist.
Biochemical pharmacology 1994;48(1):121-30.
1994: J L Cassady; Richard A Sturm
Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA.
Gene 1994;143(2):295-8.
1994: Richard A Sturm; E Baker; G R Sutherland
Assignment of the tyrosinase-related protein-2 gene (TYRP2) to human chromosome 13q31-q32 by fluorescence in situ hybridization: extended synteny with mouse chromosome 14.
Genomics 1994;21(1):293-6.
1994: R W Slade; P T Hale; D I Francis; J A Graves; Richard A Sturm
The marsupial MHC: the tammar wallaby, Macropus eugenii, contains an expressed DNA-like gene on chromosome 1.
Journal of molecular evolution 1994;38(5):496-505.
1994: S S Wong; Richard A Sturm; J Michel; X M Zhang; P A Danoy; K McGregor; J J Jacobs; A Kaushal; Y Dong; I S Dunn
Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells.
Biochemical pharmacology 1994;47(5):827-37.
1994: Richard A Sturm; D I Francis; J L Cassady; J A Graves
Identification of a marsupial OTF1 gene: cross-species STS analysis and in situ cross-hybridization to Macropus eugenii chromosomes 3/4 and 5.
Cytogenetics and cell genetics 1994;65(4):272-5.
1993: A J Bendall; Richard A Sturm; P A Danoy; Peter Molloy
Broad binding-site specificity and affinity properties of octamer 1 and brain octamer-binding proteins.
European journal of biochemistry / FEBS 1993;217(3):799-811.
1993: Richard A Sturm; J L Cassady; G Das; A Romo; G A Evans
Chromosomal structure and expression of the human OTF1 locus encoding the Oct-1 protein.
Genomics 1993;16(2):333-41.
1993: J A Thomson; Peter G Parsons; Richard A Sturm
In vivo and in vitro expression of octamer binding proteins in human melanoma metastases, brain tissue, and fibroblasts.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1993;6(1):13-22.
1991: Richard A Sturm
An STS in the human oct-1 gene located on chromosome 1.
Nucleic acids research 1991;19(24):6963.
1991: C E Zevering; Craig Moritz; A Heideman; Richard A Sturm
Parallel origins of duplications and the formation of pseudogenes in mitochondrial DNA from parthenogenetic lizards (Heteronotia binoei; Gekkonidae).
Journal of molecular evolution 1991;33(5):431-41.
1991: Richard A Sturm; F Bisshop; H Takahashi; Peter G Parsons
A melanoma octamer binding protein is responsive to differentiating agents.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(10):519-24.