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Ezio Bombardelli
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32
Morazzoni, Paolo
23
Riva, Antonella
18
Scambia, Giovanni
17
Ferlini, Cristiano
14
Mancuso, Salvatore
14
Fontana, Gabriele
10
Gallo, Daniela
10
Battaglia, Arturo
10
Zunino, Franco
9
Distefano, Mariagrazia
8
Appendino, Giovanni
7
Gessa, Gian Luigi
7
Guerrini, Andrea
7
Zucchetti, Massimo
7
Riva, Antonella
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All Publications
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2009: Fantini Noemi; Cabras Claudia; Lobina Carla; Colombo Giancarlo; Gessa Gian Luigi; Riva Antonella; Donzelli Fabio; Morazzoni Paolo; Bombardelli Ezio; Carai Mauro A M
Reducing effect of a Phaseolus vulgaris dry extract on food intake, body weight, and glycemia in rats.
Journal of agricultural and food chemistry 2009;57(19):9316-23.
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2009: Pepe Antonella; Sun Liang; Zanardi Ilaria; Wu Xinyuan; Ferlini Cristiano; Fontana Gabriele; Bombardelli Ezio; Ojima Iwao
Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin.
Bioorganic & medicinal chemistry letters 2009;19(12):3300-4.
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2009: Samorì Cristian; Guerrini Andrea; Varchi Greta; Beretta Giovanni Luca; Fontana Gabriele; Bombardelli Ezio; Carenini Nives; Zunino Franco; Bertucci Carlo; Fiori Jessica; Battaglia Arturo
The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates.
Bioconjugate chemistry 2009;20(3):629.
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2009: Samorì Cristian; Guerrini Andrea; Varchi Greta; Fontana Gabriele; Bombardelli Ezio; Tinelli Stella; Beretta Giovanni Luca; Basili Serena; Moro Stefano; Zunino Franco; Battaglia Arturo
Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.
Journal of medicinal chemistry 2009;52(4):1029-39.
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2009: Artali Roberto; Beretta Giangiacomo; Morazzoni Paolo; Bombardelli Ezio; Meneghetti Fiorella
Green tea catechins in chemoprevention of cancer: a molecular docking investigation into their interaction with glutathione S-transferase (GST P1-1).
Journal of enzyme inhibition and medicinal chemistry 2009;24(1):287-95.
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2008: Samor Cristian; Guerrini Andrea; Varchi Greta; Beretta Giovanni Luca; Fontana Gabriele; Bombardelli Ezio; Carenini Nives; Zunino Franco; Bertucci Carlo; Fiori Jessica; Battaglia Arturo
The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates.
Bioconjugate chemistry 2008;19(11):2270-9.
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2008: Samorì Cristian; Guerrini Andrea; Varchi Greta; Zunino Franco; Beretta Giovanni Luca; Femoni Cristina; Bombardelli Ezio; Fontana Gabriele; Battaglia Arturo
Thiocamptothecin.
Journal of medicinal chemistry 2008;51(10):3040-4.
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2008: Steigerwalt Robert D; Gianni Belcaro; Paolo Morazzoni; Bombardelli Ezio; Burki Carolina; Schönlau Frank
Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects.
Molecular vision 2008;14():1288-92.
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2007: Gelmi Maria Luisa; Fontana Gabriele; Pocar Donato; Pontremoli Guido; Pellegrino Sara; Bombardelli Ezio; Riva Antonella; Balduini Walter; Carloni Silvia; Cimino Mauro
Novel 3-O-glycosyl-3-demethylthiocolchicines as ligands for glycine and gamma-aminobutyric acid receptors.
Journal of medicinal chemistry 2007;50(9):2245-8.
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2007: Botta Maurizio; Armaroli Silvia; Castagnolo Daniele; Fontana Gabriele; Pera Paula; Bombardelli Ezio
Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J.
Bioorganic & medicinal chemistry letters 2007;17(6):1579-83.
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2007: Verotta Luisella; Appendino Giovanni; Bombardelli Ezio; Brun Reto
In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study.
Bioorganic & medicinal chemistry letters 2007;17(6):1544-8.
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2006: Beretta Giovanni L; Petrangolini Giovanna; De Cesare Michelandrea; Pratesi Graziella; Perego Paola; Tinelli Stella; Tortoreto Monica; Zucchetti Massimo; Frapolli Roberta; Bello Ezia; Manzotti Carla; Fontana Gabriele; Bombardelli Ezio; Battaglia Arturo; Samorì Cristian; Zunino Franco
Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
Cancer research 2006;66(22):10976-82.
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2006: Gelmi Maria Luisa; Pocar Donato; Pontremoli Guido; Pellegrino Sara; Bombardelli Ezio; Fontana Gabriele; Riva Antonella; Balduini Walter; Carloni Silvia; Cimino Mauro; Johnson Francis
3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds.
Journal of medicinal chemistry 2006;49(18):5571-7.
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2006: Colombo Giancarlo; Serra Salvatore; Vacca Giovanni; Orrù Alessandro; Maccioni Paola; Morazzoni Paolo; Bombardelli Ezio; Riva Antonella; Gessa Gian Luigi; Carai Mauro A M
Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats.
Alcoholism, clinical and experimental research 2006;30(5):754-62.
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2006: Mauri Pierluigi; De Palma Antonella; Pozzi Francesca; Basilico Fabrizio; Riva Antonella; Morazzoni Paolo; Bombardelli Ezio; Rossoni Giuseppe
LC-MS characterization of terpene lactones in plasma of experimental animals treated with Ginkgo biloba extracts Correlation with pharmacological activity.
Journal of pharmaceutical and biomedical analysis 2006;40(3):763-8.
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2006: Gallo Daniela; Zannoni Gian Franco; Martinelli Enrica; Ferlini Cristiano; Fabrizi Manuela; Riva Antonella; Morazzoni Paolo; Bombardelli Ezio; Scambia Giovanni
Estradiol and phytoestrogens differently influence the rodent postmenopausal mammary gland.
Menopause (New York, N.Y.) 2006;13(1):72-9.
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2005: Barboni Luciano; Ballini Roberto; Giarlo Guido; Appendino Giovanni; Fontana Gabriele; Bombardelli Ezio
Synthesis and biological evaluation of methoxylated analogs of the newer generation taxoids IDN5109 and IDN5390.
Bioorganic & medicinal chemistry letters 2005;15(23):5182-6.
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2005: Varchi Greta; Battaglia Arturo; Samorì Cristian; Baldelli Eleonora; Danieli Bruno; Fontana Gabriele; Guerrini Andrea; Bombardelli Ezio
Synthesis of deserpidine from reserpine.
Journal of natural products 2005;68(11):1629-31.
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2005: Gallo Daniela; Zannoni Gian Franco; Apollonio Patrizia; Martinelli Enrica; Ferlini Cristiano; Passetti Gianluigi; Riva Antonella; Morazzoni Paolo; Bombardelli Ezio; Scambia Giovanni
Characterization of the pharmacologic profile of a standardized soy extract in the ovariectomized rat model of menopause: effects on bone, uterus, and lipid profile.
Menopause (New York, N.Y.) 2005;12(5):589-600.
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2005: Song Liguo; Prey Joshua D; Xue Jun; Kanter Peter; Manzotti Carla; Bombardelli Ezio; Morazzoni Paulo; Pendyala Lakshmi
Pharmacokinetic measurements of IDN 5390 using electrospray ionization tandem mass spectrometry: structure characterization and quantification in dog plasma.
Rapid communications in mass spectrometry : RCM 2005;19(24):3617-25.
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2004: Verotta Luisella; Lovaglio Erminio; Sterner Olov; Appendino Giovanni; Bombardelli Ezio
Modulation of chemoselectivity by protein additives. Remarkable effects in the oxidation of hyperforin.
The Journal of organic chemistry 2004;69(23):7869-74.
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2004: Verotta Luisella; Lovaglio Erminio; Vidari Giovanni; Finzi Paola Vita; Neri Maria Grazia; Raimondi Alessandro; Parapini Silvia; Taramelli Donatella; Riva Antonella; Bombardelli Ezio
4-Alkyl- and 4-phenylcoumarins from Mesua ferrea as promising multidrug resistant antibacterials.
Phytochemistry 2004;65(21):2867-79.
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2004: Baldelli Eleonora; Battaglia Arturo; Bombardelli Ezio; Carenzi Giacomo; Fontana Gabriele; Gelmi Maria Luisa; Guerrini Andrea; Pocar Donato
New taxane derivatives: synthesis of baccatin[14,1-d]furan-2-one nucleus and its condensation with the norstatine side chain.
The Journal of organic chemistry 2004;69(20):6610-6.
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2004: Danieli Bruno; Giardini Alessandra; Lesma Giordano; Passarella Daniele; Silvani Alessandra; Appendino Giovanni; Noncovich Alain; Fontana Gabriele; Bombardelli Ezio; Sterner Olov
Synthesis and biological evaluation of paclitaxel-thiocolchicine hybrids.
Chemistry & biodiversity 2004;1(2):327-45.
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2004: Appendino Giovanni; Bettoni Piergiorgio; Noncovich Alain; Sterner Olov; Fontana Gabriele; Bombardelli Ezio; Pera Paula; Bernacki Ralph J
Structure-activity relationships of ring C-secotaxoids. 1. Acylative modifications.
Journal of natural products 2004;67(2):184-8.
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2003: Baldelli Eleonora; Battaglia Arturo; Bombardelli Ezio; Carenzi Giacomo; Fontana Gabriele; Gambini Andrea; Gelmi Maria Luisa; Guerrini Andrea; Pocar Donato
Diastereoselective 14beta-hydroxylation of baccatin III derivatives.
The Journal of organic chemistry 2003;68(25):9773-9.
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2003: Battaglia Arturo; Bernacki Ralph J; Bertucci Carlo; Bombardelli Ezio; Cimitan Samanta; Ferlini Cristiano; Fontana Gabriele; Guerrini Andrea; Riva Antonella
Synthesis and biological evaluation of 2'-methyl taxoids derived from baccatin III and 14beta-OH-baccatin III 1,14-carbonate.
Journal of medicinal chemistry 2003;46(23):4822-5.
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2003: Gallo D; Giacomelli S; Ferlini C; Raspaglio G; Apollonio P; Prislei S; Riva A; Morazzoni P; Bombardelli E; Scambia G
Antitumour activity of the silybin-phosphatidylcholine complex, IdB 1016, against human ovarian cancer.
European journal of cancer (Oxford, England : 1990) 2003;39(16):2403-10.
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2003: Serra Salvatore; Vacca Giovanni; Tumatis Silvia; Carrucciu Angela; Morazzoni Paolo; Bombardelli Ezio; Colombo Giancarlo; Gessa Gian Luigi; Carai Mauro A M
Anti-relapse properties of IDN 5082, a standardized extract of Salvia miltiorrhiza, in alcohol-preferring rats.
Journal of ethnopharmacology 2003;88(2-3):249-52.
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2003: Mauri Pierluigi; Minoggio Markus; Iemoli Loredana; Rossoni Giuseppe; Morazzoni Paolo; Bombardelli Ezio; Pietta Piergiorgio
Liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry of terpene lactones in plasma of animals.
Journal of pharmaceutical and biomedical analysis 2003;32(4-5):633-9.
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2003: Vacca Giovanni; Colombo Giancarlo; Brunetti Giuliana; Melis Samuele; Molinari Daniela; Serra Salvatore; Seghizzi Roberto; Morazzoni Paolo; Bombardelli Ezio; Gessa Gian Luigi; Carai Mauro A M
Reducing effect of Salvia miltiorrhiza extracts on alcohol intake: influence of vehicle.
Phytotherapy research : PTR 2003;17(5):537-41.
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2003: Battaglia Arturo; Bertucci Carlo; Bombardelli Ezio; Cimitan Samanta; Guerrini Andrea; Morazzoni Paolo; Riva Antonella
Synthesis and HSA binding characterisation of the water soluble 7-succinylpaclitaxel.
European journal of medicinal chemistry 2003;38(4):383-9.
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2003: Ferlini Cristiano; Ojima Iwao; Distefano Mariagrazia; Gallo Daniela; Riva Antonella; Morazzoni Paolo; Bombardelli Ezio; Mancuso Salvatore; Scambia Giovanni
Second generation taxanes: from the natural framework to the challenge of drug resistance.
Current medicinal chemistry. Anti-cancer agents 2003;3(2):133-8.
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2003: Pratesi G; Laccabue D; Lanzi C; Cassinelli G; Supino R; Zucchetti M; Frapolli R; D'Incalci M; Bombardelli E; Morazzoni P; Riva A; Zunino F
IDN 5390: an oral taxane candidate for protracted treatment schedules.
British journal of cancer 2003;88(6):965-72.
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2003: Brunetti Giuliana; Serra Salvatore; Vacca Giovanni; Lobina Carla; Morazzoni Paolo; Bombardelli Ezio; Colombo Giancarlo; Gessa Gian Luigi; Carai Mauro A M
IDN 5082, a standardized extract of Salvia miltiorrhiza, delays acquisition of alcohol drinking behavior in rats.
Journal of ethnopharmacology 2003;85(1):93-7.
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2002: Gallo Daniela; Ferrandina Gabriella; Giacomelli Sabrina; Fruscella Erika; Zannoni GianFranco; Morazzoni Paolo; Riva Antonella; Bombardelli Ezio; Mancuso Salvatore; Scambia Giovanni
Dietary soy modulation of biochemical parameters in DMBA-induced mammary tumors.
Cancer letters 2002;186(1):43-8.
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2002: Ferri Paola; Bruno Cesare; Cecchini Tiziana; Ciaroni Sandra; Ambrogini Patrizia; Guidi Loretta; Cuppini Riccardo; Bombardelli Ezio; Morazzoni Paolo; Riva Antonella; Del Grande Paolo
Effects of thiocolchicine on axonal cytoskeleton of the rat peroneus nerve.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2002;54(3):211-6.
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2002: Zaffaroni M; Frapolli R; Colombo T; Fruscio R; Bombardelli E; Morazzoni P; Riva A; D'Incalci M; Zucchetti M
High-performance liquid chromatographic assay for the determination of the novel C-Seco-taxane derivative (IDN 5390) in mouse plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;780(1):93-8.
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2002: Cassinelli Giuliana; Lanzi Cinzia; Supino Rosanna; Pratesi Graziella; Zuco Valentina; Laccabue Diletta; Cuccuru Giuditta; Bombardelli Ezio; Zunino Franco
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2647-54.
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2002: Verotta Luisella; Appendino Giovanni; Belloro Emanuela; Bianchi Federica; Sterner Olov; Lovati Marco; Bombardelli Ezio
Synthesis and biological evaluation of hyperforin analogues. Part I. Modification of the enolized cyclohexanedione moiety.
Journal of natural products 2002;65(4):433-8.
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2002: Taraboletti Giulia; Micheletti Gianluca; Rieppi Monica; Poli Maura; Turatto Michele; Rossi Cosmo; Borsotti Patrizia; Roccabianca Paola; Scanziani Eugenio; Nicoletti Maria Ines; Bombardelli Ezio; Morazzoni Paolo; Riva Antonella; Giavazzi Raffaella
Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1182-8.
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2002: Giacomelli Sabrina; Gallo Daniela; Apollonio Patrizia; Ferlini Cristiano; Distefano Mariagrazia; Morazzoni Paolo; Riva Antonella; Bombardelli Ezio; Mancuso Salvatore; Scambia Giovanni
Silybin and its bioavailable phospholipid complex (IdB 1016) potentiate in vitro and in vivo the activity of cisplatin.
Life sciences 2002;70(12):1447-59.
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2001: Laccabue D; Tortoreto M; Veneroni S; Perego P; Scanziani E; Zucchetti M; Zaffaroni M; D'Incalci M; Bombardelli E; Zunino F; Pratesi G
A novel taxane active against an orthotopically growing human glioma xenograft.
Cancer 2001;92(12):3085-92.
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2001: Gallo D; Giacomelli S; Cantelmo F; Zannoni G F; Ferrandina G; Fruscella E; Riva A; Morazzoni P; Bombardelli E; Mancuso S; Scambia G
Chemoprevention of DMBA-induced mammary cancer in rats by dietary soy.
Breast cancer research and treatment 2001;69(2):153-64.
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2001: Barboni L; Lambertucci C; Appendino G; Vander Velde D G; Himes R H; Bombardelli E; Wang M; Snyder J P
Synthesis and NMR-driven conformational analysis of taxol analogues conformationally constrained on the C13 side chain.
Journal of medicinal chemistry 2001;44(10):1576-87.
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2001: Mauri P; Simonetti P; Gardana C; Minoggio M; Morazzoni P; Bombardelli E; Pietta P
Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts.
Rapid communications in mass spectrometry : RCM 2001;15(12):929-34.
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2000: Ferlini C; Distefano M; Pignatelli F; Lin S; Riva A; Bombardelli E; Mancuso S; Ojima I; Scambia G
Antitumour activity of novel taxanes that act at the same time as cytotoxic agents and P-glycoprotein inhibitors.
British journal of cancer 2000;83(12):1762-8.
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2000: Carai M A; Agabio R; Bombardelli E; Bourov I; Gessa G L; Lobina C; Morazzoni P; Pani M; Reali R; Vacca G; Colombo G
Potential use of medicinal plants in the treatment of alcoholism.
Fitoterapia 2000;71 Suppl 1():S38-42.
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2000: Polizzi D; Pratesi G; Monestiroli S; Tortoreto M; Zunino F; Bombardelli E; Riva A; Morazzoni P; Colombo T; D'Incalci M; Zucchetti M
Oral efficacy and bioavailability of a novel taxane.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):2070-4.
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2000: Verotta L; Appendino G; Jakupovic J; Bombardelli E
Hyperforin analogues from St. John's wort (Hypericum perforatum).
Journal of natural products 2000;63(3):412-5.
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2000: Nicoletti M I; Colombo T; Rossi C; Monardo C; Stura S; Zucchetti M; Riva A; Morazzoni P; Donati M B; Bombardelli E; D'Incalci M; Giavazzi R
IDN5109, a taxane with oral bioavailability and potent antitumor activity.
Cancer research 2000;60(4):842-6.
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2000: De Vincenzo R; Ferlini C; Distefano M; Gaggini C; Riva A; Bombardelli E; Morazzoni P; Valenti P; Belluti F; Ranelletti F O; Mancuso S; Scambia G
In vitro evaluation of newly developed chalcone analogues in human cancer cells.
Cancer chemotherapy and pharmacology 2000;46(4):305-12.
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2000: Gallo D; Ferlini C; Distefano M; Cantelmo F; Gaggini C; Fattorossi A; Riva A; Bombardelli E; Proietti E; Mancuso S; Scambia G
Anti-tumour activity of a panel of taxanes toward a cellular model of human cervical cancer.
Cancer chemotherapy and pharmacology 2000;45(2):127-32.
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1999: Colombo T; Frapolli R; Bombardelli E; Morazzoni P; Riva A; D'Incalci M; Zucchetti M
High-performance liquid chromatographic assay for the determination of the novel taxane derivative IDN5109 in mouse plasma.
Journal of chromatography. B, Biomedical sciences and applications 1999;736(1-2):135-41.
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1999: Gelmi M L; Mottadelli S; Pocar D; Riva A; Bombardelli E; De Vincenzo R; Scambia G
N-deacetyl-N-aminoacylthiocolchicine derivatives: synthesis and biological evaluation on MDR-positive and MDR-negative human cancer cell lines.
Journal of medicinal chemistry 1999;42(25):5272-6.
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1999: Gallo D; Cantelmo F; Distefano M; Ferlini C; Zannoni G F; Riva A; Morazzoni P; Bombardelli E; Mancuso S; Scambia G
Reproductive effects of dietary soy in female Wistar rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1999;37(5):493-502.
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1999: Colombo G; Agabio R; Lobina C; Reali R; Morazzoni P; Bombardelli E; Gessa G L
Salvia miltiorrhiza extract inhibits alcohol absorption, preference, and discrimination in sP rats.
Alcohol (Fayetteville, N.Y.) 1999;18(1):65-70.
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1999: Polizzi D; Pratesi G; Tortoreto M; Supino R; Riva A; Bombardelli E; Zunino F
A novel taxane with improved tolerability and therapeutic activity in a panel of human tumor xenografts.
Cancer research 1999;59(5):1036-40.
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1999: Ferlini C; Distefano M; Pierelli L; Bonanno G; Riva A; Bombardelli E; Ojima I; Mancuso S; Scambia G
Cytotoxic effects toward human hematopoietic progenitor cells and tumor cell lines of paclitaxel, docetaxel, and newly developed analogues IDN5109, IDN5111, and IDN5127.
Oncology research 1999;11(10):471-8.
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1999: De Vincenzo R; Ferlini C; Distefano M; Gaggini C; Riva A; Bombardelli E; Morazzoni P; Danieli B; Capelli G; Mancuso S; Scambia G
Biological evaluation on different human cancer cell lines of novel colchicine analogs.
Oncology research 1999;11(3):145-52.
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1998: Pietta P; Simonetti P; Gardana C; Brusamolino A; Morazzoni P; Bombardelli E
Relationship between rate and extent of catechin absorption and plasma antioxidant status.
Biochemistry and molecular biology international 1998;46(5):895-903.
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1998: Carini M; Maffei Facino R; Aldini G; Callonii M T; Bombardelli E; Morazzoni P
The protection of polyunsaturated fatty acids in micellar systems against UVB-induced photo-oxidation by procyanidins from Vitis vinifera L., and the protective synergy with vitamin E.
International journal of cosmetic science 1998;20(4):203-15.
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1998: Distefano M; Scambia G; Ferlini C; Gallo D; De Vincenzo R; Filippini P; Riva A; Bombardelli E; Mancuso S
Antitumor activity of paclitaxel (taxol) analogues on MDR-positive human cancer cells.
Anti-cancer drug design 1998;13(5):489-99.
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1998: De Vincenzo R; Scambia G; Ferlini C; Distefano M; Filippini P; Riva A; Bombardelli E; Pocar D; Gelmi M L; Benedetti Panici P; Mancuso S
Antiproliferative activity of colchicine analogues on MDR-positive and MDR-negative human cancer cell lines.
Anti-cancer drug design 1998;13(1):19-33.
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1998: Pietta P G; Simonetti P; Gardana C; Brusamolino A; Morazzoni P; Bombardelli E
Catechin metabolites after intake of green tea infusions.
BioFactors (Oxford, England) 1998;8(1-2):111-8.
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1997: Distefano M; Scambia G; Ferlini C; Gaggini C; De Vincenzo R; Riva A; Bombardelli E; Ojima I; Fattorossi A; Panici P B; Mancuso S
Anti-proliferative activity of a new class of taxanes (14beta-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells.
International journal of cancer. Journal international du cancer 1997;72(5):844-50.
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1997: Ferlini C; Scambia G; Distefano M; Filippini P; Isola G; Riva A; Bombardelli E; Fattorossi A; Benedetti Panici P; Mancuso S
Synergistic antiproliferative activity of tamoxifen and docetaxel on three oestrogen receptor-negative cancer cell lines is mediated by the induction of apoptosis.
British journal of cancer 1997;75(6):884-91.
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