FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

John Subjeck

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Phenomena

Hot Temperature

Disorders

Neoplasms

Physiology

Procedures

Immunotherapy

Co-author Network

Publications

TOP 3
Xiaofei Yu; Huanfa Yi; Paul B Fisher; Chunqing Guo; Jie Qian; John R Subjeck; Xiang-Yang Wang
A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity.
Daming Zuo; Huanfa Yi; Xiaofei Yu; Huiping Zhou; Zhengliang Chen; Chunqing Guo; Xiao Lu; Zhi-Ping Lv; Jie Qian; Arun J Sanyal; John R Subjeck; Hongxia Wang; Xiang-Yang Wang
Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury.
Chunqing Guo; Ross B Mikkelsen; Jie Qian; John R Subjeck; Xiaolei Sun; Gary Yang; Huanfa Yi; Xiaofei Yu; Daming Zuo; Paul B Fisher; Barbara A Foster; Xiang-Yang Wang
In situ vaccination with CD204 gene-silenced dendritic cell, not unmodified dendritic cell, enhances radiation therapy of prostate cancer.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of John Subjeck (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Xiaofei Yu; Huanfa Yi; Paul B Fisher; Chunqing Guo; Jie Qian; John R Subjeck; Xiang-Yang Wang
A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity.
Cancer research 2013;73(7):2093-103.
2013: Daming Zuo; Huanfa Yi; Xiaofei Yu; Huiping Zhou; Zhengliang Chen; Chunqing Guo; Xiao Lu; Zhi-Ping Lv; Jie Qian; Arun J Sanyal; John R Subjeck; Hongxia Wang; Xiang-Yang Wang
Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury.
Hepatology (Baltimore, Md.) 2013;57(1):228-38.
2012: Chunqing Guo; Ross B Mikkelsen; Jie Qian; John R Subjeck; Xiaolei Sun; Gary Yang; Huanfa Yi; Xiaofei Yu; Daming Zuo; Paul B Fisher; Barbara A Foster; Xiang-Yang Wang
In situ vaccination with CD204 gene-silenced dendritic cell, not unmodified dendritic cell, enhances radiation therapy of prostate cancer.
Molecular cancer therapeutics 2012;11(11):2331-41.
2012: Daming Zuo; Huanfa Yi; Xiaofei Yu; Xing Chen; Zhengliang Chen; Daniel H Conrad; Paul B Fisher; Chunqing Guo; Tai L Guo; John R Subjeck; Xiang-Yang Wang
Molecular chaperoning by glucose-regulated protein 170 in the extracellular milieu promotes macrophage-mediated pathogen sensing and innate immunity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(4):1493-505.
2012: Huanfa Yi; Xiaofei Yu; Daming Zuo; Zhengliang Chen; Fanlei Hu; Masoud H Manjili; John R Subjeck; Xiang-Yang Wang
Suppression of antigen-specific CD4+ T cell activation by SRA/CD204 through reducing the immunostimulatory capability of antigen-presenting cell.
Journal of molecular medicine (Berlin, Germany) 2012;90(4):413-26.
2011: Huanfa Yi; Xiaofei Yu; Daming Zuo; Paul B Fisher; Ping Gao; Chunqing Guo; Masoud H Manjili; Jie Qian; John R Subjeck; Xiang-Yang Wang
Targeting the immunoregulator SRA/CD204 potentiates specific dendritic cell vaccine-induced T-cell response and antitumor immunity.
Cancer research 2011;71(21):6611-20.
2011: Jie Qian; Elizabeth A Repasky; John R Subjeck; Xing Chen; Chunqing Guo; John M Kane; Huanfa Yi; Xiaofei Yu; Daming Zuo; Xiang-Yang Wang
CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(6):2905-14.
2011: John R Subjeck; Elizabeth A Repasky
Heat shock proteins and cancer therapy: the trail grows hotter!
Oncotarget 2011;2(6):433-4.
2011: Xiaofei Yu; Huanfa Yi; Chunqing Guo; Daming Zuo; Yanping Wang; Hyung L Kim; John R Subjeck; Xiang-Yang Wang
Pattern recognition scavenger receptor CD204 attenuates Toll-like receptor 4-induced NF-kappaB activation by directly inhibiting ubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.
The Journal of biological chemistry 2011;286(21):18795-806.
2011: Fanlei Hu; Xiaofei Yu; Hongxia Wang; Daming Zuo; Chunqing Guo; Huanfa Yi; Boaz Tirosh; John R Subjeck; Xiaoyan Qiu; Xiang-Yang Wang
ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells.
European journal of immunology 2011;41(4):1086-97.
2011: Xiang-Yang Wang; Huanfa Yi; Xiaofei Yu; Damin Zuo; John R Subjeck
Enhancing antigen cross-presentation and T-cell priming by complexing protein antigen to recombinant large heat-shock protein.
Methods in molecular biology (Clifton, N.J.) 2011;787():277-87.
2010: Yanping Wang; Xiang-Yang Wang; John R Subjeck; Hyung L Kim
Covalent crosslinking of tumor antigens stimulates an antitumor immune response.
Vaccine 2010;28(40):6613-20.
2010: Xiang-Yang Wang; Xiaolei Sun; Xing Chen; John G Facciponte; Elizabeth A Repasky; John Kane; John R Subjeck
Superior antitumor response induced by large stress protein chaperoned protein antigen compared with peptide antigen.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(11):6309-19.
2010: Hilal Arnouk; Evan R Zynda; Xiang-Yang Wang; Bonnie L Hylander; Masoud H Manjili; Elizabeth A Repasky; John R Subjeck; A Latif Kazim
Tumour secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumour immune response in vivo.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2010;26(4):366-75.
2009: Ping Gao; Xiaolei Sun; Xing Chen; John R Subjeck; Xiang-Yang Wang
Secretion of stress protein grp170 promotes immune-mediated inhibition of murine prostate tumor.
Cancer immunology, immunotherapy : CII 2009;58(8):1319-28.
2009: Huanfa Yi; Xiaofei Yu; Ping Gao; Yanping Wang; Sun-Hee Baek; Xing Chen; Hyung L Kim; John R Subjeck; Xiang-Yang Wang
Pattern recognition scavenger receptor SRA/CD204 down-regulates Toll-like receptor 4 signaling-dependent CD8 T-cell activation.
Blood 2009;113(23):5819-28.
2007: S H Beachy; A J Kisailus; Elizabeth A Repasky; John R Subjeck; Xiang-Yang Wang; A Latif Kazim
Engineering secretable forms of chaperones for immune modulation and vaccine development.
Methods (San Diego, Calif.) 2007;43(3):184-93.
2007: John G Facciponte; Xiang-Yang Wang; John R Subjeck
Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I.
European journal of immunology 2007;37(8):2268-79.
2007: Hyung L Kim; Xiaolei Sun; John R Subjeck; Xiang-Yang Wang
Evaluation of renal cell carcinoma vaccines targeting carbonic anhydrase IX using heat shock protein 110.
Cancer immunology, immunotherapy : CII 2007;56(7):1097-105.
2007: Xiang-Yang Wang; John G Facciponte; Xing Chen; John R Subjeck; Elizabeth A Repasky
Scavenger receptor-A negatively regulates antitumor immunity.
Cancer research 2007;67(10):4996-5002.
2006: Xiang-Yang Wang; Hilal Arnouk; Xing Chen; Latif Kazim; Elizabeth A Repasky; John R Subjeck
Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1543-51.
2006: Ying Li; John R Subjeck; Gary Yang; Elizabeth A Repasky; Xiang-Yang Wang
Generation of anti-tumor immunity using mammalian heat shock protein 70 DNA vaccines for cancer immunotherapy.
Vaccine 2006;24(25):5360-70.
2006: Brahm H Segal; Xiang-Yang Wang; Carly G Dennis; Richard Youn; Elizabeth A Repasky; Masoud H Manjili; John R Subjeck
Heat shock proteins as vaccine adjuvants in infections and cancer.
Drug discovery today 2006;11(11-12):534-40.
2006: Masoud H Manjili; Jun-Eui Park; John G Facciponte; Xiang-Yang Wang; John R Subjeck
Immunoadjuvant chaperone, GRP170, induces 'danger signals' upon interaction with dendritic cells.
Immunology and cell biology 2006;84(2):203-8.
2006: Masoud H Manjili; Hilal Arnouk; Keith L Knutson; Maciej Kmieciak; Mary L Disis; John R Subjeck; A Latif Kazim
Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce "danger signals".
Breast cancer research and treatment 2006;96(3):233-41.
2006: John G Facciponte; Xiang-Yang Wang; Ian J MacDonald; Jun-Eui Park; Hilal Arnouk; Melissa J Grimm; Ying Li; Hyung Kim; Masoud H Manjili; Douglas P Easton; John R Subjeck
Heat shock proteins HSP70 and GP96: structural insights.
Cancer immunology, immunotherapy : CII 2006;55(3):339-46.
2006: Jun-Eui Park; John G Facciponte; Xing Chen; Ian MacDonald; Elizabeth A Repasky; Masoud H Manjili; Xiang-Yang Wang; John R Subjeck
Chaperoning function of stress protein grp170, a member of the hsp70 superfamily, is responsible for its immunoadjuvant activity.
Cancer research 2006;66(2):1161-8.
2006: Xiang-Yang Wang; John G Facciponte; John R Subjeck
Molecular chaperones and cancer immunotherapy.
Handbook of experimental pharmacology 2006;(172):305-29.
2005: Xiang-Yang Wang; Ying Li; G Yang; John R Subjeck
Current ideas about applications of heat shock proteins in vaccine design and immunotherapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(8):717-22.
2005: Masoud H Manjili; Juneui Park; John G Facciponte; John R Subjeck
HSP110 induces "danger signals" upon interaction with antigen presenting cells and mouse mammary carcinoma.
Immunobiology 2005;210(5):295-303.
2005: John G Facciponte; Ian J MacDonald; Xiang-Yang Wang; Hyung Kim; Masoud H Manjili; John R Subjeck
Heat shock proteins and scavenger receptors: role in adaptive immune responses.
Immunological investigations 2005;34(3):325-42.
2004: Masoud H Manjili; Xiang-Yang Wang; Ian J MacDonald; Hilal Arnouk; Gary Y Yang; Michele T Pritchard; John R Subjeck
Cancer immunotherapy and heat-shock proteins: promises and challenges.
Expert opinion on biological therapy 2004;4(3):363-73.
2004: Kazuhisa Gotoh; Kohsuke Nonoguchi; Hiroaki Higashitsuji; Yoshiyuki Kaneko; Toshiharu Sakurai; Yasuhiko Sumitomo; Katsuhiko Itoh; John R Subjeck; Jun Fujita
Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas.
FEBS letters 2004;560(1-3):19-24.
2004: Xiang-Yang Wang; Masoud H Manjili; Juneui Park; Xing Chen; Elizabeth A Repasky; John R Subjeck
Development of cancer vaccines using autologous and recombinant high molecular weight stress proteins.
Methods (San Diego, Calif.) 2004;32(1):13-20.
2003: Juneui Park; Douglas P Easton; Xing Chen; Ian J MacDonald; Xiang-Yang Wang; John R Subjeck
The chaperoning properties of mouse grp170, a member of the third family of hsp70 related proteins.
Biochemistry 2003;42(50):14893-902.
2003: Masoud H Manjili; Xiang-Yang Wang; Xing Chen; Thomas Martin; Elizabeth A Repasky; Robert Henderson; John R Subjeck
HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4054-61.
2003: Sean P Colgan; Richard S Pitman; Takashi Nagaishi; Atsushi Mizoguchi; Emiko Mizoguchi; Lloyd F Mayer; Ling Shao; Ryan Sartor; John R Subjeck; Richard S Blumberg
Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells.
The Journal of clinical investigation 2003;112(5):745-54.
2003: Xiang-Yang Wang; Latif Kazim; Elizabeth A Repasky; John R Subjeck
Immunization with tumor-derived ER chaperone grp170 elicits tumor-specific CD8+ T-cell responses and reduces pulmonary metastatic disease.
International journal of cancer. Journal international du cancer 2003;105(2):226-31.
2003: Xiang-Yang Wang; Xing Chen; Masoud H Manjili; Elizabeth A Repasky; Robert Henderson; John R Subjeck
Targeted immunotherapy using reconstituted chaperone complexes of heat shock protein 110 and melanoma-associated antigen gp100.
Cancer research 2003;63(10):2553-60.
2002: Masoud H Manjili; Xiang-Yang Wang; Juneui Park; Ian J MacDonald; Ying Li; R C A A Van Schie; John R Subjeck
Cancer immunotherapy: stress proteins and hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002;18(6):506-20.
2002: Xiang-Yang Wang; Ying Li; Masoud H Manjili; Elizabeth A Repasky; Drew M Pardoll; John R Subjeck
Hsp110 over-expression increases the immunogenicity of the murine CT26 colon tumor.
Cancer immunology, immunotherapy : CII 2002;51(6):311-9.
2002: Masoud H Manjili; Robert Henderson; Xiang-Yang Wang; Xing Chen; Ying Li; Elizabeth A Repasky; Latif Kazim; John R Subjeck
Development of a recombinant HSP110-HER-2/neu vaccine using the chaperoning properties of HSP110.
Cancer research 2002;62(6):1737-42.
2002: Masoud H Manjili; Xiang-Yang Wang; Juneui Park; John G Facciponte; Elizabeth A Repasky; John R Subjeck
Immunotherapy of cancer using heat shock proteins.
Frontiers in bioscience : a journal and virtual library 2002;7():d43-52.
2001: Xiang-Yang Wang; Latif Kazim; Elizabeth A Repasky; John R Subjeck
Characterization of heat shock protein 110 and glucose-regulated protein 170 as cancer vaccines and the effect of fever-range hyperthermia on vaccine activity.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):490-7.
2000: Douglas P Easton; Y Kaneko; John R Subjeck
The hsp110 and Grp1 70 stress proteins: newly recognized relatives of the Hsp70s.
Cell stress & chaperones 2000;5(4):276-90.
2000: Xiang-Yang Wang; Y Kaneko; Elizabeth A Repasky; John R Subjeck
Heat shock proteins and cancer immunotherapy.
Immunological investigations 2000;29(2):131-7.
2000: Xiang-Yang Wang; Xing Chen; H J Oh; Elizabeth A Repasky; Latif Kazim; John R Subjeck
Characterization of native interaction of hsp110 with hsp25 and hsc70.
FEBS letters 2000;465(2-3):98-102.
1999: H J Oh; D Easton; M Murawski; Y Kaneko; John R Subjeck
The chaperoning activity of hsp110. Identification of functional domains by use of targeted deletions.
The Journal of biological chemistry 1999;274(22):15712-8.
1998: Randy Burd; T S Dziedzic; Y Xu; M A Caligiuri; John R Subjeck; Elizabeth A Repasky
Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia.
Journal of cellular physiology 1998;177(1):137-47.
1998: Wan-Chao Wang; L M Goldman; David M Schleider; Michelle M Appenheimer; John R Subjeck; Elizabeth A Repasky; Sharon S Evans
Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):961-9.
1997: H J Oh; Xing Chen; John R Subjeck
Hsp110 protects heat-denatured proteins and confers cellular thermoresistance.
The Journal of biological chemistry 1997;272(50):31636-40.
1997: Y P Di; Elizabeth A Repasky; John R Subjeck
Distribution of HSP70, protein kinase C, and spectrin is altered in lymphocytes during a fever-like hyperthermia exposure.
Journal of cellular physiology 1997;172(1):44-54.
1996: X Chen; D Easton; H J Oh; D S Lee-Yoon; X Liu; John R Subjeck
The 170 kDa glucose regulated stress protein is a large HSP70-, HSP110-like protein of the endoplasmic reticulum.
FEBS letters 1996;380(1-2):68-72.
1995: Y P Di; Elizabeth A Repasky; Andrei Laszlo; S Calderwood; John R Subjeck
Hsp70 translocates into a cytoplasmic aggregate during lymphocyte activation.
Journal of cellular physiology 1995;165(2):228-38.
1995: D Lee-Yoon; D Easton; M Murawski; Randy Burd; John R Subjeck
Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein.
The Journal of biological chemistry 1995;270(26):15725-33.
1993: H Y Lin; P Masso-Welch; Y P Di; J W Cai; J W Shen; John R Subjeck
The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin.
Molecular biology of the cell 1993;4(11):1109-19.
1993: J W Cai; Barbara W Henderson; J W Shen; John R Subjeck
Induction of glucose regulated proteins during growth of a murine tumor.
Journal of cellular physiology 1993;154(2):229-37.
1991: J W Cai; C S Hughes; J W Shen; John R Subjeck
Induction of heat-shock proteins by glutamine. The 'feeding effect'.
FEBS letters 1991;288(1-2):229-32.
1991: Adrian R Black; John R Subjeck
The biology and physiology of the heat shock and glucose-regulated stress protein systems.
Methods and achievements in experimental pathology 1991;15():126-66.
1989: C S Hughes; J W Shen; John R Subjeck
Resistance to etoposide induced by three glucose-regulated stresses in Chinese hamster ovary cells.
Cancer research 1989;49(16):4452-4.
1989: J W Shen; John R Subjeck; Richard B Lock; W E Ross
Depletion of topoisomerase II in isolated nuclei during a glucose-regulated stress response.
Molecular and cellular biology 1989;9(8):3284-91.
1989: Mary taub; J A Syracuse; J W Cai; P Fiorella; John R Subjeck
Glucose deprivation results in the induction of glucose-regulated proteins and domes in MDCK monolayers in hormonally defined serum-free medium.
Experimental cell research 1989;182(1):105-13.
1989: Adrian R Black; John R Subjeck
Involvement of rRNA synthesis in the enhanced survival and recovery of protein synthesis seen in thermotolerance.
Journal of cellular physiology 1989;138(3):439-49.
1987: C S Hughes; Elizabeth A Repasky; Richard B Bankert; R J Johnson; John R Subjeck
Effects of hyperthermia on spectrin expression patterns of murine lymphocytes.
Radiation research 1987;112(1):116-23.
1986: T T Shyy; John R Subjeck; R Heinaman; G Anderson
Effect of growth state and heat shock on nucleolar localization of the 110,000-Da heat shock protein in mouse embryo fibroblasts.
Cancer research 1986;46(9):4738-45.
1986: John R Subjeck; T T Shyy
Stress protein systems of mammalian cells.
The American journal of physiology 1986;250(1 Pt 1):C1-17.
1985: John R Subjeck; J J Sciandra; T T Shyy
Analysis of the expression of the two major proteins of the 70 kilodalton mammalian heat shock family.
International journal of radiation biology and related studies in physics, chemistry, and medicine 1985;47(3):275-84.
1984: J J Sciandra; John R Subjeck
Heat shock proteins and protection of proliferation and translation in mammalian cells.
Cancer research 1984;44(11):5188-94.
1984: J J Sciandra; John R Subjeck; C S Hughes
Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(15):4843-7.
1984: C F Chao; L Ting; John R Subjeck; R J Johnson
The effect of nitroimidazoles on the oxygen consumption rate and respiratory control ratio of beef heart mitochondria.
International journal of radiation oncology, biology, physics 1984;10(8):1391-4.
1984: C F Chao; John R Subjeck; H Brody; J Shen; R J Johnson
The effect of nitroimidazoles on glucose utilization and lactate accumulation in mouse brain.
Radiation research 1984;97(1):87-96.
1983: J J Sciandra; John R Subjeck
The effects of glucose on protein synthesis and thermosensitivity in Chinese hamster ovary cells.
The Journal of biological chemistry 1983;258(20):12091-3.
1983: C F Chao; John R Subjeck; R J Johnson
Behavioural and ultrastructural studies of desmethylmisonidazole-induced neurotoxicity in mice.
The British journal of radiology 1983;56(661):27-31.
1982: John R Subjeck; J J Sciandra; R J Johnson
Heat shock proteins and thermotolerance; a comparison of induction kinetics.
The British journal of radiology 1982;55(656):579-84.
1982: C F Chao; John R Subjeck; R J Johnson
Nitroimidazole inhibition of lactate production in CHO cells.
International journal of radiation oncology, biology, physics 1982;8(3-4):729-32.
1982: J J Sciandra; Elizabeth A Repasky; John R Subjeck; R J Johnson
The effect of high intensity microwave exposure on enucleation of murine erythroid cells in vitro.
The British journal of cancer. Supplement 1982;5():209-14.
1982: John R Subjeck; J J Sciandra; C F Chao; R J Johnson
Heat shock proteins and biological response to hyperthermia.
The British journal of cancer. Supplement 1982;5():127-31.