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Constantin Bona

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Rashpal K Bhogal; Constantin A Bona
Regulatory effect of extracellular signal-regulated kinases (ERK) on type I collagen synthesis in human dermal fibroblasts stimulated by IL-4 and IL-13.
Teodor-D Brumeanu; Anca Preda-Pais; Cristina Stoica; Constantin A Bona; Sofia Casares
Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells.
Adrian Bot; Dan Smith; Bill Phillips; Simona Bot; Constantin A Bona; Habib Zaghouani
Immunologic control of tumors by in vivo Fc gamma receptor-targeted antigen loading in conjunction with double-stranded RNA-mediated immune modulation.

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All Publications

2008: Rashpal K Bhogal; Constantin A Bona
Regulatory effect of extracellular signal-regulated kinases (ERK) on type I collagen synthesis in human dermal fibroblasts stimulated by IL-4 and IL-13.
International reviews of immunology 2008;27(6):472-96.
2007: Teodor-D Brumeanu; Anca Preda-Pais; Cristina Stoica; Constantin A Bona; Sofia Casares
Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells.
Molecular immunology 2007;44(4):530-40.
2006: Adrian Bot; Dan Smith; Bill Phillips; Simona Bot; Constantin A Bona; Habib Zaghouani
Immunologic control of tumors by in vivo Fc gamma receptor-targeted antigen loading in conjunction with double-stranded RNA-mediated immune modulation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1363-74.
2005: Rashpal K Bhogal; Cristina Stoica; Tracy L McGaha; Constantin A Bona
Molecular aspects of regulation of collagen gene expression in fibrosis.
Journal of clinical immunology 2005;25(6):592-603.
2005: Rashpal K Bhogal; Constantin A Bona
B cells: no longer bystanders in liver fibrosis.
The Journal of clinical investigation 2005;115(11):2962-5.
2005: Xiaodong Zhou; Filemon K Tan; Dianna M Milewicz; Xinjian Guo; Constantin A Bona; Frank C Arnett
Autoantibodies to fibrillin-1 activate normal human fibroblasts in culture through the TGF-beta pathway to recapitulate the "scleroderma phenotype".
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4555-60.
2005: William J Phillips; Dan J Smith; Constantin A Bona; Adrian Bot; Habib Zaghouani
Recombinant immunoglobulin-based epitope delivery: a novel class of autoimmune regulators.
International reviews of immunology 2005;24(5-6):501-17.
2005: Ioana Preda; Robert C McEvoy; Marvin Lin; Constantin A Bona; Robert Rapaport; Teodor-D Brumeanu; Sofia Casares
Soluble, dimeric HLA DR4-peptide chimeras: an approach for detection and immunoregulation of human type-1 diabetes.
European journal of immunology 2005;35(9):2762-75.
2005: Anca Preda-Pais; Alexandru C Stan; Sofia Casares; Constantin A Bona; Teodor-D Brumeanu
Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes.
Journal of autoimmunity 2005;25(1):21-32.
2004: Takao Kodera; Dorel Radu; Tracy L McGaha; Patty Zwolo; Cristina Stoica; Hilde Cheroute; Roberta R Pollock; Constantin A Bona
Cellular and molecular studies of B cells exhibiting reverse somatic mutation throughout life.
Genes to cells : devoted to molecular & cellular mechanisms 2004;9(11):1005-16.
2004: Constantin A Bona; Dorel Radu; Takao Kodera
Molecular studies on the diversification of hemagglutinin-specific human neonatal repertoire subsequent to immunization with naked DNA.
Vaccine 2004;22(13-14):1624-30.
2004: Hong Zhu; Constantin A Bona; Tracy L McGaha
Polymorphisms of the TGF-beta1 promoter in tight skin (TSK) mice.
Autoimmunity 2004;37(1):51-5.
2003: Tracy L McGaha; Maithao N Le; Takao Kodera; Cristina Stoica; Jinfang Zhu; William Paul; Constantin A Bona
Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts.
Arthritis and rheumatism 2003;48(8):2275-84.
2003: Dorel Radu; Takao Kodera; Constantin A Bona
Expression of activation-induced cytidine deaminase decreases throughout the life.
Journal of cellular and molecular medicine 2003;7(2):141-5.
2002: Tracy L McGaha; Takao Kodera; Harry Spiera; Alexandru C Stan; Mark Pines; Constantin A Bona
Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.
Arthritis and rheumatism 2002;46(10):2748-61.
2002: Takao Kodera; Filemon K Tan; Takeshi Sasaki; Frank C Arnett; Constantin A Bona
Association of 5'-untranslated region of the Fibrillin-1 gene with Japanese scleroderma.
Gene 2002;297(1-2):61-7.
2002: Tracy L McGaha; Takao Kodera; Robert Phelps; Harry Spiera; Mark Pines; Constantin A Bona
Effect of halofuginone on the development of tight skin (TSK) syndrome.
Autoimmunity 2002;35(4):277-82.
2002: Tracy L McGaha; Constantin A Bona
Role of profibrogenic cytokines secreted by T cells in fibrotic processes in scleroderma.
Autoimmunity reviews 2002;1(3):174-81.
2002: Adrian Bot; Constantin A Bona
Genetic immunization of neonates.
Microbes and infection / Institut Pasteur 2002;4(4):511-20.
2002: Takao Kodera; Tracy L McGaha; Robert Phelps; William Paul; Constantin A Bona
Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3800-5.
2002: Tracy L McGaha; Robert G Phelps; Harry Spiera; Constantin A Bona
Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.
The Journal of investigative dermatology 2002;118(3):461-70.
2001: Dorel Radu; Marc E Weksler; Constantin A Bona
Maintenance of size and function of influenza virus hemagglutinin specific transgenic T-cell clone during life.
Journal of cellular and molecular medicine 2001;5(4):388-96.
2001: Sofia Casares; Constantin A Bona; Teodor-D Brumeanu
Modulation of CD4 T cell function by soluble MHC II-peptide chimeras.
International reviews of immunology 2001;20(5):547-73.
2001: Dorel Radu; S Antohi; Adrian Bot; A Miller; A Mirarchi; Constantin A Bona
Effect of maternal antibodies on influenza virus-specific immune response elicited by inactivated virus and naked DNA.
Scandinavian journal of immunology 2001;53(5):475-82.
2001: Filemon K Tan; N Wang; M Kuwana; R Chakraborty; Constantin A Bona; Dianna M Milewicz; Frank C Arnett
Association of fibrillin 1 single-nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations.
Arthritis and rheumatism 2001;44(4):893-901.
2001: Sofia Casares; Constantin A Bona; Teodor-D Brumeanu
Enzymatically mediated engineering of multivalent MHC class II-peptide chimeras.
Protein engineering 2001;14(3):195-200.
2001: Adrian Bot; M Shearer; Simona Bot; M Avriette; Adolfo Garcia-Sastre; G White; C Woods; R Kennedy; Constantin A Bona
Induction of immunological memory in baboons primed with DNA vaccine as neonates.
Vaccine 2001;19(15-16):1960-7.
2001: Sofia Casares; Alexandru C Stan; Constantin A Bona; Teodor-D Brumeanu
Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II--peptide chimera.
Nature biotechnology 2001;19(2):142-7.
2001: Teodor-D Brumeanu; Constantin A Bona; Sofia Casares
T-cell tolerance and autoimmune diabetes.
International reviews of immunology 2001;20(2):301-31.
2001: Alexandru C Stan; Sofia Casares; Teodor-D Brumeanu; D M Klinman; Constantin A Bona
CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes.
European journal of immunology 2001;31(1):301-10.
2001: Tracy L McGaha; S Saito; Robert G Phelps; R Gordon; Nancy Noben-Trauth; William Paul; Constantin A Bona
Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.
The Journal of investigative dermatology 2001;116(1):136-43.
2000: Dorel Radu; Nancy Noben-Trauth; Jane Hu-Li; William Paul; Constantin A Bona
A targeted mutation in the IL-4Ralpha gene protects mice against autoimmune diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12700-4.
2000: Filemon K Tan; Frank C Arnett; John D Reveille; Chul Ahn; S Antohi; T Sasaki; K Nishioka; Constantin A Bona
Autoantibodies to fibrillin 1 in systemic sclerosis: ethnic differences in antigen recognition and lack of correlation with specific clinical features or HLA alleles.
Arthritis and rheumatism 2000;43(11):2464-71.
2000: S Saito; H Nishimura; Robert G Phelps; I Wolf; M Suzuki; T Honjo; Constantin A Bona
Induction of skin fibrosis in mice expressing a mutated fibrillin-1 gene.
Molecular medicine (Cambridge, Mass.) 2000;6(10):825-36.
2000: Jane H Morse; S Antohi; KN Kasturi; S Saito; M Fotino; M Humbert; G Simonneau; R J Basst; Constantin A Bona
Fine specificity of anti-fibrillin-1 autoantibodies in primary pulmonary hypertension syndrome.
Scandinavian journal of immunology 2000;51(6):607-11.
2000: Adrian Bot; Alexandru C Stan; K Inaba; R Steinman; Constantin A Bona
Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer.
International immunology 2000;12(6):825-32.
2000: Ingrid Lundberg; S Antohi; K Takeuki; Frank C Arnett; G Steiner; Teodor-D Brumeanu; Lars Klareskog; Constantin A Bona
Kinetics of anti-fibrillin-1 autoantibodies in MCTD and CREST syndrome.
Journal of autoimmunity 2000;14(3):267-74.
1999: Frank C Arnett; Filemon K Tan; Y Uziel; Ronald M Laxer; Bernice R Krafchik; S Antohi; Constantin A Bona
Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin 1, in patients with localized scleroderma.
Arthritis and rheumatism 1999;42(12):2656-9.
1999: S Saito; KN Kasturi; Constantin A Bona
Genetic and immunologic features associated with scleroderma-like syndrome of TSK mice.
Current rheumatology reports 1999;1(1):34-7.
1999: Sofia Casares; Cong S Zong; Dorel Radu; A Miller; Constantin A Bona; Teodor-D Brumeanu
Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation.
The Journal of experimental medicine 1999;190(4):543-53.
1999: Filemon K Tan; Frank C Arnett; S Antohi; S Saito; A Mirarchi; Harry Spiera; T Sasaki; O Shoichi; K Takeuchi; Janardan P Pandey; Richard M Silver; C LeRoy; A E Postlethwaite; Constantin A Bona
Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):1066-72.
1999: S Saito; H Nishimura; Teodor-D Brumeanu; Sofia Casares; Alexandru C Stan; T Honjo; Constantin A Bona
Characterization of mutated protein encoded by partially duplicated fibrillin-1 gene in tight skin (TSK) mice.
Molecular immunology 1999;36(3):169-76.
1999: Alexandru C Stan; Gerhard Franz Walter; K Welte; B Schneider; Constantin A Bona; T Pietsch
Expression of granulocyte colony-stimulating factor in recurrent glial tumors is inversely correlated with tumor progression.
Journal of neuroimmunology 1999;94(1-2):66-73.
1999: Dorel Radu; S Antohi; Adrian Bot; Marc E Weksler; Constantin A Bona
Plasmid expressing the influenza HA gene protects old mice from lethal challenge with influenza virus.
Viral immunology 1999;12(3):217-26.
1999: Dorel Radu; Teodor-D Brumeanu; Robert C McEvoy; Constantin A Bona; Sofia Casares
Escape from self-tolerance leads to neonatal insulin-dependent diabetes mellitus.
Autoimmunity 1999;30(4):199-207.
1999: Adrian Bot; M Shearer; Simona Bot; C Woods; J Limmer; R Kennedy; Sofia Casares; Constantin A Bona
Induction of antibody response by DNA immunization of newborn baboons against influenza virus.
Viral immunology 1999;12(2):91-6.
1999: Alexandru C Stan; Dorel Radu; Sofia Casares; Constantin A Bona; Teodor-D Brumeanu
Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen.
Cancer research 1999;59(1):115-21.
1998: Adrian Bot; Simona Bot; Constantin A Bona
Enhanced protection against influenza virus of mice immunized as newborns with a mixture of plasmids expressing hemagglutinin and nucleoprotein.
Vaccine 1998;16(17):1675-82.
1998: Adrian Bot; Simona Bot; Constantin A Bona
Protective role of gamma interferon during the recall response to influenza virus.
Journal of virology 1998;72(8):6637-45.
1998: S Antohi; Adrian Bot; L Manfield; Constantin A Bona
The reactivity pattern of hemagglutinin-specific clonotypes from mice immunized as neonates or adults with naked DNA.
International immunology 1998;10(5):663-8.
1998: Robert G Phelps; C Murai; S Saito; A Hatakeyama; K Andrikopoulos; KN Kasturi; Constantin A Bona
Effect of targeted mutation in collagen V alpha 2 gene on development of cutaneous hyperplasia in tight skin mice.
Molecular medicine (Cambridge, Mass.) 1998;4(5):356-60.
1998: Adrian Bot; Sofia Casares; Simona Bot; Harald von Boehmer; Constantin A Bona
Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4500-7.
1998: Constantin A Bona; Sofia Casares; Teodor-D Brumeanu
Towards development of T-cell vaccines.
Immunology today 1998;19(3):126-33.
1998: C Murai; S Saito; KN Kasturi; Constantin A Bona
Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice.
Autoimmunity 1998;28(3):151-5.
1998: Adrian Bot; Simona Bot; Adolfo García-Sastre; Constantin A Bona
Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice.
Developmental immunology 1998;5(3):197-210.
1998: Adrian Bot; H Isobe; Constantin A Bona
Immunodeficient mouse models in the characterization of the protective immunity to influenza virus.
Folia microbiologica 1998;43(5):477-8.
1998: Sofia Casares; Adrian Bot; Teodor-D Brumeanu; Constantin A Bona
Foreign peptides expressed in engineered chimeric self molecules.
Biotechnology & genetic engineering reviews 1998;15():159-98.
1997: KN Kasturi; A Hatakeyama; C Murai; R Gordon; Robert G Phelps; Constantin A Bona
B-cell deficiency does not abrogate development of cutaneous hyperplasia in mice inheriting the defective fibrillin-1 gene.
Journal of autoimmunity 1997;10(6):505-17.
1997: Sofia Casares; K Inaba; Teodor-D Brumeanu; Ralph M Steinman; Constantin A Bona
Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope.
The Journal of experimental medicine 1997;186(9):1481-6.
1997: Sofia Casares; Constantin A Bona; Teodor-D Brumeanu
Engineering and characterization of a murine MHC class II-immunoglobulin chimera expressing an immunodominant CD4 T viral epitope.
Protein engineering 1997;10(11):1295-301.
1997: Adrian Bot; S Antohi; Simona Bot; Adolfo Garcia-Sastre; Constantin A Bona
Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene.
International immunology 1997;9(11):1641-50.
1997: Teodor-D Brumeanu; Sofia Casares; P Dehazya; Simona Bot; Constantin A Bona
Presentation of a viral peptide assembled on the carbohydrate moieties of immunoglobulin does not require processing.
European journal of immunology 1997;27(9):2408-16.
1997: Constantin A Bona; C Murai; Sofia Casares; KN Kasturi; H Nishimura; T Honjo; Fumihiko MATSUDA
Structure of the mutant fibrillin-1 gene in the tight skin (TSK) mouse.
DNA research : an international journal for rapid publication of reports on genes and genomes 1997;4(4):267-71.
1997: Teodor-D Brumeanu; Sofia Casares; Adrian Bot; Simona Bot; Constantin A Bona
Immunogenicity of a contiguous T-B synthetic epitope of the A/PR/8/34 influenza virus.
Journal of virology 1997;71(7):5473-80.
1997: Adrian Bot; S Antohi; Constantin A Bona
Immune response of neonates elicited by somatic transgene vaccination with naked DNA.
Frontiers in bioscience : a journal and virtual library 1997;2():d173-88.
1997: KN Kasturi; T Muryoi; S Shibata; A Hatakeyama; C Murai; Y Simakoshi; Constantin A Bona
Functional properties and molecular characteristics of autoantibodies associated with tight skin syndrome.
Annals of the New York Academy of Sciences 1997;815():253-62.
1997: Sofia Casares; Teodor-D Brumeanu; Adrian Bot; Constantin A Bona
Protective immunity elicited by vaccination with DNA encoding for a B cell and a T cell epitope of the A/PR/8/34 influenza virus.
Viral immunology 1997;10(3):129-36.
1997: Constantin A Bona; Adrian Bot; Teodor-D Brumeanu
Immunogenicity of viral epitopes expressed on genetically and enzymatically engineered immunoglobulins.
Chemical immunology 1997;65():179-206.
1996: Adrian Bot; A Nangpal; L Pricop; B Bogen; Azad Kaushik; Constantin A Bona
V lambda-light chain genes reconstitute immune responses to defined carbohydrate antigens or haptens by utilizing different VH genes.
Molecular immunology 1996;33(17-18):1359-68.
1996: Adrian Bot; Simona Bot; S Antohi; K Karjalainen; Constantin A Bona
Kinetics of generation and persistence on membrane class II molecules of a viral peptide expressed on foreign and self proteins.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3436-42.
1996: Constantin A Bona
Internal image concept revisited.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1996;213(1):32-42.
1996: Carmelita G Frondoza; Lynne Jones; Noel R Rose; A Hatakeyama; R Phelps; Constantin A Bona
Silicone does not potentiate development of the scleroderma-like syndrome in tight skin (TSK/+) mice.
Journal of autoimmunity 1996;9(4):473-83.
1996: Adrian Bot; A Reichlin; H Isobe; Simona Bot; J Schulman; W M Yokoyama; Constantin A Bona
Cellular mechanisms involved in protection and recovery from influenza virus infection in immunodeficient mice.
Journal of virology 1996;70(8):5668-72.
1996: Teodor-D Brumeanu; Sofia Casares; P E Harris; P Dehazya; I Wolf; H von Boehmer; Constantin A Bona
Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins.
Nature biotechnology 1996;14(6):722-5.
1996: Teodor-D Brumeanu; Adrian Bot; Constantin A Bona; P Dehazya; I Wolf; H Zaghouani
Engineering of doubly antigenized immunoglobulins expressing T and B viral epitopes.
Immunotechnology : an international journal of immunological engineering 1996;2(2):85-95.
1996: A Hatakeyama; KN Kasturi; I Wolf; Robert G Phelps; Constantin A Bona
Correlation between the concentration of serum anti-topoisomerase I autoantibodies and histological and biochemical alterations in the skin of tight skin mice.
Cellular immunology 1996;167(1):135-40.
1996: Adrian Bot; Simona Bot; Adolfo Garcia-Sastre; Constantin A Bona
DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus.
Viral immunology 1996;9(4):207-10.
1996: T Komori; L Pricop; A Hatakeyama; Constantin A Bona; F W Alt
Repertoires of antigen receptors in Tdt congenitally deficient mice.
International reviews of immunology 1996;13(4):317-25.
1996: Carmelita G Frondoza; Lynne Jones; Noel R Rose; A Hatakeyama; R Phelps; Constantin A Bona
Development of scleroderma-like syndrome in Tsk/+ mice is not enhanced by silicone administration.
Current topics in microbiology and immunology 1996;210():299-306.
1995: A Nangpal; J Knott; V Lipsanen; Constantin A Bona; Azad Kaushik
Contribution of the V lambda light chain to the development of the primary antibody repertoire.
Annals of the New York Academy of Sciences 1995;764():296-300.
1995: L Pricop; A Hatakeyama; H Isobe; Constantin A Bona
Analysis of lambda repertoire in kappa-deficient mice.
Clinical immunology and immunopathology 1995;76(3 Pt 2):S179-87.
1995: Teodor-D Brumeanu; P Dehazya; I Wolf; Constantin A Bona
Enzymatically mediated, glycosidic conjugation of immunoglobulins with viral epitopes.
Journal of immunological methods 1995;183(2):185-97.
1995: Teodor-D Brumeanu; H Zaghouani; Constantin A Bona
Purification of antigenized immunoglobulins derivatized with monomethoxypolyethylene glycol.
Journal of chromatography. A 1995;696(2):219-25.
1995: Teodor-D Brumeanu; H Zaghouani; E Elahi; C Daian; Constantin A Bona
Derivatization with monomethoxypolyethylene glycol of Igs expressing viral epitopes obviates adjuvant requirements.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(7):3088-95.
1995: L Pricop; A Hatakeyama; T Moran; Constantin A Bona
Antibody response against poly (Glu60Ala30Tyr10) terpolymer and bacterial levan in kappa-deficient mice.
European journal of immunology 1995;25(4):1039-43.
1995: KN Kasturi; A Hatakeyama; Harry Spiera; Constantin A Bona
Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes.
The Journal of experimental medicine 1995;181(3):1027-36.
1995: H Zaghouani; S A Anderson; Kirk Sperber; C Daian; R C Kennedy; L Mayer; Constantin A Bona
Induction of antibodies to the human immunodeficiency virus type 1 by immunization of baboons with immunoglobulin molecules carrying the principal neutralizing determinant of the envelope protein.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):631-5.
1995: Y Saitoh; Garnett Kelsoe; Constantin A Bona; Azad Kaushik
Skewed VH and V kappa gene family expression and pairing occurs among B lymphocytes in autoimmune motheaten mice.
Autoimmunity 1995;21(3):185-193.
1995: A Hatakeyama; L Pricop; N Kasturi; Constantin A Bona
Study of self reactive antibodies in kappa-light chain deficient mice.
Autoimmunity 1995;20(2):113-20.
1995: H Isobe; T Moran; S Li; A Young; Stanley G Nathenson; Peter Palese; Constantin A Bona
Presentation by a major histocompatibility complex class I molecule of nucleoprotein peptide expressed in two different genes of an influenza virus transfectant.
The Journal of experimental medicine 1995;181(1):203-13.
1994: L Pricop; Teodor-D Brumeanu; E Elahi; T Moran; B S Wang; M Troustine; D Huszar; F Alt; Constantin A Bona
Antibody response elicited by T-dependent and T-independent antigens in gene targeted kappa-deficient mice.
International immunology 1994;6(12):1839-47.
1994: KN Kasturi; X Y Yio; Constantin A Bona
Molecular characterization of J558 genes encoding tight-skin mouse autoantibodies: identical heavy-chain variable genes code for antibodies with different specificities.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):8067-71.
1994: Constantin A Bona; Teodor-D Brumeanu; H Zaghouani
Immunogenicity of microbial peptides grafted in self immunoglobulin molecules.
Cellular and molecular biology (Noisy-le-Grand, France) 1994;40 Suppl 1():21-30.
1994: KN Kasturi; S Shibata; T Muryoi; Constantin A Bona
Tight-skin mouse an experimental model for scleroderma.
International reviews of immunology 1994;11(3):253-71.
1993: Robert G Phelps; C Daian; S Shibata; Raul Fleischmajer; Constantin A Bona
Induction of skin fibrosis and autoantibodies by infusion of immunocompetent cells from tight skin mice into C57BL/6 Pa/Pa mice.
Journal of autoimmunity 1993;6(6):701-18.
1993: Teodor-D Brumeanu; W J Swiggard; R M Steinman; Constantin A Bona; H Zaghouani
Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus.
The Journal of experimental medicine 1993;178(5):1795-9.
1993: H Zaghouani; Y Kuzu; H Kuzu; Teodor-D Brumeanu; W J Swiggard; R M Steinman; Constantin A Bona
Contrasting efficacy of presentation by major histocompatibility complex class I and class II products when peptides are administered within a common protein carrier, self immunoglobulin.
European journal of immunology 1993;23(11):2746-50.
1993: S Li; V Polonis; H Isobe; H Zaghouani; R Guinea; T Moran; Constantin A Bona; Peter Palese
Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1.
Journal of virology 1993;67(11):6659-66.
1993: Y Kuzu; H Kuzu; H Zaghouani; Constantin A Bona
Priming of cytotoxic T lymphocytes at various stages of ontogeny with transfectoma cells expressing a chimeric Ig heavy chain gene bearing an influenza virus nucleoprotein peptide.
International immunology 1993;5(10):1301-7.
1993: S Shibata; T Muryoi; Y Saitoh; Teodor-D Brumeanu; Constantin A Bona; KN Kasturi
Immunochemical and molecular characterization of anti-RNA polymerase I autoantibodies produced by tight skin mouse.
The Journal of clinical investigation 1993;92(2):984-92.
1993: KN Kasturi; C Daian; Y Saitoh; T Muryoi; Constantin A Bona
Tight-skin mouse autoantibody repertoire: analysis of VH and VK gene usage.
Molecular immunology 1993;30(11):969-78.
1993: H Kuzu; Y Kuzu; H Zaghouani; Constantin A Bona
In vivo priming effect during various stages of ontogeny of an influenza A virus nucleoprotein peptide.
European journal of immunology 1993;23(6):1397-400.
1993: S Shibata; Peter C Harpel; Constantin A Bona; H Fillit
Monoclonal antibodies to heparan sulfate inhibit the formation of thrombin-antithrombin III complexes.
Clinical immunology and immunopathology 1993;67(3 Pt 1):264-72.
1993: Teodor-D Brumeanu; Ronald A Kohanski; Constantin A Bona; H Zaghouani
A sensitive method to detect defined peptide among those eluted from murine MHC class II molecules.
Journal of immunological methods 1993;160(1):65-71.
1993: Peter Boros; T Muryoi; Harry Spiera; Constantin A Bona; J C Unkeless
Autoantibodies directed against different classes of Fc gamma R are found in sera of autoimmune patients.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(5):2018-24.
1993: H Zaghouani; R Steinman; R Nonacs; H Shah; W Gerhard; Constantin A Bona
Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule.
Science (New York, N.Y.) 1993;259(5092):224-7.
1993: L Dinca; S Neuwirth; J Schulman; Constantin A Bona
Induction of antihemagglutinin antibodies by polyclonal antiidiotype antibodies.
Viral immunology 1993;6(1):75-84.
1993: A Szegedi; Peter Boros; J Chen; M Kaffina; Constantin A Bona; J C Unkeless
An Fc gamma RIII (CD16)-specific autoantibody from a patient with progressive systemic sclerosis.
Immunology letters 1993;35(1):69-76.
1993: Constantin A Bona
Molecular characteristics of anti-polysaccharide antibodies.
Springer seminars in immunopathology 1993;15(2-3):103-18.
1993: H Zaghouani; Y Kuzo; H Kuzo; N Mann; C Daian; Constantin A Bona
Engineered immunoglobulin molecules as vehicles for T cell epitopes.
International reviews of immunology 1993;10(2-3):265-78.
1992: T Muryoi; J André-Schwartz; Y Saitoh; C Daian; B Hall; A Dimitriu-Bona; Robert S Schwartz; Constantin A Bona; KN Kasturi
Self-reactive repertoire of tight skin (TSK/+) mouse: immunochemical and molecular characterization of anti-cellular autoantibodies.
Cellular immunology 1992;144(1):43-54.
1992: B L Hall; H Zaghouani; C Daian; Constantin A Bona
A single amino acid mutation in CDR3 of the 3-14-9 L chain abolished expression of the IDA 10-defined idiotope and antigen binding.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1605-12.
1992: Constantin A Bona; A Nixon; R Kennedy; H Zaghouani
Adjuvanticity of stearyl tyrosine on the antibody response to peptide 503-535 from HIV gp160.
AIDS research and human retroviruses 1992;8(8):1377.
1992: H Zaghouani; M Krystal; H Kuzu; T Moran; H Shah; Y Kuzu; J Schulman; Constantin A Bona
Cells expressing an H chain Ig gene carrying a viral T cell epitope are lysed by specific cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(11):3604-9.
1992: T Muryoi; KN Kasturi; M J Kafina; D S Cram; L C Harrison; T Sasaki; Constantin A Bona
Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes.
The Journal of experimental medicine 1992;175(4):1103-9.
1992: A Nixon; H Zaghouani; C L Penney; M Lacroix; G Dionne; S A Anderson; R C Kennedy; Constantin A Bona
Adjuvanticity of stearyl tyrosine on the antibody response to peptide 503-535 from HIV gp160.
Viral immunology 1992;5(2):141-50.
1992: Constantin A Bona
Expression of V gene families during ontogeny and establishment of B cell repertoire.
International reviews of immunology 1992;8(2-3):83-94.
1991: KN Kasturi; Constantin A Bona
Analysis of the expression immunoglobulin gene repertoire by screening libraries derived from PCR-amplified cDNA.
Nucleic acids research 1991;19(22):6339-40.
1991: N C Bailey; KN Kasturi; T K Blackwell; F W Alt; Constantin A Bona
Complexity of the immunoglobulin light chain V kappa 1 gene family in the New Zealand black mouse.
International immunology 1991;3(8):751-60.
1991: H Zaghouani; D Goldstein; H Shah; S Anderson; M Lacroix; G Dionne; R Kennedy; Constantin A Bona
Induction of antibodies to the envelope protein of the human immunodeficiency virus by immunization with monoclonal anti-idiotypes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5645-9.
1991: Peter Boros; J A Odin; T Muryoi; Sandra K Masur; Constantin A Bona; J C Unkeless
IgM anti-Fc gamma R autoantibodies trigger neutrophil degranulation.
The Journal of experimental medicine 1991;173(6):1473-82.
1991: M H Bocchieri; P D Henriksen; KN Kasturi; T Muryoi; Constantin A Bona; Sergio A Jimenez
Evidence for autoimmunity in the tight skin mouse model of systemic sclerosis.
Arthritis and rheumatism 1991;34(5):599-605.
1991: N C Bailey; A Bona; Steven Dikman; F Bonilla; F W Alt; Constantin A Bona
Correlation between the occurrence of lupus nephritis, anti-erythrocyte autoantibodies and V kappa haplotype in NZB x 129/J and NZB x SM/J recombinant inbred murine strains.
European journal of immunology 1991;21(4):959-65.
1991: Azad Kaushik; Luc Reininger; Garnett Kelsoe; Jean-Claude Jaton; Constantin A Bona
Contribution of the VH11 gene family to mitogen-responsive B cell repertoire in C57BL/6 mice.
European journal of immunology 1991;21(3):827-30.
1991: Thomas M Moran; O Usuba; H Kuzu; Y Kuzu; J Schulman; Constantin A Bona
Inhibition of multicycle influenza virus replication by hybrid antibody-directed cytotoxic T lymphocyte lysis.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):321-6.
1991: H Zaghouani; B Hall; H Shah; Constantin A Bona
Immunogenicity of synthetic peptides corresponding to various epitopes of the human immunodeficiency virus envelope protein.
Advances in experimental medicine and biology 1991;303():53-62.
1991: R Mayer; K Stone; A Han; Constantin A Bona
Malignant CD5 B cells--biased immunoglobulin variable gene usage and autoantibody production.
International reviews of immunology 1991;7(3):189-203.
1991: T Muryoi; KN Kasturi; M J Kafina; Y Saitoh; O Usuba; JS Perlish; Raul Fleischmajer; Constantin A Bona
Self reactive repertoire of tight skin mouse: immunochemical and molecular characterization of anti-topoisomerase I autoantibodies.
Autoimmunity 1991;9(2):109-17.
1990: Azad Kaushik; R Mayer; V Fidanza; H Zaghouani; A Lim; Constantin A Bona; Guillaume Dighiero
Ly1 and V-gene expression among hybridomas secreting natural autoantibody.
Journal of autoimmunity 1990;3(6):687-700.
1990: KN Kasturi; R Mayer; Constantin A Bona; V E Scott; C L Sidman
Germline V genes encode viable motheaten mouse autoantibodies against thymocytes and red blood cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(7):2304-11.
1990: O Usuba; M Ito; Constantin A Bona; Thomas M Moran
Antibody-mediated redirected cytolysis against murine melanoma cells in vivo.
Cancer research 1990;50(18):6034-8.
1990: Constantin A Bona; Y Saitoh; Garnett Kelsoe
Pairing of VK and VK gene families in self-reactive antibodies.
Journal of clinical immunology 1990;10(5):223-36.
1990: F A Bonilla; H Zaghouani; M Rubin; Constantin A Bona
V kappa gene usage, idiotype expression, and antigen binding among clones expressing the VHX24 gene family derived from naive and anti-idiotype immune BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(2):616-22.
1990: Azad Kaushik; Dan H Schulze; F A Bonilla; Constantin A Bona; Garnett Kelsoe
Stochastic pairing of heavy-chain and kappa light-chain variable gene families occurs in polyclonally activated B cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):4932-6.
1990: A Nixon-George; T Moran; G Dionne; C L Penney; D Lafleur; Constantin A Bona
The adjuvant effect of stearyl tyrosine on a recombinant subunit hepatitis B surface antigen.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4798-802.
1990: Thomas M Moran; O Usuba; E Shapiro; L J Rubinstein; M Ito; Constantin A Bona
A novel technique for the production of hybrid antibodies.
Journal of immunological methods 1990;129(2):199-205.
1990: V Fidanza; R Mayer; H Zaghouani; M A DiLiberti; Constantin A Bona
Autoantibodies, LY-1, and immunoglobulin V gene expression in hybridomas obtained from young and from old New Zealand black mice.
Arthritis and rheumatism 1990;33(5):711-23.
1990: Peter Boros; J M Chen; Constantin A Bona; J C Unkeless
Autoimmune mice make anti-Fc gamma receptor antibodies.
The Journal of experimental medicine 1990;171(5):1581-95.
1990: B Hall; Constantin A Bona; C Victor-Kobrin
Binding specificities of inulin-binding immunoglobulins for sinistrin and oligosaccharides isolated from asparagus roots.
Molecular immunology 1990;27(4):351-61.
1990: C Victor-Kobrin; Z T Barak; F A Bonilla; B Kobrin; I Sanz; D French; J Rothe; Constantin A Bona
A molecular and structural analysis of the VH and VK regions of monoclonal antibodies bearing the A48 regulatory idiotype.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(2):614-24.
1990: F A Bonilla; H Zaghouani; Constantin A Bona
Patterns of idiotypic similarity and their structural bases among antibodies specific for foreign or self antigens.
Chemical immunology 1990;48():49-62.
1990: O Usuba; Jerome L Schulman; A M Deatly; Constantin A Bona; Thomas M Moran
New method for titration of virus infectivity by immunostaining.
Viral immunology 1990;3(3):237-41.
1990: R Mayer; H Zaghouani; O Usuba; Constantin A Bona
The LY-1 gene expression in murine hybridomas producing autoantibodies.
Autoimmunity 1990;6(4):293-305.
1989: N C Bailey; V Fidanza; R Mayer; G Mazza; M Fougereau; Constantin A Bona
Activation of clones producing self-reactive antibodies by foreign antigen and antiidiotype antibody carrying the internal image of the antigen.
The Journal of clinical investigation 1989;84(3):744-56.
1989: H Zaghouani; V Fidanza; Constantin A Bona
The significance of idiotype-anti-idiotype interactions in the activation of self-reactive clones.
Clinical and experimental rheumatology 1989;7 Suppl 3():S19-25.
1989: C Victor-Kobrin; F A Bonilla; Z Barak; Constantin A Bona
Structural correlates of a regulatory idiotope.
Immunological reviews 1989;110():151-71.
1989: M Ito; O Usuba; J C Unkeless; R Schreiber; F Celada; Constantin A Bona; Thomas M Moran
Sideways killing: the cytolysis of Fc receptor-bearing cells through bridging to cytolytic T lymphocytes by antibodies specific for the T-cell receptor-T3 complex.
Scandinavian journal of immunology 1989;29(6):659-69.
1989: Azad Kaushik; Dan H Schulze; Constantin A Bona; Garnett Kelsoe
Murine V kappa gene expression does not follow the VH paradigm.
The Journal of experimental medicine 1989;169(5):1859-64.
1989: H Zaghouani; F A Bonilla; K Meek; Constantin A Bona
Molecular basis for expression of the A48 regulatory idiotope on antibodies encoded by immunoglobulin variable-region genes from various families.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2341-5.
1989: C Victor-Kobrin; Constantin A Bona
The molecular origin of regulatory idiotypes.
International reviews of immunology 1989;5(2):117-29.
1989: C Victor-Kobrin; Z Barak; J Rothe; L J Rubinstein; Constantin A Bona
The role of the A48 regulatory idiotype in inducing tumor-specific immunity.
International reviews of immunology 1989;4(4):321-36.
1989: F A Bonilla; R S Anderson; M Z Atassi; Constantin A Bona
A Vh region synthetic peptide induces antibodies which bind native immunoglobulins and augment an immune response to antigen.
Advances in experimental medicine and biology 1989;251():129-43.
1989: Constantin A Bona
Idiotype network theory and its implications in anti-tumor immunity.
Progress in clinical and biological research 1989;288():215-21.
1988: C J Painter; Marc Monestier; A Chew; A Bona-Dimitriu; KN Kasturi; C Bailey; V E Scott; C L Sidman; Constantin A Bona
Specificities and V genes encoding monoclonal autoantibodies from viable motheaten mice.
The Journal of experimental medicine 1988;167(3):1137-53.
1988: Marc Monestier; Constantin A Bona
Antibodies possessing multiple antigen specificities and exhibiting extensive idiotypic cross-reactivity.
International reviews of immunology 1988;3(1-2):59-70.
1988: KN Kasturi; Marc Monestier; R Mayer; Constantin A Bona
Biased usage of certain Vk gene families by autoantibodies and their polymorphism in autoimmune mice.
Molecular immunology 1988;25(2):213-9.
1988: Constantin A Bona; KN Kasturi; R Mayer; V Fidanza
V genes usage by autoantibodies and their polymorphism in autoimmune mice.
Autoimmunity 1988;2(1):39-53.
1988: Constantin A Bona
Genes regulating rheumatoid factors.
Springer seminars in immunopathology 1988;10(1):57-65.
1988: N C Bailey; Marc Monestier; Constantin A Bona
Immunochemical and molecular properties of antibodies exhibiting binding properties to glutamic acid-tyrosine homopolymer and to self antigens.
Annals of the New York Academy of Sciences 1988;546():63-71.
1988: S J Waters; Constantin A Bona
Characterization of a T-cell clone recognizing idiotypes as tumor-associated antigens.
Cellular immunology 1988;111(1):87-93.
1988: Constantin A Bona
V genes encoding autoantibodies: molecular and phenotypic characteristics.
Annual review of immunology 1988;6():327-58.
1987: M Ito; G G Fredrickson; F Celada; Jerome L Schulman; Constantin A Bona; Thomas M Moran
Methods for the selection and growth of antigen-specific cytolytic T lines and clones bearing a defined T cell receptor beta chain marker.
Journal of immunological methods 1987;103(2):229-37.
1987: R S Quartin; Marc Monestier; Thomas M Moran; S J Waters; G G Fredrickson; Constantin A Bona
Characterization of the fine specificity and antigen markers associated with the receptor of autoreactive T-cell hybridomas.
Cellular immunology 1987;110(1):163-75.
1987: Marc Monestier; B Bonin; P Migliorini; H Dang; S Datta; R Kuppers; Noel R Rose; P Maurer; N Talal; Constantin A Bona
Autoantibodies of various specificities encoded by genes from the VH J558 family bind to foreign antigens and share idiotopes of antibodies specific for self and foreign antigens.
The Journal of experimental medicine 1987;166(4):1109-24.
1987: B E Johansson; Thomas M Moran; Constantin A Bona; S W Popple; Edwin D Kilbourne
Immunologic response to influenza virus neuraminidase is influenced by prior experience with the associated viral hemagglutinin. II. Sequential infection of mice simulates human experience.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(6):2010-4.
1987: B E Johansson; Thomas M Moran; Constantin A Bona; Edwin D Kilbourne
Immunologic response to influenza virus neuraminidase is influenced by prior experience with the associated viral hemagglutinin. III. Reduced generation of neuraminidase-specific helper T cells in hemagglutinin-primed mice.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(6):2015-9.
1987: B Bellon; A Manheimer-Lory; Marc Monestier; T Moran; A Dimitriu-Bona; F Alt; Constantin A Bona
High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains.
The Journal of clinical investigation 1987;79(4):1044-53.
1987: R Mayer; C Ioannides; T Moran; B Johansson; Constantin A Bona
Effect of syngeneic anti-idiotypic antibody on influenza virus neuraminidase antibody response.
Viral immunology 1987;1(2):121-34.
1987: Thomas M Moran; Marc Monestier; Alexander Lai; G Norton; M A Reale; M A Thompson; Jerome L Schulman; R Riblet; Constantin A Bona
Characterization of variable-region genes and shared crossreactive idiotypes of antibodies specific for antigens of various influenza viruses.
Viral immunology 1987;1(1):1-12.
1987: Jerome L Schulman; Thomas M Moran; M Reale; Y Beilin; N Sigal; Constantin A Bona
Effects of immunization with syngeneic monoclonal anti-idiotype antibody on antibody responses to influenza viruses.
Monographs in allergy 1987;22():143-9.
1987: Nolan Sigal; M Chan; M A Reale; T Moran; Jerome L Schulman; Constantin A Bona
Idiotypic analysis of the influenza virus-specific human B cell repertoire.
Monographs in allergy 1987;22():134-42.
1987: A J Manheimer-Lory; Marc Monestier; B Bellon; Constantin A Bona
Autoantibodies: restricted use of VH gene families and idiotype cross-reactivity.
Monographs in allergy 1987;22():38-45.
1986: C Painter; Marc Monestier; B Bonin; Constantin A Bona
Functional and molecular studies of V genes expressed in autoantibodies.
Immunological reviews 1986;94():75-98.
1986: A J Manheimer-Lory; Marc Monestier; B Bellon; F W Alt; Constantin A Bona
Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(21):8293-7.
1986: M A Reale; A J Manheimer; Thomas M Moran; G Norton; Constantin A Bona; Jerome L Schulman
Characterization of monoclonal antibodies specific for sequential influenza A/PR/8/34 virus variants.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(4):1352-8.
1986: C Victor-Kobrin; F A Bonilla; Constantin A Bona
An immunochemical and molecular analysis of monoclonal antibodies bearing the A48 regulatory idiotype.
The Mount Sinai journal of medicine, New York 1986;53(3):187-93.
1986: Constantin A Bona; C Victor-Kobrin
Questions related to a functional idiotype-network.
Annales de l'Institut Pasteur. Immunologie 1986;137C(1):87-90.
1986: Thomas M Moran; M A Reale; Marc Monestier; R Mayer; Jerome L Schulman; Constantin A Bona
Idiotypy of anti-influenza virus immune responses.
Concepts in immunopathology 1986;3():233-52.
1986: Marc Monestier; B Bellon; A J Manheimer; Constantin A Bona
Rheumatoid factors. Immunochemical, molecular, and regulatory properties.
Annals of the New York Academy of Sciences 1986;475():106-13.
1985: C Victor-Kobrin; F A Bonilla; B Bellon; Constantin A Bona
Immunochemical and molecular characterization of regulatory idiotopes expressed by monoclonal antibodies exhibiting or lacking beta 2-6 fructosan binding activity.
The Journal of experimental medicine 1985;162(2):647-62.
1985: M A Reale; Constantin A Bona; Jerome L Schulman
Isotype profiles of anti-influenza antibodies in mice bearing the xid defect.
Journal of virology 1985;53(2):425-9.
1984: A J Manheimer; C Victor-Kobrin; K E Stein; Constantin A Bona
Anti-immunoglobulin antibodies. V. Age-dependent variation of clones stimulated by polysaccharide TI-2 antigens in 129 and MRL mice spontaneously producing anti-gamma-globulin antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(2):562-8.
1984: Constantin A Bona; C Victor-Kobrin; A J Manheimer; B Bellon; L J Rubinstein
Regulatory arms of the immune network.
Immunological reviews 1984;79():25-44.
1984: C Victor-Kobrin; Constantin A Bona; B Pernis
Expansion of idiotype positive B cells in maternally idiotype suppressed mice.
The Journal of molecular and cellular immunology : JMCI 1984;1(6):331-46.