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Thomas Südhof

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
53
Rizo, Josep
47
Jahn, Reinhard
21
Geppert, Martin
20
Hammer, Robert
18
Liu, Xinran
17
Shin, Ok-Ho
16
Khvotchev, Mikhail
15
Missler, Markus
15
Dulubova, Irina
15
rosenmund, christian
12
Sugita, Shuzo
11
Davletov, Bazbek
11
Brose, Nils
11
Kavalali, Ege
10
Maximov, Anton

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Publications

TOP 3
Gibson Jay R; Huber Kimberly M; Südhof Thomas C
Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.
Kaeser Pascal S; Deng Lunbin; Chávez Andrés E; Liu Xinran; Castillo Pablo E; Südhof Thomas C
ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses.
Etherton Mark R; Blaiss Cory A; Powell Craig M; Südhof Thomas C
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments.

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All Publications

2009: Gibson Jay R; Huber Kimberly M; Südhof Thomas C
Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(44):13883-97.
2009: Kaeser Pascal S; Deng Lunbin; Chávez Andrés E; Liu Xinran; Castillo Pablo E; Südhof Thomas C
ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses.
Neuron 2009;64(2):227-39.
2009: Etherton Mark R; Blaiss Cory A; Powell Craig M; Südhof Thomas C
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17998-8003.
2009: Ko Jaewon; Zhang Chen; Arac Demet; Boucard Antony A; Brunger Axel T; Südhof Thomas C
Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation.
The EMBO journal 2009;28(20):3244-55.
2009: Shin Ok-Ho; Xu Jun; Rizo Josep; Südhof Thomas C
Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16469-74.
2009: Zhang Chen; Milunsky Jeff M; Newton Stephanie; Ko Jaewon; Zhao Geping; Maher Tom A; Tager-Flusberg Helen; Bolliger Marc F; Carter Alice S; Boucard Antony A; Powell Craig M; Südhof Thomas C
A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(35):10843-54.
2009: Zhang Chen; Wu Bei; Beglopoulos Vassilios; Wines-Samuelson Mary; Zhang Dawei; Dragatsis Ioannis; Südhof Thomas C; Shen Jie
Presenilins are essential for regulating neurotransmitter release.
Nature 2009;460(7255):632-6.
2009: Deák Ferenc; Liu Xinran; Khvotchev Mikhail; Li Gang; Kavalali Ege T; Sugita Shuzo; Südhof Thomas C
Alpha-latrotoxin stimulates a novel pathway of Ca2+-dependent synaptic exocytosis independent of the classical synaptic fusion machinery.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(27):8639-48.
2009: Tabuchi Katsuhiko; Chen Guiquan; Südhof Thomas C; Shen Jie
Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(22):7290-301.
2009: Xu Jun; Pang Zhiping P; Shin Ok-Ho; Südhof Thomas C
Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release.
Nature neuroscience 2009;12(6):759-66.
2009: Deák Ferenc; Xu Yi; Chang Wen-Pin; Dulubova Irina; Khvotchev Mikhail; Liu Xinran; Südhof Thomas C; Rizo Josep
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming.
The Journal of cell biology 2009;184(5):751-64.
2009: Gustavsson Natalia; Wei Shun-Hui; Hoang Dong Nhut; Lao Ye; Zhang Quan; Radda George K; Rorsman Patrik; Südhof Thomas C; Han Weiping
Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas.
The Journal of physiology 2009;587(Pt 6):1169-78.
2009: Blundell J; Tabuchi K; Bolliger M F; Blaiss C A; Brose N; Liu X; Südhof T C; Powell C M
Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2.
Genes, brain, and behavior 2009;8(1):114-26.
2009: Chang Wen-Pin; Südhof Thomas C
SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(4):883-97.
2009: Maximov Anton; Tang Jiong; Yang Xiaofei; Pang Zhiping P; Südhof Thomas C
Complexin controls the force transfer from SNARE complexes to membranes in fusion.
Science (New York, N.Y.) 2009;323(5913):516-21.
2009: Südhof Thomas C; Rothman James E
Membrane fusion: grappling with SNARE and SM proteins.
Science (New York, N.Y.) 2009;323(5913):474-7.
2008: Ho Angela; Liu Xinran; Südhof Thomas C
Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(53):14392-400.
2008: Südhof Thomas C; Malenka Robert C
Understanding synapses: past, present, and future.
Neuron 2008;60(3):469-76.
2008: Südhof Thomas C
Neuroligins and neurexins link synaptic function to cognitive disease.
Nature 2008;455(7215):903-11.
2008: Kaeser Pascal S; Kwon Hyung-Bae; Blundell Jacqueline; Chevaleyre Vivien; Morishita Wade; Malenka Robert C; Powell Craig M; Castillo Pablo E; Südhof Thomas C
RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14680-5.
2008: Gerber Stefan H; Rah Jong-Cheol; Min Sang-Won; Liu Xinran; de Wit Heidi; Dulubova Irina; Meyer Alexander C; Rizo Josep; Arancillo Marife; Hammer Robert E; Verhage Matthijs; Rosenmund Christian; Südhof Thomas C
Conformational switch of syntaxin-1 controls synaptic vesicle fusion.
Science (New York, N.Y.) 2008;321(5895):1507-10.
2008: Bolliger Marc F; Pei Jimin; Maxeiner Stephan; Boucard Antony A; Grishin Nick V; Südhof Thomas C
Unusually rapid evolution of Neuroligin-4 in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(17):6421-6.
2008: Mukherjee Konark; Sharma Manu; Urlaub Henning; Bourenkov Gleb P; Jahn Reinhard; Südhof Thomas C; Wahl Markus C
CASK Functions as a Mg2+-independent neurexin kinase.
Cell 2008;133(2):328-39.
2008: Gustavsson Natalia; Lao Ye; Maximov Anton; Chuang Jen-Chieh; Kostromina Elena; Repa Joyce J; Li Cai; Radda George K; Südhof Thomas C; Han Weiping
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3992-7.
2008: Maximov Anton; Lao Ye; Li Hongmei; Chen Xiaocheng; Rizo Josep; Sørensen Jakob B; Südhof Thomas C
Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3986-91.
2008: Schonn Jean-Sébastien; Maximov Anton; Lao Ye; Südhof Thomas C; Sørensen Jakob B
Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3998-4003.
2008: Gallardo Gilbert; Schlüter Oliver M; Südhof Thomas C
A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.
Nature neuroscience 2008;11(3):301-8.
2007: Araç Demet; Boucard Antony A; Ozkan Engin; Strop Pavel; Newell Evan; Südhof Thomas C; Brunger Axel T
Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactions.
Neuron 2007;56(6):992-1003.
2007: Sun Jianyuan; Pang Zhiping P; Qin Dengkui; Fahim Abigail T; Adachi Roberto; Südhof Thomas C
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse.
Nature 2007;450(7170):676-82.
2007: Khvotchev Mikhail; Dulubova Irina; Sun Jianyuan; Dai Han; Rizo Josep; Südhof Thomas C
Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(45):12147-55.
2007: Tabuchi Katsuhiko; Blundell Jacqueline; Etherton Mark R; Hammer Robert E; Liu Xinran; Powell Craig M; Südhof Thomas C
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice.
Science (New York, N.Y.) 2007;318(5847):71-6.
2007: Südhof Thomas C
Membrane fusion as a team effort.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13541-2.
2007: Wu Hao; Xu Jun; Pang Zhiping P; Ge Weihong; Kim Kevin J; Blanchi Bruno; Chen Caifu; Südhof Thomas C; Sun Yi E
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13821-6.
2007: Guan Rong; Dai Han; Tomchick Diana R; Dulubova Irina; Machius Mischa; Südhof Thomas C; Rizo Josep
Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution.
Biochemistry 2007;46(31):8988-98.
2007: Bronk Peter; Deák Ferenc; Wilson Michael C; Liu Xinran; Südhof Thomas C; Kavalali Ege T
Differential effects of SNAP-25 deletion on Ca2+ -dependent and Ca2+ -independent neurotransmission.
Journal of neurophysiology 2007;98(2):794-806.
2007: Chubykin Alexander A; Atasoy Deniz; Etherton Mark R; Brose Nils; Kavalali Ege T; Gibson Jay R; Südhof Thomas C
Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2.
Neuron 2007;54(6):919-31.
2007: Chevaleyre Vivien; Heifets Boris D; Kaeser Pascal S; Südhof Thomas C; Castillo Pablo E
Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alpha.
Neuron 2007;54(5):801-12.
2007: Xu Jun; Mashimo Tomoyuki; Südhof Thomas C
Synaptotagmin-1, -2, and -9: Ca(2+) sensors for fast release that specify distinct presynaptic properties in subsets of neurons.
Neuron 2007;54(4):567-81.
2007: Dudanova Irina; Tabuchi Katsuhiko; Rohlmann Astrid; Südhof Thomas C; Missler Markus
Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.
The Journal of comparative neurology 2007;502(2):261-74.
2007: Min Sang-Won; Chang Wen-Pin; Südhof Thomas C
E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3823-8.
2007: Nicol Xavier; Voyatzis Sylvie; Muzerelle Aude; Narboux-Nême Nicolas; Südhof Thomas C; Miles Richard; Gaspar Patricia
cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map.
Nature neuroscience 2007;10(3):340-7.
2007: Maximov Anton; Pang Zhiping P; Tervo Dougal G R; Südhof Thomas C
Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation.
Journal of neuroscience methods 2007;161(1):75-87.
2007: Dulubova Irina; Khvotchev Mikhail; Liu Siqi; Huryeva Iryna; Südhof Thomas C; Rizo Josep
Munc18-1 binds directly to the neuronal SNARE complex.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2697-702.
2007: Atasoy Deniz; Schoch Susanne; Ho Angela; Nadasy Krisztina A; Liu Xinran; Zhang Weiqi; Mukherjee Konark; Nosyreva Elena D; Fernandez-Chacon Rafael; Missler Markus; Kavalali Ege T; Südhof Thomas C
Deletion of CASK in mice is lethal and impairs synaptic function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2525-30.
2007: Maximov Anton; Shin Ok-Ho; Liu Xinran; Südhof Thomas C
Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release.
The Journal of cell biology 2007;176(1):113-24.
2006: Pang Zhiping P; Melicoff Ernestina; Padgett Daniel; Liu Yun; Teich Andrew F; Dickey Burton F; Lin Weichun; Adachi Roberto; Südhof Thomas C
Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(52):13493-504.
2006: Ho Angela; Morishita Wade; Atasoy Deniz; Liu Xinran; Tabuchi Katsuhiko; Hammer Robert E; Malenka Robert C; Südhof Thomas C
Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(50):13089-101.
2006: Juranek Judyta; Mukherjee Konark; Rickmann Michael; Martens Henrik; Calka Jaroslaw; Südhof Thomas C; Jahn Reinhard
Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification.
The European journal of neuroscience 2006;24(11):3043-52.
2006: Schoch Susanne; Mittelstaedt Tobias; Kaeser Pascal S; Padgett Daniel; Feldmann Nicole; Chevaleyre Vivien; Castillo Pablo E; Hammer Robert E; Han Weiping; Schmitz Frank; Lin Weichun; Südhof Thomas C
Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
The EMBO journal 2006;25(24):5852-63.
2006: Pang Zhiping P; Shin Ok-Ho; Meyer Alexander C; Rosenmund Christian; Südhof Thomas C
A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(48):12556-65.
2006: Südhof Thomas C
Synaptic vesicles: an organelle comes of age.
Cell 2006;127(4):671-3.
2006: Comoletti Davide; Flynn Robyn E; Boucard Antony A; Demeler Borries; Schirf Virgil; Shi Jianxin; Jennings Lori L; Newlin Helen R; Südhof Thomas C; Taylor Palmer
Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins.
Biochemistry 2006;45(42):12816-27.
2006: Tang Jiong; Maximov Anton; Shin Ok-Ho; Dai Han; Rizo Josep; Südhof Thomas C
A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis.
Cell 2006;126(6):1175-87.
2006: Varoqueaux Frédérique; Aramuni Gayane; Rawson Randi L; Mohrmann Ralf; Missler Markus; Gottmann Kurt; Zhang Weiqi; Südhof Thomas C; Brose Nils
Neuroligins determine synapse maturation and function.
Neuron 2006;51(6):741-54.
2006: Sheckler Lauren R; Henry Lisa; Sugita Shuzo; Südhof Thomas C; Rudenko Gabby
Crystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+ binding and the effects of alternative splicing.
The Journal of biological chemistry 2006;281(32):22896-905.
2006: Lu Jun; Machius Mischa; Dulubova Irina; Dai Han; Südhof Thomas C; Tomchick Diana R; Rizo Josep
Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.
PLoS biology 2006;4(7):e192.
2006: Deák Ferenc; Shin Ok-Ho; Kavalali Ege T; Südhof Thomas C
Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(25):6668-76.
2006: Deák Ferenc; Shin Ok-Ho; Tang Jiong; Hanson Phyllis; Ubach Josep; Jahn Reinhard; Rizo Josep; Kavalali Ege T; Südhof Thomas C
Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion.
The EMBO journal 2006;25(12):2856-66.
2006: Li LiYi; Shin Ok-Ho; Rhee Jeong-Seop; Araç Demet; Rah Jong-Cheol; Rizo Josep; Südhof Thomas; Rosenmund Christian
Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.
The Journal of biological chemistry 2006;281(23):15845-52.
2006: Pang Zhiping P; Sun Jianyuan; Rizo Josep; Maximov Anton; Südhof Thomas C
Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release.
The EMBO journal 2006;25(10):2039-50.
2006: Araç Demet; Chen Xiaocheng; Khant Htet A; Ubach Josep; Ludtke Steven J; Kikkawa Masahide; Johnson Arthur E; Chiu Wah; Südhof Thomas C; Rizo Josep
Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids.
Nature structural & molecular biology 2006;13(3):209-17.
2006: Sun Jianyuan; Bronk Peter; Liu Xinran; Han Weiping; Südhof Thomas C
Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2880-5.
2006: Schmitz Frank; Tabares Lucia; Khimich Darina; Strenzke Nicola; de la Villa-Polo Pedro; Castellano-Muñoz Manuel; Bulankina Anna; Moser Tobias; Fernández-Chacón Rafael; Südhof Thomas C
CSPalpha-deficiency causes massive and rapid photoreceptor degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(8):2926-31.
2006: Schlüter Oliver M; Basu Jayeeta; Südhof Thomas C; Rosenmund Christian
Rab3 superprimes synaptic vesicles for release: implications for short-term synaptic plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(4):1239-46.
2006: Nagy Gábor; Kim Jun Hee; Pang Zhiping P; Matti Ulf; Rettig Jens; Südhof Thomas C; Sørensen Jakob B
Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(2):632-43.
2005: Rhee J-S; Li L Y; Shin O-H; Rah J-C; Rizo J; Südhof T C; Rosenmund C
Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18664-9.
2005: Kaeser P S; Südhof T C
RIM function in short- and long-term synaptic plasticity.
Biochemical Society transactions 2005;33(Pt 6):1345-9.
2005: Maximov Anton; Südhof Thomas C
Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release.
Neuron 2005;48(4):547-54.
2005: Chandra Sreeganga; Gallardo Gilbert; Fernández-Chacón Rafael; Schlüter Oliver M; Südhof Thomas C
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration.
Cell 2005;123(3):383-96.
2005: Boucard Antony A; Chubykin Alexander A; Comoletti Davide; Taylor Palmer; Südhof Thomas C
A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins.
Neuron 2005;48(2):229-36.
2005: Dai Han; Tomchick Diana R; García Jesús; Südhof Thomas C; Machius Mischa; Rizo Josep
Crystal structure of the RIM2 C2A-domain at 1.4 A resolution.
Biochemistry 2005;44(41):13533-42.
2005: Lu Jun; Li Hongmei; Wang Yun; Südhof Thomas C; Rizo Josep
Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide.
Journal of molecular biology 2005;352(2):455-66.
2005: Shah Sanjiv; Lee Sheu-Fen; Tabuchi Katsuhiko; Hao Yi-Heng; Yu Cong; LaPlant Quincey; Ball Haydn; Dann Charles E; Südhof Thomas; Yu Gang
Nicastrin functions as a gamma-secretase-substrate receptor.
Cell 2005;122(3):435-47.
2005: Dulubova Irina; Lou Xuelin; Lu Jun; Huryeva Iryna; Alam Amer; Schneggenburger Ralf; Südhof Thomas C; Rizo Josep
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
The EMBO journal 2005;24(16):2839-50.
2005: Huang Yan-You; Zakharenko Stanislav S; Schoch Susanne; Kaeser Pascal S; Janz Roger; Südhof Thomas C; Siegelbaum Steven A; Kandel Eric R
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9365-70.
2005: Toonen Ruud F G; de Vries Klaas Jan; Zalm Robbert; Südhof Thomas C; Verhage Matthijs
Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation.
Journal of neurochemistry 2005;93(6):1393-400.
2005: Borisovska Maria; Zhao Ying; Tsytsyura Yaroslav; Glyvuk Nataliya; Takamori Shigeo; Matti Ulf; Rettig Jens; Südhof Thomas; Bruns Dieter
v-SNAREs control exocytosis of vesicles from priming to fusion.
The EMBO journal 2005;24(12):2114-26.
2005: Chubykin Alexander A; Liu Xinran; Comoletti Davide; Tsigelny Igor; Taylor Palmer; Südhof Thomas C
Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism.
The Journal of biological chemistry 2005;280(23):22365-74.
2005: Zhang Weiqi; Rohlmann Astrid; Sargsyan Vardanush; Aramuni Gayane; Hammer Robert E; Südhof Thomas C; Missler Markus
Extracellular domains of alpha-neurexins participate in regulating synaptic transmission by selectively affecting N- and P/Q-type Ca2+ channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(17):4330-42.
2005: Südhof Thomas C
CAPS in search of a lost function.
Neuron 2005;46(1):2-4.
2005: Fornai Francesco; Schlüter Oliver M; Lenzi Paola; Gesi Marco; Ruffoli Riccardo; Ferrucci Michela; Lazzeri Gloria; Busceti Carla L; Pontarelli Fabrizio; Battaglia Giuseppe; Pellegrini Antonio; Nicoletti Ferdinando; Ruggieri Stefano; Paparelli Antonio; Südhof Thomas C
Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3413-8.
2005: Han Weiping; Rhee Jeong-Seop; Maximov Anton; Lin Weichun; Hammer Robert E; Rosenmund Christian; Südhof Thomas C
C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1.
The Journal of biological chemistry 2005;280(6):5089-100.
2005: Sara Yildirim; Biederer Thomas; Atasoy Deniz; Chubykin Alexander; Mozhayeva Marina G; Südhof Thomas C; Kavalali Ege T
Selective capability of SynCAM and neuroligin for functional synapse assembly.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(1):260-70.
2005: Shin Ok-Ho; Han Weiping; Wang Yun; Südhof Thomas C
Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties.
The Journal of biological chemistry 2005;280(2):1641-51.
2004: Khvotchev Mikhail V; Südhof Thomas C
Stimulus-dependent dynamic homo- and heteromultimerization of synaptobrevin/VAMP and synaptophysin.
Biochemistry 2004;43(47):15037-43.
2004: Deák Ferenc; Schoch Susanne; Liu Xinran; Südhof Thomas C; Kavalali Ege T
Synaptobrevin is essential for fast synaptic-vesicle endocytosis.
Nature cell biology 2004;6(11):1102-8.
2004: Khvotchev Mikhail; Südhof Thomas C
Proteolytic processing of amyloid-beta precursor protein by secretases does not require cell surface transport.
The Journal of biological chemistry 2004;279(45):47101-8.
2004: Chandra Sreeganga; Fornai Francesco; Kwon Hyung-Bae; Yazdani Umar; Atasoy Deniz; Liu Xinran; Hammer Robert E; Battaglia Giuseppe; German Dwight C; Castillo Pablo E; Südhof Thomas C
Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(41):14966-71.
2004: Dai Han; Shin Ok-Ho; Machius Mischa; Tomchick Diana R; Südhof Thomas C; Rizo Josep
Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4.
Nature structural & molecular biology 2004;11(9):844-9.
2004: Dulubova Irina; Ho Angela; Huryeva Iryna; Südhof Thomas C; Rizo Josep
Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein.
Biochemistry 2004;43(30):9583-8.
2004: Schlüter Oliver M; Schmitz Frank; Jahn Reinhard; Rosenmund Christian; Südhof Thomas C
A complete genetic analysis of neuronal Rab3 function.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6629-37.
2004: Calakos Nicole; Schoch Susanne; Südhof Thomas C; Malenka Robert C
Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release.
Neuron 2004;42(6):889-96.
2004: Cao Xinwei; Südhof Thomas C
Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.
The Journal of biological chemistry 2004;279(23):24601-11.
2004: Fernández-Chacón Rafael; Wölfel Markus; Nishimune Hiroshi; Tabares Lucia; Schmitz Frank; Castellano-Muñoz Manuel; Rosenmund Christian; Montesinos Maria L; Sanes Joshua R; Schneggenburger Ralf; Südhof Thomas C
The synaptic vesicle protein CSP alpha prevents presynaptic degeneration.
Neuron 2004;42(2):237-51.
2004: Powell Craig M; Schoch Susanne; Monteggia Lisa; Barrot Michel; Matos Maria F; Feldmann Nicole; Südhof Thomas C; Nestler Eric J
The presynaptic active zone protein RIM1alpha is critical for normal learning and memory.
Neuron 2004;42(1):143-53.
2004: Li Qiming; Südhof Thomas C
Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.
The Journal of biological chemistry 2004;279(11):10542-50.
2004: Kattenstroth Gunnar; Tantalaki Evangelia; Südhof Thomas C; Gottmann Kurt; Missler Markus
Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2607-12.
2004: Shin Ok-Ho; Maximov Anton; Lim Byung Kook; Rizo Josep; Südhof Thomas C
Unexpected Ca2+-binding properties of synaptotagmin 9.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2554-9.
2004: Ho Angela; Südhof Thomas C
Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2548-53.
2004: Garcia Jesus; Gerber Stefan H; Sugita Shuzo; Südhof Thomas C; Rizo Josep
A conformational switch in the Piccolo C2A domain regulated by alternative splicing.
Nature structural & molecular biology 2004;11(1):45-53.
2004: Han Weiping; Rhee Jeong-Seop; Maximov Anton; Lao Ye; Mashimo Tomoyuki; Rosenmund Christian; Südhof Thomas C
N-glycosylation is essential for vesicular targeting of synaptotagmin 1.
Neuron 2004;41(1):85-99.
2003: Comoletti Davide; Flynn Robyn; Jennings Lori L; Chubykin Alexander; Matsumura Takehito; Hasegawa Hana; Südhof Thomas C; Taylor Palmer
Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta.
The Journal of biological chemistry 2003;278(50):50497-505.
2003: Khvotchev Mikhail V; Ren Mindong; Takamori Shigeo; Jahn Reinhard; Südhof Thomas C
Divergent functions of neuronal Rab11b in Ca2+-regulated versus constitutive exocytosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(33):10531-9.
2003: Matos Maria F; Mukherjee Konark; Chen Xiaocheng; Rizo Josep; Südhof Thomas C
Evidence for SNARE zippering during Ca2+-triggered exocytosis in PC12 cells.
Neuropharmacology 2003;45(6):777-86.
2003: Virmani Tuhin; Han Weiping; Liu Xinran; Südhof Thomas C; Kavalali Ege T
Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling.
The EMBO journal 2003;22(20):5347-57.
2003: Lonart György; Schoch Susanne; Kaeser Pascal S; Larkin C Jenny; Südhof Thomas C; Linden David J
Phosphorylation of RIM1alpha by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses.
Cell 2003;115(1):49-60.
2003: Sørensen Jakob B; Fernández-Chacón Rafael; Südhof Thomas C; Neher Erwin
Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+.
The Journal of general physiology 2003;122(3):265-76.
2003: Missler Markus; Zhang Weiqi; Rohlmann Astrid; Kattenstroth Gunnar; Hammer Robert E; Gottmann Kurt; Südhof Thomas C
Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.
Nature 2003;423(6943):939-48.
2003: Chandra Sreeganga; Chen Xiaocheng; Rizo Josep; Jahn Reinhard; Südhof Thomas C
A broken alpha -helix in folded alpha -Synuclein.
The Journal of biological chemistry 2003;278(17):15313-8.
2003: Wang Yun; Südhof Thomas C
Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins( small star, filled ).
Genomics 2003;81(2):126-37.
2003: Jahn Reinhard; Lang Thorsten; Südhof Thomas C
Membrane fusion.
Cell 2003;112(4):519-33.
2003: Shin Ok-Ho; Rhee Jeong-Seop; Tang Jiong; Sugita Shuzo; Rosenmund Christian; Südhof Thomas C
Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions.
Neuron 2003;37(1):99-108.
2003: Schlüter O M; Fornai F; Alessandrí M G; Takamori S; Geppert M; Jahn R; Südhof T C
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Neuroscience 2003;118(4):985-1002.
2002: Wang Yun; Liu Xinran; Biederer Thomas; Südhof Thomas C
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14464-9.
2002: Fernández-Chacón Rafael; Shin Ok-Ho; Königstorfer Andreas; Matos Maria F; Meyer Alexander C; Garcia Jesus; Gerber Stefan H; Rizo Josep; Südhof Thomas C; Rosenmund Christian
Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(19):8438-46.
2002: Schlüter Oliver M; Khvotchev Mikhail; Jahn Reinhard; Südhof Thomas C
Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion.
The Journal of biological chemistry 2002;277(43):40919-29.
2002: Biederer Thomas; Cao Xinwei; Südhof Thomas C; Liu Xinran
Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(17):7340-51.
2002: Riedel Dietmar; Antonin Wolfram; Fernandez-Chacon Rafael; Alvarez de Toledo Guillermo; Jo Tobias; Geppert Martin; Valentijn Jack A; Valentijn Karin; Jamieson James D; Südhof Thomas C; Jahn Reinhard
Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.
Molecular and cellular biology 2002;22(18):6487-97.
2002: Biederer Thomas; Sara Yildirim; Mozhayeva Marina; Atasoy Deniz; Liu Xinran; Kavalali Ege T; Südhof Thomas C
SynCAM, a synaptic adhesion molecule that drives synapse assembly.
Science (New York, N.Y.) 2002;297(5586):1525-31.
2002: Rizo Josep; Südhof Thomas C
Snares and Munc18 in synaptic vesicle fusion.
Nature reviews. Neuroscience 2002;3(8):641-53.
2002: Dulubova Irina; Yamaguchi Tomohiro; Gao Yan; Min Sang-Won; Huryeva Iryna; Südhof Thomas C; Rizo Josep
How Tlg2p/syntaxin 16 'snares' Vps45.
The EMBO journal 2002;21(14):3620-31.
2002: Shin Ok-Ho; Rizo Josep; Südhof Thomas C
Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells.
Nature neuroscience 2002;5(7):649-56.
2002: Tabuchi Katsuhiko; Südhof Thomas C
Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.
Genomics 2002;79(6):849-59.
2002: Lu Jun; Garcia Jesus; Dulubova Irina; Südhof Thomas C; Rizo Josep
Solution structure of the Vam7p PX domain.
Biochemistry 2002;41(19):5956-62.
2002: Yamaguchi Tomohiro; Dulubova Irina; Min Sang-Won; Chen Xiaocheng; Rizo Josep; Südhof Thomas C
Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif.
Developmental cell 2002;2(3):295-305.
2002: Südhof Thomas C
Synaptotagmins: why so many?
The Journal of biological chemistry 2002;277(10):7629-32.
2002: Sugita Shuzo; Shin Ok-Ho; Han Weiping; Lao Ye; Südhof Thomas C
Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities.
The EMBO journal 2002;21(3):270-80.
2002: Gerber Stefan H; Rizo Josep; Südhof Thomas C
Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I.
Diabetes 2002;51 Suppl 1():S12-8.
2002: Gerber Stefan H; Südhof Thomas C
Molecular determinants of regulated exocytosis.
Diabetes 2002;51 Suppl 1():S3-11.
2002: Tobaben Sönke; Südhof Thomas C; Stahl Bernd
Genetic analysis of alpha-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1 alpha.
The Journal of biological chemistry 2002;277(8):6359-65.
2002: Chen Xiaocheng; Tomchick Diana R; Kovrigin Evguenii; Araç Demet; Machius Mischa; Südhof Thomas C; Rizo Josep
Three-dimensional structure of the complexin/SNARE complex.
Neuron 2002;33(3):397-409.
2002: Castillo Pablo E; Schoch Susanne; Schmitz Frank; Südhof Thomas C; Malenka Robert C
RIM1alpha is required for presynaptic long-term potentiation.
Nature 2002;415(6869):327-30.
2002: Schoch Susanne; Castillo Pablo E; Jo Tobias; Mukherjee Konark; Geppert Martin; Wang Yun; Schmitz Frank; Malenka Robert C; Südhof Thomas C
RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.
Nature 2002;415(6869):321-6.
2002: Rhee Jeong Seop; Betz Andrea; Pyott Sonja; Reim Kerstin; Varoqueaux Frederique; Augustin Iris; Hesse Dörte; Südhof Thomas C; Takahashi Masami; Rosenmund Christian; Brose Nils
Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.
Cell 2002;108(1):121-33.
2002: Sugita S; Ho A; Südhof T C
NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern.
Neuroscience 2002;112(1):51-63.
2001: Fernandez I; Araç D; Ubach J; Gerber S H; Shin O; Gao Y; Anderson R G; Südhof T C; Rizo J
Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron 2001;32(6):1057-69.
2001: Schoch S; Deák F; Königstorfer A; Mozhayeva M; Sara Y; Südhof T C; Kavalali E T
SNARE function analyzed in synaptobrevin/VAMP knockout mice.
Science (New York, N.Y.) 2001;294(5544):1117-22.
2001: Lonart G; Südhof T C
Characterization of rabphilin phosphorylation using phospho-specific antibodies.
Neuropharmacology 2001;41(6):643-9.
2001: Tobaben S; Thakur P; Fernández-Chacón R; Südhof T C; Rettig J; Stahl B
A trimeric protein complex functions as a synaptic chaperone machine.
Neuron 2001;31(6):987-99.
2001: Voets T; Moser T; Lund P E; Chow R H; Geppert M; Südhof T C; Neher E
Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11680-5.
2001: Voets T; Toonen R F; Brian E C; de Wit H; Moser T; Rettig J; Südhof T C; Neher E; Verhage M
Munc18-1 promotes large dense-core vesicle docking.
Neuron 2001;31(4):581-91.
2001: Gerber S H; Rizo J; Südhof T C
The top loops of the C(2) domains from synaptotagmin and phospholipase A(2) control functional specificity.
The Journal of biological chemistry 2001;276(34):32288-92.
2001: Sugita S; Saito F; Tang J; Satz J; Campbell K; Südhof T C
A stoichiometric complex of neurexins and dystroglycan in brain.
The Journal of cell biology 2001;154(2):435-45.
2001: Cao X; Südhof T C
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60.
Science (New York, N.Y.) 2001;293(5527):115-20.
2001: Wang Y; Dulubova I; Rizo J; Südhof T C
Functional analysis of conserved structural elements in yeast syntaxin Vam3p.
The Journal of biological chemistry 2001;276(30):28598-605.
2001: Sugita S; Han W; Butz S; Liu X; Fernández-Chacón R; Lao Y; Südhof T C
Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis.
Neuron 2001;30(2):459-73.
2001: Ubach J; Lao Y; Fernandez I; Arac D; Südhof T C; Rizo J
The C2B domain of synaptotagmin I is a Ca2+-binding module.
Biochemistry 2001;40(20):5854-60.
2001: Gerber S H; Garcia J; Rizo J; Südhof T C
An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release.
The EMBO journal 2001;20(7):1605-19.
2001: Barylko B; Gerber S H; Binns D D; Grichine N; Khvotchev M; Südhof T C; Albanesi J P
A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans.
The Journal of biological chemistry 2001;276(11):7705-8.
2001: Fernández-Chacón R; Königstorfer A; Gerber S H; García J; Matos M F; Stevens C F; Brose N; Rizo J; Rosenmund C; Südhof T C
Synaptotagmin I functions as a calcium regulator of release probability.
Nature 2001;410(6824):41-9.
2001: Dulubova I; Yamaguchi T; Wang Y; Südhof T C; Rizo J
Vam3p structure reveals conserved and divergent properties of syntaxins.
Nature structural biology 2001;8(3):258-64.
2001: von Poser C; Südhof T C
Synaptotagmin 13: structure and expression of a novel synaptotagmin.
European journal of cell biology 2001;80(1):41-7.
2001: Reim K; Mansour M; Varoqueaux F; McMahon H T; Südhof T C; Brose N; Rosenmund C
Complexins regulate a late step in Ca2+-dependent neurotransmitter release.
Cell 2001;104(1):71-81.
2001: Augustin I; Korte S; Rickmann M; Kretzschmar H A; Südhof T C; Herms J W; Brose N
The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):10-7.
2001: Honarpour N; Tabuchi K; Stark J M; Hammer R E; Südhof T C; Parada L F; Wang X; Richardson J A; Herz J
Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1.
Neuroscience 2001;106(2):263-74.
2001: Südhof T C
alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.
Annual review of neuroscience 2001;24():933-62.
2000: Schmitz F; Königstorfer A; Südhof T C
RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function.
Neuron 2000;28(3):857-72.
2000: Biederer T; Südhof T C
Mints as adaptors. Direct binding to neurexins and recruitment of munc18.
The Journal of biological chemistry 2000;275(51):39803-6.
2000: Fernández-Chacón R; Südhof T C
Novel SCAMPs lacking NPF repeats: ubiquitous and synaptic vesicle-specific forms implicate SCAMPs in multiple membrane-trafficking functions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):7941-50.
2000: Tobaben S; Südhof T C; Stahl B
The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.
The Journal of biological chemistry 2000;275(46):36204-10.
2000: Lonart G; Südhof T C
Assembly of SNARE core complexes prior to neurotransmitter release sets the readily releasable pool of synaptic vesicles.
The Journal of biological chemistry 2000;275(36):27703-7.
2000: Zhang W; Li J L; Hosaka M; Janz R; Shelton J M; Albright G M; Richardson J A; Südhof T C; Victor R G
Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9765-70.
2000: Khvotchev M; Südhof T C
alpha-latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membrane.
The EMBO journal 2000;19(13):3250-62.
2000: Matos M F; Rizo J; Südhof T C
The relation of protein binding to function: what is the significance of munc18 and synaptotagmin binding to syntaxin 1, and where are the corresponding binding sites?
European journal of cell biology 2000;79(6):377-82.
2000: Pabst S; Hazzard J W; Antonin W; Südhof T C; Jahn R; Rizo J; Fasshauer D
Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions.
The Journal of biological chemistry 2000;275(26):19808-18.
2000: Fernández-Chacón R; Achiriloaie M; Janz R; Albanesi J P; Südhof T C
SCAMP1 function in endocytosis.
The Journal of biological chemistry 2000;275(17):12752-6.
2000: Sugita S; Südhof T C
Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins.
Biochemistry 2000;39(11):2940-9.
2000: Verhage M; Maia A S; Plomp J J; Brussaard A B; Heeroma J H; Vermeer H; Toonen R F; Hammer R E; van den Berg T K; Missler M; Geuze H J; Südhof T C
Synaptic assembly of the brain in the absence of neurotransmitter secretion.
Science (New York, N.Y.) 2000;287(5454):864-9.
2000: Tsigelny I; Shindyalov I N; Bourne P E; Südhof T C; Taylor P
Common EF-hand motifs in cholinesterases and neuroligins suggest a role for Ca2+ binding in cell surface associations.
Protein science : a publication of the Protein Society 2000;9(1):180-5.
2000: Khvotchev M; Lonart G; Südhof T C
Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose.
Neuroscience 2000;101(3):793-802.
1999: Janz R; Goda Y; Geppert M; Missler M; Südhof T C
SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.
Neuron 1999;24(4):1003-16.
1999: Janz R; Südhof T C; Hammer R E; Unni V; Siegelbaum S A; Bolshakov V Y
Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I.
Neuron 1999;24(3):687-700.
1999: Fernández-Chacón R; Alvarez de Toledo G; Hammer R E; Südhof T C
Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice.
The Journal of biological chemistry 1999;274(46):32551-4.
1999: Hosaka M; Hammer R E; Südhof T C
A phospho-switch controls the dynamic association of synapsins with synaptic vesicles.
Neuron 1999;24(2):377-87.
1999: Rudenko G; Nguyen T; Chelliah Y; Südhof T C; Deisenhofer J
The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing.
Cell 1999;99(1):93-101.
1999: Maximov A; Südhof T C; Bezprozvanny I
Association of neuronal calcium channels with modular adaptor proteins.
The Journal of biological chemistry 1999;274(35):24453-6.
1999: Dulubova I; Sugita S; Hill S; Hosaka M; Fernandez I; Südhof T C; Rizo J
A conformational switch in syntaxin during exocytosis: role of munc18.
The EMBO journal 1999;18(16):4372-82.
1999: Hazzard J; Südhof T C; Rizo J
NMR analysis of the structure of synaptobrevin and of its interaction with syntaxin.
Journal of biomolecular NMR 1999;14(3):203-7.
1999: Augustin I; Rosenmund C; Südhof T C; Brose N
Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.
Nature 1999;400(6743):457-61.
1999: Schlüter O M; Schnell E; Verhage M; Tzonopoulos T; Nicoll R A; Janz R; Malenka R C; Geppert M; Südhof T C
Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(14):5834-46.
1999: Sugita S; Janz R; Südhof T C
Synaptogyrins regulate Ca2+-dependent exocytosis in PC12 cells.
The Journal of biological chemistry 1999;274(27):18893-901.
1999: Ubach J; García J; Nittler M P; Südhof T C; Rizo J
Structure of the Janus-faced C2B domain of rabphilin.
Nature cell biology 1999;1(2):106-12.
1999: Stahl B; Tobaben S; Südhof T C
Two distinct domains in hsc70 are essential for the interaction with the synaptic vesicle cysteine string protein.
European journal of cell biology 1999;78(6):375-81.
1999: Okamoto M; Schoch S; Südhof T C
EHSH1/intersectin, a protein that contains EH and SH3 domains and binds to dynamin and SNAP-25. A protein connection between exocytosis and endocytosis?
The Journal of biological chemistry 1999;274(26):18446-54.
1999: Butz S; Fernandez-Chacon R; Schmitz F; Jahn R; Südhof T C
The subcellular localizations of atypical synaptotagmins III and VI. Synaptotagmin III is enriched in synapses and synaptic plasma membranes but not in synaptic vesicles.
The Journal of biological chemistry 1999;274(26):18290-6.
1999: Hosaka M; Südhof T C
Homo- and heterodimerization of synapsins.
The Journal of biological chemistry 1999;274(24):16747-53.
1999: Stahl B; Diehlmann A; Südhof T C
Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071.
The Journal of biological chemistry 1999;274(14):9141-8.
1999: Sugita S; Khvochtev M; Südhof T C
Neurexins are functional alpha-latrotoxin receptors.
Neuron 1999;22(3):489-96.
1999: Song J Y; Ichtchenko K; Südhof T C; Brose N
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):1100-5.
1999: Janz R; Südhof T C
SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family.
Neuroscience 1999;94(4):1279-90.
1999: Fernández-Chacón R; Südhof T C
Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle.
Annual review of physiology 1999;61():753-76.
1998: Missler M; Hammer R E; Südhof T C
Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.
The Journal of biological chemistry 1998;273(52):34716-23.
1998: Sugita S; Ichtchenko K; Khvotchev M; Südhof T C
alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.
The Journal of biological chemistry 1998;273(49):32715-24.
1998: Okamoto M; Südhof T C
Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2.
European journal of cell biology 1998;77(3):161-5.
1998: Lonart G; Janz R; Johnson K M; Südhof T C
Mechanism of action of rab3A in mossy fiber LTP.
Neuron 1998;21(5):1141-50.
1998: Shao X; Fernandez I; Südhof T C; Rizo J
Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?
Biochemistry 1998;37(46):16106-15.
1998: Janz R; Hofmann K; Südhof T C
SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(22):9269-81.
1998: Ichtchenko K; Khvotchev M; Kiyatkin N; Simpson L; Sugita S; Südhof T C
alpha-latrotoxin action probed with recombinant toxin: receptors recruit alpha-latrotoxin but do not transduce an exocytotic signal.
The EMBO journal 1998;17(21):6188-99.
1998: Missler M; Fernandez-Chacon R; Südhof T C
The making of neurexins.
Journal of neurochemistry 1998;71(4):1339-47.
1998: Fernandez I; Ubach J; Dulubova I; Zhang X; Südhof T C; Rizo J
Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell 1998;94(6):841-9.
1998: Butz S; Okamoto M; Südhof T C
A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
Cell 1998;94(6):773-82.
1998: Zhang X; Rizo J; Südhof T C
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I.
Biochemistry 1998;37(36):12395-403.
1998: Khvotchev M; Südhof T C
Newly synthesized phosphatidylinositol phosphates are required for synaptic norepinephrine but not glutamate or gamma-aminobutyric acid (GABA) release.
The Journal of biological chemistry 1998;273(34):21451-4.
1998: Betz A; Ashery U; Rickmann M; Augustin I; Neher E; Südhof T C; Rettig J; Brose N
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
Neuron 1998;21(1):123-36.
1998: Ubach J; Zhang X; Shao X; Südhof T C; Rizo J
Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?
The EMBO journal 1998;17(14):3921-30.
1998: Rizo J; Südhof T C
C2-domains, structure and function of a universal Ca2+-binding domain.
The Journal of biological chemistry 1998;273(26):15879-82.
1998: Hosaka M; Südhof T C
Synapsin III, a novel synapsin with an unusual regulation by Ca2+.
The Journal of biological chemistry 1998;273(22):13371-4.
1998: Esser L; Wang C R; Hosaka M; Smagula C S; Südhof T C; Deisenhofer J
Synapsin I is structurally similar to ATP-utilizing enzymes.
The EMBO journal 1998;17(4):977-84.
1998: Missler M; Südhof T C
Neurexins: three genes and 1001 products.
Trends in genetics : TIG 1998;14(1):20-6.
1998: Janz R; Südhof T C
Cellugyrin, a novel ubiquitous form of synaptogyrin that is phosphorylated by pp60c-src.
The Journal of biological chemistry 1998;273(5):2851-7.
1998: Khvotchev M; Südhof T C
Developmentally regulated alternative splicing in a novel synaptojanin.
The Journal of biological chemistry 1998;273(4):2306-11.
1998: Geppert M; Khvotchev M; Krasnoperov V; Goda Y; Missler M; Hammer R E; Ichtchenko K; Petrenko A G; Südhof T C
Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.
The Journal of biological chemistry 1998;273(3):1705-10.
1998: Hosaka M; Südhof T C
Synapsins I and II are ATP-binding proteins with differential Ca2+ regulation.
The Journal of biological chemistry 1998;273(3):1425-9.
1998: Lonart G; Südhof T C
Region-specific phosphorylation of rabphilin in mossy fiber nerve terminals of the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(2):634-40.
1998: Geppert M; Südhof T C
RAB3 and synaptotagmin: the yin and yang of synaptic membrane fusion.
Annual review of neuroscience 1998;21():75-95.
1997: Shao X; Südhof T C; Rizo J
Assignment of the 1H, 15N and 13C resonances of the calcium-free and calcium-bound forms of the first C2-domain of synaptotagmin I.
Journal of biomolecular NMR 1997;10(3):307-8.
1997: Telemenakis I; Benseler F; Stenius K; Südhof T C; Brose N
Rat homologues of yeast sec7p.
European journal of cell biology 1997;74(2):143-9.
1997: Wang C R; Esser L; Smagula C S; Südhof T C; Deisenhofer J
Identification, expression, and crystallization of the protease-resistant conserved domain of synapsin I.
Protein science : a publication of the Protein Society 1997;6(10):2264-7.
1997: Nguyen T; Südhof T C
Binding properties of neuroligin 1 and neurexin 1beta reveal function as heterophilic cell adhesion molecules.
The Journal of biological chemistry 1997;272(41):26032-9.
1997: Goda Y; Südhof T C
Calcium regulation of neurotransmitter release: reliably unreliable?
Current opinion in cell biology 1997;9(4):513-8.
1997: Wang Y; Okamoto M; Schmitz F; Hofmann K; Südhof T C
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion.
Nature 1997;388(6642):593-8.
1997: Geppert M; Goda Y; Stevens C F; Südhof T C
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion.
Nature 1997;387(6635):810-4.
1997: von Poser C; Ichtchenko K; Shao X; Rizo J; Südhof T C
The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding.
The Journal of biological chemistry 1997;272(22):14314-9.
1997: Verhage M; de Vries K J; Røshol H; Burbach J P; Gispen W H; Südhof T C
DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion.
Neuron 1997;18(3):453-61.
1997: Shao X; Li C; Fernandez I; Zhang X; Südhof T C; Rizo J
Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch.
Neuron 1997;18(1):133-42.
1996: Südhof T C; Rizo J
Synaptotagmins: C2-domain proteins that regulate membrane traffic.
Neuron 1996;17(3):379-88.
1996: Chapman E R; Blasi J; An S; Brose N; Johnston P A; Südhof T C; Jahn R
Fatty acylation of synaptotagmin in PC12 cells and synaptosomes.
Biochemical and biophysical research communications 1996;225(1):326-32.
1996: Petrenko A G; Ullrich B; Missler M; Krasnoperov V; Rosahl T W; Südhof T C
Structure and evolution of neurexophilin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(14):4360-9.
1996: Shao X; Davletov B A; Sutton R B; Südhof T C; Rizo J
Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C.
Science (New York, N.Y.) 1996;273(5272):248-51.
1996: McMahon H T; Bolshakov V Y; Janz R; Hammer R E; Siegelbaum S A; Südhof T C
Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4760-4.
1996: Hata Y; Butz S; Südhof T C
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(8):2488-94.
1996: Stahl B; Chou J H; Li C; Südhof T C; Jahn R
Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras.
The EMBO journal 1996;15(8):1799-809.
1996: Ichtchenko K; Nguyen T; Südhof T C
Structures, alternative splicing, and neurexin binding of multiple neuroligins.
The Journal of biological chemistry 1996;271(5):2676-82.
1996: Sugita S; Hata Y; Südhof T C
Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I.
The Journal of biological chemistry 1996;271(3):1262-5.
1995: Stenius K; Janz R; Südhof T C; Jahn R
Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.
The Journal of cell biology 1995;131(6 Pt 2):1801-9.
1995: Spillane D M; Rosahl T W; Südhof T C; Malenka R C
Long-term potentiation in mice lacking synapsins.
Neuropharmacology 1995;34(11):1573-9.
1995: Ullrich B; Südhof T C
Differential distributions of novel synaptotagmins: comparison to synapsins.
Neuropharmacology 1995;34(11):1371-7.
1995: Davletov B A; Krasnoperov V; Hata Y; Petrenko A G; Südhof T C
High affinity binding of alpha-latrotoxin to recombinant neurexin I alpha.
The Journal of biological chemistry 1995;270(41):23903-5.
1995: Brose N; Hofmann K; Hata Y; Südhof T C
Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins.
The Journal of biological chemistry 1995;270(42):25273-80.
1995: Li C; Davletov B A; Südhof T C
Distinct Ca2+ and Sr2+ binding properties of synaptotagmins. Definition of candidate Ca2+ sensors for the fast and slow components of neurotransmitter release.
The Journal of biological chemistry 1995;270(42):24898-902.
1995: McMahon H T; Missler M; Li C; Südhof T C
Complexins: cytosolic proteins that regulate SNAP receptor function.
Cell 1995;83(1):111-9.
1995: Südhof T C
The synaptic vesicle cycle: a cascade of protein-protein interactions.
Nature 1995;375(6533):645-53.
1995: Li C; Ullrich B; Zhang J Z; Anderson R G; Brose N; Südhof T C
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.
Nature 1995;375(6532):594-9.
1995: Rosahl T W; Spillane D; Missler M; Herz J; Selig D K; Wolff J R; Hammer R E; Malenka R C; Südhof T C
Essential functions of synapsins I and II in synaptic vesicle regulation.
Nature 1995;375(6531):488-93.
1995: Hata Y; Südhof T C
A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic.
The Journal of biological chemistry 1995;270(22):13022-8.
1995: Ichtchenko K; Hata Y; Nguyen T; Ullrich B; Missler M; Moomaw C; Südhof T C
Neuroligin 1: a splice site-specific ligand for beta-neurexins.
Cell 1995;81(3):435-43.
1995: Wang L H; Südhof T C; Anderson R G
The appendage domain of alpha-adaptin is a high affinity binding site for dynamin.
The Journal of biological chemistry 1995;270(17):10079-83.
1995: Fykse E M; Li C; Südhof T C
Phosphorylation of rabphilin-3A by Ca2+/calmodulin- and cAMP-dependent protein kinases in vitro.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(3 Pt 2):2385-95.
1995: Sutton R B; Davletov B A; Berghuis A M; Südhof T C; Sprang S R
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.
Cell 1995;80(6):929-38.
1995: Ullrich B; Ushkaryov Y A; Südhof T C
Cartography of neurexins: more than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons.
Neuron 1995;14(3):497-507.
1995: McMahon H T; Südhof T C
Synaptic core complex of synaptobrevin, syntaxin, and SNAP25 forms high affinity alpha-SNAP binding site.
The Journal of biological chemistry 1995;270(5):2213-7.
1995: Janz R; Südhof T C
A systematic approach to studying synaptic function in vertebrates.
Cold Spring Harbor symposia on quantitative biology 1995;60():309-14.
1995: Li X; Rosahl T W; Südhof T C; Francke U
Mapping of synapsin II (SYN2) genes to human chromosome 3p and mouse chromosome 6 band F.
Cytogenetics and cell genetics 1995;71(3):301-5.
1994: Ullrich B; Li C; Zhang J Z; McMahon H; Anderson R G; Geppert M; Südhof T C
Functional properties of multiple synaptotagmins in brain.
Neuron 1994;13(6):1281-91.
1994: Fischer von Mollard G; Stahl B; Walch-Solimena C; Takei K; Daniels L; Khoklatchev A; De Camilli P; Südhof T C; Jahn R
Localization of Rab5 to synaptic vesicles identifies endosomal intermediate in synaptic vesicle recycling pathway.
European journal of cell biology 1994;65(2):319-26.
1994: Newton C L; Mignery G A; Südhof T C
Co-expression in vertebrate tissues and cell lines of multiple inositol 1,4,5-trisphosphate (InsP3) receptors with distinct affinities for InsP3.
The Journal of biological chemistry 1994;269(46):28613-9.
1994: Davletov B A; Südhof T C
Ca(2+)-dependent conformational change in synaptotagmin I.
The Journal of biological chemistry 1994;269(46):28547-50.
1994: Hayashi T; McMahon H; Yamasaki S; Binz T; Hata Y; Südhof T C; Niemann H
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.
The EMBO journal 1994;13(21):5051-61.
1994: Geppert M; Goda Y; Hammer R E; Li C; Rosahl T W; Stevens C F; Südhof T C
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse.
Cell 1994;79(4):717-27.
1994: Li C; Takei K; Geppert M; Daniell L; Stenius K; Chapman E R; Jahn R; De Camilli P; Südhof T C
Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C.
Neuron 1994;13(4):885-98.
1994: Zhang J Z; Davletov B A; Südhof T C; Anderson R G
Synaptotagmin I is a high affinity receptor for clathrin AP-2: implications for membrane recycling.
Cell 1994;78(5):751-60.
1994: Geppert M; Ullrich B; Green D G; Takei K; Daniels L; De Camilli P; Südhof T C; Hammer R E
Synaptic targeting domains of synapsin I revealed by transgenic expression in photoreceptor cells.
The EMBO journal 1994;13(16):3720-7.
1994: Liu J P; Powell K A; Südhof T C; Robinson P J
Dynamin I is a Ca(2+)-sensitive phospholipid-binding protein with very high affinity for protein kinase C.
The Journal of biological chemistry 1994;269(33):21043-50.
1994: Robinson P J; Liu J P; Powell K A; Fykse E M; Südhof T C
Phosphorylation of dynamin I and synaptic-vesicle recycling.
Trends in neurosciences 1994;17(8):348-53.
1994: Reizes O; Barylko B; Li C; Südhof T C; Albanesi J P
Domain structure of a mammalian myosin I beta.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6349-53.
1994: Geppert M; Bolshakov V Y; Siegelbaum S A; Takei K; De Camilli P; Hammer R E; Südhof T C
The role of Rab3A in neurotransmitter release.
Nature 1994;369(6480):493-7.
1994: Yamasaki S; Baumeister A; Binz T; Blasi J; Link E; Cornille F; Roques B; Fykse E M; Südhof T C; Jahn R
Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin.
The Journal of biological chemistry 1994;269(17):12764-72.
1994: Ushkaryov Y A; Hata Y; Ichtchenko K; Moomaw C; Afendis S; Slaughter C A; Südhof T C
Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.
The Journal of biological chemistry 1994;269(16):11987-92.
1994: Fischer von Mollard G; Stahl B; Khokhlatchev A; Südhof T C; Jahn R
Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis.
The Journal of biological chemistry 1994;269(15):10971-4.
1994: Fischer von Mollard G; Stahl B; Li C; Südhof T C; Jahn R
Rab proteins in regulated exocytosis.
Trends in biochemical sciences 1994;19(4):164-8.
1994: Sontag J M; Fykse E M; Ushkaryov Y; Liu J P; Robinson P J; Südhof T C
Differential expression and regulation of multiple dynamins.
The Journal of biological chemistry 1994;269(6):4547-54.
1994: Takei K; Mignery G A; Mugnaini E; Südhof T C; De Camilli P
Inositol 1,4,5-trisphosphate receptor causes formation of ER cisternal stacks in transfected fibroblasts and in cerebellar Purkinje cells.
Neuron 1994;12(2):327-42.
1994: Binz T; Blasi J; Yamasaki S; Baumeister A; Link E; Südhof T C; Jahn R; Niemann H
Proteolysis of SNAP-25 by types E and A botulinal neurotoxins.
The Journal of biological chemistry 1994;269(3):1617-20.
1994: Jahn R; Südhof T C
Synaptic vesicles and exocytosis.
Annual review of neuroscience 1994;17():219-46.
1994: Ullrich B; Südhof T C
Distribution of synaptic markers in the retina: implications for synaptic vesicle traffic in ribbon synapses.
Journal of physiology, Paris 1994;88(4):249-57.
1993: Davletov B A; Südhof T C
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
The Journal of biological chemistry 1993;268(35):26386-90.
1993: Hata Y; Slaughter C A; Südhof T C
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin.
Nature 1993;366(6453):347-51.
1993: Fykse E M; Takei K; Walch-Solimena C; Geppert M; Jahn R; De Camilli P; Südhof T C
Relative properties and localizations of synaptic vesicle protein isoforms: the case of the synaptophysins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(11):4997-5007.
1993: Rosahl T W; Geppert M; Spillane D; Herz J; Hammer R E; Malenka R C; Südhof T C
Short-term synaptic plasticity is altered in mice lacking synapsin I.
Cell 1993;75(4):661-70.
1993: Südhof T C; De Camilli P; Niemann H; Jahn R
Membrane fusion machinery: insights from synaptic proteins.
Cell 1993;75(1):1-4.
1993: Robinson P J; Sontag J M; Liu J P; Fykse E M; Slaughter C; McMahon H; Südhof T C
Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals.
Nature 1993;365(6442):163-6.
1993: Walch-Solimena C; Takei K; Marek K L; Midyett K; Südhof T C; De Camilli P; Jahn R
Synaptotagmin: a membrane constituent of neuropeptide-containing large dense-core vesicles.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(9):3895-903.
1993: Link E; McMahon H; Fischer von Mollard G; Yamasaki S; Niemann H; Südhof T C; Jahn R
Cleavage of cellubrevin by tetanus toxin does not affect fusion of early endosomes.
The Journal of biological chemistry 1993;268(25):18423-6.
1993: Blasi J; Chapman E R; Link E; Binz T; Yamasaki S; De Camilli P; Südhof T C; Niemann H; Jahn R
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25.
Nature 1993;365(6442):160-3.
1993: Jahn R; Südhof T C
Synaptic vesicle traffic: rush hour in the nerve terminal.
Journal of neurochemistry 1993;61(1):12-21.
1993: Ushkaryov Y A; Südhof T C
Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6410-4.
1993: McMahon H T; Ushkaryov Y A; Edelmann L; Link E; Binz T; Niemann H; Jahn R; Südhof T C
Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein.
Nature 1993;364(6435):346-9.
1993: Baumert M; Fischer von Mollard G; Jahn R; Südhof T C
Structure of the murine rab3A gene: correlation of genomic organization with antibody epitopes.
The Biochemical journal 1993;293 ( Pt 1)():157-63.
1993: Armstrong S A; Seabra M C; Südhof T C; Goldstein J L; Brown M S
cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase.
The Journal of biological chemistry 1993;268(16):12221-9.
1993: Walch-Solimena C; Jahn R; Südhof T C
Synaptic vesicle proteins in exocytosis: what do we know?
Current opinion in neurobiology 1993;3(3):329-36.
1993: Davletov B; Sontag J M; Hata Y; Petrenko A G; Fykse E M; Jahn R; Südhof T C
Phosphorylation of synaptotagmin I by casein kinase II.
The Journal of biological chemistry 1993;268(9):6816-22.
1993: Hata Y; Davletov B; Petrenko A G; Jahn R; Südhof T C
Interaction of synaptotagmin with the cytoplasmic domains of neurexins.
Neuron 1993;10(2):307-15.
1993: Petrenko A G; Lazaryeva V D; Geppert M; Tarasyuk T A; Moomaw C; Khokhlatchev A V; Ushkaryov Y A; Slaughter C; Nasimov I V; Südhof T C
Polypeptide composition of the alpha-latrotoxin receptor. High affinity binding protein consists of a family of related high molecular weight polypeptides complexed to a low molecular weight protein.
The Journal of biological chemistry 1993;268(3):1860-7.
1993: Südhof T C; Petrenko A G; Whittaker V P; Jahn R
Molecular approaches to synaptic vesicle exocytosis.
Progress in brain research 1993;98():235-40.
1992: Link E; Edelmann L; Chou J H; Binz T; Yamasaki S; Eisel U; Baumert M; Südhof T C; Niemann H; Jahn R
Tetanus toxin action: inhibition of neurotransmitter release linked to synaptobrevin proteolysis.
Biochemical and biophysical research communications 1992;189(2):1017-23.
1992: Seabra M C; Brown M S; Slaughter C A; Südhof T C; Goldstein J L
Purification of component A of Rab geranylgeranyl transferase: possible identity with the choroideremia gene product.
Cell 1992;70(6):1049-57.
1992: Ushkaryov Y A; Petrenko A G; Geppert M; Südhof T C
Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.
Science (New York, N.Y.) 1992;257(5066):50-6.
1992: Lin H C; Südhof T C; Anderson R G
Annexin VI is required for budding of clathrin-coated pits.
Cell 1992;70(2):283-91.
1992: Seabra M C; Goldstein J L; Südhof T C; Brown M S
Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys.
The Journal of biological chemistry 1992;267(20):14497-503.
1992: Matteoli M; Takei K; Perin M S; Südhof T C; De Camilli P
Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons.
The Journal of cell biology 1992;117(4):849-61.
1992: Mignery G A; Johnston P A; Südhof T C
Mechanism of Ca2+ inhibition of inositol 1,4,5-trisphosphate (InsP3) binding to the cerebellar InsP3 receptor.
The Journal of biological chemistry 1992;267(11):7450-5.
1992: Takei K; Stukenbrok H; Metcalf A; Mignery G A; Südhof T C; Volpe P; De Camilli P
Ca2+ stores in Purkinje neurons: endoplasmic reticulum subcompartments demonstrated by the heterogeneous distribution of the InsP3 receptor, Ca(2+)-ATPase, and calsequestrin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(2):489-505.
1992: Geppert M; Ushkaryov Y A; Hata Y; Davletov B; Petrenko A G; Südhof T C
Neurexins.
Cold Spring Harbor symposia on quantitative biology 1992;57():483-90.
1991: Matteoli M; Takei K; Cameron R; Hurlbut P; Johnston P A; Südhof T C; Jahn R; De Camilli P
Association of Rab3A with synaptic vesicles at late stages of the secretory pathway.
The Journal of cell biology 1991;115(3):625-33.
1991: Südhof T C; Newton C L; Archer B T; Ushkaryov Y A; Mignery G A
Structure of a novel InsP3 receptor.
The EMBO journal 1991;10(11):3199-206.
1991: Cameron P L; Südhof T C; Jahn R; De Camilli P
Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.
The Journal of cell biology 1991;115(1):151-64.
1991: Petrenko A G; Perin M S; Davletov B A; Ushkaryov Y A; Geppert M; Südhof T C
Binding of synaptotagmin to the alpha-latrotoxin receptor implicates both in synaptic vesicle exocytosis.
Nature 1991;353(6339):65-8.
1991: Geppert M; Archer B T; Südhof T C
Synaptotagmin II. A novel differentially distributed form of synaptotagmin.
The Journal of biological chemistry 1991;266(21):13548-52.
1991: Johnston P A; Archer B T; Robinson K; Mignery G A; Jahn R; Südhof T C
rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence.
Neuron 1991;7(1):101-9.
1991: Südhof T C; Jahn R
Proteins of synaptic vesicles involved in exocytosis and membrane recycling.
Neuron 1991;6(5):665-77.
1991: Perin M S; Fried V A; Stone D K; Xie X S; Südhof T C
Structure of the 116-kDa polypeptide of the clathrin-coated vesicle/synaptic vesicle proton pump.
The Journal of biological chemistry 1991;266(6):3877-81.
1991: Perin M S; Brose N; Jahn R; Südhof T C
Domain structure of synaptotagmin (p65)
The Journal of biological chemistry 1991;266(1):623-9.
1991: Perin M S; Johnston P A; Ozcelik T; Jahn R; Francke U; Südhof T C
Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans.
The Journal of biological chemistry 1991;266(1):615-22.
1990: Yu F X; Johnston P A; Südhof T C; Yin H L
gCap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein.
Science (New York, N.Y.) 1990;250(4986):1413-5.
1990: Mignery G A; Südhof T C
The ligand binding site and transduction mechanism in the inositol-1,4,5-triphosphate receptor.
The EMBO journal 1990;9(12):3893-8.
1990: Johnston P A; Südhof T C
Evolutionary conservation and structural determinants of the calelectrins (annexins).
Biochemical Society transactions 1990;18(6):1097-8.
1990: Johnston P A; Yu F X; Reynolds G A; Yin H L; Moomaw C R; Slaughter C A; Südhof T C
Purification and expression of gCap39. An intracellular and secreted Ca2(+)-dependent actin-binding protein enriched in mononuclear phagocytes.
The Journal of biological chemistry 1990;265(29):17946-52.
1990: Archer B T; Ozçelik T; Jahn R; Francke U; Südhof T C
Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.
The Journal of biological chemistry 1990;265(28):17267-73.
1990: Ozçelik T; Lafreniere R G; Archer B T; Johnston P A; Willard H F; Francke U; Südhof T C
Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse.
American journal of human genetics 1990;47(3):551-61.
1990: Mignery G A; Newton C L; Archer B T; Südhof T C
Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.
The Journal of biological chemistry 1990;265(21):12679-85.
1990: Johnston P A; Perin M S; Reynolds G A; Wasserman S A; Südhof T C
Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development.
The Journal of biological chemistry 1990;265(19):11382-8.
1990: Perin M S; Fried V A; Mignery G A; Jahn R; Südhof T C
Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C.
Nature 1990;345(6272):260-3.
1990: Johnston P A; Südhof T C
The multisubunit structure of synaptophysin. Relationship between disulfide bonding and homo-oligomerization.
The Journal of biological chemistry 1990;265(15):8869-73.
1990: Südhof T C
The structure of the human synapsin I gene and protein.
The Journal of biological chemistry 1990;265(14):7849-52.
1990: Fischer von Mollard G; Mignery G A; Baumert M; Perin M S; Hanson T J; Burger P M; Jahn R; Südhof T C
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1988-92.
1989: Mignery G A; Südhof T C; Takei K; De Camilli P
Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor.
Nature 1989;342(6246):192-5.
1989: Stone D K; Crider B P; Südhof T C; Xie X S
Vacuolar proton pumps.
Journal of bioenergetics and biomembranes 1989;21(5):605-20.
1989: Südhof T C; Czernik A J; Kao H T; Takei K; Johnston P A; Horiuchi A; Kanazir S D; Wagner M A; Perin M S; De Camilli P
Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins.
Science (New York, N.Y.) 1989;245(4925):1474-80.
1989: Südhof T C
Synaptic vesicles.
Current opinion in cell biology 1989;1(4):655-9.
1989: Südhof T C; Fried V A; Stone D K; Johnston P A; Xie X S
Human endomembrane H+ pump strongly resembles the ATP-synthetase of Archaebacteria.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6067-71.
1989: Südhof T C; Baumert M; Perin M S; Jahn R
A synaptic vesicle membrane protein is conserved from mammals to Drosophila.
Neuron 1989;2(5):1475-81.
1989: Johnston P A; Jahn R; Südhof T C
Transmembrane topography and evolutionary conservation of synaptophysin.
The Journal of biological chemistry 1989;264(2):1268-73.
1988: Perin M S; Fried V A; Slaughter C A; Südhof T C
The structure of cytochrome b561, a secretory vesicle-specific electron transport protein.
The EMBO journal 1988;7(9):2697-703.
1988: Dawson P A; Hofmann S L; van der Westhuyzen D R; Südhof T C; Brown M S; Goldstein J L
Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1.
The Journal of biological chemistry 1988;263(7):3372-9.
1988: Südhof T C; Slaughter C A; Leznicki I; Barjon P; Reynolds G A
Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(3):664-8.
1987: van Driel I R; Goldstein J L; Südhof T C; Brown M S
First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins.
The Journal of biological chemistry 1987;262(36):17443-9.
1987: Südhof T C; Lottspeich F; Greengard P; Mehl E; Jahn R
A synaptic vesicle protein with a novel cytoplasmic domain and four transmembrane regions.
Science (New York, N.Y.) 1987;238(4830):1142-4.
1987: Südhof T C; Lottspeich F; Greengard P; Mehl E; Jahn R
The cDNA and derived amino acid sequences for rat and human synaptophysin.
Nucleic acids research 1987;15(22):9607.

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