FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Mitsuru Sugawara

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Physiology

Concepts & Ideas

Procedures

High Pressure Liquid Chromatography

Co-author Network

Publications

TOP 3
Hitoshi Kashiwagi; Kojiro Yamazaki; Yoh Takekuma; Vadivel Ganapathy; Mitsuru Sugawara
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Takashi Yamamoto; Kenichi Kuniki; Yoh Takekuma; Takeshi Hirano; Ken Iseki; Mitsuru Sugawara
Ribavirin uptake by cultured human choriocarcinoma (BeWo) cells and Xenopus laevis oocytes expressing recombinant plasma membrane human nucleoside transporters.
Mitsuru Sugawara; Shota Kadomura; Xin He; Yoh Takekuma; Naonori Kohri; Katsumi Miyazaki
The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Mitsuru Sugawara (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2009: Hitoshi Kashiwagi; Kojiro Yamazaki; Yoh Takekuma; Vadivel Ganapathy; Mitsuru Sugawara
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Amino acids 2009;36(2):219-30.
2007: Takashi Yamamoto; Kenichi Kuniki; Yoh Takekuma; Takeshi Hirano; Ken Iseki; Mitsuru Sugawara
Ribavirin uptake by cultured human choriocarcinoma (BeWo) cells and Xenopus laevis oocytes expressing recombinant plasma membrane human nucleoside transporters.
European journal of pharmacology 2007;557(1):1-8.
2005: Mitsuru Sugawara; Shota Kadomura; Xin He; Yoh Takekuma; Naonori Kohri; Katsumi Miyazaki
The use of an in vitro dissolution and absorption system to evaluate oral absorption of two weak bases in pH-independent controlled-release formulations.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;26(1):1-8.
2005: Mitsuru Sugawara; Takahiro Mochizuki; Yoh Takekuma; Katsumi Miyazaki
Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites.
Biochimica et biophysica acta 2005;1714(2):85-92.
2004: Xin He; Mitsuru Sugawara; Yoh Takekuma; Katsumi Miyazaki
Absorption of ester prodrugs in Caco-2 and rat intestine models.
Antimicrobial agents and chemotherapy 2004;48(7):2604-9.
2004: Satoshi Kishino; Maki Ogawa; Yoh Takekuma; Mitsuru Sugawara; Tsuyoshi Shimamura; Hiroyuki Furukawa; Satoru Todo; Katsumi Miyazaki
The variability of liver graft function and urinary 6beta-hydroxycortisol to cortisol ratio during liver regeneration in liver transplant recipients.
Clinical transplantation 2004;18(2):124-9.
2004: Xin He; Shota Kadomura; Yoh Takekuma; Mitsuru Sugawara; Katsumi Miyazaki
A new system for the prediction of drug absorption using a pH-controlled Caco-2 model: evaluation of pH-dependent soluble drug absorption and pH-related changes in absorption.
Journal of pharmaceutical sciences 2004;93(1):71-7.
2003: Tsutomu Nakagawa; Satoshi Kishino; Shin Itoh; Mitsuru Sugawara; Katsumi Miyazaki
Differential binding of disopyramide and warfarin enantiomers to human alpha(1)-acid glycoprotein variants.
British journal of clinical pharmacology 2003;56(6):664-9.
2003: Satoshi Kishino; Yoh Takekuma; Mitsuru Sugawara; Tsuyoshi Shimamura; Hiroyuki Furukawa; Satoru Todo; Katsumi Miyazaki
Influence of continuous venovenous haemodiafiltration on the pharmacokinetics of tacrolimus in liver transplant recipients with small-for-size grafts.
Clinical transplantation 2003;17(5):412-6.
2003: Xin He; Mitsuru Sugawara; Michiya Kobayashi; Yoh Takekuma; Katsumi Miyazaki
An in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs.
International journal of pharmaceutics 2003;263(1-2):35-44.
2003: Mitsuru Sugawara; Toru Ogawa; Michiya Kobayashi; Katsumi Miyazaki
Uptake of dipeptide and beta-lactam antibiotics by the basolateral membrane vesicles prepared from rat kidney.
Biochimica et biophysica acta 2003;1609(1):39-44.
2003: Mitsuru Sugawara; Masaya Kato; Mayumi Kitakubo; Yoh Takekuma; Vadivel Ganapathy; Katsumi Miyazaki
Inhibitory effects of basic drugs on the sodium-dependent transport of L-alanine via system B0 in the small intestine.
Drug metabolism and pharmacokinetics 2003;18(3):186-93.
2002: Satoshi Kishino; Akikazu Nomura; Shin Itoh; Tsutomu Nakagawa; Yoh Takekuma; Mitsuru Sugawara; Hiroyuki Furukawa; Satoru Todo; Katsumi Miyazaki
Age- and gender-related differences in carbohydrate concentrations of alpha1-acid glycoprotein variants and the effects of glycoforms on their drug-binding capacities.
European journal of clinical pharmacology 2002;58(9):621-8.
2002: Satoshi Kishino; Yoh Takekuma; Mitsuru Sugawara; Tsuyoshi Shimamura; Hiroyuki Furukawa; Satoru Todo; Katsumi Miyazaki
Liquid chromatographic method for the determination of ganciclovir and/or acyclovir in human plasma using pulsed amperometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;780(2):289-94.
2002: Mitsuru Sugawara; Megumi Kurosawa; Kasumi Sakai; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Ionic strength has a greater effect than does transmembrane electric potential difference on permeation of tryptamine and indoleacetic acid across Caco-2 cells.
Biochimica et biophysica acta 2002;1564(1):149-55.
2001: Michiya Kobayashi; N Sada; Mitsuru Sugawara; K Iseki; Katsumi Miyazaki
Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract.
International journal of pharmaceutics 2001;221(1-2):87-94.
1999: Michiya Kobayashi; Hiroko Fujisaki; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
Effects of interactions between drugs on the renal excretion of trientine in rats--acetazolamide and furosemide increase trientine excretion.
Pharmaceutical research 1999;16(12):1888-92.
1999: Ken Iseki; Mitsuru Sugawara; K Sato; I Naasani; T Hayakawa; Michiya Kobayashi; Katsumi Miyazaki
Multiplicity of the H+-dependent transport mechanism of dipeptide and anionic beta-lactam antibiotic ceftibuten in rat intestinal brush-border membrane.
The Journal of pharmacology and experimental therapeutics 1999;289(1):66-71.
1999: Michiya Kobayashi; Hiroko Fujisaki; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
The presence of an Na+/spermine antiporter in the rat renal brush-border membrane.
The Journal of pharmacy and pharmacology 1999;51(3):279-84.
1998: Mitsuru Sugawara; Yoh Takekuma; H Yamada; M Kobayashi; Ken Iseki; Katsumi Miyazaki
A general approach for the prediction of the intestinal absorption of drugs: regression analysis using the physicochemical properties and drug-membrane electrostatic interaction.
Journal of pharmaceutical sciences 1998;87(8):960-6.
1998: Ken Iseki; T Hirano; K Tsuji; S Miyazaki; M Takada; Michiya Kobayashi; Mitsuru Sugawara; Katsumi Miyazaki
Ionic-diffusion potential-dependent transport of a new quinolone, sparfloxacin, across rat intestinal brush-border membrane.
The Journal of pharmacy and pharmacology 1998;50(6):627-34.
1998: Mitsuru Sugawara; M Kato; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Mechanism of the inhibitory effect of imipramine on the Na+-dependent transport of L-glutamic acid in rat intestinal brush-border membrane.
Biochimica et biophysica acta 1998;1370(2):252-8.
1998: Ken Iseki; K Yonemura; T Kikuchi; I Naasani; Mitsuru Sugawara; Michiya Kobayashi; N Kohri; Katsumi Miyazaki
Purification by ceftibuten-affinity chromatography and the functional reconstitution of oligopeptide transporter(s) in rat intestinal brush-border membrane.
Biochimica et biophysica acta 1998;1370(1):161-8.
1998: Ken Iseki; I Naasani; T Kikuchi; Mitsuru Sugawara; Michiya Kobayashi; N Kohri; Katsumi Miyazaki
Purification and liposomal reconstitution of the oligopeptide transport activity in rat renal cortex using ceftibuten-affinity chromatography.
Biochimica et biophysica acta 1998;1368(2):329-37.
1997: Satoshi Kishino; Akikazu Nomura; M Saitoh; Mitsuru Sugawara; K Iseki; A Kitabatake; Katsumi Miyazaki
Single-step isolation method for six glycoforms of human alpha1-acid glycoprotein by hydroxylapatite chromatography and study of their binding capacities for disopyramide.
Journal of chromatography. B, Biomedical sciences and applications 1997;703(1-2):1-6.
1997: Ken Iseki; K Kaido; Michiya Kobayashi; Mitsuru Sugawara; Katsumi Miyazaki
The effect of membrane surface potential on the permeability of anionic compounds across the apical membrane in human intestinal epithelial (Caco-2) cells.
Biological & pharmaceutical bulletin 1997;20(7):794-9.
1997: Michiya Kobayashi; S Suruga; H Takeuchi; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
A structure-relationship study of the uptake of aliphatic polyamine compounds by rat intestinal brush-border membrane vesicles.
The Journal of pharmacy and pharmacology 1997;49(5):511-5.
1997: Michiya Kobayashi; R Tanabe; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
The mechanism of excretion of trientine from the rat kidney: trientine is not recognized by the H+/organic cation transporter.
The Journal of pharmacy and pharmacology 1997;49(4):426-9.
1996: I Naasani; T Kikuchi; Mitsuru Sugawara; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Solubilization and reconstitution characteristics of the carrier protein(s) responsible for the transport of ceftibuten, a substrate for the oligopeptide transporters, in rat renal brush-border membrane.
Biochimica et biophysica acta 1996;1283(2):185-91.
1996: R Tanabe; Michiya Kobayashi; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
Uptake mechanism of trientine by rat intestinal brush-border membrane vesicles.
The Journal of pharmacy and pharmacology 1996;48(5):517-21.
1996: Ken Iseki; Mitsuru Sugawara; T Fujiwara; I Naasani; Michiya Kobayashi; Katsumi Miyazaki
Transport mechanisms of nucleosides and the derivative, 6-mercaptopurine riboside across rate intestinal brush-border membranes.
Biochimica et biophysica acta 1996;1278(1):105-10.
1995: Satoshi Kishino; A Nomura; Mitsuru Sugawara; Ken Iseki; S Kakinoki; A Kitabatake; Katsumi Miyazaki
Purification method for alpha-1-acid glycoprotein with subsequent high-performance liquid chromatographic determination of monosaccharides in plasma of healthy subjects and patients with renal insufficiency.
Journal of chromatography. B, Biomedical applications 1995;672(2):199-205.
1995: Satoshi Kishino; A Nomura; Z S Di; Mitsuru Sugawara; Ken Iseki; S Kakinoki; A Kitabatake; Katsumi Miyazaki
Changes in the binding capacity of alpha-1-acid glycoprotein in patients with renal insufficiency.
Therapeutic drug monitoring 1995;17(5):449-53.
1995: I Naasani; K Sato; Ken Iseki; Mitsuru Sugawara; Michiya Kobayashi; Katsumi Miyazaki
Comparison of the transport characteristics of ceftibuten in rat renal and intestinal brush-border membranes.
Biochimica et biophysica acta 1995;1231(2):163-8.
1995: T Hirano; Ken Iseki; I Sato; S Miyazaki; M Takada; Michiya Kobayashi; Mitsuru Sugawara; Katsumi Miyazaki
The intestinal transport mechanism of fluoroquinolones: inhibitory effect of ciprofloxacin, an enoxacin derivative, on the membrane potential-dependent uptake of enoxacin.
Pharmaceutical research 1995;12(9):1299-303.
1995: Satoshi Kishino; A Nomura; Z S Di; Mitsuru Sugawara; Ken Iseki; S Kakinoki; A Kitabatake; Katsumi Miyazaki
Alpha-1-acid glycoprotein concentration and the protein binding of disopyramide in healthy subjects.
Journal of clinical pharmacology 1995;35(5):510-4.
1995: I Naasani; Mitsuru Sugawara; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Transport mechanism of ceftibuten, a dianionic cephem, in rat renal brush-border membrane.
Pharmaceutical research 1995;12(4):605-8.
1995: Mitsuru Sugawara; H Oikawa; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Effect of membrane surface potential on the uptake and the inhibition of cationic compounds in rat intestinal brush-border membrane vesicles and liposomes.
Biochimica et biophysica acta 1995;1234(1):22-8.
1994: Mitsuru Sugawara; T Toda; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki; H Shiroto; J Uchino; Y Kondo
The inhibitory effects of cephalosporin and dipeptide on ceftibuten uptake by human and rat intestinal brush-border membrane vesicles.
The Journal of pharmacy and pharmacology 1994;46(8):680-4.
1994: T Hirano; Ken Iseki; S Miyazaki; M Takada; Michiya Kobayashi; Mitsuru Sugawara; Katsumi Miyazaki
The stimulative effect of diffusion potential on enoxacin uptake across rat intestinal brush-border membranes.
The Journal of pharmacy and pharmacology 1994;46(8):676-9.
1994: Mitsuru Sugawara; A Hashimoto; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Effect of membrane surface potential on the uptake of anionic compounds by liposomes.
Biochimica et biophysica acta 1994;1192(2):241-6.
1994: Ken Iseki; Y Satoh; Mitsuru Sugawara; Katsumi Miyazaki
[Effect of Enterued administration on the intestinal absorption of orally active cefem antibiotics].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(4):233-40.
1994: Mitsuru Sugawara; A Hashimoto; T Toda; M Takahashi; Michiya Kobayashi; Ken Iseki; Katsumi Miyazaki
Changes in the permeation rate of organic anions through the intestinal brush-border membrane with membrane surface potential.
Biochimica et biophysica acta 1994;1190(1):85-90.
1993: Ken Iseki; Mitsuru Sugawara; N Saitoh; Katsumi Miyazaki
The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. II. Comparison of the membrane potential effect on the uptake by membrane vesicles.
Biochimica et biophysica acta 1993;1152(1):9-14.
1993: Michiya Kobayashi; Ken Iseki; Mitsuru Sugawara; Katsumi Miyazaki
The diversity of Na(+)-independent uptake systems for polyamines in rat intestinal brush-border membrane vesicles.
Biochimica et biophysica acta 1993;1151(2):161-7.
1993: Ken Iseki; Mitsuru Sugawara; N Saitoh; Katsumi Miyazaki
The transport mechanisms of organic cations and their zwitterionic derivatives across rat intestinal brush-border membrane. 1. Binding characteristics to the bio- and lipid-membranes.
Biochimica et biophysica acta 1993;1146(1):121-6.
1992: Mitsuru Sugawara; T Toda; Ken Iseki; Katsumi Miyazaki; H Shiroto; Y Kondo; J Uchino
Transport characteristics of cephalosporin antibiotics across intestinal brush-border membrane in man, rat and rabbit.
The Journal of pharmacy and pharmacology 1992;44(12):968-72.
1992: Hiroshi Saitoh; Michiya Kobayashi; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
Carrier-mediated transport system for choline and its related quaternary ammonium compounds on rat intestinal brush-border membrane.
Biochimica et biophysica acta 1992;1112(1):153-60.
1992: Mitsuru Sugawara; M Sasaki; Ken Iseki; Katsumi Miyazaki
Membrane-potential-dependent uptake of tryptamine by rat intestinal brush-border membrane vesicles.
Biochimica et biophysica acta 1992;1111(2):145-50.
1992: Satoshi Kishino; Z S Di; Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki; S Kakinoki; A Homura; A Kitabatake
Rapid and simple method for the determination of alpha 1-acid glycoprotein in serum by column liquid chromatography.
Journal of chromatography 1992;582(1-2):246-8.
1992: Ken Iseki; T Hirano; Y Fukushi; Y Kitamura; S Miyazaki; M Takada; Mitsuru Sugawara; Hiroshi Saitoh; Katsumi Miyazaki
The pH dependent uptake of enoxacin by rat intestinal brush-border membrane vesicles.
The Journal of pharmacy and pharmacology 1992;44(9):722-6.
1991: Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki; H Shiroto; Y Kondo; J Uchino
Transport characteristics of ceftibuten, cefixime and cephalexin across human jejunal brush-border membrane.
The Journal of pharmacy and pharmacology 1991;43(12):882-4.
1991: Mitsuru Sugawara; Ken Iseki; Katsumi Miyazaki
H+ coupled transport of orally active cephalosporins lacking an alpha-amino group across brush-border membrane vesicles from rat small intestine.
The Journal of pharmacy and pharmacology 1991;43(6):433-5.
1990: Michiya Kobayashi; Mitsuru Sugawara; Hiroshi Saitoh; Ken Iseki; Katsumi Miyazaki
[Intestinal absorption and urinary excretion of triethylenetetramine for Wilson's disease in rat].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1990;110(10):759-63.
1990: Mitsuru Sugawara; Hiroshi Saitoh; Ken Iseki; Katsumi Miyazaki; T Arita
Contribution of passive transport mechanisms to the intestinal absorption of beta-lactam antibiotics.
The Journal of pharmacy and pharmacology 1990;42(5):314-8.
1989: Ken Iseki; Mitsuru Sugawara; Hiroshi Saitoh; Katsumi Miyazaki; T Arita
Comparison of transport characteristics of amino beta-lactam antibiotics and dipeptides across rat intestinal brush border membrane.
The Journal of pharmacy and pharmacology 1989;41(9):628-32.
1988: Ken Iseki; Mitsuru Sugawara; Hiroshi Saitoh; Katsumi Miyazaki; T Arita
Effect of chlorpromazine on the permeability of beta-lactam antibiotics across rat intestinal brush border membrane vesicles.
The Journal of pharmacy and pharmacology 1988;40(10):701-5.