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Toshitsugu Sugimoto

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Toshitsugu Sugimoto; Tetsuo Nakano; Masataka Shiraki; Teruki Sone; Masao Fukunaga; Hiroshi Hagino; Masako Ito; Hideaki Kishimoto; Tatsuhiko Kuroda; Toshitaka Nakamura
Vertebral fracture risk after once-weekly teriparatide injections: follow-up study of Teriparatide Once-Weekly Efficacy Research (TOWER) trial.
Ippei Kanazawa; N Ogawa; K Tanaka; Toru Yamaguchi; Mika Yamauchi; Toshitsugu Sugimoto
Undercarboxylated osteocalcin is positively associated with free testosterone in male patients with type 2 diabetes mellitus.
Ippei Kanazawa; Toshitsugu Sugimoto
[The relationship between bone and glucose/lipid metabolism].

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2013: Toshitsugu Sugimoto; Tetsuo Nakano; Masataka Shiraki; Teruki Sone; Masao Fukunaga; Hiroshi Hagino; Masako Ito; Hideaki Kishimoto; Tatsuhiko Kuroda; Toshitaka Nakamura
Vertebral fracture risk after once-weekly teriparatide injections: follow-up study of Teriparatide Once-Weekly Efficacy Research (TOWER) trial.
Current medical research and opinion 2013;29(3):195-203.
2013: Ippei Kanazawa; N Ogawa; K Tanaka; Toru Yamaguchi; Mika Yamauchi; Toshitsugu Sugimoto
Undercarboxylated osteocalcin is positively associated with free testosterone in male patients with type 2 diabetes mellitus.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2013;24(3):1115-9.
2013: Ippei Kanazawa; Toshitsugu Sugimoto
[The relationship between bone and glucose/lipid metabolism].
Clinical calcium 2013;23(2):181-8.
2013: Shin Takaoka; Ken-Ichiro Tanaka; Toru Yamaguchi; Masahiro Yamamoto; Mika Yamauchi; Shozo Yano; Miwa Morita; Toshitsugu Sugimoto
Fracture risk is increased by the complication of hypertension and treatment with calcium channel blockers in postmenopausal women with type 2 diabetes.
Journal of bone and mineral metabolism 2013;31(1):102-7.
2013: Miwa Morita; Toru Yamaguchi; Shozo Yano; Toshitsugu Sugimoto
Advanced glycation end products-induced reactive oxygen species generation is partly through NF-kappa B activation in human aortic endothelial cells.
Journal of diabetes and its complications 2013;27(1):11-5.
2012: Kyoko Okazaki; Masakazu Notsu; Noriko Ogawa; Ken-Ichiro Tanaka; Toru Yamaguchi; Shozo Yano; Toshitsugu Sugimoto
Advanced glycation end products (AGEs), but not high glucose, inhibit the osteoblastic differentiation of mouse stromal ST2 cells through the suppression of osterix expression, and inhibit cell growth and increasing cell apoptosis.
Calcified tissue international 2012;91(4):286-96.
2012: Toshitsugu Sugimoto
[109th Scientific Meeting of the Japanese Society of Internal Medicine: educational lecture: 1. Progress in the treatment of osteoporosis].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2012;101(9):2636-42.
2012: Masato Yano; Susumu Seino; Toshitsugu Sugimoto; Takako Tobimatsu; Lucie Canaff; Geoffrey Hendy; Yoshifumi Inoue; Hiroshi Kaji
Smad7 inhibits differentiation and mineralization of mouse osteoblastic cells.
Endocrine journal 2012;59(8):653-62.
2012: Shozo Yano; Toshitsugu Sugimoto
[Side-effects of therapeutic agents for osteoporosis].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 6():224-9.
2012: Ken-ichiro Tanaka; Lucie Canaff; Geoffrey N Hendy; Yoshifumi Inoue; Takenobu Katagiri; Riko Kitazawa; Toshihisa Komori; Susumu Seino; Toshitsugu Sugimoto; Hiroshi Kaji
Interaction of Tmem119 and the bone morphogenetic protein pathway in the commitment of myoblastic into osteoblastic cells.
Bone 2012;51(1):158-67.
2012: Ken-ichiro Tanaka; Yoshiko Higashimaki; Takenobu Katagiri; Erika Matsumoto; Susumu Seino; Toshitsugu Sugimoto; Hiroshi Kaji
Role of osteoglycin in the linkage between muscle and bone.
The Journal of biological chemistry 2012;287(15):11616-28.
2012: Masahiro Yamamoto; Mika Yamauchi; Kiyoko Nawata; Toru Yamaguchi; Toshitsugu Sugimoto
Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2012;97(4):1277-84.
2012: Ken-ichiro Tanaka; Yoshiko Higashimaki; Erika Matsumoto; Susumu Seino; Toshitsugu Sugimoto; Hiroshi Kaji
FAM5C is a soluble osteoblast differentiation factor linking muscle to bone.
Biochemical and biophysical research communications 2012;418(1):134-9.
2012: Ken-ichiro Tanaka; Toru Yamaguchi; Mika Yamauchi; Shozo Yano; Yasutoshi Himeno; Keisuke Okuyama; Masatake Sato; Kazuaki Tanabe; Toshitsugu Sugimoto
Hypercalcemia associated with eosinophilic myocarditis in a patient undergoing maintenance hemodialysis.
Internal medicine (Tokyo, Japan) 2012;51(20):2913-6.
2012: Ken-ichiro Tanaka; Toru Yamaguchi; Masahiro Yamamoto; Kyoko Okazaki; Toshitsugu Sugimoto
Partial improvement of anterior pituitary deficiency following steroid treatment in a patient with neurosarcoidosis accompanied by central diabetes insipidus.
Internal medicine (Tokyo, Japan) 2012;51(16):2175-9.
2011: Hiroshi Kaji; Y Imanishi; Toshitsugu Sugimoto; S Seino
Comparisons of serum sclerostin levels among patients with postmenopausal osteoporosis, primary hyperparathyroidism and osteomalacia.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2011;119(7):440-4.
2011: Itoko Hisa; Yoshifumi Inoue; Geoffrey N Hendy; Lucie Canaff; Riko Kitazawa; Sohei Kitazawa; Toshihisa Komori; Toshitsugu Sugimoto; Susumu Seino; Hiroshi Kaji
Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway.
The Journal of biological chemistry 2011;286(11):9787-96.
2010: Hiroshi Kaji; Toshitsugu Sugimoto
[Cytokines in bone diseases. Bone anabolic action of PTH and role of cytokine].
Clinical calcium 2010;20(10):1555-61.
2010: Hiroshi Kaji; Mika Yamauchi; Toru Yamaguchi; Takashi Shigematsu; Toshitsugu Sugimoto
Mild renal dysfunction is a risk factor for a decrease in bone mineral density and vertebral fractures in Japanese postmenopausal women.
The Journal of clinical endocrinology and metabolism 2010;95(10):4635-42.
2010: Hiroshi Kaji; Mika Yamauchi; Toru Yamaguchi; Toshitsugu Sugimoto
Urinary deoxypyridinoline is a BMD-independent marker for prevalent vertebral fractures in postmenopausal women treated with glucocorticoid.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2010;21(9):1585-90.
2010: Hiroshi Kaji; Y Kuroki; Y Murakawa; I Funakawa; Y Funasaka; Fumio Kanda; Toshitsugu Sugimoto
Effect of alendronate on bone metabolic indices and bone mineral density in patients treated with high-dose glucocorticoid: a prospective study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2010;21(9):1565-71.
2010: Hiroshi Kaji; I Hisa; Y Inoue; Toshitsugu Sugimoto
Low density lipoprotein-cholesterol levels affect vertebral fracture risk in female patients with primary hyperparathyroidism.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2010;118(6):371-6.
2009: Hiroshi Kaji; Mika Yamauchi; Rikako Nomura; Toshitsugu Sugimoto
Two-year longitudinal changes in forearm cortical bone geometry in postmenopausal women with mild primary hyperparathyroidism without parathyroidectomy.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2009;117(10):633-6.
2009: Yoshifumi Inoue; Lucie Canaff; Geoffrey N Hendy; Itoko Hisa; Toshitsugu Sugimoto; Kazuo Chihara; Hiroshi Kaji
Role of Smad3, acting independently of transforming growth factor-beta, in the early induction of Wnt-beta-catenin signaling by parathyroid hormone in mouse osteoblastic cells.
Journal of cellular biochemistry 2009;108(1):285-94.
2009: Hiroshi Kaji; Itoko Hisa; Yoshifumi Inoue; Junko Naito; Toshitsugu Sugimoto; Masato Kasuga
Analysis of factors affecting increase in bone mineral density at lumbar spine by bisphosphonate treatment in postmenopausal osteoporosis.
Journal of bone and mineral metabolism 2009;27(1):76-82.
2008: Hiroshi Kaji; Junko Naito; Yoshihisa Inoue; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(11):746-51.
2008: Hiroshi Kaji; Mika Yamauchi; Rikako Nomura; Toshitsugu Sugimoto
Improved peripheral cortical bone geometry after surgical treatment of primary hyperparathyroidism in postmenopausal women.
The Journal of clinical endocrinology and metabolism 2008;93(8):3045-50.
2008: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
Glucocorticoid excess affects cortical bone geometry in premenopausal, but not postmenopausal, women.
Calcified tissue international 2008;82(3):182-90.
2008: Yoshifumi Inoue; Hiroshi Kaji; Itoko Hisa; Takako Tobimatsu; Junko Naito; Mei-Fway Iu; Toshitsugu Sugimoto; Kazuo Chihara
Vitamin D status affects osteopenia in postmenopausal patients with primary hyperparathyroidism.
Endocrine journal 2008;55(1):57-65.
2008: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
Relationship between endogenous parathyroid hormone and bone metabolism/geometry in female patients treated with glucocorticoid.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(1):60-5.
2006: Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Serum soluble factors induce the proliferation, alkaline phosphatase activity and transforming growth factor-beta signal in osteoblastic cells in the patient with hepatitis C-associated osteosclerosis.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2006;114(10):599-604.
2006: Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Smad3 differently affects osteoblast differentiation depending upon its differentiation stage.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(11):740-5.
2006: Go Inokuchi; Hitoshi Tanimoto; Haruhiko Ishida; Toshitsugu Sugimoto; Mika Yamauchi; Akimitsu Miyauchi; Ken-ichi Nibu
A paranasal tumor associated with tumor-induced osteomalacia.
The Laryngoscope 2006;116(10):1930-3.
2006: Hiroshi Kaji; Toshitsugu Sugimoto
[Multiple endocrine neoplasia type I].
Nihon rinsho. Japanese journal of clinical medicine 2006;Suppl 3():333-6.
2006: Hiroshi Kaji; Toshitsugu Sugimoto
[Anabolic treatment for osteoporosis: PTH treatment].
Clinical calcium 2006;16(9):1480-85.
2006: Junko Naito; Hiroshi Kaji; Hideaki Sowa; Riko Kitazawa; Sohei Kitazawa; Toshihiko Tsukada; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Expression and functional analysis of menin in a multiple endocrine neoplasia type 1 (MEN1) patient with somatic loss of heterozygosity in chromosome 11q13 and unidentified germline mutation of the MEN1 gene.
Endocrine 2006;29(3):485-90.
2006: Hiroshi Kaji; Rikako Nomura; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The usefulness of bone metabolic indices for the prediction of changes in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(6):411-6.
2006: Takako Tobimatsu; Hiroshi Kaji; Hideaki Sowa; Junko Naito; Lucie Canaff; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells.
Endocrinology 2006;147(5):2583-90.
2006: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The threshold of bone mineral density for vertebral fracture in female patients with glucocorticoid-induced osteoporosis.
Endocrine journal 2006;53(1):27-34.
2006: Hiroshi Kaji; Mei-Fway Iu; Junko Naito; Toshitsugu Sugimoto; Kazuo Chihara
A case of primary hyperparathyroidism with marked changes in bone mineral density and geometry after parathyroidectomy.
Journal of bone and mineral metabolism 2006;24(4):349-52.
2006: Hiroshi Kaji; Takako Tobimatsu; Junko Naito; Mei-Fway Iu; Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara
Body composition and vertebral fracture risk in female patients treated with glucocorticoid.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2006;17(4):627-33.
2005: Hiroshi Kaji; Rieko Kosaka; Mika Yamauchi; Kaoru Kuno; Kazuo Chihara; Toshitsugu Sugimoto
Effects of age, grip strength and smoking on forearm volumetric bone mineral density and bone geometry by peripheral quantitative computed tomography: comparisons between female and male.
Endocrine journal 2005;52(6):659-66.
2005: Hiroshi Kaji; Masanori Kanatani; Toshitsugu Sugimoto; Kazuo Chihara
Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(10):589-92.
2005: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The threshold of bone mineral density for vertebral fractures in female patients with primary hyperparathyroidism.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(3):373-8.
2005: Hiroshi Kaji; Toshitsugu Sugimoto
[The mechanism of parathyroid hormone action].
Clinical calcium 2005;15(7):93-7.
2005: Hiroshi Kaji; Toshitsugu Sugimoto
[The genes related to the effects of vitamin D on muscle and bone].
Clinical calcium 2005;15(5):834-8.
2005: Mei-Fway Iu; Hiroshi Kaji; Hideaki Sowa; Junko Naito; Toshitsugu Sugimoto; Kazuo Chihara
Dexamethasone suppresses Smad3 pathway in osteoblastic cells.
The Journal of endocrinology 2005;185(1):131-8.
2005: Hiroshi Kaji; Toshitsugu Sugimoto
[Treatment of osteoporosis with parathyroid hormone: evidence and perspective].
Clinical calcium 2005;15(4):611-5.
2005: Junko Naito; Hiroshi Kaji; Hideaki Sowa; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.
The Journal of biological chemistry 2005;280(6):4785-91.
2005: Mei-Fway Iu; Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Low-dose parathyroid hormone and estrogen reverse alkaline phosphatase activity suppressed by dexamethasone in mouse osteoblastic cells.
Journal of bone and mineral metabolism 2005;23(6):450-5.
2004: Takako Tobimatsu; Hiroshi Kaji; Junko Naito; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara; Toshihiko Tsukada
[Case Report No.143: one case of multiple endosecretory-adenomatosis accompanied with ventricula ependymoma].
Clinical calcium 2004;14(10):150-3.
2004: Q Chen; Hiroshi Kaji; Masanori Kanatani; Toshitsugu Sugimoto; Kazuo Chihara
Testosterone increases osteoprotegerin mRNA expression in mouse osteoblast cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(10):674-8.
2004: Masanori Kanatani; Toshitsugu Sugimoto; Hideaki Sowa; Tatsuya Kobayashi; Michiko Kanzawa; Kazuo Chihara
Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction.
Journal of cellular physiology 2004;201(1):17-25.
2004: Hideaki Sowa; Hiroshi Kaji; Geoffrey N Hendy; Lucie Canaff; Toshihisa Komori; Toshitsugu Sugimoto; Kazuo Chihara
Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
The Journal of biological chemistry 2004;279(39):40267-75.
2004: Hideaki Sowa; Hiroshi Kaji; Riko Kitazawa; Sohei Kitazawa; Tatsuo Tsukamoto; Shozo Yano; Toshihiko Tsukada; Lucie Canaff; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Menin inactivation leads to loss of transforming growth factor beta inhibition of parathyroid cell proliferation and parathyroid hormone secretion.
Cancer research 2004;64(6):2222-8.
2004: Rikako Nomura; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Toru Yamaguchi; Akira Kobayashi; Kazuo Chihara
Marked and sustained increase in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism; a six-year longitudinal study with or without parathyroidectomy in a Japanese population.
Clinical endocrinology 2004;60(3):335-42.
2004: Mika Yamauchi; Takeshi Sugishita; Toshitsugu Sugimoto
[pQCT].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 2():290-4.
2004: Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara
Determinants of vertebral fragility: the participation of cortical bone factors.
Journal of bone and mineral metabolism 2004;22(2):79-85.
2003: Hideaki Sowa; Hiroshi Kaji; Mei-Fway Iu; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts.
The Journal of biological chemistry 2003;278(52):52240-52.
2003: Hiroshi Kaji; Toshitsugu Sugimoto
[SERM and SARM].
Clinical calcium 2003;13(11):1463-6.
2003: Qingxiang Chen; Hiroshi Kaji; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Tatsuo Tsukamoto; Toru Yamaguchi; Akira Kobayashi; Toshitsugu Sugimoto; Kazuo Chihara
Trial to predict malignancy of affected parathyroid glands in primary hyperparathyroidism.
Endocrine journal 2003;50(5):527-34.
2003: Qingxiang Chen; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects.
The Journal of clinical endocrinology and metabolism 2003;88(10):4655-8.
2003: Junko Naito; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Qingxiang Chen; Mika Yamauchi; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
[In Process Citation].
Clinical calcium 2003;13(8):1072-6.
2003: Masanori Kanatani; Toshitsugu Sugimoto; Junichi Kano; Michiko Kanzawa; Kazuo Chihara
Effect of high phosphate concentration on osteoclast differentiation as well as bone-resorbing activity.
Journal of cellular physiology 2003;196(1):180-9.
2003: Hideaki Sowa; Hiroshi Kaji; Lucie Canaff; Geoffrey N Hendy; Tatsuo Tsukamoto; Toru Yamaguchi; Kohei Miyazono; Toshitsugu Sugimoto; Kazuo Chihara
Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage.
The Journal of biological chemistry 2003;278(23):21058-69.
2003: Qingxiang Chen; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sawa; Mika Yamauchi; Tatsuo Tsukamoto; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara; Riko Kitazawa; Akira Kobayashi
[In Process Citation].
Clinical calcium 2003;13(4):496-9.
2003: Tetsuya Makino; Toshitsugu Sugimoto; Hiroshi Kaji; Toru Yamaguchi; Riko Kitazawa; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Rikako Nomura; Tatsuo Tsukamoto; Kazuo Chihara
Functional giant parathyroid cyst with high concentration of CA19-9 in cystic fluid.
Endocrine journal 2003;50(2):215-9.
2003: Hiroshi Kaji; Saburo Hattori; Kenichi Sekita; Toshitsugu Sugimoto; Kazuo Chihara
Factors affecting bone mineral density in hemodialysis patients with diabetic nephropathy.
Endocrine journal 2003;50(2):127-33.
2003: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Toru Yamaguchi; T Hattori; KI Sekita; Hiroshi Kaji; S Hattori; Akiko Kobayashi; Kazuo Chihara
Effect of parathyroidectomy on bone mineral density in hemodialysis patients with secondary hyperparathyroidism: possible usefulness of preoperative determination of parathyroid hormone level for prediction of bone regain.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(4):259-64.
2003: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Kazuo Chihara; Akira Kobayashi; Sohei Kitazawa; Sakan Maeda; Riko Kitazawa
Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(4):403-11.
2003: Toshitsugu Sugimoto
[Osteoporosis associated with primary hyperparathyroidism].
Nihon rinsho. Japanese journal of clinical medicine 2003;61(2):299-304.
2002: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Shozo Yano; Junning Wang; Mei Bai; Edward M Brown; Kazuo Chihara
Familial hypocalciuric hypercalcemia caused by an R648stop mutation in the calcium-sensing receptor gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(12):2174-82.
2002: Mika Yamauchi; Toshitsugu Sugimoto
[Significance of bone mass measurement in glucocorticoid-induced osteoporosis].
Clinical calcium 2002;12(11):1565-9.
2002: Hideaki Sowa; Hiroshi Kaji; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.
The Journal of biological chemistry 2002;277(39):36024-31.
2002: Toshitsugu Sugimoto; Hiroshi Kaji; Daiki Nakaoka; Mika Yamauchi; Shozo Yano; Takeshi Sugishita; David J Baylink; Subburaman Mohan; Kazuo Chihara
Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):339-48.
2002: Hideaki Sowa; Hiroshi Kaji; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Smad3 promotes alkaline phosphatase activity and mineralization of osteoblastic MC3T3-E1 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(7):1190-9.
2002: Rieko Ozuru; Toshitsugu Sugimoto; Tohru Yamaguchi; Kazuo Chihara
Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women.
Endocrine journal 2002;49(3):363-70.
2002: Toru Yamaguchi; Toshitsugu Sugimoto; Shozo Yano; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Kazuo Chihara
Plasma lipids and osteoporosis in postmenopausal women.
Endocrine journal 2002;49(2):211-7.
2002: Toshitsugu Sugimoto
[PTH injection for the treatment of osteoporosis].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 3():544-51.
2002: Masanori Kanatani; Toshitsugu Sugimoto; Junichi Kano; Kazuo Chihara
IGF-I mediates the stimulatory effect of high phosphate concentration on osteoblastic cell proliferation.
Journal of cellular physiology 2002;190(3):306-12.
2002: Toru Yamaguchi; Toshitsugu Sugimoto; H Yamada; Michiko Kanzawa; Shozo Yano; Mika Yamauchi; Kazuo Chihara
The presence and severity of vertebral fractures is associated with the presence of esophageal hiatal hernia in postmenopausal women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2002;13(4):331-6.
2002: Riko Kitazawa; Sohei Kitazawa; Kazuyoshi Kajimoto; Hideaki Sowa; Toshitsugu Sugimoto; Tosimitsu Matsui; Kazuo Chihara; Sakan Maeda
Expression of parathyroid hormone-related protein (PTHrP) in multiple myeloma.
Pathology international 2002;52(1):63-8.
2002: Yonson Ku; Masahiro Tominaga; Toshitsugu Sugimoto; Takeshi Iwasaki; Takumi Fukumoto; T Takahashi; Yasuyuki Suzuki; Yoshikazu Kuroda
Preoperative hepatic venous embolization for partial hepatectomy combined with segmental resection of major hepatic vein.
The British journal of surgery 2002;89(1):63-9.
2001: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Shozo Yano; Michiko Kanzawa; Akiko Kobayashi; Kazuo Chihara
Association of polymorphic alleles of the calcium-sensing receptor gene with the clinical severity of primary hyperparathyroidism.
Clinical endocrinology 2001;55(3):373-9.
2001: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Daiki Nakaoka; Michiko Kanzawa; Shozo Yano; R Ozuru; Takeshi Sugishita; Kazuo Chihara
Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women.
Clinical endocrinology 2001;55(3):341-7.
2001: Y Tokukoda; S Takata; Hiroshi Kaji; Riko Kitazawa; Toshitsugu Sugimoto; Kazuo Chihara
Interleukin-1beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts.
Endocrine journal 2001;48(4):443-52.
2001: Hiroshi Kaji; Toshitsugu Sugimoto; Daiki Nakaoka; Yasuhiko Okimura; H Kaji; H Abe; Kazuo Chihara
Bone metabolism and body composition in Japanese patients with active acromegaly.
Clinical endocrinology 2001;55(2):175-81.
2001: Y Morimoto; Toshitsugu Sugimoto; T Mukai; Yutaka Okita; Morihito Okada
Diagnosis of deep vein thrombosis using platelet scintigraphy.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2001;7(3):138-42.
2001: Nobuya Kusunoki; Yonson Ku; Masahiro Tominaga; Takeshi Iwasaki; Takumi Fukumoto; Sanshiro Muramatsu; Toshitsugu Sugimoto; Shinobu Tsuchida; M Takamatsu; Yasuyuki Suzuki; Yoshikazu Kuroda
Effect of sodium thiosulfate on cisplatin removal with complete hepatic venous isolation and extracorporeal charcoal hemoperfusion: a pharmacokinetic evaluation.
Annals of surgical oncology 2001;8(5):449-57.
2001: Tetsuji Yamamoto; Masahiro Kurosaka; Toshitsugu Sugimoto
A true aneurysm of the femoral artery in acromegaly.
Clinical imaging 2001;25(2):126-9.
2001: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; K Ikeda; Kazuo Chihara
Skeletal responsiveness to parathyroid hormone in pseudohypoparathyroidism.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(3):263-9.
2001: Q Chen; Hiroshi Kaji; Toshitsugu Sugimoto; Kazuo Chihara
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor.
FEBS letters 2001;491(1-2):91-3.
2001: Toshitsugu Sugimoto
[Calcium intake and bone mass].
Clinical calcium 2001;11(2):193-7.
2001: Daiki Nakaoka; Toshitsugu Sugimoto; Hiroshi Kaji; Michiko Kanzawa; Shozo Yano; Mika Yamauchi; Takeshi Sugishita; Kazuo Chihara
Determinants of bone mineral density and spinal fracture risk in postmenopausal Japanese women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2001;12(7):548-54.
2000: M Nasu; Toshitsugu Sugimoto; Hiroshi Kaji; Kazuo Chihara
Estrogen modulates osteoblast proliferation and function regulated by parathyroid hormone in osteoblastic SaOS-2 cells: role of insulin-like growth factor (IGF)-I and IGF-binding protein-5.
The Journal of endocrinology 2000;167(2):305-13.
2000: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Kazuo Chihara; Akiko Kobayashi; Sohei Kitazawa; Sakan Maeda; Riko Kitazawa
Association of decreased calcium-sensing receptor expression with proliferation of parathyroid cells in secondary hyperparathyroidism.
Kidney international 2000;58(5):1980-6.
2000: Michiko Kanzawa; Toshitsugu Sugimoto; Tatsuya Kobayashi; Akiko Kobayashi; Kazuo Chihara
Association between parathyroid hormone (PTH)/PTH-related peptide receptor gene polymorphism and the extent of bone mass reduction in primary hyperparathyroidism.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(9):355-8.
2000: Shozo Yano; Toshitsugu Sugimoto; Michiko Kanzawa; Tatsuo Tsukamoto; T Hattori; S Hattori; Kazuo Chihara
Association of polymorphic alleles of the calcium-sensing receptor gene with parathyroid hormone secretion in hemodialysis patients.
Nephron 2000;85(4):317-23.
2000: Daiki Nakaoka; Toshitsugu Sugimoto; Tatsuya Kobayashi; Toru Yamaguchi; Akiko Kobayashi; Kazuo Chihara
Evaluation of changes in bone density and biochemical parameters after parathyroidectomy in primary hyperparathyroidism.
Endocrine journal 2000;47(3):231-7.
2000: Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Treatment of osteopenia secondary to primary hyperparathyroidism.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2000;54 Suppl 1():104s-107s.
2000: Hidetaka Wakiyama; Toshitsugu Sugimoto; K Ataka; C Yamashita; Yoshihiko Tsuji; Keitaro Nakagiri; K Inoue; Morihito Okada
Intravenous leiomyomatosis extending into the right ventricular cavity: one-stage radical operation using cardiopulmonary bypass--a case report.
Angiology 2000;51(6):505-9.
2000: Michiko Kanzawa; Toshitsugu Sugimoto; Masanori Kanatani; Kazuo Chihara
Involvement of osteoprotegerin/osteoclastogenesis inhibitory factor in the stimulation of osteoclast formation by parathyroid hormone in mouse bone cells.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(6):661-4.
2000: Daiki Nakaoka; Toshitsugu Sugimoto; Tatsuya Kobayashi; Toru Yamaguchi; Akiko Kobayashi; Kazuo Chihara
Prediction of bone mass change after parathyroidectomy in patients with primary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 2000;85(5):1901-7.
2000: Shinichi Matsumoto; Yasuhiro Fujino; Yasuyuki Suzuki; Yasuki Tanioka; S Muramatsu; Toshitsugu Sugimoto; Yonson Ku; Y Yasunami; Yoshikazu Kuroda
Evidence of protein synthesis during resuscitation of ischemically damaged canine pancreas by the two-layer method.
Pancreas 2000;20(4):411-4.
2000: Masanori Kanatani; Toshitsugu Sugimoto; K Nishiyama; Kazuo Chihara
Stimulatory effect of insulin-like growth factor binding protein-5 on mouse osteoclast formation and osteoclastic bone-resorbing activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(5):902-10.
2000: Morihito Okada; Takuro Tsukube; Toshitsugu Sugimoto; C Yamashita; T Tsujino; M Yokoyama
[Transaortic video-assisted thrombectomy in the left ventricular cavity after acute myocardial infarction].
Kyobu geka. The Japanese journal of thoracic surgery 2000;53(2):106-9.
2000: Y Ootaki; Morihito Okada; C Yamashita; Toshitsugu Sugimoto; Hidetaka Wakiyama
Tension hemothorax caused by a ruptured aneurysm of the descending thoracic aorta: report of a a case.
Surgery today 2000;30(6):558-60.
2000: Yoshihisa Morimoto; Toshitsugu Sugimoto; Morihito Okada; T Mukai
Clinical assessment of vascular thrombosis using indium-111 platelet scintigraphy.
Angiology 2000;51(1):61-8.
1999: Toshitsugu Sugimoto; Daiki Nakaoka; M Nasu; Michiko Kanzawa; Takeshi Sugishita; Kazuo Chihara
Effect of recombinant human growth hormone in elderly osteoporotic women.
Clinical endocrinology 1999;51(6):715-24.
1999: Toshitsugu Sugimoto; Morihito Okada; C Yamashita; K Ataka; Masato Yoshida; Y Toyoda; Nobuchika Ozaki
Surgical assessment of tricuspid valve replacement for severe tricuspid regurgitation without stenosis.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 1999;5(5):300-3.
1999: Masato Fukuoka; Morihito Okada; Toshitsugu Sugimoto
Assessment of lower extremity venous function using foot venous pressure measurement.
The British journal of surgery 1999;86(9):1149-54.
1999: Toshitsugu Sugimoto; Morihito Okada; Masato Yoshida; Keitaro Nakagiri
Paramalleolar bypass concomitantly with extended endarterectomy for limb-threatening ischemia: A case report.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 1999;5(4):276-9.
1999: Masanori Kanatani; Toshitsugu Sugimoto; Michiko Kanzawa; Shozo Yano; Kazuo Chihara
High extracellular calcium inhibits osteoclast-like cell formation by directly acting on the calcium-sensing receptor existing in osteoclast precursor cells.
Biochemical and biophysical research communications 1999;261(1):144-8.
1999: K Miyamoto; Toshitsugu Sugimoto; Morihito Okada; S Maeda
Experimental studies on application of small-caliber vascular prosthesis produced by polyurethane.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 1999;5(3):174-81.
1999: Michiko Kanzawa; Toshitsugu Sugimoto; Tatsuya Kobayashi; Akiko Kobayashi; Kazuo Chihara
Parathyroid hormone gene polymorphisms in primary hyperparathyroidism.
Clinical endocrinology 1999;50(5):583-8.
1999: I Kitano; Toshitsugu Sugimoto; Morihito Okada
Quantitative assessment of peripheral occlusive arterial diseases by color duplex sonography and blood endothelin level.
The Kobe journal of medical sciences 1999;45(2):73-83.
1999: T Kawahira; Toshitsugu Sugimoto; Morihito Okada; S Maeda
An experimental study of surgical treatment for lymphedema in rats: A modified Kinmonth procedure and autologous lymph node capsule-venous anastomosis with lymph node transfer.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 1999;5(2):86-93.
1999: Toshitsugu Sugimoto; Morihito Okada; Nobuchika Ozaki; T Hatakeyama; T Kawahira
Long-term evaluation of treatment for functional tricuspid regurgitation with regurgitant volume: characteristic differences based on primary cardiac lesion.
The Journal of thoracic and cardiovascular surgery 1999;117(3):463-71.
1999: N Ozaki; Toshitsugu Sugimoto; Morihito Okada
Assessment of left ventricular function using dobutamine stress echocardiography and myocardial scintigraphy in valvular heart disease.
The Kobe journal of medical sciences 1999;45(1):41-50.
1999: H Oue; Toshitsugu Sugimoto; Morihito Okada
Strategy for prevention of myonephropathic metabolic syndrome (MNMS): comparison of cooling and perfusion.
The Kobe journal of medical sciences 1999;45(1):13-25.
1999: H Minami; Toshitsugu Sugimoto; Morihito Okada
Evaluation of acute aortic dissection by cine-MRI.
The Kobe journal of medical sciences 1999;45(1):1-11.
1999: Morihito Okada; Toshitsugu Sugimoto; Hidehiro Yamamoto
[Surgical strategy for invasive pulmonary and mediastinal tumors requiring superior vena cava reconstruction].
Kyobu geka. The Japanese journal of thoracic surgery 1999;52(1):14-8.
1998: C Yamashita; K Ataka; Masato Yoshida; Toshitsugu Sugimoto; Hidetaka Wakiyama; Morihito Okada
Results of surgical treatment for thoracoabdominal aneurysm using cardiopulmonary bypass under moderate hypothermia and selective visceral artery perfusion.
The Kobe journal of medical sciences 1998;44(5-6):191-7.
1998: Toshitsugu Sugimoto; Morihito Okada; Nobuchika Ozaki; T Kawahira; M Fukuoka
Influence of functional tricuspid regurgitation on right ventricular function.
The Annals of thoracic surgery 1998;66(6):2044-50.
1998: Yonson Ku; Masahiro Tominaga; Takeshi Iwasaki; Takumi Fukumoto; Sanshiro Muramatsu; Nobuya Kusunoki; Toshitsugu Sugimoto; Yasuyuki Suzuki; Yoshikazu Kuroda; Yoichi Saitoh
Efficacy of repeated percutaneous isolated liver chemoperfusion in local control of unresectable hepatocellular carcinoma.
Hepato-gastroenterology 1998;45(24):1961-5.
1998: Hiroshi Sakaue; Wataru Ogawa; Michihiro Matsumoto; Shun'ichi Kuroda; M Takata; Toshitsugu Sugimoto; Bruce M Spiegelman; Masato Kasuga
Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase.
The Journal of biological chemistry 1998;273(44):28945-52.
1998: Hidetaka Wakiyama; Morihito Okada; C Yamashita; K Ataka; Masato Yoshida; Keitaro Nakagiri; Toshitsugu Sugimoto
[Early and late surgical mortality of acute type A aortic dissections by open distal anastomosis with deep hypothermic retrograde cerebral perfusion].
Kyobu geka. The Japanese journal of thoracic surgery 1998;51(8 Suppl):641-6.
1998: Toshitsugu Sugimoto; Daiki Nakaoka; M Nasu; Michiko Kanzawa; Takeshi Sugishita; Kazuo Chihara
Age-dependent changes in body composition in postmenopausal Japanese women: relationship to growth hormone secretion as well as serum levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
European journal of endocrinology / European Federation of Endocrine Societies 1998;138(6):633-9.
1998: Toshitsugu Sugimoto
[Hyperparathyroidism and its management].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(6):1591-7.
1998: Masanori Kanatani; Toshitsugu Sugimoto; Y Takahashi; Hiroshi Kaji; Riko Kitazawa; Kazuo Chihara
Estrogen via the estrogen receptor blocks cAMP-mediated parathyroid hormone (PTH)-stimulated osteoclast formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(5):854-62.
1998: M Nasu; Toshitsugu Sugimoto; Hiroshi Kaji; Junichi Kano; Kazuo Chihara
Carboxyl-terminal parathyroid hormone fragments stimulate type-1 procollagen and insulin-like growth factor-binding protein-5 mRNA expression in osteoblastic UMR-106 cells.
Endocrine journal 1998;45(2):229-34.
1998: Tatsuya Kobayashi; Toshitsugu Sugimoto; Michiko Kanzawa; Kazuo Chihara
Identification of an enhancer sequence in 5'-flanking region of 1A exon of mouse liver/bone/kidney-type alkaline phosphatase gene.
Biochemistry and molecular biology international 1998;44(4):683-91.
1998: Yoshihiko Tsuji; C Yamashita; Hidetaka Wakiyama; Y Toyoda; Masato Yoshida; Toshitsugu Sugimoto; K Ataka; N Ishii; T Shida; Morihito Okada
Surgical treatment for transvenous tumor extension into the heart: four cases.
Journal of vascular surgery 1998;27(4):740-4.
1998: Masato Fukuoka; Morihito Okada; Toshitsugu Sugimoto
Foot venous pressure measurement for evaluation of lower limb venous insufficiency.
Journal of vascular surgery 1998;27(4):671-6.
1998: Yonson Ku; Takeshi Iwasaki; Takumi Fukumoto; Masahiro Tominaga; Sanshiro Muramatsu; Nobuya Kusunoki; Toshitsugu Sugimoto; Yasuyuki Suzuki; Yoshikazu Kuroda; Yoichi Saitoh; M Sako; Shinichi Matsumoto; Shozo Hirota; Hidefumi Obara
Induction of long-term remission in advanced hepatocellular carcinoma with percutaneous isolated liver chemoperfusion.
Annals of surgery 1998;227(4):519-26.
1998: Tatsuya Kobayashi; Toshitsugu Sugimoto; Akiko Kobayashi; Kazuo Chihara
Vitamin D receptor genotype is associated with cortical bone loss in Japanese patients with primary hyperparathyroidism.
Endocrine journal 1998;45(1):123-5.
1998: Toshitsugu Sugimoto; Morihito Okada; C Yamashita; Masato Yoshida; Nobuchika Ozaki
Repeat tricuspid valve replacement for acquired valvular heart disease: report of a case.
Surgery today 1998;28(10):1112-4.
1998: Hidetaka Wakiyama; Morihito Okada; C Yamashita; Keitaro Nakagiri; N Yoshimura; Masato Yoshida; K Ataka; Toshitsugu Sugimoto
Successful surgical treatment of an Edwards type IIIB right aortic arch aneurysm: report of a case.
Surgery today 1998;28(10):1098-101.
1998: Yonson Ku; Takeshi Iwasaki; Takumi Fukumoto; Masahiro Tominaga; Sanshiro Muramatsu; Nobuya Kusunoki; Toshitsugu Sugimoto; Yasuyuki Suzuki; Yoshikazu Kuroda; Yoichi Saitoh
Percutaneous isolated liver chemoperfusion for treatment of unresectable malignant liver tumors: technique, pharmacokinetics, clinical results.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1998;147():67-82.
1997: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; M Fukase; Kazuo Chihara
Cloning of mouse diastrophic dysplasia sulfate transporter gene induced during osteoblast differentiation by bone morphogenetic protein-2.
Gene 1997;198(1-2):341-9.
1997: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; Makiko Fujii; Kazuo Chihara
Cloning and characterization of the 5'-flanking region of the mouse diastrophic dysplasia sulfate transporter gene.
Biochemical and biophysical research communications 1997;238(3):738-43.
1997: Nobuya Kusunoki; Yonson Ku; Masahiro Tominaga; Takeshi Iwasaki; Sanshiro Muramatsu; Toshitsugu Sugimoto; Yoshikazu Kuroda
[Efficacy of combined use of sodium thiosulfate in percutaneous isolated liver chemoperfusion of cisplatin under complete hepatic venous isolated and charcoal hemoperfusion].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(12):1781-4.
1997: Toshitsugu Sugimoto; Yonson Ku; Masahiro Tominaga; Takeshi Iwasaki; Sanshiro Muramatsu; Nobuya Kusunoki; Yoshikazu Kuroda
[A case of multiple colonic liver metastases treated successfully with percutaneous isolated liver chemoperfusion using cisplatin].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(12):1753-6.
1997: Tatsuya Kobayashi; Toshitsugu Sugimoto; Kazuo Chihara
Clinical and biochemical presentation of primary hyperparathyroidism in Kansai district of Japan.
Endocrine journal 1997;44(4):595-601.
1997: Toshitsugu Sugimoto; K Nishiyama; F Kuribayashi; Kazuo Chihara
Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(8):1272-9.
1997: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; K Nishiyama; M Nasu; Kazuo Chihara
Insulin-like growth factor-I mediates osteoclast-like cell formation stimulated by parathyroid hormone.
Journal of cellular physiology 1997;172(1):55-62.
1997: M Nasu; Toshitsugu Sugimoto; Kazuo Chihara
Stimulatory effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 on insulin-like growth factor-binding protein-5 mRNA expression in osteoblastic UMR-106 cells: the difference between transient and continuous treatments.
FEBS letters 1997;409(1):63-6.
1997: M Nasu; Toshitsugu Sugimoto; M Chihara; M Hiraumi; F Kurimoto; Kazuo Chihara
Effect of natural menopause on serum levels of IGF-I and IGF-binding proteins: relationship with bone mineral density and lipid metabolism in perimenopausal women.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(6):608-16.
1997: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; K Nishiyama; Kazuo Chihara
Dexamethasone stimulates osteoclast-like cell formation by directly acting on hemopoietic blast cells and enhances osteoclast-like cell formation stimulated by parathyroid hormone and prostaglandin E2.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(5):734-41.
1997: Yoshihiko Tsuji; A Sasada; Y Watanabe; Toshitsugu Sugimoto; T Ohkubo; Morihito Okada
Hepatectomy of right superior portion (segment VII and VIII) combined with right hepatic vein reconstruction: a case report.
The Kobe journal of medical sciences 1997;43(2):65-9.
1997: Kazuo Chihara; Toshitsugu Sugimoto
The action of GH/IGF-I/IGFBP in osteoblasts and osteoclasts.
Hormone research 1997;48 Suppl 5():45-9.
1996: Toshitsugu Sugimoto; Morihito Okada; M Fukuoka; M Uematsu; M Yoshida; H Toyama
Surgical treatment of refractory venous stasis ulcer due to a severe impairment of calf muscle pump function: evaluation by air plethysmography. A case report.
Angiology 1996;47(12):1167-71.
1996: N Yoshimura; K Ataka; Masato Yoshida; Toshitsugu Sugimoto; C Yamashita; Morihito Okada; S Nakayama; N Ishii
[A case report of closing aortic dissection with cardiac tamponade].
Kyobu geka. The Japanese journal of thoracic surgery 1996;49(11):943-6.
1996: I Maeda; Yonson Ku; Takeshi Iwasaki; Toshitsugu Sugimoto; Nobuya Kusunoki; Yoshikazu Kuroda; Y Saitoh
[A case of advanced cholangiocellular carcinoma treated successfully by percutaneous isolated liver perfusion with cisplatin].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1607-9.
1996: T Kitagawa; Yonson Ku; I Maeda; Takeshi Iwasaki; Nobuya Kusunoki; Toshitsugu Sugimoto; Yoshikazu Kuroda; Y Saitoh
[A case of advanced hepatoma cured by repeated percutaneous isolated liver perfusion using hepatic venous isolation and charcoal hemoperfusion].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1592-5.
1996: Yonson Ku; I Maeda; Masahiro Tominaga; Takeshi Iwasaki; Nobuya Kusunoki; Sanshiro Muramatsu; Toshitsugu Sugimoto; Yoshikazu Kuroda; Y Saitoh
[Evaluation of a single catheter technique for percutaneous isolated liver perfusion].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1502-5.
1996: Takeshi Iwasaki; Yonson Ku; Masahiro Tominaga; I Maeda; Toshitsugu Sugimoto; T Kanamaru; Yoshikazu Kuroda; Y Saitoh
[The effect of high-dose intraarterial chemotherapy with percutaneous hepatic venous isolation and charcoal hemoperfusion (HVI.CHP) for unresectable multiple hepatocellular carcinoma--comparison with other therapeutic modalities].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1426-8.
1996: Nobuya Kusunoki; Yonson Ku; Yusuke Tanigawara; I Maeda; Toshitsugu Sugimoto; Sanshiro Muramatsu; Takeshi Iwasaki; Masahiro Tominaga; Yoshikazu Kuroda; Y Saitoh
[Evaluation of concomitant use of cyclosporin and percutaneous isolated liver perfusion under complete venous isolation and charcoal hemoperfusion].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1408-11.
1996: Hidetaka Wakiyama; Morihito Okada; K Ataka; Toshitsugu Sugimoto
[Successful surgical treatment for distal arch aneurysm involving an aberrant right subclavian artery].
[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 1996;44(8):1155-8.
1996: Morihito Okada; M Okada; N Ishii; C Yamashita; Toshitsugu Sugimoto; Kenji Okada; H Yamagishi; T Yamashita; H Matsuda
Right ventricular ejection fraction in the preoperative risk evaluation of candidates for pulmonary resection.
The Journal of thoracic and cardiovascular surgery 1996;112(2):364-70.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; Kazuo Chihara
High extracellular calcium stimulates osteoclast-like cell formation and bone-resorbing activity in the presence of osteoblastic cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(7):912-20.
1996: Y Toyoda; Morihito Okada; Toshitsugu Sugimoto; Masato Yoshida; K Ataka; C Yamashita
Successful surgical treatment of cardiac cirrhosis. Tricuspid surgery and plasma exchange.
The Journal of cardiovascular surgery 1996;37(3):305-7.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Nasu; Kazuo Chihara
Estrogen blocks parathyroid hormone (PTH)-stimulated osteoclast-like cell formation by selectively affecting PTH-responsive cyclic adenosine monophosphate pathway.
Endocrinology 1996;137(6):2217-24.
1996: Morihito Okada; Toshitsugu Sugimoto
[Tricuspid regurgitation].
Ryōikibetsu shōkōgun shirīzu 1996;(13):374-7.
1996: Morihito Okada; Toshitsugu Sugimoto
[Ruptured chordae tendineae of the tricuspid valve].
Ryōikibetsu shōkōgun shirīzu 1996;(13):371-3.
1996: Morihito Okada; Toshitsugu Sugimoto
[Supravalvular mitral ridge].
Ryōikibetsu shōkōgun shirīzu 1996;(13):221-3.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Prostaglandin E2 stimulates osteoclast-like cell formation and bone-resorbing activity via osteoblasts: role of cAMP-dependent protein kinase.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(1):62-71.
1996: K Nishiyama; Toshitsugu Sugimoto; Hiroshi Kaji; Masanori Kanatani; T Kobayashi; Kazuo Chihara
Stimulatory effect of growth hormone on bone resorption and osteoclast differentiation.
Endocrinology 1996;137(1):35-41.
1995: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; T Kobayashi; K Nishiyama; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(11):1681-90.
1995: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; J Kano; Kazuo Chihara
Effects of 22-oxacalcitriol on bone metabolism in vitro: comparison with calcitriol--effects of 22-oxacalcitriol on osteoclast-like cell formation and bone-resorbing activity.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(5):618-25.
1995: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Kazuo Chihara
Carboxyl-terminal peptides from parathyroid hormone-related protein stimulate osteoclast-like cell formation.
Endocrinology 1995;136(3):842-8.
1995: T Yamaguchi; M Fukase; Toshitsugu Sugimoto; Kazuo Chihara
Hydrolysis of a carboxy-terminal fragment of parathyroid hormone-related protein by rat kidney: evidence for a crucial role of meprin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1995;27(3):131-6.
1995: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Retinoic acid induces osteoclast-like cell formation by directly acting on hemopoietic blast cells and stimulates osteopontin mRNA expression in isolated osteoclasts.
Life sciences 1995;56(22):1903-13.
1995: Toshitsugu Sugimoto; Kazuo Chihara
Signal transduction mechanisms of parathyroid hormone- and parathyroid hormone-related-peptide-stimulated osteoclast-like cell formation from hemopoietic blast cells.
Mineral and electrolyte metabolism 1995;21(1-3):161-5.
1994: Masanori Kanatani; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Role of interleukin-6 and prostaglandins in the effect of monocyte-conditioned medium on osteoclast formation.
The American journal of physiology 1994;267(6 Pt 1):E868-76.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Involvement of protein kinase C in the stimulation of sodium-dependent phosphate transport by parathyroid hormone in osteoblast-like cells.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(6):646-51.
1994: T Yamaguchi; M Fukase; Toshitsugu Sugimoto; H Kido; Kazuo Chihara
Purification of meprin from human kidney and its role in parathyroid hormone degradation.
Biological chemistry Hoppe-Seyler 1994;375(12):821-4.
1994: J Kano; Toshitsugu Sugimoto; Masanori Kanatani; Y Kuroki; T Tsukamoto; M Fukase; Kazuo Chihara
Second messenger signaling of c-fos gene induction by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells: its role in osteoblast proliferation and osteoclast-like cell formation.
Journal of cellular physiology 1994;161(2):358-66.
1994: Hiroshi Kaji; Toshitsugu Sugimoto; A Miyauchi; M Fukase; K Tezuka; Yoshiyuki Hakeda; Masayoshi Kumegawa; Kazuo Chihara
Calcitonin inhibits osteopontin mRNA expression in isolated rabbit osteoclasts.
Endocrinology 1994;135(1):484-7.
1994: Toshitsugu Sugimoto; Masanori Kanatani; J Kano; T Kobayashi; T Yamaguchi; M Fukase; Kazuo Chihara
IGF-I mediates the stimulatory effect of high calcium concentration on osteoblastic cell proliferation.
The American journal of physiology 1994;266(5 Pt 1):E709-16.
1994: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; A Miyauchi; T Kimura; S Sakakibara; M Fukase; Kazuo Chihara
Carboxyl-terminal parathyroid hormone fragments stimulate osteoclast-like cell formation and osteoclastic activity.
Endocrinology 1994;134(4):1897-904.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Biochemical and biophysical research communications 1994;199(3):1216-22.
1994: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; M Fukase; Kazuo Chihara
Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin).
Biochemical and biophysical research communications 1994;199(2):876-80.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Characterization of a chymotrypsin-like hydrolytic activity in the opossum kidney cell.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(3-4):157-62.
1994: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Direct involvement of cAMP-dependent protein kinase in the regulation of alkaline phosphatase activity by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic UMR-106 cells.
Biochemical and biophysical research communications 1994;199(1):271-6.
1994: Toshitsugu Sugimoto; K Ikeda; J Kano; T Yamaguchi; M Fukase; Kazuo Chihara
Cross-talk of parathyroid hormone-responsive dual signal transduction systems in osteoblastic osteosarcoma cells: its role in PTH-induced homologous desensitization of intracellular calcium response.
Journal of cellular physiology 1994;158(2):374-80.
1994: T Yamaguchi; M Fukase; H Kido; Toshitsugu Sugimoto; N Katunuma; Kazuo Chihara
Meprin is predominantly involved in parathyroid hormone degradation by the microvillar membranes of rat kidney.
Life sciences 1994;54(5):381-6.
1993: Toshitsugu Sugimoto; Masanori Kanatani; J Kano; Hiroshi Kaji; T Tsukamoto; T Yamaguchi; M Fukase; Kazuo Chihara
Effects of high calcium concentration on the functions and interactions of osteoblastic cells and monocytes and on the formation of osteoclast-like cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(12):1445-52.
1993: Toshitsugu Sugimoto; J Kano; T Yamaguchi; M Fukase; Kazuo Chihara
Role of calcium/protein kinase C in the regulation of DNA synthesis by parathyroid hormone-related peptide in osteoblastic osteosarcoma cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(12):608-11.
1993: Toshitsugu Sugimoto; Masanori Kanatani; Hiroshi Kaji; T Yamaguchi; M Fukase; Kazuo Chihara
Second messenger signaling of PTH- and PTHRP-stimulated osteoclast-like cell formation from hemopoietic blast cells.
The American journal of physiology 1993;265(3 Pt 1):E367-73.
1993: Hiroshi Kaji; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Role of dual signal transduction systems in the stimulation of bone resorption by parathyroid hormone-related peptide. The direct involvement of cAMP-dependent protein kinase.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(8):421-4.
1993: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Kazuo Chihara
Involvement of dual signal transduction systems in the stimulation of osteoclast-like cell formation by parathyroid hormone and parathyroid hormone-related peptide.
Biochemical and biophysical research communications 1993;194(1):157-62.
1993: Toshitsugu Sugimoto; J Kano; K Ikeda; M Fukase; Kazuo Chihara
Interaction of parathyroid hormone-related peptide-responsive dual signal transduction systems in osteoblastic osteosarcoma cells: role in PTHrP-induced homologous desensitization.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(4):451-8.
1993: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Cross talk of dual-signal transduction systems in the regulation of DNA synthesis by parathyroid hormone in osteoblastic osteosarcoma cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(3):323-9.
1993: Masanori Kanatani; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Effect of 1,25-dihydroxyvitamin D3 on the proliferation of osteoblastic MC3T3-E1 cells by modulating the release of local regulators from monocytes.
Biochemical and biophysical research communications 1993;190(2):529-35.
1992: T Yamaguchi; M Fukase; M Arao; Toshitsugu Sugimoto; Kazuo Chihara
Endothelin 1 hydrolysis by rat kidney membranes.
FEBS letters 1992;309(3):303-6.
1992: Toshitsugu Sugimoto; J Kano; M Fukase; Tsuyoshi Fujita
The participation of the activation of cAMP-dependent protein kinase in cytosolic acidification by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1992;24(9):448-9.
1992: Kenji Okada; T Higami; K Ogawa; T Asada; N Mukohara; M Nishiwaki; Toshitsugu Sugimoto; T Kawamura; M Sakata
[Efficacy of nicorandil on myocardial protection during coronary artery bypass grafting--a comparison with diltiazem].
[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 1992;40(8):1225-32.
1992: Toshitsugu Sugimoto; J Kano; M Fukase; Tsuyoshi Fujita
The activation of cAMP-dependent protein kinase is directly linked to homologous desensitization by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1992;24(7):347-8.
1992: Toshitsugu Sugimoto; J Kano; M Fukase; Tsuyoshi Fujita
Second messenger signaling in the regulation of cytosolic pH and DNA synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells: role of Na+/H+ exchange.
Journal of cellular physiology 1992;152(1):28-34.
1992: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
The direct involvement of cAMP-dependent protein kinase in the regulation of collagen synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblast-like osteosarcoma cells (UMR-106).
Biochemical and biophysical research communications 1992;184(1):525-9.
1992: Y Kuroki; Shunichi Shiozawa; Toshitsugu Sugimoto; Tsuyoshi Fujita
Constitutive expression of c-fos gene inhibits type 1 collagen synthesis in transfected osteoblasts.
Biochemical and biophysical research communications 1992;182(3):1389-94.
1992: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase
The activation of cAMP-dependent protein kinase is directly linked to the stimulation of bone resorption by parathyroid hormone.
Biochemical and biophysical research communications 1992;182(3):1356-61.
1992: K Iwahashi; T Ota; H Sato; H Kanda; Toshitsugu Sugimoto; Morihito Okada; K Nakamura
[Clinical and hemodynamic sequelae of mitral prostheses evaluated by Doppler echocardiography].
Journal of cardiology 1992;22(4):651-9.
1991: Masanori Kanatani; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
Effect of elevated extracellular calcium on the proliferation of osteoblastic MC3T3-E1 cells:its direct and indirect effects via monocytes.
Biochemical and biophysical research communications 1991;181(3):1425-30.
1991: J Kano; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
The activation of cAMP-dependent protein kinase is directly linked to the inhibition of osteoblast proliferation (UMR-106) by parathyroid hormone-related protein.
Biochemical and biophysical research communications 1991;179(1):97-101.
1991: Masanori Kanatani; Toshitsugu Sugimoto; J Kano; M Fukase; Tsuyoshi Fujita
Effect of 17 beta-estradiol on the proliferation of osteoblastic MC3T3-E1 cells via human monocytes.
Biochemical and biophysical research communications 1991;178(3):866-70.
1991: K Ikeda; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
Protein kinase C is involved in PTH-induced homologous desensitization by directly affecting PTH receptor in the osteoblastic osteosarcoma cells.
Endocrinology 1991;128(6):2901-6.
1991: J Kano; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
The activation of cAMP-dependent protein kinase is directly linked to the regulation of osteoblast proliferation (UMR-106) by parathyroid hormone.
Biochemical and biophysical research communications 1991;177(1):365-9.
1991: K Ikeda; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
Role of increase in intracellular calcium in PTH-induced homologous desensitization in UMR-106 cells.
Biochemical and biophysical research communications 1991;176(3):1033-6.
1991: K Ikeda; Toshitsugu Sugimoto; M Fukase; Tsuyoshi Fujita
Phorbol ester induces desensitization of PTH-stimulated cyclic AMP production by decreasing the PTH receptor binding in UMR-106 cells.
Biochemical and biophysical research communications 1991;176(2):764-8.
1990: Toshitsugu Sugimoto; M Miyashita; T Ota; C Yamashita; Morihito Okada; K Nakamura
[Surgical treatment of valvular heart disease associated with Behçet's disease].
[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 1990;38(11):2320-5.
1990: Toshitsugu Sugimoto; K Nakamura; Morihito Okada; T Ota; H Sato; K Iwahashi
New quantitative method for evaluating tricuspid regurgitation.
The Journal of cardiovascular surgery 1990;31(6):778-87.
1990: Toshitsugu Sugimoto; T Ota; H Sato; K Iwahashi; Morihito Okada; K Nakamura
[Characteristic difference of functional tricuspid regurgitation between acquired valvular heart disease and atrial septal defect].
[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai 1990;38(10):2056-62.
1989: T Ohta; H Sato; T Arikawa; K Iwahashi; Toshitsugu Sugimoto; H Kanda; Morihito Okada; K Nakamura
[The influence of left ventricular function on surgical risk in mitral stenosis].
Journal of cardiology 1989;19(3):859-67.
1989: Toshitsugu Sugimoto; M Ota; H Kanda; H Sato; M Nishiwaki; Morihito Okada; K Nakamura
[Selection of surgical procedures for mitral stenosis determined with echocardiography].
Journal of cardiology. Supplement 1989;22():53-4.
1988: Toshitsugu Sugimoto; T Ota; K Nakamura
[A new method quantifying tricuspid regurgitant volume by two-dimensional color and continuous wave Doppler echocardiography].
Journal of cardiology 1988;18(4):1069-81.