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Haruhiko Sugimura

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Japan

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Haruhiko Sugimura
Erratum to: How can research fields be integrated with PET imaging?
Haruhiko Sugimura
How can research fields be integrated with PET imaging?
Haruhiko Sugimura; Hong Tao; Hidetaka Yamada; Moriya Iwaizumi; Kazuya Shinmura; Masako Kasami
[Familial gastric cancer - an update of Japanese cases].

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All Publications

2013: Haruhiko Sugimura
Erratum to: How can research fields be integrated with PET imaging?
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2013;16(2):120.
2013: Haruhiko Sugimura
How can research fields be integrated with PET imaging?
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2013;16(2):118-9.
2013: Haruhiko Sugimura; Hong Tao; Hidetaka Yamada; Moriya Iwaizumi; Kazuya Shinmura; Masako Kasami
[Familial gastric cancer - an update of Japanese cases].
Gan to kagaku ryoho. Cancer & chemotherapy 2013;40(2):154-8.
2013: Haruhiko Sugimura; Satoshi Osawa
Internal frontier: the pathophysiology of the small intestine.
World journal of gastroenterology : WJG 2013;19(2):161-4.
2012: Shinichiro Kiyose; Hiroyuki Konno; Keisuke Konno; Matsuyoshi Maeda; Hiroki Mori; Kiyoko Nagura; Hiroyuki Ogura; Takachika Ozawa; Kazuya Shinmura; Naohiko Hattori; Hideaki Hoshino; Hisaki Igarashi; Takaharu Kamo; Kazunori Kawane; Haruhiko Sugimura
Chromogenic in situ hybridization (CISH) to detect HER2 gene amplification in breast and gastric cancer: comparison with immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH).
Pathology international 2012;62(11):728-34.
2012: Shin-ichiro Kiyose; Nobuya Kurabe; Matsuyoshi Maeda; Kiyoko Nagura; Kazuya Shinmura; Masanori Goto; Naohiko Hattori; Hisaki Igarashi; Tomoaki Kahyo; Masaya Suzuki; Hong Tao; Masaru Tsuboi; Hidetaka Yamada; Haruhiko Sugimura
Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization.
Pathology international 2012;62(7):477-84.
2012: Elakeche Ella; Kazutaka Ikeda; Keiko Ishino; Shinji Kageyama; Nobuya Kurabe; Daisuke Nishizawa; Akiko Nozawa; Chen Renyin; Naomi Sato; Kazuya Shinmura; Fumihiko Tanioka; Hong Tao; Hidetaka Yamada; Haruhiko Sugimura
Association between dopamine beta hydroxylase rs5320 polymorphism and smoking behaviour in elderly Japanese.
Journal of human genetics 2012;57(6):385-90.
2011: T Kahyo; S Matsuura; T Nakamura; Kazuya Shinmura; Y Watanabe; Hidetaka Yamada; Moriya Iwaizumi; Haruhiko Sugimura
A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.
Oncogene 2011;30(44):4453-63.
2011: Kazuya Shinmura; Masaya Suzuki; Hong Tao; Hidetaka Yamada; Masanori Goto; Hisaki Igarashi; Hiroyuki Konno; Matsuyoshi Maeda; Tomonari Matsuda; Shun Matsuura; Haruhiko Sugimura
Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer.
The Journal of pathology 2011;225(3):414-23.
2011: Kazuhito Funai; Toyohiko Morita; Kei Shimizu; Yasumasa Shundo; Haruhiko Sugimura; Norihiko Shiiya
Lymphatic vessel invasion is a significant prognostic indicator in stage IA lung adenocarcinoma.
Annals of surgical oncology 2011;18(10):2968-72.
2011: Kazuya Shinmura; Kazuhito Funai; Masanori Goto; Hisaki Igarashi; Tomonari Matsuda; Shun Matsuura; Hiroshi Niwa; Hiroshi Ogawa; Mari Tajima; Masayuki Tanahashi; Hong Tao; Hidetaka Yamada; Arito Yamane; Haruhiko Sugimura
Aberrant expression and mutation-inducing activity of AID in human lung cancer.
Annals of surgical oncology 2011;18(7):2084-92.
2011: Masafumi Nishino; Naohito Shirai; Mitsushige Sugimoto; Haruhiko Sugimura; Tatsuo Tanaka; Takahiro Uotani; Mihoko Yamade; Akira Hishida; Mutsuhiro Ikuma; Chise Kodaira; Takahisa Furuta
Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers.
Journal of clinical pharmacology 2011;51(7):1079-86.
2011: Tomohiko Setoguchi; Hirotoshi Kikuchi; Masayoshi Yamamoto; Megumi Baba; Manabu Ohta; Kinji Kamiya; Tatsuo Tanaka; Satoshi Baba; Naoko Goto-Inoue; Mitsutoshi Setou; Takeshi Sasaki; Hiroki Mori; Haruhiko Sugimura; Hiroyuki Konno
Microarray analysis identifies versican and CD9 as potent prognostic markers in gastric gastrointestinal stromal tumors.
Cancer science 2011;102(4):883-9.
2011: Haruhiko Sugimura; Hong Tao; Masaya Suzuki; Hiroki Mori; Masaru Tsuboi; Shun Matsuura; Masanori Goto; Kazuya Shinmura; Takachika Ozawa; Fumihiko Tanioka; Naomi Sato; Yoshitaka Matsushima; Shinji Kageyama; Kazuhito Funai; Pei-Hsin Chou; Tomonari Matsuda
Genetic susceptibility to lung cancer.
Frontiers in bioscience (Scholar edition) 2011;3():1463-77.
2011: Kazuya Shinmura; Hong Tao; Kiyoko Nagura; Masanori Goto; Shun Matsuura; Takahiro Mochizuki; Kazuya Suzuki; Masayuki Tanahashi; Hiroshi Niwa; Hiroshi Ogawa; Haruhiko Sugimura
Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma.
Lung cancer (Amsterdam, Netherlands) 2011;71(1):19-27.
2010: Haruhiko Sugimura; Jian-Dong Wang; Hiroki Mori; Masaru Tsuboi; Kiyoko Nagura; Hisaki Igarashi; Hong Tao; Ritsuko Nakamura; Hiroko Natsume; Tomoaki Kahyo; Kazuya Shinmura; Hiroyuki Konno; Yasushi Hamaya; Shigeru Kanaoka; Hideki Kataoka; Xiao-Jun Zhou
EPH-EPHRIN in human gastrointestinal cancers.
World journal of gastrointestinal oncology 2010;2(12):421-8.
2010: Masanori Goto; Kazuya Shinmura; Yusaku Nakabeppu; Hong Tao; Hidetaka Yamada; Toshihiro Tsuneyoshi; Haruhiko Sugimura
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
Human mutation 2010;31(11):E1861-74.
2010: Naomi Sato; Shinji Kageyama; Renyin Chen; Masaya Suzuki; Fumihiko Tanioka; Takaharu Kamo; Kazuya Shinmura; Akiko Nozawa; Haruhiko Sugimura
Association between neurexin 1 (NRXN1) polymorphisms and the smoking behavior of elderly Japanese.
Psychiatric genetics 2010;20(3):135-6.
2010: Masafumi Nishino; Mitsushige Sugimoto; Chise Kodaira; Mihoko Yamade; Naohito Shirai; Mutsuhiro Ikuma; Tatsuo Tanaka; Haruhiko Sugimura; Akira Hishida; Takahisa Furuta
Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers.
Digestive diseases and sciences 2010;55(6):1627-36.
2010: Masaru Tsuboi; Hiroki Mori; Tomoyasu Bunai; Shinji Kageyama; Masaya Suzuki; Koji Okudela; Kazuya Takamochi; Hiroshi Ogawa; Hiroshi Niwa; Kazuya Shinmura; Haruhiko Sugimura
Secreted form of EphA7 in lung cancer.
International journal of oncology 2010;36(3):635-40.
2010: Hong Tao; Kazuya Shinmura; Hidetaka Yamada; Masato Maekawa; Satoshi Osawa; Yasuhiro Takayanagi; Kazuya Okamoto; Tomohiro Terai; Hiroki Mori; Toshio Nakamura; Haruhiko Sugimura
Identification of 5 novel germline APC mutations and characterization of clinical phenotypes in Japanese patients with classical and attenuated familial adenomatous polyposis.
BMC research notes 2010;3():305.
2010: Yoshifumi Morita; Koji Ikegami; Naoko Goto-Inoue; Takahiro Hayasaka; Nobuhiro Zaima; Hiroki Tanaka; Takashi Uehara; Tomohiko Setoguchi; Takanori Sakaguchi; Hisashi Igarashi; Haruhiko Sugimura; Mitsutoshi Setou; Hiroyuki Konno
Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.
Cancer science 2010;101(1):267-73.
2009: Toshiki Matsuura; Kazuhiro Sugihara; Yasuhiro Kohmura; Haruhiko Sugimura; Naohiro Kanayama
Rare form of extraovarian peritoneal serous papillary carcinoma with solitary tumor in the abdominal wall: a case report and literature review.
The journal of obstetrics and gynaecology research 2009;35(6):1142-7.
2009: Hidetaka Yamada; Kazuya Shinmura; Yasuhiro Yamamura; Kiyotaka Kurachi; Toshio Nakamura; Toshihiro Tsuneyoshi; Naoki Yokota; Masato Maekawa; Haruhiko Sugimura
Identification and characterization of a novel germline p53 mutation in a patient with glioblastoma and colon cancer.
International journal of cancer. Journal international du cancer 2009;125(4):973-6.
2009: Masanori Goto; Kazuya Shinmura; Hisaki Igarashi; Minatsu Kobayashi; Hiroyuki Konno; Hidetaka Yamada; Moriya Iwaizumi; Shinji Kageyama; Toshihiro Tsuneyoshi; Shoichiro Tsugane; Haruhiko Sugimura
Altered expression of the human base excision repair gene NTH1 in gastric cancer.
Carcinogenesis 2009;30(8):1345-52.
2009: Tetsunari Takai; Shigeru Kanaoka; Ken-ichi Yoshida; Yasushi Hamaya; Mutsuhiro Ikuma; Naoyuki Miura; Haruhiko Sugimura; Masayoshi Kajimura; Akira Hishida
Fecal cyclooxygenase 2 plus matrix metalloproteinase 7 mRNA assays as a marker for colorectal cancer screening.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(6):1888-93.
2009: Masaya Suzuki; Kiyoko Nagura; Hisaki Igarashi; Hong Tao; Yutaka Midorikawa; Yasuhiko Kitayama; Haruhiko Sugimura
Copy number estimation algorithms and fluorescence in situ hybridization to describe copy number alterations in human tumors.
Pathology international 2009;59(4):218-28.
2009: M Iwaizumi; Kazuya Shinmura; H Mori; H Yamada; Masaya Suzuki; Yasuhiko Kitayama; Hisaki Igarashi; T Nakamura; H Suzuki; Y Watanabe; A Hishida; M Ikuma; Haruhiko Sugimura
Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer.
Gut 2009;58(2):249-60.
2009: Hidetaka Yamada; Kazuya Shinmura; Masanori Goto; Moriya Iwaizumi; Hiroyuki Konno; Hideki Kataoka; Masami Yamada; Takachika Ozawa; Toshihiro Tsuneyoshi; Fumihiko Tanioka; Haruhiko Sugimura
Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients.
Molecular cancer 2009;8():63.
2008: Kazuya Shinmura; Masaya Suzuki; Hidetaka Yamada; Hong Tao; Masanori Goto; Takaharu Kamo; Kiyoko Nagura; Shinji Kageyama; Motohiro Kato; Seishi Ogawa; Masato Maekawa; Kazuya Takamochi; Kazuya Suzuki; Toshio Nakamura; Haruhiko Sugimura
Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient.
Pathology international 2008;58(11):706-12.
2008: Kazuya Shinmura; M Iwaizumi; Hisaki Igarashi; Kiyoko Nagura; H Yamada; Masaya Suzuki; K Fukasawa; Haruhiko Sugimura
Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE).
The Journal of pathology 2008;216(3):365-74.
2008: Masaya Suzuki; Shinji Kageyama; Kazuya Shinmura; Koji Okudela; Tomoyasu Bunai; Kiyoko Nagura; Hisaki Igarashi; Shinichiro Kiyose; Hiroki Mori; Hong Tao; Masanori Goto; Kazuya Takamochi; Takahiro Mochizuki; Kazuya Suzuki; Riuko Ohashi; Hiroshi Ogawa; Takeshi Yamada; Hiroshi Niwa; Toshihiro Tsuneyoshi; Haruhiko Sugimura
Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma.
Journal of surgical oncology 2008;98(6):457-61.
2008: Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Chise Kodaira; Masafumi Nishino; Mihoko Yamade; Mutsuhiro Ikuma; Haruhiko Sugimura; Takashi Ishizaki; Akira Hishida
MDR1 C3435T polymorphism has no influence on developing Helicobacter pylori infection-related gastric cancer and peptic ulcer in Japanese.
Life sciences 2008;83(7-8):301-4.
2008: Masanori Goto; Kazuya Shinmura; Hidetaka Yamada; Toshihiro Tsuneyoshi; Haruhiko Sugimura
OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2'-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa.
Journal of genetics 2008;87(2):181-6.
2008: Hiroki Mori; Masao Nagata; Nariaki Nishijima; Kiyoko Nagura; Hisaki Igarashi; Minoru Hamazaki; Seiichiro Ozono; Haruhiko Sugimura
Malignant pheochromocytoma in a young adult forming the structure simulating Homer Wright rosette: differentiation from neuroblastoma on repeating fluorescence in situ hybridization.
Pathology international 2008;58(8):518-23.
2008: Yoshifumi Arai; Takashi Tsuchida; Fumihiko Tanioka; Haruhiko Sugimura; Chieko Watanabe; Teruaki Hongo; Yoshihiro Tsutsui
Congenital anaplastic astrocytoma differentiated into pilocytic astrocytoma: an autopsy case.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(4):433-9.
2008: Kazuya Shinmura; Shinji Kageyama; Hong Tao; Tomoyasu Bunai; Masaya Suzuki; Takaharu Kamo; Kazuya Takamochi; Kazuya Suzuki; Masayuki Tanahashi; Hiroshi Niwa; Hiroshi Ogawa; Haruhiko Sugimura
EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas.
Lung cancer (Amsterdam, Netherlands) 2008;61(2):163-9.
2008: Haruhiko Sugimura
[Familial aggregation of gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2008;35(4):551-6.
2008: Shinji Kageyama; Kazuya Shinmura; Hiroko Yamamoto; Masanori Goto; Koichi Suzuki; Fumihiko Tanioka; Toshihiro Tsuneyoshi; Haruhiko Sugimura
Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status.
Japanese journal of clinical oncology 2008;38(4):317-22.
2008: Haruhiko Sugimura
Detection of chromosome changes in pathology archives: an application of microwave-assisted fluorescence in situ hybridization to human carcinogenesis studies.
Carcinogenesis 2008;29(4):681-7.
2008: Hong Tao; Kazuya Shinmura; Masaya Suzuki; Suminori Kono; Ryuichi Mibu; Masao Tanaka; Yoshihiro Kakeji; Yoshihiko Maehara; Takeshi Okamura; Koji Ikejiri; Kitaroh Futami; Yohichi Yasunami; Takafumi Maekawa; Kenji Takenaka; Hitoshi Ichimiya; Nobutoshi Imaizumi; Haruhiko Sugimura
Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population.
Cancer science 2008;99(2):355-60.
2008: Mitsushige Sugimoto; Takahisa Furuta; Chise Kodaira; Masafumi Nishino; Mihoko Yamade; Mutsuhiro Ikuma; Haruhiko Sugimura; Akira Hishida
Polymorphisms of matrix metalloproteinase-7 and chymase are associated with susceptibility to and progression of gastric cancer in Japan.
Journal of gastroenterology 2008;43(10):751-61.
2008: Atsushi Suzuki; Shohachi Suzuki; Takanori Sakaguchi; Kosuke Oishi; Kazuhiko Fukumoto; Shigeyasu Ota; Keisuke Inaba; Yasuo Takehara; Haruhiko Sugimura; Takashi Uchiyama; Hiroyuki Konno
Colonic fistula associated with severe acute pancreatitis: report of two cases.
Surgery today 2008;38(2):178-83.
2007: Yoshihisa Watanabe; Kiyoshi Shibata; Haruhiko Sugimura; Masato Maekawa
p53-dependent change in replication timing of the human genome.
Biochemical and biophysical research communications 2007;364(2):289-93.
2007: Hidetaka Yamada; Kazuya Shinmura; Shinobu Ikeda; Hong Tao; Tetsuya Otani; Tomoyuki Hanaoka; Toshihiro Tsuneyoshi; Shoichiro Tsugane; Haruhiko Sugimura
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
Scandinavian journal of gastroenterology 2007;42(12):1479-85.
2007: Hirotoshi Kikuchi; Masayoshi Yamamoto; Yoshihiro Hiramatsu; Megumi Baba; Manabu Ohta; Kinji Kamiya; Tatsuo Tanaka; Shohachi Suzuki; Haruhiko Sugimura; Masatoshi Kitagawa; Toshikazu Kanai; Yasuhiko Kitayama; Tatsuo Kanda; Ken Nishikura; Hiroyuki Konno
Effect of loss of heterozygosity of the c-kit gene on prognosis after hepatectomy for metastatic liver gastrointestinal stromal tumors.
Cancer science 2007;98(11):1734-9.
2007: Koji Okudela; Masaya Suzuki; Shinji Kageyama; Tomoyasu Bunai; Kiyoko Nagura; Hisaki Igarashi; Kazuya Takamochi; Kazuya Suzuki; Takeshi Yamada; Hiroshi Niwa; Riuko Ohashi; Hiroshi Ogawa; Hiroki Mori; Hitoshi Kitamura; Takeshi Kaneko; Toshihiro Tsuneyoshi; Haruhiko Sugimura
PIK3CA mutation and amplification in human lung cancer.
Pathology international 2007;57(10):664-71.
2007: Kazuya Takamochi; Kazuya Suzuki; Haruhiko Sugimura; Kazuhito Funai; Hiroki Mori; Abul Hasan Muhammad Bashar; Teruhisa Kazui
Surgical resection after gefitinib treatment in patients with lung adenocarcinoma harboring epidermal growth factor receptor gene mutation.
Lung cancer (Amsterdam, Netherlands) 2007;58(1):149-55.
2007: Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Akiko Nakamura; Masayoshi Kajimura; Haruhiko Sugimura; Akira Hishida
Effects of interleukin-10 gene polymorphism on the development of gastric cancer and peptic ulcer in Japanese subjects.
Journal of gastroenterology and hepatology 2007;22(9):1443-9.
2007: Hidetaka Yamada; Kazuya Shinmura; Koji Okudela; Masanori Goto; Masaya Suzuki; Ken Kuriki; Toshihiro Tsuneyoshi; Haruhiko Sugimura
Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.
Carcinogenesis 2007;28(9):2013-8.
2007: Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Chise Kodaira; Masafumi Nishino; Mutsuhiro Ikuma; Haruhiko Sugimura; Akira Hishida
Role of angiotensinogen gene polymorphism on Helicobacter pylori infection-related gastric cancer risk in Japanese.
Carcinogenesis 2007;28(9):2036-40.
2007: Hiroyuki Suzuki; Haruhiko Sugimura; Kenji Hashimoto
Overexpression of heat shock protein 27 is associated with good prognosis in the patient with oral squamous cell carcinoma.
The British journal of oral & maxillofacial surgery 2007;45(2):123-9.
2007: Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Akiko Nakamura; Fang Xiao; Masayoshi Kajimura; Haruhiko Sugimura; Akira Hishida
Different effects of polymorphisms of tumor necrosis factor-alpha and interleukin-1 beta on development of peptic ulcer and gastric cancer.
Journal of gastroenterology and hepatology 2007;22(1):51-9.
2006: Hiroyuki Suzuki; Haruhiko Sugimura; Kenji Hashimoto
p16INK4A in oral squamous cell carcinomas--a correlation with biological behaviors: immunohistochemical and FISH analysis.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2006;64(11):1617-23.
2006: Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Mutsuhiro Ikuma; Haruhiko Sugimura; Akira Hishida
Influences of chymase and angiotensin I-converting enzyme gene polymorphisms on gastric cancer risks in Japan.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(10):1929-34.
2006: Hirotoshi Kikuchi; Masayoshi Yamamoto; Yoshihiro Hiramatsu; Megumi Baba; Manabu Ohta; Kinji Kamiya; Tatsuo Tanaka; Shohachi Suzuki; Haruhiko Sugimura; Hiroyuki Konno
[Manifestation of liver metastasis 13 years after gastrectomy for gastric GIST].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2006;103(9):1055-60.
2006: Yasuhiko Kitayama; Hisaki Igarashi; Taeko Kozu; Kiyoko Nagura; Yohei Ohashi; Haruhiko Sugimura
Repeated fluorescence in situ hybridization by a microwave-enhanced protocol.
Pathology international 2006;56(9):490-3.
2006: Takehisa Sano; Yasuhiko Kitayama; Hisaki Igarashi; Masaya Suzuki; Fumihiko Tanioka; Kingo Chida; Koji Okudela; Haruhiko Sugimura
Chromosomal numerical abnormalities in early stage lung adenocarcinoma.
Pathology international 2006;56(3):117-25.
2006: Kimihiro Yamashita; Hisaki Igarashi; Yasuhiko Kitayama; Takachika Ozawa; Shinichiro Kiyose; Hiroyuki Konno; Teruhisa Kazui; Shumpei Ishikawa; Hiroyuki Aburatani; Fumihiko Tanioka; Masaya Suzuki; Haruhiko Sugimura
Chromosomal numerical abnormality profiles of gastrointestinal stromal tumors.
Japanese journal of clinical oncology 2006;36(2):85-92.
2006: Hirotoshi Kikuchi; Kimihiro Yamashita; Toshiki Kawabata; Masayoshi Yamamoto; Yoshihiro Hiramatsu; Kenji Kondo; Megumi Baba; Manabu Ohta; Kinji Kamiya; Tatsuo Tanaka; Shohachi Suzuki; Kyoko Kitagawa; Masatoshi Kitagawa; Haruhiko Sugimura; Hiroyuki Konno
Immunohistochemical and genetic features of gastric and metastatic liver gastrointestinal stromal tumors: sequential analyses.
Cancer science 2006;97(2):127-32.
2005: Hisaki Igarashi; Kimihiro Yamashita; Masaya Suzuki; Yasuhiko Kitayama; Jun Isogaki; Keiji Maruyama; Ken-Ichi Sunayama; Hitoshi Tsuda; Takachika Ozawa; Shinichiro Kiyose; Haruhiko Sugimura
Simultaneous imaging of membrane antigen and the corresponding chromosomal locus in pathology archives.
Pathology international 2005;55(12):753-6.
2005: Jiandong Wang; Hideki Kataoka; Masaya Suzuki; Naomi Sato; Ritsuko Nakamura; Hong Tao; Keiji Maruyama; Jun Isogaki; Shigeru Kanaoka; Megumi Ihara; Masamitsu Tanaka; Masao Kanamori; Toshio Nakamura; Kazuya Shinmura; Haruhiko Sugimura
Downregulation of EphA7 by hypermethylation in colorectal cancer.
Oncogene 2005;24(36):5637-47.
2005: Hidetaka Yamada; Kazuya Shinmura; Toshihiro Tsuneyoshi; Haruhiko Sugimura
Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression.
Journal of genetics 2005;84(2):131-6.
2005: Masato Maekawa; Terumi Taniguchi; Takeshi Uramoto; Hitomi Higashi; Toshinobu Horii; Akihiro Takeshita; Haruhiko Sugimura; Masao Kanamori
Pilot study of arbitrarily primed PCR-single stranded DNA conformation polymorphism analysis for screening genetic polymorphisms related to specific phenotypes.
Clinica chimica acta; international journal of clinical chemistry 2005;355(1-2):181-4.
2005: Ritsuko Nakamura; Hideki Kataoka; Naomi Sato; Masao Kanamori; Megumi Ihara; Hisaki Igarashi; Sanjar Ravshanov; You-Jie Wang; Zhong-You Li; Takahiro Shimamura; Toshihiko Kobayashi; Hiroyuki Konno; Kazuya Shinmura; Masamitsu Tanaka; Haruhiko Sugimura
EPHA2/EFNA1 expression in human gastric cancer.
Cancer science 2005;96(1):42-7.
2005: Kazuya Shinmura; Masanori Goto; Hong Tao; S Shimizu; Y Otsuki; H Kobayashi; S Ushida; K Suzuki; Toshihiro Tsuneyoshi; Haruhiko Sugimura
A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.
Clinical genetics 2005;67(1):81-6.
2004: Kazuya Shinmura; Hong Tao; Masanori Goto; Hisaki Igarashi; Terumi Taniguchi; Masato Maekawa; Toshiro Takezaki; Haruhiko Sugimura
Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer.
Carcinogenesis 2004;25(12):2311-7.
2004: Yoshihisa Watanabe; Toshimichi Ikemura; Haruhiko Sugimura
Amplicons on human chromosome 11q are located in the early/late-switch regions of replication timing.
Genomics 2004;84(5):796-805.
2004: Hirotoshi Kikuchi; Hiroyuki Konn; Kinji Kamiya; Megumi Baba; Manabu Ohta; Kenji Kondo; Yoshihiro Hiramatsu; Masayoshi Yamamoto; Tatsuo Tanaka; Haruhiko Sugimura; Manabu Ohashi; Tatsuo Kanda; Satoshi Nakamura
[Two cases of postoperative recurrence of gastric GIST treated by imatinib].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(10):1569-73.
2004: Hong Tao; Kazuya Shinmura; Tomoyuki Hanaoka; Syusuke Natsukawa; Kozo Shaura; Yoichi Koizumi; Yoshio Kasuga; Takachika Ozawa; Toshimasa Tsujinaka; Zhongyou Li; Satoru Yamaguchi; Jun Yokota; Haruhiko Sugimura; Shoichiro Tsugane
A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.
Carcinogenesis 2004;25(10):1859-66.
2004: Kazuya Shinmura; Hong Tao; Hidetaka Yamada; Hideki Kataoka; Ravshanov Sanjar; Jiandong Wang; Kimio Yoshimura; Haruhiko Sugimura
Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Human mutation 2004;24(3):273-4.
2004: Yoshihiro Hiramatsu; Hiroyuki Konno; Kinji Kamiya; Megumi Baba; Manabu Ohta; Kenji Kondo; Masayoshi Yamamoto; Hirotoshi Kikuchi; Tatsuo Tanaka; Haruhiko Sugimura; Satoshi Nakamura
[A case of gastric GIST treated preoperatively by imatinib mesylate].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(8):1219-23.
2004: Shigeru Kanaoka; Ken-Ichi Yoshida; Naoyuki Miura; Haruhiko Sugimura; Masayoshi Kajimura
Potential usefulness of detecting cyclooxygenase 2 messenger RNA in feces for colorectal cancer screening.
Gastroenterology 2004;127(2):422-7.
2004: Masato Maekawa; Tomonori Nagaoka; Terumi Taniguchi; Hitomi Higashi; Haruhiko Sugimura; Kokichi Sugano; Hiroyuki Yonekawa; Takatomo Satoh; Toshinobu Horii; Naohito Shirai; Akihiro Takeshita; Takashi Kanno
Three-dimensional microarray compared with PCR-single-strand conformation polymorphism analysis/DNA sequencing for mutation analysis of K-ras codons 12 and 13.
Clinical chemistry 2004;50(8):1322-7.
2004: Keiko Kobayashi; Michiho Nishioka; Takashi Kohno; Masaki Nakamoto; Arafumi Maeshima; Kazuhiko Aoyagi; Hiroki Sasaki; Seiichi Takenoshita; Haruhiko Sugimura; Jun Yokota
Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo.
Oncogene 2004;23(17):3089-96.
2004: Masamitsu Tanaka; Riuko Ohashi; Ritsuko Nakamura; Kazuya Shinmura; Takaharu Kamo; Ryuichi Sakai; Haruhiko Sugimura
Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2.
The EMBO journal 2004;23(5):1075-88.
2004: Hideki Kataoka; Hisaki Igarashi; Masao Kanamori; Megumi Ihara; Jian-Dong Wang; You-Jie Wang; Zhong-You Li; Takahiro Shimamura; Toshihiko Kobayashi; Keiji Maruyama; Toshio Nakamura; Hajime Arai; Masayoshi Kajimura; Hiroyuki Hanai; Masamitsu Tanaka; Haruhiko Sugimura
Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer.
Cancer science 2004;95(2):136-41.
2004: Takahisa Furuta; Naohito Shirai; Fang Xiao; Emad M El-Omar; Charles S Rabkin; Haruhiko Sugimura; Takashi Ishizaki; Kyoichi Ohashi
Polymorphism of interleukin-1beta affects the eradication rates of Helicobacter pylori by triple therapy.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(1):22-30.
2003: Zhongyou Li; Masamitsu Tanaka; Hideki Kataoka; Ritsuko Nakamura; Ravshanov Sanjar; Kazuya Shinmura; Haruhiko Sugimura
EphA2 up-regulation induced by deoxycholic acid in human colon carcinoma cells, an involvement of extracellular signal-regulated kinase and p53-independence.
Journal of cancer research and clinical oncology 2003;129(12):703-8.
2003: Ritsuko Nakamura; Jian-Ping Song; Jun Isogaki; Yasuhiko Kitayama; Haruhiko Sugimura
Multiple (multicentric and multifocal) cancers in the ipsilateral breast with different histologies: profiles of chromosomal numerical abnormality.
Japanese journal of clinical oncology 2003;33(9):463-9.
2003: Ritsuko Nakamura; Haruhiko Sugimura
[Molecular biology of colorectal cancer: The cell cycle and its regulation].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():91-4.
2003: Yasuhiko Kitayama; Hisaki Igarashi; Fumitoshi Watanabe; Yasuhiko Maruyama; Masao Kanamori; Haruhiko Sugimura
Nonrandom chromosomal numerical abnormality predicting prognosis of gastric cancer: a retrospective study of 51 cases using pathology archives.
Laboratory investigation; a journal of technical methods and pathology 2003;83(9):1311-20.
2003: Masato Maekawa; Terumi Taniguchi; Jinko Ishikawa; Haruhiko Sugimura; Kokichi Sugano; Takashi Kanno
Promoter hypermethylation in cancer silences LDHB, eliminating lactate dehydrogenase isoenzymes 1-4.
Clinical chemistry 2003;49(9):1518-20.
2003: Kotaro Tozawa; Hiroyuki Hanai; Ken Sugimoto; Satoshi Baba; Haruhiko Sugimura; Taiki Aoshi; Masato Uchijima; Toshi Nagata; Yukio Koide
Evidence for the critical role of interleukin-12 but not interferon-gamma in the pathogenesis of experimental colitis in mice.
Journal of gastroenterology and hepatology 2003;18(5):578-87.
2003: Masato Maekawa; Terumi Taniguchi; Chika Tatebayashi; Toshinobu Horii; Akihiro Takeshita; Haruhiko Sugimura; Kokichi Sugano; Hiroyuki Yonekawa; Tomonori Nagaoka; Takashi Kanno
[Basic studies on mutation analysis of K-ras codon 12 by use of three-dimensional microarray system].
Rinsho byori. The Japanese journal of clinical pathology 2003;51(4):306-12.
2003: Masamitsu Tanaka; Takaharu Kamo; Satoshi Ota; Haruhiko Sugimura
Association of Dishevelled with Eph tyrosine kinase receptor and ephrin mediates cell repulsion.
The EMBO journal 2003;22(4):847-58.
2003: Yoshiro Otsuki; Masamitsu Tanaka; Takaharu Kamo; Chifumi Kitanaka; Yoshiyuki Kuchino; Haruhiko Sugimura
Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts.
The Journal of biological chemistry 2003;278(7):5132-40.
2003: Ying Wang; Jian-Ping Song; Masami Ikeda; Kazuya Shinmura; Jun Yokota; Haruhiko Sugimura
Ile-Leu substitution (I415L) in germline E-cadherin gene (CDH1) in Japanese familial gastric cancer.
Japanese journal of clinical oncology 2003;33(1):17-20.
2002: Jian-Ping Song; Yasuhiko Kitayama; Hisaki Igarashi; Rong-Jun Guo; You-Jie Wang; Toshihiko Kobayashi; Hiroyuki Konno; Hideki Kataoka; Masamitsu Tanaka; Haruhiko Sugimura
Centromere numerical abnormality in the papillary, papillotubular type of early gastric cancer, a further characterization of a subset of gastric cancer.
International journal of oncology 2002;21(6):1205-11.
2002: You jie Wang; Satoshi Ota; Hideki Kataoka; Masao Kanamori; Zhong you Li; Hamid Band; Masamitsu Tanaka; Haruhiko Sugimura
Negative regulation of EphA2 receptor by Cbl.
Biochemical and biophysical research communications 2002;296(1):214-20.
2002: noriaki sunaga; Takashi Kohno; Noriko Yanagitani; Haruhiko Sugimura; Hideo Kunitoh; Tomohide Tamura; Yoshikazu Takei; Satoshi Tsuchiya; Ryusei Saito; Jun Yokota
Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(8):730-8.
2002: Hideki Kataoka; Masamitsu Tanaka; Masao Kanamori; Shigeto Yoshii; Megumi Ihara; You-Jie Wang; Jian-Ping Song; Zhong-You Li; Hajime Arai; Yoshiro Otsuki; Toshihiko Kobayashi; Hiroyuki Konno; Hiroyuki Hanai; Haruhiko Sugimura
Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer.
Journal of cancer research and clinical oncology 2002;128(7):343-8.
2002: Takahisa Furuta; Emad M El-Omar; Fang Xiao; Naohito Shirai; Misako Takashima; Haruhiko Sugimura; Haruhiko Sugimurra
Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan.
Gastroenterology 2002;123(1):92-105.
2002: Zhong you Li; You jie Wang; Jian ping Song; Hideki Kataoka; Shigeto Yoshii; Chang ming Gao; Ya ping Wang; Jian nong Zhou; Satoshi Ota; Masamitsu Tanaka; Haruhiko Sugimura
Genomic structure of the human beta-PIX gene and its alteration in gastric cancer.
Cancer letters 2002;177(2):203-8.
2002: Takahisa Furuta; Naohito Shirai; Misako Takashima; Fang Xiao; Haruhiko Sugimura
Effect of genotypic differences in interleukin-1 beta on gastric acid secretion in Japanese patients infected with Helicobacter pylori.
The American journal of medicine 2002;112(2):141-3.
2002: Manabu Ohta; Hiroyuki Konno; Tatsuo Tanaka; Megumi Baba; Kinji Kamiya; Hiroshi Mitsuoka; Naoki Unno; Haruhiko Sugimura; Satoshi Nakamura
Gastrojejunocolic fistula after gastrectomy with Billroth II reconstruction: report of a case.
Surgery today 2002;32(4):367-70.
2002: Toshio Nakamura; Keiji Maruyama; Hidefumi Kashiwabara; Kenichi Sunayama; Kou Ohata; Atsuko Fukazawa; Kazuhiko Yasumi; Haruhiko Sugimura; Satoshi Nakamura
Diverticulitis causing a high serum level of carbohydrate antigen 19-9: report of a case.
Surgery today 2002;32(3):282-4.
2002: Toshihiko Kobayashi; Haruhiko Sugimura; Taizo Kimura
Total gastrectomy is not always necessary for advanced gastric cancer of the cardia.
Digestive surgery 2002;19(1):15-21.
2001: T Nakamura; T Ozawa; T Kawasaki; H Nakamura; Haruhiko Sugimura
Glucose-6-phosphatase gene mutations in 20 adult Japanese patients with glycogen storage disease type 1a with reference to hepatic tumors.
Journal of gastroenterology and hepatology 2001;16(12):1402-8.
2001: Shigeto Yoshii; Masamitsu Tanaka; Yoshiro Otsuki; T Fujiyama; Hideki Kataoka; Hajime Arai; Hiroyuki Hanai; Haruhiko Sugimura
Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene.
Molecular and cellular biology 2001;21(20):6796-807.
2001: Akira Endoh; Noriko Inoue; T Katoh; T Nakamura; Haruhiko Sugimura; Takehiko Ohzeki
A case of glycogen storage disease IA with multiple hepatic tumors managed by transcatheter arterial embolization and an acarbose diet.
Journal of pediatric gastroenterology and nutrition 2001;33(3):333-6.
2001: Megumi Baba; Hiroyuki Konno; Tatsuo Tanaka; K Kamiya; Satoshi Baba; Haruhiko Sugimura; Satoshi Nakamura
Relationship of p53 and Helicobacter pylori to clinicopathological features of human remnant stomach cancer after gastric surgery for primary gastric cancer.
Oncology reports 2001;8(4):831-4.
2001: Takahisa Furuta; Naohito Shirai; Misako Takashima; Fang Xiao; Hiroyuki Hanai; K Nakagawa; Haruhiko Sugimura; Kyoichi Ohashi; Takashi Ishizaki
Effects of genotypic differences in CYP2C19 status on cure rates for Helicobacter pylori infection by dual therapy with rabeprazole plus amoxicillin.
Pharmacogenetics 2001;11(4):341-8.
2001: Misako Takashima; Takahisa Furuta; Hiroyuki Hanai; Haruhiko Sugimura; Eizo Kaneko
Effects of Helicobacter pylori infection on gastric acid secretion and serum gastrin levels in Mongolian gerbils.
Gut 2001;48(6):765-73.
2001: Yoshiro Otsuki; Masamitsu Tanaka; Shigeto Yoshii; N Kawazoe; K Nakaya; Haruhiko Sugimura
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4385-90.
2001: Rong-Jun Guo; Hajime Arai; Yasuhiko Kitayama; Hisaki Igarashi; H Hemmi; T Arai; Hiroyuki Hanai; Haruhiko Sugimura
Microsatellite instability of papillary subtype of human gastric adenocarcinoma and hMLH1 promoter hypermethylation in the surrounding mucosa.
Pathology international 2001;51(4):240-7.
2001: S M Oba; You-Jie Wang; Jian-Ping Song; Zhong-You Li; K Kobayashi; Shoichiro Tsugane; G S Hamada; Masamitsu Tanaka; Haruhiko Sugimura
Genomic structure and loss of heterozygosity of EPHB2 in colorectal cancer.
Cancer letters 2001;164(1):97-104.
2001: You-Jie Wang; S M Oba; Shigeto Yoshii; Jian-Ping Song; Y Wang; Masao Kanamori; Satoshi Ota; Masamitsu Tanaka; Haruhiko Sugimura
Genomic structure of human alpha-pix, and variable deletions in a poly (T) tract in gastric cancer tissue.
Cancer letters 2001;164(1):69-75.
2001: Takahisa Furuta; Naohito Shirai; Misako Takashima; Fang Xiao; Hiroyuki Hanai; Haruhiko Sugimura; Kyoichi Ohashi; Takashi Ishizaki; Eizo Kaneko
Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin.
Clinical pharmacology and therapeutics 2001;69(3):158-68.
2000: K Kobayashi; Yasuhiko Kitayama; Hisaki Igarashi; G Yoshino; Toshihiko Kobayashi; T Kazui; Haruhiko Sugimura
Intratumor heterogeneity of centromere numerical abnormality in multiple primary gastric cancers: application of fluorescence in situ hybridization with intermittent microwave irradiation on paraffin-embedded tissue.
Japanese journal of cancer research : Gann 2000;91(11):1134-41.
2000: Hisaki Igarashi; Kiyoko Nagura; Haruhiko Sugimura
Trypan blue as a slow migrating dye for SSCP detection in polyacrylamide gel electrophoresis.
BioTechniques 2000;29(1):42-4.
2000: Tetsuo Nishimura; M Nozue; Kazuo Suzuki; M Imai; Shohachi Suzuki; Harumi Sakahara; T Nakamura; Haruhiko Sugimura
Perianal mucinous carcinoma successfully treated with a combination of external beam radiotherapy and high dose rate interstitial brachytherapy.
The British journal of radiology 2000;73(870):661-4.
2000: H Ando; T Nishimura; T Nakamura; Haruhiko Sugimura; Satoshi Nakamura
Chemoradiation therapy for squamous cell carcinoma of anal canal cancer: report of a case.
Radiation medicine 2000;18(3):199-203.
2000: DY Wang; YY Xiang; X J Li; M Hashimoto; Masamitsu Tanaka; Haruhiko Sugimura
Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.
Pathology international 2000;50(5):373-83.
2000: Yasuhiko Kitayama; Hisaki Igarashi; Haruhiko Sugimura
Initial intermittent microwave irradiation for fluorescence in situ hybridization analysis in paraffin-embedded tissue sections of gastrointestinal neoplasia.
Laboratory investigation; a journal of technical methods and pathology 2000;80(5):779-81.
2000: Kazuya Shinmura; Takashi Kohno; M Takeuchi-Sasaki; M Maeda; T Segawa; T Kamo; Haruhiko Sugimura; Jun Yokota
Expression of the OGG1-type 1a (nuclear form) protein in cancerous and non-cancerous human cells.
International journal of oncology 2000;16(4):701-7.
2000: N Saigusa; T Kurahashi; Toshio Nakamura; Haruhiko Sugimura; Shozo Baba; Hiroyuki Konno; Satoshi Nakamura
Functional outcome of stapled ileal pouch-anal canal anastomosis versus handsewn pouch-anal anastomosis.
Surgery today 2000;30(7):575-81.
2000: Manabu Ohta; Hiroyuki Konno; Kinji Kamiya; D Suwa; Megumi Baba; Tatsuo Tanaka; Toshio Nakamura; N Nishino; Haruhiko Sugimura; Satoshi Nakamura
Crohn's disease of the esophagus: report of a case.
Surgery today 2000;30(3):262-7.
2000: Isao Matsushita; Hiroyuki Hanai; Yoshihiko Sato; Hajime Arai; Takayuki Iida; Y Hosoda; E Kaneko; Kazuhiko Yasumi; Haruhiko Sugimura
Protein-losing enteropathy caused by mesenteric venous thrombosis with protein C deficiency.
Journal of clinical gastroenterology 2000;30(1):94-7.
1999: Yasuhiko Kitayama; Hisaki Igarashi; Haruhiko Sugimura
Amplification of FISH signals using intermittent microwave irradiation for analysis of chromosomal instability in gastric cancer.
Molecular pathology : MP 1999;52(6):357-9.
1999: Shigeto Yoshii; Masamitsu Tanaka; Yoshiro Otsuki; DY Wang; Rong-Jun Guo; Y Zhu; R Takeda; Hiroyuki Hanai; E Kaneko; Haruhiko Sugimura
alphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase.
Oncogene 1999;18(41):5680-90.
1999: Haruhiko Sugimura; T Kohno; K Wakai; Kiyoko Nagura; K Genka; Hisaki Igarashi; B J Morris; S Baba; Y Ohno; C Gao; Zhongyou Li; J Wang; T Takezaki; K Tajima; T Varga; T Sawaguchi; J K Lum; J J Martinson; Shoichiro Tsugane; Teruo Iwamasa; Kazuya Shinmura; Jun Yokota
hOGG1 Ser326Cys polymorphism and lung cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(8):669-74.
1999: Kazuo Suzuki; Teruhisa Kazui; M Yoshida; T Uno; T Kobayashi; T Kimura; T Yoshida; Haruhiko Sugimura
Drug-induced apoptosis and p53, BCL-2 and BAX expression in breast cancer tissues in vivo and in fibroblast cells in vitro.
Japanese journal of clinical oncology 1999;29(7):323-31.
1999: X J Li; DY Wang; Y Zhu; Rong-Jun Guo; X D Wang; K Lubomir; K Mukai; H Sasaki; H Yoshida; T Oka; R Machinami; Kazuya Shinmura; Masamitsu Tanaka; Haruhiko Sugimura
Mxi1 mutations in human neurofibrosarcomas.
Japanese journal of cancer research : Gann 1999;90(7):740-6.
1999: Jun Isogaki; Kazuya Shinmura; W Yin; T Arai; K Koda; T Kimura; I Kino; Haruhiko Sugimura
Microsatellite instability and K-ras mutations in gastric adenomas, with reference to associated gastric cancers.
Cancer detection and prevention 1999;23(3):204-14.
1998: Y Wang; Kazuya Shinmura; Rong-Jun Guo; Jun Isogaki; DY Wang; I Kino; Haruhiko Sugimura
Mutational analyses of multiple target genes in histologically heterogeneous gastric cancer with microsatellite instability.
Japanese journal of cancer research : Gann 1998;89(12):1284-91.
1998: Masamitsu Tanaka; DY Wang; Takaharu Kamo; Hisaki Igarashi; Y Wang; YY Xiang; Fumihiko Tanioka; Y Naito; Haruhiko Sugimura
Interaction of EphB2-tyrosine kinase receptor and its ligand conveys dorsalization signal in Xenopus laevis development.
Oncogene 1998;17(12):1509-16.
1998: Hiroyuki Konno; T Arai; Tatsuo Tanaka; Megumi Baba; K Matsumoto; T Kanai; Satoshi Nakamura; Shozo Baba; Y Naito; Haruhiko Sugimura; A Yukita; M Asano; H Suzuki
Antitumor effect of a neutralizing antibody to vascular endothelial growth factor on liver metastasis of endocrine neoplasm.
Japanese journal of cancer research : Gann 1998;89(9):933-9.
1998: Rong-Jun Guo; Y Wang; E Kaneko; DY Wang; Hajime Arai; Hiroyuki Hanai; S Takenoshita; K Hagiwara; C C Harris; Haruhiko Sugimura
Analyses of mutation and loss of heterozygosity of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human gastric cancer.
Carcinogenesis 1998;19(9):1539-44.
1998: Kazuya Shinmura; Takashi Kohno; H Kasai; K Koda; Haruhiko Sugimura; Jun Yokota
Infrequent mutations of the hOGG1 gene, that is involved in the excision of 8-hydroxyguanine in damaged DNA, in human gastric cancer.
Japanese journal of cancer research : Gann 1998;89(8):825-8.
1998: Y Naito; K Ohori; Masamitsu Tanaka; T Kamo; S Baba; T Hori; K Hashizume; Haruhiko Sugimura
Collagen and elastin synthesis by desmoid tumor in vitro.
Pathology international 1998;48(8):603-10.
1998: Takashi Kohno; Kazuya Shinmura; M Tosaka; M Tani; SR Kim; Haruhiko Sugimura; T Nohmi; H Kasai; Jun Yokota
Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA.
Oncogene 1998;16(25):3219-25.
1998: Haruhiko Sugimura; K Wakai; K Genka; Kiyoko Nagura; Hisaki Igarashi; K Nagayama; A Ohkawa; S Baba; B J Morris; Shoichiro Tsugane; Y Ohno; C Gao; Zhongyou Li; T Takezaki; K Tajima; Teruo Iwamasa
Association of Ile462Val (Exon 7) polymorphism of cytochrome P450 IA1 with lung cancer in the Asian population: further evidence from a case-control study in Okinawa.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(5):413-7.
1998: H Uchida; H Ando; Keiji Maruyama; H Kobayashi; H Toda; H Ogawa; T Ozawa; Y Matsuda; Haruhiko Sugimura; T Kanno; Shozo Baba
Genetic alterations of mixed hyperplastic adenomatous polyps in the colon and rectum.
Japanese journal of cancer research : Gann 1998;89(3):299-306.
1998: Kazuhiko Yasumi; Rong-Jun Guo; Hiroyuki Hanai; Hajime Arai; E Kaneko; Hiroyuki Konno; S Takenoshita; K Hagiwara; Haruhiko Sugimura
Transforming growth factor beta type II receptor (TGF beta RII) mutation in gastric lymphoma without mutator phenotype.
Pathology international 1998;48(2):134-7.
1998: Kazuya Shinmura; M Tani; Jun Isogaki; Y Wang; Haruhiko Sugimura; Jun Yokota
RER phenotype and its associated mutations in familial gastric cancer.
Carcinogenesis 1998;19(2):247-51.
1997: Kazuya Shinmura; H Kasai; A Sasaki; Haruhiko Sugimura; Jun Yokota
8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity.
Mutation research 1997;385(1):75-82.
1997: Kazuya Shinmura; W Yin; Jun Isogaki; K Saitoh; K Kanazawa; K Koda; Jun Yokota; I Kino; T Arai; Haruhiko Sugimura
Stage-dependent evaluation of microsatellite instability in gastric carcinoma with familial clustering.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1997;6(9):693-7.
1997: Y Wang; K Shinmura; Haruhiko Sugimura
[Microsatellite instability in gastric cancer with varied structure].
Rinsho byori. The Japanese journal of clinical pathology 1997;45(7):651-5.
1997: YY Xiang; DY Wang; Masamitsu Tanaka; Mika Suzuki; E Kiyokawa; Hisaki Igarashi; Y Naito; Q Shen; Haruhiko Sugimura
Expression of high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa.
International journal of cancer. Journal international du cancer 1997;74(1):1-6.
1997: M Kasami; M Yoshida; Jun Isogaki; H Ogawa; Kazuya Shinmura; Y Endo; E Kiyokawa; Y Naito; T Arai; T Kimura; R Inoue; Haruhiko Sugimura
Bilateral breast tumors, malignant phyllodes tumor and invasive lobular carcinoma in a 46,XX/46,XY mosaic female with family history of breast cancer.
Pathology international 1997;47(2-3):147-54.
1997: T Kanai; Hiroyuki Konno; K Maruyama; Megumi Baba; Tatsuo Tanaka; Y Maruo; N Nishino; Satoshi Nakamura; Satoshi Baba; Haruhiko Sugimura
p53 overexpression and proliferative activity do not correlate with lymph node metastasis in early gastric cancer.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1997;29(1):35-41.
1996: D Y Wang; Y Y Xiang; M Tanaka; Q Shen; Haruhiko Sugimura
Identification of cytokeratin subspecies altered in rat experimental esophageal tumors by subtractive cloning.
Cancer letters 1996;108(1):119-27.
1996: Y Y Xiang; D Y Wang; M Tanaka; H Igarashi; Y Naito; Yoshihisa Ohtawara; Q Shen; Haruhiko Sugimura
Expression of structure-specific recognition protein mRNA in fetal kidney and Fe-nitrilotriacetate-induced renal carcinoma in the rat.
Cancer letters 1996;106(2):271-8.
1996: K Maruyama; Tatsuo Tanaka; S Baba; Satoshi Nakamura; Y Endo; Haruhiko Sugimura
p53 accumulation in colorectal cancer with hepatic metastasis.
Japanese journal of cancer research : Gann 1996;87(4):368-76.
1996: T Iwase; M Nishimura; Haruhiko Sugimura; Hisaki Igarashi; Fukujirou Ozawa; Kazuya Shinmura; M Suzuki; Masamitsu Tanaka; I Kino
Localization of Menkes gene expression in the mouse brain; its association with neurological manifestations in Menkes model mice.
Acta neuropathologica 1996;91(5):482-8.
1995: Kazuya Shinmura; Haruhiko Sugimura; Y Naito; P G Shields; I Kino
Frequent co-occurrence of mutator phenotype in synchronous, independent multiple cancers of the stomach.
Carcinogenesis 1995;16(12):2989-93.
1995: Y Endo; Haruhiko Sugimura; I Kino
Monoclonality of normal human colonic crypts.
Pathology international 1995;45(8):602-4.
1995: Y Y Xiang; D Y Wang; M Tanaka; H Igarashi; T Kamo; Q Shen; Haruhiko Sugimura; I Kino
Efficient and specific induction of esophageal tumors in rats by precursors of N-nitrososarcosine ethyl ester.
Pathology international 1995;45(6):415-21.
1995: Y Kitayama; Satoshi Nakamura; Haruhiko Sugimura; I Kino
Cytophotometric and flow cytometric DNA content of isolated glands in gastric neoplasia.
Gut 1995;36(4):516-21.
1995: Y Kitayama; Haruhiko Sugimura; T Arai; K Nagamatsu; I Kino
Primary osteosarcoma arising from cirrhotic liver.
Pathology international 1995;45(4):320-5.
1995: Y Kitayama; Haruhiko Sugimura; M Tanaka; Satoshi Nakamura; I Kino
Expression of p53 and flow cytometric DNA analysis of isolated neoplastic glands of the stomach: an application of the gland isolation method.
Virchows Archiv : an international journal of pathology 1995;426(6):557-62.
1995: Haruhiko Sugimura; G S Hamada; I Suzuki; T Iwase; E Kiyokawa; I Kino; Shoichiro Tsugane
CYP1A1 and CYP2E1 polymorphism and lung cancer, case-control study in Rio de Janeiro, Brazil.
Pharmacogenetics 1995;5 Spec No():S145-8.
1995: G S Hamada; Haruhiko Sugimura; I Suzuki; Kiyoko Nagura; E Kiyokawa; T Iwase; M Tanaka; T Takahashi; S Watanabe; I Kino
The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the RsaI polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1995;4(1):63-7.
1994: E Kiyokawa; S Takai; M Tanaka; T Iwase; M Suzuki; Y Y Xiang; Y Naito; K Yamada; Haruhiko Sugimura; I Kino
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors.
Cancer research 1994;54(14):3645-50.
1994: Y Y Xiang; M Tanaka; M Suzuki; H Igarashi; E Kiyokawa; Y Naito; Yoshihisa Ohtawara; Q Shen; Haruhiko Sugimura; I Kino
Isolation of complementary DNA encoding K-cadherin, a novel rat cadherin preferentially expressed in fetal kidney and kidney carcinoma.
Cancer research 1994;54(11):3034-41.
1994: T Arai; Haruhiko Sugimura; M Suzuki; T Iwase; S Sakuramachi; T Kimura; Y Harada; I Kino
Benign schwannoma of the esophagus: report of two cases with immunohistochemical and ultrastructural studies.
Pathology international 1994;44(6):460-5.
1994: H Igarashi; Haruhiko Sugimura; K Maruyama; Y Kitayama; I Ohta; M Suzuki; M Tanaka; Y Dobashi; I Kino
Alteration of immunoreactivity by hydrated autoclaving, microwave treatment, and simple heating of paraffin-embedded tissue sections.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1994;102(4):295-307.
1994: Haruhiko Sugimura; I Suzuki; G S Hamada; T Iwase; T Takahashi; Kiyoko Nagura; H Iwata; S Watanabe; I Kino; Shoichiro Tsugane
Cytochrome P-450 lA1 genotype in lung cancer patients and controls in Rio de Janeiro, Brazil.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(2):145-8.
1993: M Shiseki; R Nishikawa; H Yamamoto; A Ochiai; Haruhiko Sugimura; N Shitara; Y Sameshima; H Mizoguchi; T Sugimura; Jun Yokota
Germ-line p53 mutation is uncommon in patients with triple primary cancers.
Cancer letters 1993;73(1):51-7.