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Kaza Suguna

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Anita Rachel Chacko; Eleanor J Dodson; C Durga Rao; Randy J Read; Peter H Zwart; Kaza Suguna
Severe diffraction anisotropy, rotational pseudosymmetry and twinning complicate the refinement of a pentameric coiled-coil structure of NSP4 of rotavirus.
Koustav Maity; Avadhesha Surolia; Namita Surolia; Preeti Bajaj; Kaza Suguna
Insights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studies.
Kartika Shetty; Ganapati G Bhat; Shashikala R Inamdar; Bale M Swamy; Kaza Suguna
Crystal structure of a β-prism II lectin from Remusatia vivipara.

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2012: Anita Rachel Chacko; Eleanor J Dodson; C Durga Rao; Randy J Read; Peter H Zwart; Kaza Suguna
Severe diffraction anisotropy, rotational pseudosymmetry and twinning complicate the refinement of a pentameric coiled-coil structure of NSP4 of rotavirus.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 11):1541-8.
2012: Koustav Maity; Avadhesha Surolia; Namita Surolia; Preeti Bajaj; Kaza Suguna
Insights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studies.
Journal of biomolecular structure & dynamics 2012;29(5):973-83.
2012: Kartika Shetty; Ganapati G Bhat; Shashikala R Inamdar; Bale M Swamy; Kaza Suguna
Crystal structure of a β-prism II lectin from Remusatia vivipara.
Glycobiology 2012;22(1):56-69.
2011: Anita Rachel Chacko; Eleanor J Dodson; Jeyaraman Jeyakanthan; Durga C Rao; Randy J Read; Narayan P Sastri; Kanagaraj Sekar; Mohammed Arifullah; Go Ueno; Kaza Suguna
Novel pentameric structure of the diarrhea-inducing region of the rotavirus enterotoxigenic protein NSP4.
Journal of virology 2011;85(23):12721-32.
2011: Koustav Maity; Avadhesha Surolia; Namita Surolia; Bharat Somireddy Venkata; Neha Kapoor; Kaza Suguna
Structural basis for the functional and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum.
Journal of structural biology 2011;176(2):238-49.
2011: Ashish Arora; Nagasuma R Chandra; Amit Das; Balasubramanian Gopal; Shekhar C Mande; Balaji Prakash; Ravishankar Ramachandran; Rajan Sankaranarayanan; K Sekar; Kaza Suguna; Anil K Tyagi; Mamannamana Vijayan
Structural biology of Mycobacterium tuberculosis proteins: the Indian efforts.
Tuberculosis (Edinburgh, Scotland) 2011;91(5):456-68.
2011: Subbiah Thamotharan; Tangavelou Karthikeyan; Kiran A Kulkarni; Kartika N Shetty; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Modification of the sugar specificity of a plant lectin: structural studies on a point mutant of Erythrina corallodendron lectin.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 3):218-27.
2011: Koustav Maity; Tanushree Banerjee; Narayanappa Prabakaran; Namita Surolia; Avadhesha Surolia; Kaza Suguna
Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparum.
IUBMB life 2011;63(1):30-41.
2010: Koustav Maity; Saligram Prabhakar Bhargav; Banumathi Sankaran; Namita Surolia; Avadhesha Surolia; Kaza Suguna
X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition.
IUBMB life 2010;62(6):467-76.
2009: Lakshmi S Pidugu; Koustav Maity; Karthikeyan Ramaswamy; Namita Surolia; Kaza Suguna
Analysis of proteins with the 'hot dog' fold: prediction of function and identification of catalytic residues of hypothetical proteins.
BMC structural biology 2009;9():37.
2008: Ritwick Sawarkar; Nainita Roy; Sanjana Rao; Swetha Raman; S Venketesh; Kaza Suguna; Utpal Tatu
Heat shock protein 90 regulates development in Dictyostelium discoideum.
Journal of molecular biology 2008;383(1):24-35.
2008: Kiran A Kulkarni; Samiksha Katiyar; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Structure and sugar-specificity of basic winged-bean lectin: structures of new disaccharide complexes and a comparative study with other known disaccharide complexes of the lectin.
Acta crystallographica. Section D, Biological crystallography 2008;D64(Pt 7):730-7.
2008: Deepa Rajasekaran; Narayan P Sastri; Jagannath R Marathahalli; Shanthinath S Indi; Kiranmayee Pamidimukkala; Kaza Suguna; C Durga Rao
The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties.
The Journal of general virology 2008;89(Pt 6):1485-96.
2007: Kiran A Kulkarni; Samiksha Katiyar; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Generation of blood group specificity: new insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin.
Proteins 2007;68(3):762-9.
2007: Krishanpal Karmodiya; Sajad Hussain Syed; Sharmistha Sinha; Koustav Maity; Kaza Suguna; Namita Surolia
Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum beta-ketoacyl-ACP reductase.
IUBMB life 2007;59(7):441-9.
2007: Pidugu Lakshmi Swarnamukhi; Shailendra Kumar Sharma; Prasanth Padala; Namita Surolia; Avadhesha Surolia; Kaza Suguna
Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 4):458-64.
2007: R Deepa; C Durga Rao; Kaza Suguna
Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4.
Archives of virology 2007;152(5):847-59.
2006: Kiran A Kulkarni; Samiksha Katiyar; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 11):1319-24.
2006: P Lakshmi Swarnamukhi; Shailendra Kumar Sharma; Preeti Bajaj; Namita Surolia; Avadhesha Surolia; Kaza Suguna
Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips.
FEBS letters 2006;580(11):2653-60.
2006: Amit D Ketkar; Avinash R Shenoy; Udupi A Ramagopal; Sandhya S Visweswariah; Kaza Suguna
A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis.
Journal of molecular biology 2006;356(4):904-16.
2006: V Lavanya Latha; Kiran A Kulkarni; Rameshwaram Nagender Rao; neeraj kumar; Kaza Suguna
Crystallization and preliminary X-ray crystallographic analysis of a galactose-specific lectin from Dolichos lablab.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):163-5.
2006: MR Jagannath; muppuru kesavulu; R Deepa; P Narayan Sastri; S Senthil Kumar; Kaza Suguna; C Durga Rao
N- and C-terminal cooperation in rotavirus enterotoxin: novel mechanism of modulation of the properties of a multifunctional protein by a structurally and functionally overlapping conformational domain.
Journal of virology 2006;80(1):412-25.
2005: Kiran A Kulkarni; Sharmistha Sinha; Samiksha Katiyar; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Structural basis for the specificity of basic winged bean lectin for the Tn-antigen: a crystallographic, thermodynamic and modelling study.
FEBS letters 2005;579(30):6775-80.
2005: muppuru kesavulu; A S Prakasha Gowda; T N C Ramya; Namita Surolia; Kaza Suguna
Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis.
The journal of peptide research : official journal of the American Peptide Society 2005;66(4):211-9.
2005: muppuru kesavulu; Sundaramoorthy Ramasubramanian; Kaza Suguna
Effect of dimethyl sulphoxide on the crystal structure of porcine pepsin.
Biochemical and biophysical research communications 2005;331(4):1510-4.
2004: Lakshmi Swarnamukhi Pidugu; Mili Kapoor; Namita Surolia; Avadhesha Surolia; Kaza Suguna
Structural basis for the variation in triclosan affinity to enoyl reductases.
Journal of molecular biology 2004;343(1):147-55.
2004: Kiran A Kulkarni; A Srivastava; Nivedita Mitra; N Sharon; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Effect of glycosylation on the structure of Erythrina corallodendron lectin.
Proteins 2004;56(4):821-7.
2004: Mili Kapoor; P L Swarna Mukhi; Namita Surolia; Kaza Suguna; Avadhesha Surolia
Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD+.
The Biochemical journal 2004;381(Pt 3):725-33.
2004: Amit D Ketkar; Avinash R Shenoy; muppuru kesavulu; Sandhya S Visweswariah; Kaza Suguna
Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):371-3.
2004: S Kundhavai Natchiar; A Arockia Jeyaprakash; T N C Ramya; Celestine J Thomas; Kaza Suguna; Avadhesha Surolia; Mamannamana Vijayan
Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 2):211-9.
2004: R Deepa; MR Jagannath; muppuru kesavulu; C Durga Rao; Kaza Suguna
Expression, purification, crystallization and preliminary crystallographic analysis of the diarrhoea-causing and virulence-determining region of rotaviral nonstructural protein NSP4.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 1):135-6.
2004: Pidugu Lakshmi Swarna Mukhi; Shailendra Kumar Sharma; Mili Kapoor; Namita Surolia; Avadhesha Surolia; Kaza Suguna
Crystallization and preliminary crystallographic analysis of beta-hydroxyacyl ACP dehydratase (FabZ) from Plasmodium falciparum.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 1):120-1.
2003: B V L S Prasad; Kaza Suguna
Effect of pH on the structure of rhizopuspepsin.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 10):1755-61.
2003: Muralidharan Jayaraman; Kaza Suguna; Avadhesha Surolia; Namita Surolia
Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases.
Journal of biomolecular structure & dynamics 2003;20(4):589-94.
2002: B V L S Prasad; Kaza Suguna
Role of water molecules in the structure and function of aspartic proteinases.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):250-9.
2001: Nagasuma R Chandra; MM Prabu; Kaza Suguna; Mamannamana Vijayan
Structural similarity and functional diversity in proteins containing the legume lectin fold.
Protein engineering 2001;14(11):857-66.
2001: N Manoj; Kaza Suguna
Signature of quaternary structure in the sequences of legume lectins.
Protein engineering 2001;14(10):735-45.
2001: R Bhandari; Narayanaswamy Srinivasan; M Mahaboobi; Yashoda Ghanekar; Kaza Suguna; Sandhya S Visweswariah
Functional inactivation of the human guanylyl cyclase C receptor: modeling and mutation of the protein kinase-like domain.
Biochemistry 2001;40(31):9196-206.
2001: R Ravishankar; Celestine J Thomas; Kaza Suguna; Avadhesha Surolia; Mamannamana Vijayan
Crystal structures of the peanut lectin-lactose complex at acidic pH: retention of unusual quaternary structure, empty and carbohydrate bound combining sites, molecular mimicry and crystal packing directed by interactions at the combining site.
Proteins 2001;43(3):260-70.
2001: Kaza Suguna; Avadhesha Surolia; Namita Surolia
Structural basis for triclosan and NAD binding to enoyl-ACP reductase of Plasmodium falciparum.
Biochemical and biophysical research communications 2001;283(1):224-8.
2000: K Vijayachandra; MR Guruprasad; R Bhandari; U H Manjunath; B P Somesh; Narayanaswamy Srinivasan; Kaza Suguna; Sandhya S Visweswariah
Biochemical characterization of the intracellular domain of the human guanylyl cyclase C receptor provides evidence for a catalytically active homotrimer.
Biochemistry 2000;39(51):16075-83.
2000: N Manoj; VR Srinivas; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Carbohydrate specificity and salt-bridge mediated conformational change in acidic winged bean agglutinin.
Journal of molecular biology 2000;302(5):1129-37.
1999: R Ravishankar; Kaza Suguna; Avadhesha Surolia; Mamannamana Vijayan
Structures of the complexes of peanut lectin with methyl-beta-galactose and N-acetyllactosamine and a comparative study of carbohydrate binding in Gal/GalNAc-specific legume lectins.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 8):1375-82.
1999: R Bhandari; Kaza Suguna; Sandhya S Visweswariah
Guanylyl cyclase C receptor: regulation of catalytic activity by ATP.
Bioscience reports 1999;19(3):179-88.
1999: MM Prabu; Kaza Suguna; Mamannamana Vijayan
Variability in quaternary association of proteins with the same tertiary fold: a case study and rationalization involving legume lectins.
Proteins 1999;35(1):58-69.
1999: N Manoj; VR Srinivas; Kaza Suguna
Structure of basic winged-bean lectin and a comparison with its saccharide-bound form.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 4):794-800.
1999: N Manoj; VR Srinivas; Satish Bharadwaj; N C Singha; Kaza Suguna
Crystallization and preliminary crystallographic analysis of winged bean acidic lectin.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 2):564-5.
1998: A Nandi; Kaza Suguna; Avadhesha Surolia; Sandhya S Visweswariah
Topological mimicry and epitope duplication in the guanylyl cyclase C receptor.
Protein science : a publication of the Protein Society 1998;7(10):2175-83.
1998: MM Prabu; R Sankaranarayanan; K D Puri; Vivek Sharma; Avadhesha Surolia; Mamannamana Vijayan; Kaza Suguna
Carbohydrate specificity and quaternary association in basic winged bean lectin: X-ray analysis of the lectin at 2.5 A resolution.
Journal of molecular biology 1998;276(4):787-96.
1996: R Banerjee; Kalyan Das; R Ravishankar; Kaza Suguna; Avadhesha Surolia; Mamannamana Vijayan
Conformation, protein-carbohydrate interactions and a novel subunit association in the refined structure of peanut lectin-lactose complex.
Journal of molecular biology 1996;259(2):281-96.
1995: R V Kishan; Nagasuma R Chandra; C Sudarsanakumar; Kaza Suguna; Mamannamana Vijayan
Water-dependent domain motion and flexibility in ribonuclease A and the invariant features in its hydration shell. An X-ray study of two low-humidity crystal forms of the enzyme.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 5):703-10.
1994: R Banerjee; S C Mande; V Ganesh; Kalyan Das; V Dhanaraj; S K Mahanta; Kaza Suguna; Avadhesha Surolia; Mamannamana Vijayan
Crystal structure of peanut lectin, a protein with an unusual quaternary structure.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):227-31.