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M-Saadeh Suleiman

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Shang-Jin Kim; Hua Lin; James T Milnes; M-Saadeh Suleiman; Haifei Zhang; Richard Bond; Stéphanie C M Choisy; Said El Haou; Jules C Hancox; Igor Khaliulin; Andrew F James
Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia.
Nicola King; Madj Al Shaama; M-Saadeh Suleiman
Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion.
Xun Liu; Else M Løberg; M-Saadeh Suleiman; James Tooley; Marianne Thoresen
Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs.

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2012: Shang-Jin Kim; Hua Lin; James T Milnes; M-Saadeh Suleiman; Haifei Zhang; Richard Bond; Stéphanie C M Choisy; Said El Haou; Jules C Hancox; Igor Khaliulin; Andrew F James
Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia.
Circulation. Arrhythmia and electrophysiology 2012;5(6):1184-92.
2012: Nicola King; Madj Al Shaama; M-Saadeh Suleiman
Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion.
Pflügers Archiv : European journal of physiology 2012;464(5):513-22.
2011: Xun Liu; Else M Løberg; M-Saadeh Suleiman; James Tooley; Marianne Thoresen
Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs.
Pediatric research 2011;70(4):352-6.
2011: Massimo Caputo; Carlo Fino; Claudio Grossi; Marco Agostini; Gianni D Angelini; Kirkpatrick C Santo; M-Saadeh Suleiman; Barnaby C Reeves
Warm-blood cardioplegia with low or high magnesium for coronary bypass surgery: a randomised controlled trial.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2011;40(3):722-9.
2011: Igor Khaliulin; Andrew P Halestrap; M-Saadeh Suleiman
Temperature preconditioning is optimal at 26° C and confers additional protection to hypothermic cardioplegic ischemic arrest.
Experimental biology and medicine (Maywood, N.J.) 2011;236(6):736-45.
2011: Hajime Imura; Hua Lin; Elinor J Griffiths; M-Saadeh Suleiman
Controlled hyperkalemic reperfusion with magnesium rescues ischemic juvenile hearts by reducing calcium loading.
The Journal of thoracic and cardiovascular surgery 2011;141(6):1529-37.
2011: Nicola King; Hua Lin; M-Saadeh Suleiman
Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in freshly isolated rat cardiomyocytes.
Amino acids 2011;40(2):517-26.
2010: Nicola King; Hua Lin; M-Saadeh Suleiman
Cysteine protects freshly isolated cardiomyocytes against oxidative stress by stimulating glutathione peroxidase.
Molecular and cellular biochemistry 2010;343(1-2):125-32.
2009: Hajime Imura; Massimo Caputo; Kelvin Lim; Masami Ochi; M-Saadeh Suleiman; Kazuo Shimizu; Gianni Angelini
Pulmonary injury after cardiopulmonary bypass: beneficial effects of low-frequency mechanical ventilation.
The Journal of thoracic and cardiovascular surgery 2009;137(6):1530-7.
2009: Paul Modi; M-Saadeh Suleiman
Invited commentary.
The Annals of thoracic surgery 2009;87(5):1523-4.
2007: Anabelle Chase; Christopher L Jackson; Gianni Angelini; M-Saadeh Suleiman
Coronary artery disease progression is associated with increased resistance of hearts and myocytes to cardiac insults.
Critical care medicine 2007;35(10):2344-51.
2007: Igor Khaliulin; Samantha J Clarke; Hua Lin; Joanna Parker; M-Saadeh Suleiman; Andrew P Halestrap
Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore.
The Journal of physiology 2007;581(Pt 3):1147-61.
2007: M-Saadeh Suleiman; R J R Singh; Claire E H Stewart
Apoptosis and the cardiac action of insulin-like growth factor I.
Pharmacology & therapeutics 2007;114(3):278-94.
2006: Nicola King; Hua Lin; John D McGivan; M-Saadeh Suleiman
Expression and activity of the glutamate transporter EAAT2 in cardiac hypertrophy: implications for ischaemia reperfusion injury.
Pflügers Archiv : European journal of physiology 2006;452(6):674-82.
2006: Rahat S Warraich; Elinor Griffiths; Andrew Falconar; Vijay Pabbathi; Chris Bell; Gianni Angelini; M-Saadeh Suleiman; Magdi H Yacoub
Human cardiac myosin autoantibodies impair myocyte contractility: a cause-and-effect relationship.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):651-60.
2006: Paul Modi; M-Saadeh Suleiman; Barney Reeves; Ash Pawade; Andrew J Parry; Gianni Angelini; Massimo Caputo
Free amino acids in hearts of pediatric patients with congenital heart disease: the effects of cyanosis, age, and pathology.
The Annals of thoracic surgery 2006;81(3):943-9.
2005: Kelvin H H Lim; Andrew P Halestrap; Gianni Angelini; M-Saadeh Suleiman
Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass.
Experimental biology and medicine (Maywood, N.J.) 2005;230(6):413-20.
2004: Nicola King; S Korolchuk; John D McGivan; M-Saadeh Suleiman
A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes.
Journal of pharmacological and toxicological methods 2004;50(3):215-22.
2004: Paul Modi; M-Saadeh Suleiman; Barney Reeves; Ash Pawade; Andrew J Parry; Gianni Angelini; Massimo Caputo
Basal metabolic state of hearts of patients with congenital heart disease: the effects of cyanosis, age, and pathology.
The Annals of thoracic surgery 2004;78(5):1710-6.
2004: Paul Modi; M-Saadeh Suleiman; Barney Reeves; Ash Pawade; Andrew J Parry; Gianni Angelini; Massimo Caputo
Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques.
The Journal of thoracic and cardiovascular surgery 2004;128(1):67-75.
2004: Nicola King; Hua Lin; John D McGivan; M-Saadeh Suleiman
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
The Journal of physiology 2004;556(Pt 3):849-58.
2004: Paul Modi; M-Saadeh Suleiman
Myocardial taurine, development and vulnerability to ischemia.
Amino acids 2004;26(1):65-70.
2003: Attilio Lotto; Raimondo Ascione; Massimo Caputo; Alan J Bryan; Gianni Angelini; M-Saadeh Suleiman
Myocardial protection with intermittent cold blood during aortic valve operation: antegrade versus retrograde delivery.
The Annals of thoracic surgery 2003;76(4):1227-33; discussion 1233.
2003: Hua Lin; M-Saadeh Suleiman
Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia.
Pflügers Archiv : European journal of physiology 2003;447(1):8-13.
2003: Nicola King; John D McGivan; Elinor J Griffiths; Andrew P Halestrap; M-Saadeh Suleiman
Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation.
Journal of molecular and cellular cardiology 2003;35(8):975-84.
2003: Paul Modi; Hajime Imura; Gianni Angelini; Ash Pawade; Andrew J Parry; M-Saadeh Suleiman; Massimo Caputo
Pathology-related troponin I release and clinical outcome after pediatric open heart surgery.
Journal of cardiac surgery 2003;18(4):295-300.
2002: Kelvin H H Lim; Sabzali Javadov; Manika Das; Samantha J Clarke; M-Saadeh Suleiman; Andrew P Halestrap
The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration.
The Journal of physiology 2002;545(Pt 3):961-74.
2002: Hajime Imura; Paul Modi; Ash Pawade; Andrew J Parry; M-Saadeh Suleiman; Gianni Angelini; Massimo Caputo
Cardiac troponin I in neonates undergoing the arterial switch operation.
The Annals of thoracic surgery 2002;74(6):1998-2002.
2002: Paul Modi; Hajime Imura; Massimo Caputo; Ash Pawade; Andrew J Parry; Gianni Angelini; M-Saadeh Suleiman
Cardiopulmonary bypass-induced myocardial reoxygenation injury in pediatric patients with cyanosis.
The Journal of thoracic and cardiovascular surgery 2002;124(5):1035-6.
2002: Hajime Imura; Ben E Ayres; M-Saadeh Suleiman
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Molecular and cellular biochemistry 2002;237(1-2):119-27.
2002: Massimo Caputo; Paul Modi; Hajime Imura; Ash Pawade; Andrew J Parry; M-Saadeh Suleiman; Gianni Angelini
Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial.
The Annals of thoracic surgery 2002;74(2):530-4; discussion 535.
2002: Raimondo Ascione; Massimo Caputo; Walter J Gomes; Attilio Lotto; Alan J Bryan; Gianni Angelini; M-Saadeh Suleiman
Myocardial injury in hypertrophic hearts of patients undergoing aortic valve surgery using cold or warm blood cardioplegia.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2002;21(3):440-6.
2001: H Williams; Nicola King; Elinor J Griffiths; M-Saadeh Suleiman
Glutamate-loading stimulates metabolic flux and improves cell recovery following chemical hypoxia in isolated cardiomyocytes.
Journal of molecular and cellular cardiology 2001;33(12):2109-19.
2001: Nicola King; H Williams; John D McGivan; M-Saadeh Suleiman
Characteristics of L-aspartate transport and expression of EAAC-1 in sarcolemmal vesicles and isolated cells from rat heart.
Cardiovascular research 2001;52(1):84-94.
2001: Nicola King; M-Saadeh Suleiman
L-leucine transport in rat heart under normal conditions and effects of a simulated hypoxia.
Molecular and cellular biochemistry 2001;221(1-2):99-108.
2001: Hajime Imura; Massimo Caputo; Andrew J Parry; Ash Pawade; Gianni Angelini; M-Saadeh Suleiman
Age-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery.
Circulation 2001;103(11):1551-6.
2001: M-Saadeh Suleiman; Andrew P Halestrap; Elinor J Griffiths
Mitochondria: a target for myocardial protection.
Pharmacology & therapeutics 2001;89(1):29-46.
2000: H Williams; PM Kerr; M-Saadeh Suleiman; Elinor J Griffiths
Differences in the calcium-handling response of isolated rat and guinea-pig cardiomyocytes to metabolic inhibition: implications for cell damage.
Experimental physiology 2000;85(5):505-10.
2000: Sabzali Javadov; Kelvin H H Lim; PM Kerr; M-Saadeh Suleiman; Gianni Angelini; Andrew P Halestrap
Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition.
Cardiovascular research 2000;45(2):360-9.
1999: M-Saadeh Suleiman; Vincenzo Lucchetti; Massimo Caputo; Gianni Angelini
Short periods of regional ischaemia and reperfusion provoke release of troponin I from the human hearts.
Clinica chimica acta; international journal of clinical chemistry 1999;284(1):25-30.
1999: PM Kerr; M-Saadeh Suleiman; Andrew P Halestrap
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate.
The American journal of physiology 1999;276(2 Pt 2):H496-502.
1998: Massimo Caputo; Alan J Bryan; Antonio Maria Calafiore; M-Saadeh Suleiman; Gianni Angelini
Intermittent antegrade hyperkalaemic warm blood cardioplegia supplemented with magnesium prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1998;14(6):596-601.
1998: M-Saadeh Suleiman; Massimo Caputo; Raimondo Ascione; Alan J Bryan; Vincenzo Lucchetti; Walter J Gomes; Gianni Angelini
Metabolic differences between hearts of patients with aortic valve disease and hearts of patients with ischaemic disease.
Journal of molecular and cellular cardiology 1998;30(11):2519-23.
1998: Massimo Caputo; Raimondo Ascione; Gianni Angelini; M-Saadeh Suleiman; Alan J Bryan
The end of the cold era: from intermittent cold to intermittent warm blood cardioplegia.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1998;14(5):467-75.
1998: Vincenzo Lucchetti; Massimo Caputo; M-Saadeh Suleiman; M Capece; G Brando; Gianni Angelini
Beating heart coronary revascularization without metabolic myocardial damage.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1998;14(4):443-4.
1998: Nicola King; M-Saadeh Suleiman
Characteristics of L-alanine transport in cardiac sarcolemmal vesicles and into isolated cardiac myocytes.
Pflügers Archiv : European journal of physiology 1998;436(3):384-90.
1998: Elinor J Griffiths; H Lin; M-Saadeh Suleiman
NADH fluorescence in isolated guinea-pig and rat cardiomyocytes exposed to low or high stimulation rates and effect of metabolic inhibition with cyanide.
Biochemical pharmacology 1998;56(2):173-9.
1998: Massimo Caputo; Walid Dihmis; Alan J Bryan; M-Saadeh Suleiman; Gianni Angelini
Warm blood hyperkalaemic reperfusion ('hot shot') prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1998;13(5):559-64.
1998: Raimondo Ascione; Walter J Gomes; Gianni Angelini; Alan J Bryan; M-Saadeh Suleiman
Warm blood cardioplegia reduces the fall in the intracellular concentration of taurine in the ischaemic/reperfused heart of patients undergoing aortic valve surgery.
Amino acids 1998;15(4):339-50.
1997: Massimo Caputo; Walid Dihmis; I Birdi; Barney Reeves; M-Saadeh Suleiman; Gianni Angelini; Alan J Bryan
Cardiac troponin T and troponin I release during coronary artery surgery using cold crystalloid and cold blood cardioplegia.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1997;12(2):254-60.
1997: M-Saadeh Suleiman; J J Edmond; G K Bulstrode
Calcium paradox in guinea-pig ventricular myocytes.
Experimental physiology 1997;82(4):657-64.
1997: M-Saadeh Suleiman; A C Moffatt; Walid Dihmis; Massimo Caputo; J A Hutter; Gianni Angelini; Alan J Bryan
Effect of ischaemia and reperfusion on the intracellular concentration of taurine and glutamine in the hearts of patients undergoing coronary artery surgery.
Biochimica et biophysica acta 1997;1324(2):223-31.
1997: M-Saadeh Suleiman; Walid Dihmis; Massimo Caputo; Gianni Angelini; Alan J Bryan
Changes in myocardial concentration of glutamate and aspartate during coronary artery surgery.
The American journal of physiology 1997;272(3 Pt 2):H1063-9.
1996: M-Saadeh Suleiman; Walid Dihmis; Massimo Caputo; Gianni Angelini; J A Hutter; Alan J Bryan
Changes in the intracellular concentration of myocardial glutamine in patients undergoing coronary artery bypass surgery using crystalloid and blood cardioplegia.
Biochemical Society transactions 1996;24(3):487S.
1996: J M Carter; N J Bell; M-Saadeh Suleiman
The use of Langendorff perfused guinea-pig heart to study the efflux of amino acids from heart cells.
Biochemical Society transactions 1996;24(3):482S.
1996: M-Saadeh Suleiman; D Wallace; S Birkett; Gianni Angelini
Changes in the intracellular free amino acid pool in human saphenous vein tissue culture.
Experimental physiology 1996;81(3):435-46.
1995: M-Saadeh Suleiman; D Wallace; S Birkett; Gianni Angelini
Changes in intracellular concentration of amino acids in human saphenous vein during preparation for coronary artery bypass grafting.
Cardiovascular research 1995;30(5):747-54.
1994: M-Saadeh Suleiman
New concepts in the cardioprotective action of magnesium and taurine during the calcium paradox and ischaemia of the heart.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 1994;7(3-4):295-312.
1994: K K Minezaki; M-Saadeh Suleiman; R A Chapman
Changes in mitochondrial function induced in isolated guinea-pig ventricular myocytes by calcium overload.
The Journal of physiology 1994;476(3):459-71.
1994: M-Saadeh Suleiman; K K Minezaki; K Ban; R A Chapman
A phospholipase A2 inhibitor (Ro 31-4493) prevents protein loss associated with the calcium paradox in isolated guinea pig hearts without effect on contracture, calcium overload, or the currents through L-type calcium channels.
Cardiovascular research 1994;28(5):650-5.
1993: M-Saadeh Suleiman; R A Chapman
Changes in the principal free intracellular amino acids in the Langendorff perfused guinea pig heart during arrest with calcium-free or high potassium media.
Cardiovascular research 1993;27(10):1810-4.
1993: M-Saadeh Suleiman; R A Chapman
Calcium paradox in newborn and adult guinea-pig hearts: changes in intracellular taurine and the effects of extracellular magnesium.
Experimental physiology 1993;78(4):503-16.
1993: M-Saadeh Suleiman; H C Fernando; Walid Dihmis; J A Hutter; R A Chapman
A loss of taurine and other amino acids from ventricles of patients undergoing bypass surgery.
British heart journal 1993;69(3):241-5.
1993: R A Chapman; M-Saadeh Suleiman; Y E Earm
Taurine and the heart.
Cardiovascular research 1993;27(3):358-63.
1992: M-Saadeh Suleiman; G C Rodrigo; R A Chapman
Interdependence of intracellular taurine and sodium in guinea pig heart.
Cardiovascular research 1992;26(9):897-905.
1991: R A Chapman; M-Saadeh Suleiman; G C Rodrigo; J Tunstall
The calcium paradox: a role for [Na]i, a cellular or tissue basis, a property unique to the Langendorff perfused heart? A bundle of contradictions!
Journal of molecular and cellular cardiology 1991;23(6):773-7.