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Pascal Bonaventure

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Pascal Bonaventure; Nicholas I Carruthers; Wenying Chai; Peter De Boer; Jianing Di; Wilhelmus Drinkenburg; Christine Dugovic; Curt A Dvorak; Lisa Dvorak; Ian Fraser; Michelle Kramer; Brian Lord; Diane Nepomuceno; Steve Sands; Jonathan Shelton; Jaskaran Singh; Sue Wilson; Abdellah Ahnaou; Leah Aluisio; Kirk Bertelsen; Timothy W Lovenberg
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.
Lily Alvarez-Jaimes; Miroslav Cik; S Timothy Motley; Diane Nepomuceno; James R Shoblock; Emily Stocking; Steven W Sutton; Pascal Bonaventure
In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
Da-Thao Tran; Pascal Bonaventure; Nicholas Carruthers; Curt Dvorak; Michael Hack; Michael Letavic; Timothy Lovenberg; Taraneh Mirzadegan; Steven W Sutton
Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists.

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2012: Pascal Bonaventure; Nicholas I Carruthers; Wenying Chai; Peter De Boer; Jianing Di; Wilhelmus Drinkenburg; Christine Dugovic; Curt A Dvorak; Lisa Dvorak; Ian Fraser; Michelle Kramer; Brian Lord; Diane Nepomuceno; Steve Sands; Jonathan Shelton; Jaskaran Singh; Sue Wilson; Abdellah Ahnaou; Leah Aluisio; Kirk Bertelsen; Timothy W Lovenberg
Translational evaluation of JNJ-18038683, a 5-hydroxytryptamine type 7 receptor antagonist, on rapid eye movement sleep and in major depressive disorder.
The Journal of pharmacology and experimental therapeutics 2012;342(2):429-40.
2012: Lily Alvarez-Jaimes; Miroslav Cik; S Timothy Motley; Diane Nepomuceno; James R Shoblock; Emily Stocking; Steven W Sutton; Pascal Bonaventure
In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
PloS one 2012;7(2):e30792.
2011: Da-Thao Tran; Pascal Bonaventure; Nicholas Carruthers; Curt Dvorak; Michael Hack; Michael Letavic; Timothy Lovenberg; Taraneh Mirzadegan; Steven W Sutton
Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists.
European journal of pharmacology 2011;667(1-3):120-8.
2011: Devin M Swanson; Victoria D Wong; John R Atack; Pascal Bonaventure; Curt A Dvorak; Lisa K Dvorak; JIll Jablonowski; Timothy W Lovenberg; Kirsten Morton; Diane Nepomuceno; Dale A Rudolph; Mark Seierstad; Chandra Shah; Nicholas I Carruthers
The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y₂ receptor.
Bioorganic & medicinal chemistry letters 2011;21(18):5552-6.
2011: Andrea Cippitelli; Lindsay Eisenberg; Markus Heilig; Edward D Levin; Timothy W Lovenberg; S Timothy Motley; Amir H Rezvani; J Elliott Robinson; Pascal Bonaventure; Annika Thorsell
The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.
Alcohol (Fayetteville, N.Y.) 2011;45(6):567-76.
2011: James R Shoblock; Natalie Welty; Leah Aluisio; Ian Fraser; S Timothy Motley; Kirsten Morton; James Palmer; Pascal Bonaventure; Nicholas I Carruthers; Timothy W Lovenberg; Jamin Boggs; Ruggero Galici
Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.
Psychopharmacology 2011;215(1):191-203.
2011: Ruggero Galici; Amir H Rezvani; Leah Aluisio; Brian Lord; Edward D Levin; Ian Fraser; Jamin Boggs; Natalie Welty; James R Shoblock; S Timothy Motley; Michael A Letavic; Nicholas I Carruthers; Christine Dugovic; Timothy W Lovenberg; Pascal Bonaventure
JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats.
Psychopharmacology 2011;214(4):829-41.
2011: Pascal Bonaventure; Ian C Fraser; Leah Aluisio; Jamin D Boggs; Brian Lord; Timothy W Lovenberg; James R Shoblock; Ruggero Galici
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission.
PloS one 2011;6(6):e20210.
2011: Dale A Rudolph; Curt A Dvorak; Lisa Dvorak; Diane Nepomuceno; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.
Bioorganic & medicinal chemistry letters 2011;21(1):42-4.
2010: Craig M Smith; Pei-Juan Shen; Avantika Banerjee; Pascal Bonaventure; Sherie Ma; Ross A D Bathgate; Steven W Sutton; Andrew L Gundlach
Distribution of relaxin-3 and RXFP3 within arousal, stress, affective, and cognitive circuits of mouse brain.
The Journal of comparative neurology 2010;518(19):4016-45.
2010: Michael A Letavic; Leah Aluisio; John R Atack; Pascal Bonaventure; Nicholas I Carruthers; Christine Dugovic; Anita Everson; Mark A Feinstein; Ian C Fraser; Kenway Hoey; Xiaohui Jiang; John M Keith; Tatiana Koudriakova; Perry Leung; Brian Lord; Timothy W Lovenberg; Kiev S Ly; Kirsten L Morton; S Timothy Motley; Diane Nepomuceno; Michele Rizzolio; Raymond Rynberg; Kia Sepassi; Jonathan Shelton
Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.
Bioorganic & medicinal chemistry letters 2010;20(14):4210-4.
2010: Diane Nepomuceno; Steve Sutton; Jingxue Yu; Jessica Zhu; Changlu Liu; Timothy W Lovenberg; Pascal Bonaventure
Mutagenesis studies of neuropeptide S identify a suitable peptide tracer for neuropeptide S receptor binding studies and peptides selectively activating the I(107) variant of human neuropeptide S receptor.
European journal of pharmacology 2010;635(1-3):27-33.
2010: Emily M Stocking; Leah Aluisio; John R Atack; Pascal Bonaventure; Nicholas I Carruthers; Christine Dugovic; Anita Everson; Ian Fraser; Xiaohui Jiang; Perry Leung; Brian Lord; Kiev S Ly; Kirsten L Morton; Diane Nepomuceno; Chandravadan R Shah; Jonathan Shelton; Akinola Soyode-Johnson; Michael A Letavic
Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.
Bioorganic & medicinal chemistry letters 2010;20(9):2755-60.
2010: James R Shoblock; Natalie Welty; Diane Nepomuceno; Brian Lord; Leah Aluisio; Ian Fraser; S Timothy Motley; Steve W Sutton; Kirsten Morton; Ruggero Galici; John R Atack; Lisa Dvorak; Devin M Swanson; Nicholas I Carruthers; Curt Dvorak; Timothy W Lovenberg; Pascal Bonaventure
In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor.
Psychopharmacology 2010;208(2):265-77.
2010: Fuqu Yu; Pascal Bonaventure; Robin Thurmond
The future antihistamines: histamine H3 and H4 receptor ligands.
Advances in experimental medicine and biology 2010;709():125-40.
2010: Emily M Stocking; Michael A Letavic; Pascal Bonaventure; Nicholas I Carruthers
Exploration of structure-activity relationships for dual serotonin transporter reuptake inhibitors-histamine H3 receptor antagonists.
Current topics in medicinal chemistry 2010;10(5):596-616.
2009: Devin M Swanson; Chandra R Shah; Brian Lord; Kirsten Morton; Lisa K Dvorak; Curt Mazur; Richard Apodaca; Wei Xiao; Jamin D Boggs; Mark Feinstein; Sandy J Wilson; Ann J Barbier; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.
European journal of medicinal chemistry 2009;44(11):4413-25.
2009: Curt A Dvorak; Richard Apodaca; Wei Xiao; JIll Jablonowski; Pascal Bonaventure; Christine Dugovic; Jonathan Shelton; Brian Lord; Kirsten Miller; Lisa K Dvorak; Timothy W Lovenberg; Nicholas I Carruthers
Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.
European journal of medicinal chemistry 2009;44(10):4098-106.
2009: Ruggero Galici; Jamin D Boggs; Leah Aluisio; Ian C Fraser; Pascal Bonaventure; Brian Lord; Timothy W Lovenberg
JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.
Neuropharmacology 2009;56(8):1131-7.
2009: Steven W Sutton; Jonathan Shelton; Craig Smith; John Williams; su jin yun; Timothy Motley; Chester Kuei; Pascal Bonaventure; Andrew L Gundlach; Changlu Liu; Timothy W Lovenberg
Metabolic and neuroendocrine responses to RXFP3 modulation in the central nervous system.
Annals of the New York Academy of Sciences 2009;1160():242-9.
2009: Andrew L Gundlach; Sherie Ma; Qian Sang; Pei-Juan Shen; Loretta Piccenna; Katayoun Sedaghat; Craig M Smith; Ross A D Bathgate; Andrew J Lawrence; Geoffrey W Tregear; John D Wade; David Finkelstein; Pascal Bonaventure; Changlu Liu; Timothy W Lovenberg; Steven W Sutton
Relaxin family peptides and receptors in mammalian brain.
Annals of the New York Academy of Sciences 2009;1160():226-35.
2009: Changlu Liu; Chester Kuei; Steven Sutton; Jonathan Shelton; Jessica Zhu; Diane Nepomuceno; Mohammed Akhter Hossain; John D Wade; Ross A D Bathgate; Pascal Bonaventure; Timothy W Lovenberg
Probing the functional domains of relaxin-3 and the creation of a selective antagonist for RXFP3/GPCR135 over relaxin receptor RXFP1/LGR7.
Annals of the New York Academy of Sciences 2009;1160():31-7.
2009: Jonathan Shelton; Pascal Bonaventure; Xiaorong Li; su jin yun; Timothy W Lovenberg; Christine Dugovic
5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor.
Neuropharmacology 2009;56(2):448-54.
2008: Michael A Letavic; John M Keith; Kiev S Ly; Pascal Bonaventure; Mark A Feinstein; Brian Lord; Kirsten L Miller; S Timothy Motley; Diane Nepomuceno; Steven W Sutton; Nicholas I Carruthers
2-Aryloxymethylmorpholine histamine H(3) antagonists.
Bioorganic & medicinal chemistry letters 2008;18(21):5796-9.
2008: Jessica Zhu; Chester Kuei; Steven Sutton; Fredrik Kamme; Jingxue Yu; Pascal Bonaventure; John R Atack; Timothy W Lovenberg; Changlu Liu
Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).
European journal of pharmacology 2008;590(1-3):43-52.
2008: Brock T Shireman; Curt A Dvorak; Dale A Rudolph; Pascal Bonaventure; Diane Nepomuceno; Lisa Dvorak; Kirsten L Miller; Timothy W Lovenberg; Nicholas I Carruthers
2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists.
Bioorganic & medicinal chemistry letters 2008;18(6):2103-8.
2008: Ruggero Galici; Jamin D Boggs; Kirsten L Miller; Pascal Bonaventure; John R Atack
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity.
Behavioural pharmacology 2008;19(2):153-9.
2008: Kiev S Ly; Michael A Letavic; John M Keith; Jennifer M Miller; Emily M Stocking; Ann J Barbier; Pascal Bonaventure; Brian Lord; Xiaohui Jiang; Jamin D Boggs; Lisa Dvorak; Kirsten L Miller; Diane Nepomuceno; Sandy J Wilson; Nicholas I Carruthers
Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(1):39-43.
2007: Ann J Barbier; Leah Aluisio; Brian Lord; Ying Qu; Sandy J Wilson; Jamin D Boggs; Pascal Bonaventure; Kirsten Miller; Ian Fraser; Lisa Dvorak; Cindy Pudiak; Christine Dugovic; Jonathan Shelton; Curt Mazur; Michael A Letavic; Nicholas I Carruthers; Timothy W Lovenberg
Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.
European journal of pharmacology 2007;576(1-3):43-54.
2007: Michael A Letavic; Emily M Stocking; Ann J Barbier; Pascal Bonaventure; Jamin D Boggs; Brian Lord; Kirsten L Miller; Sandy J Wilson; Nicholas I Carruthers
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(17):4799-803.
2007: Chester Kuei; Steven Sutton; Pascal Bonaventure; Cindy Pudiak; Jonathan Shelton; Jessica Zhu; Diane Nepomuceno; Jiejun Wu; Jingcai Chen; Fredrik Kamme; Mark Seierstad; Michael D Hack; Ross A D Bathgate; Mohammed Akhter Hossain; John D Wade; John Atack; Timothy W Lovenberg; Changlu Liu
R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization.
The Journal of biological chemistry 2007;282(35):25425-35.
2007: Pascal Bonaventure; Lisa Kelly; Leah Aluisio; Jonathan Shelton; Brian Lord; Ruggero Galici; Kirsten Miller; John Atack; Timothy W Lovenberg; Christine Dugovic
Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents.
The Journal of pharmacology and experimental therapeutics 2007;321(2):690-8.
2007: Pascal Bonaventure; Michael A Letavic; Christine Dugovic; S Wilson; Leah Aluisio; Cindy Pudiak; Brian Lord; Curt Mazur; Fredrik Kamme; S Nishino; Nicholas I Carruthers; Timothy W Lovenberg
Histamine H3 receptor antagonists: from target identification to drug leads.
Biochemical pharmacology 2007;73(8):1084-96.
2007: Michael A Letavic; John M Keith; JIll Jablonowski; Emily M Stocking; Leslie A Gomez; Kiev S Ly; Jennifer M Miller; Ann J Barbier; Pascal Bonaventure; Jamin D Boggs; Sandy J Wilson; Kirsten L Miller; Brian Lord; Heather M McAllister; D J Tognarelli; Jiejun Wu; Marta C Abad; Carsten Schubert; Timothy W Lovenberg; Nicholas I Carruthers
Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(4):1047-51.
2007: Sherie Ma; Pascal Bonaventure; Tania Ferraro; Pei-Juan Shen; Tanya C D Burazin; Ross A D Bathgate; Changlu Liu; Geoffrey W Tregear; Steven W Sutton; Andrew L Gundlach
Relaxin-3 in GABA projection neurons of nucleus incertus suggests widespread influence on forebrain circuits via G-protein-coupled receptor-135 in the rat.
Neuroscience 2007;144(1):165-90.
2005: Changlu Liu; Pascal Bonaventure; Steven W Sutton; Jingcai Chen; Chester Kuei; Diane Nepomuceno; Timothy W Lovenberg
Recent progress in relaxin-3-related research.
Annals of the New York Academy of Sciences 2005;1041():47-60.
2005: Pascal Bonaventure; Diane Nepomuceno; Kirsten Miller; Jingcai Chen; Chester Kuei; Fredrik Kamme; Da-Thao Tran; Timothy W Lovenberg; Changlu Liu
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog.
European journal of pharmacology 2005;513(3):181-92.
2005: Changlu Liu; Chester Kuei; Steven Sutton; Jingcai Chen; Pascal Bonaventure; Jiejun Wu; Diane Nepomuceno; Fredrik Kamme; Da-Thao Tran; Jessica Zhu; Tracey Wilkinson; Ross A D Bathgate; Elo Eriste; Rannar Sillard; Timothy W Lovenberg
INSL5 is a high affinity specific agonist for GPCR142 (GPR100).
The Journal of biological chemistry 2005;280(1):292-300.
2005: Steven W Sutton; Pascal Bonaventure; Chester Kuei; Diane Nepomuceno; Jiejun Wu; Jessica Zhu; Timothy W Lovenberg; Changlu Liu
G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: further support that relaxin-3 is the physiological ligand for GPCR135.
Neuroendocrinology 2005;82(3-4):139-50.
2005: Changlu Liu; Jingcai Chen; Chester Kuei; Steven Sutton; Diane Nepomuceno; Pascal Bonaventure; Timothy W Lovenberg
Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.
Molecular pharmacology 2005;67(1):231-40.
2005: Jingcai Chen; Chester Kuei; Steven W Sutton; Pascal Bonaventure; Diane Nepomuceno; Elo Eriste; Rannar Sillard; Timothy W Lovenberg; Changlu Liu
Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species.
The Journal of pharmacology and experimental therapeutics 2005;312(1):83-95.
2004: Peter B Hedlund; Lisa Kelly; Curt Mazur; Timothy W Lovenberg; J Gregor Sutcliffe; Pascal Bonaventure
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.
European journal of pharmacology 2004;487(1-3):125-32.
2004: JIll Jablonowski; Wenying Chai; Xiaobing Li; Dale A Rudolph; William V Murray; Mark A Youngman; Scott L Dax; Diane Nepomuceno; Pascal Bonaventure; Timothy W Lovenberg; Nicholas I Carruthers
Novel non-peptidic neuropeptide Y Y2 receptor antagonists.
Bioorganic & medicinal chemistry letters 2004;14(5):1239-42.
2004: Pascal Bonaventure; Diane Nepomuceno; Curt Mazur; Brian Lord; Dale A Rudolph; JIll Jablonowski; Nicholas I Carruthers; Timothy W Lovenberg
Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1130-7.
2004: Steven W Sutton; Pascal Bonaventure; Chester Kuei; Barbara Roland; Jingcai Chen; Diane Nepomuceno; Timothy W Lovenberg; Changlu Liu
Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing.
Neuroendocrinology 2004;80(5):298-307.
2004: Pascal Bonaventure; Diane Nepomuceno; L Hein; J Gregor Sutcliffe; Timothy W Lovenberg; Peter B Hedlund
Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine(7) receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino)tetralin interaction with alpha(2) adrenergic receptors.
Neuroscience 2004;124(4):901-11.
2002: Pascal Bonaventure; Hongqing Guo; Bin Tian; Xuejun Liu; Anton Bittner; Barbara Roland; Ranelle Salunga; Xiao-Jun Ma; Fredrik Kamme; Bernhard Meurers; Margot Bakker; Mirek Jurzak; Josée E Leysen; Mark G Erlander
Nuclei and subnuclei gene expression profiling in mammalian brain.
Brain research 2002;943(1):38-47.
2002: Pascal Bonaventure; Diane Nepomuceno; Annette Kwok; Wenying Chai; Xavier Langlois; René Hen; Kimberly Stark; Nicholas I Carruthers; Timothy W Lovenberg
Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice.
The Journal of pharmacology and experimental therapeutics 2002;302(1):240-8.
2000: Pascal Bonaventure; H Hall; W Gommeren; P Cras; Xavier Langlois; Mirek Jurzak; Josée E Leysen
Mapping of serotonin 5-HT(4) receptor mRNA and ligand binding sites in the post-mortem human brain.
Synapse (New York, N.Y.) 2000;36(1):35-46.
1999: Pascal Bonaventure; Lieve Umans; Margot H Bakker; P Cras; Xavier Langlois; Walter H M L Luyten; Anton Megens; Lutgarde Serneels; Fred Van Leuven; Josée E Leysen
Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.
Molecular pharmacology 1999;56(1):54-67.
1998: Pascal Bonaventure; Xavier Langlois; Josée E Leysen
Co-localization of 5-HT1B- and 5-HT1D receptor mRNA in serotonergic cell bodies in guinea pig dorsal raphé nucleus: a double labeling in situ hybridization histochemistry study.
Neuroscience letters 1998;254(2):113-6.
1998: Pascal Bonaventure; Pieter Voorn; Walter H M L Luyten; Josée E Leysen
5HT1B and 5HT1D receptor mRNA differential co-localization with peptide mRNA in the guinea pig trigeminal ganglion.
Neuroreport 1998;9(4):641-5.
1998: Stefan Masure; Miroslav Cik; Menelas Pangalos; Pascal Bonaventure; Peter Verhasselt; Anne Lesage; Josée E Leysen; RD Gordon
Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFRalpha-3).
European journal of biochemistry / FEBS 1998;251(3):622-30.
1998: Pascal Bonaventure; Pieter Voorn; Walter H M L Luyten; Mirek Jurzak; A Schotte; Josée E Leysen
Detailed mapping of serotonin 5-HT1B and 5-HT1D receptor messenger RNA and ligand binding sites in guinea-pig brain and trigeminal ganglion: clues for function.
Neuroscience 1998;82(2):469-84.
1997: Pascal Bonaventure; A Schotte; P Cras; Josée E Leysen
Autoradiographic mapping of 5-HT1B- and 5-HT1D receptors in human brain using [3H]alniditan, a new radioligand.
Receptors & channels 1997;5(3-4):225-30.
1996: A Schotte; P F Janssen; Pascal Bonaventure; Josée E Leysen
Endogenous dopamine limits the binding of antipsychotic drugs to D3 receptors in the rat brain: a quantitative autoradiographic study.
The Histochemical journal 1996;28(11):791-9.
1995: A Schotte; Pascal Bonaventure; P F Janssen; Josée E Leysen
In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: risperidone compared with antipsychotics hitherto used.
Japanese journal of pharmacology 1995;69(4):399-412.