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Daigo Sumi

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Akiko Endo; Daigo Sumi; Noriko Iwamoto; Yoshito Kumagai
Inhibition of DNA binding activity of cAMP response element-binding protein by 1,2-naphthoquinone through chemical modification of Cys-286.
Takashi Miura; Yasuhiro Shinkai; Hai-Yan Jiang; Noriko Iwamoto; Daigo Sumi; Keiko Taguchi; Masayuki Yamamoto; Hideto Jinno; Toshiko Tanaka-Kagawa; Arthur K Cho; Yoshito Kumagai
Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone.
Naoyuki Takayama; Toshiko Tanaka-Kagawa; Noriko Iwamoto; Hideto Jinno; Yasuhiro Shinkai; Daigo Sumi; Yoshito Kumagai
Peroxiredoxin 6 is a molecular target for 1,2-naphthoquinone, an atmospheric electrophile, in human pulmonary epithelial A549 cells.

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2011: Akiko Endo; Daigo Sumi; Noriko Iwamoto; Yoshito Kumagai
Inhibition of DNA binding activity of cAMP response element-binding protein by 1,2-naphthoquinone through chemical modification of Cys-286.
Chemico-biological interactions 2011;192(3):272-7.
2011: Takashi Miura; Yasuhiro Shinkai; Hai-Yan Jiang; Noriko Iwamoto; Daigo Sumi; Keiko Taguchi; Masayuki Yamamoto; Hideto Jinno; Toshiko Tanaka-Kagawa; Arthur K Cho; Yoshito Kumagai
Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone.
Chemical research in toxicology 2011;24(4):559-67.
2011: Naoyuki Takayama; Toshiko Tanaka-Kagawa; Noriko Iwamoto; Hideto Jinno; Yasuhiro Shinkai; Daigo Sumi; Yoshito Kumagai
Peroxiredoxin 6 is a molecular target for 1,2-naphthoquinone, an atmospheric electrophile, in human pulmonary epithelial A549 cells.
The Journal of toxicological sciences 2011;36(6):817-21.
2010: Daigo Sumi; Masako Akimori; Ken-Ichiro Inoue; Hirohisa Takano; Yoshito Kumagai
1,2-Naphthoquinone suppresses lipopolysaccharide-dependent activation of IKKβ/NF-κB/NO signaling: an alternative mechanism for the disturbance of inducible NO synthase-catalyzed NO formation.
The Journal of toxicological sciences 2010;35(6):891-8.
2010: Takashi Toyama; Yasuhiro Shinkai; Daigo Sumi; Yoshito Kumagai
Carbon monoxide derived from heme oxygenase-2 mediates reduction of methylmercury toxicity in SH-SY5Y cells.
Toxicology and applied pharmacology 2010;249(1):86-90.
2010: Yumi Abiko; Yasuhiro Shinkai; Daigo Sumi; Yoshito Kumagai
Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells.
The Journal of toxicological sciences 2010;35(3):419-23.
2009: Daigo Sumi; Yumiko Numasawa; Akiko Endo; Noriko Iwamoto; Yoshito Kumagai
Catechol estrogens mediated activation of Nrf2 through covalent modification of its quinone metabolite to Keap1.
The Journal of toxicological sciences 2009;34(6):627-35.
2008: Keiko Taguchi; Megumi Shimada; Sayako Fujii; Daigo Sumi; Xiaoqing Pan; Shigeru Yamano; Takahito Nishiyama; Akira Hiratsuka; Masayuki Yamamoto; Arthur K Cho; John R Froines; Yoshito Kumagai
Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells.
Free radical biology & medicine 2008;44(8):1645-55.
2007: Daigo Sumi; Yoshito Kumagai
[Chemical biology of 1,2-naphthoquinone, a novel air pollutant that affects signal transduction pathways].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007;127(12):1949-56.
2007: Takashi Toyama; Daigo Sumi; Yasuhiro Shinkai; Akira Yasutake; Keiko Taguchi; Kit I Tong; Masayuki Yamamoto; Yoshito Kumagai
Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.
Biochemical and biophysical research communications 2007;363(3):645-50.
2007: Noriko Iwamoto; Daigo Sumi; Takeshi Ishii; Koji Uchida; Arthur K Cho; John R Froines; Yoshito Kumagai
Chemical knockdown of protein-tyrosine phosphatase 1B by 1,2-naphthoquinone through covalent modification causes persistent transactivation of epidermal growth factor receptor.
The Journal of biological chemistry 2007;282(46):33396-404.
2007: Daigo Sumi; Aiko Manji; Yasuhiro Shinkai; Takashi Toyama; Yoshito Kumagai
Activation of the Nrf2 pathway, but decreased gamma-glutamylcysteine synthetase heavy subunit chain levels and caspase-3-dependent apoptosis during exposure of primary mouse hepatocytes to diphenylarsinic acid.
Toxicology and applied pharmacology 2007;223(3):218-24.
2007: Ken-Ichiro Inoue; Hirohisa Takano; Takamichi Ichinose; Shigeo Tomura; Rie Yanagisawa; Miho Sakurai; Daigo Sumi; Arthur K Cho; Kyoko Hiyoshi; Yoshito Kumagai
Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice.
Archives of toxicology 2007;81(8):575-81.
2006: Yang Sun; Daigo Sumi; Yoshito Kumagai
Serine 1179 phosphorylation of endothelial nitric oxide synthase caused by 2,4,6-trinitrotoluene through PI3K/Akt signaling in endothelial cells.
Toxicology and applied pharmacology 2006;214(1):55-60.
2006: Yasuhiro Shinkai; Daigo Sumi; Ikuo Fukami; Tetsuro Ishii; Yoshito Kumagai
Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.
FEBS letters 2006;580(7):1771-4.