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Huadong Sun

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TOP 3
Huadong Sun; K Sandy Pang
Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.
Huadong Sun; Ying-Ying Zeng; K Sandy Pang
Interplay of phase II enzymes and transporters in futile cycling: influence of multidrug resistance-associated protein 2-mediated excretion of estradiol 17beta-D-glucuronide and its 3-sulfate metabolite on net sulfation in perfused TR(-) and Wistar rat liver preparations.
Edwin Chiu Yuen Chow; Huadong Sun; Ansar A Khan; Geny M M Groothuis; K Sandy Pang
Effects of 1alpha,25-dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo.

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2010: Huadong Sun; K Sandy Pang
Physiological modeling to understand the impact of enzymes and transporters on drug and metabolite data and bioavailability estimates.
Pharmaceutical research 2010;27(7):1237-54.
2010: Huadong Sun; Ying-Ying Zeng; K Sandy Pang
Interplay of phase II enzymes and transporters in futile cycling: influence of multidrug resistance-associated protein 2-mediated excretion of estradiol 17beta-D-glucuronide and its 3-sulfate metabolite on net sulfation in perfused TR(-) and Wistar rat liver preparations.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(5):769-80.
2010: Edwin Chiu Yuen Chow; Huadong Sun; Ansar A Khan; Geny M M Groothuis; K Sandy Pang
Effects of 1alpha,25-dihydroxyvitamin D3 on transporters and enzymes of the rat intestine and kidney in vivo.
Biopharmaceutics & drug disposition 2010;31(1):91-108.
2008: K Sandy Pang; Marilyn E Morris; Huadong Sun
Formed and preformed metabolites: facts and comparisons.
The Journal of pharmacy and pharmacology 2008;60(10):1247-75.
2008: Huadong Sun; Li Zhang; Edwin Chiu Yuen Chow; Ge Lin; Zhong Zuo; K Sandy Pang
A catenary model to study transport and conjugation of baicalein, a bioactive flavonoid, in the Caco-2 cell monolayer: demonstration of substrate inhibition.
The Journal of pharmacology and experimental therapeutics 2008;326(1):117-26.
2008: Huadong Sun; Edwin Chiu Yuen Chow; Shanjun Liu; Yimin Du; K Sandy Pang
The Caco-2 cell monolayer: usefulness and limitations.
Expert opinion on drug metabolism & toxicology 2008;4(4):395-411.
2008: Huadong Sun; K Sandy Pang
Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: a theoretical study.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(1):102-23.
2007: Lichuan Liu; Huadong Sun; Wiqas Y Valji; K Sandy Pang
Transporters, enzymes, and enalapril removal in a rat (CC531-induced) liver metastatic model.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(5):G1078-88.
2006: Huadong Sun; Lichuan Liu; K Sandy Pang
Increased estrogen sulfation of estradiol 17beta-D-glucuronide in metastatic tumor rat livers.
The Journal of pharmacology and experimental therapeutics 2006;319(2):818-31.
2003: Debbie Tam; Huadong Sun; K Sandy Pang
Influence of P-glycoprotein, transfer clearances, and drug binding on intestinal metabolism in Caco-2 cell monolayers or membrane preparations: a theoretical analysis.
Drug metabolism and disposition: the biological fate of chemicals 2003;31(10):1214-26.