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Mao-Fu Sun

Research Profile

Chemicals & Drugs

Disorders

Factor XI Deficiency

Concepts & Ideas

Phenomena

Physiology

Amino Acid Substitution

Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Yipeng Geng; Anton Matafonov; James H Morrissey; Stephanie A Smith; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; Qiufang Cheng; David Gailani
The dimeric structure of factor XI and zymogen activation.
Yipeng Geng; Amanda Messer; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; S Paul Bajaj; David Gailani
A sequential mechanism for exosite-mediated factor IX activation by factor XIa.
Qiufang Cheng; Erik Tucker; Meghann S Pine; India Sisler; Anton Matafonov; Mao-Fu Sun; Tara C White-Adams; Ann Stephanie Smith; Stephen R Hanson; Owen J T McCarty; Thomas Renné; András Gruber; David Gailani
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.

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All Publications

2013: Yipeng Geng; Anton Matafonov; James H Morrissey; Stephanie A Smith; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; Qiufang Cheng; David Gailani
The dimeric structure of factor XI and zymogen activation.
Blood 2013;121(19):3962-9.
2012: Yipeng Geng; Amanda Messer; Stephen B Smith; Mao-Fu Sun; Ingrid Verhamme; S Paul Bajaj; David Gailani
A sequential mechanism for exosite-mediated factor IX activation by factor XIa.
The Journal of biological chemistry 2012;287(45):38200-9.
2010: Qiufang Cheng; Erik Tucker; Meghann S Pine; India Sisler; Anton Matafonov; Mao-Fu Sun; Tara C White-Adams; Ann Stephanie Smith; Stephen R Hanson; Owen J T McCarty; Thomas Renné; András Gruber; David Gailani
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Blood 2010;116(19):3981-9.
2010: David Gailani; Mao-Fu Sun; Qiufang Cheng; Anton Matafonov; Erik Tucker; Andras Gruber; Jonas Emsley
Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7.
Blood 2010;116(7):1185-6; author reply 1186-7.
2009: Dmitri V Kravtsov; Anton Matafonov; Erik Tucker; Mao-Fu Sun; Peter N Walsh; Andras Gruber; David Gailani
Factor XI contributes to thrombin generation in the absence of factor XII.
Blood 2009;114(2):452-8.
2009: Likui Yang; Mao-Fu Sun; David Gailani; Alireza R Rezaie
Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitor.
Biochemistry 2009;48(7):1517-24.
2008: Stephen B Smith; Ingrid Verhamme; Mao-Fu Sun; Paul E Bock; David Gailani
Characterization of Novel Forms of Coagulation Factor XIa: independence of factor XIa subunits in factor IX activation.
The Journal of biological chemistry 2008;283(11):6696-705.
2008: Amy E Schmidt; Mao-Fu Sun; Taketoshi Ogawa; S Paul Bajaj; David Gailani
Functional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa.
Biochemistry 2008;47(5):1326-35.
2007: David Gailani; A Schmidt; Mao-Fu Sun; P H Bolton-Maggs; S P Bajaj
A cross-reactive material positive variant of coagulation factor XI (FXIP520L) with a catalytic defect.
Journal of thrombosis and haemostasis : JTH 2007;5(4):781-7.
2006: Alireza R Rezaie; Mao-Fu Sun; David Gailani
Contributions of basic amino acids in the autolysis loop of factor XIa to serpin specificity.
Biochemistry 2006;45(31):9427-33.
2005: Taketoshi Ogawa; Ingrid Verhamme; Mao-Fu Sun; Paul E Bock; David Gailani
Exosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX.
The Journal of biological chemistry 2005;280(25):23523-30.
2004: Dmitri V Kravtsov; Wenman Wu; Joost C M Meijers; Mao-Fu Sun; Morey A Blinder; Thao P Dang; Hongli Wang; David Gailani
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Blood 2004;104(1):128-34.
2003: Qiufang Cheng; Mao-Fu Sun; Dmitri V Kravtsov; A Aktimur; David Gailani
Factor XI apple domains and protein dimerization.
Journal of thrombosis and haemostasis : JTH 2003;1(11):2340-7.
2001: Mao-Fu Sun; Frank A Baglia; D Ho; Danko Martincic; R E Ware; Peter N Walsh; David Gailani
Defective binding of factor XI-N248 to activated human platelets.
Blood 2001;98(1):125-9.
2001: David Gailani; D Ho; Mao-Fu Sun; Qiufang Cheng; Peter N Walsh
Model for a factor IX activation complex on blood platelets: dimeric conformation of factor XIa is essential.
Blood 2001;97(10):3117-22.
2000: DH Ho; Karen O Badellino; Frank A Baglia; Mao-Fu Sun; M M Zhao; David Gailani; Peter N Walsh
The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface.
The Journal of biological chemistry 2000;275(33):25139-45.
1999: Mao-Fu Sun; Mingming Zhao; David Gailani
Identification of amino acids in the factor XI apple 3 domain required for activation of factor IX.
The Journal of biological chemistry 1999;274(51):36373-8.
1998: Mingming Zhao; T Abdel-Razek; Mao-Fu Sun; David Gailani
Characterization of a heparin binding site on the heavy chain of factor XI.
The Journal of biological chemistry 1998;273(47):31153-9.
1998: Danko Martincic; S A Zimmerman; R E Ware; Mao-Fu Sun; James A Whitlock; David Gailani
Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting.
Blood 1998;92(9):3309-17.
1997: David Gailani; Mao-Fu Sun; Y Sun
A comparison of murine and human factor XI.
Blood 1997;90(3):1055-64.