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Shao-Cong Sun
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Chemicals & Drugs
Physiology
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Network (preview)
24
Harhaj, Edward
15
Xiao, Gutian
13
Zhang, Minying
9
Faye, Ingrid
9
Good, L
7
Reiley, William
6
Jin, Wei
6
Waterfield, Michael
6
Wu, Xuefeng
5
Wright, Ato
5
Uhlik, MT
5
Jin, Wei
5
Fong, Abraham
4
Cvijic, Mary Ellen
3
Chang, Mikyoung
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All Publications
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2009: Chang Mikyoung; Jin Wei; Sun Shao-Cong
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production.
Nature immunology 2009;10(10):1089-95.
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2009: Fontenot Danielle; He Hong; Hanabuchi Shino; Nehete Pramod N; Zhang Minying; Chang Mikyoung; Nehete Bharti; Wang Yui-Hsi; Wang Yi-Hong; Ma Zhong-Min; Lee Hai-Chon; Ziegler Steven F; Courtney Amy N; Miller Christopher J; Sun Shao-Cong; Liu Yong-Jun; Sastry K Jagannadha
TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16776-81.
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2009: Jin Wei; Zhou Xiao-Fei; Yu Jiayi; Cheng Xuhong; Sun Shao-Cong
Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.
Blood 2009;113(26):6603-10.
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2009: Zhang Minying; Jin Wei; Zhou Xiaofei; Yu Jiayi; Lee Andrew J; Sun Shao-Cong
Deregulation of Tpl2 and NF-kappaB signaling and induction of macrophage apoptosis by the anti-depressant drug lithium.
Cellular signalling 2009;21(4):559-66.
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2009: Chang Mikyoung; Lee Andrew J; Fitzpatrick Leo; Zhang Minying; Sun Shao-Cong
NF-kappa B1 p105 regulates T cell homeostasis and prevents chronic inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3131-8.
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2008: Sun Shao-Cong; Ley Steven C
New insights into NF-kappaB regulation and function.
Trends in immunology 2008;29(10):469-78.
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2008: Sun Shao-Cong
Deubiquitylation and regulation of the immune response.
Nature reviews. Immunology 2008;8(7):501-11.
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2008: Zhang Minying; Wu Xuefeng; Lee Andrew J; Jin Wei; Chang Mikyoung; Wright Ato; Imaizumi Tadaatsu; Sun Shao-Cong
Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.
The Journal of biological chemistry 2008;283(27):18621-6.
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2008: Jin Wei; Chang Mikyoung; Paul Emmanuel M; Babu Geetha; Lee Andrew J; Reiley William; Wright Ato; Zhang Minying; You Jun; Sun Shao-Cong
Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice.
The Journal of clinical investigation 2008;118(5):1858-66.
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2007: Wright Ato; Reiley William W; Chang Mikyoung; Jin Wei; Lee Andrew Joon; Zhang Minying; Sun Shao-Cong
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD.
Developmental cell 2007;13(5):705-16.
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2007: Reiley William W; Jin Wei; Lee Andrew Joon; Wright Ato; Wu Xuefeng; Tewalt Eric F; Leonard Timothy O; Norbury Christopher C; Fitzpatrick Leo; Zhang Minying; Sun Shao-Cong
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses.
The Journal of experimental medicine 2007;204(6):1475-85.
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2007: Jin Wei; Reiley William R; Lee Andrew J; Wright Ato; Wu Xuefeng; Zhang Minying; Sun Shao-Cong
Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells.
The Journal of biological chemistry 2007;282(21):15884-93.
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2007: Wu Xuefeng; Sun Shao-Cong
Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
EMBO reports 2007;8(5):510-5.
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2007: Harhaj Nicole S; Sun Shao-Cong; Harhaj Edward W
Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase.
The Journal of biological chemistry 2007;282(6):4185-92.
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2006: Liang Chunyang; Zhang Minying; Sun Shao-Cong
beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870.
Cellular signalling 2006;18(8):1309-17.
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2006: Babu Geetha; Waterfield Michael; Chang Mikyoung; Wu Xuefeng; Sun Shao-Cong
Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells.
The Journal of biological chemistry 2006;281(20):14041-7.
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2006: Reiley William W; Zhang Minying; Jin Wei; Losiewicz Mandy; Donohue Keri B; Norbury Christopher C; Sun Shao-Cong
Regulation of T cell development by the deubiquitinating enzyme CYLD.
Nature immunology 2006;7(4):411-7.
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2006: Zhang Wenyi; Hirschler-Laszkiewicz Iwona; Tong Qin; Conrad Kathleen; Sun Shao-Cong; Penn Linda; Barber Dwayne L; Stahl Richard; Carey David J; Cheung Joseph Y; Miller Barbara A
TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.
American journal of physiology. Cell physiology 2006;290(4):C1146-59.
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2006: Babu Geetha R; Jin Wei; Norman Lourdes; Waterfield Michael; Chang Mikyoung; Wu Xuefeng; Zhang Minying; Sun Shao-Cong
Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation.
Biochimica et biophysica acta 2006;1763(2):174-81.
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2005: Sun Shao-Cong; Yamaoka Shoji
Activation of NF-kappaB by HTLV-I and implications for cell transformation.
Oncogene 2005;24(39):5952-64.
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2005: Reiley William; Zhang Minying; Wu Xuefeng; Granger Erica; Sun Shao-Cong
Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation.
Molecular and cellular biology 2005;25(10):3886-95.
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2005: Harhaj Edward W; Harhaj Nicole S; Grant Christian; Mostoller Kate; Alefantis Timothy; Sun Shao-Cong; Wigdahl Brian
Human T cell leukemia virus type I Tax activates CD40 gene expression via the NF-kappa B pathway.
Virology 2005;333(1):145-58.
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2005: Morrison Matthew D; Reiley William; Zhang Minying; Sun Shao-Cong
An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.
The Journal of biological chemistry 2005;280(11):10018-24.
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2004: Reiley William; Zhang Minying; Sun Shao-Cong
Negative regulation of JNK signaling by the tumor suppressor CYLD.
The Journal of biological chemistry 2004;279(53):55161-7.
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2004: Waterfield Michael; Jin Wei; Reiley William; Zhang Minying; Sun Shao-Cong
IkappaB kinase is an essential component of the Tpl2 signaling pathway.
Molecular and cellular biology 2004;24(13):6040-8.
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2004: Xiao Gutian; Fong Abraham; Sun Shao-Cong
Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation.
The Journal of biological chemistry 2004;279(29):30099-105.
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2004: Liao Gongxian; Zhang Minying; Harhaj Edward W; Sun Shao-Cong
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation.
The Journal of biological chemistry 2004;279(25):26243-50.
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2003: Sun Shao-Cong; Xiao Gutian
Deregulation of NF-kappaB and its upstream kinases in cancer.
Cancer metastasis reviews 2003;22(4):405-22.
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2003: Cvijic Mary Ellen; Xiao Gutian; Sun Shao-Cong
Study of T-cell signaling by somatic cell mutagenesis and complementation cloning.
Journal of immunological methods 2003;278(1-2):293-304.
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2003: Liao Gongxian; Sun Shao-Cong
Regulation of NF-kappaB2/p100 processing by its nuclear shuttling.
Oncogene 2003;22(31):4868-74.
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2003: Waterfield Michael R; Zhang Minying; Norman Lourdes P; Sun Shao Cong
NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase.
Molecular cell 2003;11(3):685-94.
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2002: Fong Abraham; Zhang Minying; Neely John; Sun Shao-Cong
S9, a 19 S proteasome subunit interacting with ubiquitinated NF-kappaB2/p100.
The Journal of biological chemistry 2002;277(43):40697-702.
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2002: Fong Abraham; Sun Shao-Cong
Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100.
The Journal of biological chemistry 2002;277(25):22111-4.
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2001: Xiao G; Cvijic M E; Fong A; Harhaj E W; Uhlik M T; Waterfield M; Sun S C
Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha.
The EMBO journal 2001;20(23):6805-15.
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2001: Rivera-Walsh I; Waterfield M; Xiao G; Fong A; Sun S C
NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I Tax-induced T-cell death.
The Journal of biological chemistry 2001;276(44):40385-8.
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2001: Senftleben U; Cao Y; Xiao G; Greten F R; Krähn G; Bonizzi G; Chen Y; Hu Y; Fong A; Sun S C; Karin M
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway.
Science (New York, N.Y.) 2001;293(5534):1495-9.
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2001: Xiao G; Harhaj E W; Sun S C
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.
Molecular cell 2001;7(2):401-9.
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2000: Sun S C; Harhaj E W; Xiao G; Good L
Activation of I-kappaB kinase by the HTLV type 1 Tax protein: mechanistic insights into the adaptor function of IKKgamma.
AIDS research and human retroviruses 2000;16(16):1591-6.
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2000: Xiao G; Harhaj E W; Sun S C
Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.
The Journal of biological chemistry 2000;275(44):34060-7.
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2000: Xiao G; Sun S C
Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein.
Oncogene 2000;19(45):5198-203.
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2000: Rivera-Walsh I; Cvijic M E; Xiao G; Sun S C
The NF-kappa B signaling pathway is not required for Fas ligand gene induction but mediates protection from activation-induced cell death.
The Journal of biological chemistry 2000;275(33):25222-30.
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2000: Xiao G; Sun S C
Negative regulation of the nuclear factor kappa B-inducing kinase by a cis-acting domain.
The Journal of biological chemistry 2000;275(28):21081-5.
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2000: Harhaj E W; Good L; Xiao G; Uhlik M; Cvijic M E; Rivera-Walsh I; Sun S C
Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein.
Oncogene 2000;19(11):1448-56.
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1999: Sun S C; Ballard D W
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.
Oncogene 1999;18(49):6948-58.
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1999: Harhaj E W; Sun S C
Regulation of RelA subcellular localization by a putative nuclear export signal and p50.
Molecular and cellular biology 1999;19(10):7088-95.
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1999: Harhaj E W; Sun S C
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein.
The Journal of biological chemistry 1999;274(33):22911-4.
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1999: Sun S C; Maggirwar S B; Harhaj E W; Uhlik M
Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells.
Oncogene 1999;18(7):1401-9.
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1999: Harhaj E W; Good L; Xiao G; Sun S C
Gene expression profiles in HTLV-I-immortalized T cells: deregulated expression of genes involved in apoptosis regulation.
Oncogene 1999;18(6):1341-9.
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1998: Harhaj E W; Sun S C
IkappaB kinases serve as a target of CD28 signaling.
The Journal of biological chemistry 1998;273(39):25185-90.
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1998: Rivera I; Harhaj E W; Sun S C
Involvement of NF-AT in type I human T-cell leukemia virus Tax-mediated Fas ligand promoter transactivation.
The Journal of biological chemistry 1998;273(35):22382-8.
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1998: Uhlik M; Good L; Xiao G; Harhaj E W; Zandi E; Karin M; Sun S C
NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation.
The Journal of biological chemistry 1998;273(33):21132-6.
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1998: Zhang M Y; Harhaj E W; Bell L; Sun S C; Miller B A
Bcl-3 expression and nuclear translocation are induced by granulocyte-macrophage colony-stimulating factor and erythropoietin in proliferating human erythroid precursors.
Blood 1998;92(4):1225-34.
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1998: Zhang M Y; Sun S C; Bell L; Miller B A
NF-kappaB transcription factors are involved in normal erythropoiesis.
Blood 1998;91(11):4136-44.
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1997: Maggirwar S B; Harhaj E W; Sun S C
Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors.
Molecular and cellular biology 1997;17(5):2605-14.
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1997: Harhaj E W; Sun S C
The serine/threonine phosphatase inhibitor calyculin A induces rapid degradation of IkappaBbeta. Requirement of both the N- and C-terminal sequences.
The Journal of biological chemistry 1997;272(9):5409-12.
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1997: Good L; Maggirwar S B; Harhaj E W; Sun S C
Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells.
The Journal of biological chemistry 1997;272(3):1425-8.
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1996: Harhaj E W; Maggirwar S B; Good L; Sun S C
CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers.
Molecular and cellular biology 1996;16(12):6736-43.
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1996: Mandal M; Maggirwar S B; Sharma N; Kaufmann S H; Sun S C; Kumar R
Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway.
The Journal of biological chemistry 1996;271(48):30354-9.
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1996: Good L; Maggirwar S B; Sun S C
Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element.
The EMBO journal 1996;15(14):3744-50.
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1996: Good L F; Maggirwar S B; Kealiher A; Uhlik M; Sun S C
Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors.
Biochemical and biophysical research communications 1996;223(1):123-8.
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1996: Harhaj E W; Maggirwar S B; Sun S C
Inhibition of p105 processing by NF-kappaB proteins in transiently transfected cells.
Oncogene 1996;12(11):2385-92.
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1996: Good L; Sun S C
Persistent activation of NF-kappa B/Rel by human T-cell leukemia virus type 1 tax involves degradation of I kappa B beta.
Journal of virology 1996;70(5):2730-5.
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1996: Harhaj E; Blaney J; Millhouse S; Sun S C
Differential effects of I kappa B molecules on Tat-mediated transactivation of HIV-1 LTR.
Virology 1996;216(1):284-7.
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1995: Maggirwar S B; Harhaj E; Sun S C
Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor.
Oncogene 1995;11(5):993-8.
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1995: Sun S C; Maggirwar S B; Harhaj E
Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites.
The Journal of biological chemistry 1995;270(31):18347-51.
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1995: Sun S C; Faye I
Transcription of immune genes in the giant silkmoth, Hyalophora cecropia, is augmented by H2O2 and diminished by thiol reagents.
European journal of biochemistry / FEBS 1995;231(1):93-8.
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1995: Lindström-Dinnetz I; Sun S C; Faye I
Structure and expression of Hemolin, an insect member of the immunoglobulin gene superfamily.
European journal of biochemistry / FEBS 1995;230(3):920-5.
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1993: Engström Y; Kadalayil L; Sun S C; Samakovlis C; Hultmark D; Faye I
kappa B-like motifs regulate the induction of immune genes in Drosophila.
Journal of molecular biology 1993;232(2):327-33.
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1993: Schmidt O; Faye I; Lindström-Dinnetz I; Sun S C
Specific immune recognition of insect hemolin.
Developmental and comparative immunology 1993;17(3):195-200.
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1992: Sun S C; Faye I
Affinity purification and characterization of CIF, an insect immunoresponsive factor with NF-kappa B-like properties.
Comparative biochemistry and physiology. B, Comparative biochemistry 1992;103(1):225-33.
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1992: Sun S C; Faye I
Cecropia immunoresponsive factor, an insect immunoresponsive factor with DNA-binding properties similar to nuclear-factor kappa B.
European journal of biochemistry / FEBS 1992;204(2):885-92.
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1991: Sun S C; Asling B; Faye I
Organization and expression of the immunoresponsive lysozyme gene in the giant silk moth, Hyalophora cecropia.
The Journal of biological chemistry 1991;266(10):6644-9.
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1991: Sun S C; Lindström I; Lee J Y; Faye I
Structure and expression of the attacin genes in Hyalophora cecropia.
European journal of biochemistry / FEBS 1991;196(1):247-54.
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1990: Sun S C; Lindström I; Boman H G; Faye I; Schmidt O
Hemolin: an insect-immune protein belonging to the immunoglobulin superfamily.
Science (New York, N.Y.) 1990;250(4988):1729-32.
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