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Zhifu Sun

Research Profile

Disorders

Physiology

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Single Nucleotide Polymorphism

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John Hawse; James N Ingle; Wilma L Lingle; Kevin S Pitel; Mine S Cicek; Anne Gingery; Matthew P Goetz; Sarah B Grygo; Malayannan Subramaniam; Zhifu Sun; Xianglin Wu; Thomas C Spelsberg
Endoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogens.
Saswati Mahapatra; Zhifu Sun; Donald J Tindall; Charles Y F Young; Rafael E Jimenez; Eric W Klee; George G Klee; Krishna Vanaja Donkena
Global methylation profiling for risk prediction of prostate cancer.
Mariza de Andrade; Claude Deschamps; Ruoxiang Jiang; Yan Li; Andrew H Limper; Randolph S Marks; David E Midthun; Curtis L Olswold; Paul D Scanlon; Zhifu Sun; Stephen J Swensen; Jason A Wampfler; Julie M Cunningham; Ping Yang
Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer.

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All Publications

2013: John Hawse; James N Ingle; Wilma L Lingle; Kevin S Pitel; Mine S Cicek; Anne Gingery; Matthew P Goetz; Sarah B Grygo; Malayannan Subramaniam; Zhifu Sun; Xianglin Wu; Thomas C Spelsberg
Endoxifen's molecular mechanisms of action are concentration dependent and different than that of other anti-estrogens.
PloS one 2013;8(1):e54613.
2012: Saswati Mahapatra; Zhifu Sun; Donald J Tindall; Charles Y F Young; Rafael E Jimenez; Eric W Klee; George G Klee; Krishna Vanaja Donkena
Global methylation profiling for risk prediction of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(10):2882-95.
2012: Mariza de Andrade; Claude Deschamps; Ruoxiang Jiang; Yan Li; Andrew H Limper; Randolph S Marks; David E Midthun; Curtis L Olswold; Paul D Scanlon; Zhifu Sun; Stephen J Swensen; Jason A Wampfler; Julie M Cunningham; Ping Yang
Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer.
Cancer prevention research (Philadelphia, Pa.) 2012;5(3):365-73.
2012: Nifang Niu; Daniel J Schaid; Zhifu Sun; Ping Yang; Ryan P Abo; Anthony Batzler; Abra G Brisbin; Julie M Cunningham; Qiping Feng; Brooke L Fridley; Gregory Jenkins; Krishna Kalari; Liang Li; Liewei Wang
Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.
BMC cancer 2012;12():422.
2012: Brooke L Fridley; Yan Asmann; Jill Barnholtz-Sloan; Prabhakar Chalise; Julie M Cunningham; David Fenstermacher; Edwin S Iversen; Melissa C Larson; Catherine M Phelan; Harvey A Risch; Joellen M Schildkraut; Thomas A Sellers; Zhifu Sun; Rebecca Sutphen; Ya-Yu Tsai; Robert A Vierkant; Ellen L Goode
Germline copy number variation and ovarian cancer survival.
Frontiers in genetics 2012;3():142.
2012: Krishna R Kalari; Jean-Pierre Kocher; Alexey A Leontovich; Asha Nair; Brian M Necela; Edith A Perez; David N Reisman; David Rossell; Zhifu Sun; Xiaojia Tang; Yan W Asmann; Saurabh Baheti; Tiffany Baker; Jennifer M Carr; High-Seng Chai; Alan P Fields; Steven N Hart; Asif Hossain; Jennifer M Kachergus; Michael P Walsh; Curtis S Younkin; E Aubrey Thompson
Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations.
Frontiers in oncology 2012;2():12.
2011: Ju Dong Yang; In-Sun Chu; Yong Hoon Kim; Ju Seog Lee; Sun-Hee Leem; Lewis R Roberts; So-Young Seol; Zhifu Sun; Snorri S Thorgeirsson; Koo Jeong Kang
Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling.
Journal of Korean medical science 2011;26(11):1428-38.
2011: Yafei Li; Zhifu Sun; Julie M Cunningham; Marie-Christine Aubry; Jason A Wampfler; Gary A Croghan; Cassandra Johnson; Danli Wu; Jeremiah A Aakre; Julian Molina; Liewei Wang; V Shane Pankratz; Ping Yang
Genetic variations in multiple drug action pathways and survival in advanced stage non-small cell lung cancer treated with chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(11):3830-40.
2011: Ju Dong Yang; Zhifu Sun; Chunling Hu; Jinping Lai; Rebecca Dove; Ikuo Nakamura; Ju-Seog Lee; Snorri S Thorgeirsson; Koo Jeong Kang; In-Sun Chu; Lewis Roberts
Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
Genes, chromosomes & cancer 2011;50(2):122-35.
2011: Xianglin Wu; Matthew P Goetz; Sarah B Grygo; James N Ingle; Wilma L Lingle; Vivian C Negron; Thomas C Spelsberg; Malayannan Subramaniam; Zhifu Sun; John Hawse
Estrogen receptor-beta sensitizes breast cancer cells to the anti-estrogenic actions of endoxifen.
Breast cancer research : BCR 2011;13(2):R27.
2011: Guerard W Byrne; Zeji Du; Zhifu Sun; Yan W Asmann; Christopher G A McGregor
Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation.
Xenotransplantation 2011;18(1):14-27.
2010: Zhifu Sun; Junjie Chen; J Aakre; Randolph S Marks; Y Y Garces; R Jiang; O Idowu; Julie M Cunningham; Y Liu; V Shane Pankratz; Ping Yang
Genetic variation in glutathione metabolism and DNA repair genes predicts survival of small-cell lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(10):2011-6.
2010: Yafei Li; Zhifu Sun; Yanhong Wu; Dusica Babovic-Vuksanovic; Yan Li; Julie M Cunningham; Vernon S Pankratz; Ping Yang
Cystic fibrosis transmembrane conductance regulator gene mutation and lung cancer risk.
Lung cancer (Amsterdam, Netherlands) 2010;70(1):14-21.
2010: Gail Stilling; Zhifu Sun; Shuya Zhang; Long Jin; Alberto Righi; Gábor Kovācs; Marta Korbonits; Bernd W Scheithauer; Kalman Kovacs; Ricardo V Lloyd
MicroRNA expression in ACTH-producing pituitary tumors: up-regulation of microRNA-122 and -493 in pituitary carcinomas.
Endocrine 2010;38(1):67-75.
2010: Yafei Li; Chau-Chyun Sheu; Yuanqing Ye; Mariza de Andrade; Liang Wang; Shen-Chih Chang; Marie C Aubry; Jeremiah A Aakre; Mark S Allen; Feng Chen; Julie M Cunningham; Claude Deschamps; Ruoxiang Jiang; Jie Lin; Randolph S Marks; V Shane Pankratz; Li Su; Yan Li; Zhifu Sun; Hui Tang; George Vasmatzis; Curtis C Harris; Margaret R Spitz; Jin Jen; Renyi Wang; Zuo-Feng Zhang; David C Christiani; Xifeng Wu; Ping Yang
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.
The lancet oncology 2010;11(4):321-30.
2009: Lucy J Schmidt; Kevin M Regan; S Keith Anderson; Zhifu Sun; Karla V Ballman; Donald J Tindall
Effects of the 5 alpha-reductase inhibitor dutasteride on gene expression in prostate cancer xenografts.
The Prostate 2009;69(16):1730-43.
2009: Jin C Tomshine; Sandra R Severson; Dennis A Wigle; Zhifu Sun; Daniah A T Beleford; Viji Shridhar; Bruce F Horazdovsky
Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.
The Journal of biological chemistry 2009;284(39):26331-9.
2009: Ping Yang; Sumithra J Mandrekar; Shauna H Hillman; Katie L Allen Ziegler; Zhifu Sun; Jason A Wampfler; Julie M Cunningham; Jeff A Sloan; Alex A. Adjei; Edith Perez; James R Jett
Evaluation of glutathione metabolic genes on outcomes in advanced non-small cell lung cancer patients after initial treatment with platinum-based chemotherapy: an NCCTG-97-24-51 based study.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(4):479-85.
2009: Eric W Klee; Sibel Erdogan; Lori Tillmans; Farhad Kosari; Zhifu Sun; Dennis Wigle; Ping Yang; Marie-Christine Aubry; George Vasmatzis
Impact of sample acquisition and linear amplification on gene expression profiling of lung adenocarcinoma: laser capture micro-dissection cell-sampling versus bulk tissue-sampling.
BMC medical genomics 2009;2():13.
2008: Ping Yang; Zhifu Sun; Michael J Krowka; Marie-Christine Aubry; William R Bamlet; Jason A Wampfler; Stephen N Thibodeau; Jerry A Katzmann; Mark S Allen; David E Midthun; Randolph S Marks; Mariza de Andrade
Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk.
Archives of internal medicine 2008;168(10):1097-103.
2008: Zhifu Sun; Dennis Wigle; Ping Yang
Non-overlapping and non-cell-type-specific gene expression signatures predict lung cancer survival.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(6):877-83.
2007: Elizabeth J Atkinson; Brooke L Fridley; Ellen L Goode; Shannon K McDonnell; Wen Liu; Kari G Rabe; Zhifu Sun; Susan L Slager; Mariza de Andrade
Linkage analysis using principal components of gene expression data.
BMC proceedings 2007;1 Suppl 1():S79.
2007: Ellen L Goode; Brooke L Fridley; Zhifu Sun; Elizabeth J Atkinson; Alex S Nord; Shannon K McDonnell; Gail P Jarvik; Mariza de Andrade; Susan L Slager
Comparison of tagging single-nucleotide polymorphism methods in association analyses.
BMC proceedings 2007;1 Suppl 1():S6.
2007: Mariza de Andrade; Elizabeth J Atkinson; Brooke L Fridley; Ellen L Goode; Shannon K McDonnell; Wen Liu; Kari G Rabe; Zhifu Sun; Susan L Slager
The genetics of gene expression: comparison of linkage scans using two phenotype normalization methods.
BMC proceedings 2007;1 Suppl 1():S151.
2007: Wen Liu; Zhifu Sun; William R Bamlet; Elizabeth J Atkinson; Brooke L Fridley; Susan L Slager; Mariza de Andrade; Ellen L Goode
Analysis of variation in NF-kappaB genes and expression levels of NF-kappaB-regulated molecules.
BMC proceedings 2007;1 Suppl 1():S126.
2006: Zhifu Sun; Ping Yang
Gene expression profiling on lung cancer outcome prediction: present clinical value and future premise.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(11):2063-8.
2004: Zhifu Sun; Ping Yang; Marie-Christine Aubry; Farhad Kosari; Chiaki Endo; Julian Molina; George Vasmatzis
Can gene expression profiling predict survival for patients with squamous cell carcinoma of the lung?
Molecular cancer 2004;3(1):35.
2004: Zhifu Sun; Ping Yang
Role of imbalance between neutrophil elastase and alpha 1-antitrypsin in cancer development and progression.
The lancet oncology 2004;5(3):182-90.