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Roger Sunahara

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Ka Young Chung; Peter W Day; Roger K Sunahara; Gisselle Vélez-Ruiz; Brian K Kobilka
Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach.
Gregory Collins; Remy L Brim; Nicholas W Lukacs; Diwahar Narasimhan; Kathleen R Noon; Roger K Sunahara; James H Woods; Mei-Chuan Ko
Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys.
Aashish Manglik; Jesper M Mathiesen; Leonardo Pardo; Roger K Sunahara; Foon Sun Thian; William I Weis; Brian K Kobilka; Tong Sun Kobilka; Andrew C Kruse; Sébastien Granier
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.

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2013: Ka Young Chung; Peter W Day; Roger K Sunahara; Gisselle Vélez-Ruiz; Brian K Kobilka
Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach.
PloS one 2013;8(1):e54942.
2012: Gregory Collins; Remy L Brim; Nicholas W Lukacs; Diwahar Narasimhan; Kathleen R Noon; Roger K Sunahara; James H Woods; Mei-Chuan Ko
Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2012;342(1):205-13.
2012: Aashish Manglik; Jesper M Mathiesen; Leonardo Pardo; Roger K Sunahara; Foon Sun Thian; William I Weis; Brian K Kobilka; Tong Sun Kobilka; Andrew C Kruse; Sébastien Granier
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.
Nature 2012;485(7398):321-6.
2012: Tien-Yi Lee; Yoon Shin Park; Roger K Sunahara; James H Woods; George A Garcia; Victor C Yang
Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination.
Molecular pharmaceutics 2012;9(5):1361-73.
2012: Gregory Collins; Alyssa R Cunningham; Mei-Chuan Ko; Diwahar Narasimhan; Joseph Nichols; Roger K Sunahara; Matthew E Zaks; James H Woods
Long-lasting effects of a PEGylated mutant cocaine esterase (CocE) on the reinforcing and discriminative stimulus effects of cocaine in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(5):1092-103.
2012: Diwahar Narasimhan; James H Woods; Roger K Sunahara
Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction.
Future medicinal chemistry 2012;4(2):137-50.
2012: Remy L Brim; Diwa Narasimhan; Gregory T Collins; James H Woods; Joseph Nichols; Kathleen R Noon; Mei-Chuan Ko; Aron Stein; Roger K Sunahara
The fate of bacterial cocaine esterase (CocE): an in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination.
The Journal of pharmacology and experimental therapeutics 2012;340(1):83-95.
2011: Remy L Brim; Diwahar Narasimhan; Joseph Nichols; Kathleen R Noon; James H Woods; Roger K Sunahara
Evaluation of the hydrolytic activity of a long-acting mutant bacterial cocaine in the presence of commonly co-administered drugs.
Drug and alcohol dependence 2011;119(3):224-8.
2011: Diwahar Narasimhan; Joseph Nichols; John J G Tesmer; James H Woods; Jimmy Chan; Gregory Collins; Elin Edwald; Mei-Chuan Ko; Mark R Nance; Roger K Sunahara
Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Molecular pharmacology 2011;80(6):1056-65.
2011: Remy L Brim; Gregory Collins; Diwahar Narasimhan; Joseph Nichols; Kathleen R Noon; Roger K Sunahara; James H Woods
The ability of bacterial cocaine esterase to hydrolyze cocaine metabolites and their simultaneous quantification using high-performance liquid chromatography-tandem mass spectrometry.
Molecular pharmacology 2011;80(6):1119-27.
2011: Gregory Collins; Alyssa R Cunningham; Mei-Chuan Ko; Diwahar Narasimhan; Joseph Nichols; Carley St Clair; Roger K Sunahara; Matthew E Zaks; James H Woods
Effects of a long-acting mutant bacterial cocaine esterase on acute cocaine toxicity in rats.
Drug and alcohol dependence 2011;118(2-3):158-65.
2011: Ka Young Chung; Brian T DeVree; Brian K Kobilka; Sheng Li; Tong Liu; Søren G F Rasmussen; Diane Calinski; Pil Seok Chae; Virgil L Woods; Roger K Sunahara
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.
Nature 2011;477(7366):611-5.
2011: Søren G F Rasmussen; Syed T A Shah; georgios skiniotis; Jan Steyaert; Roger K Sunahara; Foon Sun Thian; William I Weis; Yaozhong Zou; Martin Caffrey; Diane Calinski; Pil Seok Chae; Ka Young Chung; Brian T DeVree; Samuel H Gellman; Tong Sun Kobilka; Andrew C Kruse; Joseph A Lyons; Jesper M Mathiesen; Els Pardon; Brian K Kobilka
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Nature 2011;477(7366):549-55.
2011: Gerwin H Westfield; Virgil L Woods; Jan Steyaert; Min Su; Roger K Sunahara; Gisselle Velez-Ruiz; Diane Calinski; Pil Seok Chae; Ka Young Chung; Brian T DeVree; Somnath Dutta; Brian K Kobilka; Sheng Li; Tong Liu; Austin N Oleskie; Els Pardon; Søren G F Rasmussen; georgios skiniotis
Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(38):16086-91.
2011: Gregory T Collins; Kathy A Carey; Diwahar Narasimhan; Joseph Nichols; Aaron A Berlin; Nicholas W Lukacs; Roger K Sunahara; James H Woods; Mei-Chuan Ko
Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(5):1047-59.
2011: Daniel M Rosenbaum; Cheng Zhang; Joseph A Lyons; Ralph Holl; David Aragao; Daniel H Arlow; Søren G F Rasmussen; Hee-Jung Choi; Brian T Devree; Roger K Sunahara; Pil Seok Chae; Samuel H Gellman; Ron O Dror; David E Shaw; William I Weis; Martin Caffrey; Peter Gmeiner; Brian K Kobilka
Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Nature 2011;469(7329):236-40.
2011: Søren G F Rasmussen; Hee-Jung Choi; Juan Jose Fung; Els Pardon; Paola Casarosa; Pil Seok Chae; Brian T Devree; Daniel M Rosenbaum; Foon Sun Thian; Tong Sun Kobilka; Andreas Schnapp; Ingo Konetzki; Roger K Sunahara; Samuel H Gellman; Alexander Pautsch; Jan Steyaert; William I Weis; Brian K Kobilka
Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
Nature 2011;469(7329):175-80.
2011: Gisselle A Vélez-Ruiz; Roger K Sunahara
Reconstitution of G protein-coupled receptors into a model bilayer system: reconstituted high-density lipoprotein particles.
Methods in molecular biology (Clifton, N.J.) 2011;756():167-82.
2010: Diwahar Narasimhan; Mark R Nance; Daquan Gao; Mei-Chuan Ko; Joanne Macdonald; Patricia Tamburi; Dan Yoon; Donald M Landry; James H Woods; Chang-Guo Zhan; John J G Tesmer; Roger K Sunahara
Structural analysis of thermostabilizing mutations of cocaine esterase.
Protein engineering, design & selection : PEDS 2010;23(7):537-47.
2010: Remy L Brim; Mark R Nance; Daniel W Youngstrom; Diwahar Narasimhan; Chang-Guo Zhan; John J G Tesmer; Roger K Sunahara; James H Woods
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse.
Molecular pharmacology 2010;77(4):593-600.
2010: Jun-Beom Park; Young Min Kwon; Tien-Yi Lee; Remy Brim; Mei-Chuan Ko; Roger K Sunahara; James H Woods; Victor C Yang
PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity.
Journal of controlled release : official journal of the Controlled Release Society 2010;142(2):174-9.
2010: Susan K Wood; Diwahar Narasimhan; Ziva D Cooper; Roger K Sunahara; James H Woods
Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats.
Drug and alcohol dependence 2010;106(2-3):219-29.
2009: Juan José Fung; Xavier Deupi; Leonardo Pardo; Xiao Jie Yao; Gisselle A Velez-Ruiz; Brian T Devree; Roger K Sunahara; Brian K Kobilka
Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer.
The EMBO journal 2009;28(21):3315-28.
2009: Gregory Collins; Remy L Brim; Diwahar Narasimhan; Mei-Chuan Ko; Roger K Sunahara; Chang-Guo Zhan; James H Woods
Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats.
The Journal of pharmacology and experimental therapeutics 2009;331(2):445-55.
2009: Adam J Kuszak; Sethuramasundaram Pitchiaya; Jessica P Anand; Henry I Mosberg; Nils G Walter; Roger K Sunahara
Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.
The Journal of biological chemistry 2009;284(39):26732-41.
2009: Emily Jutkiewicz; Michelle G Baladi; Ziva D Cooper; Diwahar Narasimhan; Roger K Sunahara; James H Woods
A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality.
Annals of emergency medicine 2009;54(3):409-20.
2009: Xiao Jie Yao; Gisselle Vélez Ruiz; Matthew R Whorton; Søren G F Rasmussen; Brian T DeVree; Xavier Deupi; Roger K Sunahara; Brian Kobilka
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9501-6.
2009: Mei-Chuan Ko; Diwahar Narasimhan; Aaron A Berlin; Nicholas W Lukacs; Roger K Sunahara; James H Woods
Effects of cocaine esterase following its repeated administration with cocaine in mice.
Drug and alcohol dependence 2009;101(3):202-9.
2009: Gregory Collins; Andrew Truccone; Faiza Haji-Abdi; Amy Hauck Newman; Peter Grundt; Kenner C Rice; Stephen M Husbands; Benjamin M Greedy; Cecile Enguehard-Gueiffier; Alain Gueiffier; Jianyong Chen; Shaomeng Wang; Jonathan L Katz; David K Grandy; Roger K Sunahara; James H Woods
Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice.
The Journal of pharmacology and experimental therapeutics 2009;329(1):210-7.
2009: Daquan Gao; Diwahar L Narasimhan; Joanne Macdonald; Remy Brim; Mei-Chuan Ko; Donald W Landry; James H Woods; Roger K Sunahara; Chang-Guo Zhan
Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.
Molecular pharmacology 2009;75(2):318-23.
2008: Matthew R Whorton; Beata Jastrzebska; Paul S-H Park; Dimitrios Fotiadis; Andreas Engel; Krzysztof Palczewski; Roger K Sunahara
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer.
The Journal of biological chemistry 2008;283(7):4387-94.
2007: Jennifer M Cunliffe; Roger K Sunahara; Robert T Kennedy
Detection of g protein coupled receptor mediated adenylyl cyclase activity by capillary electrophoresis using fluorescently labeled ATP.
Analytical chemistry 2007;79(19):7534-9.
2007: Jennifer M Cunliffe; Matthew R Whorton; Roger K Sunahara; Robert T Kennedy
A CE assay for the detection of agonist-stimulated adenylyl cyclase activity.
Electrophoresis 2007;28(12):1913-20.
2007: Kannan Vadakkadathmeethal; Jennifer M Cunliffe; Jennifer Swift; Robert T Kennedy ; Richard Neubig; Roger K Sunahara
Fluorescence-based adenylyl cyclase assay adaptable to high throughput screening.
Combinatorial chemistry & high throughput screening 2007;10(4):289-98.
2007: Matthew R Whorton; Michael P Bokoch; Søren G F Rasmussen; Bo Huang; Richard N Zare; Brian Kobilka; Roger K Sunahara
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7682-7.
2007: Johannes Bodenstein; Roger K Sunahara; Richard Neubig
N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells.
Molecular pharmacology 2007;71(4):1040-50.
2007: Mark D Benson; Qiu-Ju Li; Katherine Kieckhafer; David Dudek; Matthew R Whorton; Roger K Sunahara; Jorge A Iniguez-Lluhi; Jeffrey R Martens
SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(6):1805-10.
2007: Nils Walter; Jens-Christian Meiners; Edgar Meyhofer; Richard Neubig; Roger K Sunahara; Noel C Perkins; Duncan G Steel; Joel A Swanson
Under the microscope: single molecule symposium at the University of Michigan, 2006.
Biopolymers 2007;85(2):106-14.
2007: Mei-Chuan Ko; Luvina D Bowen; Diwahar Narasimhan; Aaron A Berlin; Nicholas W Lukacs; Roger K Sunahara; Ziva D Cooper; James H Woods
Cocaine esterase: interactions with cocaine and immune responses in mice.
The Journal of pharmacology and experimental therapeutics 2007;320(2):926-33.
2007: David Roman; Jeffery N Talbot; Rebecca A Roof; Roger K Sunahara; John R Traynor; Richard Neubig
Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay.
Molecular pharmacology 2007;71(1):169-75.
2006: Ziva D Cooper; Diwahar Narasimhan; Roger K Sunahara; Pawel Mierzejewski; Emily Jutkiewicz; Nicholas A Larsen; Ian A Wilson; Donald W Landry; James H Woods
Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.
Molecular pharmacology 2006;70(6):1885-91.
2006: Patrick Giguère; Moulay Driss Rochdi; Geneviève Laroche; Emilie Dupré; Matthew R Whorton; Roger K Sunahara; Audrey Claing; Gilles Dupuis; Jean-Luc Parent
ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6.
Cellular signalling 2006;18(11):1988-94.
2006: Rebecca A Roof; Yafei Jin; David Roman; Roger K Sunahara; Masaru Ishii; Henry I Mosberg; Richard Neubig
Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins.
Chemical biology & drug design 2006;67(4):266-74.
2006: Jennifer M Cunliffe; Roger K Sunahara; Robert T Kennedy
Detection of adenylyl cyclase activity using a fluorescent ATP substrate and capillary electrophoresis.
Analytical chemistry 2006;78(6):1731-8.
2005: Yoshihiro Morishima; Hwei-Ming Peng; Hsia-lien Lin; Paul Hollenberg; Roger K Sunahara; Yoichi Osawa; William B Pratt
Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation.
Biochemistry 2005;44(49):16333-40.
2005: Dragomir I Draganov; John F Teiber; Audrey Speelman; Yoichi Osawa; Roger K Sunahara; Bert N La Du
Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities.
Journal of lipid research 2005;46(6):1239-47.
2005: Kannan Vadakkadathmeethal; Aimee Felczak; Isabelle Davignon; Julie Collins; Roger K Sunahara
Cloning and characterization of the G protein betagamma subunits from Trichoplusia ni (High Five cells).
Insect biochemistry and molecular biology 2005;35(4):333-45.
2005: Fu-Jung Chang; Scott Lemme; Qian Sun; Roger K Sunahara; Annie Beuve
Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase.
The Journal of biological chemistry 2005;280(12):11513-9.
2005: Emily E Jameson; Rebecca A Roof; Matthew R Whorton; Henry I Mosberg; Roger K Sunahara; Richard Neubig; Robert T Kennedy
Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues.
The Journal of biological chemistry 2005;280(9):7712-9.
2004: Rebecca J Whelan; Roger K Sunahara; Richard Neubig; Robert T Kennedy
Affinity assays using fluorescence anisotropy with capillary electrophoresis separation.
Analytical chemistry 2004;76(24):7380-6.
2004: Claudette Klein; Tomasz Heyduk; Roger K Sunahara
Zinc inhibition of adenylyl cyclase correlates with conformational changes in the enzyme.
Cellular signalling 2004;16(10):1177-85.
2004: Andrejs M Krumins; Sheryll A Barker; Chunfa Huang; Roger K Sunahara; Kan Yu; Thomas Wilkie; Stephen J Gold; Susanne M Mumby
Differentially regulated expression of endogenous RGS4 and RGS7.
The Journal of biological chemistry 2004;279(4):2593-9.
2003: Yoshihiro Morishima; Kimon C Kanelakis; Patrick J M Murphy; Ezra R Lowe; Gary J Jenkins; Yoichi Osawa; Roger K Sunahara; William B Pratt
The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex.
The Journal of biological chemistry 2003;278(49):48754-63.
2003: Emily E Jameson; Jennifer M Cunliffe; Richard Neubig; Roger K Sunahara; Robert T Kennedy
Detection of G proteins by affinity probe capillary electrophoresis using a fluorescently labeled GTP analogue.
Analytical chemistry 2003;75(16):4297-304.
2002: Roger K Sunahara; Ron Taussig
Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.
Molecular interventions 2002;2(3):168-84.
2002: Claudette Klein; Roger K Sunahara; Tracie Y Hudson; Tomasz Heyduk; Allyn C Howlett
Zinc inhibition of cAMP signaling.
The Journal of biological chemistry 2002;277(14):11859-65.
2002: John J G Tesmer; Roger K Sunahara; David A Fancy; Alfred G Gilman; Stephen R Sprang
Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha.
Methods in enzymology 2002;345():198-206.
2002: Mark E Hatley; Alfred G Gilman; Roger K Sunahara
Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases.
Methods in enzymology 2002;345():127-40.
2001: L Wang; Roger K Sunahara; Andrejs M Krumins; G Perkins; M L Crochiere; M Mackey; Sean Bell; M H Ellisman; Susan S Taylor
Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3220-5.
2000: Mark E Hatley; B K Benton; J Xu; J P Manfredi; Alfred G Gilman; Roger K Sunahara
Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase.
The Journal of biological chemistry 2000;275(49):38626-32.
2000: John J G Tesmer; Carmen W Dessauer; Roger K Sunahara; L D Murray; R A Johnson; Alfred G Gilman; Stephen R Sprang
Molecular basis for P-site inhibition of adenylyl cyclase.
Biochemistry 2000;39(47):14464-71.
2000: Brian Ciliax; Norman R Nash; Craig J Heilman; Roger K Sunahara; A Hartney; M Tiberi; David B Rye; Marc G Caron; Hyman B Niznik; Allan Levey
Dopamine D(5) receptor immunolocalization in rat and monkey brain.
Synapse (New York, N.Y.) 2000;37(2):125-45.
1999: John J G Tesmer; Roger K Sunahara; R A Johnson; G Gosselin; Alfred G Gilman; Stephen R Sprang
Two-metal-Ion catalysis in adenylyl cyclase.
Science (New York, N.Y.) 1999;285(5428):756-60.
1998: Roger K Sunahara; Annie Beuve; John J G Tesmer; Stephen R Sprang; David L Garbers; Alfred G Gilman
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.
The Journal of biological chemistry 1998;273(26):16332-8.
1997: John J G Tesmer; Roger K Sunahara; Alfred G Gilman; Stephen R Sprang
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.
Science (New York, N.Y.) 1997;278(5345):1907-16.
1997: Roger K Sunahara; John J G Tesmer; Alfred G Gilman; Stephen R Sprang
Crystal structure of the adenylyl cyclase activator Gsalpha.
Science (New York, N.Y.) 1997;278(5345):1943-7.
1997: Per Svenningsson; Catherine Le Moine; Björn Kull; Roger K Sunahara; Bertrand Bloch; Bertil B. Fredholm
Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas.
Neuroscience 1997;80(4):1171-85.
1997: Roger K Sunahara; Carmen W Dessauer; R E Whisnant; C Kleuss; Alfred G Gilman
Interaction of Gsalpha with the cytosolic domains of mammalian adenylyl cyclase.
The Journal of biological chemistry 1997;272(35):22265-71.
1997: William Durante; Nicolaos Christodoulides; K Cheng; Kelly J Peyton; Roger K Sunahara; Andrew I Schafer
cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle.
The American journal of physiology 1997;273(1 Pt 2):H317-23.
1996: Roger K Sunahara; Carmen W Dessauer; Alfred G Gilman
Complexity and diversity of mammalian adenylyl cyclases.
Annual review of pharmacology and toxicology 1996;36():461-80.
1995: William Durante; K Cheng; Roger K Sunahara; Andrew I Schafer
Ethanol potentiates interleukin-1 beta-stimulated inducible nitric oxide synthase expression in cultured vascular smooth muscle cells.
The Biochemical journal 1995;308 ( Pt 1)():231-6.
1994: Philip Seeman; Roger K Sunahara; Hyman B Niznik
Receptor-receptor link in membranes revealed by ligand competition: example for dopamine D1 and D2 receptors.
Synapse (New York, N.Y.) 1994;17(1):62-4.
1993: Roger K Sunahara; Philip Seeman; Hubert H M Van Tol; Hyman B Niznik
Dopamine receptors and antipsychotic drug response.
The British journal of psychiatry. Supplement 1993;(22):31-8.
1993: Allan Levey; Steven M Hersch; David B Rye; Roger K Sunahara; Hyman B Niznik; C A Kitt; Donald L Price; R Maggio; Mark R Brann; Brian Ciliax
Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8861-5.
1993: L L Demchyshyn; Coimbatore B Srikant; Roger K Sunahara; Geraldine Kent; Philip Seeman; Hubert H M Van Tol; Rosemarie Panetta; Yogesh C Patel; Hyman B Niznik
Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20.
Molecular pharmacology 1993;43(6):894-901.
1993: Joel Gelernter; James L Kennedy; David K Grandy; Q Y Zhou; Olivier Civelli; D L Pauls; Andrew J Pakstis; Roger Kurlan; Roger K Sunahara; Hyman B Niznik
Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor.
The American journal of psychiatry 1993;150(3):449-53.
1993: K Ohara; C Ulpian; Philip Seeman; Roger K Sunahara; Hubert H M Van Tol; Hyman B Niznik
Schizophrenia: dopamine D1 receptor sequence is normal, but has DNA polymorphisms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1993;8(2):131-5.
1993: Kim S Sugamori; Roger K Sunahara; Hong-Chang Guan; A G Bulloch; C P Tensen; Philip Seeman; Hyman B Niznik; Hubert H M Van Tol
Serotonin receptor cDNA cloned from Lymnaea stagnalis.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):11-5.
1992: Philip Seeman; Hong-Chang Guan; Olivier Civelli; Hubert H M Van Tol; Roger K Sunahara; Hyman B Niznik
The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography.
European journal of pharmacology 1992;227(2):139-46.
1992: L Demchyshyn; Roger K Sunahara; K Miller; Milt Teitler; B J Hoffman; James L Kennedy; Philip Seeman; Hubert H M Van Tol; Hyman B Niznik
A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5522-6.
1992: Guadalupe Mengod; M T Villaró; G B Landwehrmeyer; M I Martinez-Mir; Hyman B Niznik; Roger K Sunahara; Philip Seeman; Brian F O'Dowd; Alphonse Probst; J M Palacios
Visualization of dopamine D1, D2 and D3 receptor mRNAs in human and rat brain.
Neurochemistry international 1992;20 Suppl():33S-43S.
1991: T Nguyen; Roger K Sunahara; A Marchese; Hubert H M Van Tol; Philip Seeman; Brian F O'Dowd
Transcription of a human dopamine D5 pseudogene.
Biochemical and biophysical research communications 1991;181(1):16-21.
1991: Rachel F Tyndale; Roger K Sunahara; T Inaba; Werner Kalow; F J Gonzalez; Hyman B Niznik
Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6.
Molecular pharmacology 1991;40(1):63-8.
1991: Guadalupe Mengod; M Teresa Vilaró; Hyman B Niznik; Roger K Sunahara; Philip Seeman; Brian F O'Dowd; J M Palacios
Visualization of a dopamine D1 receptor mRNA in human and rat brain.
Brain research. Molecular brain research 1991;10(2):185-91.
1991: Hubert H M Van Tol; James R Bunzow; Hong-Chang Guan; Roger K Sunahara; Philip Seeman; Hyman B Niznik; Olivier Civelli
Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine.
Nature 1991;350(6319):610-4.
1991: Roger K Sunahara; Hong-Chang Guan; Brian F O'Dowd; Philip Seeman; Lisanne G Laurier; Gordon Y K Ng; Susan R George; J Torchia; Hubert H M Van Tol; Hyman B Niznik
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
Nature 1991;350(6319):614-9.
1991: D M Weiner; Allan Levey; Roger K Sunahara; Hyman B Niznik; Brian F O'Dowd; Philip Seeman; Mark R Brann
D1 and D2 dopamine receptor mRNA in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1859-63.
1991: B S Tuana; Roger K Sunahara; B J Murphy; G N Pierce
Two major antigens of heart sarcolemma are Ca2(+)-binding glycoproteins that copurify with the dihydropyridine receptor.
Biochimica et biophysica acta 1991;1091(2):236-41.
1990: Roger K Sunahara; Hyman B Niznik; D M Weiner; T M Stormann; Mark R Brann; James L Kennedy; Joel Gelernter; Richard Rozmahel; Y L Yang; Y Israel
Human dopamine D1 receptor encoded by an intronless gene on chromosome 5.
Nature 1990;347(6288):80-3.
1990: Roger K Sunahara; B J Murphy; B S Tuana
A sensitive and rapid method for identification and characterization of low abundance receptors.
Analytical biochemistry 1990;185(1):143-6.
1990: B J Murphy; C A Rogers; Roger K Sunahara; Simon Lemaire; B S Tuana
Identification, characterization, and photoaffinity labeling of the dihydropyridine receptor associated with the L-type calcium channel from bovine adrenal medulla.
Molecular pharmacology 1990;37(2):173-81.