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Rosanna Supino

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M C Anania; Maria Grazia Borrello; Loredana Cleris; Enrica Favini; Franca Formelli; Claudia Miranda; Sonia Pagliardini; Marco A Pierotti; Enrico Radaelli; M Sensi; Rosanna Supino; M G Vizioli; Angela Greco
TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.
Zareen Amtul; Markus Uhrig; Rosanna Supino; Konrad Beyreuther
Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios.
Valentina Zuco; Rosanna Supino; Enrica Favini; Monica Tortoreto; Raffaella Cincinelli; Anna Cleta Croce; Federica Bucci; Claudio Pisano; Franco Zunino
Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma.

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All Publications

2011: M C Anania; Maria Grazia Borrello; Loredana Cleris; Enrica Favini; Franca Formelli; Claudia Miranda; Sonia Pagliardini; Marco A Pierotti; Enrico Radaelli; M Sensi; Rosanna Supino; M G Vizioli; Angela Greco
TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.
Oncogene 2011;30(27):3011-23.
2010: Zareen Amtul; Markus Uhrig; Rosanna Supino; Konrad Beyreuther
Phospholipids and a phospholipid-rich diet alter the in vitro amyloid-beta peptide levels and amyloid-beta 42/40 ratios.
Neuroscience letters 2010;481(2):73-7.
2010: Valentina Zuco; Rosanna Supino; Enrica Favini; Monica Tortoreto; Raffaella Cincinelli; Anna Cleta Croce; Federica Bucci; Claudio Pisano; Franco Zunino
Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma.
Biochemical pharmacology 2010;79(4):535-41.
2010: Marco Folini; Paolo Gandellini; Nicole Longoni; Valentina Profumo; Maurizio Callari; Marzia Pennati; Maurizio Colecchia; Rosanna Supino; Silvia Veneroni; Roberto Salvioni; Riccardo Valdagni; Maria Grazia Daidone; Nadia Zaffaroni
miR-21: an oncomir on strike in prostate cancer.
Molecular cancer 2010;9():12.
2010: Michelandrea De Cesare; Lucia Sfondrini; Manuela Campiglio; Michele Sommariva; Francesca Bianchi; Paola Perego; Nico van Rooijen; Rosanna Supino; Cristiano Rumio; Franco Zunino; Graziella Pratesi; Elda Tagliabue; Andrea Balsari
Ascites regression and survival increase in mice bearing advanced-stage human ovarian carcinomas and repeatedly treated intraperitoneally with CpG-ODN.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(1):8-15.
2009: Rosanna Supino; Anna Scovassi; Anna Cleta Croce; Laura Dal Bo; Enrica Favini; Alessandro Corbelli; Carlo Farina; Paola Misiano; Franco Zunino
Biological effects of a new vacuolar-H,-ATPase inhibitor in colon carcinoma cell lines.
Annals of the New York Academy of Sciences 2009;1171():606-16.
2009: Chiara Giommarelli; Alessandro Corti; Rosanna Supino; Enrica Favini; Aldo Paolicchi; Alfonso Pompella; Franco Zunino
Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid.
Free radical biology & medicine 2009;46(11):1516-26.
2009: Paolo Gandellini; Marco Folini; Nicole Longoni; Marzia Pennati; Mara Binda; Maurizio Colecchia; Roberto Salvioni; Rosanna Supino; Roberta Moretti; Patrizia Limonta; Riccardo Valdagni; Maria Grazia Daidone; Nadia Zaffaroni
miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.
Cancer research 2009;69(6):2287-95.
2008: Chiara Giommarelli; Alessandro Corti; Rosanna Supino; Enrica Favini; Aldo Paolicchi; Alfonso Pompella; Franco Zunino
Cellular response to oxidative stress and ascorbic acid in melanoma cells overexpressing gamma-glutamyltransferase.
European journal of cancer (Oxford, England : 1990) 2008;44(5):750-9.
2008: Rosanna Supino; Giovanna Petrangolini; Graziella Pratesi; Monica Tortoreto; Enrica Favini; Laura Dal Bo; Patrizia Casalini; Enrico Radaelli; Anna Cleta Croce; Giovanni Bottiroli; Paola Misiano; Carlo Farina; Franco Zunino
Antimetastatic effect of a small-molecule vacuolar H+-ATPase inhibitor in in vitro and in vivo preclinical studies.
The Journal of pharmacology and experimental therapeutics 2008;324(1):15-22.
2007: Claudio Pisano; Loredana Vesci; R Foderà; Fabiana Fosca Ferrara; C Rossi; Michelandrea De Cesare; Valentina Zuco; Graziella Pratesi; Rosanna Supino; Franco Zunino
Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(9):1500-5.
2007: Rosanna Supino; Enrica Favini; Giuditta Cuccuru; Franco Zunino; Anna Scovassi
Effect of paclitaxel on intracellular localization of c-Myc and P-c-Myc in prostate carcinoma cell lines.
Annals of the New York Academy of Sciences 2007;1095():175-81.
2006: Giuliana Cassinelli; Cinzia Lanzi; Giovanna Petrangolini; Monica Tortoreto; Graziella Pratesi; Giuditta Cuccuru; Diletta Laccabue; Rosanna Supino; Sara Belluco; Enrica Favini; Anna Poletti; Franco Zunino
Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1.
Molecular cancer therapeutics 2006;5(9):2388-97.
2006: Giovanna Petrangolini; Rosanna Supino; Graziella Pratesi; Laura Dal Bo; Monica Tortoreto; Anna Cleta Croce; Paola Misiano; Pietro Belfiore; Carlo Farina; Franco Zunino
Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.
The Journal of pharmacology and experimental therapeutics 2006;318(3):939-46.
2005: Valentina Zuco; Chiara Zanchi; Cinzia Lanzi; Giovanni L Beretta; Rosanna Supino; Claudio Pisano; Marcella Barbarino; Romina Zanier; Federica Bucci; Concetta Aulicino; Paolo Carminati; Franco Zunino
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Neoplasia (New York, N.Y.) 2005;7(7):667-77.
2005: Chiara Zanchi; Valentina Zuco; Cinzia Lanzi; Rosanna Supino; Franco Zunino
Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839.
Cancer research 2005;65(6):2364-72.
2005: Paola Ulivi; Wainer Zoli; Francesco Fabbri; Giovanni Brigliadori; Luca Ricotti; Anna Tesei; Marco Rosetti; Michelandrea De Cesare; Giovanni Luca Beretta; Elisabetta Corna; Rosanna Supino; Franco Zunino
Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.
Neoplasia (New York, N.Y.) 2005;7(2):152-61.
2004: Elena Zarini; Rosanna Supino; Graziella Pratesi; Diletta Laccabue; Monica Tortoreto; Eugenio Scanziani; Gabriele Ghisleni; Saverio Paltrinieri; Gianfranco Tunesi; Maurizio Nava
Biocompatibility and tissue interactions of a new filler material for medical use.
Plastic and reconstructive surgery 2004;114(4):934-42.
2004: Giuliana Cassinelli; Rosanna Supino; Valentina Zuco; Cinzia Lanzi; Anna Scovassi; Sean C Semple; Franco Zunino
Role of c-myc protein in hormone refractory prostate carcinoma: cellular response to paclitaxel.
Biochemical pharmacology 2004;68(5):923-31.
2004: Zareen Amtul; Maimoona Rasheed; M Iqbal Choudhary; Rosanna Supino; Khalid M Khan; Supino Rosanna
Kinetics of novel competitive inhibitors of urease enzymes by a focused library of oxadiazoles/thiadiazoles and triazoles.
Biochemical and biophysical research communications 2004;319(3):1053-63.
2004: Giovanna Petrangolini; Giuliana Cassinelli; Graziella Pratesi; Monica Tortoreto; Enrica Favini; Rosanna Supino; Cinzia Lanzi; Sara Belluco; Franco Zunino
Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft.
British journal of cancer 2004;90(7):1464-8.
2004: Anna Cleta Croce; Giovanni Bottiroli; Rosanna Supino; Enrica Favini; Valentina Zuco; Franco Zunino
Subcellular localization of the camptothecin analogues, topotecan and gimatecan.
Biochemical pharmacology 2004;67(6):1035-45.
2004: Valentina Zuco; Chiara Zanchi; Giuliana Cassinelli; Cinzia Lanzi; Rosanna Supino; Claudio Pisano; Romina Zanier; Vincenzo Giordano; Enrico Garattini; Franco Zunino
Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid.
Cell death and differentiation 2004;11(3):280-9.
2003: Giovanna Petrangolini; Graziella Pratesi; Michelandrea De Cesare; Rosanna Supino; Claudio Pisano; Marcella Marcellini; Vincenzo Giordano; Diletta Laccabue; Cinzia Lanzi; Franco Zunino
Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts.
Molecular cancer research : MCR 2003;1(12):863-70.
2003: Cinzia Lanzi; Giuliana Cassinelli; Giuditta Cuccuru; Nadia Zaffaroni; Rosanna Supino; Sara Vignati; Chiara Zanchi; M Yamamoto; Franco Zunino
Inactivation of Ret/Ptc1 oncoprotein and inhibition of papillary thyroid carcinoma cell proliferation by indolinone RPI-1.
Cellular and molecular life sciences : CMLS 2003;60(7):1449-59.
2003: Chiara Gorrini; Maddalena Donzelli; Alicia Torriglia; Rosanna Supino; Olivier Brison; Rosa Bernardi; Claudia Negri; Marco Denegri; Marie-France Counis; Guglielmina Nadia Ranzani; Anna Scovassi
Effect of apoptogenic stimuli on colon carcinoma cell lines with a different c-myc expression level.
International journal of molecular medicine 2003;11(6):737-42.
2003: Valentina Zuco; Rosanna Supino; Michelandrea De Cesare; Nives Carenini; Paola Perego; Laura Gatti; Graziella Pratesi; Claudio Pisano; Roberta Martinelli; Federica Bucci; Romina Zanier; Paolo Carminati; Franco Zunino
Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
Biochemical pharmacology 2003;65(8):1281-94.
2003: Graziella Pratesi; Diletta Laccabue; Cinzia Lanzi; Giuliana Cassinelli; Rosanna Supino; Massimo Zucchetti; Roberta Frapolli; Maurizio D'Incalci; Ezio Bombardelli; Paolo Morazzoni; Antonella Riva; Franco Zunino
IDN 5390: an oral taxane candidate for protracted treatment schedules.
British journal of cancer 2003;88(6):965-72.
2003: Raffaella Cincinelli; Sabrina Dallavalle; Lucio Merlini; Sergio Penco; Claudio Pisano; Paolo Carminati; Giuseppe Giannini; Loredana Vesci; carlo gaetano; Barbara Illy; Valentina Zuco; Rosanna Supino; Franco Zunino
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
Journal of medicinal chemistry 2003;46(6):909-12.
2002: Laura Gatti; Rosanna Supino; Paola Perego; R Pavesi; C Caserini; Nives Carenini; Sabina C Righetti; Valentina Zuco; Franco Zunino
Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.
Cell death and differentiation 2002;9(12):1352-9.
2002: Nadia Zaffaroni; Marzia Pennati; Gennaro Colella; Paola Perego; Rosanna Supino; Laura Gatti; Silvana Pilotti; Franco Zunino; Maria Grazia Daidone
Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer.
Cellular and molecular life sciences : CMLS 2002;59(8):1406-12.
2002: Giuliana Cassinelli; Cinzia Lanzi; Rosanna Supino; Graziella Pratesi; Valentina Zuco; Diletta Laccabue; Giuditta Cuccuru; Ezio Bombardelli; Franco Zunino
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2647-54.
2002: Aldo Paolicchi; Evelina Lorenzini; Paola Perego; Rosanna Supino; Franco Zunino; Mario Comporti; Alfonso Pompella
Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: implications for cell response to platinum-based drugs.
International journal of cancer. Journal international du cancer 2002;97(6):740-5.
2002: Valentina Zuco; Rosanna Supino; Sabina C Righetti; Loredana Cleris; Edoardo Marchesi; Carlo Gambacorti-Passerini; Franca Formelli
Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells.
Cancer letters 2002;175(1):17-25.
2002: Anna Cleta Croce; Rosanna Supino; Karen S Lanza; Davide Locatelli; Piero Baglioni; Giovanni Bottiroli
Photosensitizer accumulation in spontaneous multidrug resistant cells: a comparative study with Rhodamine 123, Rose Bengal acetate and Photofrine.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2002;1(1):71-8.
2001: Federica Riva; Valentina Zuco; A A Vink; Rosanna Supino; Ennio Prosperi
UV-induced DNA incision and proliferating cell nuclear antigen recruitment to repair sites occur independently of p53-replication protein A interaction in p53 wild type and mutant ovarian carcinoma cells.
Carcinogenesis 2001;22(12):1971-8.
2001: Rosanna Supino; Paola Perego; Laura Gatti; C Caserini; Carlo Leonetti; M Colantuono; Valentina Zuco; Nives Carenini; Gabriella Zupi; Franco Zunino
A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line.
European journal of cancer (Oxford, England : 1990) 2001;37(17):2247-56.
2001: Cinzia Lanzi; Giuliana Cassinelli; Giuditta Cuccuru; Rosanna Supino; Valentina Zuco; C Ferlini; Ferlini Cristiano; Franco Zunino
Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells.
The Prostate 2001;48(4):254-64.
2001: Rosanna Supino; Maria Grazia Bottone; Carlo Pellicciari; C Caserini; Giovanni Bottiroli; M Belleri; Arsenio Veicsteinas
Sinusoidal 50 Hz magnetic fields do not affect structural morphology and proliferation of human cells in vitro.
Histology and histopathology 2001;16(3):719-26.
2001: Giuliana Cassinelli; Rosanna Supino; Paola Perego; D Polizzi; Cinzia Lanzi; Graziella Pratesi; Franco Zunino
A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes.
International journal of cancer. Journal international du cancer 2001;92(5):738-47.
2001: Rosanna Supino; D Polizzi; R Pavesi; Graziella Pratesi; F Guano; Giovanni Capranico; Manlio Palumbo; Claudia Sissi; S Richter; Gino Beggiolin; Ernesto Menta; Gabriella Pezzoni; S Spinelli; D Torriani; Nives Carenini; Laura Dal Bo; F Facchinetti; Monica Tortoreto; Franco Zunino
A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts.
Oncology 2001;61(3):234-42.
2001: Eugenio Monti; Rosanna Supino; M Colleoni; B Costa; Raffaella Ravizza; Marzia B Gariboldi
Nitroxide TEMPOL impairs mitochondrial function and induces apoptosis in HL60 cells.
Journal of cellular biochemistry 2001;82(2):271-6.
2001: Paola Perego; Elisabetta Corna; Michelandrea De Cesare; Laura Gatti; D Polizzi; Graziella Pratesi; Rosanna Supino; Franco Zunino
Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.
Current medicinal chemistry 2001;8(1):31-7.
2000: Marzia B Gariboldi; V Rimoldi; Rosanna Supino; Enrica Favini; Eugenio Monti
The nitroxide tempol induces oxidative stress, p21(WAF1/CIP1), and cell death in HL60 cells.
Free radical biology & medicine 2000;29(7):633-41.
2000: Emilia Maellaro; Silvia Dominici; Barbara Del Bello; Marta A Valentini; Lisa Pieri; Paola Perego; Rosanna Supino; Franco Zunino; Evelina Lorenzini; Aldo Paolicchi; Mario Comporti; Alfonso Pompella
Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status.
Journal of cell science 2000;113 ( Pt 15)():2671-8.
2000: Carla Manzotti; Graziella Pratesi; Ernesto Menta; R Di Domenico; Ennio Cavalletti; H H Fiebig; Lloyd R Kelland; Nicholas Farrell; D Polizzi; Rosanna Supino; Gabriella Pezzoni; Franco Zunino
BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2626-34.
2000: Philipp le Coutre; E Tassi; M Varella-Garcia; R Barni; Luca Mologni; G Cabrita; Edoardo Marchesi; Rosanna Supino; Carlo Gambacorti-Passerini
Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification.
Blood 2000;95(5):1758-66.
2000: Giuseppe Zagotto; Rosanna Supino; Enrica Favini; Stefano Moro; Manlio Palumbo
New 1,4-anthracene-9,10-dione derivatives as potential anticancer agents.
Farmaco (Società chimica italiana : 1989) 2000;55(1):1-5.
1999: Paola Perego; Laura Gatti; C Caserini; Rosanna Supino; Donato Colangelo; Roberto Leone; S Spinelli; Nicholas Farrell; Franco Zunino
The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells.
Journal of inorganic biochemistry 1999;77(1-2):59-64.
1999: B Stefańska; Maria Dzieduszycka; Maria M Bontemps-Gracz; Edward Borowski; Sante Martelli; Rosanna Supino; G Pratesi; Michelandrea De Cesare; F Zunino; H Kuśnierczyk; Czeslaw Radzikowski
8,11-dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with activity in multidrug-resistant cell lines: synthesis and antitumor evaluation.
Journal of medicinal chemistry 1999;42(18):3494-501.
1999: Graziella Pratesi; Paola Perego; D Polizzi; Sabina C Righetti; Rosanna Supino; C Caserini; Carla Manzotti; FC Giuliani; Gabriella Pezzoni; S Tognella; S Spinelli; Nicholas Farrell; Franco Zunino
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts.
British journal of cancer 1999;80(12):1912-9.
1999: FM Arcamone; Fabio Animati; Mario Bigioni; Giovanni Capranico; C Caserini; A Cipollone; Michelandrea De Cesare; A Ettorre; F Guano; Stefano Manzini; ES Monteagudo; Graziella Pratesi; Carmela Salvatore; Rosanna Supino; Franco Zunino
Configurational requirements of the sugar moiety for the pharmacological activity of anthracycline disaccharides.
Biochemical pharmacology 1999;57(10):1133-9.
1999: D Polizzi; Graziella Pratesi; Monica Tortoreto; Rosanna Supino; Antonella Riva; Ezio Bombardelli; Franco Zunino
A novel taxane with improved tolerability and therapeutic activity in a panel of human tumor xenografts.
Cancer research 1999;59(5):1036-40.
1999: Paola Perego; C Caserini; Laura Gatti; Nives Carenini; S Romanelli; Rosanna Supino; Donato Colangelo; Ilario Viano; Roberto Leone; S Spinelli; Gabriella Pezzoni; Carla Manzotti; Nicholas Farrell; Franco Zunino
A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system.
Molecular pharmacology 1999;55(3):528-34.
1998: Graziella Pratesi; Michelandrea De Cesare; C Caserini; Paola Perego; Laura Dal Bo; D Polizzi; Rosanna Supino; Mario Bigioni; Stefano Manzini; Elisabetta Iafrate; Carmela Salvatore; A Casazza; FM Arcamone; Franco Zunino
Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2833-9.
1998: Cinzia Lanzi; Paola Perego; Rosanna Supino; S Romanelli; T Pensa; Nives Carenini; Ilario Viano; Donato Colangelo; Roberto Leone; Pietro Apostoli; Giuliana Cassinelli; RA Gambetta; Franco Zunino
Decreased drug accumulation and increased tolerance to DNA damage in tumor cells with a low level of cisplatin resistance.
Biochemical pharmacology 1998;55(8):1247-54.
1998: Marzia B Gariboldi; Simona Lucchi; C Caserini; Rosanna Supino; Cesare Oliva; Eugenio Monti
Antiproliferative effect of the piperidine nitroxide TEMPOL on neoplastic and nonneoplastic mammalian cell lines.
Free radical biology & medicine 1998;24(6):913-23.
1997: Franco Zunino; Paola Perego; S Pilotti; Graziella Pratesi; Rosanna Supino; FM Arcamone
Role of apoptotic response in cellular resistance to cytotoxic agents.
Pharmacology & therapeutics 1997;76(1-3):177-85.
1997: FM Arcamone; Fabio Animati; Giovanni Capranico; Paolo Lombardi; Graziella Pratesi; Stefano Manzini; Rosanna Supino; Franco Zunino
New developments in antitumor anthracyclines.
Pharmacology & therapeutics 1997;76(1-3):117-24.
1997: Mario Bigioni; Carmela Salvatore; Carla Palma; Stefano Manzini; Fabio Animati; Paolo Lombardi; Graziella Pratesi; Rosanna Supino; Franco Zunino
Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin.
Anti-cancer drugs 1997;8(9):845-52.
1997: FM Arcamone; Fabio Animati; M Berettoni; Mario Bigioni; Giovanni Capranico; A M Casazza; C Caserini; A Cipollone; Michelandrea De Cesare; M Franciotti; Paolo Lombardi; Andrea Madami; Stefano Manzini; ES Monteagudo; D Polizzi; Graziella Pratesi; Sabina C Righetti; Carmela Salvatore; Rosanna Supino; Franco Zunino
Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.
Journal of the National Cancer Institute 1997;89(16):1217-23.
1997: C Caserini; Graziella Pratesi; Monica Tortoreto; B Bedogné; Nives Carenini; Rosanna Supino; Paola Perego; Sabina C Righetti; Franco Zunino
Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(6):955-61.
1997: Paola Perego; Sabina C Righetti; Rosanna Supino; Domenico Delia; C Caserini; Nives Carenini; B Bedogné; E Broome; S Krajewski; J C Reed; Franco Zunino
Role of apoptosis and apoptosis-related proteins in the cisplatin-resistant phenotype of human tumor cell lines.
Apoptosis : an international journal on programmed cell death 1997;2(6):540-8.
1996: Fabio Animati; FM Arcamone; Mario Bigioni; Giovanni Capranico; C Caserini; Michelandrea De Cesare; Paolo Lombardi; Graziella Pratesi; Carmela Salvatore; Rosanna Supino; Franco Zunino
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation.
Molecular pharmacology 1996;50(3):603-9.
1996: Rosanna Supino; C Caserini; Linda Orlandi; Nadia Zaffaroni; R Silvestrini; Maurizio Vaglini; Franco Zunino
Modulation of melphalan cytotoxic activity in human melanoma cell lines.
Anti-cancer drugs 1996;7(5):604-12.
1996: Renato Marchesini; A Colombo; C Caserini; Paola Perego; Rosanna Supino; Giovanni Capranico; M Tronconi; Franco Zunino
Interaction of ionizing radiation with topotecan in two human tumor cell lines.
International journal of cancer. Journal international du cancer 1996;66(3):342-6.
1996: Rosanna Supino; M Crosti; M Clerici; A Warlters; Loredana Cleris; Franco Zunino; Franca Formelli
Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expression.
International journal of cancer. Journal international du cancer 1996;65(4):491-7.
1996: Paola Perego; M Giarola; Sabina C Righetti; Rosanna Supino; C Caserini; Domenico Delia; Marco A Pierotti; T Miyashita; J C Reed; Franco Zunino
Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems.
Cancer research 1996;56(3):556-62.
1995: Linda Orlandi; Nadia Zaffaroni; Alessandra Bearzatto; A Costa; Rosanna Supino; Maurizio Vaglini; R Silvestrini
Effect of melphalan and hyperthermia on cell cycle progression and cyclin B1 expression in human melanoma cells.
Cell proliferation 1995;28(11):617-30.
1995: Monica Binaschi; Rosanna Supino; RA Gambetta; G Giaccone; Ennio Prosperi; Giovanni Capranico; I Cataldo; Franco Zunino
MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross-resistance.
International journal of cancer. Journal international du cancer 1995;62(1):84-9.
1994: Paola Perego; Giovanni Capranico; Rosanna Supino; Franco Zunino
Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types.
Anti-cancer drugs 1994;5(6):645-9.
1994: Rosanna Supino; C Cecchi; E Mapelli; O Sanfilippo
Modification of invasion and differentiation in human melanoma cell clones.
Melanoma research 1994;4(4):251-7.
1994: Giovanni Capranico; Rosanna Supino; Monica Binaschi; L Capolongo; M Grandi; A Suarato; Franco Zunino
Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance.
Molecular pharmacology 1994;45(5):908-15.
1994: E Mapelli; P Banfi; E Sala; Marialuisa Sensi; Rosanna Supino; Franco Zunino; RA Gambetta
Effect of protein kinase C inhibitors on invasiveness of human melanoma clones expressing different levels of protein kinase C isoenzymes.
International journal of cancer. Journal international du cancer 1994;57(2):281-6.
1993: Rosanna Supino; Monica Binaschi; Giovanni Capranico; RA Gambetta; Ennio Prosperi; E Sala; Franco Zunino
A study of cross-resistance pattern and expression of molecular markers of multidrug resistance in a human small-cell lung-cancer cell line selected with doxorubicin.
International journal of cancer. Journal international du cancer 1993;54(2):309-14.
1993: Ennio Prosperi; Rosanna Supino; Giovanni Bottiroli
Increased sensitivity of damaged DNA to digestion with nuclease S1 as assessed in single cells by flow cytometry.
Cytometry 1993;14(1):53-8.
1992: Rosanna Supino; E Mapelli; O Sanfilippo; L Silvestro
Biological and enzymatic features of human melanoma clones with different invasive potential.
Melanoma research 1992;2(5-6):377-84.
1992: Ennio Prosperi; E Sala; Claudia Negri; C Oliani; Rosanna Supino; G B Astraldi Ricotti; Giovanni Bottiroli
Topoisomerase II alpha and beta in human tumor cells grown in vitro and in vivo.
Anticancer research 1992;12(6B):2093-9.
1992: Rosanna Supino; Monica Rodolfo; M Mariani; E Mapelli
Heterogeneity and phenotypic instability of chemotherapeutic and immunologic sensitivity in murine and human melanoma cell clones.
Tumori 1992;78(1):5-9.
1992: Rosanna Supino; M Mariani; A Colombo; Ennio Prosperi; A C Croce; Giovanni Bottiroli
Comparative studies on the effects of doxorubicin and differentiation inducing agents on B16 melanoma cells.
European journal of cancer (Oxford, England : 1990) 1992;28A(4-5):778-83.
1990: Licia Rivoltini; Mario P Colombo; Rosanna Supino; D Ballinari; T Tsuruo; Giorgio Parmiani
Modulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line.
International journal of cancer. Journal international du cancer 1990;46(4):727-32.
1990: G Pratesi; Giovanni Capranico; Monica Binaschi; P De Isabella; S Pilotti; Rosanna Supino; Franco Zunino
Relationships among tumor responsiveness, cell sensitivity, doxorubicin cellular pharmacokinetics and drug-induced DNA alterations in two human small-cell lung cancer xenografts.
International journal of cancer. Journal international du cancer 1990;46(4):669-74.
1990: Andrea Anichini; Roberta Mortarini; Rosanna Supino; Giorgio Parmiani
Human melanoma cells with high susceptibility to cell-mediated lysis can be identified on the basis of ICAM-1 phenotype, VLA profile and invasive ability.
International journal of cancer. Journal international du cancer 1990;46(3):508-15.
1990: Ennio Prosperi; M C Giangaré; Rosanna Supino; Giovanni Bottiroli
Flow cytometric evaluation of DNA digestion with micrococcal nuclease on isolated HeLa nuclei.
Journal of microscopy 1990;159(Pt 3):255-63.
1990: M Mariani; Rosanna Supino
Morphological alterations induced by doxorubicin in B16 melanoma cells.
Cancer letters 1990;51(3):209-12.
1990: Monica Binaschi; Giovanni Capranico; P De Isabella; M Mariani; Rosanna Supino; S Tinelli; Franco Zunino
Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors.
International journal of cancer. Journal international du cancer 1990;45(2):347-52.
1990: Ennio Prosperi; M C Giangaré; Rosanna Supino; Giovanni Bottiroli
Parameters influencing the flow cytometric analysis of DNA sensitivity to nuclease S1.
Histochemistry 1990;93(4):417-21.
1989: Licia Rivoltini; Carlo Gambacorti-Passerini; Rosanna Supino; Giorgio Parmiani
Generation and partial characterization of melanoma sublines resistant to lymphokine activated killer (LAK) cells. Relevance to doxorubicin resistance.
International journal of cancer. Journal international du cancer 1989;43(5):880-5.
1989: Giovanni Capranico; P De Isabella; C Castelli; Rosanna Supino; G Parmiani; Franco Zunino
P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines.
British journal of cancer 1989;59(5):682-5.
1989: M Mariani; Ennio Prosperi; A Colombo; Rosanna Supino
Doxorubicin resistance circumvention by verapamil in B16 melanoma cells.
Anticancer research 1989;9(1):29-32.
1989: Ennio Prosperi; A C Croce; Rosanna Supino; Giovanni Bottiroli
Metabolic energy availability and proliferative activity in adriamycin-treated cells.
Anticancer research 1989;9(1):203-7.
1988: Carlo Gambacorti-Passerini; Licia Rivoltini; Marina Radrizzani; Rosanna Supino; M Mariani; Giorgio Parmiani
Susceptibility of human and murine drug-resistant tumor cells to the lytic activity of rIL2-activated lymphocytes (LAK).
Cancer metastasis reviews 1988;7(4):335-45.
1988: A C Croce; Giovanni Bottiroli; Ennio Prosperi; Rosanna Supino; P J Stoward
Limitations of the quantitative cytochemical assay of catechol oxidase in melanoma cells.
The Histochemical journal 1988;20(11):595-602.
1988: Carlo Gambacorti-Passerini; Licia Rivoltini; Rosanna Supino; M Mariani; Giorgio Parmiani
Differential lysis of melanoma clones by autologous recombinant interleukin 2-activated lymphocytes. Relationship with spontaneous resistance to doxorubicin (Dx).
International journal of cancer. Journal international du cancer 1988;42(4):544-8.
1988: Carlo Gambacorti-Passerini; Licia Rivoltini; Rosanna Supino; Monica Rodolfo; Marina Radrizzani; G Fossati; Giorgio Parmiani
Susceptibility of chemoresistant murine and human tumor cells to lysis by interleukin 2-activated lymphocytes.
Cancer research 1988;48(9):2372-6.
1988: Franca Formelli; Rosanna Supino; Loredana Cleris; M Mariani
Verapamil potentiation of doxorubicin resistance development in B16 melanoma cells both in vitro and in vivo.
British journal of cancer 1988;57(4):343-7.
1988: Rosanna Supino; M Mariani; Giovanni Capranico; A Colombo; G Parmiani
Doxorubicin cellular pharmacokinetics and DNA breakage in a multi-drug resistant B16 melanoma cell line.
British journal of cancer 1988;57(2):142-6.
1988: Rosanna Supino; M Mariani; Ennio Prosperi; G Parmiani
Lack of cross-resistance of a doxorubicin-resistant B16 melanoma line with 4'-deoxy-4'-iodo-doxorubicin.
Cancer chemotherapy and pharmacology 1988;21(3):251-4.
1987: Rosanna Supino; Nadia Gibelli; Rosanna Nano; Gabriella Pezzoni; Franco Zunino
In vitro and in vivo studies of poly-L-lysine as inducer of Friend leukemic cells differentiation.
Tumori 1987;73(5):431-6.
1987: Rosanna Supino; L Bardella; Nadia Gibelli; Gaetano Cairo; Luisa Schiaffonati
Interaction of heat with chemotherapy in vitro: effect on cell viability and protein synthesis in human and murine cell lines.
Tumori 1987;73(2):109-16.
1986: A C Croce; Ennio Prosperi; Rosanna Supino; Giovanni Bottiroli
Anthracycline-induced inhibition of membrane permeability functions dependent on metabolic energy.
British journal of cancer 1986;54(6):943-50.
1986: Rosanna Supino; Nadia Gibelli; F Zunino
Induction of differentiation of Friend murine erythroleukemia cells by poly-L-lysine and daunorubicin-poly-L-lysine conjugate.
Journal of the National Cancer Institute 1986;77(2):453-7.
1986: Ennio Prosperi; A C Croce; Giovanni Bottiroli; Rosanna Supino
Flow cytometric analysis of membrane permeability properties influencing intracellular accumulation and efflux of fluorescein.
Cytometry 1986;7(1):70-5.
1985: Rosanna Supino; Nadia Gibelli; I Galatulas; F Zunino
Influence of calcium and calcium-modulating agents on differentiation of murine erythroleukaemia cells.
Cell biology international reports 1985;9(12):1059-68.
1985: Ennio Prosperi; A C Croce; Giovanni Bottiroli; Rosanna Supino
Influence of daunorubicin on membrane permeability properties: detection by means of intracellular accumulation and efflux of fluorescein.
Chemico-biological interactions 1985;54(3):271-80.
1984: Franco Zunino; G Savi; FC Giuliani; RA Gambetta; Rosanna Supino; S Tinelli; Gabriella Pezzoni
Comparison of antitumor effects of daunorubicin covalently linked to poly-L-amino acid carriers.
European journal of cancer & clinical oncology 1984;20(3):421-5.
1983: A Bargiotti; A M Casazza; G Cassinelli; A Di Marco; S Penco; Graziella Pratesi; Rosanna Supino; A Zaccara; Franco Zunino; FM Arcamone
Synthesis, biological and biochemical properties of new anthracyclines modified in the aminosugar moiety.
Cancer chemotherapy and pharmacology 1983;10(2):84-9.
1983: Rosanna Supino; R Bossa; T Dasdia; I Galatulas; F Zunino
Enhancement of mitogenic stimuli by phosphatidylinositol.
Cancer letters 1983;17(3):257-62.
1983: Ennio Prosperi; A C Croce; Giovanni Bottiroli; T Dasdia; Rosanna Supino
Uptake kinetics and intracellular distribution of anthracyclines studied by laser cytofluorometry.
Basic and applied histochemistry 1983;27(2):117-27.
1982: R Bossa; I Galatulas; G Savi; Rosanna Supino; Franco Zunino
Reduction of lethal toxicity of doxorubicin by amrinone.
Tumori 1982;68(6):499-504.