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Young-Joon Surh

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
44
Na, Hye-Kyung
27
Kundu , Joydip
18
Chun, Kyung-Soo
17
Park, Kwan-Kyu
11
Miller, JA
10
Keum, Young-Sam
9
Li, Mei-Hua
9
Lee, Sang Sup
8
Lee, Hyong Joo
8
Jang, Jung-Hee
7
Hahm, Ki-Baik
7
Cha, Young-Nam
7
Kim, Eun-Hee
7
Oh, Tae Young
6
Liem, A

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Publications

TOP 3
Lee Mee-Hyun; Choi Bu Young; Kundu Joydeb Kumar; Shin Young Kee; Na Hye-Kyung; Surh Young-Joon
Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.
Choi Jin Woo; Um Jung Yeon; Kundu Joydeb Kumar; Surh Young-Joon; Kim Sunghoon
Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis.
Surh Young-Joon; Kundu Joydeb Kumar; Li Mei-Hua; Na Hye-Kyung; Cha Young-Nam
Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress.

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All Publications

2009: Lee Mee-Hyun; Choi Bu Young; Kundu Joydeb Kumar; Shin Young Kee; Na Hye-Kyung; Surh Young-Joon
Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.
Cancer research 2009;69(18):7449-58.
2009: Choi Jin Woo; Um Jung Yeon; Kundu Joydeb Kumar; Surh Young-Joon; Kim Sunghoon
Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis.
Carcinogenesis 2009;30(9):1638-44.
2009: Surh Young-Joon; Kundu Joydeb Kumar; Li Mei-Hua; Na Hye-Kyung; Cha Young-Nam
Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress.
Archives of pharmacal research 2009;32(8):1163-76.
2009: Kim Si-Young; Jun Tae-Won; Lee Young-Soo; Na Hye-Kyung; Surh Young-Joon; Song Wook
Effects of exercise on cyclooxygenase-2 expression and nuclear factor-kappaB DNA binding in human peripheral blood mononuclear cells.
Annals of the New York Academy of Sciences 2009;1171():464-71.
2009: Song Na-Young; Kim Do-Hee; Kim Eun-Hee; Na Hye-Kyung; Surh Young-Joon
15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells.
Annals of the New York Academy of Sciences 2009;1171():210-6.
2009: Kim Do-Hee; Kim Eun-Hee; Na Hye-Kyung; Surh Young-Joon
Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells.
Annals of the New York Academy of Sciences 2009;1171():202-9.
2009: Lee Mee-Hyun; Surh Young-Joon
eEF1A2 as a putative oncogene.
Annals of the New York Academy of Sciences 2009;1171():87-93.
2009: Kim Do-Hee; Kim Jung-Hyun; Kim Eun-Hee; Na Hye-Kyung; Cha Young-Nam; Chung Jin Ho; Surh Young-Joon
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
Carcinogenesis 2009;30(4):645-54.
2009: Park Sin-Aye; Na Hye-Kyung; Kim Eun-Hee; Cha Young-Nam; Surh Young-Joon
4-hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells via activation of IkappaB kinase: potential role of reactive oxygen species.
Cancer research 2009;69(6):2416-24.
2009: Lee Won-Hee; Choi Joon-Seok; Kim Hyun Young; Park Jeong-Hill; Lee Seung-Ki; Surh Young-Joon
Heat-processed neoginseng, KG-135, down-regulates G1 Cyclin-dependent kinase through the proteasome-mediated pathway in HeLa cells.
Oncology reports 2009;21(2):467-74.
2009: Farombi Ebenezer O; Shrotriya Sangeeta; Surh Young-Joon
Kolaviron inhibits dimethyl nitrosamine-induced liver injury by suppressing COX-2 and iNOS expression via NF-kappaB and AP-1.
Life sciences 2009;84(5-6):149-55.
2009: Kundu Joydeb Kumar; Hwang Dal-Mi; Lee Jung-Chul; Chang Eun-Jin; Shin Young Kee; Fujii Hajime; Sun Buxiang; Surh Young-Joon
Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-kappaB and C/EBP as potential targets.
Cancer letters 2009;273(1):86-97.
2009: Kundu Joydeb Kumar; Na Hye-Kyung; Surh Young-Joon
Ginger-derived phenolic substances with cancer preventive and therapeutic potential.
Forum of nutrition 2009;61():182-92.
2008: Kim Ji-Woo; Li Mei-Hua; Jang Jung-Hee; Na Hye-Kyung; Song Na-Young; Lee Chan; Johnson Jeffrey A; Surh Young-Joon
15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2.
Biochemical pharmacology 2008;76(11):1577-89.
2008: Kim Eun-Hee; Surh Young-Joon
The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis.
Biochemical pharmacology 2008;76(11):1544-53.
2008: Surh Young-Joon; Kundu Joydeb Kumar; Na Hye-Kyung
Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.
Planta medica 2008;74(13):1526-39.
2008: Kundu Joydeb Kumar; Surh Young-Joon
Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives.
Cancer letters 2008;269(2):243-61.
2008: Na Hye-Kyung; Kim Eun-Hee; Jung Joo-Hee; Lee Hyun-Hee; Hyun Jin-Won; Surh Young-Joon
(-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells.
Archives of biochemistry and biophysics 2008;476(2):171-7.
2008: Kundu Joydeb Kumar; Surh Young-Joon
Inflammation: gearing the journey to cancer.
Mutation research 2008;659(1-2):15-30.
2008: Kim Eun-Hee; Na Hye-Kyung; Kim Do-Hee; Park Sin-Aye; Kim Ha-Na; Song Na-Young; Surh Young-Joon
15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS.
Carcinogenesis 2008;29(4):688-95.
2008: Na Hye-Kyung; Surh Young-Joon
Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1271-8.
2008: Farombi E Olatunde; Shrotriya Sangeeta; Na Hye-Kyung; Kim Sung-Hoon; Surh Young-Joon
Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1279-87.
2008: Kundu Joydeb Kumar; Chang Eun-Jin; Fujii Hajime; Sun Buxiang; Surh Young-Joon
Oligonol inhibits UVB-induced COX-2 expression in HR-1 hairless mouse skin--AP-1 and C/EBP as potential upstream targets.
Photochemistry and photobiology 2008;84(2):399-406.
2008: Surh Young-Joon; Na Hye-Kyung
NF-kappaB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals.
Genes & nutrition 2008;2(4):313-7.
2008: Kwon Dae Young; Surh Young-Joon
Editorial.
Genes & nutrition 2008;2(4):311-2.
2008: Kim Jung-Hwan; Na Hye-Kyung; Pak Youngmi K; Lee Yun-Sil; Lee Su-Jae; Moon Aree; Surh Young-Joon
Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells.
Chemico-biological interactions 2008;171(2):133-41.
2008: Kim Hyun Soo; Kundu Joydeb Kumar; Lee Jeong-Sang; Oh Tae-Young; Na Hye-Kyung; Surh Young-Joon
Chemopreventive effects of the standardized extract (DA-9601) of Artemisia asiatica on azoxymethane-initiated and dextran sulfate sodium-promoted mouse colon carcinogenesis.
Nutrition and cancer 2008;60 Suppl 1():90-7.
2008: Surh Young-Joon
NF-kappa B and Nrf2 as potential chemopreventive targets of some anti-inflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative activities.
Asia Pacific journal of clinical nutrition 2008;17 Suppl 1():269-72.
2008: Na Hye-Kyung; Surh Young-Joon
The antitumor ether lipid edelfosine (ET-18-O-CH3) induces apoptosis in H-ras transformed human breast epithelial cells: by blocking ERK1/2 and p38 mitogen-activated protein kinases as potential targets.
Asia Pacific journal of clinical nutrition 2008;17 Suppl 1():204-7.
2007: Park So Young; Kim Eun Ji; Shin Hyun-Kyung; Kwon Dae Young; Kim Myung Sunny; Surh Young-Joon; Park Jung Han Yoon
Induction of apoptosis in HT-29 colon cancer cells by phloretin.
Journal of medicinal food 2007;10(4):581-6.
2007: Joung Eun-Joo; Li Mei-Hua; Lee Hee Geum; Somparn Nuntiya; Jung Young Suk; Na Hye-Kyung; Kim Sung-Hoon; Cha Young-Nam; Surh Young-Joon
Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target.
Antioxidants & redox signaling 2007;9(12):2087-98.
2007: Park So-Hyun; Jang Jung-Hee; Li Mei-Hua; Na Hye-Kyung; Cha Young-Nam; Surh Young-Joon
Nrf2-mediated heme oxygenase-1 induction confers adaptive survival response to tetrahydropapaveroline-induced oxidative PC12 cell death.
Antioxidants & redox signaling 2007;9(12):2075-86.
2007: Lee Ki Won; Kang Nam Joo; Rogozin Evgeny A; Kim Hong-Gyum; Cho Yong Yeon; Bode Ann M; Lee Hyong Joo; Surh Young-Joon; Bowden G Tim; Dong Zigang
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1.
Carcinogenesis 2007;28(9):1918-27.
2007: Li Mei-Hua; Jang Jung-Hee; Na Hye-Kyung; Cha Young-Nam; Surh Young-Joon
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.
The Journal of biological chemistry 2007;282(39):28577-86.
2007: Surh Young-Joon; Kundu Joydeb Kumar
Cancer preventive phytochemicals as speed breakers in inflammatory signaling involved in aberrant COX-2 expression.
Current cancer drug targets 2007;7(5):447-58.
2007: Lee Jung-Chul; Kundu Joydeb K; Hwang Dal-Mi; Na Hye-Kyung; Surh Young-Joon
Humulone inhibits phorbol ester-induced COX-2 expression in mouse skin by blocking activation of NF-kappaB and AP-1: IkappaB kinase and c-Jun-N-terminal kinase as respective potential upstream targets.
Carcinogenesis 2007;28(7):1491-8.
2007: Kang Kyoung Ah; Lee Kyoung Hwa; Park Jae Woo; Lee Nam Ho; Na Hye Kyung; Surh Young Joon; You Ho Jin; Chung Myung Hee; Hyun Jin Won
Triphlorethol-A induces heme oxygenase-1 via activation of ERK and NF-E2 related factor 2 transcription factor.
FEBS letters 2007;581(10):2000-8.
2007: Kim Jin-Kyoung; Kim Younghwa; Na Kwang-Min; Surh Young-Joon; Kim Tae-Yoon
[6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo.
Free radical research 2007;41(5):603-14.
2007: Jeon Soung Hoo; Yoon Ju-Yong; Park Young-Nyun; Jeong Woo-Jeong; Kim Sewoon; Jho Eek-Hoon; Surh Young-Joon; Choi Kang-Yell
Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.
The Journal of biological chemistry 2007;282(19):14482-92.
2007: Jun Hye-Seung; Park Taesun; Lee Chang Ki; Kang Mi Kyung; Park Mi Sun; Kang Ho Il; Surh Young-Joon; Kim Ok Hee
Capsaicin induced apoptosis of B16-F10 melanoma cells through down-regulation of Bcl-2.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(5):708-15.
2007: Hwang Dal-Mi; Kundu Joydeb Kumar; Shin Jun-Wan; Lee Jung-Chul; Lee Hyong Joo; Surh Young-Joon
cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt.
Carcinogenesis 2007;28(2):363-71.
2007: Park Sin-Aye; Kim Eun-Hee; Na Hye-Kyung; Surh Young-Joon
KG-135 inhibits COX-2 expression by blocking the activation of JNK and AP-1 in phorbol ester-stimulated human breast epithelial cells.
Annals of the New York Academy of Sciences 2007;1095():545-53.
2007: Lee Jeong-Sang; Kim Hyun-Soo; Hahm Ki-Baik; Sohn Mi-Won; Yoo Moohi; Johnson Jeffrey A; Surh Young-Joon
Inhibitory effects of 7-carboxymethyloxy-3',4',5-trimethoxyflavone (DA-6034) on Helicobacter pylori-induced NF-kappa B activation and iNOS expression in AGS cells.
Annals of the New York Academy of Sciences 2007;1095():527-35.
2007: Kundu Joydeb Kumar; Surh Young-Joon
Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kappa B and CREB in mouse skin: role of p38 MAPK.
Annals of the New York Academy of Sciences 2007;1095():504-12.
2007: Kim Min-Jung; Kim Do-Hee; Lee Ki Won; Yoon Do-Young; Surh Young-Joon
Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species.
Annals of the New York Academy of Sciences 2007;1095():483-95.
2007: Chen Chu-Yue; Jang Jung-Hee; Park Mi Hyun; Hwang Sung Joo; Surh Young-Joon; Park Ock Jin
Attenuation of Abeta-induced apoptosis of plant extract (Saengshik) mediated by the inhibition of mitochondrial dysfunction and antioxidative effect.
Annals of the New York Academy of Sciences 2007;1095():399-411.
2007: Kim Eun Ji; Park So Young; Shin Hyun-Kyung; Kwon Dae Young; Surh Young-Joon; Park Jung Han Yoon
Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells.
The Journal of nutrition 2007;137(1):31-6.
2007: Surh Young-Joon; Chun Kyung-Soo
Cancer chemopreventive effects of curcumin.
Advances in experimental medicine and biology 2007;595():149-72.
2006: Kim Eun-Hee; Na Hye-Kyung; Surh Young-Joon
Upregulation of VEGF by 15-deoxy-Delta12,14-prostaglandin J2 via heme oxygenase-1 and ERK1/2 signaling in MCF-7 cells.
Annals of the New York Academy of Sciences 2006;1090():375-84.
2006: Kundu Joydeb Kumar; Shin Young Kee; Surh Young-Joon
Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets.
Biochemical pharmacology 2006;72(11):1506-15.
2006: Kim Eun-Hee; Surh Young-Joon
15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors.
Biochemical pharmacology 2006;72(11):1516-28.
2006: Hwang Jin-Taek; Kim Young Min; Surh Young-Joon; Baik Haing Woon; Lee Seong-Kyu; Ha Joohun; Park Ock Jin
Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells.
Cancer research 2006;66(20):10057-63.
2006: Li Mei-Hua; Cha Young-Nam; Surh Young-Joon
Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells.
Free radical biology & medicine 2006;41(7):1079-91.
2006: Lee Ki Won; Kim Mi-Sung; Kang Nam Joo; Kim Do-Hee; Surh Young-Joon; Lee Hyong Joo; Moon Aree
H-Ras selectively up-regulates MMP-9 and COX-2 through activation of ERK1/2 and NF-kappaB: an implication for invasive phenotype in rat liver epithelial cells.
International journal of cancer. Journal international du cancer 2006;119(8):1767-75.
2006: Farombi Ebenezer Olatunde; Surh Young Joon
Heme oxygenase-1 as a potential therapeutic target for hepatoprotection.
Journal of biochemistry and molecular biology 2006;39(5):479-91.
2006: Kundu Joydeb Kumar; Shin Young Kee; Kim Sung Hoon; Surh Young-Joon
Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity.
Carcinogenesis 2006;27(7):1465-74.
2006: Chun Kyung-Soo; Kundu Joydeb Kumar; Park Kwang-Kyun; Chung Won-Yoon; Surh Young-Joon
Inhibition of Phorbol Ester-induced Mouse Skin Tumor Promotion and COX-2 Expression by Celecoxib: C/EBP as a Potential Molecular Target.
Cancer research and treatment : official journal of Korean Cancer Association 2006;38(3):152-8.
2006: Na Hye-Kyung; Surh Young-Joon
Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection.
Molecular carcinogenesis 2006;45(6):368-80.
2006: Lee Ki Won; Kundu Joydeb Kumar; Kim Sue Ok; Chun Kyung-Soo; Lee Hyong Joo; Surh Young-Joon
Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kappaB and MAPKs in mouse skin in vivo.
The Journal of nutrition 2006;136(5):1150-5.
2006: Li Mei-Hua; Cha Young-Nam; Surh Young-Joon
Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential.
Biochemical and biophysical research communications 2006;342(3):984-90.
2006: Park Ki-Sook; Jeon Soung Hoo; Kim Sung-Eun; Bahk Young-Yil; Holmen Sheri L; Williams Bart O; Chung Kwang-Chul; Surh Young-Joon; Choi Kang-Yell
APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Journal of cell science 2006;119(Pt 5):819-27.
2006: Na Hye-Kyung; Surh Young-Joon
Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate.
Molecular nutrition & food research 2006;50(2):152-9.
2006: Lee Soo Jin; Sakurai Hiroaki; Koizumi Keiichi; Song Gyu Yong; Bae Yong Soo; Kim Hyung-Min; Kang Kyung-Sun; Surh Young-Joon; Saiki Ikuo; Kim Sung Hoon
MAPK regulation and caspase activation are required in DMNQ S-52 induced apoptosis in Lewis lung carcinoma cells.
Cancer letters 2006;233(1):57-67.
2006: Kim Jung-Hwan; Lee Ki Won; Lee Min-Won; Lee Hyong Joo; Kim Sung-Hoon; Surh Young-Joon
Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target.
FEBS letters 2006;580(2):385-92.
2006: Kundu Joydeb Kumar; Choi Kang-Yell; Surh Young-Joon
beta-Catenin-mediated signaling: a novel molecular target for chemoprevention with anti-inflammatory substances.
Biochimica et biophysica acta 2006;1765(1):14-24.
2005: Surh Young-Joon; Kundu Joydeb Kumar; Na Hye-Kyung; Lee Jeong-Sang
Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicals.
The Journal of nutrition 2005;135(12 Suppl):2993S-3001S.
2005: Kundu Joydeb Kumar; Surh Young-Joon
Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals.
Mutation research 2005;591(1-2):123-46.
2005: Prawan Auemduan; Kundu Joydeb K; Surh Young-Joon
Molecular basis of heme oxygenase-1 induction: implications for chemoprevention and chemoprotection.
Antioxidants & redox signaling 2005;7(11-12):1688-703.
2005: Lee Ki Won; Kim Jung-Hwan; Lee Hyong Joo; Surh Young-Joon
Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells.
Antioxidants & redox signaling 2005;7(11-12):1612-20.
2005: Na Hye-Kyung; Inoue Hiroyasu; Surh Young-Joon
ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells.
FEBS letters 2005;579(27):6279-87.
2005: Lee Jeong-Sang; Oh Tae-Young; Kim Young-Kyung; Baik Joo-Hyun; So Sung; Hahm Ki-Baik; Surh Young-Joon
Protective effects of green tea polyphenol extracts against ethanol-induced gastric mucosal damages in rats: stress-responsive transcription factors and MAP kinases as potential targets.
Mutation research 2005;579(1-2):214-24.
2005: Li Mei-Hua; Jang Jung-Hee; Surh Young-Joon
Nitric oxide induces apoptosis via AP-1-driven upregulation of COX-2 in rat pheochromocytoma cells.
Free radical biology & medicine 2005;39(7):890-9.
2005: Chen Zhi-Hua; Na Hye-Kyung; Hurh Yeon-Jin; Surh Young-Joon
4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-kappaB and ERK/MAPK.
Toxicology and applied pharmacology 2005;208(1):46-56.
2005: Huh Jeong-Eun; Lee Eun-Ok; Kim Min-Seok; Kang Kyung-Sun; Kim Cheol-Ho; Cha Bae-Cheon; Surh Young-Joon; Kim Sung-Hoon
Penta-O-galloyl-beta-D-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways.
Carcinogenesis 2005;26(8):1436-45.
2005: Jang Jung-Hee; Surh Young-Joon
Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway.
Free radical biology & medicine 2005;38(12):1604-13.
2005: Lee Jeong-Sang; Surh Young-Joon
Nrf2 as a novel molecular target for chemoprevention.
Cancer letters 2005;224(2):171-84.
2005: Jang Jung-Hee; Surh Young-Joon
AP-1 mediates beta-amyloid-induced iNOS expression in PC12 cells via the ERK2 and p38 MAPK signaling pathways.
Biochemical and biophysical research communications 2005;331(4):1421-8.
2005: Chen Chu-Yue; Jang Jung-Hee; Li Mei-Hua; Surh Young-Joon
Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells.
Biochemical and biophysical research communications 2005;331(4):993-1000.
2005: Kim Sue Ok; Kundu Joydeb Kumar; Shin Young Kee; Park Jin-Hong; Cho Myung-Haing; Kim Tae-Yoon; Surh Young-Joon
[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin.
Oncogene 2005;24(15):2558-67.
2005: Lee Ji-Yoon; Shin Jun-Wan; Chun Kyung-Soo; Park Kwang-Kyun; Chung Won-Yoon; Bang Yung-Jue; Sung Jong-Hwan; Surh Young-Joon
Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin.
Carcinogenesis 2005;26(2):359-67.
2005: Surh Young-Joon; Kundu Joydeb Kumar
Signal transduction network leading to COX-2 induction: a road map in search of cancer chemopreventives.
Archives of pharmacal research 2005;28(1):1-15.
2005: Kundu Joydeb Kumar; Mossanda Kensese S; Na Hye-Kyung; Surh Young-Joon
Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets.
Cancer letters 2005;218(1):21-31.
2005: Kim Do-Hee; Na Hye-Kyung; Oh Tae Young; Shin Chang-Yell; Surh Young-Joon
Eupatilin inhibits proliferation of ras-transformed human breast epithelial (MCF-10A-ras) cells.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2005;24(4):251-9.
2005: Yoo Byung-Moo; Oh Tae-Young; Kim Young-Bae; Yeo Marie; Lee Jeong-Sang; Surh Young Joon; Ahn Byoung-Ok; Kim Wook-Hwan; Sohn Seonghyang; Kim Jin-Hong; Hahm Ki-Baik
Novel antioxidant ameliorates the fibrosis and inflammation of cerulein-induced chronic pancreatitis in a mouse model.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2005;5(2-3):165-76.
2004: Lee Ki Won; Chun Kyung-Soo; Lee Jeong-Sang; Kang Kyung-Sun; Surh Young-Joon; Lee Hyong Joo
Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester.
Annals of the New York Academy of Sciences 2004;1030():501-7.
2004: Kim Eun-Hee; Kim Do-Hee; Na Hye-Kyung; Surh Young-Joon
Effects of cyclopentenone prostaglandins on the expression of heme oxygenase-1 in MCF-7 cells.
Annals of the New York Academy of Sciences 2004;1030():493-500.
2004: Li Mei-Hua; Jang Jung-Hee; Sun Buxiang; Surh Young-Joon
Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death.
Annals of the New York Academy of Sciences 2004;1030():317-29.
2004: Hurh Yeon-Jin; Chen Zhi-Hua; Na Hye-Kyung; Han Soon-Young; Surh Young-Joon
2-Hydroxyestradiol induces oxidative DNA damage and apoptosis in human mammary epithelial cells.
Journal of toxicology and environmental health. Part A 2004;67(23-24):1939-53.
2004: Kundu Joydeb Kumar; Surh Young-Joon
Molecular basis of chemoprevention by resveratrol: NF-kappaB and AP-1 as potential targets.
Mutation research 2004;555(1-2):65-80.
2004: Han Seong-Su; Kim Kihyun; Hahm Eun-Ryeong; Lee Sook J; Surh Young-Joon; Park Hye K; Kim Won S; Jung Chul W; Lee Mark H; Park Keunchil; Yang Jung-Hyun; Yoon Sung-Soo; Riordan Neil H; Riordan Hugh D; Kimler Bruce F; Park Chan H; Lee Je-Ho; Park Seyeon
L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60.
Journal of cellular biochemistry 2004;93(2):257-70.
2004: Lim So-Young; Jang Jung-Hee; Na Hye-Kyung; Lu Shelly C; Rahman Irfan; Surh Young-Joon
15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis.
The Journal of biological chemistry 2004;279(44):46263-70.
2004: Chen Zhi-Hua; Hurh Yeon-Jin; Na Hye-Kyung; Kim Jung-Hwan; Chun Young-Jin; Kim Dong-Hyun; Kang Kyung-Sun; Cho Myung-Haing; Surh Young-Joon
Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells.
Carcinogenesis 2004;25(10):2005-13.
2004: Chun Kyung-Soo; Surh Young-Joon
Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention.
Biochemical pharmacology 2004;68(6):1089-100.
2004: Kim Do-Hee; Na Hye-Kyung; Oh Tae Young; Kim Won-Bae; Surh Young-Joon
Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces cell cycle arrest in ras-transformed human mammary epithelial cells.
Biochemical pharmacology 2004;68(6):1081-7.
2004: Jang Jung-Hee; Surh Young-Joon
Bcl-2 attenuation of oxidative cell death is associated with up-regulation of gamma-glutamylcysteine ligase via constitutive NF-kappaB activation.
The Journal of biological chemistry 2004;279(37):38779-86.
2004: Kim Su-Hyeong; Song Sang-Hyun; Kim Sang-Gyun; Chun Kyung-Soo; Lim So-Young; Na Hye-Kyung; Kim Jae Weon; Surh Young-Joon; Bang Yung-Jue; Song Yong-Sang
Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kappaB as a possible target.
Journal of cancer research and clinical oncology 2004;130(9):551-60.
2004: Jang Jung-Hee; Surh Young-Joon
Bcl-2 protects against Abeta(25-35)-induced oxidative PC12 cell death by potentiation of antioxidant capacity.
Biochemical and biophysical research communications 2004;320(3):880-6.
2004: Murakami Akira; Tanaka Takuji; Lee Ji-Yoon; Surh Young-Joon; Kim Ha Won; Kawabata Kyuichi; Nakamura Yoshimasa; Jiwajinda Suratwadee; Ohigashi Hajime
Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice.
International journal of cancer. Journal international du cancer 2004;110(4):481-90.
2004: Shin Mi-Hyun; Jang Jung-Hee; Surh Young-Joon
Potential roles of NF-kappaB and ERK1/2 in cytoprotection against oxidative cell death induced by tetrahydropapaveroline.
Free radical biology & medicine 2004;36(9):1185-94.
2004: Chun Kyung-Soo; Kim Su-Hyeong; Song Yong-Sang; Surh Young-Joon
Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin.
Carcinogenesis 2004;25(5):713-22.
2004: Park Ock Jin; Surh Young-Joon
Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies.
Toxicology letters 2004;150(1):43-56.
2004: Chun Kyung-Soo; Cha Hyun-Ho; Shin Jun-Wan; Na Hye-Kyung; Park Kwang-Kyun; Chung Won-Yoon; Surh Young-Joon
Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-kappaB.
Carcinogenesis 2004;25(3):445-54.
2004: Jang Jung-Hee; Aruoma Okezie I; Jen Ling-Sun; Chung Hae Young; Surh Young-Joon
Ergothioneine rescues PC12 cells from beta-amyloid-induced apoptotic death.
Free radical biology & medicine 2004;36(3):288-99.
2004: Jang Jung-Hee; Surh Young-Joon
Possible role of NF-kappaB in Bcl-X(L) protection against hydrogen peroxide-induced PC12 cell death.
Redox report : communications in free radical research 2004;9(6):343-8.
2004: Na Hye-Kyung; Mossanda Kensese S; Lee Ji-Yoon; Surh Young-Joon
Inhibition of phorbol ester-induced COX-2 expression by some edible African plants.
BioFactors (Oxford, England) 2004;21(1-4):149-53.
2004: Surh Young-Joon; Na Hye-Kyung; Lee Seung Sei
Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicals.
BioFactors (Oxford, England) 2004;21(1-4):103-8.
2004: Kundu Joydeb Kumar; Chun Kyung-Soo; Kim Sue O; Surh Young-Joon
Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets.
BioFactors (Oxford, England) 2004;21(1-4):33-9.
2004: Kim Sue Ok; Chun Kyung-Soo; Kundu Joydeb Kumar; Surh Young-Joon
Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kappaB and p38 MAPK in mouse skin.
BioFactors (Oxford, England) 2004;21(1-4):27-31.
2003: Lim So-Young; Jang Jung-Hee; Surh Young-Joon
Induction of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma during nitric oxide-induced apoptotic PC12 cell death.
Annals of the New York Academy of Sciences 2003;1010():648-58.
2003: Yuan Lan; Wagatsuma Chihiro; Sun Buxiang; Kim Jung-Hwan; Surh Young-Joon
The role of beta-glucuronidase in induction of apoptosis by genistein combined polysaccharide (GCP) in xenogeneic mice bearing human mammary cancer cells.
Annals of the New York Academy of Sciences 2003;1010():347-9.
2003: Lee Ki Won; Lee Hyong Joo; Surh Young-Joon; Lee Chang Yong
Vitamin C and cancer chemoprevention: reappraisal.
The American journal of clinical nutrition 2003;78(6):1074-8.
2003: Soh Yunjo; Shin Mi-Hyun; Lee Jeong-Sang; Jang Jung-Hee; Kim Ok Hee; Kang Hoil; Surh Young-Joon
Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline.
Mutation research 2003;544(2-3):129-42.
2003: Kundu Joydeb Kumar; Na Hye-Kyung; Chun Kyung-Soo; Kim Young-Kyung; Lee Sang Jun; Lee Sang Sup; Lee Ok-Sub; Sim Young-Chul; Surh Young-Joon
Inhibition of phorbol ester-induced COX-2 expression by epigallocatechin gallate in mouse skin and cultured human mammary epithelial cells.
The Journal of nutrition 2003;133(11 Suppl 1):3805S-3810S.
2003: Kim Young-Ho; Park Jong-Wook; Lee Jai-Youl; Surh Young-Joon; Kwon Taeg Kyu
Bcl-2 overexpression prevents daunorubicin-induced apoptosis through inhibition of XIAP and Akt degradation.
Biochemical pharmacology 2003;66(9):1779-86.
2003: Surh Young-Joon
Cancer chemoprevention with dietary phytochemicals.
Nature reviews. Cancer 2003;3(10):768-80.
2003: Na Hye-Kyung; Surh Young-Joon
Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands as bifunctional regulators of cell proliferation.
Biochemical pharmacology 2003;66(8):1381-91.
2003: Jang Jung-Hee; Surh Young-Joon
Potentiation of cellular antioxidant capacity by Bcl-2: implications for its antiapoptotic function.
Biochemical pharmacology 2003;66(8):1371-9.
2003: Shin Chan Young; Shin Jieun; Kim Byung-Moon; Wang Myeong-Hyeon; Jang Jung-Hee; Surh Young-Joon; Oh Uhtaek
Essential role of mitochondrial permeability transition in vanilloid receptor 1-dependent cell death of sensory neurons.
Molecular and cellular neurosciences 2003;24(1):57-68.
2003: Chun Kyung-Soo; Keum Young-Sam; Han Seong Su; Song Yong-Sang; Kim Su-Hyeong; Surh Young-Joon
Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.
Carcinogenesis 2003;24(9):1515-24.
2003: Hahm K B; Kim D H; Lee K M; Lee J S; Surh Y J; Kim Y B; Yoo B M; Kim J H; Joo H J; Cho Y K; Nam K T; Cho S W
Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice.
Alimentary pharmacology & therapeutics 2003;18 Suppl 1():24-38.
2003: Jang Jung-Hee; Surh Young-Joon
Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death.
Free radical biology & medicine 2003;34(8):1100-10.
2003: Keum Young-Sam; Han Seong Su; Chun Kyung-Soo; Park Kwang-Kyun; Park Jeong-Hill; Lee Seung Ki; Surh Young-Joon
Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-kappaB activation and tumor promotion.
Mutation research 2003;523-524():75-85.
2003: Yuan Lan; Wagatsuma Chihiro; Yoshida Mayumi; Miura Takehito; Mukoda Tomomi; Fujii Hajime; Sun Buxiang; Kim Jung-Hwan; Surh Young-Joon
Inhibition of human breast cancer growth by GCP (genistein combined polysaccharide) in xenogeneic athymic mice: involvement of genistein biotransformation by beta-glucuronidase from tumor tissues.
Mutation research 2003;523-524():55-62.
2003: Surh Young-Joon; Ferguson Lynnette R
Dietary and medicinal antimutagens and anticarcinogens: molecular mechanisms and chemopreventive potential--highlights of a symposium.
Mutation research 2003;523-524():1-8.
2003: Kang Hye-Jung; Soh Yunjo; Kim Mi-Sung; Lee Eun-Jung; Surh Young-Joon; Kim Hyeong-Reh Choi; Kim Seung Hee; Moon Aree
Roles of JNK-1 and p38 in selective induction of apoptosis by capsaicin in ras-transformed human breast epithelial cells.
International journal of cancer. Journal international du cancer 2003;103(4):475-82.
2003: Hahm Ki Baik; Song Young Joon; Oh Tae Young; Lee Jeong Sang; Surh Young-Joon; Kim Young Bae; Yoo Byung Moo; Kim Jin Hong; Han Sang Uk; Nahm Ki Taik; Kim Myung-Wook; Kim Dae Yong; Cho Sung Won
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?
Journal of biochemistry and molecular biology 2003;36(1):82-94.
2002: Surh Young-Joon; Lee Ji-Yoon; Choi Kang-Ju; Ko Sung-Ryong
Effects of selected ginsenosides on phorbol ester-induced expression of cyclooxygenase-2 and activation of NF-kappaB and ERK1/2 in mouse skin.
Annals of the New York Academy of Sciences 2002;973():396-401.
2002: Jang Jung-Hee; Surh Young-Joon
beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase.
Annals of the New York Academy of Sciences 2002;973():228-36.
2002: Na Hye-Kyung; Surh Young-Joon
Induction of cyclooxygenase-2 in Ras-transformed human mammary epithelial cells undergoing apoptosis.
Annals of the New York Academy of Sciences 2002;973():153-60.
2002: Surh Young-Joon
More than spice: capsaicin in hot chili peppers makes tumor cells commit suicide.
Journal of the National Cancer Institute 2002;94(17):1263-5.
2002: Han Seong-Su; Keum Young-Sam; Chun Kyung-Soo; Surh Young-Joon
Suppression of phorbol ester-induced NF-kappaB activation by capsaicin in cultured human promyelocytic leukemia cells.
Archives of pharmacal research 2002;25(4):475-9.
2002: Seo Hyo-Joung; Park Kwang-Kyun; Han Seong Su; Chung Won-Yoon; Son Mi-Won; Kim Won-Bae; Surh Young-Joon
Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin.
International journal of cancer. Journal international du cancer 2002;100(4):456-62.
2002: Surh Young-Joon
Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(8):1091-7.
2002: Han Seong-Su; Keum Young-Sam; Seo Hyo-Joung; Surh Young-Joon
Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells.
Journal of biochemistry and molecular biology 2002;35(3):337-42.
2002: Surh Young-Joon; Jung Youn-Joo; Jang Jung-Hee; Lee Jeong-Sang; Yoon Hye-Ran
Iron enhancement of oxidative DNA damage and neuronal cell death induced by salsolinol.
Journal of toxicology and environmental health. Part A 2002;65(5-6):473-88.
2002: Keum Young Sam; Kim Jin; Lee Keun Hyung; Park Kwang Kyun; Surh Young Joon; Lee Jong Min; Lee Sang Sup; Yoon Jung Hoon; Joo So Yeon; Cha In Ho; Yook Jong In
Induction of apoptosis and caspase-3 activation by chemopreventive [6]-paradol and structurally related compounds in KB cells.
Cancer letters 2002;177(1):41-7.
2002: Chun Kyung-Soo; Park Kwang-Kyun; Lee Jeewoo; Kang Myungshin; Surh Young-Joon
Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae).
Oncology research 2002;13(1):37-45.
2002: Hahm Ki-Baik; Lim Ho-Yeong; Sohn Seongbyang; Kwon Hyuk-Jae; Lee K-Myung; Lee Jeong-Sang; Surh Young-Joon; Kim Young-Bae; Joo Hee-Jae; Kim Won-Seok; Cho Seung-Won
In vitro evidence of the role of COX-2 in attenuating gastric inflammation and promoting gastric carcinogenesis.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2002;21(2):165-76.
2002: Chun Kyung-Soo; Kang Jee-Young; Kim Ok Hee; Kang Hoil; Surh Young-Joon
Effects of yakuchinone A and yakuchinone B on the phorbol ester-induced expression of COX-2 and iNOS and activation of NF-kappaB in mouse skin.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 2002;21(2):131-9.
2001: Surh Y J; Na H K; Lee J Y; Keum Y S
Molecular mechanisms underlying anti-tumor promoting activities of heat-processed Panax ginseng C.A. Meyer.
Journal of Korean medical science 2001;16 Suppl():S38-41.
2001: Seo H J; Surh Y J
Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human promyelocytic leukemia cells.
Mutation research 2001;496(1-2):191-8.
2001: Jang J H; Surh Y J
Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells.
Mutation research 2001;496(1-2):181-90.
2001: Surh Y J; Chun K S; Cha H H; Han S S; Keum Y S; Park K K; Lee S S
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation.
Mutation research 2001;480-481():243-68.
2001: Lee J S; Oh T Y; Ahn B O; Cho H; Kim W B; Kim Y B; Surh Y J; Kim H J; Hahm K B
Involvement of oxidative stress in experimentally induced reflux esophagitis and Barrett's esophagus: clue for the chemoprevention of esophageal carcinoma by antioxidants.
Mutation research 2001;480-481():189-200.
2001: Jung Y; Surh Y
Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid.
Free radical biology & medicine 2001;30(12):1407-17.
2001: Jung Y J; Youn J Y; Ryu J C; Surh Y J
Salsolinol, a naturally occurring tetrahydroisoquinoline alkaloid, induces DNA damage and chromosomal aberrations in cultured Chinese hamster lung fibroblast cells.
Mutation research 2001;474(1-2):25-33.
2001: Han S S; Keum Y S; Seo H J; Chun K S; Lee S S; Surh Y J
Capsaicin suppresses phorbol ester-induced activation of NF-kappaB/Rel and AP-1 transcription factors in mouse epidermis.
Cancer letters 2001;164(2):119-26.
2000: Keum Y S; Park K K; Lee J M; Chun K S; Park J H; Lee S K; Kwon H; Surh Y J
Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng.
Cancer letters 2000;150(1):41-8.
2000: Surh Y J; Han S S; Keum Y S; Seo H J; Lee S S
Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1.
BioFactors (Oxford, England) 2000;12(1-4):107-12.
1999: Lee E; Kong G; Lee S J; Kim N D; Surh Y J
2-(allylthio)pyrazine suppresses the growth and proliferation of human promyelocytic leukemia (HL-60) cells via induction of apoptosis.
Anticancer research 1999;19(5B):4073-80.
1999: Kong G; Lee S J; Kim H J; Surh Y J; Kim N D
Induction of granulocytic differentiation in acute promyelocytic leukemia cells (HL-60) by 2-(allylthio) pyrazine.
Cancer letters 1999;144(1):1-8.
1999: Surh Y
Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.
Mutation research 1999;428(1-2):305-27.
1999: Ha T G; Mar W C; Kim S G; Surh Y J; Kim N D
Enhancement of biliary excretion of aflatoxin B(1) and suppression of hepatic ornithine decarboxylase activity by 2-(allylthio)pyrazine in rats.
Mutation research 1999;428(1-2):59-67.
1999: Chun K S; Sohn Y; Kim H S; Kim O H; Park K K; Lee J M; Moon A; Lee S S; Surh Y J
Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin.
Mutation research 1999;428(1-2):49-57.
1999: Surh Y J; Hurh Y J; Kang J Y; Lee E; Kong G; Lee S J
Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells.
Cancer letters 1999;140(1-2):1-10.
1999: Surh Y J; Kim S G; Liem A; Lee J W; Miller J A
Inhibitory effects of isopropyl-2-(1,3-dithietane-2-ylidene)-2- [N-(4-methylthiazol-2-yl)carbamoyl]acetate (YH439) on benzo[a]pyrene-induced skin carcinogenesis and micronucleated reticulocyte formation in mice.
Mutation research 1999;423(1-2):149-53.
1999: Surh Y J; Park K K; Chun K S; Lee L J; Lee E; Lee S S
Anti-tumor-promoting activities of selected pungent phenolic substances present in ginger.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1999;18(2):131-9.
1998: Lee E; Surh Y J
Induction of apoptosis in HL-60 cells by pungent vanilloids, [6]-gingerol and [6]-paradol.
Cancer letters 1998;134(2):163-8.
1998: Park K K; Chun K S; Yook J I; Surh Y J
Lack of tumor promoting activity of capsaicin, a principal pungent ingredient of red pepper, in mouse skin carcinogenesis.
Anticancer research 1998;18(6A):4201-5.
1998: Lee E; Park K K; Lee J M; Chun K S; Kang J Y; Lee S S; Surh Y J
Suppression of mouse skin tumor promotion and induction of apoptosis in HL-60 cells by Alpinia oxyphylla Miquel (Zingiberaceae).
Carcinogenesis 1998;19(8):1377-81.
1998: Park K K; Chun K S; Lee J M; Lee S S; Surh Y J
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.
Cancer letters 1998;129(2):139-44.
1998: Surh Y J; Kim S G; Park K K; Sohn Y; Lee J M; Kim N D; Miller J A
Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide.
Carcinogenesis 1998;19(7):1263-7.
1998: Surh Y J; Lee E; Lee J M
Chemoprotective properties of some pungent ingredients present in red pepper and ginger.
Mutation research 1998;402(1-2):259-67.
1998: Surh Y J
Bioactivation of benzylic and allylic alcohols via sulfo-conjugation.
Chemico-biological interactions 1998;109(1-3):221-35.
1997: Park K K; Surh Y J
Effects of capsaicin on chemically-induced two-stage mouse skin carcinogenesis.
Cancer letters 1997;114(1-2):183-4.
1996: Cho Y S; Kim B Y; Lee S T; Surh Y J; Chung A S
Chemopreventive effect of chlorophyllin on mutagenicity and cytotoxicity of 6-sulfooxymethylbenzo[a]pyrene.
Cancer letters 1996;107(2):223-8.
1996: Surh Y J; Shlyankevich M; Lee J W; Yoo J K
Inhibition of covalent DNA binding and mutagenicity of benzo[a]pyrene by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2-yl) carbamoyl]acetate (YH439), a novel hepatoprotective agent.
Mutation research 1996;367(4):219-24.
1996: Surh Y J
Sulfotransferase-mediated activation of some benzylic and allylic alcohols.
Advances in experimental medicine and biology 1996;387():339-45.
1995: Jeong H K; Shlyankevich M; Surh Y J
Intrinsic mutagenicity and electrophilicity of 1-sulfooxy-3-methylcholanthrene: implications for metabolic activation of the carcinogen 3-methylcholanthrene.
Biochemistry and molecular biology international 1995;37(5):885-93.
1995: Surh Y J; Lee R C; Park K K; Mayne S T; Liem A; Miller J A
Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine.
Carcinogenesis 1995;16(10):2467-71.
1995: Surh Y J; Park K K; Shlyankevich M
Inhibitory effects of chlorophyllin on chemically induced mutagenesis and carcinogenesis.
Annals of the New York Academy of Sciences 1995;768():246-9.
1995: Surh Y J; Tannenbaum S R
Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene.
Chemical research in toxicology 1995;8(5):693-8.
1995: Lee Y C; Shlyankevich M; Jeong H K; Douglas J S; Surh Y J
Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric acid ester.
Biochemical and biophysical research communications 1995;209(3):996-1002.
1995: Surh Y J; Ahn S H; Kim K C; Park J B; Sohn Y W; Lee S S
Metabolism of capsaicinoids: evidence for aliphatic hydroxylation and its pharmacological implications.
Life sciences 1995;56(16):PL305-11.
1995: Surh Y J; Lee S S
Capsaicin, a double-edged sword: toxicity, metabolism, and chemopreventive potential.
Life sciences 1995;56(22):1845-55.
1994: Surh Y J; Liem A; Miller J A; Tannenbaum S R
5-Sulfooxymethylfurfural as a possible ultimate mutagenic and carcinogenic metabolite of the Maillard reaction product, 5-hydroxymethylfurfural.
Carcinogenesis 1994;15(10):2375-7.
1994: Surh Y J; Miller J A
Roles of electrophilic sulfuric acid ester metabolites in mutagenesis and carcinogenesis by some polynuclear aromatic hydrocarbons.
Chemico-biological interactions 1994;92(1-3):351-62.
1994: Surh Y J; Lee S S
Enzymatic reduction of xenobiotic alpha,beta-unsaturated ketones: formation of allyl alcohol metabolites from shogaol and dehydroparadol.
Research communications in chemical pathology and pharmacology 1994;84(1):53-61.
1994: Surh Y J; Lee S S
Enzymic reduction of [6]-gingerol, a major pungent principle of ginger, in the cell-free preparation of rat liver.
Life sciences 1994;54(19):PL321-6.
1992: Surh Y J; Lee S S
Enzymatic reduction of shogaol: a novel biotransformation pathway for the alpha,beta-unsaturated ketone system.
Biochemistry international 1992;27(1):179-87.
1991: Surh Y J; Liem A; Miller E C; Miller J A
7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthracene.
Carcinogenesis 1991;12(2):339-47.
1991: Surh Y J; Liem A; Miller E C; Miller J A
Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity.
Biochemical pharmacology 1991;41(2):213-21.
1991: Surh Y J; Blomquist J C; Miller J A
Activation of 1-hydroxymethylpyrene to an electrophilic and mutagenic metabolite by rat hepatic sulfotransferase activity.
Advances in experimental medicine and biology 1991;283():383-91.
1991: Miller J A; Surh Y J; Liem A; Miller E C
Electrophilic sulfuric acid ester metabolites of hydroxy-methyl aromatic hydrocarbons as precursors of hepatic benzylic DNA adducts in vivo.
Advances in experimental medicine and biology 1991;283():555-67.
1990: Surh Y J; Liem A; Miller E C; Miller J A
The strong hepatocarcinogenicity of the electrophilic and mutagenic metabolite 6-sulfooxymethylbenzo[a]pyrene and its formation of benzylic DNA adducts in the livers of infant male B6C3F1 mice.
Biochemical and biophysical research communications 1990;172(1):85-91.
1990: Surh Y J; Blomquist J C; Liem A; Miller J A
Metabolic activation of 9-hydroxymethyl-10-methylanthracene and 1-hydroxymethylpyrene to electrophilic, mutagenic and tumorigenic sulfuric acid esters by rat hepatic sulfotransferase activity.
Carcinogenesis 1990;11(9):1451-60.
1989: Surh Y J; Liem A; Miller E C; Miller J A
Metabolic activation of the carcinogen 6-hydroxymethylbenzo[a]pyrene: formation of an electrophilic sulfuric acid ester and benzylic DNA adducts in rat liver in vivo and in reactions in vitro.
Carcinogenesis 1989;10(8):1519-28.

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