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Raj Suryanarayanan

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Chemistry, Pharmaceutical

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Publications

TOP 3
Sunny P Bhardwaj; Raj Suryanarayanan
Molecular mobility as a predictor of the water sorption by annealed amorphous trehalose.
Sunny P Bhardwaj; Sophie-Dorothee Clas; Elizabeth Kwong; Kapildev K Arora; Allen Templeton; Raj Suryanarayanan
Correlation between molecular mobility and physical stability of amorphous itraconazole.
Sunny P Bhardwaj; Raj Suryanarayanan
Molecular mobility as an effective predictor of the physical stability of amorphous trehalose.

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All Publications

2013: Sunny P Bhardwaj; Raj Suryanarayanan
Molecular mobility as a predictor of the water sorption by annealed amorphous trehalose.
Pharmaceutical research 2013;30(3):714-20.
2013: Sunny P Bhardwaj; Sophie-Dorothee Clas; Elizabeth Kwong; Kapildev K Arora; Allen Templeton; Raj Suryanarayanan
Correlation between molecular mobility and physical stability of amorphous itraconazole.
Molecular pharmaceutics 2013;10(2):694-700.
2012: Sunny P Bhardwaj; Raj Suryanarayanan
Molecular mobility as an effective predictor of the physical stability of amorphous trehalose.
Molecular pharmaceutics 2012;9(11):3209-17.
2012: Sunny P Bhardwaj; Raj Suryanarayanan
Use of dielectric spectroscopy to monitor molecular mobility in glassy and supercooled trehalose.
The journal of physical chemistry. B 2012;116(38):11728-36.
2012: Prakash Sundaramurthi; Michael R Burcusa; Raj Suryanarayanan
Physical characterization of pentamidine isethionate during freeze-drying-relevance to development of stable lyophilized product.
Journal of pharmaceutical sciences 2012;101(5):1732-43.
2012: Paroma Chakravarty; Raj Suryanarayanan; Ramprakash Govindarajan
Phase transformation in thiamine hydrochloride tablets: Influence on tablet microstructure, physical properties, and performance.
Journal of pharmaceutical sciences 2012;101(4):1410-22.
2012: Prakash Sundaramurthi; Raj Suryanarayanan
Calorimetry and complementary techniques to characterize frozen and freeze-dried systems.
Advanced drug delivery reviews 2012;64(5):384-95.
2011: Sisir Bhattacharya; Raj Suryanarayanan
Molecular motions in sucrose-PVP and sucrose-sorbitol dispersions: I. Implications of global and local mobility on stability.
Pharmaceutical research 2011;28(9):2191-203.
2011: Bakul S Bhatnagar; Tapan K Das; Tamara S Hodge; Liji Joseph; Susan W H Martin; Evgenyi Y Shalaev; Dirk L Teagarden; Raj Suryanarayanan
Investigation of PEG crystallization in frozen and freeze-dried PEGylated recombinant human growth hormone-sucrose systems: implications on storage stability.
Journal of pharmaceutical sciences 2011;100(8):3062-75.
2011: Kapildev K Arora; Nitin G Tayade; Raj Suryanarayanan
Unintended water mediated cocrystal formation in carbamazepine and aspirin tablets.
Molecular pharmaceutics 2011;8(3):982-9.
2011: Prakash Sundaramurthi; Raj Suryanarayanan
Thermophysical properties of carboxylic and amino acid buffers at subzero temperatures: relevance to frozen state stabilization.
The journal of physical chemistry. B 2011;115(21):7154-64.
2011: Prakash Sundaramurthi; Raj Suryanarayanan
The effect of crystallizing and non-crystallizing cosolutes on succinate buffer crystallization and the consequent pH shift in frozen solutions.
Pharmaceutical research 2011;28(2):374-85.
2010: Bakul S Bhatnagar; Susan M Martin; Dirk L Teagarden; Evgenyi Y Shalaev; Raj Suryanarayanan
Investigation of PEG crystallization in frozen PEG-sucrose-water solutions: II. Characterization of the equilibrium behavior during freeze-thawing.
Journal of pharmaceutical sciences 2010;99(11):4510-24.
2010: Prakash Sundaramurthi; Raj Suryanarayanan
Influence of crystallizing and non-crystallizing cosolutes on trehalose crystallization during freeze-drying.
Pharmaceutical research 2010;27(11):2384-93.
2010: Prakash Sundaramurthi; Thomas W Patapoff; Raj Suryanarayanan
Crystallization of trehalose in frozen solutions and its phase behavior during drying.
Pharmaceutical research 2010;27(11):2374-83.
2010: Paroma Chakravarty; Ramprakash Govindarajan; Raj Suryanarayanan
Investigation of solution and vapor phase mediated phase transformation in thiamine hydrochloride.
Journal of pharmaceutical sciences 2010;99(9):3941-52.
2010: Dabing Chen; Greg Haugstad; ZJ Li; Raj Suryanarayanan
Water sorption induced transformations in crystalline solid surfaces: characterization by atomic force microscopy.
Journal of pharmaceutical sciences 2010;99(9):4032-41.
2010: Bakul S Bhatnagar; Susan M Martin; Dirk L Teagarden; Evgenyi Y Shalaev; Raj Suryanarayanan
Investigation of PEG crystallization in frozen PEG-sucrose-water solutions. I. Characterization of the nonequilibrium behavior during freeze-thawing.
Journal of pharmaceutical sciences 2010;99(6):2609-19.
2010: Prakash Sundaramurthi; Evgenyi Y Shalaev; Raj Suryanarayanan
Calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions.
The journal of physical chemistry. B 2010;114(14):4915-23.
2010: Paroma Chakravarty; Robert T Berendt; Eric J Munson; Victor G Young; Ramprakash Govindarajan; Raj Suryanarayanan
Insights into the dehydration behavior of thiamine hydrochloride (vitamin B1) hydrates: part II.
Journal of pharmaceutical sciences 2010;99(4):1882-95.
2010: Hiroyuki Yamada; Katsuhide Terada; Raj Suryanarayanan
Non-destructive determination of the coating film thickness by X-ray powder diffractometry and correlation with the dissolution behavior of film-coated tablets.
Journal of pharmaceutical and biomedical analysis 2010;51(4):952-7.
2010: Paroma Chakravarty; Robert T Berendt; Eric J Munson; Victor G Young; Ramprakash Govindarajan; Raj Suryanarayanan
Insights into the dehydration behavior of thiamine hydrochloride (vitamin B1) hydrates: part I.
Journal of pharmaceutical sciences 2010;99(2):816-27.
2009: Enxian Lu; Susan Ewing; Larry A Gatlin; Raj Suryanarayanan; Evgenyi Y Shalaev
The effect of bulking agents on the chemical stability of acid-sensitive compounds in freeze-dried formulations: sucrose inversion study.
Journal of pharmaceutical sciences 2009;98(9):3387-96.
2009: Sisir Bhattacharya; Raj Suryanarayanan
Local mobility in amorphous pharmaceuticals--characterization and implications on stability.
Journal of pharmaceutical sciences 2009;98(9):2935-53.
2009: Dushyant B Varshney; Prakash Sundaramurthi; Satyendra Kumar; Evgenyi Y Shalaev; Shin-Woong Kang; Larry A Gatlin; Raj Suryanarayanan
Phase transitions in frozen systems and during freeze-drying: quantification using synchrotron X-ray diffractometry.
Pharmaceutical research 2009;26(7):1596-606.
2009: Ion Dranca; Sisir Bhattacharya; Sergey Vyazovkin; Raj Suryanarayanan
Implications of global and local mobility in amorphous sucrose and trehalose as determined by differential scanning calorimetry.
Pharmaceutical research 2009;26(5):1064-72.
2009: Tamaki Miyazaki; Kannan Sivaprakasam; Jaidev Tantry; Raj Suryanarayanan
Physical characterization of dibasic calcium phosphate dihydrate and anhydrate.
Journal of pharmaceutical sciences 2009;98(3):905-16.
2009: Paroma Chakravarty; Sunny P Bhardwaj; Leslie King; Raj Suryanarayanan
Monitoring phase transformations in intact tablets of trehalose by FT-Raman spectroscopy.
AAPS PharmSciTech 2009;10(4):1420-6.
2008: Koustuv Chatterjee; Evgenyi Y Shalaev; Raj Suryanarayanan; Ramprakash Govindarajan
Correlation between chemical reactivity and the Hammett acidity function in amorphous solids using inversion of sucrose as a model reaction.
Journal of pharmaceutical sciences 2008;97(1):274-86.
2007: Hiroyuki Yamada; Raj Suryanarayanan
X-ray powder diffractometry of intact film coated tablets--an approach to monitor the physical form of the active pharmaceutical ingredient during processing and storage.
Journal of pharmaceutical sciences 2007;96(8):2029-36.
2007: Jaidev S Tantry; Jitesh Tank; Raj Suryanarayanan
Processing-induced phase transitions of theophylline--implications on the dissolution of theophylline tablets.
Journal of pharmaceutical sciences 2007;96(5):1434-44.
2007: Dushyant B Varshney; Satyendra Kumar; Evgenyi Y Shalaev; Prakash Sundaramurthi; Shin-Woong Kang; Larry A Gatlin; Raj Suryanarayanan
Glycine crystallization in frozen and freeze-dried systems: effect of pH and buffer concentration.
Pharmaceutical research 2007;24(3):593-604.
2007: Xiangmin Liao; Rajesh Krishnamurthy; Raj Suryanarayanan
Influence of processing conditions on the physical state of mannitol--implications in freeze-drying.
Pharmaceutical research 2007;24(2):370-6.
2006: Cletus Nunes; Arumugam Mahendrasingam; Raj Suryanarayanan
Investigation of the multi-step dehydration reaction of theophylline monohydrate using 2-dimensional powder X-ray diffractometry.
Pharmaceutical research 2006;23(10):2393-404.
2006: Ramprakash Govindarajan; Andrey V Zinchuk; Bruno Hancock; Evgenyi Y Shalaev; Raj Suryanarayanan
Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing.
Pharmaceutical research 2006;23(10):2454-68.
2006: Dushyant B Varshney; Satyendra Kumar; Evgenyi Y Shalaev; Shin-Woong Kang; Larry A Gatlin; Raj Suryanarayanan
Solute crystallization in frozen systems-use of synchrotron radiation to improve sensitivity.
Pharmaceutical research 2006;23(10):2368-74.
2006: Meena Rani; Ramprakash Govindarajan; Rahul Surana; Raj Suryanarayanan
Structure in dehydrated trehalose dihydrate--evaluation of the concept of partial crystallinity.
Pharmaceutical research 2006;23(10):2356-67.
2006: Hiroyuki Yamada; Raj Suryanarayanan
Calculation of the penetration depth of X-rays in intact pharmaceutical film-coated tablets by microdiffractometry.
Pharmaceutical research 2006;23(9):2149-57.
2006: Ramprakash Govindarajan; Koustuv Chatterjee; Larry A Gatlin; Raj Suryanarayanan; Evgenyi Y Shalaev
Impact of freeze-drying on ionization of sulfonephthalein probe molecules in trehalose-citrate systems.
Journal of pharmaceutical sciences 2006;95(7):1498-510.
2005: Xiangmin Liao; Rajesh Krishnamurthy; Raj Suryanarayanan
Influence of the active pharmaceutical ingredient concentration on the physical state of mannitol--implications in freeze-drying.
Pharmaceutical research 2005;22(11):1978-85.
2005: Cletus Nunes; Arumugam Mahendrasingam; Raj Suryanarayanan
Quantification of crystallinity in substantially amorphous materials by synchrotron X-ray powder diffractometry.
Pharmaceutical research 2005;22(11):1942-53.
2005: Koustuv Chatterjee; Evgenyi Y Shalaev; Raj Suryanarayanan
Partially crystalline systems in lyophilization: I. Use of ternary state diagrams to determine extent of crystallization of bulking agent.
Journal of pharmaceutical sciences 2005;94(4):798-808.
2005: Koustuv Chatterjee; Evgenyi Y Shalaev; Raj Suryanarayanan
Partially crystalline systems in lyophilization: II. Withstanding collapse at high primary drying temperatures and impact on protein activity recovery.
Journal of pharmaceutical sciences 2005;94(4):809-20.
2005: Koustuv Chatterjee; Evgenyi Y Shalaev; Raj Suryanarayanan
Raffinose crystallization during freeze-drying and its impact on recovery of protein activity.
Pharmaceutical research 2005;22(2):303-9.
2005: Chitra Telang; Raj Suryanarayanan
Crystallization of cephalothin sodium during lyophilization from tert-butyl alcohol-water cosolvent system.
Pharmaceutical research 2005;22(1):153-60.
2004: Cletus Nunes; Raj Suryanarayanan; Cristian E Botez; Peter W Stephens
Characterization and crystal structure of D-mannitol hemihydrate.
Journal of pharmaceutical sciences 2004;93(11):2800-9.
2004: Shu Jun Bai; Meena Rani; Raj Suryanarayanan; John F Carpenter; Rajiv Nayar; Mark C Manning
Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy.
Journal of pharmaceutical sciences 2004;93(10):2439-47.
2004: Rahul Surana; Abira Pyne; Raj Suryanarayanan
Effect of preparation method on physical properties of amorphous trehalose.
Pharmaceutical research 2004;21(7):1167-76.
2004: Rahul Surana; Abira Pyne; Raj Suryanarayanan
Effect of aging on the physical properties of amorphous trehalose.
Pharmaceutical research 2004;21(5):867-74.
2004: Jeffrey D Meyer; Shu Jun Bai; Meena Rani; Raj Suryanarayanan; Rajiv Nayar; John F Carpenter; Mark C Manning
Infrared spectroscopic studies of protein formulations containing glycine.
Journal of pharmaceutical sciences 2004;93(5):1359-66.
2004: Smita Debnath; Raj Suryanarayanan
Influence of processing-induced phase transformations on the dissolution of theophylline tablets.
AAPS PharmSciTech 2004;5(1):E8.
2004: Smita Debnath; Paul Predecki; Raj Suryanarayanan
Use of glancing angle X-ray powder diffractometry to depth-profile phase transformations during dissolution of indomethacin and theophylline tablets.
Pharmaceutical research 2004;21(1):149-59.
2004: Cletus Nunes; Jun Han; Donald C Monkhouse; Raj Suryanarayanan
Preformulation studies to meet the challenges in the manufacture of betaine solid dosage form.
Journal of pharmaceutical sciences 2004;93(1):38-47.
2003: Rahul Surana; Abira Pyne; Raj Suryanarayanan
Solid-vapor interactions: influence of environmental conditions on the dehydration of carbamazepine dihydrate.
AAPS PharmSciTech 2003;4(4):E68.
2003: Chitra Telang; Raj Suryanarayanan; Lian Yu
Crystallization of D-mannitol in binary mixtures with NaCl: phase diagram and polymorphism.
Pharmaceutical research 2003;20(12):1939-45.
2003: Abira Pyne; Koustuv Chatterjee; Raj Suryanarayanan
Solute crystallization in mannitol-glycine systems--implications on protein stabilization in freeze-dried formulations.
Journal of pharmaceutical sciences 2003;92(11):2272-83.
2003: Rahul Surana; Linda Randall; Abira Pyne; N Murti Vemuri; Raj Suryanarayanan
Determination of glass transition temperature and in situ study of the plasticizing effect of water by inverse gas chromatography.
Pharmaceutical research 2003;20(10):1647-54.
2003: Geoff G Z Zhang; Sophia Y L Paspal; Raj Suryanarayanan; David J W Grant
Racemic species of sodium ibuprofen: characterization and polymorphic relationships.
Journal of pharmaceutical sciences 2003;92(7):1356-66.
2003: Abira Pyne; Koustuv Chatterjee; Raj Suryanarayanan
Crystalline to amorphous transition of disodium hydrogen phosphate during primary drying.
Pharmaceutical research 2003;20(5):802-3.
2003: Chitra Telang; Lian Yu; Raj Suryanarayanan
Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride.
Pharmaceutical research 2003;20(4):660-7.
2003: Abira Pyne; Raj Suryanarayanan
The effect of additives on the crystallization of cefazolin sodium during freeze-drying.
Pharmaceutical research 2003;20(2):283-91.
2002: Suneel K Rastogi; Marek Zakrzewski; Raj Suryanarayanan
Investigation of solid-state reactions using variable temperature X-ray powder diffractometry. II. Aminophylline monohydrate.
Pharmaceutical research 2002;19(9):1265-73.
2002: Abira Pyne; Rahul Surana; Raj Suryanarayanan
Crystallization of mannitol below Tg' during freeze-drying in binary and ternary aqueous systems.
Pharmaceutical research 2002;19(6):901-8.
2002: Raghu K Cavatur; N Murti Vemuri; Abira Pyne; Zofia Chrzan; David Toledo-Velasquez; Raj Suryanarayanan
Crystallization behavior of mannitol in frozen aqueous solutions.
Pharmaceutical research 2002;19(6):894-900.
2002: Alekha K Dash; A Khin-Khin; Raj Suryanarayanan
X-ray powder diffractometric method for quantitation of crystalline drug in microparticulate systems. I. Microspheres.
Journal of pharmaceutical sciences 2002;91(4):983-90.
2001: Abira Pyne; Raj Suryanarayanan
Phase transitions of glycine in frozen aqueous solutions and during freeze-drying.
Pharmaceutical research 2001;18(10):1448-54.
2001: S Rastogi; M Zakrzewski; Raj Suryanarayanan
Investigation of solid-state reactions using variable temperature X-ray powder diffractrometry. I. Aspartame hemihydrate.
Pharmaceutical research 2001;18(3):267-73.
2000: Y Li; J Han; Geoff G Z Zhang; David J W Grant; Raj Suryanarayanan
In situ dehydration of carbamazepine dihydrate: a novel technique to prepare amorphous anhydrous carbamazepine.
Pharmaceutical development and technology 2000;5(2):257-66.
1999: S Rastogi; I Zamansky; S Roy; P Tyle; Raj Suryanarayanan
Solid-state phase transitions of AG337, an antitumor agent.
Pharmaceutical development and technology 1999;4(4):623-32.
1998: J Han; Raj Suryanarayanan
Influence of environmental conditions on the kinetics and mechanism of dehydration of carbamazepine dihydrate.
Pharmaceutical development and technology 1998;3(4):587-96.
1998: Raghu K Cavatur; Raj Suryanarayanan
Characterization of phase transitions during freeze-drying by in situ X-ray powder diffractometry.
Pharmaceutical development and technology 1998;3(4):579-86.
1998: Raghu K Cavatur; Raj Suryanarayanan
Characterization of frozen aqueous solutions by low temperature X-ray powder diffractometry.
Pharmaceutical research 1998;15(2):194-9.
1997: NV Phadnis; Raj Suryanarayanan
Polymorphism in anhydrous theophylline--implications on the dissolution rate of theophylline tablets.
Journal of pharmaceutical sciences 1997;86(11):1256-63.
1997: NV Phadnis; Raj Suryanarayanan
Simultaneous quantification of an enantiomer and the racemic compound of ibuprofen by X-ray powder diffractometry.
Pharmaceutical research 1997;14(9):1176-80.
1997: NV Phadnis; Raghu K Cavatur; Raj Suryanarayanan
Identification of drugs in pharmaceutical dosage forms by X-ray powder diffractometry.
Journal of pharmaceutical and biomedical analysis 1997;15(7):929-43.
1997: S P Duddu; A Khin-Khin; David J W Grant; Raj Suryanarayanan
A novel X-ray powder diffractometric method for studying the reaction between pseudoephedrine enantiomers.
Journal of pharmaceutical sciences 1997;86(3):340-5.
1992: A K Dash; Raj Suryanarayanan
An implantable dosage form for the treatment of bone infections.
Pharmaceutical research 1992;9(8):993-1002.
1991: W W Young; Raj Suryanarayanan
Kinetics of transition of anhydrous carbamazepine to carbamazepine dihydrate in aqueous suspensions.
Journal of pharmaceutical sciences 1991;80(5):496-500.
1991: Raj Suryanarayanan; C S Herman
Quantitative analysis of the active tablet ingredient by powder X-ray diffractometry.
Pharmaceutical research 1991;8(3):393-9.
1991: A K Dash; Raj Suryanarayanan
A liquid-chromatographic method for the determination of tobramycin.
Journal of pharmaceutical and biomedical analysis 1991;9(3):237-45.
1990: Raj Suryanarayanan; Timothy Scott Wiedmann
Quantitation of the relative amounts of anhydrous carbamazepine (C15H12N2O) and carbamazepine dihydrate (C15H12N2O.2H2O) in a mixture by solid-state nuclear magnetic resonance (NMR).
Pharmaceutical research 1990;7(2):184-7.
1989: Raj Suryanarayanan
Determination of the relative amounts of anhydrous carbamazepine (C15H12N2O) and carbamazepine dihydrate (C15H12N2O.2H2O) in a mixture by powder x-ray diffractometry.
Pharmaceutical research 1989;6(12):1017-24.