FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Santos Susin

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Phenomena

Permeability

Concepts & Ideas

Membrane Potentials

Physiology

Co-author Network

Publications

TOP 3
Vu Quang Van; Keiko Wakahara; Santos A Susin; Nobuyasu Baba; Marianne Raymond; Manuel Rubio; Marika Sarfati
CD47(high) expression on CD4 effectors identifies functional long-lived memory T cell progenitors.
Laure Delavallée; Lauriane Cabon; Patricia Galán-Malo; Hans K Lorenzo; Santos A Susin
AIF-mediated caspase-independent necroptosis: a new chance for targeted therapeutics.
Mathieu Baritaud; Hanan Boujrad; Hans K Lorenzo; Slavica Krantic; Santos A Susin
Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Santos Susin (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Vu Quang Van; Keiko Wakahara; Santos A Susin; Nobuyasu Baba; Marianne Raymond; Manuel Rubio; Marika Sarfati
CD47(high) expression on CD4 effectors identifies functional long-lived memory T cell progenitors.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(9):4249-55.
2011: Laure Delavallée; Lauriane Cabon; Patricia Galán-Malo; Hans K Lorenzo; Santos A Susin
AIF-mediated caspase-independent necroptosis: a new chance for targeted therapeutics.
IUBMB life 2011;63(4):221-32.
2010: Mathieu Baritaud; Hanan Boujrad; Hans K Lorenzo; Slavica Krantic; Santos A Susin
Histone H2AX: The missing link in AIF-mediated caspase-independent programmed necrosis.
Cell cycle (Georgetown, Tex.) 2010;9(16):3166-73.
2010: Cédric Artus; Hanan Boujrad; Aïda Bouharrour; Marie-Noëlle Brunelle; Sylviane Hoos; Victor Jose Yuste; Pascal Lenormand; Jean-Claude Rousselle; Abdelkader Namane; Patrick England; Hans K Lorenzo; Santos A Susin
AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX.
The EMBO journal 2010;29(9):1585-99.
2009: Sandrine Barbier; Laurent Arnaud CHATRE; Marlène Bras; Patricia Sancho; Gaël Roué; Clémence Virely; Victor Jose Yuste; Sylvie Baudet; Manuel Rubio; Josep E Esquerda; Marika Sarfati; Hélène Merle-Béral; Santos A Susin
Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton.
Haematologica 2009;94(4):507-17.
2008: Séverine Derbré; Sophie Gil; Myriam Taverna; Céline Boursier; Valérie Nicolas; Emmanuelle Demey-Thomas; Joëlle Vinh; Santos A Susin; Reynald Hocquemiller; Erwan Poupon
Highly cytotoxic and neurotoxic acetogenins of the Annonaceae: new putative biological targets of squamocin detected by activity-based protein profiling.
Bioorganic & medicinal chemistry letters 2008;18(21):5741-4.
2007: Hans Lorenzo; Santos A Susin
Therapeutic potential of AIF-mediated caspase-independent programmed cell death.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2007;10(6):235-55.
2007: Hanan Boujrad; Olena Gubkina; Nadine Robert; Slavica Krantic; Santos A Susin
AIF-mediated programmed necrosis: a highly regulated way to die.
Cell cycle (Georgetown, Tex.) 2007;6(21):2612-9.
2007: Marlène Bras; Victor Jose Yuste; Gaël Roué; Sandrine Barbier; Patricia Sancho; Clémence Virely; Manuel Rubio; Sylvie Baudet; Josep Esquerda; Hélène Merle-Béral; Marika Sarfati; Santos A Susin
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells.
Molecular and cellular biology 2007;27(20):7073-88.
2007: Rana S Moubarak; Victor Jose Yuste; Cédric Artus; Aïda Bouharrour; Peter A Greer; Josiane Menissier-de Murcia; Santos A Susin
Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.
Molecular and cellular biology 2007;27(13):4844-62.
2007: stephanie Reix; Naguib Mechawar; Santos A Susin; Rémi Quirion; Slavica Krantic
Expression of cortical and hippocampal apoptosis-inducing factor (AIF) in aging and Alzheimer's disease.
Neurobiology of aging 2007;28(3):351-6.
2006: Cédric Artus; Eliane Maquarre; Rana S Moubarak; Cécile Delettre; Claude Jasmin; Santos A Susin; J Robert-Lézénès
CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells.
Oncogene 2006;25(42):5741-51.
2006: Cécile Delettre; Victor Jose Yuste; Rana S Moubarak; Marlène Bras; Nadine Robert; Santos A Susin
Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity.
The Journal of biological chemistry 2006;281(27):18507-18.
2006: Patricia Sancho; Carlos Fernandez; Victor Jose Yuste; Donna Amrán; Adrián M Ramos; Elena De Blas; Santos A Susin; Patricio Aller
Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress.
Apoptosis : an international journal on programmed cell death 2006;11(5):673-86.
2006: Julien Guergnon; Frédéric Dessauge; victoria dominguez; Jean Viallet; Serge Bonnefoy; Victor Jose Yuste; Odile Mercereau-Puijalon; Xavier Cayla; Angelita Rebollo; Santos A Susin; Pierre-Etienne Bost; Alphonse Garcia
Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology.
Molecular pharmacology 2006;69(4):1115-24.
2006: Cécile Delettre; Victor Jose Yuste; Rana S Moubarak; Marlène Bras; Jeanne-Claire Lesbordes-Brion; Stéphane Petres; Jacques Bellalou; Santos A Susin
AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer.
The Journal of biological chemistry 2006;281(10):6413-27.
2006: Séverine Derbré; Romain A Duval; Gaël Roué; Aurelio Garofano; Erwan Poupon; Ulrich Brandt; Santos A Susin; Reynald Hocquemiller
Semisynthesis and screening of a small library of pro-apoptotic squamocin analogues: selection and study of a benzoquinone hybrid with an improved biological profile.
ChemMedChem 2006;1(1):118-29.
2005: Victor Jose Yuste; Rana S Moubarak; Cécile Delettre; Marlène Bras; Patricia Sancho; Nadine Robert; J d'Alayer; Santos A Susin
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release.
Cell death and differentiation 2005;12(11):1445-8.
2005: Victor Jose Yuste; Isabel Sánchez-López; Carme Solé; Rana S Moubarak; Jose Ramon Bayascas; Xavier Dolcet; Mario Encinas; Santos A Susin; Joan X Comella
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis.
The Journal of biological chemistry 2005;280(42):35670-83.
2005: Séverine Derbré; Gaël Roué; Erwan Poupon; Santos A Susin; Reynald Hocquemiller
Annonaceous acetogenins: the hydroxyl groups and THF rings are crucial structural elements for targeting the mitochondria, demonstration with the synthesis of fluorescent squamocin analogues.
Chembiochem : a European journal of chemical biology 2005;6(6):979-82.
2005: Marlène Bras; B Queenan; Santos A Susin
Programmed cell death via mitochondria: different modes of dying.
Biochemistry. Biokhimii͡a 2005;70(2):231-9.
2004: Elisabetta Dondi; Gaël Roué; Victor Jose Yuste; Santos A Susin; Sandra Pellegrini
A dual role of IFN-alpha in the balance between proliferation and death of human CD4+ T lymphocytes during primary response.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3740-7.
2004: Hans Lorenzo; Santos A Susin
Mitochondrial effectors in caspase-independent cell death.
FEBS letters 2004;557(1-3):14-20.
2003: Maria-Isabel Thoulouze; Mireille Lafage; Victor Jose Yuste; Guido Kroemer; Santos A Susin; Nicole Israel; Monique Lafon
Apoptosis inversely correlates with rabies virus neurotropism.
Annals of the New York Academy of Sciences 2003;1010():598-603.
2003: Maria-Isabel Thoulouze; Mireille Lafage; Victor Jose Yuste; Leïla Baloul; Léna Edelman; Guido Kroemer; Nicole Israel; Santos A Susin; Monique Lafon
High level of Bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection.
Virology 2003;314(2):549-61.
2003: Adeline Catteau; Gaël Roué; Victor Jose Yuste; Santos A Susin; Philippe Desprès
Expression of dengue ApoptoM sequence results in disruption of mitochondrial potential and caspase activation.
Biochimie 2003;85(8):789-93.
2003: Gaël Roué; Natacha Bitton; Victor Jose Yuste; Thomas Montange; Manuel Rubio; Frédéric Dessauge; Cécile Delettre; Hélène Merle-Béral; Marika Sarfati; Santos A Susin
Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release.
Biochimie 2003;85(8):741-6.
2003: Toshio Hisatomi; Taiji Sakamoto; Koh-Hei Sonoda; Chikako Tsutsumi; Hong Qiao; Hiroshi Enaida; Ichiro Yamanaka; Toshiaki Kubota; Tatsuro Ishibashi; Shinobu Kura; Santos A Susin; Guido Kroemer
Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3.
The American journal of pathology 2003;162(6):1869-79.
2002: María J Maté; Miguel Ortiz-Lombardía; Brigitte Boitel; Ahmed Haouz; Diana Tello; Santos A Susin; Josef M Penninger; Guido Kroemer; Pedro Alzari
The crystal structure of the mouse apoptosis-inducing factor AIF.
Nature structural biology 2002;9(6):442-6.
2002: Toshio Hisatomi; Taiji Sakamoto; Yoshinobu Goto; Ichiro Yamanaka; Yuji Oshima; Yasuaki Hata; Tatsuro Ishibashi; Hajime Inomata; Santos A Susin; Guido Kroemer
Critical role of photoreceptor apoptosis in functional damage after retinal detachment.
Current eye research 2002;24(3):161-72.
2002: P Costantini; Jean-Marie Bruey; Maria Castedo; Didier Métivier; M Loeffler; Santos A Susin; Luigi Ravagnan; Naoufal Zamzami; Carmen Garrido; Guido Kroemer
Pre-processed caspase-9 contained in mitochondria participates in apoptosis.
Cell death and differentiation 2002;9(1):82-8.
2001: Luigi Ravagnan; Sandeep Gurbuxani; Santos A Susin; Carine Maisse; Eric Daugas; Naoufal Zamzami; T Mak; Marja Jäättelä; Josef M Penninger; Carmen Garrido; Guido Kroemer
Heat-shock protein 70 antagonizes apoptosis-inducing factor.
Nature cell biology 2001;3(9):839-43.
2001: M D Miramar; P Costantini; Luigi Ravagnan; Lígia M Saraiva; D Haouzi; Greg M Brothers; Josef M Penninger; M Luisa Peleato; Guido Kroemer; Santos A Susin
NADH oxidase activity of mitochondrial apoptosis-inducing factor.
The Journal of biological chemistry 2001;276(19):16391-8.
2001: Toshio Hisatomi; Taiji Sakamoto; Toshinori Murata; Ichiro Yamanaka; Yuji Oshima; Yasuaki Hata; Tatsuro Ishibashi; Hajime Inomata; Santos A Susin; Guido Kroemer
Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo.
The American journal of pathology 2001;158(4):1271-8.
2001: Nicholas Joza; Santos A Susin; Eric Daugas; William L Stanford; S K Cho; C Y Li; Takehiko Sasaki; Andrew Elia; Hai-Ying M Cheng; Luigi Ravagnan; Karine F Ferri; Naoufal Zamzami; Andrew Wakeham; Raza Hakem; H Yoshida; Young-Yun Kong; Tak W Mak; J C Zúñiga-Pflücker; Guido Kroemer; Josef M Penninger
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Nature 2001;410(6828):549-54.
2001: M Loeffler; Eric Daugas; Santos A Susin; Naoufal Zamzami; Didier Metivier; Anna-Liisa Nieminen; Greg M Brothers; Josef M Penninger; Guido Kroemer
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(3):758-67.
2000: Karine F Ferri; Etienne Jacotot; Julià Blanco; José A Esté; Naoufal Zamzami; Santos A Susin; Z Xie; Greg M Brothers; JC Reed; Josef M Penninger; Guido Kroemer
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.
The Journal of experimental medicine 2000;192(8):1081-92.
2000: Maria Rita Rippo; Florence Malisan; Luigi Ravagnan; Barbara Tomassini; Ivano Condo; P Costantini; Santos A Susin; Alessandra Rufini; Matilde Todaro; Guido Kroemer; Roberto Testi
GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2047-54.
2000: Maria Rita Rippo; Florence Malisan; Luigi Ravagnan; Barbara Tomassini; Ivano Condò; P Costantini; Santos A Susin; Alessandra Rufini; Matilde Todaro; Guido Kroemer; Roberto Testi
GD3 ganglioside as an intracellular mediator of apoptosis.
European cytokine network 2000;11(3):487-8.
2000: Jean-Marie Bruey; Cécile Ducasse; Philippe Bonniaud; Luigi Ravagnan; Santos A Susin; Chantal Diaz-Latoud; Sandeep Gurbuxani; André-Patrick Arrigo; Guido Kroemer; Eric Solary; Carmen Garrido
Hsp27 negatively regulates cell death by interacting with cytochrome c.
Nature cell biology 2000;2(9):645-52.
2000: Santos A Susin; Eric Daugas; Luigi Ravagnan; K Samejima; Naoufal Zamzami; M Loeffler; P Costantini; Karine F Ferri; T Irinopoulou; Marie-Christine Prévost; Greg M Brothers; Tak W Mak; Josef M Penninger; W C Earnshaw; Guido Kroemer
Two distinct pathways leading to nuclear apoptosis.
The Journal of experimental medicine 2000;192(4):571-80.
2000: Céline Dumont; Antoine Dürrbach; Nicolas Bidère; Matthieu Rouleau; G Kroemer; G Bernard; François Hirsch; Bernard Charpentier; Santos A Susin; Anna Senik
Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult.
Blood 2000;96(3):1030-8.
2000: Eric Daugas; Dominique Nochy; Luigi Ravagnan; M Loeffler; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis.
FEBS letters 2000;476(3):118-23.
2000: Chris Spahr; Santos A Susin; EJ Bures; JH Robinson; Michael T Davis; MD McGinley; Guido Kroemer; Scott D Patterson
Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides.
Electrophoresis 2000;21(9):1635-50.
2000: Eric Daugas; Santos A Susin; Naoufal Zamzami; Karine F Ferri; T Irinopoulou; Nathanael Larochette; Marie-Christine Prévost; Brian Leber; D Andrews; Josef M Penninger; Guido Kroemer
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):729-39.
2000: Scott D Patterson; Chris Spahr; Eric Daugas; Santos A Susin; T Irinopoulou; C Koehler; Guido Kroemer
Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition.
Cell death and differentiation 2000;7(2):137-44.
2000: P Costantini; Anne-Sophie Belzacq; Helena L A Vieira; Nathanael Larochette; MA de Pablo; Naoufal Zamzami; Santos A Susin; catherine brenner; Guido Kroemer
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis.
Oncogene 2000;19(2):307-14.
2000: Etienne Jacotot; Luigi Ravagnan; M Loeffler; Karine F Ferri; Helena L A Vieira; Naoufal Zamzami; P Costantini; Sabine Druillennec; J Hoebeke; Jean-Paul Briand; T Irinopoulou; Eric Daugas; Santos A Susin; D Cointe; ZH Xie; JC Reed; Bernard P Roques; Guido Kroemer
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
The Journal of experimental medicine 2000;191(1):33-46.
2000: Santos A Susin; Nathanael Larochette; M Geuskens; Guido Kroemer
Purification of mitochondria for apoptosis assays.
Methods in enzymology 2000;322():205-8.
2000: Hans Lorenzo; Santos A Susin; Guido Kroemer
Cytofluorometric quantitation of nuclear apoptosis induced in a cell-free system.
Methods in enzymology 2000;322():198-201.
1999: Philippe MARCHETTI; Naoufal Zamzami; Bertrand Joseph; Susanna Schraen-Maschke; Claude Méreau-Richard; P Costantini; Didier Métivier; Santos A Susin; Guido Kroemer; Pierre Formstecher
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.
Cancer research 1999;59(24):6257-66.
1999: Nathanael Larochette; Didier Decaudin; Etienne Jacotot; catherine brenner; I Marzo; Santos A Susin; Naoufal Zamzami; Z Xie; J Reed; Guido Kroemer
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Experimental cell research 1999;249(2):413-21.
1999: Hans Lorenzo; Santos A Susin; Josef M Penninger; Guido Kroemer
Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death.
Cell death and differentiation 1999;6(6):516-24.
1999: Luigi Ravagnan; I Marzo; P Costantini; Santos A Susin; Naoufal Zamzami; Patrice X. PETIT; François Hirsch; M Goulbern; Marie-France Poupon; Laurent Miccoli; Z Xie; JC Reed; Guido Kroemer
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore.
Oncogene 1999;18(16):2537-46.
1999: MA de Pablo; Santos A Susin; Etienne Jacotot; Nathanael Larochette; P Costantini; Luigi Ravagnan; Naoufal Zamzami; Guido Kroemer
Palmitate induces apoptosis via a direct effect on mitochondria.
Apoptosis : an international journal on programmed cell death 1999;4(2):81-7.
1999: Santos A Susin; Hans Lorenzo; Naoufal Zamzami; I Marzo; B E Snow; Greg M Brothers; J Mangion; Etienne Jacotot; P Costantini; M Loeffler; Nathanael Larochette; D R Goodlett; R Aebersold; David Siderovski; Josef M Penninger; Guido Kroemer
Molecular characterization of mitochondrial apoptosis-inducing factor.
Nature 1999;397(6718):441-6.
1999: Santos A Susin; Hans Lorenzo; Naoufal Zamzami; I Marzo; catherine brenner; Nathanael Larochette; Marie-Christine Prévost; Pedro Alzari; Guido Kroemer
Mitochondrial release of caspase-2 and -9 during the apoptotic process.
The Journal of experimental medicine 1999;189(2):381-94.
1999: Etienne Jacotot; P Costantini; E Laboureau; Naoufal Zamzami; Santos A Susin; Guido Kroemer
Mitochondrial membrane permeabilization during the apoptotic process.
Annals of the New York Academy of Sciences 1999;887():18-30.
1998: I Marzo; catherine brenner; Naoufal Zamzami; J M Jürgensmeier; Santos A Susin; Helena L A Vieira; Marie-Christine Prévost; Z Xie; S Matsuyama; J C Reed; G Kroemer
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis.
Science (New York, N.Y.) 1998;281(5385):2027-31.
1998: T Hirsch; B Dallaporta; Naoufal Zamzami; Santos A Susin; Luigi Ravagnan; I Marzo; catherine brenner; Guido Kroemer
Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):35-40.
1998: T Hirsch; Didier Decaudin; Santos A Susin; Philippe MARCHETTI; Nathanael Larochette; M Resche-Rigon; Guido Kroemer
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.
Experimental cell research 1998;241(2):426-34.
1998: B Dallaporta; T Hirsch; Santos A Susin; Naoufal Zamzami; Nathanael Larochette; catherine brenner; I Marzo; Guido Kroemer
Potassium leakage during the apoptotic degradation phase.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5605-15.
1998: I Marzo; Santos A Susin; Patrice X. PETIT; Luigi Ravagnan; catherine brenner; Nathanael Larochette; Naoufal Zamzami; Guido Kroemer
Caspases disrupt mitochondrial membrane barrier function.
FEBS letters 1998;427(2):198-202.
1998: Naoufal Zamzami; catherine brenner; I Marzo; Santos A Susin; Guido Kroemer
Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins.
Oncogene 1998;16(17):2265-82.
1998: I Marzo; catherine brenner; Naoufal Zamzami; Santos A Susin; G Beutner; Dieter Brdiczka; R Rémy; ZH Xie; JC Reed; Guido Kroemer
The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins.
The Journal of experimental medicine 1998;187(8):1261-71.
1998: Patrice X. PETIT; Marc Goubern; Philippe Diolez; Santos A Susin; Naoufal Zamzami; G Kroemer
Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition.
FEBS letters 1998;426(1):111-6.
1998: Didier Métivier; B Dallaporta; Naoufal Zamzami; Nathanael Larochette; Santos A Susin; I Marzo; Guido Kroemer
Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes.
Immunology letters 1998;61(2-3):157-63.
1998: T Hirsch; Santos A Susin; I Marzo; Philippe MARCHETTI; Naoufal Zamzami; Guido Kroemer
Mitochondrial permeability transition in apoptosis and necrosis.
Cell biology and toxicology 1998;14(2):141-5.
1998: Naoufal Zamzami; I Marzo; Santos A Susin; catherine brenner; Nathanael Larochette; Philippe MARCHETTI; J Reed; Reinhard Kofler; Guido Kroemer
The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition.
Oncogene 1998;16(8):1055-63.
1997: Santos A Susin; Naoufal Zamzami; Nathanael Larochette; B Dallaporta; I Marzo; catherine brenner; T Hirsch; Patrice X. PETIT; M Geuskens; Guido Kroemer
A cytofluorometric assay of nuclear apoptosis induced in a cell-free system: application to ceramide-induced apoptosis.
Experimental cell research 1997;236(2):397-403.
1997: T Hirsch; Philippe MARCHETTI; Santos A Susin; B Dallaporta; Naoufal Zamzami; I Marzo; M Geuskens; Guido Kroemer
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.
Oncogene 1997;15(13):1573-81.
1997: Santos A Susin; Naoufal Zamzami; Maria Castedo; Eric Daugas; Hong-Gang Wang; Stephan Geley; F Fassy; J C Reed; Guido Kroemer
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.
The Journal of experimental medicine 1997;186(1):25-37.
1997: S Hortelano; B Dallaporta; Naoufal Zamzami; T Hirsch; Santos A Susin; I Marzo; L Boscá; Guido Kroemer
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.
FEBS letters 1997;410(2-3):373-7.
1997: Antonio Macho; T Hirsch; I Marzo; Philippe MARCHETTI; B Dallaporta; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4612-9.
1997: Philippe MARCHETTI; Didier Decaudin; Antonio Macho; Naoufal Zamzami; T Hirsch; Santos A Susin; Guido Kroemer
Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.
European journal of immunology 1997;27(1):289-96.
1997: G Kroemer; Naoufal Zamzami; Santos A Susin
Mitochondrial control of apoptosis.
Immunology today 1997;18(1):44-51.
1996: Antonio Macho; Didier Decaudin; Maria Castedo; T Hirsch; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.
Cytometry 1996;25(4):333-40.
1996: Philippe MARCHETTI; T Hirsch; Naoufal Zamzami; Maria Castedo; Didier Decaudin; Santos A Susin; B Masse; Guido Kroemer
Mitochondrial permeability transition triggers lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4830-6.
1996: Patrice X. PETIT; Santos A Susin; Naoufal Zamzami; Bernard Mignotte; Guido Kroemer
Mitochondria and programmed cell death: back to the future.
FEBS letters 1996;396(1):7-13.
1996: Santos A Susin; Naoufal Zamzami; Maria Castedo; T Hirsch; Philippe MARCHETTI; Antonio Macho; E Daugas; M Geuskens; Guido Kroemer
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
The Journal of experimental medicine 1996;184(4):1331-41.
1996: Philippe MARCHETTI; Maria Castedo; Santos A Susin; Naoufal Zamzami; T Hirsch; Antonio Macho; A Haeffner; François Hirsch; M Geuskens; Guido Kroemer
Mitochondrial permeability transition is a central coordinating event of apoptosis.
The Journal of experimental medicine 1996;184(3):1155-60.
1996: Maria Castedo; T Hirsch; Santos A Susin; Naoufal Zamzami; Philippe MARCHETTI; Antonio Macho; Guido Kroemer
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):512-21.
1996: Philippe MARCHETTI; Santos A Susin; Didier Decaudin; Susana Gamen; Maria Castedo; T Hirsch; Naoufal Zamzami; Javier Naval; A Senik; Guido Kroemer
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.
Cancer research 1996;56(9):2033-8.
1996: Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo; T Hirsch; Santos A Susin; B Masse; Guido Kroemer
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.
FEBS letters 1996;384(1):53-7.
1996: Naoufal Zamzami; Santos A Susin; Philippe MARCHETTI; T Hirsch; I Gómez-Monterrey; Maria Castedo; Guido Kroemer
Mitochondrial control of nuclear apoptosis.
The Journal of experimental medicine 1996;183(4):1533-44.
1996: Georges Rawadi; Sergio Roman-Roman; Maria Castedo; V Dutilleul; Santos A Susin; Philippe MARCHETTI; M Geuskens; Guido Kroemer
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):670-8.
1995: Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo; Didier Decaudin; Antonio Macho; T Hirsch; Santos A Susin; Patrice X. PETIT; Bernard Mignotte; Guido Kroemer
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
The Journal of experimental medicine 1995;182(2):367-77.