FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brian Sutton

Research Profile

Chemicals & Drugs

Concepts & Ideas

Phenomena

Disorders

Hypersensitivity

Anatomy

B-Lymphocytes

Living Beings

Mouse

Co-author Network

Publications

TOP 3
Anna M Davies; Tamara H den Bleker; Hannah J Gould; James M McDonnell; Theo Rispens; Rob C Aalberse; Brian J Sutton
Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange.
Susmita Borthakur; Alison M Cooper; Hannah J Gould; Richard G Hibbert; Michael W Kao; Heather J Bax; Andrew J Beavil; Marie O Y Pang; Brian J Sutton; Norhakim Yahya; James M McDonnell
Mapping of the CD23 binding site on immunoglobulin E (IgE) and allosteric control of the IgE-Fc epsilonRI interaction.
Balvinder Dhaliwal; Stella M Fabiane; Hannah J Gould; Alistair J Henry; James M McDonnell; Amanda Oxbrow; Marie O Y Pang; Andrew John Beavil; Katharine Cain; Daopeng Yuan; Brian J Sutton
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brian Sutton (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Anna M Davies; Tamara H den Bleker; Hannah J Gould; James M McDonnell; Theo Rispens; Rob C Aalberse; Brian J Sutton
Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange.
Molecular immunology 2013;54(1):1-7.
2012: Susmita Borthakur; Alison M Cooper; Hannah J Gould; Richard G Hibbert; Michael W Kao; Heather J Bax; Andrew J Beavil; Marie O Y Pang; Brian J Sutton; Norhakim Yahya; James M McDonnell
Mapping of the CD23 binding site on immunoglobulin E (IgE) and allosteric control of the IgE-Fc epsilonRI interaction.
The Journal of biological chemistry 2012;287(37):31457-61.
2012: Balvinder Dhaliwal; Stella M Fabiane; Hannah J Gould; Alistair J Henry; James M McDonnell; Amanda Oxbrow; Marie O Y Pang; Andrew John Beavil; Katharine Cain; Daopeng Yuan; Brian J Sutton
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(31):12686-91.
2012: James Hunt; Anthony H Keeble; James Levitt; Klaus Suhling; Brian J Sutton; Marcus J Swann; Simon Ameer-Beg; Rebecca L Beavil; Melissa K Corbett; Robert E Dale; Andrew J Beavil
A fluorescent biosensor reveals conformational changes in human immunoglobulin E Fc: implications for mechanisms of receptor binding, inhibition, and allergen recognition.
The Journal of biological chemistry 2012;287(21):17459-70.
2012: Alison M Cooper; Binia Drung; David J Fear; Philip S Hobson; Mark R Jutton; Michael W Kao; James M McDonnell; Boris Schmidt; Brian J Sutton; Andrew John Beavil; Hannah J Gould
Soluble CD23 controls IgE synthesis and homeostasis in human B cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):3199-207.
2011: Mary D Holdom; Anna M Davies; Joanne E Nettleship; Sarah C Bagby; Balvinder Dhaliwal; Enrico Girardi; James Hunt; Hannah J Gould; Andrew John Beavil; James M McDonnell; Ray J Owens; Brian J Sutton
Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI.
Nature structural & molecular biology 2011;18(5):571-6.
2010: Alexander Taylor; Brian J Sutton; Rosaleen A Calvert
Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites.
Developmental and comparative immunology 2010;34(2):97-101.
2009: Alexander Taylor; Rebecca L Beavil; Brian J Sutton; Rosaleen A Calvert
A monomeric chicken IgY receptor binds IgY with 2:1 stoichiometry.
The Journal of biological chemistry 2009;284(36):24168-75.
2009: Anna M Davies; Renée Tata; Alison Snape; Brian J Sutton; Paul R Brown
Structure and substrate specificity of acetyltransferase ACIAD1637 from Acinetobacter baylyi ADP1.
Biochimie 2009;91(4):484-9.
2009: Alexander Taylor; Stella M Fabiane; Brian J Sutton; Rosaleen A Calvert
The crystal structure of an avian IgY-Fc fragment reveals conservation with both mammalian IgG and IgE.
Biochemistry 2009;48(3):558-62.
2009: Enrico Girardi; Mary D Holdom; Anna M Davies; Brian J Sutton; Andrew John Beavil
The crystal structure of rabbit IgG-Fc.
The Biochemical journal 2009;417(1):77-83.
2008: pablo emiliano tomatis; Stella M Fabiane; Fabio Simona; Paolo Carloni; Brian J Sutton; Alejandro J Vila
Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):20605-10.
2008: James Hunt; Marguerite G Bracher; Jianguo Shi; Sébastien Fleury; David Dombrowicz; Hannah J Gould; Brian J Sutton; Andrew John Beavil
Attenuation of IgE affinity for FcepsilonRI radically reduces the allergic response in vitro and in vivo.
The Journal of biological chemistry 2008;283(44):29882-7.
2008: Alexander Taylor; Hannah J Gould; Brian J Sutton; Rosaleen Ann Calvert
Avian IgY binds to a monocyte receptor with IgG-like kinetics despite an IgE-like structure.
The Journal of biological chemistry 2008;283(24):16384-90.
2008: Anna M Davies; Renée Tata; François Xavier Chauviac; Brian J Sutton; Paul R Brown
Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):338-42.
2008: Hannah J Gould; Brian J Sutton
IgE in allergy and asthma today.
Nature reviews. Immunology 2008;8(3):205-17.
2008: Katy J McCann; Christian H Ottensmeier; Alice Callard; Catherine M Radcliffe; David Harvey; Raymond A Dwek; Pauline M Rudd; Brian J Sutton; Paul Hobby; Freda K Stevenson
Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma.
Molecular immunology 2008;45(6):1567-72.
2008: Sophia N Karagiannis; Marguerite G Bracher; Rebecca L Beavil; Andrew John Beavil; James Hunt; Natalie McCloskey; Richard G Thompson; Nick East; Frances Burke; Brian J Sutton; David Dombrowicz; Frances R Balkwill; Hannah J Gould
Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells.
Cancer immunology, immunotherapy : CII 2008;57(2):247-63.
2007: Natalie McCloskey; James Hunt; Rebecca L Beavil; Mark R Jutton; Gabrielle J Grundy; Enrico Girardi; Stella M Fabiane; David J Fear; Daniel H Conrad; Brian J Sutton; Hannah J Gould
Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells.
The Journal of biological chemistry 2007;282(33):24083-91.
2007: Marguerite G Bracher; Hannah J Gould; Brian J Sutton; David Dombrowicz; Sophia N Karagiannis
Three-colour flow cytometric method to measure antibody-dependent tumour cell killing by cytotoxicity and phagocytosis.
Journal of immunological methods 2007;323(2):160-71.
2007: Leticia I Llarrull; Stella M Fabiane; Jason M Kowalski; Brian Bennett; Brian J Sutton; Alejandro J Vila
Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity.
The Journal of biological chemistry 2007;282(25):18276-85.
2007: Stéphane Duquerroy; Enrico A Stura; Stéphane Bressanelli; Stella M Fabiane; Marie-Christine Vaney; Dennis Beale; Maureen Hamon; Paolo Casali; Félix A Rey; Brian J Sutton; Michael J Taussig
Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation.
Journal of molecular biology 2007;368(5):1321-31.
2007: Alexander Taylor; Hannah J Gould; Brian J Sutton; Rosaleen Ann Calvert
The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL.
Immunogenetics 2007;59(4):323-8.
2007: Anna M Davies; Renée Tata; Rebecca L Beavil; Brian J Sutton; Paul R Brown
l-Methionine sulfoximine, but not phosphinothricin, is a substrate for an acetyltransferase (gene PA4866) from Pseudomonas aeruginosa: structural and functional studies.
Biochemistry 2007;46(7):1829-39.
2007: Hannah J Gould; Pooja Takhar; Helen E Harries; Elfy Chevretton; Brian J Sutton
The allergic march from Staphylococcus aureus superantigens to immunoglobulin E.
Chemical immunology and allergy 2007;93():106-36.
2006: Marlena Dubska; J Paul Banga; Danuta Plochocka; Grazyna Hoser; E Helen Kemp; Brian J Sutton; Andrzej Gardas; Monika Gora
Structural insights into autoreactive determinants in thyroid peroxidase composed of discontinuous and multiple key contact amino acid residues contributing to epitopes recognized by patients' autoantibodies.
Endocrinology 2006;147(12):5995-6003.
2005: Ruta Furmonaviciene; Brian J Sutton; Fabian Glaser; Charlie A Laughton; Nick Jones; Herb F Sewell; Farouk Shakib
An attempt to define allergen-specific molecular surface features: a bioinformatic approach.
Bioinformatics (Oxford, England) 2005;21(23):4201-4.
2005: Anna M Davies; Renée Tata; Riaz Agha; Brian J Sutton; Paul R Brown
Crystal structure of a putative phosphinothricin acetyltransferase (PA4866) from Pseudomonas aeruginosa PAC1.
Proteins 2005;61(3):677-9.
2005: Richard G Hibbert; Peter Teriete; Gabrielle J Grundy; Rebecca L Beavil; Rajko Reljic; V Michael Holers; Jonathan P Hannan; Brian J Sutton; Hannah J Gould; James M McDonnell
The structure of human CD23 and its interactions with IgE and CD21.
The Journal of experimental medicine 2005;202(6):751-60.
2005: Heather A Coker; Helen E Harries; Graham K Banfield; Victoria A Carr; Stephen R Durham; Elfy Chevretton; Paul Hobby; Brian J Sutton; Hannah J Gould
Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis.
The Journal of allergy and clinical immunology 2005;116(2):445-52.
2005: Jonathan S Oakhill; Brian J Sutton; Andrew R Gorringe; Robert W Evans
Homology modelling of transferrin-binding protein A from Neisseria meningitidis.
Protein engineering, design & selection : PEDS 2005;18(5):221-8.
2005: James Hunt; Rebecca L Beavil; Rosaleen Ann Calvert; Hannah J Gould; Brian J Sutton; Andrew John Beavil
Disulfide linkage controls the affinity and stoichiometry of IgE Fcepsilon3-4 binding to FcepsilonRI.
The Journal of biological chemistry 2005;280(17):16808-14.
2005: Anna M Davies; Rodolfo Maximiliano Rasia; Alejandro J Vila; Brian J Sutton; Stella M Fabiane
Effect of pH on the active site of an Arg121Cys mutant of the metallo-beta-lactamase from Bacillus cereus: implications for the enzyme mechanism.
Biochemistry 2005;44(12):4841-9.
2004: Monika Gora; Andrzej Gardas; Philip F Watson; Paul Hobby; Anthony P Weetman; Brian J Sutton; J Paul Banga
Key residues contributing to dominant conformational autoantigenic epitopes on thyroid peroxidase identified by mutagenesis.
Biochemical and biophysical research communications 2004;320(3):795-801.
2004: Monika Gora; Andrzej Gardas; W Wiktorowicz; Paul Hobby; Philip F Watson; Anthony P Weetman; Brian J Sutton; J Paul Banga
Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis.
Clinical and experimental immunology 2004;136(1):137-44.
2003: Hannah J Gould; Brian J Sutton; Andrew John Beavil; Rebecca L Beavil; Natalie McCloskey; Heather A Coker; David J Fear; Lyn Smurthwaite
The biology of IGE and the basis of allergic disease.
Annual review of immunology 2003;21():579-628.
2002: Marc Graille; Steven Harrison; Matthew Crump; Stuart C Findlow; Nicholas G Housden; Bruno H Muller; Nicole Battail-Poirot; Geneviève Sibaï; Brian J Sutton; Michael J Taussig; Colette Jolivet-Reynaud; Michael G Gore; Enrico A Stura
Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface.
The Journal of biological chemistry 2002;277(49):47500-6.
2002: Enrico A Stura; Michael J Taussig; Brian J Sutton; Stéphane Duquerroy; Stéphane Bressanelli; Anthony C Minson; Félix A Rey
Scaffolds for protein crystallisation.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 1):1715-21.
2002: Kathleen N Potter; Paul Hobby; Susanne Klijn; Freda K Stevenson; Brian J Sutton
Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigen.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(7):3777-82.
2002: Tommy Wan; Rebecca L Beavil; Stella M Fabiane; Andrew John Beavil; Maninder K Sohi; Maura Keown; Robert J Young; Alistair J Henry; Ray J Owens; Hannah J Gould; Brian J Sutton
The crystal structure of IgE Fc reveals an asymmetrically bent conformation.
Nature immunology 2002;3(7):681-6.
2002: Graham A Mackay; Mark D Hulett; Justin P D Cook; Halina M Trist; Alistair J Henry; James M McDonnell; Andrew John Beavil; Rebecca L Beavil; Brian J Sutton; P Mark Hogarth; Hannah J Gould
Mutagenesis within human FcepsilonRIalpha differentially affects human and murine IgE binding.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1787-95.
2002: John J Murphy; Paul Hobby; Juan Vilarino-Varela; Benjamin Bishop; Panagiota Iordanidou; Brian J Sutton; John D Norton
A novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesion.
The Biochemical journal 2002;361(Pt 3):431-6.
2001: Marc Graille; Enrico A Stura; Nicholas G Housden; Jennifer A Beckingham; Stephen P Bottomley; Dennis Beale; Michael J Taussig; Brian J Sutton; Michael G Gore; Jean-Baptiste Charbonnier
Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins.
Structure (London, England : 1993) 2001;9(8):679-87.
2001: Ian Kirby; R Lord; E Davison; Thomas J Wickham; Peter W Roelvink; Imre Kovesdi; Brian J Sutton; George Santis
Adenovirus type 9 fiber knob binds to the coxsackie B virus-adenovirus receptor (CAR) with lower affinity than fiber knobs of other CAR-binding adenovirus serotypes.
Journal of virology 2001;75(15):7210-4.
2001: Sophia N Karagiannis; J K Warrack; K H Jennings; PR Murdock; Graham R Christie; K Moulder; Brian J Sutton; Hannah J Gould
Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells.
Immunology 2001;103(3):319-31.
2001: James M McDonnell; Rosaleen Ann Calvert; Rebecca L Beavil; Andrew John Beavil; Alistair J Henry; Brian J Sutton; Hannah J Gould; David Cowburn
The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha.
Nature structural biology 2001;8(5):437-41.
2000: ER Eivazova; James M McDonnell; Brian J Sutton; Norman A Staines
Specificity and binding kinetics of murine lupus anti-DNA monoclonal antibodies implicate different stimuli for their production.
Immunology 2000;101(3):371-7.
2000: Alistair J Henry; James M McDonnell; R Ghirlando; Brian J Sutton; Hannah J Gould
Conformation of the isolated cepsilon3 domain of IgE and its complex with the high-affinity receptor, FcepsilonRI.
Biochemistry 2000;39(25):7406-13.
2000: Paul Hobby; Andrzej Gardas; Roman Radomski; Alan M McGregor; J Paul Banga; Brian J Sutton
Identification of an immunodominant region recognized by human autoantibodies in a three-dimensional model of thyroid peroxidase.
Endocrinology 2000;141(6):2018-26.
2000: Marc Graille; Enrico A Stura; Adam L Corper; Brian J Sutton; Michael J Taussig; Jean-Baptiste Charbonnier; Gregg J Silverman
Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5399-404.
2000: LJ Rigby; V C Epa; Graham A Mackay; Mark D Hulett; Brian J Sutton; Hannah J Gould; P Mark Hogarth
Domain one of the high affinity IgE receptor, FcepsilonRI, regulates binding to IgE through its interface with domain two.
The Journal of biological chemistry 2000;275(13):9664-72.
2000: Ian Kirby; E Davison; Andrew John Beavil; C P Soh; Thomas J Wickham; Peter W Roelvink; Imre Kovesdi; Brian J Sutton; George Santis
Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein.
Journal of virology 2000;74(6):2804-13.
2000: Mark K Boehm; Adam L Corper; Tommy Wan; Maninder K Sohi; Brian J Sutton; J D Thornton; P A Keep; Kerry A Chester; Richard H J Begent; Stephen J Perkins
Crystal structure of the anti-(carcinoembryonic antigen) single-chain Fv antibody MFE-23 and a model for antigen binding based on intermolecular contacts.
The Biochemical journal 2000;346 Pt 2():519-28.
2000: ER Eivazova; James M McDonnell; Brian J Sutton; Norman A Staines
Cross-reactivity of antiidiotypic antibodies with DNA in systemic lupus erythematosus.
Arthritis and rheumatism 2000;43(2):429-39.
2000: Brian J Sutton; Rebecca L Beavil; Andrew John Beavil
Inhibition of IgE-receptor interactions.
British medical bulletin 2000;56(4):1004-18.
2000: Andrzej Gardas; Philip F Watson; Paul Hobby; A Smith; Anthony P Weetman; Brian J Sutton; J Paul Banga
Human thyroid peroxidase: mapping of autoantibodies, conformational epitopes to the enzyme surface.
Redox report : communications in free radical research 2000;5(4):237-41.
1999: Ian Kirby; E Davison; Andrew John Beavil; C P Soh; Thomas J Wickham; Peter W Roelvink; Imre Kovesdi; Brian J Sutton; George Santis
Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR.
Journal of virology 1999;73(11):9508-14.
1999: Andrzej Gardas; Brian J Sutton; Urszula Piotrowska; Z Pasieka; P S Barnett; G Huang; Alan M McGregor; J Paul Banga
Distinct immunological and biochemical properties of thyroid peroxidase purified from human thyroid glands and recombinant protein produced in insect cells.
Biochimica et biophysica acta 1999;1433(1-2):229-39.
1999: Donald MacGlashan; Lawrence M Lichtenstein; J McKenzie-White; KRISTIN CHICHESTER; Alistair J Henry; Brian J Sutton; Hannah J Gould
Upregulation of FcepsilonRI on human basophils by IgE antibody is mediated by interaction of IgE with FcepsilonRI.
The Journal of allergy and clinical immunology 1999;104(2 Pt 1):492-8.
1999: Sebastien Farnaud; Renée Tata; Maninder K Sohi; Tommy Wan; Paul R Brown; Brian J Sutton
Evidence that cysteine-166 is the active-site nucleophile of Pseudomonas aeruginosa amidase: crystallization and preliminary X-ray diffraction analysis of the enzyme.
The Biochemical journal 1999;340 ( Pt 3)():711-4.
1999: Jennifer A Beckingham; Stephen P Bottomley; R Hinton; Brian J Sutton; Michael G Gore
Interactions between a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus and a human kappa light chain.
The Biochemical journal 1999;340 ( Pt 1)():193-9.
1998: Paul Hobby; Frank J Ward; AN Denbury; D G Williams; Norman A Staines; Brian J Sutton
Molecular modeling of an anti-DNA autoantibody (V-88) and mapping of its V region epitopes recognized by heterologous and autoimmune antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(6):2944-52.
1998: Stella M Fabiane; Maninder K Sohi; Tommy Wan; David J Payne; John H Bateson; T Mitchell; Brian J Sutton
Crystal structure of the zinc-dependent beta-lactamase from Bacillus cereus at 1.9 A resolution: binuclear active site with features of a mononuclear enzyme.
Biochemistry 1998;37(36):12404-11.
1998: Maura Keown; Alistair J Henry; R Ghirlando; Brian J Sutton; Hannah J Gould
Thermodynamics of the interaction of human immunoglobulin E with its high-affinity receptor Fc epsilon RI.
Biochemistry 1998;37(25):8863-9.
1998: Brian J Sutton; Adam L Corper; Maninder K Sohi; R Jefferis; Dennis Beale; Michael J Taussig
The structure of a human rheumatoid factor bound to IgG Fc.
Advances in experimental medicine and biology 1998;435():41-50.
1997: Justin P D Cook; Alistair J Henry; James M McDonnell; Ray J Owens; Brian J Sutton; Hannah J Gould
Identification of contact residues in the IgE binding site of human FcepsilonRIalpha.
Biochemistry 1997;36(50):15579-88.
1997: Alistair J Henry; Justin P D Cook; James M McDonnell; Graham A Mackay; J Shi; Brian J Sutton; Hannah J Gould
Participation of the N-terminal region of Cepsilon3 in the binding of human IgE to its high-affinity receptor FcepsilonRI.
Biochemistry 1997;36(50):15568-78.
1997: Andrzej Gardas; A Lewartowska; Brian J Sutton; Z Pasieka; Alan M McGregor; J Paul Banga
Human thyroid peroxidase (TPO) isoforms, TPO-1 and TPO-2: analysis of protein expression in Graves' thyroid tissue.
The Journal of clinical endocrinology and metabolism 1997;82(11):3752-7.
1997: Robert Korngold; B A Jameson; James M McDonnell; C Leighton; Brian J Sutton; Hannah J Gould; George F Murphy
Peptide analogs that inhibit IgE-Fc epsilon RI alpha interactions ameliorate the development of lethal graft-versus-host disease.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1997;3(4):187-93.
1997: Andrzej Gardas; Maninder K Sohi; Brian J Sutton; Alan M McGregor; J Paul Banga
Purification and crystallisation of the autoantigen thyroid peroxidase from human Graves' thyroid tissue.
Biochemical and biophysical research communications 1997;234(2):366-70.
1997: James M McDonnell; Andrew John Beavil; Graham A Mackay; Alistair J Henry; Justin P D Cook; Hannah J Gould; Brian J Sutton
Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI.
Biochemical Society transactions 1997;25(2):387-92.
1997: Adam L Corper; Maninder K Sohi; Vincent Bonagura; M Steinitz; R Jefferis; A Feinstein; Dennis Beale; Michael J Taussig; Brian J Sutton
Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction.
Nature structural biology 1997;4(5):374-81.
1997: O Schulz; Brian J Sutton; Rebecca L Beavil; J Shi; Herb F Sewell; Hannah J Gould; P Laing; Farouk Shakib
Cleavage of the low-affinity receptor for human IgE (CD23) by a mite cysteine protease: nature of the cleaved fragment in relation to the structure and function of CD23.
European journal of immunology 1997;27(3):584-8.
1997: J Shi; R Ghirlando; Rebecca L Beavil; Andrew John Beavil; Maura Keown; R J Young; Ray J Owens; Brian J Sutton; Hannah J Gould
Interaction of the low-affinity receptor CD23/Fc epsilonRII lectin domain with the Fc epsilon3-4 fragment of human immunoglobulin E.
Biochemistry 1997;36(8):2112-22.
1997: Maura Keown; R Ghirlando; Graham A Mackay; Brian J Sutton; Hannah J Gould
Basis of the 1:1 stoichiometry of the high affinity receptor Fc epsilon RI-IgE complex.
European biophysics journal : EBJ 1997;25(5-6):471-6.
1996: Maninder K Sohi; Adam L Corper; Tommy Wan; M Steinitz; R Jefferis; Dennis Beale; M He; A Feinstein; Brian J Sutton; Michael J Taussig
Crystallization of a complex between the Fab fragment of a human immunoglobulin M (IgM) rheumatoid factor (RF-AN) and the Fc fragment of human IgG4.
Immunology 1996;88(4):636-41.
1996: James M McDonnell; Andrew John Beavil; Graham A Mackay; B A Jameson; Robert Korngold; Hannah J Gould; Brian J Sutton
Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor.
Nature structural biology 1996;3(5):419-26.
1995: Maninder K Sohi; Tommy Wan; Brian J Sutton; T Atkinson; M A Atkinson; J P Murphy; Stephen P Bottomley; Michael G Gore
Crystallization and X-ray analysis of a single fab binding domain from protein L of Peptostreptococcus magnus.
Proteins 1995;23(4):610-2.
1995: Andrew John Beavil; R J Young; Brian J Sutton; S J Perkins
Bent domain structure of recombinant human IgE-Fc in solution by X-ray and neutron scattering in conjunction with an automated curve fitting procedure.
Biochemistry 1995;34(44):14449-61.
1995: K N Walker; Stephen P Bottomley; A G Popplewell; Brian J Sutton; Michael G Gore
Equilibrium and pre-equilibrium fluorescence spectroscopic studies of the binding of a single-immunoglobulin-binding domain derived from protein G to the Fc fragment from human IgG1.
The Biochemical journal 1995;310 ( Pt 1)():177-84.
1995: Stephen P Bottomley; Brian J Sutton; Michael G Gore
Elution of human IgG from affinity columns containing immobilised variants of protein A.
Journal of immunological methods 1995;182(2):185-92.
1995: Maura Keown; R Ghirlando; R J Young; Andrew John Beavil; R J Owens; S J Perkins; Brian J Sutton; Hannah J Gould
Hydrodynamic studies of a complex between the Fc fragment of human IgE and a soluble fragment of the Fc epsilon RI alpha chain.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):1841-5.
1995: R J Young; R J Owens; Graham A Mackay; C M Chan; J Shi; M Hide; D M Francis; Alistair J Henry; Brian J Sutton; Hannah J Gould
Secretion of recombinant human IgE-Fc by mammalian cells and biological activity of glycosylation site mutants.
Protein engineering 1995;8(2):193-9.
1994: Stephen P Bottomley; A G Popplewell; M Scawen; T Wan; Brian J Sutton; Michael G Gore
The stability and unfolding of an IgG binding protein based upon the B domain of protein A from Staphylococcus aureus probed by tryptophan substitution and fluorescence spectroscopy.
Protein engineering 1994;7(12):1463-70.
1994: Maninder K Sohi; Brian J Sutton; Adam L Corper; Tommy Wan; R N Maini; C Brown; T Rijnders; Dennis Beale; A Feinstein; A S Humphreys
Crystallization and preliminary X-ray analysis of the Fab fragment of a human monoclonal IgM rheumatoid factor (2A2).
Journal of molecular biology 1994;242(5):706-8.
1994: Brian J Sutton; Maninder K Sohi
Crystallization of membrane proteins for X-ray analysis.
Methods in molecular biology (Clifton, N.J.) 1994;27():1-18.
1993: Brian J Sutton; Hannah J Gould
The human IgE network.
Nature 1993;366(6454):421-8.
1993: Andrew John Beavil; Rebecca L Beavil; C M Chan; Justin P D Cook; Hannah J Gould; Alistair J Henry; R J Owens; J Shi; Brian J Sutton; R J Young
Structural basis of the IgE-Fc epsilon RI interaction.
Biochemical Society transactions 1993;21(4):968-72.
1992: Andrew John Beavil; R L Edmeades; Hannah J Gould; Brian J Sutton
Alpha-helical coiled-coil stalks in the low-affinity receptor for IgE (Fc epsilon RII/CD23) and related C-type lectins.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):753-7.
1990: J Paul Banga; D Mahadevan; G J Barton; Brian J Sutton; J W Saldanha; E Odell; Alan M McGregor
Prediction of domain organisation and secondary structure of thyroid peroxidase, a human autoantigen involved in destructive thyroiditis.
FEBS letters 1990;266(1-2):133-41.
1988: Brian J Sutton
Antigen recognition by B cells: antibody-antigen interactions at the atomic level.
Immunology. Supplement 1988;1():31-4.