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Bo Ahrén

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Chemicals & Drugs

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Islets of Langerhans

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TOP 3
L Ohlsson; Giovanni Pacini; A Tura; W Alsalim; Richard D Carr; A Mari; Bo Ahrén
Glucose-lowering effect of the DPP-4 inhibitor sitagliptin after glucose and non-glucose macronutrient ingestion in non-diabetic subjects.
Bo Ahrén
Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes.
L Ahlkvist; Giovanni Pacini; Jenny Vikman; Bo Ahrén
Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice.

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2013: L Ohlsson; Giovanni Pacini; A Tura; W Alsalim; Richard D Carr; A Mari; Bo Ahrén
Glucose-lowering effect of the DPP-4 inhibitor sitagliptin after glucose and non-glucose macronutrient ingestion in non-diabetic subjects.
Diabetes, obesity & metabolism 2013;15(6):531-7.
2013: Bo Ahrén
Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes.
Vascular health and risk management 2013;9():155-63.
2012: L Ahlkvist; Giovanni Pacini; Jenny Vikman; Bo Ahrén
Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice.
Regulatory peptides 2012;178(1-3):29-35.
2012: Bilal Omar; Giovanni Pacini; Bo Ahrén
Differential development of glucose intolerance and pancreatic islet adaptation in multiple diet induced obesity models.
Nutrients 2012;4(10):1367-81.
2012: Johan Farngren; James E Foley; Margaretha Persson; Anja Schweizer; Bo Ahrén
Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2012;97(10):3799-806.
2012: Carolyn F Deacon; E Mannucci; Bo Ahrén
Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes-a review and meta analysis.
Diabetes, obesity & metabolism 2012;14(8):762-7.
2012: Carl-David Agardh; Bo Ahrén; Ragnar Hanås; Stefan Jansson; Ulf Smith; Eva Toft; Claes-Göran Ostenson
[Warning against uncritical use of overweight surgery in type 2 diabetes].
Läkartidningen 2012;109(25):1208-9.
2012: Bo Ahrén
Incretin hormones and the up-regulation of insulin secretion in insulin resistance.
The Journal of clinical endocrinology and metabolism 2012;97(4):1173-5.
2012: Carl-David Agardh; Bo Ahrén
Switching from high-fat to low-fat diet normalizes glucose metabolism and improves glucose-stimulated insulin secretion and insulin sensitivity but not body weight in C57BL/6J mice.
Pancreas 2012;41(2):253-7.
2012: Bengt Vessby; Eva Warensjö; Bo Ahrén; F Lindgärde
Plasma lipid fatty acid composition, desaturase activities and insulin sensitivity in Amerindian women.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2012;22(3):176-81.
2011: Bo Ahrén
The future of incretin-based therapy: novel avenues--novel targets.
Diabetes, obesity & metabolism 2011;13 Suppl 1():158-66.
2011: O Lindgren; Richard D Carr; Carolyn F Deacon; Jens Juul Holst; Bo Ahrén
Dissociated incretin hormone response to protein versus fat ingestion in obese subjects.
Diabetes, obesity & metabolism 2011;13(9):863-5.
2011: Bo Ahrén; Sylvie Dejager; Beth E Dunning; A Schweizer; Edwin B Villhauer; James Foley
Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans.
Diabetes, obesity & metabolism 2011;13(9):775-83.
2011: Ola Lindgren; Andrea Mari; Giovanni Pacini; Richard D Carr; Carolyn F Deacon; Jens J Holst; Bo Ahrén
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans.
The Journal of clinical endocrinology and metabolism 2011;96(8):2519-24.
2011: Maria Sörhede Winzell; Matthew Coghlan; Georgia Frangioudakis; Brendan Leighton; David M Smith; Leonard H Storlien; Bo Ahrén
Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice.
European journal of pharmacology 2011;663(1-3):80-6.
2011: Bo Ahrén
Are sulfonylureas less desirable than DPP-4 inhibitors as add-on to metformin in the treatment of type 2 diabetes?
Current diabetes reports 2011;11(2):83-90.
2011: Bo Ahrén; James Foley; E Bosi
Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin.
Diabetes, obesity & metabolism 2011;13(3):193-203.
2011: Carolyn F Deacon; Bo Ahrén
Physiology of incretins in health and disease.
The review of diabetic studies : RDS 2011;8(3):293-306.
2010: Jonatan Ahrén; Bo Ahrén; Nils Wierup
Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months.
Islets 2010;2(6):353-6.
2010: Sara Bromander; Rolf Anckarsäter; Bo Ahrén; Marianne Kristiansson; Kaj Blennow; Agneta Holmäng; Henrik Zetterberg; Henrik Anckarsäter; Caroline E Wass
Cerebrospinal fluid insulin during non-neurological surgery.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(10):1167-70.
2010: Rickard Westergren; Daniel Nilsson; Mikael Heglind; Zahra Arani; Mats Grände; Anna Cederberg; Bo Ahrén; Sven Enerbäck
Overexpression of Foxf2 in adipose tissue is associated with lower levels of IRS1 and decreased glucose uptake in vivo.
American journal of physiology. Endocrinology and metabolism 2010;298(3):E548-54.
2010: Bo Ahrén
Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin.
Diabetes, metabolic syndrome and obesity : targets and therapy 2010;3():31-41.
2010: Tommy Jönsson; YE Granfeldt; Charlotte Erlanson-Albertsson; Bo Ahrén; Staffan Lindeberg
A paleolithic diet is more satiating per calorie than a mediterranean-like diet in individuals with ischemic heart disease.
Nutrition & metabolism 2010;7():85.
2010: Bo Ahrén; Richard D Carr; Carolyn F Deacon
Incretin hormone secretion over the day.
Vitamins and hormones 2010;84():203-20.
2010: Jie Mei; Shukun Yu; Bo Ahrén
Study on administration of 1,5-anhydro-D-fructose in C57BL/6J mice challenged with high-fat diet.
BMC endocrine disorders 2010;10():17.
2009: Jenny Vikman; Bo Ahrén
Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets.
Diabetes, obesity & metabolism 2009;11 Suppl 4():197-201.
2009: Marie Guldstrand; Bo Ahrén; Erik Näslund; Jens Juul Holst; Ulf Adamson
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery.
Diabetes, obesity & metabolism 2009;11(11):1027-33.
2009: Bo Ahrén
Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events.
Best practice & research. Clinical endocrinology & metabolism 2009;23(4):487-98.
2009: Ola Lindgren; Andrea Mari; Carolyn F Deacon; Richard D Carr; Maria Sörhede Winzell; Jenny Vikman; Bo Ahrén
Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men.
The Journal of clinical endocrinology and metabolism 2009;94(8):2887-92.
2009: Sofie Westling; Bo Ahrén; Charlotta Sunnqvist; Lil Träskman-Bendz
Altered glucose tolerance in women with deliberate self-harm.
Psychoneuroendocrinology 2009;34(6):878-83.
2009: Bo Ahrén; A Mari; C L Fyfe; Fotini Tsofliou; Alan A Sneddon; Klaus W J Wahle; Maria Sörhede Winzell; Giovanni Pacini; Lynda M Williams
Effects of conjugated linoleic acid plus n-3 polyunsaturated fatty acids on insulin secretion and estimated insulin sensitivity in men.
European journal of clinical nutrition 2009;63(6):778-86.
2009: Bo Ahrén
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes.
Nature reviews. Drug discovery 2009;8(5):369-85.
2009: Bo Ahrén; Anja Schweizer; Sylvie Dejager; Beth E Dunning; Peter M Nilsson; Margaretha Persson; James Foley
Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(4):1236-43.
2009: Sofia Rengman; Björn Weström; Bo Ahrén; Stefan G Pierzynowski
Arterial gastroduodenal infusion of cholecystokinin-33 stimulates the exocrine pancreatic enzyme release via an enteropancreatic reflex, without affecting the endocrine insulin secretion in pigs.
Pancreas 2009;38(2):213-8.
2009: Tommy Jönsson; YE Granfeldt; Bo Ahrén; Ulla-Carin Branell; Gunvor Pålsson; Anita Hansson; Margareta Söderström; Staffan Lindeberg
Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.
Cardiovascular diabetology 2009;8():35.
2008: Bo Ahrén
Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes.
Expert opinion on emerging drugs 2008;13(4):593-607.
2008: Maria A Eriksson; Eva Rask; Owe Johnson; Kjell Carlström; Bo Ahrén; Mats Eliasson; Kurt Boman; Siv Söderberg
Sex-related differences in the associations between hyperleptinemia, insulin resistance and dysfibrinolysis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2008;19(7):625-32.
2008: Richard D Carr; Marianne O Larsen; Maria Sörhede Winzell; Katarina Jelic; Ola Lindgren; Carolyn F Deacon; Bo Ahrén
Incretin and islet hormonal responses to fat and protein ingestion in healthy men.
American journal of physiology. Endocrinology and metabolism 2008;295(4):E779-84.
2008: Magnus Dencker; Ola Thorsson; Magnus K Karlsson; Christian Lindén; Stig Eiberg; Per Wollmer; Lars Bo Andersen; Bo Ahrén
Body fat related to daily physical activity and insulin concentrations in non-diabetic children.
Clinical physiology and functional imaging 2008;28(4):211-5.
2008: Bo Ahrén
Evidence that autonomic mechanisms contribute to the adaptive increase in insulin secretion during dexamethasone-induced insulin resistance in humans.
Diabetologia 2008;51(6):1018-24.
2008: Bo Ahrén; Richard E Pratley; Mazin Soubt; Beth E Dunning; James Foley
Clinical measures of islet function: usefulness to characterize defects in diabetes.
Current diabetes reviews 2008;4(2):129-45.
2008: Bo Ahrén; Maria Sörhede Winzell; Giovanni Pacini
The augmenting effect on insulin secretion by oral versus intravenous glucose is exaggerated by high-fat diet in mice.
The Journal of endocrinology 2008;197(1):181-7.
2008: Bo Ahrén; James Foley
The islet enhancer vildagliptin: mechanisms of improved glucose metabolism.
International journal of clinical practice. Supplement 2008;(159):8-14.
2008: Maria Sörhede Winzell; Bo Ahrén
Durable islet effects on insulin secretion and protein kinase A expression following exendin-4 treatment of high-fat diet-fed mice.
Journal of molecular endocrinology 2008;40(2):93-100.
2008: Bo Ahrén; Maria Sörhede-Winzell
Disturbed alpha-cell function in mice with beta-cell specific overexpression of human islet amyloid polypeptide.
Experimental diabetes research 2008;2008():304513.
2008: Bo Ahrén
Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin.
Vascular health and risk management 2008;4(2):383-94.
2008: Jo W M Höppener; HM Jacobs; N Wierup; G Sotthewes; M Sprong; P de Vos; R Berger; F Sundler; Bo Ahrén
Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.
Experimental diabetes research 2008;2008():697035.
2007: Bo Ahrén
[Two breakthroughs in the treatment of type 2 diabetes. Both the receptor agonist and enzyme inhibitors now available in the clinic].
Läkartidningen 2007;104(49-50):3763-4.
2007: Bo Ahrén
DPP-4 inhibitors.
Best practice & research. Clinical endocrinology & metabolism 2007;21(4):517-33.
2007: Maria Sörhede Winzell; Bo Ahrén
G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.
Pharmacology & therapeutics 2007;116(3):437-48.
2007: Bo Ahrén; G Pacini; A Tura; James Foley; A Schweizer
Improved meal-related insulin processing contributes to the enhancement of B-cell function by the DPP-4 inhibitor vildagliptin in patients with type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2007;39(11):826-9.
2007: Bo Ahrén; Maria Sörhede Winzell; Nils Wierup; Frank Sundler; Bryan Burkey; Thomas Hughes
DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.
Regulatory peptides 2007;143(1-3):97-103.
2007: Bo Ahrén
GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors.
Current diabetes reports 2007;7(5):340-7.
2007: Staffan Lindeberg; Tommy Jönsson; Y Granfeldt; E Borgstrand; J Soffman; K Sjöström; Bo Ahrén
A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease.
Diabetologia 2007;50(9):1795-807.
2007: Maria Sörhede Winzell; Bo Ahrén
Role of VIP and PACAP in islet function.
Peptides 2007;28(9):1805-13.
2007: Folke Lindgärde; Bo Ahrén
Improved metabolic risk markers following two 6-month physical activity programs among socioeconomic marginalized women of Native American ancestry in Lima, Peru.
Diabetes care 2007;30(9):2230-2.
2007: Bo Ahrén
Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications.
Diabetes care 2007;30(6):1344-50.
2007: Cecilia Mattsson; Eva Rask; Kjell Carlström; Jonas Andersson; Mats Eliasson; Bo Ahrén; Siv Söderberg; Tommy Olsson
Gender-specific links between hepatic 11beta reduction of cortisone and adipokines.
Obesity (Silver Spring, Md.) 2007;15(4):887-94.
2007: Erik Flodgren; Björn Olde; Sandra Meidute-Abaraviciene; Maria Sörhede Winzell; Bo Ahrén; Albert Salehi
GPR40 is expressed in glucagon producing cells and affects glucagon secretion.
Biochemical and biophysical research communications 2007;354(1):240-5.
2007: Bo Ahrén
Insulin secretion and insulin sensitivity in relation to fasting glucose in healthy subjects.
Diabetes care 2007;30(3):644-8.
2007: Astrid H Petersen; Torben Laursen; Bo Ahrén; Thomas R Pieber; Per Clauson; Per Wollmer
The impact of large tidal volume ventilation on the absorption of inhaled insulin in rabbits.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(3-4):351-7.
2007: Dorte X Gram; Bo Ahrén; Istvan Nagy; Uffe B Olsen; Christian L Brand; Frank Sundler; René Tabanera; Ove Svendsen; Richard D Carr; Peter Santha; Nils Wierup; Anders J Hansen
Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.
The European journal of neuroscience 2007;25(1):213-23.
2007: Maria Sörhede Winzell; Caroline Magnusson; Bo Ahrén
Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice.
Metabolism: clinical and experimental 2007;56(1):122-8.
2006: Folke Lindgärde; Bengt Vessby; Bo Ahrén
Serum cholesteryl fatty acid composition and plasma glucose concentrations in Amerindian women.
The American journal of clinical nutrition 2006;84(5):1009-13.
2006: Bo Ahrén
[Clinical research must be based on teaming physician and researcher].
Läkartidningen 2006;103(36):2575.
2006: Magnus Dencker; Ola Thorsson; Magnus K Karlsson; Christian Lindén; Per Wollmer; Bo Ahrén
Leptin is closely related to body fat in prepubertal children aged 8-11 years.
Acta paediatrica (Oslo, Norway : 1992) 2006;95(8):975-9.
2006: P Thomas Gunnarsson; Maria Sörhede Winzell; Carolyn F Deacon; Marianne O Larsen; Katarina Jelic; Richard D Carr; Bo Ahrén
Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice.
Endocrinology 2006;147(7):3173-80.
2006: Bo Ahrén; Giovanni Pacini
A novel approach to assess insulin sensitivity reveals no increased insulin sensitivity in mice with a dominant-negative mutant hepatocyte nuclear factor-1alpha.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(1):R131-7.
2006: Helena A Walz; Linda Härndahl; Nils Wierup; Emilia Zmuda-Trzebiatowska; Fredrik Svennelid; Vincent C Manganiello; Thorkil Ploug; Frank Sundler; Eva Degerman; Bo Ahrén; Lena Stenson Holst
Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.
The Journal of endocrinology 2006;189(3):629-41.
2006: Madeléne Sandqvist; Else Hellebö Johanson; Bo Ahrén; Mette Axelsen; Martin Schmelz; Ulf Smith; Per-Anders Jansson
Postprandial interstitial insulin concentrations in type 2 diabetes relatives.
European journal of clinical investigation 2006;36(6):383-8.
2006: Maria C García; Ingrid Wernstedt; Anna Berndtsson; Maria Enge; Michal Bell; Olof H Hultgren; Michael Horn; Bo Ahrén; Sven Enerback; Claes Ohlsson; Ville Wallenius; John-Olov Jansson
Mature-onset obesity in interleukin-1 receptor I knockout mice.
Diabetes 2006;55(5):1205-13.
2006: Cecilia Follin; Ulf Thilén; Bo Ahrén; Eva Marie Erfurth
Improvement in cardiac systolic function and reduced prevalence of metabolic syndrome after two years of growth hormone (GH) treatment in GH-deficient adult survivors of childhood-onset acute lymphoblastic leukemia.
The Journal of clinical endocrinology and metabolism 2006;91(5):1872-5.
2006: Ning Xu; Peter Nilsson-Ehle; Bo Ahrén
Suppression of apolipoprotein M expression and secretion in alloxan-diabetic mouse: Partial reversal by insulin.
Biochemical and biophysical research communications 2006;342(4):1174-7.
2006: Bo Ahrén
Vildagliptin: an inhibitor of dipeptidyl peptidase-4 with antidiabetic properties.
Expert opinion on investigational drugs 2006;15(4):431-42.
2006: Bo Ahrén
The insulin response to gastric glucose is reduced in PAC1 and GRP receptor gene deleted mice.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16 Suppl 1():S17-21.
2006: Maria Sörhede Winzell; Kristoffer Ström; Cecilia Holm; Bo Ahrén
Glucose-stimulated insulin secretion correlates with beta-cell lipolysis.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16 Suppl 1():S11-6.
2006: Bo Ahrén; Giovanni Pacini
Contributions from the first SICOD (Swedish-Italian Cooperation on Diabetes Research) meeting, Stockholm, Sweden, October 2004.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2006;16 Suppl 1():S1-2.
2006: Birgitta Bülow; Svante Jansson; Claes Juhlin; Lars Steen; Marja Thorén; Hans Wahrenberg; Stig Valdemarsson; Bo Wängberg; Bo Ahrén
Adrenal incidentaloma - follow-up results from a Swedish prospective study.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(3):419-23.
2006: Ning Xu; Bo Ahrén; Jingting Jiang; Peter Nilsson-Ehle
Down-regulation of apolipoprotein M expression is mediated by phosphatidylinositol 3-kinase in HepG2 cells.
Biochimica et biophysica acta 2006;1761(2):256-60.
2006: Maria Sörhede Winzell; Giovanni Pacini; Bo Ahrén
Insulin secretion after dietary supplementation with conjugated linoleic acids and n-3 polyunsaturated fatty acids in normal and insulin-resistant mice.
American journal of physiology. Endocrinology and metabolism 2006;290(2):E347-54.
2006: Tommy Jönsson; Bo Ahrén; Giovanni Pacini; Frank Sundler; Nils Wierup; Stig Steen; Trygve Sjöberg; Martin Ugander; Johan Frostegård; Leif Göransson; Staffan Lindeberg
A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs.
Nutrition & metabolism 2006;3():39.
2006: Ann Linderoth; Olena Prykhod'ko; Bo Ahrén; Frida Fåk; Stefan G Pierzynowski; Björn Weström
Binding and the effect of the red kidney bean lectin, phytohaemagglutinin, in the gastrointestinal tract of suckling rats.
The British journal of nutrition 2006;95(1):105-15.
2006: Bo Ahrén
Glucagon secretion in relation to insulin sensitivity in healthy subjects.
Diabetologia 2006;49(1):117-22.
2005: Dorte X Gram; Anders J Hansen; Michael Wilken; Torben Elm; Ove Svendsen; Richard D Carr; Bo Ahrén; Christian L Brand
Plasma calcitonin gene-related peptide is increased prior to obesity, and sensory nerve desensitization by capsaicin improves oral glucose tolerance in obese Zucker rats.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(6):963-9.
2005: Maria Sörhede-Winzell; Caroline Magnusson; Bo Ahrén
The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice.
Regulatory peptides 2005;131(1-3):12-7.
2005: Bo Ahrén; Maria Sörhede-Winzell; Bryan Burkey; Thomas Hughes
Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.
European journal of pharmacology 2005;521(1-3):164-8.
2005: Bo Ahrén; K Thomaseth; G Pacini
Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice.
Diabetologia 2005;48(10):2140-6.
2005: Andrea Mari; Bo Ahrén; Giovanni Pacini
Assessment of insulin secretion in relation to insulin resistance.
Current opinion in clinical nutrition and metabolic care 2005;8(5):529-33.
2005: Bo Ahrén; Giovanni Pacini; James Foley; Anja Schweizer
Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year.
Diabetes care 2005;28(8):1936-40.
2005: Kurt Borch; Bo Ahrén; Håkan Ahlman; Sture Falkmer; Göran Granérus; Lars Grimelius
Gastric carcinoids: biologic behavior and prognosis after differentiated treatment in relation to type.
Annals of surgery 2005;242(1):64-73.
2005: Sophia G Moesgaard; Christian L Brand; Jeppe Sturis; Bo Ahrén; Michael Wilken; Jan Fleckner; Richard D Carr; Ove Svendsen; Anders J Hansen; Dorte X Gram
Sensory nerve inactivation by resiniferatoxin improves insulin sensitivity in male obese Zucker rats.
American journal of physiology. Endocrinology and metabolism 2005;288(6):E1137-45.
2005: Bo Ahrén
Type 2 diabetes, insulin secretion and beta-cell mass.
Current molecular medicine 2005;5(3):275-86.
2005: Madeléne Sandqvist; Gunnar Nyberg; Ann Hammarstedt; Natalia Klintland; Silvia Gogg; Kenneth Caidahl; Bo Ahrén; Ulf Smith; Per-Anders Jansson
Low adipocyte IRS-1 protein expression is associated with an increased arterial stiffness in non-diabetic males.
Atherosclerosis 2005;180(1):119-25.
2005: Bo Ahrén
What mediates the benefits associated with dipeptidyl peptidase-IV inhibition?
Diabetologia 2005;48(4):605-7.
2005: Bo Ahrén; Thomas Hughes
Inhibition of dipeptidyl peptidase-4 augments insulin secretion in response to exogenously administered glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, pituitary adenylate cyclase-activating polypeptide, and gastrin-releasing peptide in mice.
Endocrinology 2005;146(4):2055-9.
2005: Bo Ahrén
[New strategy in type 2 diabetes tested in clinical trials. Glucagon-like peptide 1 (GLP-1) affects basic caused of the disease].
Läkartidningen 2005;102(8):545-9.
2005: Dorte X Gram; Anders J Hansen; Carolyn F Deacon; Christian L Brand; Ulla Ribel; Michael Wilken; Richard D Carr; Ove Svendsen; Bo Ahrén
Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV.
European journal of pharmacology 2005;509(2-3):211-7.
2005: Bob Olsson; Mohammad Bohlooly-Y; Sharyn Fitzgerald; Fredrik Frick; Anna Ljungberg; Bo Ahrén; Jan Törnell; Göran Bergström; Jan Oscarsson
Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.
Endocrinology 2005;146(2):920-30.
2005: Lina Akesson; Bo Ahrén; Gudrun Edgren; Eva Degerman
VPAC2-R mediates the lipolytic effects of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide in primary rat adipocytes.
Endocrinology 2005;146(2):744-50.
2005: Tommy Jönsson; Stefan Olsson; Bo Ahrén; Thorkild Bøg-Hansen; Anita Dole; Staffan Lindeberg
Agrarian diet and diseases of affluence--do evolutionary novel dietary lectins cause leptin resistance?
BMC endocrine disorders 2005;5():10.
2005: Jie Mei; Shukun Yu; Bo Ahrén
A 90-day toxicological evaluation of 1,5-anhydro-d-fructose in Sprague-Dawley rats.
Drug and chemical toxicology 2005;28(3):263-72.
2005: Bo Ahrén; G Pacini
Islet adaptation to insulin resistance: mechanisms and implications for intervention.
Diabetes, obesity & metabolism 2005;7(1):2-8.
2005: Mohammad Bohlooly-Y; Mohammad Bohlooly; Bob Olsson; Carl Bruder; Daniel Lindén; Klara Sjögren; Mikael Bjursell; Emil Egecioglu; Lennart Svensson; Peter Brodin; John C Waterton; Olle G P Isaksson; Frank Sundler; Bo Ahrén; Claes Ohlsson; Jan Oscarsson; Jan Törnell
Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.
Diabetes 2005;54(1):51-62.
2005: L Evilevitch; Stefan G Pierzynowski; Ann Linderoth; Bo Ahrén; Charlotte Erlanson-Albertsson; Malgorzata Podgurniak; Björn Weström
Three-day enteral exposure to a red kidney bean lectin preparation enhances the pancreatic response to CCK stimulation in suckling pigs.
Biology of the neonate 2005;87(1):20-5.
2004: Sofie Westling; Bo Ahrén; Lil Träskman-Bendz; Asa Westrin
High CSF-insulin in violent suicide attempters.
Psychiatry research 2004;129(3):249-55.
2004: Birgitta Bülow; Katarina Link; Bo Ahrén; Ann-Sofie Nilsson; Eva Marie Erfurth
Survivors of childhood acute lymphoblastic leukaemia, with radiation-induced GH deficiency, exhibit hyperleptinaemia and impaired insulin sensitivity, unaffected by 12 months of GH treatment.
Clinical endocrinology 2004;61(6):683-91.
2004: Bo Ahrén; Ramon Gomis; Eberhard Standl; David Mills; Anja Schweizer
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes.
Diabetes care 2004;27(12):2874-80.
2004: Maria Sörhede Winzell; Giovanni Pacini; Claes B Wollheim; Bo Ahrén
Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues.
Diabetes 2004;53 Suppl 3():S92-6.
2004: Maria Sörhede Winzell; Bo Ahrén
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes.
Diabetes 2004;53 Suppl 3():S215-9.
2004: Thomas Nyström; Mark K Gutniak; Qimin Zhang; Fan Zhang; Jens Juul Holst; Bo Ahrén; Ake Sjöholm
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.
American journal of physiology. Endocrinology and metabolism 2004;287(6):E1209-15.
2004: Bo Ahrén; O Schmitz
GLP-1 receptor agonists and DPP-4 inhibitors in the treatment of type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(11-12):867-76.
2004: Bo Ahrén
GLP-1 and extra-islet effects.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(11-12):842-5.
2004: M Sörhede Winzell; Bo Ahrén
Glucagon-like peptide-1 and islet lipolysis.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(11-12):795-803.
2004: Ning Xu; Peter Nilsson-Ehle; Bo Ahrén
Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects.
The Journal of nutritional biochemistry 2004;15(10):579-82.
2004: Katarina Link; Christian Moëll; Stanislaw Garwicz; Eva Cavallin-Ståhl; Jonas Björk; Ulf Thilén; Bo Ahrén; Eva Marie Erfurth
Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood.
The Journal of clinical endocrinology and metabolism 2004;89(10):5003-12.
2004: Folke Lindgärde; Iréne Widén; Miriam Gebb; Bo Ahrén
Traditional versus agricultural lifestyle among Shuar women of the Ecuadorian Amazon: effects on leptin levels.
Metabolism: clinical and experimental 2004;53(10):1355-8.
2004: Shukun Yu; Jie Mei; Bo Ahrén
Basic toxicology and metabolism studies of 1,5-anhydro-D-fructose using bacteria, cultured mammalian cells, and rodents.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(10):1677-86.
2004: Eva Degerman; Vincent C Manganiello; Jens J Holst; Bo Ahrén
Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice.
European journal of pharmacology 2004;498(1-3):319-23.
2004: Ning Xu; Peter Nilsson-Ehle; Maria Hurtig; Bo Ahrén
Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo.
Biochemical and biophysical research communications 2004;321(4):916-21.
2004: Carolyn F Deacon; Bo Ahrén; Jens J Holst
Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?
Expert opinion on investigational drugs 2004;13(9):1091-102.
2004: Sophia G Moesgaard; Bo Ahrén; Richard D Carr; Dorte X Gram; Christian L Brand; Frank Sundler
Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach.
Regulatory peptides 2004;120(1-3):261-7.
2004: Maria Sörhede Winzell; Rubén Nogueiras; Carlos Dieguez; Bo Ahrén
Dual action of adiponectin on insulin secretion in insulin-resistant mice.
Biochemical and biophysical research communications 2004;321(1):154-60.
2004: Sofie Westling; Bo Ahrén; Lil Träskman-Bendz; Asa Westrin
Low CSF leptin in female suicide attempters with major depression.
Journal of affective disorders 2004;81(1):41-8.
2004: Bo Ahrén; Giovanni Pacini; David Wynick; Nils Wierup; Frank Sundler
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice.
Endocrinology 2004;145(7):3190-6.
2004: Bidda Rolin; Carolyn F Deacon; Richard D Carr; Bo Ahrén
The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice.
European journal of pharmacology 2004;494(2-3):283-8.
2004: Eva Rask; Tommy Olsson; Siv Söderberg; J j Holst Jj; A Tura; G Pacini; Bo Ahrén
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance.
Metabolism: clinical and experimental 2004;53(5):624-31.
2004: Bo Ahrén; Mona Landin-Olsson; Per-Anders Jansson; Maria Svensson; David Holmes; Anja Schweizer
Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2004;89(5):2078-84.
2004: Linda Härndahl; Nils Wierup; Sven Enerbäck; Hindrik Mulder; Vincent C Manganiello; Frank Sundler; Eva Degerman; Bo Ahrén; Lena Stenson Holst
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology.
The Journal of biological chemistry 2004;279(15):15214-22.
2004: Eva Warensjö; Jan-Håkan Jansson; Lars Berglund; Kurt Boman; Bo Ahrén; Lars Weinehall; Bernt Lindahl; Göran Hallmans; Bengt Vessby
Estimated intake of milk fat is negatively associated with cardiovascular risk factors and does not increase the risk of a first acute myocardial infarction. A prospective case-control study.
The British journal of nutrition 2004;91(4):635-42.
2004: Staffan Lindeberg; Loren Cordain; L Råstam; Bo Ahrén
Serum uric acid in traditional Pacific Islanders and in Swedes.
Journal of internal medicine 2004;255(3):373-8.
2004: Anna M Thøgersen; Siv Söderberg; Jan-Håkan Jansson; Gösta Dahlén; Kurt Boman; Torbjörn K Nilsson; Bernt Lindahl; Lars Weinehall; Hans Stenlund; Vivan Lundberg; Owe Johnson; Bo Ahrén; Göran Hallmans
Interactions between fibrinolysis, lipoproteins and leptin related to a first myocardial infarction.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2004;11(1):33-40.
2004: Bo Ahrén; Giovanni Pacini
Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies.
European journal of endocrinology / European Federation of Endocrine Societies 2004;150(2):97-104.
2004: Bo Ahrén
Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;286(2):R269-72.
2004: Folke Lindgärde; Miyaray Benavente Ercilla; Laura Retamozo Correa; Bo Ahrén
Body adiposity, insulin, and leptin in subgroups of Peruvian Amerindians.
High altitude medicine & biology 2004;5(1):27-31.
2004: Hindrik Mulder; Shumin Yang; Maria Sörhede Winzell; Cecilia Holm; Bo Ahrén
Inhibition of lipase activity and lipolysis in rat islets reduces insulin secretion.
Diabetes 2004;53(1):122-8.
2003: Lina Akesson; Bo Ahrén; Vincent C Manganiello; Lena Stenson Holst; Gudrun Edgren; Eva Degerman
Dual effects of pituitary adenylate cyclase-activating polypeptide and isoproterenol on lipid metabolism and signaling in primary rat adipocytes.
Endocrinology 2003;144(12):5293-9.
2003: Hillevi Larsson; Göran Berglund; Bo Ahrén
Insulin sensitivity, insulin secretion, and glucose tolerance versus intima-media thickness in nondiabetic postmenopausal women.
The Journal of clinical endocrinology and metabolism 2003;88(10):4791-7.
2003: Bo Ahrén; Jens J Holst; Andrea Mari
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans.
Diabetes care 2003;26(10):2860-4.
2003: Birgitta Bülow; Bo Ahrén; S Fisker; Ove Dehlin; B Hagberg; E Jensen; Torbjörn Svensson; Gillis Samuelsson; Eva Marie Erfurth
The gender differences in growth hormone-binding protein and leptin persist in 80-year-old men and women and is not caused by sex hormones.
Clinical endocrinology 2003;59(4):482-6.
2003: Bo Ahrén
Gut peptides and type 2 diabetes mellitus treatment.
Current diabetes reports 2003;3(5):365-72.
2003: Hindrik Mulder; Maria Sörhede-Winzell; Juan Antonio Contreras; Malin Fex; Kristoffer Ström; Thorkil Ploug; Henrik Galbo; Peter Arner; Cecilia Lundberg; Frank Sundler; Bo Ahrén; Cecilia Holm
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact.
The Journal of biological chemistry 2003;278(38):36380-8.
2003: Xudong Huang; Allan Vaag; Emma Carlsson; Mona Hansson; Bo Ahrén; Leif Groop
Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.
Diabetes 2003;52(9):2411-8.
2003: Bo Ahrén; Peter J Havel; G Pacini; K Cianflone
Acylation stimulating protein stimulates insulin secretion.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(9):1037-43.
2003: Bob Olsson; Mohammad Bohlooly-Y; Ola Brusehed; Olle G P Isaksson; Bo Ahrén; Sven-Olof Olofsson; Jan Oscarsson; Jan Törnell
Bovine growth hormone-transgenic mice have major alterations in hepatic expression of metabolic genes.
American journal of physiology. Endocrinology and metabolism 2003;285(3):E504-11.
2003: Maria Sörhede Winzell; Håkan Svensson; Sven Enerbäck; Kim Ravnskjaer; Susanne Mandrup; Victoria Esser; Peter Arner; Marie-Clotilde Alves-Guerra; Bruno Miroux; Frank Sundler; Bo Ahrén; Cecilia Holm
Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase.
Diabetes 2003;52(8):2057-65.
2003: Marie Guldstrand; Bo Ahrén; Regina Wredling; Lars Backman; Per-Eric Lins; Ulf Adamson
Alteration of the counterregulatory responses to insulin-induced hypoglycemia and of cognitive function after massive weight reduction in severely obese subjects.
Metabolism: clinical and experimental 2003;52(7):900-7.
2003: H Y Wong; Bo Ahrén; Cornelis J M Lips; Jo W M Höppener; F Sundler
Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
Regulatory peptides 2003;113(1-3):89-94.
2003: Guida Maria Portela-Gomes; Agneta Lukinius; Otto Ljungberg; Suad Efendic; Bo Ahrén; Samy M Abdel-Halim
PACAP is expressed in secretory granules of insulin and glucagon cells in human and rodent pancreas. Evidence for generation of cAMP compartments uncoupled from hormone release in diabetic islets.
Regulatory peptides 2003;113(1-3):31-9.
2003: Maria Sörhede Winzell; Cecilia Holm; Bo Ahrén
Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding.
Biochemical and biophysical research communications 2003;304(2):273-8.
2003: Xudong Huang; Mona Hansson; Esa Laurila; Bo Ahrén; Leif Groop
Fat feeding impairs glycogen synthase activity in mice without effects on its gene expression.
Metabolism: clinical and experimental 2003;52(5):535-9.
2003: martina kvist reimer; Sri Prakash Mokshagundam; Karen Wyler; Frank Sundler; Bo Ahrén; John I Stagner
Local growth factors are beneficial for the autonomic reinnervation of transplanted islets in rats.
Pancreas 2003;26(4):392-7.
2003: Bo Ahrén
[Reclaim the clinical research--proposal to an action plan].
Läkartidningen 2003;100(15):1361.
2003: Bo Ahrén; Ola Thorsson
Increased insulin sensitivity is associated with reduced insulin and glucagon secretion and increased insulin clearance in man.
The Journal of clinical endocrinology and metabolism 2003;88(3):1264-70.
2003: martina kvist reimer; Giovanni Pacini; Bo Ahrén
Dose-dependent inhibition by ghrelin of insulin secretion in the mouse.
Endocrinology 2003;144(3):916-21.
2003: Marie Guldstrand; Bo Ahrén; Ulf Adamson
Improved beta-cell function after standardized weight reduction in severely obese subjects.
American journal of physiology. Endocrinology and metabolism 2003;284(3):E557-65.
2003: M Abu Sayeed; Abul Kalam Azad Khan; Hajera Mahtab; Khandaker Abdul Ahsan; Akhter Banu; Parvin Akter Khanam; Bo Ahrén
Leptin is reduced in lean subjects with type 2 diabetes in bangladesh.
Diabetes care 2003;26(2):547.
2003: Staffan Lindeberg; Bo Ahrén; A Nilsson; Loren Cordain; P Nilsson-Ehle; B Vessby
Determinants of serum triglycerides and high-density lipoprotein cholesterol in traditional Trobriand Islanders: the Kitava Study.
Scandinavian journal of clinical and laboratory investigation 2003;63(3):175-80.
2003: Siv Söderberg; Birgitta Stegmayr; Christine Ahlbeck-Glader; Lisbeth Slunga-Birgander; Bo Ahrén; Tommy Olsson
High leptin levels are associated with stroke.
Cerebrovascular diseases (Basel, Switzerland) 2003;15(1-2):63-9.
2002: Jo W M Höppener; Maria G Nieuwenhuis; Thea M Vroom; Bo Ahrén; Cornelis J M Lips
Role of islet amyloid in type 2 diabetes mellitus: consequence or cause?
Molecular and cellular endocrinology 2002;197(1-2):205-12.
2002: Linda Härndahl; Xing-Jun Jing; Rosita Ivarsson; Eva Degerman; Bo Ahrén; Vincent C Manganiello; Erik Renström; Lena Stenson Holst
Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulin.
The Journal of biological chemistry 2002;277(40):37446-55.
2002: Asa Johansson; Bo Ahrén; Hakan Forsberg; Tommy Olsson
Testosterone and diurnal rhythmicity of leptin, TNF-alpha and TNF-II receptor in insulin-resistant myotonic dystrophy patients.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2002;26(10):1386-92.
2002: Kristin Persson; Giovanni Pacini; Frank Sundler; Bo Ahrén
Islet function phenotype in gastrin-releasing peptide receptor gene-deficient mice.
Endocrinology 2002;143(10):3717-26.
2002: Bo Ahrén; Giovanni Pacini
Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice.
American journal of physiology. Endocrinology and metabolism 2002;283(4):E738-44.
2002: Birgitta Bülow; Bo Ahrén
Adrenal incidentaloma--experience of a standardized diagnostic programme in the Swedish prospective study.
Journal of internal medicine 2002;252(3):239-46.
2002: Siv Söderberg; Bo Ahrén; Mats Eliasson; B Dinesen; Tommy Olsson
The association between leptin and proinsulin is lost with central obesity.
Journal of internal medicine 2002;252(2):140-8.
2002: K Persson; Bo Ahrén
The neuropeptide PACAP contributes to the glucagon response to insulin-induced hypoglycaemia in mice.
Acta physiologica Scandinavica 2002;175(1):25-8.
2002: martina kvist reimer; J J Holst; Bo Ahrén
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(5):717-27.
2002: Bo Ahrén; Erik Simonsson; Hillevi Larsson; Mona Landin-Olsson; Hlin Torgeirsson; Per-Anders Jansson; Madeléne Sandqvist; Peter Båvenholm; Suad Efendic; Jan W Eriksson; Sheila Dickinson; David Holmes
Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes.
Diabetes care 2002;25(5):869-75.
2002: Silvio Zaina; Linda Pettersson; Bo Ahrén; Lena Brånén; Andrew Bassim Hassan; Marie W Lindholm; Ragnar Mattsson; Johan Thyberg; Jan Nilsson
Insulin-like growth factor II plays a central role in atherosclerosis in a mouse model.
The Journal of biological chemistry 2002;277(6):4505-11.
2002: Martina Kvist-Reimer; Frank Sundler; Bo Ahrén
Effects of chemical sympathectomy by means of 6-hydroxydopamine on insulin secretion and islet morphology in alloxan-diabetic mice.
Cell and tissue research 2002;307(2):203-9.
2002: Bo Ahrén; Hillevi Larsson
Quantification of insulin secretion in relation to insulin sensitivity in nondiabetic postmenopausal women.
Diabetes 2002;51 Suppl 1():S202-11.
2002: martina kvist reimer; Bo Ahrén
Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice.
Diabetes 2002;51 Suppl 1():S138-43.
2002: Ville Wallenius; Kristina Wallenius; Bo Ahrén; Mats Rudling; Hans Carlsten; Suzanne Dickson; Claes Ohlsson; John-Olov Jansson
Interleukin-6-deficient mice develop mature-onset obesity.
Nature medicine 2002;8(1):75-9.
2002: Bo Ahrén; Gerald J Taborsky; Peter J Havel
Differential impairment of glucagon responses to hypoglycemia, neuroglycopenia, arginine, and carbachol in alloxan-diabetic mice.
Metabolism: clinical and experimental 2002;51(1):12-9.
2002: Sven Karlsson; Anton J W Scheurink; Bo Ahrén
Gender difference in the glucagon response to glucopenic stress in mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(1):R281-8.
2001: Birgitta Bülow; Bo Ahrén; Eva Marie Erfurth
Increased leptin and tumour necrosis factor alpha per unit fat mass in hypopituitary women without growth hormone treatment.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(6):737-42.
2001: Bo Ahrén; H Larsson
Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations.
Diabetologia 2001;44(11):1998-2003.
2001: Maria Sörhede Winzell; Håkan Svensson; Peter Arner; Bo Ahrén; Cecilia Holm
The expression of hormone-sensitive lipase in clonal beta-cells and rat islets is induced by long-term exposure to high glucose.
Diabetes 2001;50(10):2225-30.
2001: Eva Rask; Tommy Olsson; Siv Söderberg; Owe Johnson; J Seckl; Jens J Holst; Bo Ahrén
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.
Diabetes care 2001;24(9):1640-5.
2001: K Filipsson; M Kvist-Reimer; Bo Ahrén
The neuropeptide pituitary adenylate cyclase-activating polypeptide and islet function.
Diabetes 2001;50(9):1959-69.
2001: Klara Sjögren; Kristina Wallenius; Jun-Li Liu; Mohammad Bohlooly-Y; G Pacini; Lennart Svensson; Jan Törnell; Olle G P Isaksson; Bo Ahrén; John-Olov Jansson; Claes Ohlsson
Liver-derived IGF-I is of importance for normal carbohydrate and lipid metabolism.
Diabetes 2001;50(7):1539-45.
2001: Staffan Lindeberg; S Söderberg; Bo Ahrén; T Olsson
Large differences in serum leptin levels between nonwesternized and westernized populations: the Kitava study.
Journal of internal medicine 2001;249(6):553-8.
2001: Bo Ahrén; J J Holst
The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia.
Diabetes 2001;50(5):1030-8.
2001: A Guenifi; Erik Simonsson; S Karlsson; Bo Ahrén; Samy M Abdel-Halim
Carbachol restores insulin release in diabetic GK rat islets by mechanisms largely involving hydrolysis of diacylglycerol and direct interaction with the exocytotic machinery.
Pancreas 2001;22(2):164-71.
2001: S Karlsson; B Ostlund; U Myrsén-Axcrona; Frank Sundler; Bo Ahrén
Beta cell adaptation to dexamethasone-induced insulin resistance in rats involves increased glucose responsiveness but not glucose effectiveness.
Pancreas 2001;22(2):148-56.
2001: Siv Söderberg; Bo Ahrén; Mats Eliasson; B Dinesen; K Brismar; Tommy Olsson
Circulating IGF binding protein-1 is inversely associated with leptin in non-obese men and obese postmenopausal women.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(3):283-90.
2001: Folke Lindgärde; Siv Söderberg; Tommy Olsson; M B Ercilla; L R Correa; Bo Ahrén
Overweight is associated with lower serum leptin in Peruvian Indian than in Caucasian women: A dissociation contributing to low blood pressure?
Metabolism: clinical and experimental 2001;50(3):325-9.
2001: Bo Ahrén
Reducing plasma free fatty acids by acipimox improves glucose tolerance in high-fat fed mice.
Acta physiologica Scandinavica 2001;171(2):161-7.
2001: Lars Kölby; Peter Bernhardt; Håkan Ahlman; Bo Wängberg; viktor johanson; A Wigander; Eva Forssell-Aronsson; S Karlsson; Bo Ahrén; Göran Stenman; Ola Nilsson
A transplantable human carcinoid as model for somatostatin receptor-mediated and amine transporter-mediated radionuclide uptake.
The American journal of pathology 2001;158(2):745-55.
2001: S Karlsson; Frank Sundler; Bo Ahrén
Direct cytoplasmic CA(2+) responses to gastrin-releasing peptide in single beta cells.
Biochemical and biophysical research communications 2001;280(3):610-4.
2001: Siv Söderberg; Tommy Olsson; Mats Eliasson; O Johnson; K Brismar; K Carlström; Bo Ahrén
A strong association between biologically active testosterone and leptin in non-obese men and women is lost with increasing (central) adiposity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2001;25(1):98-105.
2001: A Guenifi; Bo Ahrén; Samy M Abdel-Halim
Differential effects of glucagon-like peptide-1 (7-36)amide versus cholecystokinin on arginine-induced islet hormone release in vivo and in vitro.
Pancreas 2001;22(1):58-64.
2000: Bo Ahrén; R M Baldwin; Peter J Havel
Pharmacokinetics of human leptin in mice and rhesus monkeys.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(12):1579-85.
2000: K Persson; RL Gingerich; S Nayak; K Wada; E Wada; Bo Ahrén
Reduced GLP-1 and insulin responses and glucose intolerance after gastric glucose in GRP receptor-deleted mice.
American journal of physiology. Endocrinology and metabolism 2000;279(5):E956-62.
2000: H Larsson; Folke Lindgärde; Göran Berglund; Bo Ahrén
Prediction of diabetes using ADA or WHO criteria in post-menopausal women: a 10-year follow-up study.
Diabetologia 2000;43(10):1224-8.
2000: Bo Ahrén; J J Holst; H Mårtensson; Bork Balkan
Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice.
European journal of pharmacology 2000;404(1-2):239-45.
2000: Bo Ahrén; L J Magrum; Peter J Havel; S F Greene; stephen phinney; P R Johnson; Judith S Stern
Augmented insulinotropic action of arachidonic acid through the lipoxygenase pathway in the obese Zucker rat.
Obesity research 2000;8(6):475-80.
2000: Asa Johansson; K Carlström; Bo Ahrén; Kristina Cederquist; E Krylborg; Hakan Forsberg; Tommy Olsson
Abnormal cytokine and adrenocortical hormone regulation in myotonic dystrophy.
The Journal of clinical endocrinology and metabolism 2000;85(9):3169-76.
2000: Jo W M Höppener; Bo Ahrén; Cornelis J M Lips
Islet amyloid and type 2 diabetes mellitus.
The New England journal of medicine 2000;343(6):411-9.
2000: Bo Ahrén
Diurnal variation in circulating leptin is dependent on gender, food intake and circulating insulin in mice.
Acta physiologica Scandinavica 2000;169(4):325-31.
2000: K Filipsson; JJ Holst; Bo Ahrén
PACAP contributes to insulin secretion after gastric glucose gavage in mice.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(2):R424-32.
2000: Erik Simonsson; S Karlsson; Bo Ahrén
Islet phospholipase A(2) activation is potentiated in insulin resistant mice.
Biochemical and biophysical research communications 2000;272(2):539-43.
2000: Bo Ahrén; JJ Holst; S Yu
1,5-Anhydro-D-fructose increases glucose tolerance by increasing glucagon-like peptide-1 and insulin in mice.
European journal of pharmacology 2000;397(1):219-25.
2000: Hillevi Larsson; Bo Ahrén
Islet dysfunction in insulin resistance involves impaired insulin secretion and increased glucagon secretion in postmenopausal women with impaired glucose tolerance.
Diabetes care 2000;23(5):650-7.
2000: Bo Ahrén
Autonomic regulation of islet hormone secretion--implications for health and disease.
Diabetologia 2000;43(4):393-410.
2000: H Mulder; Samuel Gebre-Medhin; C Betsholtz; Frank Sundler; Bo Ahrén
Islet amyloid polypeptide (amylin)-deficient mice develop a more severe form of alloxan-induced diabetes.
American journal of physiology. Endocrinology and metabolism 2000;278(4):E684-91.
2000: Erik Simonsson; S Karlsson; Bo Ahrén
The cyclic AMP-protein kinase A pathway restrains islet phospholipase A(2) activation.
Biochemical and biophysical research communications 2000;269(1):242-6.
2000: Bo Ahrén; JJ Holst; Suad Efendic
Antidiabetogenic action of cholecystokinin-8 in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2000;85(3):1043-8.
2000: Erik Simonsson; Bo Ahrén
Phospholipase A2 and its potential regulation of islet function.
International journal of pancreatology : official journal of the International Association of Pancreatology 2000;27(1):1-11.
2000: Hillevi Larsson; Bo Ahrén
Glucose intolerance is predicted by low insulin secretion and high glucagon secretion: outcome of a prospective study in postmenopausal Caucasian women.
Diabetologia 2000;43(2):194-202.
2000: A Johansson; Bo Ahrén; Birgitta Näsman; K Carlström; Tommy Olsson
Cortisol axis abnormalities early after stroke--relationships to cytokines and leptin.
Journal of internal medicine 2000;247(2):179-87.
2000: Sabina Janciauskiene; Bo Ahrén
Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines.
Biochemical and biophysical research communications 2000;267(2):619-25.
2000: K Filipsson; Bo Ahrén
PACAP27 sensitizes glucose induced insulin secretion in INS-1 cells.
Annals of the New York Academy of Sciences 2000;921():456-9.
2000: Bo Ahrén; K Filipsson
The effects of PACAP on insulin secretion and glucose disposal are altered by adrenalectomy in mice.
Annals of the New York Academy of Sciences 2000;921():251-8.
1999: A N al-Amin; Bo Ahrén
Relation between malnutrition and development of diabetes mellitus.
International journal of pancreatology : official journal of the International Association of Pancreatology 1999;26(3):125-30.
1999: Bo Ahrén; G Pacini
Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice.
The American journal of physiology 1999;277(6 Pt 1):E996-E1004.
1999: Siv Söderberg; Bo Ahrén; Jan-Håkan Jansson; O Johnson; Göran Hallmans; Kjell Asplund; Tommy Olsson
Leptin is associated with increased risk of myocardial infarction.
Journal of internal medicine 1999;246(4):409-18.
1999: Staffan Lindeberg; Mats Eliasson; B Lindahl; Bo Ahrén
Low serum insulin in traditional Pacific Islanders--the Kitava Study.
Metabolism: clinical and experimental 1999;48(10):1216-9.
1999: Bo Ahrén; Peter J Havel
Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells).
The American journal of physiology 1999;277(4 Pt 2):R959-66.
1999: Hillevi Larsson; Bo Ahrén
Insulin resistant subjects lack islet adaptation to short-term dexamethasone-induced reduction in insulin sensitivity.
Diabetologia 1999;42(8):936-43.
1999: H Larsson; Jens R Daugaard; Bente Kiens; Erik A Richter; Bo Ahrén
Muscle fiber characteristics in postmenopausal women with normal or impaired glucose tolerance.
Diabetes care 1999;22(8):1330-8.
1999: Bo Ahrén; P Sauerberg; C Thomsen
Increased insulin secretion and normalization of glucose tolerance by cholinergic agonism in high fat-fed mice.
The American journal of physiology 1999;277(1 Pt 1):E93-102.
1999: Bo Ahrén; Peter J Havel
Leptin increases circulating glucose, insulin and glucagon via sympathetic neural activation in fasted mice.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(6):660-5.
1999: Hillevi Larsson; Bo Ahrén
Relative hyperproinsulinemia as a sign of islet dysfunction in women with impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 1999;84(6):2068-74.
1999: O al Rayyes; Bo Ahrén; Claes-Henrik Florén
Enhancement of low density lipoprotein catabolism by non-steroidal anti-inflammatory drugs in cultured HepG2 cells.
European journal of pharmacology 1999;372(3):311-8.
1999: Siv Söderberg; Tommy Olsson; Mats Eliasson; O Johnson; Bo Ahrén
Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women.
Journal of internal medicine 1999;245(5):533-43.
1999: Jo W M Höppener; C Oosterwijk; Maria G Nieuwenhuis; George Posthuma; J H Thijssen; Thea M Vroom; Bo Ahrén; Cornelis J M Lips
Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
Diabetologia 1999;42(4):427-34.
1999: K Filipsson; F Sundler; Bo Ahrén
PACAP is an islet neuropeptide which contributes to glucose-stimulated insulin secretion.
Biochemical and biophysical research communications 1999;256(3):664-7.
1999: U Myrsén-Axcrona; Bo Ahrén; Frank Sundler
Modulatory role of adrenergic nerves on dexamethasone-induced islet cell NPY expression in the rat: evidence from chemical sympathectomy.
Pancreas 1999;18(2):180-8.
1999: Bo Ahrén
Plasma leptin and insulin in C57BI/6J mice on a high-fat diet: relation to subsequent changes in body weight.
Acta physiologica Scandinavica 1999;165(2):233-40.
1999: Siv Söderberg; Bo Ahrén; Birgitta Stegmayr; O Johnson; Per-Gunnar Wiklund; Lars Weinehall; Göran Hallmans; Tommy Olsson
Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort.
Stroke; a journal of cerebral circulation 1999;30(2):328-37.
1999: H Larsson; Bo Ahrén
Smoking habits and circulating leptin in postmenopausal non-obese women.
Diabetes, obesity & metabolism 1999;1(1):57-9.
1999: Marie Guldstrand; Lars Backman; Ulf Adamson; Per-Eric Lins; Bo Ahrén
Lowering of circulating insulin and leptin is closely associated following weight reduction after vertical banded gastroplasty in obese women.
Diabetes, obesity & metabolism 1999;1(1):53-5.
1999: S Karlsson; Bo Ahrén
Cytosolic Ca2+ oscillations by gastrin releasing peptide in single HIT-T15 cells.
Peptides 1999;20(5):579-87.
1999: Hindrik Mulder; Lena Stenson Holst; Håkan Svensson; Eva Degerman; Frank Sundler; Bo Ahrén; Patrik Rorsman; Cecilia Holm
Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells.
Diabetes 1999;48(1):228-32.
1999: Bo Ahrén; Tomas Gudbjartsson; A N Al-Amin; H Mårtensson; U Myrsén-Axcrona; S Karlsson; H Mulder; Frank Sundler
Islet perturbations in rats fed a high-fat diet.
Pancreas 1999;18(1):75-83.
1998: Bo Ahrén; K Filipsson
Pituitary adenylate cyclase activating polypeptide stimulates insulin secretion in a glucose-dependent manner in vivo.
Annals of the New York Academy of Sciences 1998;865():466-70.
1998: K Filipsson; Bo Ahrén
Protein kinase A inhibition and PACAP-induced insulin secretion in HIT-T15 cells.
Annals of the New York Academy of Sciences 1998;865():441-4.
1998: K Filipsson; S Karlsson; Bo Ahrén
Evidence for contribution by increased cytoplasmic Na+ to the insulinotropic action of PACAP38 in HIT-T15 cells.
The Journal of biological chemistry 1998;273(49):32602-7.
1998: Hillevi Larsson; S Elmståhl; Göran Berglund; Bo Ahrén
Evidence for leptin regulation of food intake in humans.
The Journal of clinical endocrinology and metabolism 1998;83(12):4382-5.
1998: S Karlsson; Frank Sundler; Bo Ahrén
CCK receptor subtype in insulin-producing cells: a combined functional and in situ hybridization study in rat islets and a rat insulinoma cell line.
Regulatory peptides 1998;78(1-3):95-103.
1998: Bo Ahrén; C Oosterwijk; Cornelis J M Lips; Jo W M Höppener
Transgenic overexpression of human islet amyloid polypeptide inhibits insulin secretion and glucose elimination after gastric glucose gavage in mice.
Diabetologia 1998;41(11):1374-80.
1998: Sabina Janciauskiene; Bo Ahrén
Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells.
Biochemical and biophysical research communications 1998;251(3):888-93.
1998: Bo Ahrén; AJ Scheurink
Marked hyperleptinemia after high-fat diet associated with severe glucose intolerance in mice.
European journal of endocrinology / European Federation of Endocrine Societies 1998;139(4):461-7.
1998: Samuel Gebre-Medhin; Hindrik Mulder; Milos Pekny; Gunilla T Westermark; Jan Törnell; Per Westermark; Frank Sundler; Bo Ahrén; Christer Betsholtz
Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin).
Biochemical and biophysical research communications 1998;250(2):271-7.
1998: Lena Stenson Holst; Hindrik Mulder; Vincent C Manganiello; Frank Sundler; Bo Ahrén; Cecilia Holm; Eva Degerman
Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I.
Biochemical and biophysical research communications 1998;250(1):181-6.
1998: Bo Ahrén; G Pacini
Age-related reduction in glucose elimination is accompanied by reduced glucose effectiveness and increased hepatic insulin extraction in man.
The Journal of clinical endocrinology and metabolism 1998;83(9):3350-6.
1998: Erik Simonsson; S Karlsson; Bo Ahrén
Ca2+-independent phospholipase A2 contributes to the insulinotropic action of cholecystokinin-8 in rat islets: dissociation from the mechanism of carbachol.
Diabetes 1998;47(9):1436-43.
1998: Bo Ahrén
Glucagon-like peptide-1 (GLP-1): a gut hormone of potential interest in the treatment of diabetes.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(8):642-51.
1998: Hillevi Larsson; Bo Ahrén
Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine.
Diabetologia 1998;41(7):772-7.
1998: K Filipsson; Frank Sundler; Jens Hannibal; Bo Ahrén
PACAP and PACAP receptors in insulin producing tissues: localization and effects.
Regulatory peptides 1998;74(2-3):167-75.
1998: Erik Simonsson; Bo Ahrén
Potentiated beta-cell response to non-glucose stimuli in insulin-resistant C57BL/6J mice.
European journal of pharmacology 1998;350(2-3):243-50.
1998: K Filipsson; G Pacini; AJ Scheurink; Bo Ahrén
PACAP stimulates insulin secretion but inhibits insulin sensitivity in mice.
The American journal of physiology 1998;274(5 Pt 1):E834-42.
1998: S Lindskog; K Hermansen; Bo Ahrén
Effect of 3-O-methylglucose on insulin secretion in the perfused dog and rat pancreas.
Pancreas 1998;16(4):511-4.
1998: Claes-Henrik Florén; Bo Ahrén; M Bengtsson; J Bartosik; Karl Obrant
Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine.
Journal of internal medicine 1998;243(2):123-6.
1998: S Karlsson; Bo Ahrén
Insulin and glucagon secretion by ganglionic nicotinic activation in adrenalectomized mice.
European journal of pharmacology 1998;342(2-3):291-5.
1998: S Karlsson; Frank Sundler; Bo Ahrén
Insulin secretion by gastrin-releasing peptide in mice: ganglionic versus direct islet effect.
The American journal of physiology 1998;274(1 Pt 1):E124-9.
1997: Bo Ahrén; H Larsson
Leptin--a regulator of islet function?: its plasma levels correlate with glucagon and insulin secretion in healthy women.
Metabolism: clinical and experimental 1997;46(12):1477-81.
1997: Bo Ahrén; M Gutniak
No correlation between insulin and islet amyloid polypeptide after stimulation with glucagon-like peptide-1 in type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(6):643-9.
1997: Bo Ahrén; G Pacini
Impaired adaptation of first-phase insulin secretion in postmenopausal women with glucose intolerance.
The American journal of physiology 1997;273(4 Pt 1):E701-7.
1997: K Filipsson; K Tornøe; JJ Holst; Bo Ahrén
Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.
The Journal of clinical endocrinology and metabolism 1997;82(9):3093-8.
1997: Hillevi Larsson; JJ Holst; Bo Ahrén
Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans.
Acta physiologica Scandinavica 1997;160(4):413-22.
1997: Bo Ahrén; Hillevi Larsson; JJ Holst
Reduced gastric inhibitory polypeptide but normal glucagon-like peptide 1 response to oral glucose in postmenopausal women with impaired glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(2):127-31.
1997: Sabina Janciauskiene; S Eriksson; E Carlemalm; Bo Ahrén
B cell granule peptides affect human islet amyloid polypeptide (IAPP) fibril formation in vitro.
Biochemical and biophysical research communications 1997;236(3):580-5.
1997: Bo Ahrén; Sven Månsson; RL Gingerich; Peter J Havel
Regulation of plasma leptin in mice: influence of age, high-fat diet, and fasting.
The American journal of physiology 1997;273(1 Pt 2):R113-20.
1997: Bo Ahrén; Hillevi Larsson; JJ Holst
Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in noninsulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1997;82(2):473-8.
1997: Bo Ahrén; Erik Simonsson; AJ Scheurink; H Mulder; U Myrsén; Frank Sundler
Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice.
Metabolism: clinical and experimental 1997;46(1):97-106.
1996: K af Klinteberg; S Karlsson; K Moller; Frank Sundler; Bo Ahrén
Pituitary adenylate cyclase-activating polypeptide (PACAP) and insulin secretion: effects and mechanisms.
Annals of the New York Academy of Sciences 1996;805():543-8.
1996: Bo Ahrén; Hillevi Larsson
Plasma neuropeptide Y in impaired glucose tolerance.
Acta diabetologica 1996;33(4):295-7.
1996: Hillevi Larsson; Bo Ahrén
Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women.
The Journal of clinical endocrinology and metabolism 1996;81(12):4428-32.
1996: Hillevi Larsson; Bo Ahrén
Androgen activity as a risk factor for impaired glucose tolerance in postmenopausal women.
Diabetes care 1996;19(12):1399-403.
1996: Hillevi Larsson; Sölve Elmståhl; Bo Ahrén
Plasma leptin levels correlate to islet function independently of body fat in postmenopausal women.
Diabetes 1996;45(11):1580-4.
1996: U Myrsén; Bo Ahrén; F Sundler
Dexamethasone-induced neuropeptide Y expression in rat islet endocrine cells. Rapid reversibility and partial prevention by insulin.
Diabetes 1996;45(10):1306-16.
1996: Erik Simonsson; S Karlsson; Bo Ahrén
Involvement of phospholipase A2 and arachidonic acid in cholecystokinin-8-induced insulin secretion in rat islets.
Regulatory peptides 1996;65(2):101-7.
1996: Hillevi Larsson; Bo Ahrén
Failure to adequately adapt reduced insulin sensitivity with increased insulin secretion in women with impaired glucose tolerance.
Diabetologia 1996;39(9):1099-107.
1996: Bo Ahrén; GYSLAINE BERTRAND; M Roye; G Ribes
Pancreastatin modulates glucose-stimulated insulin secretion from the perfused rat pancreas.
Acta physiologica Scandinavica 1996;158(1):63-70.
1996: Bo Ahrén; Erik Simonsson; S Karlsson
Glucagon-like peptide-1(7-36)amide and cytoplasmic calcium in insulin producing cells.
Acta physiologica Scandinavica 1996;157(3):333-41.
1996: K A Klinteberg; S Karlsson; Bo Ahrén
Signaling mechanisms underlying the insulinotropic effect of pituitary adenylate cyclase-activating polypeptide in HIT-T15 cells.
Endocrinology 1996;137(7):2791-8.
1996: B G Leifsson; Bo Ahrén
Serum calcium and survival in a large health screening program.
The Journal of clinical endocrinology and metabolism 1996;81(6):2149-53.
1996: S Karlsson; Bo Ahrén
A role for islet peptide YY in the regulation of insulin secretion.
Acta physiologica Scandinavica 1996;157(2):305-6.
1996: Bo Ahrén
Galanin increases cytoplasmic calcium in insulin-producing RINm5F cells by activating phospholipase C.
Biochemical and biophysical research communications 1996;221(1):89-94.
1996: Bo Ahrén; Göran Sundkvist; H Mulder; Frank Sundler
Blockade of muscarinic transmission increases the frequency of diabetes after low-dose alloxan challenge in the mouse.
Diabetologia 1996;39(4):383-90.
1996: H Larsson; Bo Ahrén
Islet dysfunction in obese women with impaired glucose tolerance.
Metabolism: clinical and experimental 1996;45(4):502-9.
1996: S Gregersen; Bo Ahrén
Studies on the mechanisms by which gastrin releasing peptide potentiates glucose-induced insulin secretion from mouse islets.
Pancreas 1996;12(1):48-57.
1996: S Karlsson; Bo Ahrén
Gastrin-releasing peptide mobilizes calcium from intracellular stores in HIT-T15 cells.
Peptides 1996;17(6):909-16.
1995: Bo Ahrén; RL Gingerich; Peter J Havel
Effects of cholecystokinin and glucagon-like peptide 1 on the secretion of pancreatic polypeptide in mice.
Regulatory peptides 1995;59(3):297-302.
1995: Bo Ahrén; Judith S Stern; RL Gingerich; D L Curry; Peter J Havel
Glucagon secretory response to hypoglycaemia, adrenaline and carbachol in streptozotocin-diabetic rats.
Acta physiologica Scandinavica 1995;155(2):215-21.
1995: S Lindskog; S Gregersen; K Hermansen; Bo Ahrén
Effects of galanin on proinsulin mRNA and insulin biosynthesis in normal islets.
Regulatory peptides 1995;58(3):135-9.
1995: Bo Ahrén; S Lindskog; Gertjan van Dijk; Anton J W Scheurink; AB Steffens
Effects of GLP-1 and 2,5-anhydro-D-mannitol on insulin secretion and plasma glucose in mice.
Endocrine research 1995;21(3):583-94.
1995: H Larsson; Bo Ahrén
Effects of arginine on the secretion of insulin and islet amyloid polypeptide in humans.
Pancreas 1995;11(2):201-5.
1995: Bo Ahrén; S Karlsson; Anton J W Scheurink; AB Steffens
Involvement of nitric oxide in neuroglycopenia-induced insulin and glucagon secretion in the mouse.
European journal of pharmacology 1995;280(1):27-35.
1995: Hillevi Larsson; G Berglund; Bo Ahrén
Glucose modulation of insulin and glucagon secretion is altered in impaired glucose tolerance.
The Journal of clinical endocrinology and metabolism 1995;80(6):1778-82.
1995: Bo Ahrén
Antidiabetogenic action of truncated glucagon-like peptide-1 in mice.
Endocrine 1995;3(5):367-9.
1995: Bo Ahrén; Göran Sundkvist
Long-term effects of alloxan in mice.
International journal of pancreatology : official journal of the International Association of Pancreatology 1995;17(2):197-201.
1995: Bo Ahrén
Insulinotropic action of truncated glucagon-like peptide-1 in mice.
Acta physiologica Scandinavica 1995;153(2):205-6.
1995: Bo Ahrén; A Bergenfelz
Effects of minor increase in serum calcium on the immunoheterogeneity of parathyroid hormone in healthy subjects and in patients with primary hyperparathyroidism.
Hormone research 1995;43(6):294-9.
1994: S Karlsson; Anton J W Scheurink; AB Steffens; Bo Ahrén
Involvement of capsaicin-sensitive nerves in regulation of insulin secretion and glucose tolerance in conscious mice.
The American journal of physiology 1994;267(4 Pt 2):R1071-7.
1994: A G Nieuwenhuizen; S Karlsson; T Fridolf; Bo Ahrén
Mechanisms underlying the insulinostatic effect of peptide YY in mouse pancreatic islets.
Diabetologia 1994;37(9):871-8.
1994: S Gregersen; Ulo Langel; Tamas Bartfai; Bo Ahrén
N-terminally elongated fragments of galanin(1-16) inhibit insulin secretion from isolated mouse islets.
Regulatory peptides 1994;53(1):31-7.
1994: S Gregersen; Ulo Langel; Tamas Bartfai; Bo Ahrén
Galanin message-associated polypeptide (GMAP) does not affect insulin secretion from isolated islets.
European journal of pharmacology 1994;259(1):79-82.
1993: Tamas Bartfai; Ulo Langel; K Bedecs; S Andell; T Land; S Gregersen; Bo Ahrén; P Girotti; S Consolo; R Corwin
Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11287-91.
1993: T Fridolf; Bo Ahrén
Effects of glucagon like peptide-1(7-36) amide on the cytoplasmic Ca(2+)-concentration in rat islet cells.
Molecular and cellular endocrinology 1993;96(1-2):85-90.
1993: T Fridolf; S Karlsson; Bo Ahrén
Role of extracellular Na+ on CCK-8-induced insulin secretion.
Biochemical and biophysical research communications 1993;192(3):1162-8.
1993: T Fridolf; Bo Ahrén
Dual action of the neuropeptide galanin on the cytoplasmic free calcium concentration in RIN m5F cells.
Biochemical and biophysical research communications 1993;191(3):1224-9.
1993: S Gregersen; S Lindskog; T Land; Ulo Langel; Tamas Bartfai; Bo Ahrén
Blockade of galanin-induced inhibition of insulin secretion from isolated mouse islets by the non-methionine containing antagonist M35.
European journal of pharmacology 1993;232(1):35-9.
1992: Anders Bergenfelz; C Lundstedt; H Stridbeck; Bo Ahrén
Large vein sampling for intact parathyroid hormone in preoperative localization of enlarged parathyroid glands.
Acta radiologica (Stockholm, Sweden : 1987) 1992;33(6):528-31.
1992: S Karlsson; Bo Ahrén
Effects of tacrine on insulin secretion and 86Rb+ and 45Ca++ efflux from rat pancreatic islets.
The Journal of pharmacology and experimental therapeutics 1992;263(2):494-8.
1992: T Fridolf; F Sundler; Bo Ahrén
Pituitary adenylate cyclase-activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse.
Cell and tissue research 1992;269(2):275-9.
1992: Anders Bergenfelz; Jan Tennvall; Bo Ahrén
Thallium-technetium subtraction scintigraphy of enlarged parathyroid glands after calcitonin stimulation of parathyroid hormone secretion.
Acta radiologica (Stockholm, Sweden : 1987) 1992;33(4):319-22.
1992: S Karlsson; F Sundler; Bo Ahrén
Neonatal capsaicin-treatment in mice: effects on pancreatic peptidergic nerves and 2-deoxy-D-glucose-induced insulin and glucagon secretion.
Journal of the autonomic nervous system 1992;39(1):51-9.
1992: T Fridolf; S Karlsson; Bo Ahrén
Effects of CCK-8 on the cytoplasmic free calcium concentration in isolated rat islet cells.
Biochemical and biophysical research communications 1992;184(2):878-82.
1992: S Karlsson; Bo Ahrén
CCK-8-stimulated insulin secretion in vivo is mediated by CCKA receptors.
European journal of pharmacology 1992;213(1):145-6.
1992: S Lindskog; G Skoglund; Bo Ahrén
Pancreastatin inhibits insulin secretion from isolated rat islets: studies on its mechanism of action.
Diabetes research (Edinburgh, Scotland) 1992;19(3):119-23.
1992: Bo Ahrén; H Gregersen; M S Amiri; S L Jensen
Galanin inhibits tolbutamide-stimulated insulin secretion in the perfused pig pancreas.
Diabetes research (Edinburgh, Scotland) 1992;19(2):59-62.
1992: S Lindskog; Bo Ahrén; T Land; Ulo Langel; Tamas Bartfai
The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion.
European journal of pharmacology 1992;210(2):183-8.
1992: Bo Ahrén; C G Ostenson; S Efendic
The intestinal peptide PEC-60 inhibits insulin secretion in the mouse and the rat.
Pancreas 1992;7(4):443-6.
1992: S Lindskog; Bo Ahrén
Effects of galanin and norepinephrine on insulin secretion in the mouse.
Pancreas 1992;7(6):636-41.
1991: S Lindskog; Bo Ahrén
Studies on the mechanism by which galanin inhibits insulin secretion in islets.
European journal of pharmacology 1991;205(1):21-7.
1991: S Karlsson; Bo Ahrén
Contribution of adrenergic nerves and the adrenals to 2-deoxy-D-glucose-induced insulin and glucagon secretion in the mouse.
International journal of pancreatology : official journal of the International Association of Pancreatology 1991;10(3-4):207-15.
1991: S Gregersen; K Hermansen; Ulo Langel; G Fisone; Tamas Bartfai; Bo Ahrén
Galanin-induced inhibition of insulin secretion from rat islets: effects of rat and pig galanin and galanin fragments and analogues.
European journal of pharmacology 1991;203(1):111-4.
1991: S Karlsson; Bo Ahrén
CCKA receptor antagonism inhibits mechanisms underlying CCK-8-stimulated insulin release in isolated rat islets.
European journal of pharmacology 1991;202(2):253-7.
1991: Anders Bergenfelz; L Forsberg; E Hederström; Bo Ahrén
Preoperative localization of enlarged parathyroid glands with ultrasonically guided fine needle aspiration for parathyroid hormone assay.
Acta radiologica (Stockholm, Sweden : 1987) 1991;32(5):403-5.
1991: Bo Ahrén; M Pettersson; K Uvnäs-Moberg; M Gutniak; S Efendic
Effects of cholecystokinin (CCK)-8, CCK-33, and gastric inhibitory polypeptide (GIP) on basal and meal-stimulated pancreatic hormone secretion in man.
Diabetes research and clinical practice 1991;13(3):153-61.
1991: S Sjövall; A Foss; R Audisio; Bo Ahrén; S Bengmark
Mitomycin C and lipiodol do not improve the effect of intermittent hepatic artery occlusion on liver tumour growth. An experimental study in the rat.
Anticancer research 1991;11(5):1823-5.
1991: T Fridolf; Bo Ahrén
GLP-1(7-36)amide-stimulated insulin secretion in rat islets is sodium-dependent.
Biochemical and biophysical research communications 1991;179(1):701-6.
1991: S Karlsson; Bo Ahrén
Cholecystokinin-stimulated insulin secretion and protein kinase C in rat pancreatic islets.
Acta physiologica Scandinavica 1991;142(3):397-403.
1991: Bo Ahrén; C G Ostenson; H Mårtensson; S Efendic
Pancreatic release of pancreastatin in the pig.
Pancreas 1991;6(3):324-9.
1991: Bo Ahrén; A Ar'Rajab; G Böttcher; F Sundler; B E Dunning
Presence of galanin in human pancreatic nerves and inhibition of insulin secretion from isolated human islets.
Cell and tissue research 1991;264(2):263-7.
1991: S Sjövall; Bo Ahrén
Hepatic dearterialisation induces glucose intolerance and inhibits insulin secretion in patients with liver malignancy.
The European journal of surgery = Acta chirurgica 1991;157(5):329-32.
1991: T Fridolf; Bo Ahrén
GLP-1(7-36) amide stimulates insulin secretion in rat islets: studies on the mode of action.
Diabetes research (Edinburgh, Scotland) 1991;16(4):185-91.
1991: T Fridolf; G Böttcher; F Sundler; Bo Ahrén
GLP-1 and GLP-1(7-36) amide: influences on basal and stimulated insulin and glucagon secretion in the mouse.
Pancreas 1991;6(2):208-15.
1991: S Karlsson; Bo Ahrén
Dependence on extracellular Ca2+ for the effects of cholecystokinin-8 in rat pancreatic islets.
Diabetes research (Edinburgh, Scotland) 1991;16(3):139-43.
1991: Bo Ahrén; Per-Olof Berggren; P Rorsman; C G Ostenson; S Efendic
Neuropeptides in the regulation of islet hormone secretion--localization, effects and mode of action.
Advances in experimental medicine and biology 1991;291():129-42.
1990: M Pettersson; Bo Ahrén
Calcitonin gene-related peptide inhibits insulin secretion studies on ion fluxes and cyclic AMP in isolated rat islets.
Diabetes research (Edinburgh, Scotland) 1990;15(1):9-14.
1990: Bo Ahrén; G Böttcher; S Kowalyk; B E Dunning; F Sundler; Gerald J Taborsky
Galanin is co-localized with noradrenaline and neuropeptide Y in dog pancreas and celiac ganglion.
Cell and tissue research 1990;261(1):49-58.
1990: Bo Ahrén; Stefan G Pierzynowski; Björn Weström; B Karlsson
Pancreastatin inhibits insulin secretion and exocrine pancreatic secretion in the pig.
Diabetes research (Edinburgh, Scotland) 1990;14(2):93-6.
1990: Bo Ahrén; M Pettersson
Calcitonin gene-related peptide (CGRP) and amylin and the endocrine pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1990;6(1):1-15.
1990: Bo Ahrén; S Karlsson; S Lindskog
Cholinergic regulation of the endocrine pancreas.
Progress in brain research 1990;84():209-18.
1989: Bo Ahrén
Effects of beta-endorphin, met-enkephalin, and dynorphin A on basal and stimulated insulin secretion in the mouse.
International journal of pancreatology : official journal of the International Association of Pancreatology 1989;5(2):165-78.
1989: Bo Ahrén; G Skoglund
Insulin secretion in neonatally streptozotocin-injected mice.
Diabetes research (Edinburgh, Scotland) 1989;11(4):185-9.
1989: Bo Ahrén; R Ekman; P Laurberg
Calcium stimulates the release of calcitonin gene-related peptide from the canine thyroid.
The American journal of physiology 1989;256(5 Pt 1):E597-9.
1989: Bo Ahrén
Helodermin stimulates glucagon secretion in the mouse.
Peptides 1989;10(3):709-11.
1989: Bo Ahrén; G Böttcher; R Ekman; F Sundler
Cysteamine and the endocrine pancreas: immunocytochemical, immunochemical, and functional aspects.
Cell and tissue research 1989;256(1):159-66.
1989: S Lindskog; Bo Ahrén
Effects of galanin on insulin and glucagon secretion in the rat.
International journal of pancreatology : official journal of the International Association of Pancreatology 1989;4(3):335-44.
1989: S Karlsson; Bo Ahrén
Effects of three different cholecystokinin receptor antagonists on basal and stimulated insulin and glucagon secretion in mice.
Acta physiologica Scandinavica 1989;135(3):271-8.
1989: Bo Ahrén
Effects of gastrin-releasing peptide on basal and stimulated thyroid hormone secretion in the mouse.
Acta endocrinologica 1989;120(2):245-9.
1989: Bo Ahrén
Effects of calcitonin, katacalcin, and calcitonin gene-related peptide on basal and TSH-stimulated thyroid hormone secretion in the mouse.
Acta physiologica Scandinavica 1989;135(2):133-7.
1989: G Skoglund; Bo Ahrén; I Lundquist
Insulin secretion and islet lysosomal enzyme activities in the mouse. Effects of suramin.
International journal of pancreatology : official journal of the International Association of Pancreatology 1989;4(1):29-40.
1988: G Skoglund; Bo Ahrén; I Lundquist
Islet hormone secretion and islet lysosomal enzyme activities in the mouse: effects of chloroquine.
Diabetes research (Edinburgh, Scotland) 1988;9(3):145-9.
1988: Bo Ahrén
ANF inhibits glucose-stimulated insulin secretion in mouse and rat.
The American journal of physiology 1988;255(5 Pt 1):E579-82.
1988: M Pettersson; Bo Ahrén
Insulin and glucagon secretion in the rat: effects of gastrin releasing peptide.
Neuropeptides 1988;12(3):159-63.
1988: Bo Ahrén; R C Veith; G J Taborsky
The effects of epinephrine on islet hormone secretion in the dog.
International journal of pancreatology : official journal of the International Association of Pancreatology 1988;3(5):375-88.
1988: Bo Ahrén; P Rorsman; Per-Olof Berggren
Galanin and the endocrine pancreas.
FEBS letters 1988;229(2):233-7.
1988: Bo Ahrén; Gerald J Taborsky
Effects of pancreatic noradrenaline infusion on basal and stimulated islet hormone secretion in the dog.
Acta physiologica Scandinavica 1988;132(2):143-50.
1988: S Karlsson; Bo Ahrén
Effects of corticotropin-releasing hormone on insulin and glucagon secretion in mice.
Acta endocrinologica 1988;117(1):87-92.
1988: S Lindskog; Bo Ahrén
Galanin and pancreastatin inhibit stimulated insulin secretion in the mouse: comparison of effects.
Hormone research 1988;29(5-6):237-40.
1987: G Skoglund; I Lundquist; Bo Ahrén
Alpha 1- and alpha 2-adrenoceptor activation increases plasma glucagon levels in the mouse.
European journal of pharmacology 1987;143(1):83-8.
1987: M Pettersson; I Lundquist; Bo Ahrén
Neuropeptide Y and calcitonin gene-related peptide: effects on glucagon and insulin secretion in the mouse.
Endocrine research 1987;13(4):407-17.