FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jan-Olof Svensson

Research Profile

Procedures

High Pressure Liquid Chromatography

Chemicals & Drugs

Concepts & Ideas

Physiology

Living Beings

European Continental Ancestry Group

Phenomena

Hydroxylation

Co-author Network

Publications

TOP 3
Jackson K Mukonzo; Daniel Röshammar; paul waako; Maria Andersson; Takashi Fukasawa; Lili Milani; Jan-Olof Svensson; Jasper Ogwal-Okeng; Lars ´Gustafsson; Eleni Aklillu
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
Mats Gåfvels; Petra Holmström; Anna Somell; Fredrik Sjövall; Jan-Olof Svensson; Lars Ståhle; Ulrika Broomé; Per Stål
A novel mutation in the biliverdin reductase-A gene combined with liver cirrhosis results in hyperbiliverdinaemia (green jaundice).
Synnove Lindemalm; Per Nydert; Jan-Olof Svensson; Lars Stahle; Ihsan Sarman
Transfer of buprenorphine into breast milk and calculation of infant drug dose.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jan-Olof Svensson (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2009: Jackson K Mukonzo; Daniel Röshammar; paul waako; Maria Andersson; Takashi Fukasawa; Lili Milani; Jan-Olof Svensson; Jasper Ogwal-Okeng; Lars ´Gustafsson; Eleni Aklillu
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
British journal of clinical pharmacology 2009;68(5):690-9.
2009: Mats Gåfvels; Petra Holmström; Anna Somell; Fredrik Sjövall; Jan-Olof Svensson; Lars Ståhle; Ulrika Broomé; Per Stål
A novel mutation in the biliverdin reductase-A gene combined with liver cirrhosis results in hyperbiliverdinaemia (green jaundice).
Liver international : official journal of the International Association for the Study of the Liver 2009;29(7):1116-24.
2009: Synnove Lindemalm; Per Nydert; Jan-Olof Svensson; Lars Stahle; Ihsan Sarman
Transfer of buprenorphine into breast milk and calculation of infant drug dose.
Journal of human lactation : official journal of International Lactation Consultant Association 2009;25(2):199-205.
2007: Vural Ozdemir; Leif Bertilsson; Jun Miura; Erin Carpenter; Christopher Reist; Patricia Harper; Jolanta Widén; Jan-Olof Svensson; Lawrence J Albers; James L Kennedy; Laszlo Endrenyi; Werner Kalow
CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonin-dopamine crosstalk revisited.
Pharmacogenetics and genomics 2007;17(5):339-47.
2006: Anders Helldén; Jan Lycke; Tatiana Vander; Jan-Olof Svensson; Ingegerd Odar-Cederlöf; Lars Ståhle
The aciclovir metabolite CMMG is detectable in the CSF of subjects with neuropsychiatric symptoms during aciclovir and valaciclovir treatment.
The Journal of antimicrobial chemotherapy 2006;57(5):945-9.
2006: Aylin Yilmaz; Dietmar Fuchs; Lars Hagberg; Ulrika Nillroth; Lars Ståhle; Jan-Olof Svensson; Magnus Gisslen
Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study.
BMC infectious diseases 2006;6():63.
2005: Umit Yasar; Anita Annas; Jan-Olof Svensson; Lucia Lazorova; P Artursson; Ayman Al-Shurbaji
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein.
Xenobiotica; the fate of foreign compounds in biological systems 2005;35(8):785-96.
2005: Agneta Wennerholm; Annika Allqvist; Jan-Olof Svensson; Lars ´Gustafsson; Rajaa A Mirghani; Leif Bertilsson
Alprazolam as a probe for CYP3A using a single blood sample: pharmacokinetics of parent drug, and of alpha- and 4-hydroxy metabolites in healthy subjects.
European journal of clinical pharmacology 2005;61(2):113-8.
2005: Annika Allqvist; Agneta Wennerholm; Jan-Olof Svensson; Rajaa A Mirghani
Simultaneous quantification of alprazolam, 4- and alpha-hydroxyalprazolam in plasma samples using liquid chromatography mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;814(1):127-31.
2004: Mike Ufer; Bernd Kammerer; Julia Kirchheiner; Anders Rane; Jan-Olof Svensson
Determination of phenprocoumon, warfarin and their monohydroxylated metabolites in human plasma and urine by liquid chromatography-mass spectrometry after solid-phase extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;809(2):217-26.
2004: Lars Ståhle; Lars Moberg; Jan-Olof Svensson; Anders Sönnerborg
Efavirenz plasma concentrations in HIV-infected patients: inter- and intraindividual variability and clinical effects.
Therapeutic drug monitoring 2004;26(3):267-70.
2004: Aleksandra Bulka; Poli Francois Kouya; Ylva Böttiger; Jan-Olof Svensson; Xiao-Jun Xu; Zsuzsanna Wiesenfeld-Hallin
Comparison of the antinociceptive effect of morphine, methadone, buprenorphine and codeine in two substrains of Sprague-Dawley rats.
European journal of pharmacology 2004;492(1):27-34.
2004: Mike Ufer; Jan-Olof Svensson; Kristopher W Krausz; Harry V Gelboin; Anders Rane; Gunnel Tybring
Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro.
European journal of clinical pharmacology 2004;60(3):173-82.
2003: Mia von Euler; Tomas Villén; Jan-Olof Svensson; Lars Ståhle
Interpretation of the presence of 6-monoacetylmorphine in the absence of morphine-3-glucuronide in urine samples: evidence of heroin abuse.
Therapeutic drug monitoring 2003;25(5):645-8.
2003: Anders Helldén; Ingegerd Odar-Cederlöf; Per Diener; Lisbeth Barkholt; Charlotte Medin; Jan-Olof Svensson; Juliette Säwe; Lars Ståhle
High serum concentrations of the acyclovir main metabolite 9-carboxymethoxymethylguanine in renal failure patients with acyclovir-related neuropsychiatric side effects: an observational study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(6):1135-41.
2003: O M S Minzi; M Rais; Jan-Olof Svensson; Lars ´Gustafsson; Orjan Ericsson
High-performance liquid chromatographic method for determination of amodiaquine, chloroquine and their monodesethyl metabolites in biological samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;783(2):473-80.
2002: Peeter Jaanson; Toomas Marandi; Raul-Allan Kiivet; Veiko Vasar; Siiri Vään; Jan-Olof Svensson; Marja-Liisa Dahl
Maintenance therapy with zuclopenthixol decanoate: associations between plasma concentrations, neurological side effects and CYP2D6 genotype.
Psychopharmacology 2002;162(1):67-73.
2002: J Persson; Jan Hasselström; A Maurset; I Oye; Jan-Olof Svensson; O Almqvist; H Scheinin; Lars ´Gustafsson; O Almqvist
Pharmacokinetics and non-analgesic effects of S- and R-ketamines in healthy volunteers with normal and reduced metabolic capacity.
European journal of clinical pharmacology 2002;57(12):869-75.
2002: Agneta Wennerholm; Collet Dandara; Jane Sayi; Jan-Olof Svensson; Yakoub Aden Abdi; Magnus Ingelman-Sundberg; Leif Bertilsson; Julia A Hasler; Lars ´Gustafsson
The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity.
Clinical pharmacology and therapeutics 2002;71(1):77-88.
2001: Hyung-Keun Roh; C E Kim; Woon-Gye Chung; C S Park; Jan-Olof Svensson; Leif Bertilsson
Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients.
European journal of clinical pharmacology 2001;57(9):671-5.
2001: Kari Laine; Gunnel Tybring; Sebastian Härtter; K Andersson; Jan-Olof Svensson; Jolanta Widén; Leif Bertilsson
Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test.
Clinical pharmacology and therapeutics 2001;70(4):327-35.
2001: Hyung-Keun Roh; J Y Chung; D Y Oh; C S Park; Jan-Olof Svensson; Marja-Liisa Dahl; Leif Bertilsson
Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients.
British journal of clinical pharmacology 2001;52(3):265-71.
2001: Jan-Olof Svensson; Juliette Säwe; Ayman Al-Shurbaji
Determination of ketobemidone and its metabolites in plasma and urine using solid-phase extraction and liquid chromatography-mass spectrometry.
Therapeutic drug monitoring 2001;23(4):399-405.
2001: K Bodin; Jan-Olof Svensson
Determination of LSD in urine with high-performance liquid chromatography--mass spectrometry.
Therapeutic drug monitoring 2001;23(4):389-93.
2000: Jan-Olof Svensson; Anders Sönnerborg; Lars Ståhle
Rapid and simple determination of indinavir in serum, urine, and cerebrospinal fluid using high-performance liquid chromatography.
Therapeutic drug monitoring 2000;22(5):626-9.
2000: Moustapha Hassan; Jan-Olof Svensson; Christina Nilsson; Patrik Hentschke; Ayman Al-Shurbaji; Johan Aschan; Per Ljungman; Olle Ringdén
Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy.
Therapeutic drug monitoring 2000;22(4):383-5.
2000: Jan-Olof Svensson; Annette Bruchfeld; Robert Schvarcz; Lars Ståhle
Determination of ribavirin in serum using highly selective solid-phase extraction and high-performance liquid chromatography.
Therapeutic drug monitoring 2000;22(2):215-8.
1999: Jan-Olof Svensson; Leif Bertilsson
Rapid high-performance liquid chromatographic method for determination of debrisoquine and 4-hydroxy-debrisoquine in urine for CYP2D6 phenotyping.
Pharmacogenetics 1999;9(4):529-31.
1999: C Martin; Anders Sönnerborg; Jan-Olof Svensson; Lars Ståhle
Indinavir-based treatment of HIV-1 infected patients: efficacy in the central nervous system.
AIDS (London, England) 1999;13(10):1227-32.
1999: Jan-Olof Svensson; Christina Brattström; Juliette Säwe
A simple HPLC method for simultaneous determination of mycophenolic acid and mycophenolic acid glucuronide in plasma.
Therapeutic drug monitoring 1999;21(3):322-4.
1999: Ylva Böttiger; Jan-Olof Svensson; Lars Ståhle
Lamotrigine drug interactions in a TDM material.
Therapeutic drug monitoring 1999;21(2):171-4.
1999: QY Yue; Jan Hasselström; Jan-Olof Svensson; Juliette Säwe
Effect of codeine on oro-cecal transit time in Chinese healthy volunteers in comparison with Caucasian subjects.
European journal of clinical pharmacology 1999;54(11):839-42.
1998: J Persson; Jan Hasselström; B Wiklund; A Heller; Jan-Olof Svensson; Lars ´Gustafsson
The analgesic effect of racemic ketamine in patients with chronic ischemic pain due to lower extremity arteriosclerosis obliterans.
Acta anaesthesiologica Scandinavica 1998;42(7):750-8.
1997: Lars Ståhle; C Martin; Jan-Olof Svensson; Anders Sönnerborg
Indinavir in cerebrospinal fluid of HIV-1-infected patients.
Lancet 1997;350(9094):1823.
1997: QY Yue; C Alm; Jan-Olof Svensson; Juliette Säwe
Quantification of the O- and N-demethylated and the glucuronidated metabolites of codeine relative to the debrisoquine metabolic ratio in urine in ultrarapid, rapid, and poor debrisoquine hydroxylators.
Therapeutic drug monitoring 1997;19(5):539-42.
1997: N Yasui; Gunnel Tybring; Koichi Otani; Kazuo Mihara; Akihito Suzuki; Jan-Olof Svensson; Sunao Kaneko
Effects of thioridazine, an inhibitor of CYP2D6, on the steady-state plasma concentrations of the enantiomers of mianserin and its active metabolite, desmethylmianserin, in depressed Japanese patients.
Pharmacogenetics 1997;7(5):369-74.
1997: Jan-Olof Svensson; Lisbeth Barkholt; Juliette Säwe
Determination of acyclovir and its metabolite 9-carboxymethoxymethylguanine in serum and urine using solid-phase extraction and high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;690(1-2):363-6.
1997: Jan-Olof Svensson; Christina Brattström; Juliette Säwe
Determination of rapamycin in whole blood by HPLC.
Therapeutic drug monitoring 1997;19(1):112-6.
1997: M Eriksson-Mjöberg; Jan-Olof Svensson; O Almkvist; A Olund; Lars ´Gustafsson
Extradural morphine gives better pain relief than patient-controlled i.v. morphine after hysterectomy.
British journal of anaesthesia 1997;78(1):10-6.
1996: Juan Antonio Carrillo; Marja-Liisa Dahl; Jan-Olof Svensson; C Alm; I Rodríguez; Leif Bertilsson
Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity.
Clinical pharmacology and therapeutics 1996;60(2):183-90.
1996: Jan Hasselström; Jan-Olof Svensson; Juliette Säwe; Z Wiesenfeld-Hallin; QY Yue; X J Xu
Disposition and analgesic effects of systemic morphine, morphine-6-glucuronide and normorphine in rat.
Pharmacology & toxicology 1996;79(1):40-6.
1995: Jan-Olof Svensson; QY Yue; Juliette Säwe
Determination of codeine and metabolites in plasma and urine using ion-pair high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1995;674(1):49-55.
1995: QY Yue; Jan-Olof Svensson; Juliette Säwe; Leif Bertilsson
Codeine metabolism in three Oriental populations: a pilot study in Chinese, Japanese and Koreans.
Pharmacogenetics 1995;5(3):173-7.
1993: Marja-Liisa Dahl; L Iselius; C Alm; Jan-Olof Svensson; D Lee; Inger Johansson; Magnus Ingelman-Sundberg; Folke Sjöqvist
Polymorphic 2-hydroxylation of desipramine. A population and family study.
European journal of clinical pharmacology 1993;44(5):445-50.
1992: Gilles Paintaud; Gunnar Alván; Marja-Liisa Dahl; A Grahnén; J Sjövall; Jan-Olof Svensson
Nonlinearity of amoxicillin absorption kinetics in human.
European journal of clinical pharmacology 1992;43(3):283-8.
1992: J Sjövall; Gunnar Alván; J E Akerlund; Jan-Olof Svensson; Gilles Paintaud; C E Nord; Bo Angelin
Dose-dependent absorption of amoxicillin in patients with an ileostomy.
European journal of clinical pharmacology 1992;43(3):277-81.
1991: QY Yue; Jan-Olof Svensson; Folke Sjöqvist; Juliette Säwe
A comparison of the pharmacokinetics of codeine and its metabolites in healthy Chinese and Caucasian extensive hydroxylators of debrisoquine.
British journal of clinical pharmacology 1991;31(6):643-7.
1991: QY Yue; Jan Hasselström; Jan-Olof Svensson; Juliette Säwe
Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons between extensive and poor hydroxylators of debrisoquine.
British journal of clinical pharmacology 1991;31(6):635-42.
1991: Jan Hasselström; N Alexander; C Bringel; Jan-Olof Svensson; Juliette Säwe
Single-dose and steady-state kinetics of morphine and its metabolites in cancer patients--a comparison of two oral formulations.
European journal of clinical pharmacology 1991;40(6):585-91.
1990: Jan Hasselström; S Eriksson; A Persson; A Rane; Jan-Olof Svensson; Juliette Säwe
The metabolism and bioavailability of morphine in patients with severe liver cirrhosis.
British journal of clinical pharmacology 1990;29(3):289-97.
1989: QY Yue; Jan-Olof Svensson; C Alm; Folke Sjöqvist; Juliette Säwe
Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation.
British journal of clinical pharmacology 1989;28(6):639-45.
1989: QY Yue; Jan-Olof Svensson; C Alm; Folke Sjöqvist; Juliette Säwe
Interindividual and interethnic differences in the demethylation and glucuronidation of codeine.
British journal of clinical pharmacology 1989;28(6):629-37.
1989: Torbjörn Tomson; Jan-Olof Svensson; P Hilton-Brown
Relationship of intraindividual dose to plasma concentration of carbamazepine: indication of dose-dependent induction of metabolism.
Therapeutic drug monitoring 1989;11(5):533-9.
1988: QY Yue; I Odar-Cederlöf; Jan-Olof Svensson; Juliette Säwe
Glucuronidation of morphine in human kidney microsomes.
Pharmacology & toxicology 1988;63(5):337-41.
1988: E Spina; Torbjörn Tomson; Jan-Olof Svensson; J W Faigle; Leif Bertilsson
Single-dose kinetics of an enteric-coated formulation of carbamazepine-10,11-epoxide, an active metabolite of carbamazepine.
Therapeutic drug monitoring 1988;10(4):382-5.
1985: Juliette Säwe; Jan-Olof Svensson; I Odar-Cederlöf
Kinetics of morphine in patients with renal failure.
Lancet 1985;2(8448):211.