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Francis Sweeney

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Molecular Structure

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Publications

TOP 3
Kim F McClure; Yuriy A Abramov; Ellen R Laird; John T Barberia; Weiling Cai; Thomas J Carty; Santo R Cortina; dennis danley; Alan J Dipesa; Kathleen M Donahue; Mark A Dombroski; Nancy C Elliott; Christopher A Gabel; Seungil Han; THOMAS HYNES; Peter K LeMotte; Mahmoud N Mansour; Eric S Marr; Michael A Letavic; Jayvardhan Pandit; David B Ripin; Francis J Sweeney; Douglas Tan; Yong Tao
Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.
Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Lilli A Wolf-Gouveia; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Ivan G Otterness; Marcia A Bliven; Thomas J Carty; John T Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn
Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Thomas J Carty; John A Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn; Joel R Hardink; Joel M Hawkins; Christopher Tokar
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13.

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All Publications

2005: Kim F McClure; Yuriy A Abramov; Ellen R Laird; John T Barberia; Weiling Cai; Thomas J Carty; Santo R Cortina; dennis danley; Alan J Dipesa; Kathleen M Donahue; Mark A Dombroski; Nancy C Elliott; Christopher A Gabel; Seungil Han; THOMAS HYNES; Peter K LeMotte; Mahmoud N Mansour; Eric S Marr; Michael A Letavic; Jayvardhan Pandit; David B Ripin; Francis J Sweeney; Douglas Tan; Yong Tao
Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.
Journal of medicinal chemistry 2005;48(18):5728-37.
2005: Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Lilli A Wolf-Gouveia; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Ivan G Otterness; Marcia A Bliven; Thomas J Carty; John T Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn
Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
Bioorganic & medicinal chemistry letters 2005;15(14):3385-8.
2005: Mark C Noe; Vijayalakshmi Natarajan; Sheri L Snow; Peter G Mitchell; Lori L Lopresti-Morrow; Lisa M Reeves; Sue A Yocum; Thomas J Carty; John A Barberia; Francis J Sweeney; Jennifer L Liras; Marcie Vaughn; Joel R Hardink; Joel M Hawkins; Christopher Tokar
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13.
Bioorganic & medicinal chemistry letters 2005;15(11):2808-11.
2004: Mark A Dombroski; Michael A Letavic; Kim F McClure; John T Barberia; Thomas J Carty; Santo R Cortina; Csilla Csiki; Alan J Dipesa; Nancy C Elliott; Christopher A Gabel; Crystal K Jordan; Jeffrey M Labasi; William Martin; Kevin M Peese; Ingrid A Stock; Linne Svensson; Francis J Sweeney; Chul H Yu
Benzimidazolone p38 inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(4):919-23.
2003: Michael A Letavic; John T Barberia; Thomas J Carty; Joel R Hardink; Jennifer L Liras; Lori L Lopresti-Morrow; Peter G Mitchell; Mark C Noe; Lisa M Reeves; Sheri L Snow; Ethan J Stam; Francis J Sweeney; Marcie Vaughn; Chul H Yu
Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitors.
Bioorganic & medicinal chemistry letters 2003;13(19):3243-6.
2003: Francis J Sweeney; Timothy S Wachtmann; James D Eskra; Kimberley A Verdries; Ralph H Lambalot; Thomas J Carty; Jose R Perez; Laurent P Audoly
Inhibition of IL-1beta-dependent prostaglandin E2 release by antisense microsomal prostaglandin E synthase 1 oligonucleotides in A549 cells.
Molecular and cellular endocrinology 2003;205(1-2):151-7.
2002: Michael A Letavic; Matt Z Axt; John T Barberia; Thomas J Carty; dennis danley; Kieran F Geoghegan; Nadia S Halim; Lise R Hoth; Ajith V Kamath; Ellen R Laird; Lori L Lopresti-Morrow; Kim F McClure; Peter G Mitchell; Vijayalakshmi Natarajan; Mark C Noe; Jayvardhan Pandit; Lisa M Reeves; Gayle K Schulte; Sheri L Snow; Francis J Sweeney; Douglas H Tan; Chul H Yu
Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.
Bioorganic & medicinal chemistry letters 2002;12(10):1387-90.
1997: Thomas J Carty; Francis J Sweeney; Richard J Griffiths; James D Eskra; M J Ernest; JS Pillar; J D Cheng; L D Loose; P A Joseph; P P Pazoles; Peter F Moore; Atsushi Nagahisa; S Murase; S B Kadin
Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46(5):168-79.