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Constanze Bonifer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Barton Jenny L; Bunka David H J; Knowling Stuart E; Lefevre Pascal; Warren Alan J; Bonifer Constanze; Stockley Peter G
Characterization of RNA aptamers that disrupt the RUNX1-CBFbeta/DNA complex.
Bruno Ludovica; Mazzarella Luca; Hoogenkamp Maarten; Hertweck Arnulf; Cobb Bradley S; Sauer Stephan; Hadjur Suzana; Leleu Marion; Naoe Yoshinori; Telfer Janice C; Bonifer Constanze; Taniuchi Ichiro; Fisher Amanda G; Merkenschlager Matthias
Runx proteins regulate Foxp3 expression.
Hoogenkamp Maarten; Lichtinger Monika; Krysinska Hanna; Lancrin Christophe; Clarke Deborah; Williamson Andrew; Mazzarella Luca; Ingram Richard; Jorgensen Helle; Fisher Amanda; Tenen Daniel G; Kouskoff Valerie; Lacaud Georges; Bonifer Constanze
Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program.

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2009: Barton Jenny L; Bunka David H J; Knowling Stuart E; Lefevre Pascal; Warren Alan J; Bonifer Constanze; Stockley Peter G
Characterization of RNA aptamers that disrupt the RUNX1-CBFbeta/DNA complex.
Nucleic acids research 2009;37(20):6818-30.
2009: Bruno Ludovica; Mazzarella Luca; Hoogenkamp Maarten; Hertweck Arnulf; Cobb Bradley S; Sauer Stephan; Hadjur Suzana; Leleu Marion; Naoe Yoshinori; Telfer Janice C; Bonifer Constanze; Taniuchi Ichiro; Fisher Amanda G; Merkenschlager Matthias
Runx proteins regulate Foxp3 expression.
The Journal of experimental medicine 2009;206(11):2329-37.
2009: Hoogenkamp Maarten; Lichtinger Monika; Krysinska Hanna; Lancrin Christophe; Clarke Deborah; Williamson Andrew; Mazzarella Luca; Ingram Richard; Jorgensen Helle; Fisher Amanda; Tenen Daniel G; Kouskoff Valerie; Lacaud Georges; Bonifer Constanze
Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program.
Blood 2009;114(2):299-309.
2009: Decker Thorsten; Pasca di Magliano Marina; McManus Shane; Sun Qiong; Bonifer Constanze; Tagoh Hiromi; Busslinger Meinrad
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Immunity 2009;30(4):508-20.
2008: Lefevre Pascal; Witham James; Lacroix Claire E; Cockerill Peter N; Bonifer Constanze
The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.
Molecular cell 2008;32(1):129-39.
2008: Walter Korden; Bonifer Constanze; Tagoh Hiromi
Stem cell-specific epigenetic priming and B cell-specific transcriptional activation at the mouse Cd19 locus.
Blood 2008;112(5):1673-82.
2008: Ebralidze Alexander K; Guibal Florence C; Steidl Ulrich; Zhang Pu; Lee Sanghoon; Bartholdy Boris; Jorda Meritxell Alberich; Petkova Victoria; Rosenbauer Frank; Huang Gang; Dayaram Tajhal; Klupp Johanna; O'Brien Karen B; Will Britta; Hoogenkamp Maarten; Borden Katherine L B; Bonifer Constanze; Tenen Daniel G
PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.
Genes & development 2008;22(15):2085-92.
2008: Bonifer Constanze; Hoogenkamp Maarten; Krysinska Hanna; Tagoh Hiromi
How transcription factors program chromatin--lessons from studies of the regulation of myeloid-specific genes.
Seminars in immunology 2008;20(4):257-63.
2008: Plachetka Annette; Chayka Olesya; Wilczek Carola; Melnik Svitlana; Bonifer Constanze; Klempnauer Karl-Heinz
C/EBPbeta induces chromatin opening at a cell-type-specific enhancer.
Molecular and cellular biology 2008;28(6):2102-12.
2008: Ingram R; Gao C; Lebon J; Liu Q; Mayoral R J; Sommer S S; Hoogenkamp M; Riggs A D; Bonifer C
PAP-LMPCR for improved, allele-specific footprinting and automated chromatin fine structure analysis.
Nucleic acids research 2008;36(3):e19.
2008: Bonifer Constanze; Hume David A
The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis.
Frontiers in bioscience : a journal and virtual library 2008;13():549-60.
2007: Hoogenkamp Maarten; Krysinska Hanna; Ingram Richard; Huang Gang; Barlow Rachael; Clarke Deborah; Ebralidze Alexander; Zhang Pu; Tagoh Hiromi; Cockerill Peter N; Tenen Daniel G; Bonifer Constanze
The Pu.1 locus is differentially regulated at the level of chromatin structure and noncoding transcription by alternate mechanisms at distinct developmental stages of hematopoiesis.
Molecular and cellular biology 2007;27(21):7425-38.
2007: Lichtinger Monika; Ingram Richard; Hornef Mathias; Bonifer Constanze; Rehli Michael
Transcription factor PU.1 controls transcription start site positioning and alternative TLR4 promoter usage.
The Journal of biological chemistry 2007;282(37):26874-83.
2007: Jieping Chen; Clarke Deborah; Bonifer Constanze
Reduced c-myb expression levels affect hematopoietic development in vitro.
International journal of hematology 2007;85(4):312-6.
2007: DeKoter Rodney P; Schweitzer Brock L; Kamath Meghana B; Jones Darrel; Tagoh Hiromi; Bonifer Constanze; Hildeman David A; Huang Kelly J
Regulation of the interleukin-7 receptor alpha promoter by the Ets transcription factors PU.1 and GA-binding protein in developing B cells.
The Journal of biological chemistry 2007;282(19):14194-204.
2007: Krysinska Hanna; Hoogenkamp Maarten; Ingram Richard; Wilson Nicola; Tagoh Hiromi; Laslo Peter; Singh Harinder; Bonifer Constanze
A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene.
Molecular and cellular biology 2007;27(3):878-87.
2006: Tagoh Hiromi; Ingram Richard; Wilson Nicola; Salvagiotto Giorgia; Warren Alan J; Clarke Deborah; Busslinger Meinrad; Bonifer Constanze
The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.
The EMBO journal 2006;25(5):1070-80.
2006: Hull M A; Faluyi O O; Ko C W S; Holwell S; Scott D J; Cuthbert R J; Poulsom R; Goodlad R; Bonifer C; Markham A F; Coletta P L
Regulation of stromal cell cyclooxygenase-2 in the ApcMin/+ mouse model of intestinal tumorigenesis.
Carcinogenesis 2006;27(3):382-91.
2006: Myers Fiona A; Lefevre Pascal; Mantouvalou Evangelia; Bruce Kimberley; Lacroix Claire; Bonifer Constanze; Thorne Alan W; Crane-Robinson Colyn
Developmental activation of the lysozyme gene in chicken macrophage cells is linked to core histone acetylation at its enhancer elements.
Nucleic acids research 2006;34(14):4025-35.
2006: Bonifer C; Lefevre P; Tagoh H
The regulation of chromatin and DNA-methylation patterns in blood cell development.
Current topics in microbiology and immunology 2006;310():1-12.
2006: Lefevre Pascal; Bonifer Constanze
Analyzing histone modification using crosslinked chromatin treated with micrococcal nuclease.
Methods in molecular biology (Clifton, N.J.) 2006;325():315-25.
2006: Tagoh Hiromi; Cockerill Peter N; Bonifer Constanze
In vivo genomic footprinting using LM-PCR methods.
Methods in molecular biology (Clifton, N.J.) 2006;325():285-314.
2005: Lefevre Pascal; Lacroix Claire; Tagoh Hiromi; Hoogenkamp Maarten; Melnik Svitlana; Ingram Richard; Bonifer Constanze
Differentiation-dependent alterations in histone methylation and chromatin architecture at the inducible chicken lysozyme gene.
The Journal of biological chemistry 2005;280(30):27552-60.
2005: Follows George Alexander; Tagoh Hiromi; Richards Stephen John; Melnik Svitlana; Dickinson Helen; de Wynter Erica; Lefevre Pascal; Morgan Gareth John; Bonifer Constanze
c-FMS chromatin structure and expression in normal and leukaemic myelopoiesis.
Oncogene 2005;24(22):3643-51.
2005: Bonifer Constanze
Epigenetic plasticity of hematopoietic cells.
Cell cycle (Georgetown, Tex.) 2005;4(2):211-4.
2005: Bruce Kimberley; Myers Fiona A; Mantouvalou Evangelia; Lefevre Pascal; Greaves Ian; Bonifer Constanze; Tremethick David J; Thorne Alan W; Crane-Robinson Colyn
The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken.
Nucleic acids research 2005;33(17):5633-9.
2005: Ingram Richard; Tagoh Hiromi; Riggs Arthur D; Bonifer Constanze
Rapid, solid-phase based automated analysis of chromatin structure and transcription factor occupancy in living eukaryotic cells.
Nucleic acids research 2005;33(1):e1.
2004: Stadler Sonja; Schnapp Verena; Mayer Robert; Stein Stefan; Cremer Christoph; Bonifer Constanze; Cremer Thomas; Dietzel Steffen
The architecture of chicken chromosome territories changes during differentiation.
BMC cell biology 2004;5(1):44.
2004: Tagoh Hiromi; Schebesta Alexandra; Lefevre Pascal; Wilson Nicola; Hume David; Busslinger Meinrad; Bonifer Constanze
Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.
The EMBO journal 2004;23(21):4275-85.
2004: Tagoh Hiromi; Melnik Svitlana; Lefevre Pascal; Chong Suyinn; Riggs Arthur D; Bonifer Constanze
Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro.
Blood 2004;103(8):2950-5.
2004: Coletta P Louise; Müller Albrecht M; Jones Elena A; Mühl Bettina; Holwell Sarah; Clarke Deborah; Meade Josephine L; Cook Graham P; Hawcroft Gillian; Ponchel Frederique; Lam Wai K; MacLennan Ken A; Hull Mark A; Bonifer Constanze; Markham Alexander F
Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis.
Blood 2004;103(3):1050-8.
2003: Follows George A; Tagoh Hiromi; Lefevre Pascal; Morgan Gareth J; Bonifer Constanze
Differential transcription factor occupancy but evolutionarily conserved chromatin features at the human and mouse M-CSF (CSF-1) receptor loci.
Nucleic acids research 2003;31(20):5805-16.
2003: Lefevre Pascal; Melnik Svitlana; Wilson Nicola; Riggs Arthur D; Bonifer Constanze
Developmentally regulated recruitment of transcription factors and chromatin modification activities to chicken lysozyme cis-regulatory elements in vivo.
Molecular and cellular biology 2003;23(12):4386-400.
2003: Follows George A; Tagoh Hiromi; Lefevre Pascal; Hodge Donald; Morgan Gareth J; Bonifer Constanze
Epigenetic consequences of AML1-ETO action at the human c-FMS locus.
The EMBO journal 2003;22(11):2798-809.
2003: Rance James B; Follows George A; Cockerill Peter N; Bonifer Constanze; Lane David A; Simmonds Rachel E
Regulation of the human endothelial cell protein C receptor gene promoter by multiple Sp1 binding sites.
Blood 2003;101(11):4393-401.
2003: Lutz Marcus; Burke Les J; LeFevre Pascal; Myers Fiona A; Thorne Alan W; Crane-Robinson Colyn; Bonifer Constanze; Filippova Galina N; Lobanenkov Victor; Renkawitz Rainer
Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor.
The EMBO journal 2003;22(7):1579-87.
2002: Tagoh Hiromi; Himes Roy; Clarke Deborah; Leenen Pieter J M; Riggs Arthur D; Hume David; Bonifer Constanze
Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells.
Genes & development 2002;16(13):1721-37.
2002: Chong Suyinn; Kontaraki Joanna; Bonifer Constanze; Riggs Arthur D
A Functional chromatin domain does not resist X chromosome inactivation: silencing of cLys correlates with methylation of a dual promoter-replication origin.
Molecular and cellular biology 2002;22(13):4667-76.
2002: Chong Suyinn; Riggs Arthur D; Bonifer Constanze
The chicken lysozyme chromatin domain contains a second, widely expressed gene.
Nucleic acids research 2002;30(2):463-7.
2001: Lefevre P; Kontaraki J; Bonifer C
Identification of factors mediating the developmental regulation of the early acting -3.9 kb chicken lysozyme enhancer element.
Nucleic acids research 2001;29(22):4551-60.
2001: Himes S R; Tagoh H; Goonetilleke N; Sasmono T; Oceandy D; Clark R; Bonifer C; Hume D A
A highly conserved c-fms gene intronic element controls macrophage-specific and regulated expression.
Journal of leukocyte biology 2001;70(5):812-20.
2001: Scott D J; Hull M A; Cartwright E J; Lam W K; Tisbury A; Poulsom R; Markham A F; Bonifer C; Coletta P L
Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse.
Gastroenterology 2001;121(4):889-99.
2001: Chen H H; Kontaraki J; Bonifer C; Riggs A D
Terminal transferase-dependent PCR (TDPCR) for in vivo UV photofootprinting of vertebrate cells.
Science's STKE : signal transduction knowledge environment 2001;2001(77):pl1.
2000: Kontaraki J; Chen H H; Riggs A; Bonifer C
Chromatin fine structure profiles for a developmentally regulated gene: reorganization of the lysozyme locus before trans-activator binding and gene expression.
Genes & development 2000;14(16):2106-22.
2000: Clarke D; Vegiopoulos A; Crawford A; Mucenski M; Bonifer C; Frampton J
In vitro differentiation of c-myb(-/-) ES cells reveals that the colony forming capacity of unilineage macrophage precursors and myeloid progenitor commitment are c-Myb independent.
Oncogene 2000;19(30):3343-51.
2000: Bonifer C
Developmental regulation of eukaryotic gene loci: which cis-regulatory information is required?
Trends in genetics : TIG 2000;16(7):310-5.
2000: Stevenson A J; Clarke D; Meredith D M; Kinsey S E; Whitehouse A; Bonifer C
Herpesvirus saimiri-based gene delivery vectors maintain heterologous expression throughout mouse embryonic stem cell differentiation in vitro.
Gene therapy 2000;7(6):464-71.
2000: Chapple K S; Cartwright E J; Hawcroft G; Tisbury A; Bonifer C; Scott N; Windsor A C; Guillou P J; Markham A F; Coletta P L; Hull M A
Localization of cyclooxygenase-2 in human sporadic colorectal adenomas.
The American journal of pathology 2000;156(2):545-53.
1999: Bonifer C
Long-distance chromatin mechanisms controlling tissue-specific gene locus activation.
Gene 1999;238(2):277-89.
1999: Faust N; Bonifer C; Sippel A E
Differential activity of the -2.7 kb chicken lysozyme enhancer in macrophages of different ontogenic origins is regulated by C/EBP and PU.1 transcription factors.
DNA and cell biology 1999;18(8):631-42.
1999: Krüger G; Huber M C; Bonifer C
The -3.9 kb DNaseI hypersensitive site of the chicken lysozyme locus harbours an enhancer with unusual chromatin reorganizing activity.
Gene 1999;236(1):63-77.
1999: Hull M A; Booth J K; Tisbury A; Scott N; Bonifer C; Markham A F; Coletta P L
Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.
British journal of cancer 1999;79(9-10):1399-405.
1998: Geiger H; Sick S; Bonifer C; Müller A M
Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts.
Cell 1998;93(6):1055-65.
1998: Bonifer C; Faust N; Geiger H; Müller A M
Developmental changes in the differentiation capacity of haematopoietic stem cells.
Immunology today 1998;19(5):236-41.
1997: Bonifer C; Jägle U; Huber M C
The chicken lysozyme locus as a paradigm for the complex developmental regulation of eukaryotic gene loci.
The Journal of biological chemistry 1997;272(42):26075-8.
1997: Huber M C; Jägle U; Krüger G; Bonifer C
The developmental activation of the chicken lysozyme locus in transgenic mice requires the interaction of a subset of enhancer elements with the promoter.
Nucleic acids research 1997;25(15):2992-3000.
1997: Faust N; Huber M C; Sippel A E; Bonifer C
Different macrophage populations develop from embryonic/fetal and adult hematopoietic tissues.
Experimental hematology 1997;25(5):432-44.
1997: Jägle U; Müller A M; Kohler H; Bonifer C
Role of positive and negative cis-regulatory elements in the transcriptional activation of the lysozyme locus in developing macrophages of transgenic mice.
The Journal of biological chemistry 1997;272(9):5871-9.
1996: Bonifer C; Huber M C; Jägle U; Faust N; Sippel A E
Prerequisites for tissue specific and position independent expression of a gene locus in transgenic mice.
Journal of molecular medicine (Berlin, Germany) 1996;74(11):663-71.
1996: Huber M C; Krüger G; Bonifer C
Genomic position effects lead to an inefficient reorganization of nucleosomes in the 5'-regulatory region of the chicken lysozyme locus in transgenic mice.
Nucleic acids research 1996;24(8):1443-52.
1996: Sippel A E; Saueressig H; Huber M C; Hoefer H C; Stief A; Borgmeyer U; Bonifer C
Identification of cis-acting elements as DNase I hypersensitive sites in lysozyme gene chromatin.
Methods in enzymology 1996;274():233-46.
1996: Bonifer C; Huber M C; Faust N; Sippel A E
Regulation of the chicken lysozyme locus in transgenic mice.
Critical reviews in eukaryotic gene expression 1996;6(2-3):285-97.
1995: Huber M C; Graf T; Sippel A E; Bonifer C
Dynamic changes in the chromatin of the chicken lysozyme gene domain during differentiation of multipotent progenitors to macrophages.
DNA and cell biology 1995;14(5):397-402.
1994: Bonifer C; Bosch F X; Faust N; Schuhmann A; Sippel A E
Evolution of gene regulation as revealed by differential regulation of the chicken lysozyme transgene and the endogenous mouse lysozyme gene in mouse macrophages.
European journal of biochemistry / FEBS 1994;226(1):227-35.
1994: Bonifer C; Yannoutsos N; Krüger G; Grosveld F; Sippel A E
Dissection of the locus control function located on the chicken lysozyme gene domain in transgenic mice.
Nucleic acids research 1994;22(20):4202-10.
1994: Huber M C; Bosch F X; Sippel A E; Bonifer C
Chromosomal position effects in chicken lysozyme gene transgenic mice are correlated with suppression of DNase I hypersensitive site formation.
Nucleic acids research 1994;22(20):4195-201.
1994: Faust N; Bonifer C; Wiles M V; Sippel A E
An in vitro differentiation system for the examination of transgene activation in mouse macrophages.
DNA and cell biology 1994;13(9):901-7.
1993: Sippel A E; Schäfer G; Faust N; Saueressig H; Hecht A; Bonifer C
Chromatin domains constitute regulatory units for the control of eukaryotic genes.
Cold Spring Harbor symposia on quantitative biology 1993;58():37-44.
1991: Bonifer C; Hecht A; Saueressig H; Winter D M; Sippel A E
Dynamic chromatin: the regulatory domain organization of eukaryotic gene loci.
Journal of cellular biochemistry 1991;47(2):99-108.
1990: Bonifer C; Vidal M; Grosveld F; Sippel A E
Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice.
The EMBO journal 1990;9(9):2843-8.
1988: Bonifer C; Hecht A; Peters C W; Sippel A E
Rat antibodies as probes for the characterization of progesterone receptor A and B proteins from laying hen oviduct cytosol.
Biochimica et biophysica acta 1988;968(1):96-108.
1986: Klempnauer K H; Bonifer C; Sippel A E
Identification and characterization of the protein encoded by the human c-myb proto-oncogene.
The EMBO journal 1986;5(8):1903-11.

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Constanze Bonifer

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Anatomy

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