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Rosemarie Syhre

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Célia Fernandes; João D G Correia; Lurdes Gano; Isabel Santos; Sepp Seifert; Rosemarie Syhre; Ralf Bergmann; Hartmut Spies
Dramatic effect of the tridentate ligand on the stability of 99mTC "3 + 1" oxo complexes bearing arylpiperazine derivatives.
Sepp Seifert; Rosemarie Syhre; Hartmut Spies; Bernd Johannsen
Novel tumortropic ester derivatives of 99mTc(V) mesodimercapto succinic acid with low affinity for bone tissue.
Hans-Jürgen Pietzsch; Sepp Seifert; Rosemarie Syhre; Francesco Tisato; Fiorenzo Refosco; Peter Leibnitz; Hartmut Spies
Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH(3)), S): a novel approach to robust technetium chelates suitable for linking the metal to biomolecules.

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All Publications

2005: Célia Fernandes; João D G Correia; Lurdes Gano; Isabel Santos; Sepp Seifert; Rosemarie Syhre; Ralf Bergmann; Hartmut Spies
Dramatic effect of the tridentate ligand on the stability of 99mTC "3 + 1" oxo complexes bearing arylpiperazine derivatives.
Bioconjugate chemistry 2005;16(3):660-8.
2003: Sepp Seifert; Rosemarie Syhre; Hartmut Spies; Bernd Johannsen
Novel tumortropic ester derivatives of 99mTc(V) mesodimercapto succinic acid with low affinity for bone tissue.
Nuclear medicine communications 2003;24(11):1175-83.
2003: Hans-Jürgen Pietzsch; Sepp Seifert; Rosemarie Syhre; Francesco Tisato; Fiorenzo Refosco; Peter Leibnitz; Hartmut Spies
Synthesis, characterization, and biological evaluation of technetium(III) complexes with tridentate/bidentate S,E,S/P,S coordination (E = O, N(CH(3)), S): a novel approach to robust technetium chelates suitable for linking the metal to biomolecules.
Bioconjugate chemistry 2003;14(1):136-43.
2002: Hartmut Spies; Bernhard Noll; Steffi Noll; M Findeisen; Peter Brust; Rosemarie Syhre; R Berger
Tc and Re chelates of 8alpha-amino-6-methyl-ergoline: synthesis and affinity to the dopamine D2 receptor.
Bioorganic & medicinal chemistry 2002;10(11):3523-8.
2002: Antje Drews; Hans-Jürgen Pietzsch; Rosemarie Syhre; Sepp Seifert; K Varnäs; Håkan Hall; Christer Halldin; Werner Kraus; P Karlsson; C Johnsson; Hartmut Spies; Bernd Johannsen
Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT(1A) receptor and the alpha1-adrenergic receptor.
Nuclear medicine and biology 2002;29(4):389-98.
2002: I Heimbold; Antje Drews; Marion Kretzschmar; K Varnäs; Håkan Hall; Christer Halldin; Rosemarie Syhre; Werner Kraus; Hans-Jürgen Pietzsch; Sepp Seifert; Peter Brust; Bernd Johannsen
Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor.
Nuclear medicine and biology 2002;29(4):375-87.
2002: Ilka Heimbold; Antje Drews; Rosemarie Syhre; Marion Kretzschmar; Hans-Jürgen Pietzsch; Bernd Johannsen
A novel technetium-99m radioligand for the 5-HT(1A) receptor derived from desmethyl-WAY-100635 (DWAY).
European journal of nuclear medicine and molecular imaging 2002;29(1):82-7.
2001: Hans-Jürgen Pietzsch; A Gupta; Rosemarie Syhre; Peter Leibnitz; Hartmut Spies
Mixed-ligand technetium(III) complexes with tetradendate/monodendate NS(3)/isocyanide coordination: a new nonpolar technetium chelate system for the design of neutral and lipophilic complexes stable in vivo.
Bioconjugate chemistry 2001;12(4):538-44.
2001: Sepp Seifert; A Gupta; Rosemarie Syhre; Hartmut Spies; Bernd Johannsen
Ligand-exchange reaction of labile "3 + 1"99mTc(V) complexes with SH group-containing proteins.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2001;54(4):637-44.
2000: Matthias Friebe; K Suda; H Spies; Rosemarie Syhre; R Berger; Bernd Johannsen; E Chiotellis; Stefanie D Krämer; Heidi Wunderli-Allenspach
Permeation studies in vitro and in vivo of potential radiopharmaceuticals with affinity to neuro receptors.
Pharmaceutical research 2000;17(6):754-60.
2000: Hans-Jürgen Pietzsch; A Gupta; M Reisgys; Antje Drews; Sepp Seifert; Rosemarie Syhre; Hartmut Spies; Roger Alberto; Ulrich Abram; P August Schubiger; Bernd Johannsen
Chemical and biological characterization of technetium(I) and Rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers for coupling the Tc(CO)(3) and Re(CO)(3) moieties to biologically active molecules.
Bioconjugate chemistry 2000;11(3):414-24.
2000: MB Skaddan; Frank Wüst; SD Jonson; Rosemarie Syhre; Michael J Welch; Hartmut Spies; John A Katzenellenbogen
Radiochemical synthesis and tissue distribution of Tc-99m-labeled 7alpha-substituted estradiol complexes.
Nuclear medicine and biology 2000;27(3):269-78.
1999: Hans-Jürgen Pietzsch; Matthias Scheunemann; Marion Kretzschmar; Sigurd Elz; Heinz H Pertz; Sepp Seifert; Peter Brust; Hartmut Spies; Rosemarie Syhre; Bernd Johannsen
Synthesis and autoradiographic evaluation of a novel high-affinity Tc-99m ligand for the 5-HT2A receptor.
Nuclear medicine and biology 1999;26(8):865-75.
1998: Rosemarie Syhre; Sepp Seifert; Hartmut Spies; A Gupta; Bernd Johannsen
Stability versus reactivity of "3+1" mixed-ligand technetium-99m complexes in vitro and in vivo.
European journal of nuclear medicine 1998;25(7):793-6.
1997: Bernd Johannsen; R Berger; Peter Brust; Hans-Jürgen Pietzsch; Matthias Scheunemann; Sepp Seifert; Hartmut Spies; Rosemarie Syhre
Structural modification of receptor-binding technetium-99m complexes in order to improve brain uptake.
European journal of nuclear medicine 1997;24(3):316-9.
1996: Bernd Johannsen; Matthias Scheunemann; Hartmut Spies; Peter Brust; Jannette Wober; Rosemarie Syhre; Hans-Jürgen Pietzsch
Technetium(V) and rhenium(V) complexes for 5-HT2A serotonin receptor binding: structure-affinity considerations.
Nuclear medicine and biology 1996;23(4):429-38.
1986: J Schmidt; W Mohnike; P Muschik; D Nickles; Sepp Seifert; Rosemarie Syhre; H Bach; W Hartrodt; E Rohde; R Münze
[Results of animal experiment tests of technetium-99m-DMPE in minipigs].
Radiobiologia, radiotherapia 1986;27(1):97-100.
1986: Rosemarie Syhre; Sepp Seifert; R Münze; W Mohnike; J Schmidt; K H Brosowski; P Muschick
[Comparison of the biokinetic parameters of [99mTc(DMPE)]-complexes with myocardial affinity].
Radiobiologia, radiotherapia 1986;27(1):94-6.
1986: R Berger; Rosemarie Syhre; Sepp Seifert; D Klötzer; P Mäding; R Münze
Preparation of [99mTc(DMPE)2Cl2]+ for myocardial imaging by using Fe-(DMPE) complexes.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1986;37(3):197-200.
1980: Rosemarie Syhre; Bernd Johannsen
[A closed tract of boxes for animal experiments with radioactive compounds].
Zeitschrift für Versuchstierkunde 1980;22(1):8-12.