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Brian Sykes

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Biomolecular Nuclear Magnetic Resonance

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Co-Publications
Name
32
Hodges, Robert
27
Li, Monica
23
Kay, Cyril
21
Davies, Peter
20
Clark-Lewis, Ian
20
Spyracopoulos, Leo
19
Slupsky, Carolyn
17
Campbell, Patricia
17
Gagné, Stéphane
13
Rajarathnam, Krishna
12
Crump, Matthew
12
Smillie, Lawrence
11
Wishart, David
11
Graether, Steffen
10
Irvin, Randall

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Publications

TOP 3
Julien Olivier; Chatterjee Subhrangsu; Thiessen Angela; Graether Steffen P; Sykes Brian D
Differential stability of the bovine prion protein upon urea unfolding.
Robertson Ian M; Li Monica X; Sykes Brian D
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate.
Friis R Magnus N; Wu Bob P; Reinke Stacey N; Hockman Darren J; Sykes Brian D; Schultz Michael C
A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA.

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All Publications

2009: Julien Olivier; Chatterjee Subhrangsu; Thiessen Angela; Graether Steffen P; Sykes Brian D
Differential stability of the bovine prion protein upon urea unfolding.
Protein science : a publication of the Protein Society 2009;18(10):2172-82.
2009: Robertson Ian M; Li Monica X; Sykes Brian D
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate.
The Journal of biological chemistry 2009;284(34):23012-23.
2009: Friis R Magnus N; Wu Bob P; Reinke Stacey N; Hockman Darren J; Sykes Brian D; Schultz Michael C
A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA.
Nucleic acids research 2009;37(12):3969-80.
2009: Julien Olivier; Mercier Pascal; Crane Melissa L; Sykes Brian D
The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C.
Protein science : a publication of the Protein Society 2009;18(6):1165-74.
2009: Hoffman Ryan M B; Sykes Brian D
Structure of the inhibitor W7 bound to the regulatory domain of cardiac troponin C.
Biochemistry 2009;48(24):5541-52.
2009: Lee Brian L; Li Xiuju; Liu Yongsheng; Sykes Brian D; Fliegel Larry
Structural and functional analysis of transmembrane XI of the NHE1 isoform of the Na+/H+ exchanger.
The Journal of biological chemistry 2009;284(17):11546-56.
2009: Julien Olivier; Graether Steffen P; Sykes Brian D
Monitoring prion protein stability by NMR.
Journal of toxicology and environmental health. Part A 2009;72(17):1069-74.
2008: Hoffman Ryan M B; Sykes Brian D
Isoform-specific variation in the intrinsic disorder of troponin I.
Proteins 2008;73(2):338-50.
2008: Baryshnikova Olga K; Robertson Ian M; Mercier Pascal; Sykes Brian D
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
Biochemistry 2008;47(41):10950-60.
2008: Robertson Ian M; Baryshnikova Olga K; Li Monica X; Sykes Brian D
Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex.
Biochemistry 2008;47(28):7485-95.
2008: Baryshnikova Olga K; Williams Thomas C; Sykes Brian D
Internal pH indicators for biomolecular NMR.
Journal of biomolecular NMR 2008;41(1):5-7.
2008: Li Monica X; Robertson Ian M; Sykes Brian D
Interaction of cardiac troponin with cardiotonic drugs: a structural perspective.
Biochemical and biophysical research communications 2008;369(1):88-99.
2008: Julien Olivier; Mercier Pascal; Spyracopoulos Leo; Corrie John E T; Sykes Brian D
NMR studies of the dynamics of a bifunctional rhodamine probe attached to troponin C.
Journal of the American Chemical Society 2008;130(8):2602-9.
2008: Julien Olivier; Sun Yin-Biao; Wang Xu; Lindhout Darrin A; Thiessen Angela; Irving Malcolm; Sykes Brian D
Tryptophan mutants of cardiac troponin C: 3D structure, troponin I affinity, and in situ activity.
Biochemistry 2008;47(2):597-606.
2008: Baryshnikova Olga K; Li Monica X; Sykes Brian D
Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies.
Journal of molecular biology 2008;375(3):735-51.
2007: Slupsky Carolyn M; Rankin Kathryn N; Wagner James; Fu Hao; Chang David; Weljie Aalim M; Saude Erik J; Lix Bruce; Adamko Darryl J; Shah Sirish; Greiner Russ; Sykes Brian D; Marrie Thomas J
Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles.
Analytical chemistry 2007;79(18):6995-7004.
2007: Szeto Samuel S W; Reinke Stacey N; Sykes Brian D; Lemire Bernard D
Ubiquinone-binding site mutations in the Saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate.
The Journal of biological chemistry 2007;282(37):27518-26.
2007: Julien Olivier; Sun Yin-Biao; Knowles Andrea C; Brandmeier Birgit D; Dale Robert E; Trentham David R; Corrie John E T; Sykes Brian D; Irving Malcolm
Toward protein structure in situ: comparison of two bifunctional rhodamine adducts of troponin C.
Biophysical journal 2007;93(3):1008-20.
2007: Zhao Xingang; DeVries Jeffrey S; McDonald Robert; Sykes Brian D
Determination of the 19F NMR chemical shielding tensor and crystal structure of 5-fluoro-dl-tryptophan.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2007;187(1):88-96.
2007: Rainey Jan K; DeVries Jeffrey S; Sykes Brian D
Estimation and measurement of flat or solenoidal coil inductance for radiofrequency NMR coil design.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2007;187(1):27-37.
2007: Slupsky Carolyn M; Spyracopoulos Leo; Booth Valerie K; Sykes Brian D; Crump Matthew P
Probing nascent structures in peptides using natural abundance 13C NMR relaxation and reduced spectral density mapping.
Proteins 2007;67(1):18-30.
2007: Slepkov Emily R; Rainey Jan K; Sykes Brian D; Fliegel Larry
Structural and functional analysis of the Na+/H+ exchanger.
The Biochemical journal 2007;401(3):623-33.
2007: Scotter Andrew J; Guo Meng; Tomczak Melanie M; Daley Margaret E; Campbell Robert L; Oko Richard J; Bateman David A; Chakrabartty Avijit; Sykes Brian D; Davies Peter L
Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.
BMC structural biology 2007;7():63.
2007: Hoffman Ryan M B; Sykes Brian D
Disposition and dynamics: interdomain orientations in troponin.
Advances in experimental medicine and biology 2007;592():59-70.
2006: Rainey Jan K; Fliegel Larry; Sykes Brian D
Strategies for dealing with conformational sampling in structural calculations of flexible or kinked transmembrane peptides.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2006;84(6):918-29.
2006: Baryshnikova Olga K; Sykes Brian D
Backbone dynamics of SDF-1alpha determined by NMR: interpretation in the presence of monomer-dimer equilibrium.
Protein science : a publication of the Protein Society 2006;15(11):2568-78.
2006: Ding Jie; Rainey Jan K; Xu Caroline; Sykes Brian D; Fliegel Larry
Structural and functional characterization of transmembrane segment VII of the Na+/H+ exchanger isoform 1.
The Journal of biological chemistry 2006;281(40):29817-29.
2006: Li Monica X; Hoffman Ryan M B; Sykes Brian D
Interaction of cardiac troponin C with calmodulin antagonist [corrected] W7 in the presence of three functional regions of cardiac troponin I.
Biochemistry 2006;45(32):9833-40.
2006: Hoffman Ryan M B; Blumenschein Tharin M A; Sykes Brian D
An interplay between protein disorder and structure confers the Ca2+ regulation of striated muscle.
Journal of molecular biology 2006;361(4):625-33.
2006: Graether Steffen P; Slupsky Carolyn M; Sykes Brian D
Effect of a mutation on the structure and dynamics of an alpha-helical antifreeze protein in water and ice.
Proteins 2006;63(3):603-10.
2006: Blumenschein Tharin M A; Stone Deborah B; Fletterick Robert J; Mendelson Robert A; Sykes Brian D
Dynamics of the C-terminal region of TnI in the troponin complex in solution.
Biophysical journal 2006;90(7):2436-44.
2006: Graether Steffen P; DeVries Jeffrey S; McDonald Robert; Rakovszky Melissa L; Sykes Brian D
A 1H/19F minicoil NMR probe for solid-state NMR: application to 5-fluoroindoles.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;178(1):65-71.
2005: Baryshnikova O K; Rainey J K; Sykes B D
Nuclear magnetic resonance studies of CXC chemokine receptor 4 allosteric peptide agonists in solution.
The journal of peptide research : official journal of the American Peptide Society 2005;66 Suppl 1():12-21.
2005: Hoffman Ryan M B; Li Monica X; Sykes Brian D
The binding of W7, an inhibitor of striated muscle contraction, to cardiac troponin C.
Biochemistry 2005;44(48):15750-9.
2005: Lindhout Darrin A; Boyko Robert F; Corson David C; Li Monica X; Sykes Brian D
The role of electrostatics in the interaction of the inhibitory region of troponin I with troponin C.
Biochemistry 2005;44(45):14750-9.
2005: Rainey Jan K; Sykes Brian D
Optimizing oriented planar-supported lipid samples for solid-state protein NMR.
Biophysical journal 2005;89(4):2792-805.
2005: Wang Xu; Mercier Pascal; Letourneau Paul-Jean; Sykes Brian D
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein science : a publication of the Protein Society 2005;14(9):2447-60.
2005: Blumenschein Tharin M A; Stone Deborah B; Fletterick Robert J; Mendelson Robert A; Sykes Brian D
Calcium-dependent changes in the flexibility of the regulatory domain of troponin C in the troponin complex.
The Journal of biological chemistry 2005;280(23):21924-32.
2005: Slepkov Emily R; Rainey Jan K; Li Xiuju; Liu Yongsheng; Cheng Florence J; Lindhout Darrin A; Sykes Brian D; Fliegel Larry
Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
The Journal of biological chemistry 2005;280(18):17863-72.
2005: van Schaik Erin J; Giltner Carmen L; Audette Gerald F; Keizer David W; Bautista Daisy L; Slupsky Carolyn M; Sykes Brian D; Irvin Randall T
DNA binding: a novel function of Pseudomonas aeruginosa type IV pili.
Journal of bacteriology 2005;187(4):1455-64.
2004: Lindhout Darrin A; Litowski Jennifer R; Mercier Pascal; Hodges Robert S; Sykes Brian D
NMR solution structure of a highly stable de novo heterodimeric coiled-coil.
Biopolymers 2004;75(5):367-75.
2004: Daley Margaret E; Graether Steffen P; Sykes Brian D
Hydrogen bonding on the ice-binding face of a beta-helical antifreeze protein indicated by amide proton NMR chemical shifts.
Biochemistry 2004;43(41):13012-7.
2004: Saude Erik J; Lacy Paige; Musat-Marcu Sorin; Mayes Damon C; Bagu John; Man S F Paul; Sykes Brian D; Moqbel Redwan
NMR analysis of neutrophil activation in sputum samples from patients with cystic fibrosis.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;52(4):807-14.
2004: Marshall Christopher B; Daley Margaret E; Sykes Brian D; Davies Peter L
Enhancing the activity of a beta-helical antifreeze protein by the engineered addition of coils.
Biochemistry 2004;43(37):11637-46.
2004: Graether Steffen P; Sykes Brian D
Cold survival in freeze-intolerant insects: the structure and function of beta-helical antifreeze proteins.
European journal of biochemistry / FEBS 2004;271(16):3285-96.
2004: Booth Valerie; Clark-Lewis Ian; Sykes Brian D
NMR structure of CXCR3 binding chemokine CXCL11 (ITAC).
Protein science : a publication of the Protein Society 2004;13(8):2022-8.
2004: Daley Margaret E; Sykes Brian D
Characterization of threonine side chain dynamics in an antifreeze protein using natural abundance 13C NMR spectroscopy.
Journal of biomolecular NMR 2004;29(2):139-50.
2004: Blumenschein Tharin M A; Gillis Todd E; Tibbits Glen F; Sykes Brian D
Effect of temperature on the structure of trout troponin C.
Biochemistry 2004;43(17):4955-63.
2004: Gay Grant L; Lindhout Darrin A; Sykes Brian D
Using lanthanide ions to align troponin complexes in solution: order of lanthanide occupancy in cardiac troponin C.
Protein science : a publication of the Protein Society 2004;13(3):640-51.
2004: Li Monica X; Wang Xu; Sykes Brian D
Structural based insights into the role of troponin in cardiac muscle pathophysiology.
Journal of muscle research and cell motility 2004;25(7):559-79.
2003: Li Monica X; Wang Xu; Lindhout Darrin A; Buscemi Nina; Van Eyk Jennifer E; Sykes Brian D
Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C.
Biochemistry 2003;42(49):14460-8.
2003: Slupsky Carolyn M; Boyko Robert F; Booth Valerie K; Sykes Brian D
Smartnotebook: a semi-automated approach to protein sequential NMR resonance assignments.
Journal of biomolecular NMR 2003;27(4):313-21.
2003: Campbell A Patricia; Spyracopoulos Leo; Wong Wah Y; Irvin Randall T; Sykes Brian D
Interaction of a peptide from the receptor-binding domain of Pseudomonas aeruginosa pili strain PAK with a cross-reactive antibody: changes in backbone dynamics induced by binding.
Biochemistry 2003;42(38):11334-46.
2003: Lindhout Darrin A; Thiessen Angela; Schieve Dean; Sykes Brian D
High-yield expression of isotopically labeled peptides for use in NMR studies.
Protein science : a publication of the Protein Society 2003;12(8):1786-91.
2003: Daley Margaret E; Sykes Brian D
The role of side chain conformational flexibility in surface recognition by Tenebrio molitor antifreeze protein.
Protein science : a publication of the Protein Society 2003;12(7):1323-31.
2003: Willard Leigh; Ranjan Anuj; Zhang Haiyan; Monzavi Hassan; Boyko Robert F; Sykes Brian D; Wishart David S
VADAR: a web server for quantitative evaluation of protein structure quality.
Nucleic acids research 2003;31(13):3316-9.
2003: Lindhout Darrin A; Sykes Brian D
Structure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin I.
The Journal of biological chemistry 2003;278(29):27024-34.
2003: Raussens Vincent; Slupsky Carolyn M; Sykes Brian D; Ryan Robert O
Lipid-bound structure of an apolipoprotein E-derived peptide.
The Journal of biological chemistry 2003;278(28):25998-6006.
2003: Gillis Todd E; Blumenschein Tharin M A; Sykes Brian D; Tibbits Glen F
Effect of temperature and the F27W mutation on the Ca2+ activated structural transition of trout cardiac troponin C.
Biochemistry 2003;42(21):6418-26.
2003: Ferguson Roisean E; Sun Yin-Biao; Mercier Pascal; Brack Andrew S; Sykes Brian D; Corrie John E T; Trentham David R; Irving Malcolm
In situ orientations of protein domains: troponin C in skeletal muscle fibers.
Molecular cell 2003;11(4):865-74.
2003: Letourneau Paul-Jean; Boyko Robert; Sykes Brian D
PJNMR: a platform-independent graphical simulation tool for NMR spectroscopy.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2003;161(2):154-67.
2003: Mercier Pascal; Ferguson Roisean E; Irving Malcolm; Corrie John E T; Trentham David R; Sykes Brian D
NMR structure of a bifunctional rhodamine labeled N-domain of troponin C complexed with the regulatory "switch" peptide from troponin I: implications for in situ fluorescence studies in muscle fibers.
Biochemistry 2003;42(15):4333-48.
2003: Graether Steffen P; Gagné Stéphane M; Spyracopoulos Leo; Jia Zongchao; Davies Peter L; Sykes Brian D
Spruce budworm antifreeze protein: changes in structure and dynamics at low temperature.
Journal of molecular biology 2003;327(5):1155-68.
2003: Booth Valerie; Slupsky Carolyn M; Clark-Lewis Ian; Sykes Brian D
Unmasking ligand binding motifs: identification of a chemokine receptor motif by NMR studies of antagonist peptides.
Journal of molecular biology 2003;327(2):329-34.
2003: Graether Steffen P; Slupsky Carolyn M; Sykes Brian D
Freezing of a fish antifreeze protein results in amyloid fibril formation.
Biophysical journal 2003;84(1):552-7.
2003: Lakey Jonathan R T; Helms Lisa M H; Moser Gabrielle; Lix Bruce; Slupsky Carolyn M; Rebeyka Ivan M; Sykes Brian D; McGann Locksley E
Dynamics of cryoprotectant permeation in porcine heart valve leaflets.
Cell transplantation 2003;12(2):123-8.
2002: Marshall Christopher B; Daley Margaret E; Graham Laurie A; Sykes Brian D; Davies Peter L
Identification of the ice-binding face of antifreeze protein from Tenebrio molitor.
FEBS letters 2002;529(2-3):261-7.
2002: Booth Valerie; Keizer David W; Kamphuis Monique B; Clark-Lewis Ian; Sykes Brian D
The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions.
Biochemistry 2002;41(33):10418-25.
2002: Wang Xu; Li Monica X; Sykes Brian D
Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil.
The Journal of biological chemistry 2002;277(34):31124-33.
2002: Raussens Vincent; Slupsky Carolyn M; Ryan Robert O; Sykes Brian D
NMR structure and dynamics of a receptor-active apolipoprotein E peptide.
The Journal of biological chemistry 2002;277(32):29172-80.
2002: Li Monica X; Saude Erik J; Wang Xu; Pearlstone Joyce R; Smillie Lawrence B; Sykes Brian D
Kinetic studies of calcium and cardiac troponin I peptide binding to human cardiac troponin C using NMR spectroscopy.
European biophysics journal : EBJ 2002;31(4):245-56.
2002: Lindhout Darrin A; Li Monica X; Schieve Dean; Sykes Brian D
Effects of T142 phosphorylation and mutation R145G on the interaction of the inhibitory region of human cardiac troponin I with the C-domain of human cardiac troponin C.
Biochemistry 2002;41(23):7267-74.
2002: Daley Margaret E; Spyracopoulos Leo; Jia Zongchao; Davies Peter L; Sykes Brian D
Structure and dynamics of a beta-helical antifreeze protein.
Biochemistry 2002;41(17):5515-25.
2002: Li Monica X; Corson David C; Sykes Brian D
Structure determination by NMR. Isotope labeling.
Methods in molecular biology (Clifton, N.J.) 2002;173():255-65.
2001: Spyracopoulos L; Sykes B D
Thermodynamic insights into proteins from NMR spin relaxation studies.
Current opinion in structural biology 2001;11(5):555-9.
2001: Spyracopoulos L; Lavigne P; Crump M P; Gagné S M; Kay C M; Sykes B D
Temperature dependence of dynamics and thermodynamics of the regulatory domain of human cardiac troponin C.
Biochemistry 2001;40(42):12541-51.
2001: Graether S P; Slupsky C M; Davies P L; Sykes B D
Structure of type I antifreeze protein and mutants in supercooled water.
Biophysical journal 2001;81(3):1677-83.
2001: Blumenschein T M; Tripet B P; Hodges R S; Sykes B D
Mapping the interacting regions between troponins T and C. Binding of TnT and TnI peptides to TnC and NMR mapping of the TnT-binding site on TnC.
The Journal of biological chemistry 2001;276(39):36606-12.
2001: Mercier P; Spyracopoulos L; Sykes B D
Structure, dynamics, and thermodynamics of the structural domain of troponin C in complex with the regulatory peptide 1-40 of troponin I.
Biochemistry 2001;40(34):10063-77.
2001: Wang X; Li M X; Spyracopoulos L; Beier N; Chandra M; Solaro R J; Sykes B D
Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033.
The Journal of biological chemistry 2001;276(27):25456-66.
2001: Slupsky C M; Sykes D B; Gay G L; Sykes B D
The HoxB1 hexapeptide is a prefolded domain: implications for the Pbx1/Hox interaction.
Protein science : a publication of the Protein Society 2001;10(6):1244-53.
2001: Keizer D W; Slupsky C M; Kalisiak M; Campbell A P; Crump M P; Sastry P A; Hazes B; Irvin R T; Sykes B D
Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of pili.
The Journal of biological chemistry 2001;276(26):24186-93.
2001: Keizer D W; Kalisiak M; Crump M P; Suh J Y; Irvin R T; Sykes B D
Assignments of 1H and 15N resonances of the Pseudomonas aeruginosa K122-4 pilin monomer.
Journal of biomolecular NMR 2001;19(4):385-6.
2001: Suh J Y; Spyracopoulos L; Keizer D W; Irvin R T; Sykes B D
Backbone dynamics of receptor binding and antigenic regions of a Pseudomonas aeruginosa pilin monomer.
Biochemistry 2001;40(13):3985-95.
2001: Crump M P; Elisseeva E; Gong J; Clark-Lewis I; Sykes B D
Structure/function of human herpesvirus-8 MIP-II (1-71) and the antagonist N-terminal segment (1-10).
FEBS letters 2001;489(2-3):171-5.
2000: Campbell A P; Wong W Y; Irvin R T; Sykes B D
Interaction of a bacterially expressed peptide from the receptor binding domain of Pseudomonas aeruginosa pili strain PAK with a cross-reactive antibody: conformation of the bound peptide.
Biochemistry 2000;39(48):14847-64.
2000: Raussens V; Mah M K; Kay C M; Sykes B D; Ryan R O
Structural characterization of a low density lipoprotein receptor-active apolipoprotein E peptide, ApoE3-(126-183).
The Journal of biological chemistry 2000;275(49):38329-36.
2000: McKay R T; Saltibus L F; Li M X; Sykes B D
Energetics of the induced structural change in a Ca2+ regulatory protein: Ca2+ and troponin I peptide binding to the E41A mutant of the N-domain of skeletal troponin C.
Biochemistry 2000;39(41):12731-8.
2000: Doucet D; Tyshenko M G; Kuiper M J; Graether S P; Sykes B D; Daugulis A J; Davies P L; Walker V K
Structure-function relationships in spruce budworm antifreeze protein revealed by isoform diversity.
European journal of biochemistry / FEBS 2000;267(19):6082-8.
2000: Elisseeva E L; Slupsky C M; Crump M P; Clark-Lewis I; Sykes B D
NMR studies of active N-terminal peptides of stromal cell-derived factor-1. Structural basis for receptor binding.
The Journal of biological chemistry 2000;275(35):26799-805.
2000: Li M X; Spyracopoulos L; Beier N; Putkey J A; Sykes B D
Interaction of cardiac troponin C with Ca(2+) sensitizer EMD 57033 and cardiac troponin I inhibitory peptide.
Biochemistry 2000;39(30):8782-90.
2000: Campbell A P; Spyracopoulos L; Irvin R T; Sykes B D
Backbone dynamics of a bacterially expressed peptide from the receptor binding domain of Pseudomonas aeruginosa pilin strain PAK from heteronuclear 1H-15N NMR spectroscopy.
Journal of biomolecular NMR 2000;17(3):239-55.
2000: Graether S P; Kuiper M J; Gagné S M; Walker V K; Jia Z; Sykes B D; Davies P L
Beta-helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect.
Nature 2000;406(6793):325-8.
2000: Liou Y C; Daley M E; Graham L A; Kay C M; Walker V K; Sykes B D; Davies P L
Folding and structural characterization of highly disulfide-bonded beetle antifreeze protein produced in bacteria.
Protein expression and purification 2000;19(1):148-57.
2000: Keizer D W; Crump M P; Lee T W; Slupsky C M; Clark-Lewis I; Sykes B D
Human CC chemokine I-309, structural consequences of the additional disulfide bond.
Biochemistry 2000;39(20):6053-9.
2000: McInnes C; Kondejewski L H; Hodges R S; Sykes B D
Development of the structural basis for antimicrobial and hemolytic activities of peptides based on gramicidin S and design of novel analogs using NMR spectroscopy.
The Journal of biological chemistry 2000;275(19):14287-94.
2000: McInnes C; Grothe S; O'Connor-McCourt M; Sykes B D
NMR study of the differential contributions of residues of transforming growth factor alpha to association with its receptor.
Protein engineering 2000;13(3):143-7.
2000: Mercier P; Li M X; Sykes B D
Role of the structural domain of troponin C in muscle regulation: NMR studies of Ca2+ binding and subsequent interactions with regions 1-40 and 96-115 of troponin I.
Biochemistry 2000;39(11):2902-11.
2000: Lavigne P; Bagu J R; Boyko R; Willard L; Holmes C F; Sykes B D
Structure-based thermodynamic analysis of the dissociation of protein phosphatase-1 catalytic subunit and microcystin-LR docked complexes.
Protein science : a publication of the Protein Society 2000;9(2):252-64.
1999: Crump M P; Spyracopoulos L; Lavigne P; Kim K S; Clark-lewis I; Sykes B D
Backbone dynamics of the human CC chemokine eotaxin: fast motions, slow motions, and implications for receptor binding.
Protein science : a publication of the Protein Society 1999;8(10):2041-54.
1999: Li M X; Spyracopoulos L; Sykes B D
Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C.
Biochemistry 1999;38(26):8289-98.
1999: Rajarathnam K; Sykes B D; Dewald B; Baggiolini M; Clark-Lewis I
Disulfide bridges in interleukin-8 probed using non-natural disulfide analogues: dissociation of roles in structure from function.
Biochemistry 1999;38(24):7653-8.
1999: Tsuda S; Miura A; Gagné S M; Spyracopoulos L; Sykes B D
Low-temperature-induced structural changes in the Apo regulatory domain of skeletal muscle troponin C.
Biochemistry 1999;38(18):5693-700.
1999: Kondejewski L H; Jelokhani-Niaraki M; Farmer S W; Lix B; Kay C M; Sykes B D; Hancock R E; Hodges R S
Dissociation of antimicrobial and hemolytic activities in cyclic peptide diastereomers by systematic alterations in amphipathicity.
The Journal of biological chemistry 1999;274(19):13181-92.
1999: McKay R T; Tripet B P; Pearlstone J R; Smillie L B; Sykes B D
Defining the region of troponin-I that binds to troponin-C.
Biochemistry 1999;38(17):5478-89.
1999: Loewen M C; Chao H; Houston M E; Baardsnes J; Hodges R S; Kay C M; Sykes B D; Sönnichsen F D; Davies P L
Alternative roles for putative ice-binding residues in type I antifreeze protein.
Biochemistry 1999;38(15):4743-9.
1999: Rajarathnam K; Crump M P; Clark-Lewis I; Sykes B D
Spectroscopic characterization of chemokines: relevance for quality control and standardization.
Developments in biological standardization 1999;97():49-57.
1998: Spyracopoulos L; Gagné S M; Li M X; Sykes B D
Dynamics and thermodynamics of the regulatory domain of human cardiac troponin C in the apo- and calcium-saturated states.
Biochemistry 1998;37(51):18032-44.
1998: Loewen M C; Gronwald W; Sönnichsen F D; Sykes B D; Davies P L
The ice-binding site of sea raven antifreeze protein is distinct from the carbohydrate-binding site of the homologous C-type lectin.
Biochemistry 1998;37(51):17745-53.
1998: Gauthier S Y; Kay C M; Sykes B D; Walker V K; Davies P L
Disulfide bond mapping and structural characterization of spruce budworm antifreeze protein.
European journal of biochemistry / FEBS 1998;258(2):445-53.
1998: Gronwald W; Willard L; Jellard T; Boyko R F; Rajarathnam K; Wishart D S; Sönnichsen F D; Sykes B D
CAMRA: chemical shift based computer aided protein NMR assignments.
Journal of biomolecular NMR 1998;12(3):395-405.
1998: McInnes C; Wang J; Al Moustafa A E; Yansouni C; O'Connor-McCourt M; Sykes B D
Structure-based minimization of transforming growth factor-alpha (TGF-alpha) through NMR analysis of the receptor-bound ligand. Design, solution structure, and activity of TGF-alpha 8-50.
The Journal of biological chemistry 1998;273(42):27357-63.
1998: McKay R T; Pearlstone J R; Corson D C; Gagné S M; Smillie L B; Sykes B D
Structure and interaction site of the regulatory domain of troponin-C when complexed with the 96-148 region of troponin-I.
Biochemistry 1998;37(36):12419-30.
1998: Crump M P; Rajarathnam K; Kim K S; Clark-Lewis I; Sykes B D
Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation.
The Journal of biological chemistry 1998;273(35):22471-9.
1998: Lavigne P; Crump M P; Gagné S M; Hodges R S; Kay C M; Sykes B D
Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper.
Journal of molecular biology 1998;281(1):165-81.
1998: Weers P M; Wang J; Van der Horst D J; Kay C M; Sykes B D; Ryan R O
Recombinant locust apolipophorin III: characterization and NMR spectroscopy.
Biochimica et biophysica acta 1998;1393(1):99-107.
1998: Gagné S M; Tsuda S; Spyracopoulos L; Kay L E; Sykes B D
Backbone and methyl dynamics of the regulatory domain of troponin C: anisotropic rotational diffusion and contribution of conformational entropy to calcium affinity.
Journal of molecular biology 1998;278(3):667-86.
1998: Houston M E; Chao H; Hodges R S; Sykes B D; Kay C M; Sönnichsen F D; Loewen M C; Davies P L
Binding of an oligopeptide to a specific plane of ice.
The Journal of biological chemistry 1998;273(19):11714-8.
1998: Gibbs A C; Kondejewski L H; Gronwald W; Nip A M; Hodges R S; Sykes B D; Wishart D S
Unusual beta-sheet periodicity in small cyclic peptides.
Nature structural biology 1998;5(4):284-8.
1998: Gronwald W; Loewen M C; Lix B; Daugulis A J; Sönnichsen F D; Davies P L; Sykes B D
The solution structure of type II antifreeze protein reveals a new member of the lectin family.
Biochemistry 1998;37(14):4712-21.
1998: Wang J; Narayanaswami V; Sykes B D; Ryan R O
Interhelical contacts are required for the helix bundle fold of apolipophorin III and its ability to interact with lipoproteins.
Protein science : a publication of the Protein Society 1998;7(2):336-41.
1998: Gagné S M; Li M X; McKay R T; Sykes B D
The NMR angle on troponin C.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(2-3):302-12.
1998: Wang J; Sahoo D; Sykes B D; Ryan R O
NMR evidence for a conformational adaptation of apolipophorin III upon lipid association.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(2-3):276-83.
1997: Wishart D S; Watson M S; Boyko R F; Sykes B D
Automated 1H and 13C chemical shift prediction using the BioMagResBank.
Journal of biomolecular NMR 1997;10(4):329-36.
1997: Chao H; Houston M E; Hodges R S; Kay C M; Sykes B D; Loewen M C; Davies P L; Sönnichsen F D
A diminished role for hydrogen bonds in antifreeze protein binding to ice.
Biochemistry 1997;36(48):14652-60.
1997: Crump M P; Gong J H; Loetscher P; Rajarathnam K; Amara A; Arenzana-Seisdedos F; Virelizier J L; Baggiolini M; Sykes B D; Clark-Lewis I
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.
The EMBO journal 1997;16(23):6996-7007.
1997: McKay R T; Tripet B P; Hodges R S; Sykes B D
Interaction of the second binding region of troponin I with the regulatory domain of skeletal muscle troponin C as determined by NMR spectroscopy.
The Journal of biological chemistry 1997;272(45):28494-500.
1997: Tang X B; Dallaire P; Hoyt D W; Sykes B D; O'Connor-McCourt M; Malcolm B A
Construction of transforming growth factor alpha (TGF-alpha) phage library and identification of high binders of epidermal growth factor receptor (EGFR) by phage display.
Journal of biochemistry 1997;122(4):686-90.
1997: Li M X; Gagné S M; Spyracopoulos L; Kloks C P; Audette G; Chandra M; Solaro R J; Smillie L B; Sykes B D
NMR studies of Ca2+ binding to the regulatory domains of cardiac and E41A skeletal muscle troponin C reveal the importance of site I to energetics of the induced structural changes.
Biochemistry 1997;36(41):12519-25.
1997: Gronwald W; Boyko R F; Sykes B D
GSC: a graphical program for NMR chemical shift comparison.
Computer applications in the biosciences : CABIOS 1997;13(5):557-8.
1997: Campbell A P; Bautista D L; Tripet B; Wong W Y; Irvin R T; Hodges R S; Sykes B D
Solution secondary structure of a bacterially expressed peptide from the receptor binding domain of Pseudomonas aeruginosa pili strain PAK: A heteronuclear multidimensional NMR study.
Biochemistry 1997;36(42):12791-801.
1997: Spyracopoulos L; Li M X; Sia S K; Gagné S M; Chandra M; Solaro R J; Sykes B D
Calcium-induced structural transition in the regulatory domain of human cardiac troponin C.
Biochemistry 1997;36(40):12138-46.
1997: Sia S K; Li M X; Spyracopoulos L; Gagné S M; Liu W; Putkey J A; Sykes B D
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
The Journal of biological chemistry 1997;272(29):18216-21.
1997: Wang J; Gagné S M; Sykes B D; Ryan R O
Insight into lipid surface recognition and reversible conformational adaptations of an exchangeable apolipoprotein by multidimensional heteronuclear NMR techniques.
The Journal of biological chemistry 1997;272(29):17912-20.
1997: Pearlstone J R; Sykes B D; Smillie L B
Interactions of structural C and regulatory N domains of troponin C with repeated sequence motifs in troponin I.
Biochemistry 1997;36(24):7601-6.
1997: Gagné S M; Li M X; Sykes B D
Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins.
Biochemistry 1997;36(15):4386-92.
1997: Campbell A P; Wong W Y; Houston M; Schweizer F; Cachia P J; Irvin R T; Hindsgaul O; Hodges R S; Sykes B D
Interaction of the receptor binding domains of Pseudomonas aeruginosa pili strains PAK, PAO, KB7 and P1 to a cross-reactive antibody and receptor analog: implications for synthetic vaccine design.
Journal of molecular biology 1997;267(2):382-402.
1997: Bagu J R; Sykes B D; Craig M M; Holmes C F
A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A.
The Journal of biological chemistry 1997;272(8):5087-97.
1997: Rajarathnam K; Kay C M; Dewald B; Wolf M; Baggiolini M; Clark-Lewis I; Sykes B D
Neutrophil-activating peptide-2 and melanoma growth-stimulatory activity are functional as monomers for neutrophil activation.
The Journal of biological chemistry 1997;272(3):1725-9.
1997: McInnes C; Sykes B D
Growth factor receptors: structure, mechanism, and drug discovery.
Biopolymers 1997;43(5):339-66.
1997: Rajarathnam K; Kay C M; Clark-Lewis I; Sykes B D
Characterization of quaternary structure of interleukin-8 and functional implications.
Methods in enzymology 1997;287():89-105.
1997: Fisher C A; Wang J; Francis G A; Sykes B D; Kay C M; Ryan R O
Bacterial overexpression, isotope enrichment, and NMR analysis of the N-terminal domain of human apolipoprotein E.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1997;75(1):45-53.
1996: Gronwald W; Chao H; Reddy D V; Davies P L; Sykes B D; Sönnichsen F D
NMR characterization of side chain flexibility and backbone structure in the type I antifreeze protein at near freezing temperatures.
Biochemistry 1996;35(51):16698-704.
1996: Campbell A P; Sheth H; Hodges R S; Sykes B D
NMR solution structure of the receptor binding domain of Pseudomonas aeruginosa pilin strain P1. Identification of a beta-turn.
International journal of peptide and protein research 1996;48(6):539-52.
1996: Rajarathnam K; Clark-Lewis I; Dewald B; Baggiolini M; Sykes B D
1H NMR evidence that Glu-38 interacts with the N-terminal functional domain in interleukin-8.
FEBS letters 1996;399(1-2):43-6.
1996: McInnes C; Hoyt D W; Harkins R N; Pagila R N; Debanne M T; O'Connor-McCourt M; Sykes B D
NMR study of the transforming growth factor-alpha (TGF-alpha)-epidermal growth factor receptor complex. Visualization of human TGF-alpha binding determinants through nuclear Overhauser enhancement analysis.
The Journal of biological chemistry 1996;271(50):32204-11.
1996: Wang J; Breslow E; Sykes B D
Differential binding of desmopressin and vasopressin to neurophysin-II.
The Journal of biological chemistry 1996;271(49):31354-9.
1996: Sönnichsen F D; DeLuca C I; Davies P L; Sykes B D
Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
Structure (London, England : 1993) 1996;4(11):1325-37.
1996: DeLuca C I; Chao H; Sönnichsen F D; Sykes B D; Davies P L
Effect of type III antifreeze protein dilution and mutation on the growth inhibition of ice.
Biophysical journal 1996;71(5):2346-55.
1996: Kim K S; Rajarathnam K; Clark-Lewis I; Sykes B D
Structural characterization of a monomeric chemokine: monocyte chemoattractant protein-3.
FEBS letters 1996;395(2-3):277-82.
1996: Houston M E; Campbell A P; Lix B; Kay C M; Sykes B D; Hodges R S
Lactam bridge stabilization of alpha-helices: the role of hydrophobicity in controlling dimeric versus monomeric alpha-helices.
Biochemistry 1996;35(31):10041-50.
1996: Sykes B D
Application of NMR spectroscopy to muscle calcium-binding proteins.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1996;29(7):825-9.
1995: Campbell A P; McInnes C; Hodges R S; Sykes B D
Comparison of NMR solution structures of the receptor binding domains of Pseudomonas aeruginosa pili strains PAO, KB7, and PAK: implications for receptor binding and synthetic vaccine design.
Biochemistry 1995;34(50):16255-68.
1995: Slupsky C M; Sykes B D
NMR solution structure of calcium-saturated skeletal muscle troponin C.
Biochemistry 1995;34(49):15953-64.
1995: Rajarathnam K; Clark-Lewis I; Sykes B D
1H NMR solution structure of an active monomeric interleukin-8.
Biochemistry 1995;34(40):12983-90.
1995: Wong W Y; Campbell A P; McInnes C; Sykes B D; Paranchych W; Irvin R T; Hodges R S
Structure-function analysis of the adherence-binding domain on the pilin of Pseudomonas aeruginosa strains PAK and KB7.
Biochemistry 1995;34(40):12963-72.
1995: Wishart D S; Bigam C G; Yao J; Abildgaard F; Dyson H J; Oldfield E; Markley J L; Sykes B D
1H, 13C and 15N chemical shift referencing in biomolecular NMR.
Journal of biomolecular NMR 1995;6(2):135-40.
1995: Gagné S M; Tsuda S; Li M X; Smillie L B; Sykes B D
Structures of the troponin C regulatory domains in the apo and calcium-saturated states.
Nature structural biology 1995;2(9):784-9.
1995: Slupsky C M; Reinach F C; Smillie L B; Sykes B D
Solution secondary structure of calcium-saturated troponin C monomer determined by multidimensional heteronuclear NMR spectroscopy.
Protein science : a publication of the Protein Society 1995;4(7):1279-90.
1995: Li M X; Gagné S M; Tsuda S; Kay C M; Smillie L B; Sykes B D
Calcium binding to the regulatory N-domain of skeletal muscle troponin C occurs in a stepwise manner.
Biochemistry 1995;34(26):8330-40.
1995: Slupsky C M; Kay C M; Reinach F C; Smillie L B; Sykes B D
Calcium-induced dimerization of troponin C: mode of interaction and use of trifluoroethanol as a denaturant of quaternary structure.
Biochemistry 1995;34(22):7365-75.
1995: Clark-Lewis I; Kim K S; Rajarathnam K; Gong J H; Dewald B; Moser B; Baggiolini M; Sykes B D
Structure-activity relationships of chemokines.
Journal of leukocyte biology 1995;57(5):703-11.
1995: Wang J; Liu H; Sykes B D; Ryan R O
Identification and localization of two distinct microenvironments for the diacylglycerol component of lipophorin particles by 13C NMR.
Biochemistry 1995;34(20):6755-61.
1995: Wang J; Hodges R S; Sykes B D
Effect of trifluoroethanol on the solution structure and flexibility of desmopressin: a two-dimensional NMR study.
International journal of peptide and protein research 1995;45(5):471-81.
1995: Sönnichsen F D; Sykes B D; Davies P L
Comparative modeling of the three-dimensional structure of type II antifreeze protein.
Protein science : a publication of the Protein Society 1995;4(3):460-71.
1995: Zhang Y P; Lewis R N; Henry G D; Sykes B D; Hodges R S; McElhaney R N
Peptide models of helical hydrophobic transmembrane segments of membrane proteins. 1. Studies of the conformation, intrabilayer orientation, and amide hydrogen exchangeability of Ac-K2-(LA)12-K2-amide.
Biochemistry 1995;34(7):2348-61.
1995: Wishart D S; Bigam C G; Holm A; Hodges R S; Sykes B D
1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects.
Journal of biomolecular NMR 1995;5(1):67-81.
1994: Kim K S; Clark-Lewis I; Sykes B D
Solution structure of GRO/melanoma growth stimulatory activity determined by 1H NMR spectroscopy.
The Journal of biological chemistry 1994;269(52):32909-15.
1994: Hoyt D W; Harkins R N; Debanne M T; O'Connor-McCourt M; Sykes B D
Interaction of transforming growth factor alpha with the epidermal growth factor receptor: binding kinetics and differential mobility within the bound TGF-alpha.
Biochemistry 1994;33(51):15283-92.
1994: Wishart D S; Boyko R F; Sykes B D
Constrained multiple sequence alignment using XALIGN.
Computer applications in the biosciences : CABIOS 1994;10(6):687-8.
1994: Gagné S M; Tsuda S; Li M X; Chandra M; Smillie L B; Sykes B D
Quantification of the calcium-induced secondary structural changes in the regulatory domain of troponin-C.
Protein science : a publication of the Protein Society 1994;3(11):1961-74.
1994: Chao H; Sönnichsen F D; DeLuca C I; Sykes B D; Davies P L
Structure-function relationship in the globular type III antifreeze protein: identification of a cluster of surface residues required for binding to ice.
Protein science : a publication of the Protein Society 1994;3(10):1760-9.
1994: McInnes C; Kay C M; Hodges R S; Sykes B D
Conformational differences between cis and trans proline isomers of a peptide antigen representing the receptor binding domain of Pseudomonas aeruginosa as studied by 1H-NMR.
Biopolymers 1994;34(9):1221-30.
1994: Shaw G S; Hodges R S; Kay C M; Sykes B D
Relative stabilities of synthetic peptide homo- and heterodimeric troponin-C domains.
Protein science : a publication of the Protein Society 1994;3(7):1010-9.
1994: Rajarathnam K; Clark-Lewis I; Sykes B D
1H NMR studies of interleukin 8 analogs: characterization of the domains essential for function.
Biochemistry 1994;33(21):6623-30.
1994: Rajarathnam K; Sykes B D; Kay C M; Dewald B; Geiser T; Baggiolini M; Clark-Lewis I
Neutrophil activation by monomeric interleukin-8.
Science (New York, N.Y.) 1994;264(5155):90-2.
1994: Wishart D S; Boyko R F; Willard L; Richards F M; Sykes B D
SEQSEE: a comprehensive program suite for protein sequence analysis.
Computer applications in the biosciences : CABIOS 1994;10(2):121-32.
1994: Findlay W A; Sönnichsen F D; Sykes B D
Solution structure of the TR1C fragment of skeletal muscle troponin-C.
The Journal of biological chemistry 1994;269(9):6773-8.
1994: Wishart D S; Sykes B D
The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data.
Journal of biomolecular NMR 1994;4(2):171-80.
1994: Baleja J D; Sykes B D
A nuclear magnetic resonance study of the DNA-binding affinity of Cro repressor protein stabilized by a disulfide bond.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(3-4):95-108.
1994: Henry G D; Sykes B D
Methods to study membrane protein structure in solution.
Methods in enzymology 1994;239():515-35.
1994: Wishart D S; Sykes B D
Chemical shifts as a tool for structure determination.
Methods in enzymology 1994;239():363-92.
1993: McInnes C; Sönnichsen F D; Kay C M; Hodges R S; Sykes B D
NMR solution structure and flexibility of a peptide antigen representing the receptor binding domain of Pseudomonas aeruginosa.
Biochemistry 1993;32(49):13432-40.
1993: Henry G D; Maruta S; Ikebe M; Sykes B D
Observation of multiple myosin subfragment 1-ADP-fluoroberyllate complexes by 19F NMR spectroscopy.
Biochemistry 1993;32(39):10451-6.
1993: Chao H; Davies P L; Sykes B D; Sönnichsen F D
Use of proline mutants to help solve the NMR solution structure of type III antifreeze protein.
Protein science : a publication of the Protein Society 1993;2(9):1411-28.
1993: Zhou N E; Kay C M; Sykes B D; Hodges R S
A single-stranded amphipathic alpha-helix in aqueous solution: design, structural characterization, and its application for determining alpha-helical propensities of amino acids.
Biochemistry 1993;32(24):6190-7.
1993: Wishart D S; Sykes B D; Richards F M
Improved synthetic methods for the selective deuteration of aromatic amino acids: applications of selective protonation towards the identification of protein folding intermediates through nuclear magnetic resonance.
Biochimica et biophysica acta 1993;1164(1):36-46.
1993: Maruta S; Henry G D; Sykes B D; Ikebe M
Formation of the stable myosin-ADP-aluminum fluoride and myosin-ADP-beryllium fluoride complexes and their analysis using 19F NMR.
The Journal of biological chemistry 1993;268(10):7093-100.
1993: Findlay W A; Sykes B D
1H-NMR resonance assignments, secondary structure, and global fold of the TR1C fragment of turkey skeletal troponin C in the calcium-free state.
Biochemistry 1993;32(13):3461-7.
1993: Baleja J D; Buchko G W; Weinfeld M; Sykes B D
Characterization of gamma-radiation induced decomposition products of thymidine-containing dinucleoside monophosphates by nuclear magnetic resonance spectroscopy.
Journal of biomolecular structure & dynamics 1993;10(4):747-62.
1993: Sönnichsen F D; Sykes B D; Chao H; Davies P L
The nonhelical structure of antifreeze protein type III.
Science (New York, N.Y.) 1993;259(5098):1154-7.
1993: Campbell A P; Sykes B D
The two-dimensional transferred nuclear Overhauser effect: theory and practice.
Annual review of biophysics and biomolecular structure 1993;22():99-122.
1992: Slupsky C M; Shaw G S; Campbell A P; Sykes B D
A 1H NMR study of a ternary peptide complex that mimics the interaction between troponin C and troponin I.
Protein science : a publication of the Protein Society 1992;1(12):1595-603.
1992: Campbell A P; Van Eyk J E; Hodges R S; Sykes B D
Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C.
Biochimica et biophysica acta 1992;1160(1):35-54.
1992: Pearlstone J R; McCubbin W D; Kay C M; Sykes B D; Smillie L B
Spectroscopic analysis of a methionine-48 to tyrosine mutant of chicken troponin C.
Biochemistry 1992;31(40):9703-8.
1992: Shaw G S; Hodges R S; Sykes B D
Determination of the solution structure of a synthetic two-site calcium-binding homodimeric protein domain by NMR spectroscopy.
Biochemistry 1992;31(40):9572-80.
1992: Sönnichsen F D; Van Eyk J E; Hodges R S; Sykes B D
Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide.
Biochemistry 1992;31(37):8790-8.
1992: Wang J; Liu H; Sykes B D; Ryan R O
31P-NMR study of the phospholipid moiety of lipophorin subspecies.
Biochemistry 1992;31(37):8706-12.
1992: Monera O D; Shaw G S; Zhu B Y; Sykes B D; Kay C M; Hodges R S
Role of interchain alpha-helical hydrophobic interactions in Ca2+ affinity, formation, and stability of a two-site domain in troponin C.
Protein science : a publication of the Protein Society 1992;1(7):945-55.
1992: Henry G D; Sykes B D
Assignment of amide 1H and 15N NMR resonances in detergent-solubilized M13 coat protein: a model for the coat protein dimer.
Biochemistry 1992;31(23):5284-97.
1992: Shaw G S; Hodges R S; Sykes B D
Stoichiometry of calcium binding to a synthetic heterodimeric troponin-C domain.
Biopolymers 1992;32(4):391-7.
1991: Campbell A P; Sykes B D
Interaction of troponin I and troponin C. Use of the two-dimensional nuclear magnetic resonance transferred nuclear Overhauser effect to determine the structure of the inhibitory troponin I peptide when bound to skeletal troponin C.
Journal of molecular biology 1991;222(2):405-21.
1991: Baleja J D; Anderson W F; Sykes B D
Different interactions of Cro repressor dimer with the left and right halves of OR3 operator DNA.
The Journal of biological chemistry 1991;266(33):22115-24.
1991: Campbell A P; Sykes B D
Effects of internal motions on the development of the two-dimensional transferred nuclear Overhauser effect.
Journal of biomolecular NMR 1991;1(4):391-402.
1991: Campbell A P; Cachia P J; Sykes B D
Interaction of troponin I and troponin C: 19F NMR studies of the binding of the inhibitory troponin I peptide to turkey skeletal troponin C.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1991;69(9):674-81.
1991: Shaw G S; Hodges R S; Sykes B D
Probing the relationship between alpha-helix formation and calcium affinity in troponin C: 1H NMR studies of calcium binding to synthetic and variant site III helix-loop-helix peptides.
Biochemistry 1991;30(34):8339-47.
1991: Baleja J D; Sykes B D
Comparison of the structures of operator DNA free and in complex with lambda repressor.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1991;69(2-3):202-5.
1990: Baleja J D; Germann M W; van de Sande J H; Sykes B D
Solution conformation of purine-pyrimidine DNA octamers using nuclear magnetic resonance, restrained molecular dynamics and NOE-based refinement.
Journal of molecular biology 1990;215(3):411-28.
1990: Shaw G S; Hodges R S; Sykes B D
Calcium-induced peptide association to form an intact protein domain: 1H NMR structural evidence.
Science (New York, N.Y.) 1990;249(4966):280-3.
1990: Henry G D; Sykes B D
Hydrogen exchange kinetics in a membrane protein determined by 15N NMR spectroscopy: use of the INEPT experiment to follow individual amides in detergent-solubilized M13 coat protein.
Biochemistry 1990;29(26):6303-13.
1990: Baleja J D; Pon R T; Sykes B D
Solution structure of phage lambda half-operator DNA by use of NMR, restrained molecular dynamics, and NOE-based refinement.
Biochemistry 1990;29(20):4828-39.
1990: Marsden B J; Shaw G S; Sykes B D
Calcium binding proteins. Elucidating the contributions to calcium affinity from an analysis of species variants and peptide fragments.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1990;68(3):587-601.
1990: Henry G D; Sykes B D
Detergent-solubilized M13 coat protein exists as an asymmetric dimer. Observation of individual monomers by 15N, 13C and 1H nuclear magnetic resonance spectroscopy.
Journal of molecular biology 1990;212(1):11-4.
1990: Henry G D; Sykes B D
Structure and dynamics of detergent-solubilized M13 coat protein (an integral membrane protein) determined by 13C and 15N nuclear magnetic resonance spectroscopy.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1990;68(1):318-29.
1989: Golden L F; Corson D C; Sykes B D; Banville D; MacManus J P
Site-specific mutants of oncomodulin. 1H NMR and optical stopped-flow studies of the effect on the metal binding properties of an Asp59----Glu59 substitution in the calcium-specific site.
The Journal of biological chemistry 1989;264(34):20314-9.
1989: Marsden B J; Hodges R S; Sykes B D
A 1H NMR determination of the solution conformation of a synthetic peptide analogue of calcium-binding site III of rabbit skeletal troponin C.
Biochemistry 1989;28(22):8839-47.
1989: O'Neil J D; Sykes B D
Side-chain dynamics of a detergent-solubilized membrane protein: measurement of tryptophan and glutamine hydrogen-exchange rates in M13 coat protein by 1H NMR spectroscopy.
Biochemistry 1989;28(16):6736-45.
1989: MacManus J P; Hutnik C M; Sykes B D; Szabo A G; Williams T C; Banville D
Characterization and site-specific mutagenesis of the calcium-binding protein oncomodulin produced by recombinant bacteria.
The Journal of biological chemistry 1989;264(6):3470-7.
1989: O'Neil J D; Sykes B D
NMR studies of the influence of dodecyl sulfate on the amide hydrogen exchange kinetics of a micelle-solubilized hydrophobic tripeptide.
Biochemistry 1989;28(2):699-707.
1989: Campbell A P; Sykes B D
Conformation of a troponin-I peptide bound to troponin-C as determined by 1H NMR.
Advances in experimental medicine and biology 1989;255():195-204.
1988: Sanders C; Sykes B D; Smillie L B
Comparison of the structure and dynamics of chicken gizzard and rabbit cardiac tropomyosins: 1H NMR spectroscopy and measurement of amide hydrogen exchange rates.
Biochemistry 1988;27(18):7000-8.
1988: Marsden B J; Hodges R S; Sykes B D
1H-NMR studies of synthetic peptide analogues of calcium-binding site III of rabbit skeletal troponin C: effect on the lanthanum affinity of the interchange of aspartic acid and asparagine residues at the metal ion coordinating positions.
Biochemistry 1988;27(11):4198-206.
1988: O'Neil J D; Sykes B D
Structure and dynamics of a detergent-solubilized membrane protein: measurement of amide hydrogen exchange rates in M13 coat protein by 1H NMR spectroscopy.
Biochemistry 1988;27(8):2753-62.
1988: Lewis R N; Sykes B D; McElhaney R N
Thermotropic phase behavior of model membranes composed of phosphatidylcholines containing cis-monounsaturated acyl chain homologues of oleic acid: differential scanning calorimetric and 31P NMR spectroscopic studies.
Biochemistry 1988;27(3):880-7.
1987: Lewis R N; Sykes B D; McElhaney R N
Thermotropic phase behavior of model membranes composed of phosphatidylcholines containing dl-methyl anteisobranched fatty acids. 1. Differential scanning calorimetric and 31P NMR spectroscopic studies.
Biochemistry 1987;26(13):4036-44.
1987: Henry G D; Weiner J H; Sykes B D
Backbone dynamics of a model membrane protein: measurement of individual amide hydrogen-exchange rates in detergent-solubilized M13 coat protein using 13C NMR hydrogen/deuterium isotope shifts.
Biochemistry 1987;26(12):3626-34.
1987: Henry G D; Weiner J H; Sykes B D
Backbone dynamics of a model membrane protein: assignment of the carbonyl carbon 13C NMR resonances in detergent-solubilized M13 coat protein.
Biochemistry 1987;26(12):3619-26.
1987: Williams T C; Corson D C; Sykes B D; MacManus J P
Oncomodulin. 1H NMR and optical stopped-flow spectroscopic studies of its solution conformation and metal-binding properties.
The Journal of biological chemistry 1987;262(13):6248-56.
1987: Weiner J H; Dettman H D; Henry G D; O'Neil J D; Sykes B D
Nuclear magnetic resonance studies of a model membrane protein (M13 coat protein) reconstituted in detergent micelles and phospholipid vesicles.
Biochemical Society transactions 1987;15(1):81-5.
1986: Williams T C; Corson D C; Oikawa K; McCubbin W D; Kay C M; Sykes B D
1H NMR spectroscopic studies of calcium-binding proteins. 3. Solution conformations of rat apo-alpha-parvalbumin and metal-bound rat alpha-parvalbumin.
Biochemistry 1986;25(7):1835-46.
1986: Williams T C; Corson D C; McCubbin W D; Oikawa K; Kay C M; Sykes B D
1H NMR spectroscopic studies of calcium-binding proteins. 2. Histidine microenvironments in alpha- and beta-parvalbumins as determined by protonation and laser photochemically induced dynamic nuclear polarization effects.
Biochemistry 1986;25(7):1826-34.
1986: Corson D C; Williams T C; Kay L E; Sykes B D
1H NMR spectroscopic studies of calcium-binding proteins. 1. Stepwise proteolysis of the C-terminal alpha-helix of a helix-loop-helix metal-binding domain.
Biochemistry 1986;25(7):1817-26.
1986: Henry G D; Weiner J H; Sykes B D
Backbone dynamics of a model membrane protein: 13C NMR spectroscopy of alanine methyl groups in detergent-solubilized M13 coat protein.
Biochemistry 1986;25(3):590-8.
1986: Henry G D; O'Neil J D; Weiner J H; Sykes B D
Hydrogen exchange in the hydrophilic regions of detergent-solubilized M13 coat protein detected by 13C nuclear magnetic resonance isotope shifts.
Biophysical journal 1986;49(1):329-31.
1983: Corson D C; Williams T C; Sykes B D
Calcium binding proteins: optical stopped-flow and proton nuclear magnetic resonance studies of the binding of the lanthanide series of metal ions to parvalbumin.
Biochemistry 1983;22(25):5882-9.

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