FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Nancy Bonini

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Co-author Network

Publications

TOP 3
Yanshan Fang; Lorena Soares; Nancy M Bonini
Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing.
Masashi Abe; Nancy M Bonini
MicroRNAs and neurodegeneration: role and impact.
Yanshan Fang; Melissa Geary; Lorena Soares; Xiuyin Teng; Nancy M Bonini
A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Nancy Bonini (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yanshan Fang; Lorena Soares; Nancy M Bonini
Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing.
Nature protocols 2013;8(4):810-9.
2013: Masashi Abe; Nancy M Bonini
MicroRNAs and neurodegeneration: role and impact.
Trends in cell biology 2013;23(1):30-6.
2012: Yanshan Fang; Melissa Geary; Lorena Soares; Xiuyin Teng; Nancy M Bonini
A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity.
Current biology : CB 2012;22(7):590-5.
2012: Nan Liu; Li-San Wang; Yongqing Zhu; Masashi Abe; Kajia Cao; Gert-Jan Hendriks; Jason R Kennerdell; Michael Landreh; Nancy M Bonini
The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.
Nature 2012;482(7386):519-23.
2012: Yanshan Fang; Nancy M Bonini
Axon degeneration and regeneration: insights from Drosophila models of nerve injury.
Annual review of cell and developmental biology 2012;28():575-97.
2011: Leeanne McGurk; Nancy M Bonini
Cell biology. Yeast informs Alzheimer's disease.
Science (New York, N.Y.) 2011;334(6060):1212-3.
2011: Nan Liu; Ammar S Naqvi; Leah R Sabin; Zhenming Yu; Masashi Abe; Sara Cherry; Gert-Jan Hendriks; Nancy M Bonini
The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila.
Current biology : CB 2011;21(22):1888-93.
2011: Nancy M Bonini; Aaron D Gitler
Model organisms reveal insight into human neurodegenerative disease: ataxin-2 intermediate-length polyglutamine expansions are a risk factor for ALS.
Journal of molecular neuroscience : MN 2011;45(3):676-83.
2011: T Lee; Y R Li; D Ramos; Nancy M Bonini; A Chesi; J Epstein; M P Hart; B Hodges; D Hosangadi; N Jethava; Aaron D Gitler
Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis.
Neurology 2011;76(24):2062-5.
2011: Zhenming Yu; Xiuyin Teng; Nancy M Bonini
Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy.
PLoS genetics 2011;7(3):e1001340.
2011: Zhenming Yu; Nancy M Bonini
Modeling human trinucleotide repeat diseases in Drosophila.
International review of neurobiology 2011;99():191-212.
2011: Zhenming Yu; Yongqing Zhu; Alice S Chen-Plotkin; Dana Clay-Falcone; Leo McCluskey; Lauren B Elman; Robert G Kalb; John Q Trojanowski; Virginia M-Y Lee; Vivianna M Van Deerlin; Aaron D Gitler; Nancy M Bonini
PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats.
PloS one 2011;6(3):e17951.
2011: Joonil Jung; Marijn T M van Jaarsveld; Shin-Yi Shieh; Kexiang Xu; Nancy M Bonini
Defining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogaster.
Genetics 2011;187(1):61-71.
2010: Andrew C Elden; Hyung-Jun Kim; Michael P Hart; Alice S Chen-Plotkin; Brian S Johnson; Xiaodong Fang; Maria Armakola; Felix Geser; Robert Greene; Min Min Lu; Arun Padmanabhan; Dana Clay-Falcone; Leo McCluskey; Lauren Elman; Denise Juhr; Peter J Gruber; Udo Rüb; Georg Auburger; John Q Trojanowski; Virginia M-Y Lee; Vivianna M Van Deerlin; Nancy M Bonini; Aaron D Gitler
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
Nature 2010;466(7310):1069-75.
2010: Ling-Yang Hao; Benoit I Giasson; Nancy M Bonini
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(21):9747-52.
2009: Joonil Jung; K Xu; Derek Lessing; Nancy M Bonini
Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3.
Human molecular genetics 2009;18(24):4843-52.
2009: Derek Lessing; Nancy M Bonini
Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants.
Nature reviews. Genetics 2009;10(6):359-70.
2008: Nancy M Bonini
A tribute to Seymour Benzer, 1921--2007.
Genetics 2008;180(3):1265-73.
2008: Melanie R Watson; Robert D Lagow; Kexiang Xu; Bing Zhang; Nancy M Bonini
A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1.
The Journal of biological chemistry 2008;283(36):24972-81.
2008: Marcel van der Brug; Jeff Blackinton; Jayanth Chandran; Ling-Yang Hao; Ashish Lal; Krystyna Mazan-Mamczarz; Jennifer L Martindale; Chengsong Xie; Rili Ahmad; Kelly J Thomas; Alexandra Beilina; J Raphael Gibbs; Jinhui Ding; Amanda Myers; Ming Zhan; Huaibin Cai; Nancy M Bonini; Myriam Gorospe; Mark Cookson
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10244-9.
2008: Ling-Bo Li; Zhenming Yu; Xiuyin Teng; Nancy M Bonini
RNA toxicity is a component of ataxin-3 degeneration in Drosophila.
Nature 2008;453(7198):1107-11.
2008: Derek Lessing; Nancy M Bonini
Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila.
PLoS biology 2008;6(2):e29.
2007: Ling-Bo Li; Kexiang Xu; Nancy M Bonini
Suppression of polyglutamine toxicity by the yeast Sup35 prion domain in Drosophila.
The Journal of biological chemistry 2007;282(52):37694-701.
2007: Julide Bilen; Nancy M Bonini
Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila.
PLoS genetics 2007;3(10):1950-64.
2007: Joonil Jung; Nancy M Bonini
CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease.
Science (New York, N.Y.) 2007;315(5820):1857-9.
2006: Nan Liu; Nancy M Bonini
Hosting neurotoxicity in polyglutamine disease.
Cell 2006;127(7):1299-300.
2006: Julide Bilen; Nan Liu; Nancy M Bonini
A new role for microRNA pathways: modulation of degeneration induced by pathogenic human disease proteins.
Cell cycle (Georgetown, Tex.) 2006;5(24):2835-8.
2006: Julide Bilen; Nan Liu; Barrington Burnett; Randall N Pittman; Nancy M Bonini
MicroRNA pathways modulate polyglutamine-induced neurodegeneration.
Molecular cell 2006;24(1):157-63.
2006: Marc C Meulener; Kexiang Xu; Leonor Thomson; Leonor Thompson; Harry Ischiropoulos; Nancy M Bonini
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12517-22.
2006: Antony A Cooper; Aaron D Gitler; Anil Govind Cashikar; Cole Haynes; Kathryn J Hill; Bhupinder Bhullar; Kangning Liu; Kexiang Xu; Katherine E Strathearn; Fang Liu; Songsong Cao; Kim A Caldwell; Guy A Caldwell; Gerald Marsischky; Richard D Kolodner; Joshua LaBaer; Jean-Christophe Rochet; Nancy M Bonini; Susan Lindquist
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.
Science (New York, N.Y.) 2006;313(5785):324-8.
2006: Annett Boeddrich; Sébastien Gaumer; Annette Haacke; Nikolay Tzvetkov; Mario Albrecht; Bernd Evert; Eva-Christina Müller; Rudi Lurz; Peter Breuer; Nancy Schugardt; Stephanie Plassmann; Kexiang Xu; John M Warrick; Jaana Suopanki; Ullrich Wüllner; Ronald Frank; Ulrich F Hartl; Nancy M Bonini; Erich E Wanker
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
The EMBO journal 2006;25(7):1547-58.
2006: Kunihiro Uryu; Christiane Richter-Landsberg; William Welch; Eveline Sun; Olaf Goldbaum; Erin H Norris; Chi-Tuan Pham; Ikuru Yazawa; Kristen Hilburger; Matthew Micsenyi; Benoit I Giasson; Nancy M Bonini; Virginia M-Y Lee; John Q Trojanowski
Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies.
The American journal of pathology 2006;168(3):947-61.
2006: Benoit I Giasson; Jason P Covy; Nancy M Bonini; Howard I Hurtig; Matthew J Farrer; John Q Trojanowski; Vivianna M Van Deerlin
Biochemical and pathological characterization of Lrrk2.
Annals of neurology 2006;59(2):315-22.
2005: Nancy M Bonini; Albert R La Spada
Silencing polyglutamine degeneration with RNAi.
Neuron 2005;48(5):715-8.
2005: Nancy M Bonini; Benoit I Giasson
Snaring the function of alpha-synuclein.
Cell 2005;123(3):359-61.
2005: Marc C Meulener; Alexander J Whitworth; Cecilia E Armstrong-Gold; Patrizia Rizzu; Peter Heutink; Paul D Wes; Leo J Pallanck; Nancy M Bonini
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.
Current biology : CB 2005;15(17):1572-7.
2005: Marc C Meulener; Charles L Graves; Deepak M Sampathu; Cecilia E Armstrong-Gold; Nancy M Bonini; Benoit I Giasson
DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein.
Journal of neurochemistry 2005;93(6):1524-32.
2005: John M Warrick; Lance M Morabito; Julide Bilen; Beth Gordesky-Gold; Lynn Z Faust; Henry L Paulson; Nancy M Bonini
Ataxin-3 suppresses polyglutamine neurodegeneration in Drosophila by a ubiquitin-associated mechanism.
Molecular cell 2005;18(1):37-48.
2005: Pavan K Auluck; Marc C Meulener; Nancy M Bonini
Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.
The Journal of biological chemistry 2005;280(4):2873-8.
2005: Julide Bilen; Nancy M Bonini
Drosophila as a model for human neurodegenerative disease.
Annual review of genetics 2005;39():153-71.
2003: Shermali Gunawardena; Lu-Shiun Her; Richard G Brusch; Robert A Laymon; Ingrid R Niesman; Beth Gordesky-Gold; Louis Sintasath; Nancy M Bonini; Lawrence S B Goldstein
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila.
Neuron 2003;40(1):25-40.
2003: Lakshmi Atchison; Ayesha Ghias; Frank Wilkinson; Nancy M Bonini; Michael L Atchison
Transcription factor YY1 functions as a PcG protein in vivo.
The EMBO journal 2003;22(6):1347-58.
2003: Nancy M Bonini; Mark E Fortini
Human neurodegenerative disease modeling using Drosophila.
Annual review of neuroscience 2003;26():627-56.
2003: H Y Edwin Chan; Nancy M Bonini
Drosophila models of polyglutamine diseases.
Methods in molecular biology (Clifton, N.J.) 2003;217():241-51.
2002: Nancy M Bonini
Chaperoning brain degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99 Suppl 4():16407-11.
2002: Pavan K Auluck; Nancy M Bonini
Pharmacological prevention of Parkinson disease in Drosophila.
Nature medicine 2002;8(11):1185-6.
2002: H Y Edwin Chan; John M Warrick; Isabella Andriola; Diane E Merry; Nancy M Bonini
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila.
Human molecular genetics 2002;11(23):2895-904.
2002: Pavan K Auluck; H Y Edwin Chan; John Q Trojanowski; Virginia M-Y Lee; Nancy M Bonini
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease.
Science (New York, N.Y.) 2002;295(5556):865-8.
2001: Nancy M Bonini
Stores to die for.
Developmental cell 2001;1(4):447-8.
2000: H Y Edwin Chan; John M Warrick; GL Gray-Board; Henry L Paulson; Nancy M Bonini
Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.
Human molecular genetics 2000;9(19):2811-20.
2000: Henry L Paulson; Nancy M Bonini; K A Roth
Polyglutamine disease and neuronal cell death.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):12957-8.
2000: H Y Chan; Nancy M Bonini
Drosophila models of human neurodegenerative disease.
Cell death and differentiation 2000;7(11):1075-80.
2000: Quang T Bui; John E Zimmerman; H Liu; Nancy M Bonini
Molecular analysis of Drosophila eyes absent mutants reveals features of the conserved Eya domain.
Genetics 2000;155(2):709-20.
2000: Quang T Bui; John E Zimmerman; H Liu; GL Gray-Board; Nancy M Bonini
Functional analysis of an eye enhancer of the Drosophila eyes absent gene: differential regulation by eye specification genes.
Developmental biology 2000;221(2):355-64.
2000: Mark E Fortini; Nancy M Bonini
Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.
Trends in genetics : TIG 2000;16(4):161-7.
2000: Nancy M Bonini
Methods to detect patterns of cell death in Drosophila.
Methods in molecular biology (Clifton, N.J.) 2000;136():115-21.
2000: Nancy M Bonini
Drosophila as a genetic tool to define vertebrate pathway players.
Methods in molecular biology (Clifton, N.J.) 2000;136():7-14.
2000: John E Zimmerman; Quang T Bui; H Liu; Nancy M Bonini
Molecular genetic analysis of Drosophila eyes absent mutants reveals an eye enhancer element.
Genetics 2000;154(1):237-46.
1999: John M Warrick; H Y Edwin Chan; GL Gray-Board; Y Chai; Henry L Paulson; Nancy M Bonini
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.
Nature genetics 1999;23(4):425-8.
1999: Nancy M Bonini; Mark E Fortini
Surviving Drosophila eye development: integrating cell death with differentiation during formation of a neural structure.
BioEssays : news and reviews in molecular, cellular and developmental biology 1999;21(12):991-1003.
1999: Y Chai; SL Koppenhafer; Nancy M Bonini; Henry L Paulson
Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(23):10338-47.
1999: Nancy M Bonini
A genetic model for human polyglutamine-repeat disease in Drosophila melanogaster.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1386):1057-60.
1998: MK Perez; Henry L Paulson; S J Pendse; S J Saionz; Nancy M Bonini; Randall N Pittman
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation.
The Journal of cell biology 1998;143(6):1457-70.
1998: John M Warrick; Henry L Paulson; GL Gray-Board; Quang T Bui; Kenneth H Fischbeck; Randall N Pittman; Nancy M Bonini
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.
Cell 1998;93(6):939-49.
1998: W M Leiserson; Seymour Benzer; Nancy M Bonini
Dual functions of the Drosophila eyes absent gene in the eye and embryo.
Mechanisms of development 1998;73(2):193-202.
1998: Nancy M Bonini; W M Leiserson; Seymour Benzer
Multiple roles of the eyes absent gene in Drosophila.
Developmental biology 1998;196(1):42-57.
1997: Nancy M Bonini; Quang T Bui; GL Gray-Board; John M Warrick
The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates.
Development (Cambridge, England) 1997;124(23):4819-26.
1997: M Boyle; Nancy M Bonini; Stephen DiNardo
Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm.
Development (Cambridge, England) 1997;124(5):971-82.
1997: John E Zimmerman; Quang T Bui; E Steingrímsson; D L Nagle; W Fu; Anna Genin; Nancy B Spinner; Neal G Copeland; N A Jenkins; Maja Bucan; Nancy M Bonini
Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.
Genome research 1997;7(2):128-41.
1997: Nancy M Bonini
Surviving Drosophila eye development.
Cell death and differentiation 1997;4(1):4-11.
1995: Nancy M Bonini; K W Choi
Early decisions in Drosophila eye morphogenesis.
Current opinion in genetics & development 1995;5(4):507-15.
1994: W M Leiserson; Nancy M Bonini; Seymour Benzer
Transvection at the eyes absent gene of Drosophila.
Genetics 1994;138(4):1171-9.
1993: Nancy M Bonini; W M Leiserson; Seymour Benzer
The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.
Cell 1993;72(3):379-95.
1991: Nancy M Bonini; T C Evans; L A Miglietta; David L Nelson
The regulation of ciliary motility in Paramecium by Ca2+ and cyclic nucleotides.
Advances in second messenger and phosphoprotein research 1991;23():227-72.
1990: Nancy M Bonini; David L Nelson
Phosphoproteins associated with cyclic nucleotide stimulation of ciliary motility in Paramecium.
Journal of cell science 1990;95 ( Pt 2)():219-30.
1988: Nancy M Bonini; D L Nelson
Differential regulation of Paramecium ciliary motility by cAMP and cGMP.
The Journal of cell biology 1988;106(5):1615-23.
1986: Nancy M Bonini; M C Gustin; D L Nelson
Regulation of ciliary motility by membrane potential in Paramecium: a role for cyclic AMP.
Cell motility and the cytoskeleton 1986;6(3):256-72.
1983: Bruce Tempel; Nancy M Bonini; D R Dawson; W G Quinn
Reward learning in normal and mutant Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(5):1482-6.