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Gyongyi Szabo
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50
Mandrekar, Pranoti
35
Dolganiuc, Angela
31
Kodys, Karen
27
Catalano, Donna
10
Velayudham, Arumugam
9
Romics, László
8
Miller-Graziano, Carol
5
Kurt-Jones, Evelyn
5
Oak, Shilpa
4
Norkina, Oxana
4
Drechsler, Yvonne
3
Chang, Serena
3
Bellerose, Gary
3
Bakis, Gennadiy
3
Marshall, Christopher
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All Publications
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2009: Broering Teresa J; Garrity Kerry A; Boatright Naomi K; Sloan Susan E; Sandor Frantisek; Thomas William D; Szabo Gyongyi; Finberg Robert W; Ambrosino Donna M; Babcock Gregory J
Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.
Journal of virology 2009;83(23):12473-82.
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2009: Dolganiuc Angela; Petrasek Jan; Kodys Karen; Catalano Donna; Mandrekar Pranoti; Velayudham Arumugam; Szabo Gyongyi
MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice.
Alcoholism, clinical and experimental research 2009;33(10):1704-10.
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2009: Mandrekar Pranoti; Bala Shashi; Catalano Donna; Kodys Karen; Szabo Gyongyi
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1320-7.
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2009: Mandrekar Pranoti; Szabo Gyongyi
Signalling pathways in alcohol-induced liver inflammation.
Journal of hepatology 2009;50(6):1258-66.
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2009: Nath Bharath; Szabo Gyongyi
Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity.
Seminars in liver disease 2009;29(2):166-77.
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2009: Dolganiuc Angela; Szabo Gyongyi
In vitro and in vivo models of acute alcohol exposure.
World journal of gastroenterology : WJG 2009;15(10):1168-77.
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2009: Velayudham Arumugam; Dolganiuc Angela; Ellis Michael; Petrasek Jan; Kodys Karen; Mandrekar Pranoti; Szabo Gyongyi
VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
Hepatology (Baltimore, Md.) 2009;49(3):989-97.
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2009: Szabo Gyongyi
The "health" and future of the physician-scientist in hepatology.
Hepatology (Baltimore, Md.) 2009;49(2):341-3.
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2009: Szabo Gyongyi; Mandrekar Pranoti
A recent perspective on alcohol, immunity, and host defense.
Alcoholism, clinical and experimental research 2009;33(2):220-32.
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2009: Lau Audrey H; Szabo Gyongyi; Thomson Angus W
Antigen-presenting cells under the influence of alcohol.
Trends in immunology 2009;30(1):13-22.
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2008: Hritz Istvan; Velayudham Arumugam; Dolganiuc Angela; Kodys Karen; Mandrekar Pranoti; Kurt-Jones Evelyn; Szabo Gyongyi
Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion.
Hepatology (Baltimore, Md.) 2008;48(4):1342-7.
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2008: Hritz Istvan; Mandrekar Pranoti; Velayudham Arumugam; Catalano Donna; Dolganiuc Angela; Kodys Karen; Kurt-Jones Evelyn; Szabo Gyongyi
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
Hepatology (Baltimore, Md.) 2008;48(4):1224-31.
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2008: Norkina Oxana; Dolganiuc Angela; Catalano Donna; Kodys Karen; Mandrekar Pranoti; Syed Amber; Efros Marian; Szabo Gyongyi
Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.
Alcoholism, clinical and experimental research 2008;32(9):1565-73.
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2008: Dolganiuc Angela; Szabo Gyongyi
T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't.
Journal of leukocyte biology 2008;84(3):614-22.
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2008: Szabo Gyongyi; Dolganiuc Angela
Hepatitis C and innate immunity: recent advances.
Clinics in liver disease 2008;12(3):675-92, x.
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2008: Szabo Gyongyi; Dolganiuc Angela
Hepatitis C core protein - the "core" of immune deception?
Journal of hepatology 2008;48(1):8-11.
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2008: Szabo Gyongyi; Mandrekar Pranoti
Human monocytes, macrophages, and dendritic cells: alcohol treatment methods.
Methods in molecular biology (Clifton, N.J.) 2008;447():113-24.
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2008: Szabo Gyongyi; Dolganiuc Angela
The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity.
Critical reviews in immunology 2008;28(1):61-94.
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2007: Szabo Gyongyi; Mandrekar Pranoti; Dolganiuc Angela
Innate immune response and hepatic inflammation.
Seminars in liver disease 2007;27(4):339-50.
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2007: Dolganiuc Angela; Norkina Oxana; Kodys Karen; Catalano Donna; Bakis Gennadiy; Marshall Christopher; Mandrekar Pranoti; Szabo Gyongyi
Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection.
Gastroenterology 2007;133(5):1627-36.
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2007: Szabo Gyongyi; Chang Serena; Dolganiuc Angela
Altered innate immunity in chronic hepatitis C infection: cause or effect?
Hepatology (Baltimore, Md.) 2007;46(4):1279-90.
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2007: Chang Serena; Dolganiuc Angela; Szabo Gyongyi
Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
Journal of leukocyte biology 2007;82(3):479-87.
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2007: Norkina Oxana; Dolganiuc Angela; Shapiro Taryn; Kodys Karen; Mandrekar Pranoti; Szabo Gyongyi
Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes.
Journal of leukocyte biology 2007;82(3):752-62.
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2007: Mandrekar Pranoti; Jeliazkova Valentina; Catalano Donna; Szabo Gyongyi
Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7686-93.
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2007: Szabo Gyongyi; Dolganiuc Angela; Dai Qun; Pruett Stephen B
TLR4, ethanol, and lipid rafts: a new mechanism of ethanol action with implications for other receptor-mediated effects.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(3):1243-9.
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2007: Szabo Gyongyi; Mandrekar Pranoti; Oak Shilpa; Mayerle Julia
Effect of ethanol on inflammatory responses. Implications for pancreatitis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2007;7(2-3):115-23.
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2006: Velayudham Arumugam; Hritz Istvan; Dolganiuc Angela; Mandrekar Pranoti; Kurt-Jones Evelyn; Szabo Gyongyi
Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury.
Journal of hepatology 2006;45(6):813-24.
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2006: Szabo Gyongyi; Dolganiuc Angela
HCV immunopathogenesis: virus-induced strategies against host immunity.
Clinics in liver disease 2006;10(4):753-71.
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2006: Dolganiuc Angela; Chang Serena; Kodys Karen; Mandrekar Pranoti; Bakis Gennadiy; Cormier Maureen; Szabo Gyongyi
Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6758-68.
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2006: Drechsler Yvonne; Dolganiuc Angela; Norkina Oxana; Romics Laszlo; Li Weibo; Kodys Karen; Bach Fritz H; Mandrekar Pranoti; Szabo Gyongyi
Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2592-600.
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2006: Szabo Gyongyi; Dolganiuc Angela; Mandrekar Pranoti
Pattern recognition receptors: a contemporary view on liver diseases.
Hepatology (Baltimore, Md.) 2006;44(2):287-98.
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2006: Oak Shilpa; Mandrekar Pranoti; Catalano Donna; Kodys Karen; Szabo Gyongyi
TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7628-35.
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2006: Crews Fulton T; Bechara Rabih; Brown Lou Ann; Guidot David M; Mandrekar Pranoti; Oak Shilpa; Qin Liya; Szabo Gyongyi; Wheeler Michael; Zou Jian
Cytokines and alcohol.
Alcoholism, clinical and experimental research 2006;30(4):720-30.
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2006: Szabo Gyongyi; Aloman Costica; Polyak Stephen J; Weinman Steven A; Wands Jack; Zakhari Sam
Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity.
Alcoholism, clinical and experimental research 2006;30(4):709-19.
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2006: Dolganiuc Angela; Garcia Catherine; Kodys Karen; Szabo Gyongyi
Distinct Toll-like receptor expression in monocytes and T cells in chronic HCV infection.
World journal of gastroenterology : WJG 2006;12(8):1198-204.
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2006: Mandrekar Pranoti; Catalano Donna; White Bernadette; Szabo Gyongyi
Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10.
Alcoholism, clinical and experimental research 2006;30(1):135-9.
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2006: Dolganiuc Angela; Bakis Genadyi; Kodys Karen; Mandrekar Pranoti; Szabo Gyongyi
Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts.
Alcoholism, clinical and experimental research 2006;30(1):76-85.
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2005: Romics Laszlo; Dolganiuc Angela; Velayudham Arumugam; Kodys Karen; Mandrekar Pranoti; Golenbock Douglas; Kurt-Jones Evelyn; Szabo Gyongyi
Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
Journal of leukocyte biology 2005;78(6):1255-64.
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2005: Szabo Gyongyi; Velayudham Arumugam; Romics Laszlo; Mandrekar Pranoti
Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4.
Alcoholism, clinical and experimental research 2005;29(11 Suppl):140S-145S.
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2005: Szabo Gyongyi; Hoek Jan B; Darley-Usmar Victor; Hajnoczky Gyorgy; Knudsen Thomas; Mochly-Rosen Daria; Zakhari Sam
RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death.
Alcoholism, clinical and experimental research 2005;29(9):1749-52.
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2005: Mandrekar Pranoti; Pruett Stephen; Arteel Gavin; Thiele Geoffrey; Szabo Gyongyi
RSA 2004: combined basic research satellite symposium - session two: toll-like receptors and organ damage.
Alcoholism, clinical and experimental research 2005;29(9):1744-8.
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2005: Romics Laszlo; Mandrekar Pranoti; Kodys Karen; Velayudham Arumugam; Drechsler Yvonne; Dolganiuc Angela; Szabo Gyongyi
Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression.
Alcoholism, clinical and experimental research 2005;29(6):1018-26.
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2005: Szabo Gyongyi; Dolganiuc Angela
Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection.
Immunobiology 2005;210(2-4):237-47.
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2004: Dolganiuc Angela; Oak Shilpa; Kodys Karen; Golenbock Douglas T; Finberg Robert W; Kurt-Jones Evelyn; Szabo Gyongyi
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
Gastroenterology 2004;127(5):1513-24.
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2004: Romics Laszlo; Dolganiuc Angela; Kodys Karen; Drechsler Yvonne; Oak Shilpa; Velayudham Arumugam; Mandrekar Pranoti; Szabo Gyongyi
Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice.
Hepatology (Baltimore, Md.) 2004;40(3):555-64.
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2004: Mandrekar Pranoti; Catalano Donna; Dolganiuc Angela; Kodys Karen; Szabo Gyongyi
Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3398-407.
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2004: Romics Laszlo; Kodys Karen; Dolganiuc Angela; Graham Lucia; Velayudham Arumugam; Mandrekar Pranoti; Szabo Gyongyi
Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver.
Hepatology (Baltimore, Md.) 2004;40(2):376-85.
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2004: Szabo Gyongyi; Dolganiuc Angela; Mandrekar Pranoti; White Bernadette
Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infection.
Alcohol (Fayetteville, N.Y.) 2004;33(3):241-9.
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2004: Szabo Gyongyi; Catalano Donna; White Bernadette; Mandrekar Pranoti
Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells.
Alcoholism, clinical and experimental research 2004;28(5):824-8.
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2003: Dolganiuc Angela; Kodys Karen; Kopasz Andrea; Marshall Christopher; Mandrekar Pranoti; Szabo Gyongyi
Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction.
Alcoholism, clinical and experimental research 2003;27(6):1023-31.
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2003: Dolganiuc Angela; Kodys Karen; Kopasz Andrea; Marshall Christopher; Do Twan; Romics Laszlo; Mandrekar Pranoti; Zapp Maria; Szabo Gyongyi
Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(11):5615-24.
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2003: Szabo Gyongyi
Pathogenic interactions between alcohol and hepatitis C.
Current gastroenterology reports 2003;5(1):86-92.
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2002: Mandrekar Pranoti; Bellerose Gary; Szabo Gyongyi
Inhibition of NF-kappa B binding correlates with increased nuclear glucocorticoid receptor levels in acute alcohol-treated human monocytes.
Alcoholism, clinical and experimental research 2002;26(12):1872-9.
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2002: Szabo Gyongyi; Romics Laszlo; Frendl Gyorgy
Liver in sepsis and systemic inflammatory response syndrome.
Clinics in liver disease 2002;6(4):1045-66, x.
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2002: Mandrekar Pranoti; Dolganiuc Angela; Bellerose Gary; Kodys Karen; Romics Laszlo; Nizamani Rabia; Szabo Gyongyi
Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation?
Alcoholism, clinical and experimental research 2002;26(11):1609-14.
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2002: Drechsler Yvonne; Chavan Sangeeta; Catalano Donna; Mandrekar Pranoti; Szabo Gyongyi
FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development.
Journal of leukocyte biology 2002;72(4):657-67.
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2002: Bonkovsky Herbert L; Azar Riad; Bird Steven; Szabo Gyongyi; Banner Barbara
Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone.
Digestive diseases and sciences 2002;47(7):1632-7.
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2002: Szabo Gyongyi; Mandrekar Pranoti
Ethanol-mediated regulation of transcription factors in immunocompetent cells.
Frontiers in bioscience : a journal and virtual library 2002;7():a80-9.
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2001: Szabo G; Mandrekar P; Dolganiuc A; Catalano D; Kodys K
Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNgamma levels.
Alcoholism, clinical and experimental research 2001;25(12):1766-72.
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2001: Szabo G; Gavala C; Mandrekar P
Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(5):442-9.
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2001: Szabo G; Catalano D; Bellerose G; Mandrekar P
Interferon alpha and alcohol augment nuclear regulatory factor-kappaB activation in HepG2 cells, and interferon alpha increases pro-inflammatory cytokine production.
Alcoholism, clinical and experimental research 2001;25(8):1188-97.
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1999: Mandrekar P; Catalano D; Szabo G
Inhibition of lipopolysaccharide-mediated NFkappaB activation by ethanol in human monocytes.
International immunology 1999;11(11):1781-90.
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1999: Szabo G; Chavan S; Mandrekar P; Catalano D
Acute alcohol consumption attenuates interleukin-8 (IL-8) and monocyte chemoattractant peptide-1 (MCP-1) induction in response to ex vivo stimulation.
Journal of clinical immunology 1999;19(1):67-76.
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1998: Szabo G; Girouard L; Mandrekar P; Catalano D
Regulation of monocyte IL-12 production: augmentation by lymphocyte contact and acute ethanol treatment, inhibition by elevated intracellular cAMP.
International journal of immunopharmacology 1998;20(9):491-503.
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1998: Szabo G
Monocytes, alcohol use, and altered immunity.
Alcoholism, clinical and experimental research 1998;22(5 Suppl):216S-219S.
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1998: Girouard L; Mandrekar P; Catalano D; Szabo G
Regulation of monocyte interleukin-12 production by acute alcohol: a role for inhibition by interleukin-10.
Alcoholism, clinical and experimental research 1998;22(1):211-6.
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1997: Mandrekar P; Catalano D; Szabo G
Alcohol-induced regulation of nuclear regulatory factor-kappa beta in human monocytes.
Alcoholism, clinical and experimental research 1997;21(6):988-94.
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1996: Szabo G; Girouard L; Mandrekar P; Catalano D
Acute ethanol treatment augments interleukin-12 production in activated human monocytes.
Annals of the New York Academy of Sciences 1996;795():422-5.
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1996: Szabo G; Mandrekar P; Girouard L; Catalano D
Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production.
Alcoholism, clinical and experimental research 1996;20(5):900-7.
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1996: Mandrekar P; Catalano D; Girouard L; Szabo G
Human monocyte IL-10 production is increased by acute ethanol treatment.
Cytokine 1996;8(7):567-77.
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1995: Szabo G; Mandrekar P; Catalano D
Inhibition of superantigen-induced T cell proliferation and monocyte IL-1 beta, TNF-alpha, and IL-6 production by acute ethanol treatment.
Journal of leukocyte biology 1995;58(3):342-50.
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1994: Szabo G; Mandrekar P; Verma B; Isaac A; Catalano D
Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor alpha production late postinjury.
Journal of clinical immunology 1994;14(6):340-52.
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1994: Szabo G; Puppolo M; Verma B; Catalano D
Regulatory potential of ethanol and retinoic acid on human monocyte functions.
Alcoholism, clinical and experimental research 1994;18(3):548-54.
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1994: Szabo G; Kodys K; Miller-Graziano C L
Dibutyryl-cAMP modulation of receptor expression and antigen presentation capacity in monocyte subpopulations.
International journal of immunopharmacology 1994;16(2):151-62.
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1993: Szabo G; Verma B; Catalano D
Selective inhibition of antigen-specific T lymphocyte proliferation by acute ethanol exposure: the role of impaired monocyte antigen presentation capacity and mediator production.
Journal of leukocyte biology 1993;54(6):534-44.
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1993: Verma B K; Fogarasi M; Szabo G
Down-regulation of tumor necrosis factor alpha activity by acute ethanol treatment in human peripheral blood monocytes.
Journal of clinical immunology 1993;13(1):8-22.
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1992: Szabo G; Verma B K; Fogarasi M; Catalano D E
Induction of transforming growth factor-beta and prostaglandin E2 production by ethanol in human monocytes.
Journal of leukocyte biology 1992;52(6):602-10.
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1991: Szabo G; Kodys K; Miller-Graziano C L
Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of Fc gamma RI cross-linking stimulation.
Journal of clinical immunology 1991;11(6):326-35.
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1991: Szabo G; Kodys K; Miller-Graziano C L
Elevated monocyte interleukin-6 (IL-6) production in immunosppressed trauma patients. II. Downregulation by IL-4.
Journal of clinical immunology 1991;11(6):336-44.
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1991: Miller-Graziano C L; Szabo G; Griffey K; Mehta B; Kodys K; Catalano D
Role of elevated monocyte transforming growth factor beta (TGF beta) production in posttrauma immunosuppression.
Journal of clinical immunology 1991;11(2):95-102.
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1990: Miller-Graziano C L; Szabo G; Kodys K; Griffey K
Aberrations in post-trauma monocyte (MO) subpopulation: role in septic shock syndrome.
The Journal of trauma 1990;30(12 Suppl):S86-96.
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1990: Szabo G; Miller-Graziano C L
Induction and regulation of monocyte procoagulant activity.
Transplantation 1990;50(2):301-9.
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1990: Szabo G; Miller-Graziano C L; Wu J Y; Takayama T; Kodys K
Differential tumor necrosis factor production by human monocyte subsets.
Journal of leukocyte biology 1990;47(3):206-16.
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1990: Szabo G; Miller C L; Kodys K
Antigen presentation by the CD4 positive monocyte subset.
Journal of leukocyte biology 1990;47(2):111-20.
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1990: Takayama T K; Miller C; Szabo G
Elevated tumor necrosis factor alpha production concomitant to elevated prostaglandin E2 production by trauma patients' monocytes.
Archives of surgery (Chicago, Ill. : 1960) 1990;125(1):29-35.
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1988: Miller-Graziano C L; Fink M; Wu J Y; Szabo G; Kodys K
Mechanisms of altered monocyte prostaglandin E2 production in severely injured patients.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(3):293-9.
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