Benjamin Szwergold

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Robert A Maue; Robert W Burgess; Bing Wang; Christine M Wooley; Kevin L Seburn; Marie T Vanier; Maximillian A Rogers; Catherine C Chang; Ta-Yuan Chang; Brent T Harris; et al.
A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.
Benjamin S Szwergold; Richard D Bunker; Kerry M Loomes
The physiological substrates of fructosamine-3-kinase-related-protein (FN3KRP) are intermediates of nonenzymatic reactions between biological amines and ketose sugars (fructation products).
Matthew J Wargo; Benjamin S Szwergold; Deborah A Hogan
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.

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All Publications

2012: Robert A Maue; Robert W Burgess; Bing Wang; Christine M Wooley; Kevin L Seburn; Marie T Vanier; Maximillian A Rogers; Catherine C Chang; Ta-Yuan Chang; Brent T Harris; et al.
A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.
Human molecular genetics 2012;21(4):730-50.
2011: Benjamin S Szwergold; Richard D Bunker; Kerry M Loomes
The physiological substrates of fructosamine-3-kinase-related-protein (FN3KRP) are intermediates of nonenzymatic reactions between biological amines and ketose sugars (fructation products).
Medical hypotheses 2011;77(5):739-44.
2008: Matthew J Wargo; Benjamin S Szwergold; Deborah A Hogan
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Journal of bacteriology 2008;190(8):2690-9.
2007: Benjamin Szwergold; Yefim Manevich; Leo Payne; Kerry Loomes
Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme.
Biochemical and biophysical research communications 2007;361(4):870-5.
2007: Benjamin S Szwergold
Fructosamine-6-phosphates are deglycated by phosphorylation to fructosamine-3,6-bisphosphates catalyzed by fructosamine-3-kinase (FN3K) and/or fructosamine-3-kinase-related-protein (FN3KRP).
Medical hypotheses 2007;68(1):37-45.
2006: B S Szwergold
Alpha-thiolamines such as cysteine and cysteamine act as effective transglycating agents due to formation of irreversible thiazolidine derivatives.
Medical hypotheses 2006;66(4):698-707.
2005: Gerard T Berry; John W Baynes; Kevin J Wells-Knecht; Benjamin S Szwergold; René Santer
Elements of diabetic nephropathy in a patient with GLUT 2 deficiency.
Molecular genetics and metabolism 2005;86(4):473-7.
2005: Paul J Beisswenger; Keith S Drummond; Robert G Nelson; Scott K Howell; Benjamin S Szwergold; Michael Mauer
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
Diabetes 2005;54(11):3274-81.
2005: Benjamin S Szwergold
Carnosine and anserine act as effective transglycating agents in decomposition of aldose-derived Schiff bases.
Biochemical and biophysical research communications 2005;336(1):36-41.
2005: Benjamin S Szwergold; Scott K Howell; Paul J Beisswenger
Transglycation--a potential new mechanism for deglycation of Schiff's bases.
Annals of the New York Academy of Sciences 2005;1043():845-64.
2005: James R Conner; Paul J Beisswenger; Benjamin S Szwergold
Some clues as to the regulation, expression, function, and distribution of fructosamine-3-kinase and fructosamine-3-kinase-related protein.
Annals of the New York Academy of Sciences 2005;1043():824-36.
2005: Benjamin S Szwergold; Sundeep Lal
Identification of diadenosine-triphosphate in mature bovine lenses.
Biochemical and biophysical research communications 2005;326(4):718-23.
2005: Benjamin S Szwergold
Intrinsic toxicity of glucose, due to non-enzymatic glycation, is controlled in-vivo by deglycation systems including: FN3K-mediated deglycation of fructosamines and transglycation of aldosamines.
Medical hypotheses 2005;65(2):337-48.
2004: James R Conner; Paul J Beisswenger; Benjamin S Szwergold
The expression of the genes for fructosamine-3-kinase and fructosamine-3-kinase-related protein appears to be constitutive and unaffected by environmental signals.
Biochemical and biophysical research communications 2004;323(3):932-6.
2003: B S Szwergold; P J Beisswenger
Enzymatic deglycation--a new paradigm or an epiphenomenon?
Biochemical Society transactions 2003;31(Pt 6):1428-32.
2003: P J Beisswenger; S K Howell; R G Nelson; M Mauer; B S Szwergold
Alpha-oxoaldehyde metabolism and diabetic complications.
Biochemical Society transactions 2003;31(Pt 6):1358-63.
2003: Paul J Beisswenger; Scott K Howell; Kenneth Smith; Benjamin S Szwergold
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes.
Biochimica et biophysica acta 2003;1637(1):98-106.
2001: B S Szwergold; S Howell; P J Beisswenger
Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo.
Diabetes 2001;50(9):2139-47.
2001: P J Beisswenger; S K Howell; R M O'Dell; M E Wood; A D Touchette; B S Szwergold
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia.
Diabetes care 2001;24(4):726-32.
2001: P J Beisswenger; B S Szwergold; K T Yeo
Glycated proteins in diabetes.
Clinics in laboratory medicine 2001;21(1):53-78, vi.
1999: P J Beisswenger; S K Howell; A D Touchette; S Lal; B S Szwergold
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Diabetes 1999;48(1):198-202.
1997: S Lal; W C Randall; A H Taylor; F Kappler; M Walker; T R Brown; B S Szwergold
Fructose-3-phosphate production and polyol pathway metabolism in diabetic rat hearts.
Metabolism: clinical and experimental 1997;46(11):1333-8.
1997: J C Street; B S Szwergold; C Matei; F Kappler; U Mahmood; T R Brown; J A Koutcher
Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(5):769-75.
1997: S Lal; F Kappler; M Walker; T J Orchard; P J Beisswenger; B S Szwergold; T R Brown
Quantitation of 3-deoxyglucosone levels in human plasma.
Archives of biochemistry and biophysics 1997;342(2):254-60.
1996: A C Kuesel; R Stoyanova; N R Aiken; C W Li; B S Szwergold; C Shaller; T R Brown
Quantitation of resonances in biological 31P NMR spectra via principal component analysis: potential and limitations.
NMR in biomedicine 1996;9(3):93-104.
1995: F Kappler; B Su; B S Szwergold; W C Randall; T R Brown
Identification of galactitol 2-phosphate and galactitol 3-phosphate in the lens of galactose-fed rats.
Metabolism: clinical and experimental 1995;44(12):1527-31.
1995: B S Szwergold; S Lal; A H Taylor; F Kappler; B Su; T R Brown
31P-nuclear magnetic resonance evidence of an activated hexose-monophosphate shunt in hyperglycemic rat lenses in vivo.
Diabetes 1995;44(7):810-5.
1995: S Lal; B S Szwergold; A H Taylor; W C Randall; F Kappler; K Wells-Knecht; J W Baynes; T R Brown
Metabolism of fructose-3-phosphate in the diabetic rat lens.
Archives of biochemistry and biophysics 1995;318(1):191-9.
1995: S Lal; B S Szwergold; A H Taylor; W C Randall; F Kappler; T R Brown
Production of fructose and fructose-3-phosphate in maturing rat lenses.
Investigative ophthalmology & visual science 1995;36(5):969-73.
1995: B S Szwergold; K Ugurbil; T R Brown
Properties of fructose-1,6-bisphosphate aldolase from Escherichia coli: an NMR analysis.
Archives of biochemistry and biophysics 1995;317(1):244-52.
1994: B S Szwergold; F Kappler; M Moldes; C Shaller; T R Brown
Characterization of a phosphonium analog of choline as a probe in 31P NMR studies of phospholipid metabolism.
NMR in biomedicine 1994;7(3):121-7.
1994: S Lal; B S Szwergold; F Kappler; T Brown
Effect of pH on the bioenergetics of perfused porcine lenses.
Current eye research 1994;13(3):239-42.
1993: B Su; F Kappler; B S Szwergold; T R Brown
Identification of a putative tumor marker in breast and colon cancer.
Cancer research 1993;53(8):1751-4.
1993: S Lal; B S Szwergold; F Kappler; T Brown
Detection of fructose-3-phosphokinase activity in intact mammalian lenses by 31P NMR spectroscopy.
The Journal of biological chemistry 1993;268(11):7763-7.
1992: C W Marano; B S Szwergold; F Kappler; T R Brown; F M Matschinsky
Human retinal pigment epithelial cells cultured in hyperglycemic media accumulate increased amounts of glycosaminoglycan precursors.
Investigative ophthalmology & visual science 1992;33(9):2619-25.
1992: D B Rolin; P E Pfeffer; S F Osman; B S Szwergold; F Kappler; A J Benesi
Structural studies of a phosphocholine substituted beta-(1,3);(1,6) macrocyclic glucan from Bradyrhizobium japonicum USDA 110.
Biochimica et biophysica acta 1992;1116(3):215-25.
1992: A Petersen; F Kappler; B S Szwergold; T R Brown
Fructose metabolism in the human erythrocyte. Phosphorylation to fructose 3-phosphate.
The Biochemical journal 1992;284 ( Pt 2)():363-6.
1992: B S Szwergold
NMR spectroscopy of cells.
Annual review of physiology 1992;54():775-98.
1990: B S Szwergold; F Kappler; L H Cohen; D Nanavati; T R Brown
Identification of a naturally occurring methyl-ester of phosphate, methyl-phosphorylcholine (methyl-2-(N,N,N trimethylamino) ethyl phosphate), in the eggs of the sea urchin S. purpuratus.
Biochemical and biophysical research communications 1990;172(2):855-61.
1990: A Petersen; B S Szwergold; F Kappler; M Weingarten; T R Brown
Identification of sorbitol 3-phosphate and fructose 3-phosphate in normal and diabetic human erythrocytes.
The Journal of biological chemistry 1990;265(29):17424-7.
1990: B S Szwergold; F Kappler; T R Brown
Identification of fructose 3-phosphate in the lens of diabetic rats.
Science (New York, N.Y.) 1990;247(4941):451-4.
1989: B S Szwergold; F Kappler; T R Brown; P Pfeffer; S F Osman
Identification of D-sorbitol 3-phosphate in the normal and diabetic mammalian lens.
The Journal of biological chemistry 1989;264(16):9278-82.
1989: B S Szwergold; T R Brown; J J Freed
Bicarbonate abolishes intracellular alkalinization in mitogen-stimulated 3T3 cells.
Journal of cellular physiology 1989;138(2):227-35.
1988: B S Szwergold; T R Brown; J J Freed
Bicarbonate abolishes intracellular alkalinization in mitogen-stimulated NIH 3T3 cells.
Annals of the New York Academy of Sciences 1988;551():277-9.
1987: B S Szwergold; R A Graham; T R Brown
Observation of inositol pentakis- and hexakis-phosphates in mammalian tissues by 31P NMR.
Biochemical and biophysical research communications 1987;149(3):874-81.
1987: R A Graham; R A Meyer; B S Szwergold; T R Brown
Observation of myo-inositol 1,2-(cyclic) phosphate in a Morris hepatoma by 31P NMR.
The Journal of biological chemistry 1987;262(1):35-7.
1987: T R Brown; R A Graham; B S Szwergold; W J Thoma; R A Meyer
Phosphorylated metabolites in tumors, tissues, and cell lines.
Annals of the New York Academy of Sciences 1987;508():229-40.