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Guillermo Taccioli

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Tammy Morrish; José L Garcia-Perez; Thomas D Stamato; Guillermo E Taccioli; JoAnn Sekiguchi; John V Moran
Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres.
Marta Martín; Anna Genescà; Laura Latre; Isabel Jaco; Guillermo E Taccioli; Josep Egozcue; María A Blasco; George Iliakis; Laura Tusell
Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
Silvia Espejel; Peter Klatt; Josiane Ménissier-de Murcia; Juan Martín-Caballero; Juana M Flores; Guillermo E Taccioli; Gilbert de Murcia; María A Blasco
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.

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All Publications

2007: Tammy Morrish; José L Garcia-Perez; Thomas D Stamato; Guillermo E Taccioli; JoAnn Sekiguchi; John V Moran
Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres.
Nature 2007;446(7132):208-12.
2005: Marta Martín; Anna Genescà; Laura Latre; Isabel Jaco; Guillermo E Taccioli; Josep Egozcue; María A Blasco; George Iliakis; Laura Tusell
Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
Cancer research 2005;65(22):10223-32.
2004: Silvia Espejel; Peter Klatt; Josiane Ménissier-de Murcia; Juan Martín-Caballero; Juana M Flores; Guillermo E Taccioli; Gilbert de Murcia; María A Blasco
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs.
The Journal of cell biology 2004;167(4):627-38.
2003: Isabel Jaco; Purificación Muñoz; Fermín A Goytisolo; Joanna Wesoly; Susan Bailey; Guillermo E Taccioli; María A Blasco
Role of mammalian Rad54 in telomere length maintenance.
Molecular and cellular biology 2003;23(16):5572-80.
2003: Héctor A Lucero; Darren Gae; Guillermo E Taccioli
Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response.
The Journal of biological chemistry 2003;278(24):22136-43.
2002: Silvia Espejel; Sonia Franco; Antonella Sgura; Darren Gae; Susan M Bailey; Guillermo E Taccioli; María A Blasco
Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.
The EMBO journal 2002;21(22):6275-87.
2002: Tammy Morrish; Nicolas Gilbert; Jeremy S Myers; Bethaney J Vincent; Thomas D Stamato; Guillermo E Taccioli; Mark A Batzer; John V Moran
DNA repair mediated by endonuclease-independent LINE-1 retrotransposition.
Nature genetics 2002;31(2):159-65.
2001: Fredrik Bryntesson; J C Regan; Penny A Jeggo; Guillermo E Taccioli; Mike Hubank
Analysis of gene transcription in cells lacking DNA-PK activity.
Radiation research 2001;156(2):167-76.
2001: Chiara Mondello; Paola Rebuzzini; M Dolzan; S Edmonson; Guillermo E Taccioli; Elena Giulotto
Increased gene amplification in immortal rodent cells deficient for the DNA-dependent protein kinase catalytic subunit.
Cancer research 2001;61(11):4520-5.
2001: Fermín A Goytisolo; Enrique Samper; S Edmonson; Guillermo E Taccioli; María A Blasco
The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.
Molecular and cellular biology 2001;21(11):3642-51.
2000: Sanjeev Shangary; Kevin D Brown; Aaron W Adamson; S Edmonson; Bobby Ng; Tej K Pandita; Jack C Yalowich; Guillermo E Taccioli; Rajasekaran Baskaran
Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process.
The Journal of biological chemistry 2000;275(39):30163-8.
1999: GS Jimenez; Fredrik Bryntesson; MI Torres Arzayus; A Priestley; Michelle Beeche; S Saito; K Sakaguchi; E Appella; Penny A Jeggo; Guillermo E Taccioli; Geoffrey M Wahl; Mike Hubank
DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage.
Nature 1999;400(6739):81-3.
1999: BK Singleton; MI Torres Arzayus; S T Rottinghaus; Guillermo E Taccioli; Penny A Jeggo
The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit.
Molecular and cellular biology 1999;19(5):3267-77.
1998: Guillermo E Taccioli; A G Amatucci; Heather Beamish; D Gell; XH Xiang; MI Torres Arzayus; A Priestley; Stephen P Jackson; Ann Marshak-Rothstein; Penny A Jeggo; Victoria L M Herrera
Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity.
Immunity 1998;9(3):355-66.
1998: A Priestley; Heather Beamish; D Gell; A G Amatucci; M C Muhlmann-Diaz; BK Singleton; G C Smith; T Blunt; L C Schalkwyk; Joel S Bedford; Stephen P Jackson; Penny A Jeggo; Guillermo E Taccioli
Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20.
Nucleic acids research 1998;26(8):1965-73.
1997: J Y Lin; M C Mühlmann-Diaz; M A Stackhouse; JF Robinson; Guillermo E Taccioli; D J Chen; Joel S Bedford
An ionizing radiation-sensitive CHO mutant cell line: irs-20. IV. Genetic complementation, V(D)J recombination and the scid phenotype.
Radiation research 1997;147(2):166-71.
1996: T Blunt; D Gell; M Fox; Guillermo E Taccioli; Alan Lehmann; Stephen P Jackson; Penny A Jeggo
Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10285-90.
1996: R Mizuta; Guillermo E Taccioli; F W Alt
The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene.
International immunology 1996;8(9):1467-71.
1996: Penny A Jeggo; Stephen P Jackson; Guillermo E Taccioli
Identification of the catalytic subunit of DNA dependent protein kinase as the product of the mouse scid gene.
Current topics in microbiology and immunology 1996;217():79-89.
1995: Z Li; T Otevrel; Yijie Gao; Hwei-Ling Cheng; B Seed; Thomas D Stamato; Guillermo E Taccioli; F W Alt
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination.
Cell 1995;83(7):1079-89.
1995: T Blunt; Guillermo E Taccioli; A Priestley; M Hafezparast; T McMillan; J Liu; C C Cole; J White; F W Alt; Stephen P Jackson
A YAC contig encompassing the XRCC5 (Ku80) DNA repair gene and complementation of defective cells by YAC protoplast fusion.
Genomics 1995;30(2):320-8.
1995: Penny A Jeggo; Guillermo E Taccioli; Stephen P Jackson
Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(11):949-57.
1995: Guillermo E Taccioli; F W Alt
Potential targets for autosomal SCID mutations.
Current opinion in immunology 1995;7(4):436-40.
1995: T Blunt; N J Finnie; Guillermo E Taccioli; G C Smith; Jocelyne Demengeot; Tanya Gottlieb; R Mizuta; A J Varghese; F W Alt; Penny A Jeggo; S P Jackson
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.
Cell 1995;80(5):813-23.
1994: Guillermo E Taccioli; Tanya Gottlieb; T Blunt; A Priestley; Jocelyne Demengeot; R Mizuta; Alan Lehmann; F W Alt; Stephen P Jackson; Penny A Jeggo
Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination.
Science (New York, N.Y.) 1994;265(5177):1442-5.
1994: Guillermo E Taccioli; Hwei-Ling Cheng; A J Varghese; G Whitmore; F W Alt
A DNA repair defect in Chinese hamster ovary cells affects V(D)J recombination similarly to the murine scid mutation.
The Journal of biological chemistry 1994;269(10):7439-42.
1993: E M Oltz; F W Alt; W C Lin; J Chen; Guillermo E Taccioli; Stephen Desiderio; GA Rathbun
A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination.
Molecular and cellular biology 1993;13(10):6223-30.
1993: Guillermo E Taccioli; GA Rathbun; E Oltz; Thomas D Stamato; Penny A Jeggo; F W Alt
Impairment of V(D)J recombination in double-strand break repair mutants.
Science (New York, N.Y.) 1993;260(5105):207-10.
1992: F W Alt; E M Oltz; F Young; J Gorman; Guillermo E Taccioli; J Chen
VDJ recombination.
Immunology today 1992;13(8):306-14.
1992: F W Alt; GA Rathbun; E Oltz; Guillermo E Taccioli; Y Shinkai
Function and control of recombination-activating gene activity.
Annals of the New York Academy of Sciences 1992;651():277-94.
1992: Guillermo E Taccioli; GA Rathbun; Y Shinkai; E M Oltz; H Cheng; G Whitmore; Thomas D Stamato; Penny A Jeggo; F W Alt
Activities involved in V(D)J recombination.
Current topics in microbiology and immunology 1992;182():107-14.