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Seifu Tadesse

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Chemicals & Drugs

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Chemistry, Organic

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Publications

TOP 3
Raju Subramanian; Matthew R Lee; John G Allen; Matthew P Bourbeau; Christopher Fotsch; Fang-Tsao Hong; Seifu Tadesse; Guomin Yao; Chester C Yuan; Sekhar Surapaneni; Gary L Skiles; Xianghong Wang; G Erich Wohlhieter; Qingping Zeng; Yihong Zhou; Xiaochun Zhu; Chun Li
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screening.
Qingping Zeng; John G Allen; Matthew P Bourbeau; Xianghong Wang; Guomin Yao; Seifu Tadesse; James T Rider; Chester C Yuan; Fang-Tsao Hong; Matthew R Lee; Shiwen Zhang; Julie A Lofgren; Daniel J Freeman; Suijin Yang; Chun Li; Elizabeth Tominey; Xin Huang; Douglas Hoffman; Harvey K Yamane; Christopher Fotsch; Celia Dominguez; Randall W Hungate; Xiaoling Zhang
Azole-based inhibitors of AKT/PKB for the treatment of cancer.
Tasir S Haque; Seifu Tadesse; Jovita Marcinkeviciene; Martin Rogers; Christine F Sizemore; Lisa M Kopcho; Karen M Amsler; Lisa D Ecret; Dong Liang Zhan; Frank Hobbs; Andrew Slee; George L Trainor; Andrew M Stern; Robert Copeland; Andrew P Combs
Parallel synthesis of potent, pyrazole-based inhibitors of Helicobacter pylori dihydroorotate dehydrogenase.

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All Publications

2010: Raju Subramanian; Matthew R Lee; John G Allen; Matthew P Bourbeau; Christopher Fotsch; Fang-Tsao Hong; Seifu Tadesse; Guomin Yao; Chester C Yuan; Sekhar Surapaneni; Gary L Skiles; Xianghong Wang; G Erich Wohlhieter; Qingping Zeng; Yihong Zhou; Xiaochun Zhu; Chun Li
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screening.
Chemical research in toxicology 2010;23(3):653-63.
2010: Qingping Zeng; John G Allen; Matthew P Bourbeau; Xianghong Wang; Guomin Yao; Seifu Tadesse; James T Rider; Chester C Yuan; Fang-Tsao Hong; Matthew R Lee; Shiwen Zhang; Julie A Lofgren; Daniel J Freeman; Suijin Yang; Chun Li; Elizabeth Tominey; Xin Huang; Douglas Hoffman; Harvey K Yamane; Christopher Fotsch; Celia Dominguez; Randall W Hungate; Xiaoling Zhang
Azole-based inhibitors of AKT/PKB for the treatment of cancer.
Bioorganic & medicinal chemistry letters 2010;20(5):1559-64.
2002: Tasir S Haque; Seifu Tadesse; Jovita Marcinkeviciene; Martin Rogers; Christine F Sizemore; Lisa M Kopcho; Karen M Amsler; Lisa D Ecret; Dong Liang Zhan; Frank Hobbs; Andrew Slee; George L Trainor; Andrew M Stern; Robert Copeland; Andrew P Combs
Parallel synthesis of potent, pyrazole-based inhibitors of Helicobacter pylori dihydroorotate dehydrogenase.
Journal of medicinal chemistry 2002;45(21):4669-78.
2002: Andrew P Combs; Seifu Tadesse; Maria Rafalski; Tasir S Haque; Patrick Y S Lam
N-arylation of primary and secondary aliphatic amines on solid supports.
Journal of combinatorial chemistry 2002;4(2):179-82.
2000: Robert Copeland; Jovita Marcinkeviciene; Tasir S Haque; Lisa M Kopcho; Wenjun Jiang; K Wang; L D Ecret; Christine F Sizemore; K A Amsler; L Foster; Seifu Tadesse; Andrew P Combs; Andrew M Stern; George L Trainor; Andrew Slee; Martin Rogers; Frank Hobbs
Helicobacter pylori-selective antibacterials based on inhibition of pyrimidine biosynthesis.
The Journal of biological chemistry 2000;275(43):33373-8.