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Andrew Tager

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TOP 3
Norihiko Sakai; Andrew M Tager
Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis.
Norihiko Sakai; Jerold Chun; Jeremy S Duffield; Andrew D Luster; Takashi Wada; Andrew M Tager
LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.
Chen Sabrina Tan; Raphael Viscidi; Vlad Vrbanac; Thomas A Broge; Jennifer Gordon; Edward Seung; Andrew M Tager; Igor J Koralnik
Detection of JC Virus-Specific Immune Responses in a Novel Humanized Mouse Model.

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All Publications

2013: Norihiko Sakai; Andrew M Tager
Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis.
Biochimica et biophysica acta 2013;1832(7):911-21.
2013: Norihiko Sakai; Jerold Chun; Jeremy S Duffield; Andrew D Luster; Takashi Wada; Andrew M Tager
LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(5):1830-46.
2013: Chen Sabrina Tan; Raphael Viscidi; Vlad Vrbanac; Thomas A Broge; Jennifer Gordon; Edward Seung; Andrew M Tager; Igor J Koralnik
Detection of JC Virus-Specific Immune Responses in a Novel Humanized Mouse Model.
PloS one 2013;8(5):e64313.
2013: Daniel J Tschumperlin; Fei Liu; Andrew M Tager
Biomechanical regulation of mesenchymal cell function.
Current opinion in rheumatology 2013;25(1):92-100.
2012: Thomas T Murooka; Edward Seung; Andrew M Tager; Ulrich H von Andrian; Vladimir D Vrbanac; Maud Deruaz; Andrew D Luster; Francesco Marangoni; Thorsten R Mempel
HIV-infected T cells are migratory vehicles for viral dissemination.
Nature 2012;490(7419):283-7.
2012: Timothy E Dudek; Lena Fadda; Xiaojiang Gao; Adrianne D Gladden; Andrew D Luster; Elizabeth F Mellors; Daniel C No; Karen A Power; Edward Seung; Andrew M Tager; Trevor R Tivey; Vladimir D Vrbanac; Marcus Altfeld; Laura Battis; Priyasma Bhoumik; Christian L Boutwell; Todd M Allen
Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice.
Science translational medicine 2012;4(143):143ra98.
2012: Barry S Shea; Andrew M Tager
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.
Proceedings of the American Thoracic Society 2012;9(3):102-10.
2012: David Lagares; Santiago Lamas; Andrew Leask; Shangxi Liu; David Abraham; Oscar Busnadiego; Patricia Carreira; David E Carter; Benjamin A Fontaine; Rosa Ana García-Fernández; Mohit Kapoor; Barry S Shea; Xu Shi-wen; Andrew M Tager; Fernando Rodríguez-Pascual
Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation.
Arthritis and rheumatism 2012;64(5):1653-64.
2012: Manuela Funke; Yan Xu; Zhenwen Zhao; Jerold Chun; Andrew M Tager
The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury.
American journal of respiratory cell and molecular biology 2012;46(3):355-64.
2012: Matthew B Greenblatt; Andrew M Tager; Trevor Tivey; Kelly Tsang; Vladimir Vbranac; Antonios O Aliprantis
Graft versus host disease in the bone marrow, liver and thymus humanized mouse model.
PloS one 2012;7(9):e44664.
2012: Barry S Shea; Andrew M Tager
Sphingolipid regulation of tissue fibrosis.
The open rheumatology journal 2012;6():123-9.
2010: Barry S Shea; Sarah F Brooks; Benjamin A Fontaine; Jerold Chun; Andrew D Luster; Andrew M Tager
Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.
American journal of respiratory cell and molecular biology 2010;43(6):662-73.
2010: Fei Liu; Justin D Mih; Barry S Shea; Alvin T Kho; Asma S Sharif; Andrew M Tager; Daniel J Tschumperlin
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.
The Journal of cell biology 2010;190(4):693-706.
2009: Diana M Brainard; Edward Seung; Nicole Frahm; Annaiah Cariappa; Charles C Bailey; William K Hart; Hae-Sook Shin; Sarah F Brooks; Heather L Knight; Quentin Eichbaum; Yong-Guang Yang; Megan Sykes; Bruce D Walker; Gordon J Freeman; Shiv Pillai; Susan V Westmoreland; Christian Brander; Andrew D Luster; Andrew M Tager
Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.
Journal of virology 2009;83(14):7305-21.
2009: Zamaneh Mikhak; Mieko Fukui; Alireza Farsidjani; Benjamin D Medoff; Andrew M Tager; Andrew D Luster
Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.
The Journal of allergy and clinical immunology 2009;123(1):67-73.e3.
2008: Gabriele S V Campanella; Andrew M Tager; Joseph K El Khoury; Seddon Y Thomas; Tabitha A Abrazinski; Lindsay A Manice; Richard A Colvin; Andrew D Luster
Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4814-9.
2008: Andrew M Tager; Peter LaCamera; Barry S Shea; Gabriele S V Campanella; Moisés Selman; Zhenwen Zhao; Vasiliy V Polosukhin; John Wain; Banu A Karimi-Shah; Nancy D Kim; William K Hart; Annie Pardo; Timothy S Blackwell; Yan Xu; Jerold Chun; Andrew D Luster
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.
Nature medicine 2008;14(1):45-54.
2007: Diana M Brainard; Andrew M Tager; Joseph Misdraji; Nicole Frahm; Mathias Lichterfeld; Rika Draenert; Christian Brander; Bruce D Walker; Andrew D Luster
Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction.
Journal of virology 2007;81(16):8439-50.
2007: Neil Ahluwalia; Alexander Y Lin; Andrew M Tager; Ivy E Pruitt; Thomas J T Anderson; Fjoralba Kristo; Dongxiao Shen; Anna R Cruz; Masanori Aikawa; Andrew D Luster; Robert E Gerszten
Inhibited aortic aneurysm formation in BLT1-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):691-7.
2006: Eric A Heller; Emerson Liu; Andrew M Tager; Qian Yuan; Alexander Y Lin; Neil Ahluwalia; Krister Jones; Stephanie L Koehn; Vincent M Lok; Elena Aikawa; Kathryn J Moore; Andrew D Luster; Robert E Gerszten
Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells.
Circulation 2006;113(19):2301-12.
2006: Nancy D Kim; Richard C Chou; Edward Seung; Andrew M Tager; Andrew D Luster
A unique requirement for the leukotriene B4 receptor BLT1 for neutrophil recruitment in inflammatory arthritis.
The Journal of experimental medicine 2006;203(4):829-35.
2006: Zamaneh Mikhak; Carolyn M Fleming; Benjamin D Medoff; Seddon Y Thomas; Andrew M Tager; Gabriele S V Campanella; Andrew D Luster
STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4959-67.
2006: Sabina A Islam; Seddon Y Thomas; Christoph Hess; Benjamin D Medoff; Terry K Means; Christian Brander; Craig M Lilly; Andrew M Tager; Andrew D Luster
The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans.
Blood 2006;107(2):444-53.
2006: Benjamin D Medoff; Andrew M Tager; Ryan Jackobek; Terry K Means; Lan Wang; Andrew D Luster
Antibody-antigen interaction in the airway drives early granulocyte recruitment through BLT1.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L170-8.
2005: Eric A Heller; Emerson Liu; Andrew M Tager; Sumita Sinha; Jesse D Roberts; Stephanie L Koehn; Peter Libby; Elena Aikawa; Ji Qiu Chen; Paul Huang; Mason W Freeman; Kathryn J Moore; Andrew D Luster; Robert E Gerszten
Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.
Circulation 2005;112(4):578-86.
2005: Benjamin D Medoff; Edward Seung; John C Wain; Terry K Means; Gabriele S V Campanella; Sabina A Islam; Seddon Y Thomas; Leo C Ginns; Nir Grabie; Andrew H Lichtman; Andrew M Tager; Andrew D Luster
BLT1-mediated T cell trafficking is critical for rejection and obliterative bronchiolitis after lung transplantation.
The Journal of experimental medicine 2005;202(1):97-110.
2004: Andrew M Tager; Richard L Kradin; Peter LaCamera; Scott D Bercury; Gabriele S V Campanella; Carol P Leary; Vasiliy V Polosukhin; Long-Hai Zhao; Hideo Sakamoto; Timothy S Blackwell; Andrew D Luster
Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10.
American journal of respiratory cell and molecular biology 2004;31(4):395-404.
2004: Andrew D Luster; Andrew M Tager
T-cell trafficking in asthma: lipid mediators grease the way.
Nature reviews. Immunology 2004;4(9):711-24.
2003: Katayoon Goodarzi; Mahmoud Goodarzi; Andrew M Tager; Andrew D Luster; Ulrich H von Andrian
Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues.
Nature immunology 2003;4(10):965-73.
2003: Andrew M Tager; Shannon K Bromley; Benjamin D Medoff; Sabina A Islam; Scott D Bercury; Erik B Friedrich; Andrew D Carafone; Robert E Gerszten; Andrew D Luster
Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment.
Nature immunology 2003;4(10):982-90.
2003: Erik B Friedrich; Andrew M Tager; Emerson Liu; Annika Pettersson; Christer Owman; Lance L Munn; Andrew D Luster; Robert E Gerszten
Mechanisms of leukotriene B4--triggered monocyte adhesion.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(10):1761-7.
2003: Andrew M Tager; Andrew D Luster
BLT1 and BLT2: the leukotriene B(4) receptors.
Prostaglandins, leukotrienes, and essential fatty acids 2003;69(2-3):123-34.
2002: Benjamin D Medoff; Alain Sauty; Andrew M Tager; James A Maclean; Rex Smith; Anuja Mathew; Jennifer H Dufour; Andrew D Luster
IFN-gamma-inducible protein 10 (CXCL10) contributes to airway hyperreactivity and airway inflammation in a mouse model of asthma.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5278-86.
2001: Anuja Mathew; James A Maclean; Elliot N. DeHaan; Andrew M Tager; Francis H Y Green; Andrew D Luster
Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation.
The Journal of experimental medicine 2001;193(9):1087-96.
2001: Fumito Ichinose; Warren M Zapol; Adam Sapirstein; Roman Ullrich; Andrew M Tager; K Coggins; R Jones; Kenneth D Bloch
Attenuation of hypoxic pulmonary vasoconstriction by endotoxemia requires 5-lipoxygenase in mice.
Circulation research 2001;88(8):832-8.
2000: Andrew M Tager; Jennifer H Dufour; Katayoon Goodarzi; Scott D Bercury; Ulrich H von Andrian; Andrew D Luster
BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis.
The Journal of experimental medicine 2000;192(3):439-46.
1999: Andrew M Tager; Andrew D Luster; Carol P Leary; Hideo Sakamoto; Long-Hai Zhao; Frederic Preffer; Richard L Kradin
Accessory cells with immunophenotypic and functional features of monocyte-derived dendritic cells are recruited to the lung during pulmonary inflammation.
Journal of leukocyte biology 1999;66(6):901-8.
1999: Andrew M Tager; Andrew D Luster; Richard L Kradin
T-cell chemokines interferon-inducible protein-10 and monokine induced by interferon-gamma are upregulated in bleomycin-induced lung injury.
Chest 1999;116(1 Suppl):90S.
1999: D Quinn; Andrew M Tager; P M Joseph; J V Bonventre; T Force; Charles A Hales
Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells.
Chest 1999;116(1 Suppl):89S-90S.
1998: Andrew M Tager; J Wu; MW Vermeulen
The effect of chloride concentration on human neutrophil functions: potential relevance to cystic fibrosis.
American journal of respiratory cell and molecular biology 1998;19(4):643-52.
1996: Andrew M Tager; Leo C Ginns
Complications of lung transplantation.
Critical care nursing clinics of North America 1996;8(3):273-92.