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Orazio Taglialatela-Scafati

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Orazio Taglialatela-Scafati; Warunya Arunotayanun; Mauro Ballero; Giuseppina Chianese; Simon Gibbons; Blessing Mabebie; Alberto Minassi; Federica Pollastro; Giovanni Appendino
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
Valentina Sepe; Orazio Taglialatela-Scafati; Raffaella Ummarino; Giuseppe Bifulco; Maria Giovanna Chini; Claudio D'Amore; Maria Valeria D'auria; Stefano Fiorucci; Nobuhiro Fusetani; Simona De Marino; Yoichi Nakao; Barbara Renga; Angela Zampella
Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
Giuseppina Chianese; Ernesto Fattorusso; Vincenzo Di Marzo; Aniello Schiano Moriello; Luciano De Petrocellis; Masteria Yunovilsa Putra; Giorgio Bavestrello; Barbara Calcinai; Orazio Taglialatela-Scafati
Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels.

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All Publications

2013: Orazio Taglialatela-Scafati; Warunya Arunotayanun; Mauro Ballero; Giuseppina Chianese; Simon Gibbons; Blessing Mabebie; Alberto Minassi; Federica Pollastro; Giovanni Appendino
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
Journal of natural products 2013;76(3):346-53.
2012: Valentina Sepe; Orazio Taglialatela-Scafati; Raffaella Ummarino; Giuseppe Bifulco; Maria Giovanna Chini; Claudio D'Amore; Maria Valeria D'auria; Stefano Fiorucci; Nobuhiro Fusetani; Simona De Marino; Yoichi Nakao; Barbara Renga; Angela Zampella
Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
Marine drugs 2012;10(11):2448-66.
2012: Giuseppina Chianese; Ernesto Fattorusso; Vincenzo Di Marzo; Aniello Schiano Moriello; Luciano De Petrocellis; Masteria Yunovilsa Putra; Giorgio Bavestrello; Barbara Calcinai; Orazio Taglialatela-Scafati
Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels.
Marine drugs 2012;10(11):2435-47.
2012: Giuseppina Chianese; Henny A Dien; Ernesto Fattorusso; Marcel Kaiser; Fernando Scala; Giorgio Bavestrello; Barbara Calcinai; Deniz Tasdemir; Roberta Teta; Orazio Taglialatela-Scafati
Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin.
Organic & biomolecular chemistry 2012;10(35):7197-207.
2012: Masteria Yunovilsa Putra; Giorgio Bavestrello; Carlo Cerrano; Ernesto Fattorusso; ANGELA IANARO; Elisabetta Panza; Orazio Taglialatela-Scafati
Sinularioside, a triacetylated glycolipid from the Indonesian soft coral Sinularia sp., is an inhibitor of NO release.
Bioorganic & medicinal chemistry letters 2012;22(8):2723-5.
2012: Masteria Yunovilsa Putra; Barbara Renga; Giorgio Bavestrello; Carlo Cerrano; Claudio D'Amore; Ernesto Fattorusso; Stefano Fiorucci; Orazio Taglialatela-Scafati
Polyhydroxylated sterols from the Indonesian soft coral Sinularia sp. and their effect on farnesoid X-activated receptor.
Steroids 2012;77(5):433-40.
2012: Orazio Taglialatela-Scafati; Zuhal Toker; Hasan Çetin Özen; Maria Luz Bellido; Giuseppina Chianese; Lavinia Cicione; Eduardo Munoz; Federica Pollastro; Giovanni Appendino
STAT-3 inhibitory bisabolanes from Carthamus glaucus.
Journal of natural products 2012;75(3):453-8.
2012: Romina Nassini; Bernd Nilius; Frank Porreca; Jean Prenen; Delia Preti; Laura Sadofsky; Orazio Taglialatela-Scafati; Joris Vriens; Eunice Andrè; Giovanni Appendino; Cristina Avonto; Silvia Benemei; Luciano De Petrocellis; Gaetano De Siena; Vincenzo Di Marzo; Greg Dussor; Giancarlo la Marca; Serena Materazzi; Pierangelo Geppetti
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.
Brain : a journal of neurology 2012;135(Pt 2):376-90.
2011: Rihab F Angawi; Giorgio Bavestrello; Barbara Calcinai; Giuseppina Chianese; Henny Adeleida Dien; Giovanna Donnarumma; Ernesto Fattorusso; Elena Grimaldi; Iole Paoletti; Maria Antonietta Tufano; Orazio Taglialatela-Scafati
Aurantoside J: a new tetramic acid glycoside from Theonella swinhoei. Insights into the antifungal potential of aurantosides.
Marine drugs 2011;9(12):2809-17.
2011: Jian Zhong; Giovanni Appendino; Alberto Minassi; Jean Prenen; Orazio Taglialatela-Scafati; Bernd Nilius
Umbellulone modulates TRP channels.
Pflügers Archiv : European journal of physiology 2011;462(6):861-70.
2011: Federica Pollastro; Orazio Taglialatela-Scafati; Marco Allarà; Luciano De Petrocellis; Vincenzo Di Marzo; Eduardo Muñoz; Giovani Appendino
Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).
Journal of natural products 2011;74(9):2019-22.
2011: Giuseppina Chianese; Giorgio Bavestrello; Barbara Calcinai; Henny A Dien; Ernesto Fattorusso; Alessia Ligresti; Orazio Taglialatela-Scafati; Vincenzo Di Marzo
Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand.
Steroids 2011;76(10-11):998-1002.
2011: Sandra Gemma; Gianluca Giorgi; Bhupendra P Joshi; Ettore Novellino; Mario Salmona; Luisa Savini; Orazio Taglialatela-Scafati; Pierangela Tripaldi; Silvio Caccia; Giuseppe Campiani; Laura Colombo; Isabella Fiorini; Gianluigi Forloni; Claudia Fracasso; Margherita Brindisi; Stefania Butini
Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils.
Organic & biomolecular chemistry 2011;9(14):5137-48.
2011: Yalda Shokoohinia; Giuseppina Chianese; Behzad Zolfaghari; Seyed Ebrahim Sajjadi; Giovanni Appendino; Orazio Taglialatela-Scafati
Macrocyclic diterpenoids from the Iranian plant Euphorbia bungei Boiss.
Fitoterapia 2011;82(3):317-22.
2011: Giuseppina Chianese; Ernesto Fattorusso; Olapeju O Aiyelaagbe; Paolo Luciano; Heinz C Schröder; Werner E G Müller; Orazio Taglialatela-Scafati
Spirocurcasone, a diterpenoid with a novel carbon skeleton from Jatropha curcas.
Organic letters 2011;13(2):316-9.
2011: Cristina Avonto; Orazio Taglialatela-Scafati; Federica Pollastro; Alberto Minassi; Vincenzo Di Marzo; Luciano De Petrocellis; Giovanni Appendino
An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery?
Angewandte Chemie (International ed. in English) 2011;50(2):467-71.
2011: Gabriella Aviello; Jasna M Canadanovic-Brunet; Natasa Milic; Raffaele Capasso; Ernesto Fattorusso; Orazio Taglialatela-Scafati; Ines Fasolino; Angelo A Izzo; Francesca Borrelli
Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa.
PloS one 2011;6(5):e19628.
2011: Giovanni Appendino; G Chianese; Orazio Taglialatela-Scafati
Cannabinoids: occurrence and medicinal chemistry.
Current medicinal chemistry 2011;18(7):1085-99.
2011: Caterina Fattorusso; Marco Persico; Nicoletta Basilico; Donatella Taramelli; Ernesto Fattorusso; Fernando Scala; Orazio Taglialatela-Scafati
Antimalarials based on the dioxane scaffold of plakortin. A concise synthesis and SAR studies.
Bioorganic & medicinal chemistry 2011;19(1):312-20.
2010: Yalda Shokoohinia; Seyed Ebrahim Sajjadi; Behzad Zolfaghari; Giuseppina Chianese; Giovanni Appendino; Orazio Taglialatela-Scafati
Diterpenoid (poly)esters and a ring A-seco-phorboid from the aerial parts of Euphorbia macroclada Boiss.
Fitoterapia 2010;81(7):884-90.
2010: Giuseppina Chianese; Serge R Yerbanga; Leonardo Lucantoni; Annette Habluetzel; Nicoletta Basilico; Donatella Taramelli; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Antiplasmodial triterpenoids from the fruits of neem, Azadirachta indica.
Journal of natural products 2010;73(8):1448-52.
2010: Caterina Fattorusso; Marco Persico; Barbara Calcinai; Carlo Cerrano; Silvia Parapini; Donatella Taramelli; Ettore Novellino; Adriana Romano; Fernando Scala; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Manadoperoxides A-D from the Indonesian sponge Plakortis cfr. simplex. Further insights on the structure-activity relationships of simple 1,2-dioxane antimalarials.
Journal of natural products 2010;73(6):1138-45.
2010: Sandra Gemma; Emanuele Gabellieri; Salvatore Sanna Coccone; Francesc Martí; Orazio Taglialatela-Scafati; Ettore Novellino; Giuseppe Campiani; Stefania Butini
Synthesis of dihydroplakortin, 6-epi-dihydroplakortin, and their C10-desethyl analogues.
The Journal of organic chemistry 2010;75(7):2333-40.
2010: Orazio Taglialatela-Scafati; Ernesto Fattorusso; Adriana Romano; Fernando Scala; Vincenzo Barone; Paola Cimino; Emiliano Stendardo; Bruno Catalanotti; Marco Persico; Caterina Fattorusso
Insight into the mechanism of action of plakortins, simple 1,2-dioxane antimalarials.
Organic & biomolecular chemistry 2010;8(4):846-56.
2010: Fernando Scala; Ernesto Fattorusso; Marialuisa Menna; Orazio Taglialatela-Scafati; Michelle Tierney; Marcel Kaiser; Deniz Tasdemir
Bromopyrrole alkaloids as lead compounds against protozoan parasites.
Marine drugs 2010;8(7):2162-74.
2009: Rihab F Angawi; Barbara Calcinai; Carlo Cerrano; Henny Adeleida Dien; Ernesto Fattorusso; Fernando Scala; Orazio Taglialatela-Scafati
Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.
Journal of natural products 2009;72(12):2195-8.
2009: Giovanni Appendino; Federica Pollastro; Luisella Verotta; Mauro Ballero; Adriana Romano; Paulina Wyrembek; Katarzyna Szczuraszek; Jerzy W Mozrzymas; Orazio Taglialatela-Scafati
Polyacetylenes from sardinian Oenanthe fistulosa: a molecular clue to risus sardonicus.
Journal of natural products 2009;72(5):962-5.
2009: Giovanni Appendino; Alessia Ligresti; Alberto Minassi; Maria Grazia Cascio; Marco Allarà; Orazio Taglialatela-Scafati; Roger G Pertwee; Luciano De Petrocellis; Vincenzo Di Marzo
Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Journal of medicinal chemistry 2009;52(9):3001-9.
2009: Giovanni Appendino; Orazio Taglialatela-Scafati; Adriana Romano; Federica Pollastro; Cristina Avonto; Patrizia Rubiolo
Genepolide, a sesterpene gamma-lactone with a novel carbon skeleton from mountain wormwood (Artemisia umbelliformis).
Journal of natural products 2009;72(3):340-4.
2009: Ernesto Fattorusso; Orazio Taglialatela-Scafati
Marine antimalarials.
Marine drugs 2009;7(2):130-52.
2008: Ernesto Fattorusso; Paolo Luciano; Adriana Romano; Orazio Taglialatela-Scafati; Giovanni Appendino; Marianna Borriello; Caterina Fattorusso
Stereostructure assignment of medium-sized rings through an NMR-computational combined approach. Application to the new germacranes ketopelenolides C and D.
Journal of natural products 2008;71(12):1988-92.
2008: Sandra Gemma; Giuseppe Campiani; Stefania Butini; Gagan Kukreja; Salvatore Sanna Coccone; Bhupendra P Joshi; Marco Persico; Vito Nacci; Isabella Fiorini; Ettore Novellino; Ernesto Fattorusso; Orazio Taglialatela-Scafati; Luisa Savini; Donatella Taramelli; Nicoletta Basilico; Silvia Parapini; Giulia Morace; Vanessa Yardley; Simon L Croft; Massimiliano Coletta; Stefano Marini; Caterina Fattorusso
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies.
Journal of medicinal chemistry 2008;51(5):1278-94.
2008: Ernesto Fattorusso; Adriana Romano; Fernando Scala; Orazio Taglialatela-Scafati
Simplexidine, a 4-alkylpyridinium alkaloid from the Caribbean sponge Plakortis simplex.
Molecules (Basel, Switzerland) 2008;13(7):1465-71.
2007: Caterina Fattorusso; Emiliano Stendardo; Giovanni Appendino; Ernesto Fattorusso; Paolo Luciano; Adriana Romano; Orazio Taglialatela-Scafati
Artarborol, a nor-caryophyllane sesquiterpene alcohol from Artemisia arborescens. stereostructure assignment through concurrence of NMR data and computational analysis.
Organic letters 2007;9(12):2377-80.
2007: Abdelhakim Ahmed-Belkacem; Sira Macalou; Francesca Borrelli; Raffaele Capasso; Ernesto Fattorusso; Orazio Taglialatela-Scafati; Attilio Di Pietro
Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors.
Journal of medicinal chemistry 2007;50(8):1933-8.
2006: Caterina Fattorusso; Giuseppe Campiani; Bruno Catalanotti; Marco Persico; Nicoletta Basilico; Silvia Parapini; Donatella Taramelli; Claudio Campagnuolo; Ernesto Fattorusso; Adriana Romano; Orazio Taglialatela-Scafati
Endoperoxide derivatives from marine organisms: 1,2-dioxanes of the plakortin family as novel antimalarial agents.
Journal of medicinal chemistry 2006;49(24):7088-94.
2006: Francesca Borrelli; Valeria Ascione; Raffaele Capasso; Angelo A Izzo; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Spasmolytic effects of nonprenylated rotenoid constituents of Boerhaavia diffusa roots.
Journal of natural products 2006;69(6):903-6.
2005: Giovanna Basile; Orazio Taglialatela-Scafati; Gianluca Damonte; Andrea Armirotti; Santina Bruzzone; Lucrezia Guida; Luisa Franco; Cesare Usai; Ernesto Fattorusso; Antonio De Flora; Elena Zocchi
ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14509-14.
2005: Francesca Borrelli; Natasa Milic; Valeria Ascione; Raffaele Capasso; Angelo A Izzo; Francesco Capasso; Francesca Petrucci; Roberta Valente; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility.
Planta medica 2005;71(10):928-32.
2005: Raymond J Andersen; Orazio Taglialatela-Scafati
Avrainvilloside, a 6-deoxy-6-aminoglucoglycerolipid from the green alga Avrainvillea nigricans.
Journal of natural products 2005;68(9):1428-30.
2005: Claudio Campagnuolo; Ernesto Fattorusso; Francesca Petrucci; Orazio Taglialatela-Scafati; Giovanni Appendino; Nieves Marquez; Eduardo Muñoz
A prenylbisabolane with NF-kappaB inhibiting properties from Cascarilla (Croton eluteria).
Bioorganic & medicinal chemistry 2005;13(13):4238-42.
2005: Giovanni Appendino; Gabriella Aviello; Mauro Ballero; Francesca Borrelli; Ernesto Fattorusso; Francesca Petrucci; Federico U Santelia; Orazio Taglialatela-Scafati
Cytotoxic germacrane sesquiterpenes from the aerial parts of Santolina insularis.
Journal of natural products 2005;68(6):853-7.
2004: Valeria Costantino; Ernesto Fattorusso; Marialuisa Menna; Orazio Taglialatela-Scafati
Chemical diversity of bioactive marine natural products: an illustrative case study.
Current medicinal chemistry 2004;11(13):1671-92.
2004: Ernesto Fattorusso; Orazio Taglialatela-Scafati; Francesca Petrucci; Giorgio Bavestrello; Barbara Calcinai; Carlo Cerrano; Paola Di Meglio; ANGELA IANARO
Polychlorinated androstanes from the burrowing sponge Cliona nigricans.
Organic letters 2004;6(10):1633-5.
2004: Giovanni Appendino; Federica Bianchi; Ammar Bader; Claudio Campagnuolo; Ernesto Fattorusso; Orazio Taglialatela-Scafati; Magdalena Blanco-Molina; Antonio Macho; Bernd L Fiebich; Paul Bremner; Michael Heinrich; Mauro Ballero; Eduardo Muñoz
Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin.
Journal of natural products 2004;67(4):532-6.
2004: Ernesto Fattorusso; Federico U Santelia; Giovanni Appendino; Mauro Ballero; Orazio Taglialatela-Scafati
Polyoxygenated eudesmanes and trans-chrysanthemanes from the aerial parts of Santolina insularis.
Journal of natural products 2004;67(1):37-41.
2003: Giovanni Appendino; Francesca Borrelli; Raffaele Capasso; Claudio Campagnuolo; Ernesto Fattorusso; Francesca Petrucci; Orazio Taglialatela-Scafati
Minor diterpenoids from cascarilla (Croton eluteria Bennet) and evaluation of the cascarilla extract and cascarillin effects on gastric acid secretion.
Journal of agricultural and food chemistry 2003;51(24):6970-4.
2003: Gabriella Corea; Ernesto Fattorusso; Virginia Lanzotti; Orazio Taglialatela-Scafati; Giovanni Appendino; Mauro Ballero; Pierre-Noël Simon; Charles Dumontet; Attilio Di Pietro
Modified jatrophane diterpenes as modulators of multidrug resistance from Euphorbia dendroides L.
Bioorganic & medicinal chemistry 2003;11(23):5221-7.
2003: Gabriella Corea; Ernesto Fattorusso; Virginia Lanzotti; Orazio Taglialatela-Scafati; Giovanni Appendino; Mauro Ballero; Pierre-Noël Simon; Charles Dumontet; Attilio Di Pietro
Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead.
Journal of medicinal chemistry 2003;46(15):3395-402.
2003: Claudio Campagnuolo; Caterina Fattorusso; Ernesto Fattorusso; ANGELA IANARO; Barbara Pisano; Orazio Taglialatela-Scafati
Simplakidine A, a unique pyridinium alkaloid from the Caribbean sponge plakortis simplex.
Organic letters 2003;5(5):673-6.
2002: Ernesto Fattorusso; Silvia Parapini; Claudio Campagnuolo; Nicoletta Basilico; Orazio Taglialatela-Scafati; Donatella Taramelli
Activity against Plasmodium falciparum of cycloperoxide compounds obtained from the sponge Plakortis simplex.
The Journal of antimicrobial chemotherapy 2002;50(6):883-8.
2002: Orazio Taglialatela-Scafati; Urmila Deo-Jangra; Martha Campbell; Michel Roberge; Raymond J Andersen
Diterpenoids from cultured Erythropodium caribaeorum.
Organic letters 2002;4(23):4085-8.
2002: Ernesto Fattorusso; Maria Iorizzi; Virginia Lanzotti; Orazio Taglialatela-Scafati
Chemical composition of shallot (Allium ascalonicum Hort.).
Journal of agricultural and food chemistry 2002;50(20):5686-90.
2002: Ernesto Fattorusso; Orazio Taglialatela-Scafati; Claudio Campagnuolo; Federico U Santelia; Giovanni Appendino; Paola Spagliardi
Diterpenoids from Cascarilla (Croton eluteria Bennet).
Journal of agricultural and food chemistry 2002;50(18):5131-8.
2001: Ernesto Fattorusso; Virginia Lanzotti; Orazio Taglialatela-Scafati; Carla Cicala
The flavonoids of leek, Allium porrum.
Phytochemistry 2001;57(4):565-9.
2001: Paolo Curir; Marcello Dolci; Virginia Lanzotti; Orazio Taglialatela-Scafati
Kaempferide triglycoside: a possible factor of resistance of carnation (Dianthus caryophyllus) to Fusarium oxysporum f. sp. dianthi.
Phytochemistry 2001;56(7):717-21.
2000: Ernesto Fattorusso; Virginia Lanzotti; Orazio Taglialatela-Scafati; Massimo Di Rosa; ANGELA IANARO
Cytotoxic saponins from bulbs of Allium porrum L.
Journal of agricultural and food chemistry 2000;48(8):3455-62.
1998: F Cafieri; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Novel betaines from the marine sponge Agelas dispar.
Journal of natural products 1998;61(9):1171-3.
1998: F Cafieri; Ernesto Fattorusso; Orazio Taglialatela-Scafati
Novel bromopyrrole alkaloids from the sponge Agelas dispar.
Journal of natural products 1998;61(1):122-5.