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Fabrizio Tagliavini

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Giacomina Rossi; Donatella Conconi; Leda Dalprà; Elena Panzeri; Laura Paoletta; Elena Piccoli; Sara Redaelli; Fabrizio Tagliavini
Mutations in MAPT gene cause chromosome instability and introduce copy number variations widely in the genome.
Maria Luisa Moro; Annemieke Rozemuller; Stefania Saccucci; Andrea Uggetti; Dominic M Walsh; Nenad Bogdanovic; Orso Bugiani; Marcella Catania; Andrea Demarchi; Giuseppe Di Fede; Bernardino Ghetti; Giorgio Giaccone; Antonio Indaco; Raffaella Lombardi; Michela Morbin; Fabrizio Tagliavini
APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.
S Prioni; V Redaelli; A Scaglioni; Paola Soliveri; Fabrizio Tagliavini; F Barocco; Paolo Caffarra; L Concari; C Falcone; Vincenza Fetoni; Simona Gardini; Floriano Girotti
Stereotypic behaviors in degenerative dementias.

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2013: Giacomina Rossi; Donatella Conconi; Leda Dalprà; Elena Panzeri; Laura Paoletta; Elena Piccoli; Sara Redaelli; Fabrizio Tagliavini
Mutations in MAPT gene cause chromosome instability and introduce copy number variations widely in the genome.
Journal of Alzheimer's disease : JAD 2013;33(4):969-82.
2012: Maria Luisa Moro; Annemieke Rozemuller; Stefania Saccucci; Andrea Uggetti; Dominic M Walsh; Nenad Bogdanovic; Orso Bugiani; Marcella Catania; Andrea Demarchi; Giuseppe Di Fede; Bernardino Ghetti; Giorgio Giaccone; Antonio Indaco; Raffaella Lombardi; Michela Morbin; Fabrizio Tagliavini
APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.
Acta neuropathologica 2012;124(6):809-21.
2012: S Prioni; V Redaelli; A Scaglioni; Paola Soliveri; Fabrizio Tagliavini; F Barocco; Paolo Caffarra; L Concari; C Falcone; Vincenza Fetoni; Simona Gardini; Floriano Girotti
Stereotypic behaviors in degenerative dementias.
Journal of neurology 2012;259(11):2452-9.
2012: Fabio Moda; Margherita Ruggerone; Silvia Suardi; Alessandro Terruzzi; Chiara Vimercati; Robert G Will; Pietro Zerbi; Matthew T Bishop; Antonio Brambilla; Ilaria Campagnani; Giuseppe Di Fede; Paolo Fociani; Giorgio Giaccone; Antonio Indaco; Jan Langeveld; Lucia Limido; Jean C Manson; Fabrizio Tagliavini
MM2-thalamic Creutzfeldt-Jakob disease: neuropathological, biochemical and transmission studies identify a distinctive prion strain.
Brain pathology (Zurich, Switzerland) 2012;22(5):662-9.
2012: Matteo Stravalaci; Fabrizio Tagliavini; Michele Mazzanti; Mario Salmona; Antonio Bastone; Marten Beeg; Alfredo Cagnotto; Laura Cantù; Roberto Chiesa; Laura Colombo; Elena Del Favero; Giuseppe Di Fede; Luisa Diomede; Marco Gobbi
Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans.
The Journal of biological chemistry 2012;287(33):27796-805.
2012: gianfranco puoti; Jiri G Safar; Fabrizio Tagliavini; Alberto Bizzi; Gianluigi Forloni; Pierluigi Gambetti
Sporadic human prion diseases: molecular insights and diagnosis.
Lancet neurology 2012;11(7):618-28.
2012: Rona Wilson; Olivier Andreoletti; Thierry Baron; Franco Cardone; cristina casalone; Cristiano Corona; Silvia Graziano; Nora Hunter; Loredana Ingrosso; Richard Lockey; Jean C Manson; Fabio Moda; Chris Plinston; Maurizio Pocchiari; Juergen Richt; Margherita Ruggerone; Marco Sbriccoli; Marion Simmons; Silvia Suardi; Fabrizio Tagliavini; Rona M Barron
Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.
The Journal of general virology 2012;93(Pt 7):1624-9.
2012: Claudio Ruffmann; Damiana Rusconi; Sonia Spinello; Fabrizio Tagliavini; Michela Zini; Manuela Bramerio; Marcello Gambacorta; Stefano Goldwurm; Gianni Pezzoli; Giorgio Giaccone
Lewy body pathology and typical Parkinson disease in a patient with a heterozygous (R275W) mutation in the Parkin gene (PARK2).
Acta neuropathologica 2012;123(6):901-3.
2012: C Ruffmann; Fabrizio Tagliavini; Giacomina Rossi; Manuela Bramerio; Margherita Canesi; Marcello Gambacorta; Giorgio Giaccone; Stefano Goldwurm; G Pezzoli
Atypical tauopathy in a patient with LRRK2-G2019S mutation and tremor-dominant Parkinsonism.
Neuropathology and applied neurobiology 2012;38(4):382-6.
2012: Giacomina Rossi; Mario Salmona; Sarah Sperber; Antonio Bastone; Marten Beeg; Giorgio Giaccone; Giulia Mazzoleni; Michela Morbin; Elena Piccoli; Andrea Uggetti; Fabrizio Tagliavini
New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization.
Neurobiology of aging 2012;33(4):834.e1-6.
2012: Cinzia Coppola; Anna Maria Barbarulo; Giuseppe Di Fede; Carolina Foglia; Elena Piccoli; Giuseppe Piscosquito; Giacomina Rossi; Dario Saracino; Fabrizio Tagliavini; Roberto Cotrufo
A progranulin mutation associated with cortico-basal syndrome in an Italian family expressing different phenotypes of fronto-temporal lobar degeneration.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2012;33(1):93-7.
2012: Silvia Suardi; Chiara Vimercati; Gianluigi Zanusso; Anne Balkema-Buschmann; Ilaria Campagnani; Maria Caramelli; cristina casalone; Marcella Catania; Cristiano Corona; Daniela Gelmetti; Martin H Groschup; Barbara Iulini; Guerino Lombardi; Maria Mazza; Fabio Moda; Salvatore Monaco; Elena Piccoli; Margherita Ruggerone; Fabrizio Tagliavini
Infectivity in skeletal muscle of cattle with atypical bovine spongiform encephalopathy.
PloS one 2012;7(2):e31449.
2011: Ettore Salsano; Roberto Fancellu; Giuseppe Di Fede; Claudia Ciano; Vidmer Scaioli; lorenzo nanetti; Letterio Salvatore Politi; Fabrizio Tagliavini; Caterina Mariotti; Davide Pareyson
Lower limb areflexia without central and peripheral conduction abnormalities is highly suggestive of Gerstmann-Sträussler-Scheinker disease Pro102Leu.
Journal of the neurological sciences 2011;302(1-2):85-8.
2011: Cristina Airoldi; Laura Colombo; Claudia Manzoni; Erika Sironi; Antonino Natalello; Silvia Maria Doglia; Gianluigi Forloni; Fabrizio Tagliavini; Elena Del Favero; Laura Cantù; Francesco Nicotra; Mario Salmona
Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.
Organic & biomolecular chemistry 2011;9(2):463-72.
2011: Giorgio Giaccone; Laura Orsi; Chiara Cupidi; Fabrizio Tagliavini
Lipofuscin hypothesis of Alzheimer's disease.
Dementia and geriatric cognitive disorders extra 2011;1(1):292-6.
2011: Giordana Marcon; Elena Piccoli; Giacomina Rossi; Onelio Geatti; Giorgio Giaccone; Anna Rita Giovagnoli; Marina Grisoli; Vito Toso; Sergio Zanini; Fabrizio Tagliavini
Variability of the clinical phenotype in an Italian family with dementia associated with an intronic deletion in the GRN gene.
Journal of Alzheimer's disease : JAD 2011;26(3):583-90.
2011: Maura Gallo; Silvana Geracitano; Enrico Ghidoni; Giorgio Giaccone; Raffaele Maletta; Norina Marcello; Maria Mirabelli; Gabriella Muraca; Gianfranco Puccio; Nicoletta Smirne; Fabrizio Tagliavini; Franca Vasso; Orso Bugiani; Alessandra Clodomiro; Rosanna Colao; S A M Curcio; Raffaele Di Lorenzo; Francesca Frangipane; Maria Anfossi; Livia Bernardi; Amalia C Bruni
A novel pathogenic PSEN1 mutation in a family with Alzheimer's disease: phenotypical and neuropathological features.
Journal of Alzheimer's disease : JAD 2011;25(3):425-31.
2011: Giacomina Rossi; Elena Piccoli; Luisa Benussi; Francesca Caso; Veronica Redaelli; Giuseppe Magnani; Giuliano Binetti; Roberta Ghidoni; Daniela Perani; Giorgio Giaccone; Fabrizio Tagliavini
A novel progranulin mutation causing frontotemporal lobar degeneration with heterogeneous phenotypic expression.
Journal of Alzheimer's disease : JAD 2011;23(1):7-12.
2010: Simona Binelli; Pamela Agazzi; Laura Canafoglia; Vidmer Scaioli; Ferruccio Panzica; Elisa Visani; Giuseppe Di Fede; Giorgio Giaccone; Alberto Bizzi; Orso Bugiani; Giuliano Avanzini; Fabrizio Tagliavini; Silvana Franceschetti
Myoclonus in Creutzfeldt-Jakob disease: polygraphic and video-electroencephalography assessment of 109 patients.
Movement disorders : official journal of the Movement Disorder Society 2010;25(16):2818-27.
2010: Giorgio Giaccone; Michela Morbin; Fabio Moda; Mario Botta; Giulia Mazzoleni; Andrea Uggetti; Marcella Catania; Maria Luisa Moro; Veronica Redaelli; Alberto Spagnoli; Roberta Simona Rossi; Mario Salmona; Giuseppe Di Fede; Fabrizio Tagliavini
Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.
Acta neuropathologica 2010;120(6):803-12.
2010: Orso Bugiani; Giorgio Giaccone; Giacomina Rossi; Michela Mangieri; Raffaella Capobianco; Michela Morbin; Giulia Mazzoleni; Chiara Cupidi; Giordana Marcon; Annarita Giovagnoli; Alberto Bizzi; Giuseppe Di Fede; gianfranco puoti; F Carella; Andrea Salmaggi; Alessandro Romorini; Giorgio M Patruno; Mauro Magoni; Alessandro Padovani; Fabrizio Tagliavini
Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP.
Archives of neurology 2010;67(8):987-95.
2010: Chiara Cupidi; Raffaella Capobianco; Donato Goffredo; Giordana Marcon; Bernardino Ghetti; Orso Bugiani; Fabrizio Tagliavini; Giorgio Giaccone
Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(1):57-68.
2009: Giordana Marcon; Gianluca Tell; Lorena Perrone; Rita Garbelli; Franco Quadrifoglio; Fabrizio Tagliavini; Giorgio Giaccone
APE1/Ref-1 in Alzheimer's disease: an immunohistochemical study.
Neuroscience letters 2009;466(3):124-7.
2009: Gabriella Marcon; Anna Rita Giovagnoli; Paola Mangiapane; Alessandra Erbetta; Fabrizio Tagliavini; Floriano Girotti
Regression of chronic posterior leukoencephalopathy after stop of methotrexate treatment.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2009;30(5):375-8.
2009: Luca Giliberto; Roberta Borghi; Alessandra Piccini; Rosa Mangerini; Sandro Sorbi; Gabriella Cirmena; Anna Garuti; Bernardino Ghetti; Fabrizio Tagliavini; Mohamed R Mughal; Mark P Mattson; Xiongwei Zhu; Xinglong Wang; Michela Guglielmotto; Elena Tamagno; Massimo Tabaton
Mutant presenilin 1 increases the expression and activity of BACE1.
The Journal of biological chemistry 2009;284(14):9027-38.
2009: Giorgio Giaccone; Marina Grisoli; Lucia Limido; Michela Mangieri; Silvia Suardi; Simona Binelli; Orso Bugiani; Raffaella Capobianco; Giuseppe Di Fede; Paolo Fociani; Fabrizio Tagliavini
A novel phenotype of sporadic Creutzfeldt-Jakob disease.
BMJ case reports 2009;2009():.
2008: Francesca Clerici; A Elia; F Girotti; P Contri; Claudio Mariani; Fabrizio Tagliavini; Gaetana Di Fede
Atypical presentation of Creutzfeldt-Jakob disease: the first Italian case associated with E196K mutation in the PRNP gene.
Journal of the neurological sciences 2008;275(1-2):145-7.
2008: Claudio Mauro; Giorgio Giaccone; G Piscosquito; A Lavorgna; M Nigro; Giuseppe Di Fede; Antonio Leonardi; C Coppola; S Formisano; Fabrizio Tagliavini; Roberto Cotrufo; gianfranco puoti
A novel insertional mutation in the prion protein gene: clinical and bio-molecular findings.
Journal of neurology, neurosurgery, and psychiatry 2008;79(12):1395-8.
2008: Sara Dossena; Luca Imeri; Michela Mangieri; Anna Garofoli; Loris Ferrari; Assunta Senatore; Elena Restelli; Claudia Balducci; Fabio Fiordaliso; Monica Salio; Susanna Bianchi; Luana Fioriti; Michela Morbin; Alessandro Pincherle; Gabriella Marcon; Flavio Villani; Mirjana Carli; Fabrizio Tagliavini; Gianluigi Forloni; Roberto Chiesa
Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.
Neuron 2008;60(4):598-609.
2008: Ugo Cosentino; Demetrio Pitea; Giorgio Moro; Gloria A A Saracino; Pietro Caria; Rosaria M Varì; Laura Colombo; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
The anti-fibrillogenic activity of tetracyclines on PrP 106-126: a 3D-QSAR study.
Journal of molecular modeling 2008;14(10):987-94.
2008: Irina Alafuzoff; Thomas Arzberger; Safa Al-Sarraj; Istvan Bodi; Nenad Bogdanovic; Heiko Braak; Orso Bugiani; Kelly Del Tredici; Isidro Ferrer; Ellen Gelpi; Giorgio Giaccone; Manuel B Graeber; Paul Ince; Wouter Kamphorst; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; Sergey Larionov; David Meyronet; Camelia Monoranu; Piero Parchi; Efstratios Patsouris; Wolfgang Roggendorf; Danielle Seilhean; Fabrizio Tagliavini; Christine Stadelmann; Nathalie Streichenberger; Dietmar R Thal; Stephen B Wharton; Hans A Kretzschmar
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium.
Brain pathology (Zurich, Switzerland) 2008;18(4):484-96.
2008: Antonino Natalello; Valery V Prokorov; Fabrizio Tagliavini; Michela Morbin; Gianluigi Forloni; Marten Beeg; Claudia Manzoni; Laura Colombo; Marco Gobbi; Mario Salmona; Silvia Maria Doglia
Conformational plasticity of the Gerstmann-Sträussler-Scheinker disease peptide as indicated by its multiple aggregation pathways.
Journal of molecular biology 2008;381(5):1349-61.
2008: Giacomina Rossi; Leda Dalprà; Francesca Crosti; Sara Lissoni; Francesca L Sciacca; Marcella Catania; Giuseppe Di Fede; Michela Mangieri; Giorgio Giaccone; Danilo Croci; Fabrizio Tagliavini
A new function of microtubule-associated protein tau: involvement in chromosome stability.
Cell cycle (Georgetown, Tex.) 2008;7(12):1788-94.
2008: Guerino Lombardi; Cristina Casalone; Antonio D' Angelo; Daniela Gelmetti; Gloria Torcoli; Ilaria Barbieri; Cristiano Corona; Elisa Fasoli; Alessia Farinazzo; Michele Fiorini; Matteo Gelati; Barbara Iulini; Fabrizio Tagliavini; Sergio Ferrari; Maria Caramelli; Salvatore Monaco; Lorenzo Capucci; Gianluigi Zanusso
Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes.
PLoS pathogens 2008;4(5):e1000075.
2008: Giacomina Rossi; Cecilia Marelli; Laura Farina; Matilde Laurà; Anna Maria Basile; Claudia Ciano; Fabrizio Tagliavini; Davide Pareyson
The G389R mutation in the MAPT gene presenting as sporadic corticobasal syndrome.
Movement disorders : official journal of the Movement Disorder Society 2008;23(6):892-5.
2008: Paola Piscopo; Gabriella Marcon; Maria Rita Piras; Alessio Crestini; L Malvezzi Campeggi; E Deiana; Rossella Cherchi; F Tanda; A Deplano; Nicola Vanacore; Fabrizio Tagliavini; Maurizio Pocchiari; Giorgio Giaccone; Annamaria Confaloni
A novel PSEN2 mutation associated with a peculiar phenotype.
Neurology 2008;70(17):1549-54.
2008: Ada De Luigi; Laura Colombo; Luisa Diomede; Raffaella Capobianco; Michela Mangieri; Claudia Miccolo; Lucia Limido; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
The efficacy of tetracyclines in peripheral and intracerebral prion infection.
PloS one 2008;3(3):e1888.
2007: Giorgio Giaccone; Giuseppe Di Fede; Michela Mangieri; Lucia Limido; Raffaella Capobianco; Silvia Suardi; Marina Grisoli; Simona Binelli; Paolo Fociani; Orso Bugiani; Fabrizio Tagliavini
A novel phenotype of sporadic Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry 2007;78(12):1379-82.
2007: Ronald S Boshuizen; Michela Morbin; Giulia Mazzoleni; Fabrizio Tagliavini; Rob H Meloen; Johannes P M Langedijk
Polyanion induced fibril growth enables the development of a reproducible assay in solution for the screening of fibril interfering compounds, and the investigation of the prion nucleation site.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(3):205-19.
2007: Raffaella Capobianco; Cristina Casalone; Silvia Suardi; Michela Mangieri; Claudia Miccolo; Lucia Limido; Marcella Catania; Giacomina Rossi; Giuseppe Di Fede; Giorgio Giaccone; Maria Grazia Bruzzone; Ludovico Minati; Cristiano Corona; Pierluigi Acutis; Daniela Gelmetti; Guerino Lombardi; Martin H Groschup; Anne Buschmann; Gianluigi Zanusso; Salvatore Monaco; Maria Caramelli; Fabrizio Tagliavini
Conversion of the BASE prion strain into the BSE strain: the origin of BSE?
PLoS pathogens 2007;3(3):e31.
2007: Luana Fioriti; Nadia Angeretti; Laura Colombo; Ada De Luigi; Alessio Colombo; Claudia Manzoni; Michela Morbin; Fabrizio Tagliavini; Mario Salmona; Roberto Chiesa; Gianluigi Forloni
Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1576-83.
2007: Giuseppe Di Fede; Giorgio Giaccone; Lucia Limido; Michela Mangieri; Silvia Suardi; gianfranco puoti; Michela Morbin; Giulia Mazzoleni; Bernardino Ghetti; Fabrizio Tagliavini
The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease.
Journal of neuropathology and experimental neurology 2007;66(2):124-30.
2006: Gianluca Moroncini; Michela Mangieri; Michela Morbin; Giulia Mazzoleni; Bernardino Ghetti; Armando Gabrielli; R Anthony Williamson; Giorgio Giaccone; Fabrizio Tagliavini
Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.
Neurobiology of disease 2006;23(3):717-24.
2006: Simona Binelli; Pamela Agazzi; Giorgio Giaccone; Robert G Will; Orso Bugiani; Silvana Franceschetti; Fabrizio Tagliavini
Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease.
Annals of neurology 2006;59(2):423-7.
2006: Marco Gobbi; Laura Colombo; Michela Morbin; Giulia Mazzoleni; Elena Accardo; Marco Vanoni; Elena Del Favero; Laura Cantù; Daniel A Kirschner; Claudia Manzoni; Marten Beeg; Paolo Ceci; Paolo Ubezio; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the "dock-and-lock" model.
The Journal of biological chemistry 2006;281(2):843-9.
2006: Anna Rita Giovagnoli; Giordana Marcon; Giorgio Giaccone; Annamaria Confaloni; Fabrizio Tagliavini
Cognitive deficits in familial Alzheimer's disease associated with M239V mutation of presenilin 2.
Dementia and geriatric cognitive disorders 2006;22(3):238-43.
2005: Giorgio Giaccone; Giacomina Rossi; Laura Farina; Giordana Marcon; Giuseppe Di Fede; Marcella Catania; Michela Morbin; Leonardo Sacco; Orso Bugiani; Fabrizio Tagliavini
Familial frontotemporal dementia associated with the novel MAPT mutation T427M.
Journal of neurology 2005;252(12):1543-5.
2005: gianfranco puoti; Giorgio Giaccone; Michela Mangieri; Lucia Limido; Paolo Fociani; Pietro Zerbi; Silvia Suardi; Giacomina Rossi; Selina Iussich; Raffaella Capobianco; Giuseppe Di Fede; Giordana Marcon; Roberto Cotrufo; Graziella Filippini; Orso Bugiani; Fabrizio Tagliavini
Sporadic Creutzfeldt-Jakob disease: the extent of microglia activation is dependent on the biochemical type of PrPSc.
Journal of neuropathology and experimental neurology 2005;64(10):902-9.
2005: Mario Salmona; Raffaella Capobianco; Laura Colombo; Ada De Luigi; Giacomina Rossi; Michela Mangieri; Giorgio Giaccone; Elena Quaglio; Roberto Chiesa; Maria Benedetta Donati; Fabrizio Tagliavini; Gianluigi Forloni
Role of plasminogen in propagation of scrapie.
Journal of virology 2005;79(17):11225-30.
2005: Robert Veerhuis; Ronald S Boshuizen; Michela Morbin; Giulia Mazzoleni; Jeroen J M Hoozemans; Johannes P M Langedijk; Fabrizio Tagliavini; Jan P M Langeveld; Piet Eikelenboom
Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q.
Neurobiology of disease 2005;19(1-2):273-82.
2005: Elisa Visani; Pamela Agazzi; Vidmer Scaioli; Giorgio Giaccone; Simona Binelli; Laura Canafoglia; Ferruccio Panzica; Fabrizio Tagliavini; Orso Bugiani; Giuliano Avanzini; Silvana Franceschetti
FVEPs in Creutzfeldt-Jacob disease: waveforms and interaction with the periodic EEG pattern assessed by single sweep analysis.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2005;116(4):895-904.
2005: Claudio Soto; Laurence Anderes; Silvia Suardi; Franco Cardone; Joaquin Castilla; Marie-José Frossard; Sergio Peano; Paula Saá; Lucia Limido; Michaela Carbonatto; James Ironside; Juan-Maria Torres; Maurizio Pocchiari; Fabrizio Tagliavini
Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.
FEBS letters 2005;579(3):638-42.
2004: Giacomina Rossi; Giorgio Giaccone; Raffaele Maletta; Michela Morbin; Raffaella Capobianco; Michela Mangieri; Anna Rita Giovagnoli; A Bizzi; Carmine Tomaino; Maria Perri; Manuela Di Natale; Fabrizio Tagliavini; Orso Bugiani; Amalia C Bruni
A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene.
Neurology 2004;63(5):910-2.
2004: gianfranco puoti; Lucia Limido; Roberto Cotrufo; Giuseppe Di Fede; Fabrizio Tagliavini
Sporadic Creutzfeldt-Jakob disease with MM1-type prion protein and plaques.
Neurology 2004;62(7):1239; author reply 1239.
2004: Cristina Casalone; Gianluigi Zanusso; Pierluigi Acutis; Sergio Ferrari; Lorenzo Capucci; Fabrizio Tagliavini; Salvatore Monaco; Maria Caramelli
Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3065-70.
2004: Giordana Marcon; Giorgio Giaccone; Chiara Cupidi; Matteo Balestrieri; Carlo Alberto Beltrami; Nicoletta Finato; Paolo Bergonzi; Sandro Sorbi; Orso Bugiani; Fabrizio Tagliavini
Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.
Journal of neuropathology and experimental neurology 2004;63(3):199-209.
2004: Giacomina Rossi; Elisabetta Gasparoli; Claudio Pasquali; Giuseppe Di Fede; Daniela Testa; Alberto Albanese; Fulvio Bracco; Fabrizio Tagliavini
Progressive supranuclear palsy and Parkinson's disease in a family with a new mutation in the tau gene.
Annals of neurology 2004;55(3):448.
2004: Massimo Tabaton; Salvatore Monaco; Maria Paola Cordone; Monica Colucci; Giorgio Giaccone; Fabrizio Tagliavini; Gianluigi Zanusso
Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease.
Annals of neurology 2004;55(2):294-6.
2003: Mario Salmona; Michela Morbin; Tania Massignan; Laura Colombo; Giulia Mazzoleni; Raffaella Capobianco; Luisa Diomede; Florian Thaler; Luca Mollica; Giovanna Musco; Joseph J Kourie; Orso Bugiani; Deepak Sharma; Hideyo Inouye; Daniel A Kirschner; Gianluigi Forloni; Fabrizio Tagliavini
Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.
The Journal of biological chemistry 2003;278(48):48146-53.
2003: Vladimiro Pietrini; gianfranco puoti; Lucia Limido; Giacomina Rossi; Giuseppe Di Fede; Giorgio Giaccone; Michela Mangieri; F Tedeschi; A Bondavalli; Domenico Mancia; Orso Bugiani; Fabrizio Tagliavini
Creutzfeldt-Jakob disease with a novel extra-repeat insertional mutation in the PRNP gene.
Neurology 2003;61(9):1288-91.
2003: Agnès Barret; Fabrizio Tagliavini; Gianluigi Forloni; Clive Bate; Mario Salmona; Laura Colombo; Ada De Luigi; Lucia Limido; Silvia Suardi; Giacomina Rossi; Frédéric Auvré; Karim Adjou; Nicole Salès; Alun Williams; Corinne Ida Lasmézas; Jean-Philippe Deslys
Evaluation of quinacrine treatment for prion diseases.
Journal of virology 2003;77(15):8462-9.
2003: Bernardino Ghetti; Fabrizio Tagliavini; M Takao; Orso Bugiani; Pedro Piccardo
Hereditary prion protein amyloidoses.
Clinics in laboratory medicine 2003;23(1):65-85, viii.
2003: Robert Veerhuis; Mariëlle J Van Breemen; Jeroen M Hoozemans; Michela Morbin; Jamal Ouladhadj; Fabrizio Tagliavini; Piet Eikelenboom
Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro.
Acta neuropathologica 2003;105(2):135-44.
2002: Valentina Bonetto; Tania Massignan; Roberto Chiesa; Michela Morbin; Giulia Mazzoleni; Luisa Diomede; Nadia Angeretti; Laura Colombo; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Synthetic miniprion PrP106.
The Journal of biological chemistry 2002;277(35):31327-34.
2002: Gianluigi Forloni; Selina Iussich; Tazeen Awan; Laura Colombo; Nadia Angeretti; Laura Girola; Ilaria Bertani; Giorgio Poli; Maria Caramelli; Maria Grazia Bruzzone; Laura Farina; Lucia Limido; Giacomina Rossi; Giorgio Giaccone; James W Ironside; Orso Bugiani; Mario Salmona; Fabrizio Tagliavini
Tetracyclines affect prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10849-54.
2002: Alessandro Corsaro; Stefano Thellung; Claudio Russo; Valentina Villa; Sara Arena; M C D'Adamo; Domenico Paludi; D Rossi Principe; Gianluca Damonte; Umberto Benatti; Antonio Aceto; Fabrizio Tagliavini; Gennaro Schettini; Tullio Florio
Expression in E. coli and purification of recombinant fragments of wild type and mutant human prion protein.
Neurochemistry international 2002;41(1):55-63.
2002: Stefano Thellung; Valentina Villa; Alessandro Corsaro; Sara Arena; Enrico Millo; Gianluca Damonte; Umberto Benatti; Fabrizio Tagliavini; Tullio Florio; Gennaro Schettini
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
Neurobiology of disease 2002;9(1):69-81.
2001: Masaki Takao; Bernardino Ghetti; Jill R Murrell; Frederick W Unverzagt; G Giaccone; Fabrizio Tagliavini; Orso Bugiani; Pedro Piccardo; Christine M Hulette; Barbara J Crain; Martin R Farlow; Albert Heyman
Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures.
Journal of neuropathology and experimental neurology 2001;60(12):1137-52.
2001: Pedro Piccardo; Juris J Liepnieks; A William; Stephen R Dlouhy; Martin R Farlow; K Young; David Nochlin; Thomas D Bird; R R Nixon; Melvyn Ball; Charles DeCarli; Orso Bugiani; Fabrizio Tagliavini; M D Benson; Bernardino Ghetti
Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations.
The American journal of pathology 2001;158(6):2201-7.
2001: Fabrizio Tagliavini; PM Lievens; C Tranchant; J M Warter; M Mohr; Giorgio Giaccone; F Perini; Giacomina Rossi; Mario Salmona; Pedro Piccardo; Bernardino Ghetti; Ronald C Beavis; Orso Bugiani; Blas Frangione; Frances Prelli
A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V.
The Journal of biological chemistry 2001;276(8):6009-15.
2001: Gianluigi Forloni; Laura Colombo; Laura Girola; Fabrizio Tagliavini; Mario Salmona
Anti-amyloidogenic activity of tetracyclines: studies in vitro.
FEBS letters 2001;487(3):404-7.
2001: Fabrizio Tagliavini; Gianluigi Forloni; P D'Ursi; Orso Bugiani; M Salmona
Studies on peptide fragments of prion proteins.
Advances in protein chemistry 2001;57():171-201.
2001: Efrat Levy; Magdalena Sastre; Asok Kumar; G Gallo; Pedro Piccardo; Bernardino Ghetti; Fabrizio Tagliavini
Codeposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients.
Journal of neuropathology and experimental neurology 2001;60(1):94-104.
2000: Stéphane Haïk; Jean-Michel Peyrin; laurence lins; M Y Rosseneu; R Brasseur; J P Langeveld; Fabrizio Tagliavini; Jean-Philippe Deslys; Corinne Ida Lasmézas; Dominique Dormont
Neurotoxicity of the putative transmembrane domain of the prion protein.
Neurobiology of disease 2000;7(6 Pt B):644-56.
2000: Leticia Miravalle; T Tokuda; Roberto Chiarle; G Giaccone; O Bugiani; Fabrizio Tagliavini; Blas Frangione; Jorge Ghiso
Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.
The Journal of biological chemistry 2000;275(35):27110-6.
2000: Giacomina Rossi; Giorgio Giaccone; L Giampaolo; Selina Iussich; gianfranco puoti; Maura Frigo; Guido Cavaletti; Lodovico Frattola; Orso Bugiani; Fabrizio Tagliavini
Creutzfeldt-Jakob disease with a novel four extra-repeat insertional mutation in the PrP gene.
Neurology 2000;55(3):405-10.
2000: Stefano Thellung; Tullio Florio; Valentina Villa; Alessandro Corsaro; Sara Arena; C Amico; Mauro Robello; M Salmona; G Forloni; O Bugiani; Fabrizio Tagliavini; Gennaro Schettini
Apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in rat cerebellar granule cells treated with the prion protein fragment 106-126.
Neurobiology of disease 2000;7(4):299-309.
2000: gianfranco puoti; Giacomina Rossi; Giorgio Giaccone; Tazeen Awan; PM Lievens; C A Defanti; Fabrizio Tagliavini; Orso Bugiani
Polymorphism at codon 129 of PRNP affects the phenotypic expression of Creutzfeldt-Jakob disease linked to E200K mutation.
Annals of neurology 2000;48(2):269-70.
2000: Fabrizio Tagliavini; Gianluigi Forloni; Laura Colombo; Giacomina Rossi; Laura Girola; B Canciani; Nadia Angeretti; L Giampaolo; E Peressini; Tazeen Awan; Luca De Gioia; Enzio Ragg; Orso Bugiani; Mario Salmona
Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro.
Journal of molecular biology 2000;300(5):1309-22.
2000: Orso Bugiani; G Giaccone; Pedro Piccardo; Michela Morbin; Fabrizio Tagliavini; Bernardino Ghetti
Neuropathology of Gerstmann-Sträussler-Scheinker disease.
Microscopy research and technique 2000;50(1):10-5.
2000: Stefano Thellung; Tullio Florio; Alessandro Corsaro; Sara Arena; M Merlino; M Salmona; Fabrizio Tagliavini; O Bugiani; G Forloni; Gennaro Schettini
Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(4-5):481-92.
2000: Gianluigi Forloni; Mario Salmona; O Bugiani; Fabrizio Tagliavini
Comment on: Neurotoxicity of prion peptide 106-126 not confirmed, by Beat Kunz, Erika Sandmeier, Philipp Christen. FEBS Letters 485 (1999) 65-68.
FEBS letters 2000;466(1):205-6; discussion 207.
2000: Claudio Soto; R J Kascsak; GP Saborío; Pierre Aucouturier; Thomas Wisniewski; Frances Prelli; Richard J Kascsak; E Mendez; D A Harris; James Ironside; Fabrizio Tagliavini; Richard I Carp; Blas Frangione
Reversion of prion protein conformational changes by synthetic beta-sheet breaker peptides.
Lancet 2000;355(9199):192-7.
2000: Giorgio Giaccone; B Canciani; gianfranco puoti; Giacomina Rossi; D Goffredo; Selina Iussich; Paolo Fociani; Fabrizio Tagliavini; Orso Bugiani
Creutzfeldt-Jakob disease: Carnoy's fixative improves the immunohistochemistry of the proteinase K-resistant prion protein.
Brain pathology (Zurich, Switzerland) 2000;10(1):31-7.
1999: gianfranco puoti; Giorgio Giaccone; Giacomina Rossi; B Canciani; Orso Bugiani; Fabrizio Tagliavini
Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain.
Neurology 1999;53(9):2173-6.
1999: Enzio Ragg; Fabrizio Tagliavini; P Malesani; L Monticelli; Orso Bugiani; Gianluigi Forloni; Mario Salmona
Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics.
European journal of biochemistry / FEBS 1999;266(3):1192-201.
1999: Mario Salmona; P Malesani; Luca De Gioia; S Gorla; M Bruschi; A Molinari; F Della Vedova; B Pedrotti; M A Marrari; Tazeen Awan; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini
Molecular determinants of the physicochemical properties of a critical prion protein region comprising residues 106-126.
The Biochemical journal 1999;342 ( Pt 1)():207-14.
1999: Orso Bugiani; Jill R Murrell; Giorgio Giaccone; M Hasegawa; G Ghigo; Massimo Tabaton; Michela Morbin; Alberto Primavera; F Carella; Claudio Solaro; Marina Grisoli; Mario Savoiardo; Maria Grazia Spillantini; Fabrizio Tagliavini; Michel Goedert; Bernardino Ghetti
Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.
Journal of neuropathology and experimental neurology 1999;58(6):667-77.
1999: Giordana Marcon; G Giaccone; B Canciani; L Cajola; G Rossi; Luca De Gioia; M Salmona; Orso Bugiani; Fabrizio Tagliavini
A betaPP peptide carboxyl-terminal to Abeta is neurotoxic.
The American journal of pathology 1999;154(4):1001-7.
1999: Jean-Michel Peyrin; Corinne Ida Lasmézas; Stéphane Haïk; Fabrizio Tagliavini; M Salmona; A Williams; D Richie; Jean-Philippe Deslys; Dominique Dormont
Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines.
Neuroreport 1999;10(4):723-9.
1998: Tullio Florio; Stefano Thellung; C Amico; Mauro Robello; M Salmona; O Bugiani; Fabrizio Tagliavini; G Forloni; Gennaro Schettini
Prion protein fragment 106-126 induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell line.
Journal of neuroscience research 1998;54(3):341-52.
1998: Adolfo Jiménez-Huete; PM Lievens; Ruben Vidal; Pedro Piccardo; Bernardino Ghetti; Fabrizio Tagliavini; Blas Frangione; Frances Prelli
Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues.
The American journal of pathology 1998;153(5):1561-72.
1998: Pedro Piccardo; Stephen R Dlouhy; PM Lievens; K Young; Thomas D Bird; David Nochlin; dennis dickson; Harry V Vinters; T R Zimmerman; I R Mackenzie; Stephen J Kish; Lee Cyn Ang; Charles DeCarli; Maurizio Pocchiari; Paul Brown; CJ Gibbs; D Carleton Gajdusek; Orso Bugiani; James Ironside; Fabrizio Tagliavini; Bernardino Ghetti
Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity.
Journal of neuropathology and experimental neurology 1998;57(10):979-88.
1998: Pedro Piccardo; J P Langeveld; Andrew Hill; Stephen R Dlouhy; K Young; G Giaccone; G Rossi; M Bugiani; Orso Bugiani; R H Meloen; J Collinge; Fabrizio Tagliavini; Bernardino Ghetti
An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy.
The American journal of pathology 1998;152(6):1415-20.
1998: Giacomina Rossi; G Macchi; M Porro; Giorgio Giaccone; M Bugiani; E Scarpini; G Scarlato; G E Molini; F Sasanelli; Orso Bugiani; Fabrizio Tagliavini
Fatal familial insomnia: genetic, neuropathologic, and biochemical study of a patient from a new Italian kindred.
Neurology 1998;50(3):688-92.
1997: G Macchi; G Rossi; A L Abbamondi; Giorgio Giaccone; Domenico Mancia; Fabrizio Tagliavini; Orso Bugiani
Diffuse thalamic degeneration in fatal familial insomnia. A morphometric study.
Brain research 1997;771(1):154-8.
1997: Fabrizio Tagliavini; Robert McArthur; B Canciani; Giorgio Giaccone; M Porro; M Bugiani; PM Lievens; Orso Bugiani; E Peri; Paola Dall'Ara; Mara Rocchi; Giorgio Poli; Gianluigi Forloni; T Bandiera; Mario Varasi; A Suarato; P Cassutti; MA Cervini; J Lansen; Mario Salmona; C Post
Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.
Science (New York, N.Y.) 1997;276(5315):1119-22.
1997: Mario Salmona; Gianluigi Forloni; Luisa Diomede; M Algeri; Luca De Gioia; Nadia Angeretti; Giorgio Giaccone; Fabrizio Tagliavini; Orso Bugiani
A neurotoxic and gliotrophic fragment of the prion protein increases plasma membrane microviscosity.
Neurobiology of disease 1997;4(1):47-57.
1996: Luisa Diomede; Silvano Sozzani; Walter Luini; M Algeri; Luca De Gioia; R Chiesa; PM Lievens; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Activation effects of a prion protein fragment [PrP-(106-126)] on human leucocytes.
The Biochemical journal 1996;320 ( Pt 2)():563-70.
1996: Pedro Piccardo; C Seiler; Stephen R Dlouhy; K Young; Martin R Farlow; F Prelli; Blas Frangione; Orso Bugiani; Fabrizio Tagliavini; Bernardino Ghetti
Proteinase-K-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease (Indiana kindred).
Journal of neuropathology and experimental neurology 1996;55(11):1157-63.
1996: Gianluigi Forloni; Fabrizio Tagliavini; Orso Bugiani; Mario Salmona
Amyloid in Alzheimer's disease and prion-related encephalopathies: studies with synthetic peptides.
Progress in neurobiology 1996;49(4):287-315.
1996: F Perini; Ruben Vidal; Bernardino Ghetti; Fabrizio Tagliavini; Blas Frangione; F Prelli
PrP27-30 is a normal soluble prion protein fragment released by human platelets.
Biochemical and biophysical research communications 1996;223(3):572-7.
1996: Bernardino Ghetti; Pedro Piccardo; Blas Frangione; Orso Bugiani; Giorgio Giaccone; K Young; F Prelli; Martin R Farlow; Stephen R Dlouhy; Fabrizio Tagliavini
Prion protein amyloidosis.
Brain pathology (Zurich, Switzerland) 1996;6(2):127-45.
1996: Roberto Chiesa; Nadia Angeretti; E Lucca; Mario Salmona; Fabrizio Tagliavini; Orso Bugiani; Gianluigi Forloni
Clusterin (SGP-2) induction in rat astroglial cells exposed to prion protein fragment 106-126.
The European journal of neuroscience 1996;8(3):589-97.
1996: Bernardino Ghetti; Pedro Piccardo; Maria Grazia Spillantini; Y Ichimiya; M Porro; F Perini; T Kitamoto; J Tateishi; C Seiler; Blas Frangione; Orso Bugiani; Giorgio Giaccone; F Prelli; Michel Goedert; Stephen R Dlouhy; Fabrizio Tagliavini
Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):744-8.
1996: Giorgio Giaccone; B Pedrotti; antonio migheli; L Verga; J Perez; G Racagni; Mark A. Smith; George Perry; Luca De Gioia; C Selvaggini; Mario Salmona; Jorge Ghiso; Blas Frangione; K Islam; Orso Bugiani; Fabrizio Tagliavini
beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease.
The American journal of pathology 1996;148(1):79-87.
1995: Pedro Piccardo; Bernardino Ghetti; dennis dickson; Harry V Vinters; Giorgio Giaccone; Orso Bugiani; Fabrizio Tagliavini; K Young; Stephen R Dlouhy; C Seiler
Gerstmann-Sträussler-Scheinker disease (PRNP P102L): amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165.
Journal of neuropathology and experimental neurology 1995;54(6):790-801.
1995: Orso Bugiani; Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Khalid H El Hachimi; J F Foncin; Blas Frangione
Diffuse senile plaques: amorphous or fibrous?
The American journal of pathology 1995;146(3):777-9.
1995: Bernardino Ghetti; Stephen R Dlouhy; Giorgio Giaccone; Orso Bugiani; Blas Frangione; Martin R Farlow; Fabrizio Tagliavini
Gerstmann-Sträussler-Scheinker disease and the Indiana kindred.
Brain pathology (Zurich, Switzerland) 1995;5(1):61-75.
1994: Fabrizio Tagliavini; F Prelli; M Porro; Giacomina Rossi; Giorgio Giaccone; Martin R Farlow; Stephen R Dlouhy; Bernardino Ghetti; Orso Bugiani; Blas Frangione
Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele.
Cell 1994;79(4):695-703.
1994: Martin R Farlow; Bernardino Ghetti; Stephen R Dlouhy; Giorgio Giaccone; Orso Bugiani; Fabrizio Tagliavini; S Wagner
Cerebrospinal fluid levels of amyloid beta-protein precursor are low in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Neurology 1994;44(8):1508-10.
1994: Luca De Gioia; C Selvaggini; Elena Ghibaudi; Luisa Diomede; Orso Bugiani; Gianluigi Forloni; Fabrizio Tagliavini; Mario Salmona
Conformational polymorphism of the amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein.
The Journal of biological chemistry 1994;269(11):7859-62.
1994: Bernardino Ghetti; Fabrizio Tagliavini; Giorgio Giaccone; Orso Bugiani; Blas Frangione; Martin R Farlow; Stephen R Dlouhy
Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles.
Molecular neurobiology 1994;8(1):41-8.
1993: Fabrizio Tagliavini; F Prelli; L Verga; Giorgio Giaccone; R Sarma; P Gorevic; Bernardino Ghetti; F Passerini; Elena Ghibaudi; Gianluigi Forloni
Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9678-82.
1993: C Selvaggini; Luca De Gioia; L Cantù; Elena Ghibaudi; Luisa Diomede; F Passerini; Gianluigi Forloni; Orso Bugiani; Fabrizio Tagliavini; Mario Salmona
Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein.
Biochemical and biophysical research communications 1993;194(3):1380-6.
1993: Fabrizio Tagliavini; Giorgio Giaccone; F Prelli; L Verga; M Porro; John Q Trojanowski; Martin R Farlow; Blas Frangione; Bernardino Ghetti; Orso Bugiani
A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Brain research 1993;616(1-2):325-9.
1993: Gianluigi Forloni; Roberto Chiesa; S Smiroldo; L Verga; Mario Salmona; Fabrizio Tagliavini; Nadia Angeretti
Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35.
Neuroreport 1993;4(5):523-6.
1993: Gianluigi Forloni; Nadia Angeretti; Roberto Chiesa; E Monzani; Mario Salmona; Orso Bugiani; Fabrizio Tagliavini
Neurotoxicity of a prion protein fragment.
Nature 1993;362(6420):543-6.
1993: Fabrizio Tagliavini; Giorgio Giaccone; Orso Bugiani; Blas Frangione
Ubiquitinated neurites are associated with preamyloid and cerebral amyloid beta deposits in patients with hereditary cerebral hemorrhage with amyloidosis Dutch type.
Acta neuropathologica 1993;85(3):267-71.
1993: Orso Bugiani; Giorgio Giaccone; L Verga; Bianca Pollo; Blas Frangione; Martin R Farlow; Fabrizio Tagliavini; Bernardino Ghetti
Beta PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Journal of neuropathology and experimental neurology 1993;52(1):64-70.
1992: Giorgio Giaccone; L Verga; Orso Bugiani; Blas Frangione; D Serban; Stanley B Prusiner; Martin R Farlow; Bernardino Ghetti; Fabrizio Tagliavini
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9349-53.
1992: F Carella; Vincenza Fetoni; Bianca Pollo; Daniela Testa; Fabrizio Tagliavini; Floriano Girotti
Sneddon's syndrome and renal carcinoma. Case report.
Functional neurology 1992;7(5):395-400.
1992: Fabrizio Tagliavini; F Prelli; M Porro; Mario Salmona; Orso Bugiani; Blas Frangione
A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies.
Biochemical and biophysical research communications 1992;184(3):1398-404.
1992: Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Blas Frangione; Orso Bugiani
Down syndrome as a key to the time sequence of brain changes in Alzheimer disease.
Progress in clinical and biological research 1992;379():143-58.
1991: Khalid H El Hachimi; L Verga; Giorgio Giaccone; Fabrizio Tagliavini; Blas Frangione; Orso Bugiani; Jean Francois Foncin
Relationship between non-fibrillary amyloid precursors and cell processes in the cortical neuropil of Alzheimer patients.
Neuroscience letters 1991;129(1):119-22.
1991: Fabrizio Tagliavini; Giorgio Giaccone; L Verga; Jorge Ghiso; Blas Frangione; Orso Bugiani
Alzheimer patients: preamyloid deposits are immunoreactive with antibodies to extracellular domains of the amyloid precursor protein.
Neuroscience letters 1991;128(1):117-20.
1991: Fabrizio Tagliavini; F Prelli; Jorge Ghiso; Orso Bugiani; D Serban; Stanley B Prusiner; Martin R Farlow; Bernardino Ghetti; Blas Frangione
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
The EMBO journal 1991;10(3):513-9.
1990: Orso Bugiani; Giorgio Giaccone; L Verga; Bianca Pollo; Bernardino Ghetti; Blas Frangione; Fabrizio Tagliavini
Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits.
Neuroscience letters 1990;119(1):56-9.
1990: Giorgio Giaccone; Fabrizio Tagliavini; L Verga; Blas Frangione; Martin R Farlow; Orso Bugiani; Bernardino Ghetti
Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease.
Brain research 1990;530(2):325-9.
1990: W F Timmers; Fabrizio Tagliavini; J Haan; Blas Frangione
Parenchymal preamyloid and amyloid deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis--Dutch type.
Neuroscience letters 1990;118(2):223-6.
1990: Giorgio Giaccone; L Verga; M Finazzi; Bianca Pollo; Fabrizio Tagliavini; Blas Frangione; Orso Bugiani
Cerebral preamyloid deposits and congophilic angiopathy in aged dogs.
Neuroscience letters 1990;114(2):178-83.
1990: Fabrizio Tagliavini; Jorge Ghiso; W F Timmers; G Giaccone; O Bugiani; Blas Frangione
Coexistence of Alzheimer's amyloid precursor protein and amyloid protein in cerebral vessel walls.
Laboratory investigation; a journal of technical methods and pathology 1990;62(6):761-7.
1989: L Verga; Blas Frangione; Fabrizio Tagliavini; Giorgio Giaccone; antonio migheli; Orso Bugiani
Alzheimer patients and Down patients: cerebral preamyloid deposits differ ultrastructurally and histochemically from the amyloid of senile plaques.
Neuroscience letters 1989;105(3):294-9.
1989: Bernardino Ghetti; Fabrizio Tagliavini; Colin L Masters; Konrad Beyreuther; Giorgio Giaccone; L Verga; Martin R Farlow; P M Conneally; Stephen R Dlouhy; Biagio Azzarelli
Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family.
Neurology 1989;39(11):1453-61.
1989: Orso Bugiani; Giorgio Giaccone; Blas Frangione; Bernardino Ghetti; Fabrizio Tagliavini
Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system.
Neuroscience letters 1989;103(3):263-8.
1989: Jorge Ghiso; Fabrizio Tagliavini; W F Timmers; Blas Frangione
Alzheimer's disease amyloid precursor protein is present in senile plaques and cerebrospinal fluid: immunohistochemical and biochemical characterization.
Biochemical and biophysical research communications 1989;163(1):430-7.
1989: Giorgio Giaccone; Fabrizio Tagliavini; G Linoli; Constantin Bouras; L Frigerio; Blas Frangione; Orso Bugiani
Down patients: extracellular preamyloid deposits precede neuritic degeneration and senile plaques.
Neuroscience letters 1989;97(1-2):232-8.
1989: Fabrizio Tagliavini; Giorgio Giaccone; G Linoli; Blas Frangione; Orso Bugiani
Cerebral extracellular preamyloid deposits in Alzheimer's disease, Down syndrome and nondemented elderly individuals.
Progress in clinical and biological research 1989;317():1001-5.
1988: Fabrizio Tagliavini; Giorgio Giaccone; Blas Frangione; Orso Bugiani
Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals.
Neuroscience letters 1988;93(2-3):191-6.
1988: Giorgio Giaccone; Fabrizio Tagliavini; J S Street; Bernardino Ghetti; Orso Bugiani
Progressive supranuclear palsy with hypertrophy of the olives. An immunocytochemical study of the cytoskeleton of argyrophilic neurons.
Acta neuropathologica 1988;77(1):14-20.