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Hsin-Hsiung Tai

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Xiuling Li; Hsin-Hsiung Tai
Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells.
Xiuling Li; Hsin-Hsiung Tai
Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells.
Hsin-Hsiung Tai; Xiuling Chi; Min Tong
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).

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All Publications

2013: Xiuling Li; Hsin-Hsiung Tai
Activation of thromboxane A2 receptor (TP) increases the expression of monocyte chemoattractant protein -1 (MCP-1)/chemokine (C-C motif) ligand 2 (CCL2) and recruits macrophages to promote invasion of lung cancer cells.
PloS one 2013;8(1):e54073.
2012: Xiuling Li; Hsin-Hsiung Tai
Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells.
Current cancer drug targets 2012;12(6):703-15.
2011: Hsin-Hsiung Tai; Xiuling Chi; Min Tong
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Prostaglandins & other lipid mediators 2011;96(1-4):37-40.
2011: Adel Hamza; Hsin-Hsiung Tai; Min Tong; Xinyun Zhao; Chang-Guo Zhan
Novel human mPGES-1 inhibitors identified through structure-based virtual screening.
Bioorganic & medicinal chemistry 2011;19(20):6077-86.
2011: Ying Wu; Cheol Hee Choi; Chul Ho Jang; Sandeep Karna; Dong Hee Na; Hsin-Hsiung Tai; Min Tong; Hoon Cho
Synthesis and biological evaluation of novel thiazolidinedione analogues as 15-hydroxyprostaglandin dehydrogenase inhibitors.
Journal of medicinal chemistry 2011;54(14):5260-4.
2011: Liu Xue; Mei-Chuan Ko; Min Tong; Wenchao Yang; Shurong Hou; Lei Fang; Junjun Liu; Fang Zheng; James H Woods; Hsin-Hsiung Tai; Chang-Guo Zhan
Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.
Molecular pharmacology 2011;79(2):290-7.
2010: Xiuling Chi; Hsin-Hsiung Tai
Interleukin-4 up-regulates 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in human lung cancer cells.
Experimental cell research 2010;316(14):2251-9.
2010: Jingyan Wei; Weili Yan; Xiuling Li; Yunfei Ding; Hsin-Hsiung Tai
Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells.
Lung cancer (Amsterdam, Netherlands) 2010;69(1):26-32.
2010: Yuhua Zhao; Chu-Chun Weng; Min Tong; Jingyan Wei; Hsin-Hsiung Tai
Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo.
Lung cancer (Amsterdam, Netherlands) 2010;68(2):161-9.
2010: Ying Wu; Hsin-Hsiung Tai; Hoon Cho
Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors.
Bioorganic & medicinal chemistry 2010;18(4):1428-33.
2009: Akira Miyaki; Peiying Yang; Hsin-Hsiung Tai; Kotha Subbaramaiah; Andrew J Dannenberg
Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(3):G559-66.
2009: Xiuling Li; Hsin-Hsiung Tai
Activation of thromboxane A(2) receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells.
Carcinogenesis 2009;30(9):1606-13.
2009: Alexandra Thiel; Aparna Ganesan; Johanna Mrena; Siina Junnila; Antti Nykänen; Annabrita Hemmes; Hsin-Hsiung Tai; Outi Monni; Arto Kokkola; Caj Haglund; Tatiana V Petrova; Ari Ristimäki
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4572-80.
2009: Xiuling Chi; Brittany Morgan Freeman; Min Tong; Yuhua Zhao; Hsin-Hsiung Tai
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells.
Archives of biochemistry and biophysics 2009;487(2):139-45.
2009: Min Yan; Seung-Jae Myung; Stephen P Fink; Earl Lawrence; James Lutterbaugh; Peiying Yang; Xiaohua Zhou; Danielle Liu; Ronald M Rerko; Joseph Willis; Dawn Dawson; Hsin-Hsiung Tai; Jill S Barnholtz-Sloan; Robert A Newman; Monica M Bertagnolli; Sanford D Markowitz
15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(23):9409-13.
2009: Wenchao Yang; Yongmei Pan; Fang Zheng; Hoon Cho; Hsin-Hsiung Tai; Chang-Guo Zhan
Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase.
Biophysical journal 2009;96(5):1931-8.
2008: Fang Zheng; Wenchao Yang; Mei-Chuan Ko; Junjun Liu; Hoon Cho; Daquan Gao; Min Tong; Hsin-Hsiung Tai; James H Woods; Chang-Guo Zhan
Most efficient cocaine hydrolase designed by virtual screening of transition states.
Journal of the American Chemical Society 2008;130(36):12148-55.
2008: Duncan Hughes; Taisuke Otani; Peiying Yang; Robert A Newman; Rhonda K Yantiss; Nasser K Altorki; Jeff L Port; Min Yan; Sanford D Markowitz; Madhu Mazumdar; Hsin-Hsiung Tai; Kotha Subbaramaiah; Andrew J Dannenberg
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.
Cancer prevention research (Philadelphia, Pa.) 2008;1(4):241-9.
2008: Naoki Wakimoto; Ido Wolf; Dong Yin; James O'Kelly; Tadayuki Akagi; Lilach Abramovitz; Keith L Black; Hsin-Hsiung Tai; H Phillip Koeffler
Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase.
Cancer research 2008;68(17):6978-86.
2008: Hung Pham; Guido Eibl; Romina Vincenti; Benny Chong; Hsin-Hsiung Tai; Lee W Slice
15-Hydroxyprostaglandin dehydrogenase suppresses K-RasV12-dependent tumor formation in Nu/Nu mice.
Molecular carcinogenesis 2008;47(6):466-77.
2008: Jeffrey D Roizen; Minoru Asada; Min Tong; Hsin-Hsiung Tai; Louis J Muglia
Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.
Molecular endocrinology (Baltimore, Md.) 2008;22(1):105-12.
2007: Xiuling Li; Jingyan Wei; Hsin-Hsiung Tai
Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells.
Archives of biochemistry and biophysics 2007;467(1):20-30.
2007: Jingyan Wei; Weili Yan; Xiuling Li; Wen-Chang Chang; Hsin-Hsiung Tai
Activation of thromboxane receptor alpha induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells.
Biochemical pharmacology 2007;74(5):787-800.
2007: Li Yang; Joseph M Amann; Takefumi Kikuchi; Rut Porta; Marta Guix; Adriana Gonzalez; Kyung-Ho Park; Dean Billheimer; Carlos L Arteaga; Hsin-Hsiung Tai; Raymond DuBois; David P Carbone; David H Johnson
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.
Cancer research 2007;67(12):5587-93.
2007: Hsin-Hsiung Tai; Min Tong; Yunfei Ding
15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer.
Prostaglandins & other lipid mediators 2007;83(3):203-8.
2007: Rose M Rizek; Carole S Watson; Sarah Keating; Hsin-Hsiung Tai; John R G Challis; Alan D Bocking
15-Hydroxyprostaglandin dehydrogenase protein expression in human fetal membranes with and without subclinical inflammation.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(3):260-9.
2007: Huiyong Yin; Ling Gao; Hsin-Hsiung Tai; Laine J Murphey; Ned A Porter; Jason D Morrow
Urinary prostaglandin F2alpha is generated from the isoprostane pathway and not the cyclooxygenase in humans.
The Journal of biological chemistry 2007;282(1):329-36.
2006: Min Tong; Yunfei Ding; Hsin-Hsiung Tai
Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells.
Carcinogenesis 2006;27(11):2170-9.
2006: Hoon Cho; Lingyu Huang; Adel Hamza; Daquan Gao; Chang-Guo Zhan; Hsin-Hsiung Tai
Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.
Bioorganic & medicinal chemistry 2006;14(19):6486-91.
2006: Min Tong; Yunfei Ding; Hsin-Hsiung Tai
Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells.
Biochemical pharmacology 2006;72(6):701-9.
2006: Ido Wolf; James O'Kelly; Tami Rubinek; Min Tong; Anh Nguyen; Bryan T Lin; Hsin-Hsiung Tai; Beth Y Karlan; H Phillip Koeffler
15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer.
Cancer research 2006;66(15):7818-23.
2006: Xiaoqin Huang; Weili Yan; Daquan Gao; Min Tong; Hsin-Hsiung Tai; Chang-Guo Zhan
Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis.
Bioorganic & medicinal chemistry 2006;14(10):3553-62.
2006: Weili Yan; Hsin-Hsiung Tai
Glycogen synthase kinase-3 phosphorylation, T-cell factor signaling activation, and cell morphology change following stimulation of thromboxane receptor alpha.
The Journal of pharmacology and experimental therapeutics 2006;317(1):267-74.
2006: Weili Yan; Yunfei Ding; Hsin-Hsiung Tai
14-3-3zeta interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase.
Biochemical pharmacology 2006;71(5):624-33.
2006: Taisuke Otani; Kentaro Yamaguchi; Ellen Scherl; Baoheng Du; Hsin-Hsiung Tai; Melanie Greifer; Lydia Petrovic; Takiko Daikoku; Sudhansu K Dey; Kotha Subbaramaiah; Andrew J Dannenberg
Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(2):G361-8.
2006: Daquan Gao; Hoon Cho; Wenchao Yang; Yongmei Pan; Guangfu Yang; Hsin-Hsiung Tai; Chang-Guo Zhan
Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation.
Angewandte Chemie (International ed. in English) 2006;45(4):653-7.
2006: Hsin-Hsiung Tai; Hoon Cho; Min Tong; Yunfei Ding
NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions.
Current pharmaceutical design 2006;12(8):955-62.
2005: Yongmei Pan; Daquan Gao; Wenchao Yang; Hoon Cho; Guangfu Yang; Hsin-Hsiung Tai; Chang-Guo Zhan
Computational redesign of human butyrylcholinesterase for anticocaine medication.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16656-61.
2005: Adel Hamza; Hoon Cho; Hsin-Hsiung Tai; Chang-Guo Zhan
Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation.
Bioorganic & medicinal chemistry 2005;13(14):4544-51.
2005: Adel Hamza; Hoon Cho; Hsin-Hsiung Tai; Chang-Guo Zhan
Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants.
The journal of physical chemistry. B 2005;109(10):4776-82.
2005: Min Tong; Hsin-Hsiung Tai
15-Hydroxyprostaglandin dehydrogenase can be induced by dexamethasone and other glucocorticoids at the therapeutic level in A549 human lung adenocarcinoma cells.
Archives of biochemistry and biophysics 2005;435(1):50-5.
2005: Michael G Backlund; Jason R Mann; Vijaykumar R Holla; F Gregory Buchanan; Hsin-Hsiung Tai; Erik S Musiek; Ginger L Milne; Sharada Katkuri; Raymond DuBois
15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer.
The Journal of biological chemistry 2005;280(5):3217-23.
2005: Hoon Cho; Adel Hamza; Chang-Guo Zhan; Hsin-Hsiung Tai
Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.
Archives of biochemistry and biophysics 2005;433(2):447-53.
2005: Yunfei Ding; Min Tong; Shuqian Liu; Jeffrey A Moscow; Hsin-Hsiung Tai
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer.
Carcinogenesis 2005;26(1):65-72.
2004: Min Yan; Ronald M Rerko; Petra Platzer; Dawn Dawson; Joseph Willis; Min Tong; Earl Lawrence; James Lutterbaugh; Shi-Long Lu; James Willson; Guangbin Luo; Jack O Hensold; Hsin-Hsiung Tai; Keith Wilson; Sanford D Markowitz
15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(50):17468-73.
2004: Shuqian Liu; Arnold Stromberg; Hsin-Hsiung Tai; Jeffrey A Moscow
Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells.
Molecular cancer research : MCR 2004;2(8):477-87.
2004: Min Tong; Hsin-Hsiung Tai
Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells.
Endocrinology 2004;145(5):2141-7.
2003: Hoon Cho; marcos oliveira; Hsin-Hsiung Tai
Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.
Archives of biochemistry and biophysics 2003;419(2):139-46.
2003: Ling Gao; William E Zackert; Justin J Hasford; Michael E Danekis; Ginger L Milne; Catha Remmert; Jeff Reese; Huiyong Yin; Hsin-Hsiung Tai; Sudhansu K Dey; Ned A Porter; Jason D Morrow
Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase.
The Journal of biological chemistry 2003;278(31):28479-89.
2002: Hoon Cho; Hsin-Hsiung Tai
Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents.
Prostaglandins, leukotrienes, and essential fatty acids 2002;67(6):461-5.
2002: Feng-Xiang Yan; Shuichi Yamamoto; Hui-Ping Zhou; Hsin-Hsiung Tai; Duan-Fang Liao
Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha.
Acta pharmacologica Sinica 2002;23(10):952-60.
2002: Hoon Cho; Hsin-Hsiung Tai
Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.
Archives of biochemistry and biophysics 2002;405(2):247-51.
2002: Hsin-Hsiung Tai; C Mark Ensor; Min Tong; Huiping Zhou; Fengxiang Yan
Prostaglandin catabolizing enzymes.
Prostaglandins & other lipid mediators 2002;68-69():483-93.
2002: Shuichi Yamamoto; Fengxiang Yan; Huiping Zhou; Hsin-Hsiung Tai
Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha.
Biochemical pharmacology 2002;64(3):375-83.
2002: Sandra K Winchester; Takuji Imamura; Gilad A Gross; Lisa M Muglia; Sherri K Vogt; Jason Wright; Kikuko Watanabe; Hsin-Hsiung Tai; Louis J Muglia
Coordinate regulation of prostaglandin metabolism for induction of parturition in mice.
Endocrinology 2002;143(7):2593-8.
2002: Hoon Cho; Hsin-Hsiung Tai
Threonine 11 of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase may interact with NAD(+) during catalysis.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(5-6):505-9.
2002: Hsin-Hsiung Tai; C Mark Ensor; Huiping Zhou; Fengxiang Yan
Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase.
Advances in experimental medicine and biology 2002;507():245-50.
2001: Kevin R Kozak; Brenda C Crews; Jennifer Panizzi; Hsin-Hsiung Tai; Jason D Morrow; Lawrence J Marnett
Metabolism of prostaglandin glycerol esters and prostaglandin ethanolamides in vitro and in vivo.
The Journal of biological chemistry 2001;276(40):36993-8.
2001: Shuichi Yamamoto; Fengxiang Yan; Huiping Zhou; Hsin-Hsiung Tai
Serine 331 is the major site of receptor phosphorylation induced by agents that activate protein kinase G in HEK 293 cells overexpressing thromboxane receptor alpha.
Archives of biochemistry and biophysics 2001;393(1):97-105.
2001: Huiping Zhou; Fengxiang Yan; Hsin-Hsiung Tai
Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases.
The Journal of pharmacology and experimental therapeutics 2001;298(3):1243-51.
2001: Huiping Zhou; Fengxiang Yan; Hsin-Hsiung Tai
C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates.
European journal of biochemistry / FEBS 2001;268(12):3368-74.
2000: Min Tong; Hsin-Hsiung Tai
Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells.
Biochemical and biophysical research communications 2000;276(1):77-81.
2000: Clary B Clish; Bruce D Levy; Nan Chiang; Hsin-Hsiung Tai; Charles N Serhan
Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation.
The Journal of biological chemistry 2000;275(33):25372-80.
2000: Min Tong; Hsin-Hsiung Tai
Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells.
Biochimica et biophysica acta 2000;1497(1):61-8.
2000: Huiping Zhou; Hsin-Hsiung Tai
Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding.
Archives of biochemistry and biophysics 2000;373(1):211-7.
1999: Huiping Zhou; Fengxiang Yan; Shuichi Yamamoto; Hsin-Hsiung Tai
Phenylalanine 138 in the second intracellular loop of human thromboxane receptor is critical for receptor-G-protein coupling.
Biochemical and biophysical research communications 1999;264(1):171-5.
1999: Huiping Zhou; Hsin-Hsiung Tai
Characterization of recombinant human CXCR4 in insect cells: role of extracellular domains and N-glycosylation in ligand binding.
Archives of biochemistry and biophysics 1999;369(2):267-76.
1999: M Wang; AK Bhattacharyya; MF Taylor; Hsin-Hsiung Tai; Delwood C Collins
Site-directed mutagenesis studies of the NADPH-binding domain of rat steroid 5alpha-reductase (isozyme-1) I: analysis of aromatic and hydroxylated amino acid residues.
Steroids 1999;64(5):356-62.
1999: Huiping Zhou; Hsin-Hsiung Tai
Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.
Biochemical and biophysical research communications 1999;257(2):414-7.
1999: Z Wang; Hsin-Hsiung Tai
Cyclic AMP response element mediates dexamethasone induced suppression of prostaglandin H synthase-2 gene expression in human amnion derived WISH cells.
Prostaglandins, leukotrienes, and essential fatty acids 1999;60(4):243-8.
1998: Nan Chiang; Tomoko Takano; Clary B Clish; Nicos A Petasis; Hsin-Hsiung Tai; Charles N Serhan
Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.
The Journal of pharmacology and experimental therapeutics 1998;287(2):779-90.
1998: C Huang; Hsin-Hsiung Tai
Prostaglandin E2 receptor EP3alpha subtype: the role of N-glycosylation in ligand binding as revealed by site-directed mutagenesis.
Prostaglandins, leukotrienes, and essential fatty acids 1998;59(4):265-71.
1998: Z Wang; Hsin-Hsiung Tai
Interleukin-1 beta and dexamethasone regulate gene expression of prostaglandin H synthase-2 via the NF-kB pathway in human amnion derived WISH cells.
Prostaglandins, leukotrienes, and essential fatty acids 1998;59(1):63-9.
1998: Nan Chiang; Hsin-Hsiung Tai
The role of N-glycosylation of human thromboxane A2 receptor in ligand binding.
Archives of biochemistry and biophysics 1998;352(2):207-13.
1998: C Mark Ensor; H Zhang; Hsin-Hsiung Tai
Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung.
The Biochemical journal 1998;330 ( Pt 1)():103-8.
1997: M Matsuo; C Mark Ensor; Hsin-Hsiung Tai
Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene.
Biochemical and biophysical research communications 1997;235(3):582-6.
1997: MF Taylor; M Wang; AK Bhattacharyya; Nan Chiang; Hsin-Hsiung Tai; Delwood C Collins
Expression of rat steroid 5 alpha-reductase (isozyme-1) in Spodoptera frugiperda, SF21, insect cells: expression of rat steroid 5 alpha-reductase.
Steroids 1997;62(4):373-8.
1997: H Zhang; M Matsuo; Huiping Zhou; C Mark Ensor; Hsin-Hsiung Tai
Cloning and expression of the cDNA for rat NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.
Gene 1997;188(1):41-4.
1997: Hsin-Hsiung Tai; C Huang; Nan Chiang
Structure and function of prostanoid receptors as revealed by site-directed mutagenesis.
Advances in experimental medicine and biology 1997;407():205-9.
1997: C Mark Ensor; Hsin-Hsiung Tai
Photoaffinity labeling of NAD(+)-linked enzymes.
Methods in enzymology 1997;280():204-10.
1997: CQ Vu; DL Coyle; Hsin-Hsiung Tai; Elaine L Jacobson; Myron K Jacobson
Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress.
Advances in experimental medicine and biology 1997;419():381-8.
1996: M Matsuo; C Mark Ensor; Hsin-Hsiung Tai
Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
Biochimica et biophysica acta 1996;1309(1-2):21-4.
1996: Nan Chiang; W M Kan; Hsin-Hsiung Tai
Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells.
Archives of biochemistry and biophysics 1996;334(1):9-17.
1996: C Mark Ensor; Hsin-Hsiung Tai
Cysteine 182 is essential for enzymatic activity of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
Archives of biochemistry and biophysics 1996;333(1):117-20.
1996: P Chen; Z Tian; G A Digenis; Hsin-Hsiung Tai
Enzyme immunoassay of two nicergoline metabolites, 10 alpha-methoxy-9, 10-dihydrolysergol (MDL) and 1-methyl-10 alpha-methoxy-9, 10-dihydrolysergol (MMDL).
Research communications in molecular pathology and pharmacology 1996;92(3):315-28.
1996: C Mark Ensor; Hsin-Hsiung Tai
Site-directed mutagenesis of the conserved serine 138 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase to an alanine results in an inactive enzyme.
Biochemical and biophysical research communications 1996;220(2):330-3.
1996: C Huang; Hsin-Hsiung Tai
Ser-268 plays an important role in ligand binding of prostaglandin E2 receptor EP3alpha subtype.
Archives of biochemistry and biophysics 1996;327(1):161-6.
1996: L Harding; Z Wang; Hsin-Hsiung Tai
Stimulation of prostaglandin E2 synthesis by interleukin-1beta is amplified by interferons but inhibited by interleukin-4 in human amnion-derived WISH cells.
Biochimica et biophysica acta 1996;1310(1):48-52.
1995: C Mark Ensor; Hsin-Hsiung Tai
15-Hydroxyprostaglandin dehydrogenase.
Journal of lipid mediators and cell signalling 1995;12(2-3):313-9.
1995: L Creed Pettigrew; J J Meyer; S D Craddock; S M Butler; Hsin-Hsiung Tai; Robert A Yokel
Delayed elevation of platelet activating factor in ischemic hippocampus.
Brain research 1995;691(1-2):243-7.
1995: Z Xia; Hsin-Hsiung Tai
Bacterial expression of functional membrane-bound thromboxane synthase having intact sequence and truncated N-terminal hydrophobic segment.
Archives of biochemistry and biophysics 1995;321(2):531-4.
1995: P Chen; Hsin-Hsiung Tai
A sensitive enzyme immunoassay for cyclosporin A using antibodies generated against a novel hapten.
Research communications in molecular pathology and pharmacology 1995;88(3):317-26.
1995: C Huang; Hsin-Hsiung Tai
Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells.
The Biochemical journal 1995;307 ( Pt 2)():493-8.
1995: M W Wilson; L T Lay; Ching Kuang Chow; Hsin-Hsiung Tai; Larry W Robertson; Howard P Glauert
Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid.
Archives of toxicology 1995;69(7):491-7.
1994: P L Chen; C Mark Ensor; Hsin-Hsiung Tai
An 125I-labeled N6-substituted azido analog of NAD+ for the photoaffinity labeling of NAD(+)-linked enzymes.
Photochemistry and photobiology 1994;60(5):455-8.
1994: C Mark Ensor; Hsin-Hsiung Tai
Bacterial expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
Biochimica et biophysica acta 1994;1208(1):151-6.
1994: H C Tau; Hsin-Hsiung Tai
Intracellular translocation of rap 1-B G-protein induced by prostaglandin E1 is blocked by phorbol ester in human platelets.
Prostaglandins, leukotrienes, and essential fatty acids 1994;50(6):299-302.
1994: R K Sangha; J C Walton; C M Ensor; Hsin-Hsiung Tai; John R G Challis
Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor.
The Journal of clinical endocrinology and metabolism 1994;78(4):982-9.
1994: Rong-Fong Shen; L Zhang; S J Baek; Hsin-Hsiung Tai; K D Lee
The porcine thromboxane synthase-encoding cDNA: sequence, mRNA expression and enzyme production in Sf9 insect cells.
Gene 1994;140(2):261-5.
1994: S Stanley; T Wood; J P Goodman; P A Henry; William E Woods; S L Chang; Hsin-Hsiung Tai; D Watt; S Kwiatkowski; J W Blake
Immunoassay detection of drugs in racing horses: detection of ethacrynic acid and bumetanide in equine urine by ELISA.
Journal of analytical toxicology 1994;18(2):95-100.
1993: Z Xia; Rong-Fong Shen; S J Baek; Hsin-Hsiung Tai
Expression of two different forms of cDNA for thromboxane synthase in insect cells and site-directed mutagenesis of a critical cysteine residue.
The Biochemical journal 1993;295 ( Pt 2)():457-61.
1993: A J Chavan; C Mark Ensor; P Wu; BE Haley; Hsin-Hsiung Tai
Photoaffinity labeling of human placental NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase with [alpha-32P]2N3NAD+. Identification of a peptide in the adenine ring binding domain.
The Journal of biological chemistry 1993;268(22):16437-42.
1993: W M Kan; Hsin-Hsiung Tai
Characterization of (5Z)-7-[3-endo-[(4-iodophenylsulfonyl) amino] -bicyclo[2.2.1]hep-2-exo-yl]heptenoic acid (IS-145) as an antagonist for the study of thromboxane A2 receptor.
Prostaglandins, leukotrienes, and essential fatty acids 1993;48(6):439-45.
1993: J Yang; Z Gao; Hsin-Hsiung Tai
[Isolation and purification of a NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase from human placenta].
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao / [bian ji zhe, Hua xi yi ke da xue xue bao bian wei hui] 1993;24(2):187-90.
1993: W M Kan; Hsin-Hsiung Tai
Improved synthesis of (5Z)-7-(3-endo-[(benzenesulfonamido)-bicyclo[2.2.1]heptyl]hept-5-enoic acid (S-145) derivatives and their iodine-125-labeled radioligands for the study of thromboxane A2 receptor.
Chemistry and physics of lipids 1993;65(1):57-64.
1993: W M Kan; Hsin-Hsiung Tai
Monoclonal anti-idiotypic antibody to a potent thromboxane A2 receptor antagonist and its interaction with thromboxane A2 receptor.
The Journal of biological chemistry 1993;268(9):6364-70.
1992: T Ichimaru; Hsin-Hsiung Tai
Alteration of platelet activating factor (PAF) metabolism in rat pulmonary alveolar macrophages and plasma by cigarette smoking.
Prostaglandins, leukotrienes, and essential fatty acids 1992;47(2):123-8.
1992: C Mark Ensor; Hsin-Hsiung Tai
Expression of the cDNA for NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase as a catalytically active enzyme in Escherichia coli.
Prostaglandins, leukotrienes, and essential fatty acids 1992;46(3):219-22.
1992: C Wang; Hsin-Hsiung Tai
A sensitive and specific radioimmunoassay for platelet-activating factor.
Lipids 1992;27(3):206-8.
1992: P Y Cheung; J C Walton; Hsin-Hsiung Tai; Simon C Riley; John R G Challis
Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy.
Gynecologic and obstetric investigation 1992;33(3):142-6.
1991: S Stanley; A Jeganathan; T Wood; P Henry; S Turner; William E Woods; M Green; Hsin-Hsiung Tai; D Watt; J Blake
Morphine and etorphine: XIV. Detection by ELISA in equine urine.
Journal of analytical toxicology 1991;15(6):305-10.
1991: C Q Xun; Z G Tian; Hsin-Hsiung Tai
Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester.
The Biochemical journal 1991;279 ( Pt 2)():553-8.
1991: C J Wang; Hsin-Hsiung Tai
Monoclonal anti-idiotypic antibodies to platelet activating factor (PAF) and their interaction with PAF receptors.
The Journal of biological chemistry 1991;266(19):12372-8.
1991: C Q Xun; C Mark Ensor; Hsin-Hsiung Tai
Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells.
Biochemical and biophysical research communications 1991;177(3):1258-65.
1991: C Mark Ensor; Hsin-Hsiung Tai
Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme.
Biochemical and biophysical research communications 1991;176(2):840-5.
1990: P Y Cheung; J C Walton; Hsin-Hsiung Tai; Simon C Riley; John R G Challis
Immunocytochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, and placenta.
American journal of obstetrics and gynecology 1990;163(5 Pt 1):1445-9.
1990: P Wu; M Fritzo; Hsin-Hsiung Tai
Purification and characterization of an NAD(+)-dependent dehydrogenase that catalyzes the oxidation of thromboxane B2 at C-11 from porcine liver. Development and application of 11-dehydro-thromboxane B2 radioimmunoassay to enzyme assay.
Biochimica et biophysica acta 1990;1036(1):55-63.
1990: C Mark Ensor; J Y Yang; R T Okita; Hsin-Hsiung Tai
Cloning and sequence analysis of the cDNA for human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
The Journal of biological chemistry 1990;265(25):14888-91.
1990: C J Wang; Hsin-Hsiung Tai
A facile synthesis of an aldehydic analog of platelet activating factor and its use in the production of specific antibodies.
Chemistry and physics of lipids 1990;55(3):265-73.
1990: H Yamazaki; Hsin-Hsiung Tai
Phorbol ester induces inhibition of arachidonate incorporation into phospholipids in human neutrophils.
Prostaglandins, leukotrienes, and essential fatty acids 1990;40(1):51-5.
1990: H Tanizawa; Hsin-Hsiung Tai
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Prostaglandins, leukotrienes, and essential fatty acids 1990;40(1):45-9.
1990: L A Shook; Thomas H Pauly; S L Marple; S J Horstman; Hsin-Hsiung Tai; B D Bowdy; M N Gillespie
Group B streptococcus promotes oxygen radical-dependent thromboxane accumulation in young piglets.
Pediatric research 1990;27(4 Pt 1):349-52.
1990: C L Tai; O T Mak; T Arai; Hsin-Hsiung Tai
Monoclonal antibodies that inhibit the enzyme activity of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase.
The Biochemical journal 1990;267(1):75-8.
1990: Y Tonogai; Hsin-Hsiung Tai
Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay.
Prostaglandins, leukotrienes, and essential fatty acids 1990;39(2):125-9.
1990: Hsin-Hsiung Tai; W C Chang; Y Liu; S Fukuda
Alterations of arachidonate metabolism in cardiovascular system by cigarette smoking.
Advances in experimental medicine and biology 1990;273():211-24.
1989: H Tanizawa; Hsin-Hsiung Tai
Synergism between chemotactic peptide and platelet-activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Biochemical pharmacology 1989;38(15):2559-63.
1989: T J Weckman; C L Tai; William E Woods; Hsin-Hsiung Tai; J W Blake; Thomas Tobin
Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses.
American journal of veterinary research 1989;50(4):502-7.
1989: I Fuse; T Iwanaga; Hsin-Hsiung Tai
Phorbol ester, 1,2-diacylglycerol, and collagen induce inhibition of arachidonic acid incorporation into phospholipids in human platelets.
The Journal of biological chemistry 1989;264(7):3890-5.
1989: T Wood; C L Tai; D G Taylor; William E Woods; C J Wang; P K Houtz; Hsin-Hsiung Tai; T J Weckman; J M Yang; L Sturma
Immunoassay detection of drugs in racing horses. IX. Detection of detomidine in equine blood and urine by radioimmunoassay.
Research communications in chemical pathology and pharmacology 1989;63(2):263-79.
1989: P Houtz; Hsin-Hsiung Tai
Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():678-83.
1989: I Fuse; Hsin-Hsiung Tai
Regulation of arachidonate release by G-proteins and protein kinase C in human platelets.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():574-9.
1989: Thomas Tobin; S Kwiatkowski; D S Watt; Hsin-Hsiung Tai; C L Tai; William E Woods; J P Goodman; D G Taylor; T J Weckman; J M Yang
Immunoassay detection of drugs in racing horses. XI. ELISA and RIA detection of fentanyl, alfentanil, sufentanil and carfentanil in equine blood and urine.
Research communications in chemical pathology and pharmacology 1989;63(1):129-52.
1988: L Y Chau; Hsin-Hsiung Tai
Monoglyceride and diglyceride lipases from human platelet microsomes.
Biochimica et biophysica acta 1988;963(3):436-44.
1988: Thomas Tobin; D S Watt; S Kwiatkowski; Hsin-Hsiung Tai; J W Blake; J McDonald; C A Prange; S Wie
Non-isotopic immunoassay drug tests in racing horses: a review of their application to pre- and post-race testing, drug quantitation, and human drug testing.
Research communications in chemical pathology and pharmacology 1988;62(3):371-95.
1988: I Fuse; Hsin-Hsiung Tai
Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets?
Biochimica et biophysica acta 1988;972(1):54-9.
1988: S Kwiatkowski; L Sturma; M R Dai; Hsin-Hsiung Tai; D S Watt; C L Tai; William E Woods; T J Weckman; J M Yang; T Wood
Immunoassay detection of drugs in racing horses. VII. Detection of acepromazine in equine urine and blood by ELISA and PCFIA.
Research communications in chemical pathology and pharmacology 1988;61(3):391-412.
1988: William E Woods; C J Wang; P K Houtz; Hsin-Hsiung Tai; T Wood; T J Weckman; J M Yang; S L Chang; J W Blake; Thomas Tobin
Immunoassay detection of drugs in racing horses. VI. Detection of furosemide (Lasix) in equine blood by a one step ELISA and PCFIA.
Research communications in chemical pathology and pharmacology 1988;61(1):111-28.
1988: C L Tai; C Wang; T J Weckman; M A Popot; William E Woods; J M Yang; J Blake; Hsin-Hsiung Tai; Thomas Tobin
Radioimmunoassay for etorphine in horses with a 125I analog of etorphine.
American journal of veterinary research 1988;49(5):622-8.
1988: Thomas Tobin; Hsin-Hsiung Tai; C L Tai; P K Houtz; M R Dai; William E Woods; J M Yang; T J Weckman; S L Chang; J W Blake
Immunoassay detection of drugs in racing horses. IV. Detection of fentanyl and its congeners in equine blood and urine by a one step ELISA assay.
Research communications in chemical pathology and pharmacology 1988;60(1):97-115.
1988: W M Hou; Z L Zhang; Hsin-Hsiung Tai
Purification and characterization of phosphatidylinositol kinase from porcine liver microsomes.
Biochimica et biophysica acta 1988;959(1):67-75.
1987: Rong-Fong Shen; Hsin-Hsiung Tai
Immunological studies on thromboxane synthase.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17A():34-8.
1986: William E Woods; Hsin-Hsiung Tai; C Tai; T Weckman; T Wood; H Barios; J W Blake; Thomas Tobin
High-sensitivity radioimmunoassay screening method for fentanyl.
American journal of veterinary research 1986;47(10):2180-3.