Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Kazunari Taira

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Concepts & Ideas

Anatomy

Hela Cells

Phenomena

Physiology

Transfection

Living Beings

Hepatitis Delta Virus

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
46
Kawasaki, Hiroaki
45
Miyagishi, Makoto
45
Warashina, Masaki
41
Nishikawa, Shin-Ichi
38
Kuwabara, Tomoko
24
Wadhwa, Renu
21
Kaul, Sunil
20
Ohkawa, Jun
20
Suyama, Eigo
17
KUMAR, PARMOD
14
Takagi, Yasuomi
12
Nishikawa, Fumiko
11
Sawata, Shinya
10
Yoshinari, Koichi
9
Onuki, Reiko

Sign-in to see all Coauthors

Publications

TOP 3
Inoue Atsushi; Sawata Shinya Y; Taira Kazunari; Wadhwa Renu
Loss-of-function screening by randomized intracellular antibodies: identification of hnRNP-K as a potential target for metastasis.
Sano Masayuki; Taira Kazunari
Hammerhead ribozyme-based target discovery.
Matsumoto Sahohime; Miyagishi Makoto; Taira Kazunari
Genome-wide sreening by using small-interfering RNA expression libraries.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Kazunari Taira (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2007: Inoue Atsushi; Sawata Shinya Y; Taira Kazunari; Wadhwa Renu
Loss-of-function screening by randomized intracellular antibodies: identification of hnRNP-K as a potential target for metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8983-8.
2007: Sano Masayuki; Taira Kazunari
Hammerhead ribozyme-based target discovery.
Methods in molecular biology (Clifton, N.J.) 2007;360():143-53.
2007: Matsumoto Sahohime; Miyagishi Makoto; Taira Kazunari
Genome-wide sreening by using small-interfering RNA expression libraries.
Methods in molecular biology (Clifton, N.J.) 2007;360():131-42.
2007: Fujita Satoshi; Zhou Jing-Min; Taira Kazunari
Ribosome-inactivation display system.
Methods in molecular biology (Clifton, N.J.) 2007;352():221-36.
2006: Onuki Reiko; Suyama Eigo; Taira Kazunari
Retraction: Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries.
Nature biotechnology 2006;24(9):1170.
2006: Ikeda Yutaka; Taira Kazunari
Ligand-targeted delivery of therapeutic siRNA.
Pharmaceutical research 2006;23(8):1631-40.
2006: Taira Kazunari
Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase.
EMBO reports 2006;7(7):746.
2006: Ito Masanori; Miyagishi Makoto; Murata Chisato; Kawasaki Hiroaki; Baba Tadashi; Tachi Chikashi; Taira Kazunari
Down-regulation of endogenous Wt1 expression by Sry transgene in the murine embryonic mesonephros-derived M15 cell line.
The Journal of reproduction and development 2006;52(3):415-27.
2006: Kasim Vivi; Taira Kazunari; Miyagishi Makoto
Screening of siRNA target sequences by using fragmentized DNA.
The journal of gene medicine 2006;8(6):782-91.
2006: Tateishi Keisuke; Ohta Miki; Guleng Bayasi; Kanai Fumihiko; Tanaka Yasuo; Asaoka Yoshinari; Jazag Amarsanaa; Imamura Jun; Imamura Takaaki; Ijichi Hideaki; Ikenoue Tsuneo; Kawakami Takayuki; Fukushima Yasushi; Washida Miwa; Sata Masataka; Miyagishi Makoto; Taira Kazunari; Yoshida Haruhiko; Kawabe Takao; Omata Masao
TRAIL-induced cell death cooperates with IFN-gamma activation in the graft-versus-tumor effect against colon tumors.
International journal of cancer. Journal international du cancer 2006;118(9):2237-46.
2006: Sano Masayuki; Kato Yoshio; Taira Kazunari
Sequence-specific interference by small RNAs derived from adenovirus VAI RNA.
FEBS letters 2006;580(6):1553-64.
2006: Haruki Hirohito; Okuwaki Mitsuru; Miyagishi Makoto; Taira Kazunari; Nagata Kyosuke
Involvement of template-activating factor I/SET in transcription of adenovirus early genes as a positive-acting factor.
Journal of virology 2006;80(2):794-801.
2006: Inoue Atsushi; Sawata Shinya Y; Taira Kazunari
Molecular design and delivery of siRNA.
Journal of drug targeting 2006;14(7):448-55.
2006: Fukuda Yoko; Kawasaki Hiroaki; Taira Kazunari
Construction of microRNA-containing vectors for expression in mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2006;338():167-73.
2006: Matsumoto S; Akashi H; Taira K
Screening and determination of gene function using randomized ribozyme and siRNA libraries.
Handbook of experimental pharmacology 2006;(173):197-221.
2005: Akashi Hideo; Miyagishi Makoto; Yokota Takanori; Watanabe Tsunamasa; Hino Taro; Nishina Kazutaka; Kohara Michinori; Taira Kazunari
Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA.
Molecular bioSystems 2005;1(5-6):382-90.
2005: Ohta Miki; Tateishi Keisuke; Kanai Fumihiko; Watabe Hirotsugu; Kondo Shintaro; Guleng Bayasi; Tanaka Yasuo; Asaoka Yoshinari; Jazag Amarsanaa; Imamura Jun; Ijichi Hideaki; Ikenoue Tsuneo; Sata Masataka; Miyagishi Makoto; Taira Kazunari; Tada Minoru; Kawabe Takao; Omata Masao
p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells.
Cancer research 2005;65(23):10822-9.
2005: Saito Yuki; Yokota Takanori; Mitani Tasuku; Ito Kaoru; Anzai Masayuki; Miyagishi Makoto; Taira Kazunari; Mizusawa Hidehiro
Transgenic small interfering RNA halts amyotrophic lateral sclerosis in a mouse model.
The Journal of biological chemistry 2005;280(52):42826-30.
2005: Ito Masanori; Kawano Kenji; Miyagishi Makoto; Taira Kazunari
Genome-wide application of RNAi to the discovery of potential drug targets.
FEBS letters 2005;579(26):5988-95.
2005: Wadhwa Renu; Takano Syuichi; Kaur Kamaljit; Aida Satoshi; Yaguchi Tomoko; Kaul Zeenia; Hirano Takashi; Taira Kazunari; Kaul Sunil C
Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60.
The Biochemical journal 2005;391(Pt 2):185-90.
2005: Guleng Bayasi; Tateishi Keisuke; Kanai Fumihiko; Jazag Amarsanaa; Ohta Miki; Asaoka Yoshinari; Ijichi Hideaki; Tanaka Yasuo; Imamura Jun; Ikenoue Tsuneo; Fukushima Yasushi; Morikane Keita; Miyagishi Makoto; Taira Kazunari; Kawabe Takao; Omata Masao
Cancer-derived VEGF plays no role in malignant ascites formation in the mouse.
World journal of gastroenterology : WJG 2005;11(35):5455-9.
2005: Watanabe Tomoko; Onuki Reiko; Yamashita Shinji; Taira Kazunari; Sugiyama Yuichi
Construction of a functional transporter analysis system using MDR1 knockdown Caco-2 cells.
Pharmaceutical research 2005;22(8):1287-93.
2005: Guleng Bayasi; Tateishi Keisuke; Ohta Miki; Kanai Fumihiko; Jazag Amarsanaa; Ijichi Hideaki; Tanaka Yasuo; Washida Miwa; Morikane Keita; Fukushima Yasushi; Yamori Takao; Tsuruo Takashi; Kawabe Takao; Miyagishi Makoto; Taira Kazunari; Sata Masataka; Omata Masao
Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner.
Cancer research 2005;65(13):5864-71.
2005: Matsumoto Sahohime; Miyagishi Makoto; Akashi Hideo; Nagai Ryozo; Taira Kazunari
Analysis of double-stranded RNA-induced apoptosis pathways using interferon-response noninducible small interfering RNA expression vector library.
The Journal of biological chemistry 2005;280(27):25687-96.
2005: Sano Masayuki; Kato Yoshio; Taira Kazunari
Functional gene-discovery systems based on libraries of hammerhead and hairpin ribozymes and short hairpin RNAs.
Molecular bioSystems 2005;1(1):27-35.
2005: Akashi Hideo; Matsumoto Sahohime; Taira Kazunari
Gene discovery by ribozyme and siRNA libraries.
Nature reviews. Molecular cell biology 2005;6(5):413-22.
2005: Masuda Shigeo; Kumano Keiki; Shimizu Kiyoshi; Imai Yoichi; Kurokawa Mineo; Ogawa Seishi; Miyagishi Makoto; Taira Kazunari; Hirai Hisamaru; Chiba Shigeru
Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300.
Cancer science 2005;96(5):274-82.
2005: Kawasaki Hiroaki; Taira Kazunari
Transcriptional gene silencing by short interfering RNAs.
Current opinion in molecular therapeutics 2005;7(2):125-31.
2005: Arya Harinder; Kaul Zeenia; Wadhwa Renu; Taira Kazunari; Hirano Takashi; Kaul Sunil C
Quantum dots in bio-imaging: Revolution by the small.
Biochemical and biophysical research communications 2005;329(4):1173-7.
2005: Wadhwa Renu; Deocaris Custer C; Widodo Nashi; Taira Kazunari; Kaul Sunil C
Imminent approaches towards molecular interventions in ageing.
Mechanisms of ageing and development 2005;126(4):481-90.
2005: Kawasaki Hiroaki; Taira Kazunari; Morris Kevin V
siRNA induced transcriptional gene silencing in mammalian cells.
Cell cycle (Georgetown, Tex.) 2005;4(3):442-8.
2005: Fujita Satoshi; Taki Takashi; Taira Kazunari
Selection of an active enzyme by phage display on the basis of the enzyme's catalytic activity in vivo.
Chembiochem : a European journal of chemical biology 2005;6(2):315-21.
2005: Ikeda Yutaka; Kawahara Shun-ichi; Yoshinari Koichi; Fujita Satoshi; Taira Kazunari
Specific 3'-terminal modification of DNA with a novel nucleoside analogue that allows a covalent linkage of a nuclear localization signal and enhancement of DNA stability.
Chembiochem : a European journal of chemical biology 2005;6(2):297-303.
2005: Saitoh Tatsuya; Yamamoto Masahiro; Miyagishi Makoto; Taira Kazunari; Nakanishi Makoto; Fujita Takashi; Akira Shizuo; Yamamoto Naoki; Yamaoka Shoji
A20 is a negative regulator of IFN regulatory factor 3 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1507-12.
2005: Jazag Amarsanaa; Ijichi Hideaki; Kanai Fumihiko; Imamura Takaaki; Guleng Bayasi; Ohta Miki; Imamura Jun; Tanaka Yasuo; Tateishi Keisuke; Ikenoue Tsuneo; Kawakami Takayuki; Arakawa Yoshihiro; Miyagishi Makoto; Taira Kazunari; Kawabe Takao; Omata Masao
Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
Oncogene 2005;24(4):662-71.
2005: Futami Takashi; Miyagishi Makoto; Taira Kazunari
Identification of a network involved in thapsigargin-induced apoptosis using a library of small interfering RNA expression vectors.
The Journal of biological chemistry 2005;280(1):826-31.
2005: Fukuda Yoko; Kawasaki Hiroaki; Taira Kazunari
Exploration of human miRNA target genes in neuronal differentiation.
Nucleic acids symposium series (2004) 2005;(49):341-2.
2005: Miyagishi Makoto; Matsumoto Sahohime; Akashi Hideo; Kawasaki Hiroaki; Fukao Taro; Fukuda Yoko; Sano Masayuki; Kato Yoshio; Takagi Yasuomi; Tanaka Yoshiyuki; Warashina Masaki; Kuwabara Tomoko; Sawata Shinya Y; Ikeda Yutaka; Kawahara Shun-ichi; Sunil Kaul C; Wadhwa Renu; Taira Kazunari
Chemistry-based RNA technologies: demonstration of usefulness of libraries of ribozymes and short hairpin RNAs (shRNAs).
Nucleic acids symposium series (2004) 2005;(49):91-2.
2005: Kuwabara Tomoko; Hsieh Jenny; Nakashima Kinichi; Warashina Masaki; Taira Kazunari; Gage Fred H
The NRSE smRNA specifies the fate of adult hippocampal neural stem cells.
Nucleic acids symposium series (2004) 2005;(49):87-8.
2005: Tanaka Yoshiyuki; Yamaguchi Hiroshi; Oda Shuji; Kojima Chojiro; Ono Akira; Taira Kazunari; Kondo Yoshinori
NMR spectroscopic analyses of functional nucleic acids-metal interaction and their solution structure analyses.
Nucleic acids symposium series (2004) 2005;(49):51-2.
2005: Jazag Amarsanaa; Kanai Fumihiko; Ijichi Hideaki; Tateishi Keisuke; Ikenoue Tsuneo; Tanaka Yasuo; Ohta Miki; Imamura Jun; Guleng Bayasi; Asaoka Yoshinari; Kawabe Takao; Miyagishi Makoto; Taira Kazunari; Omata Masao
Single small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway components.
Nucleic acids research 2005;33(15):e131.
2005: Sano Masayuki; Kato Yoshio; Akashi Hideo; Miyagishi Makoto; Taira Kazunari
Novel methods for expressing RNA interference in human cells.
Methods in enzymology 2005;392():97-112.
2004: Suzumura Ken-ichi; Takagi Yasuomi; Orita Masaya; Taira Kazunari
NMR-based reappraisal of the coordination of a metal ion at the pro-Rp oxygen of the A9/G10.1 site in a hammerhead ribozyme.
Journal of the American Chemical Society 2004;126(47):15504-11.
2004: Wadhwa Renu; Yaguchi Tomoko; Kaur Kamaljit; Suyama Eigo; Kawasaki Hiroyuki; Taira Kazunari; Kaul Sunil C
Use of a randomized hybrid ribozyme library for identification of genes involved in muscle differentiation.
The Journal of biological chemistry 2004;279(49):51622-9.
2004: Takagi Yasuomi; Inoue Atsushi; Taira Kazunari
Analysis on a cooperative pathway involving multiple cations in hammerhead reactions.
Journal of the American Chemical Society 2004;126(40):12856-64.
2004: Warashina Masaki; Kuwabara Tomoko; Nakamatsu Yuka; Takagi Yasuomi; Kato Yoshio; Taira Kazunari
Analysis of the conserved P9-G10.1 metal-binding motif in hammerhead ribozymes with an extra nucleotide inserted between A9 and G10.1 residues.
Journal of the American Chemical Society 2004;126(39):12291-7.
2004: Wadhwa Renu; Kaul Sunil C; Miyagishi Makoto; Taira Kazunari
Know-how of RNA interference and its applications in research and therapy.
Mutation research 2004;567(1):71-84.
2004: Kawasaki Hiroaki; Taira Kazunari
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells.
Nature 2004;431(7005):211-7.
2004: Suyama Eigo; Wadhwa Renu; Kaur Kamaljit; Miyagishi Makoto; Kaul Sunil C; Kawasaki Hiroaki; Taira Kazunari
Identification of metastasis-related genes in a mouse model using a library of randomized ribozymes.
The Journal of biological chemistry 2004;279(37):38083-6.
2004: Shiota Maki; Sano Masayuki; Miyagishi Makoto; Taira Kazunari
Ribozymes: applications to functional analysis and gene discovery.
Journal of biochemistry 2004;136(2):133-47.
2004: Wadhwa Renu; Kaul Sunil C; Miyagishi Makoto; Taira Kazunari
Vectors for RNA interference.
Current opinion in molecular therapeutics 2004;6(4):367-72.
2004: Deocaris Custer C; Kaul Sunil C; Taira Kazunari; Wadhwa Renu
Emerging technologies: trendy RNA tools for aging research.
The journals of gerontology. Series A, Biological sciences and medical sciences 2004;59(8):771-83.
2004: Miyagishi Makoto; Sumimoto Hidetoshi; Miyoshi Hiroyuki; Kawakami Yutaka; Taira Kazunari
Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells.
The journal of gene medicine 2004;6(7):715-23.
2004: Li Yi; Yokota Takanori; Matsumura Ryusuke; Taira Kazunari; Mizusawa Hidehiro
Sequence-dependent and independent inhibition specific for mutant ataxin-3 by small interfering RNA.
Annals of neurology 2004;56(1):124-9.
2004: Soda Yasushi; Tani Kenzaburo; Bai Yuansong; Saiki Minoru; Chen Minghan; Izawa Kiyoko; Kobayashi Seiichiro; Takahashi Satoshi; Uchimaru Kaoru; Kuwabara Tomoko; Warashina Masaaki; Tanabe Tsuyoshi; Miyoshi Hiroyuki; Sugita Kanji; Nakazawa Shinpei; Tojo Arinobu; Taira Kazunari; Asano Shigetaka
A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood 2004;104(2):356-63.
2004: Sawata Shinya Y; Suyama Eigo; Taira Kazunari
A system based on specific protein-RNA interactions for analysis of target protein-protein interactions in vitro: successful selection of membrane-bound Bak-Bcl-xL proteins in vitro.
Protein engineering, design & selection : PEDS 2004;17(6):501-8.
2004: Ohta Atsushi; Inoue Atsushi; Taira Kazunari
[Basic research on and application of RNA interference]
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(6):827-31.
2004: Taki Masumi; Kato Yoshio; Miyagishi Makoto; Takagi Yasuomi; Taira Kazunari
Small-interfering-RNA expression in cells based on an efficiently constructed dumbbell-shaped DNA.
Angewandte Chemie (International ed. in English) 2004;43(24):3160-3.
2004: Hasan Md Kamrul; Yaguchi Tomoko; Minoda Yasumasu; Hirano Takashi; Taira Kazunari; Wadhwa Renu; Kaul Sunil C
Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control.
The Biochemical journal 2004;380(Pt 3):605-10.
2004: Miyagishi Makoto; Matsumoto Sahohime; Taira Kazunari
Generation of an shRNAi expression library against the whole human transcripts.
Virus research 2004;102(1):117-24.
2004: Imamura Takaaki; Kanai Fumihiko; Kawakami Takayuki; Amarsanaa Jazag; Ijichi Hideaki; Hoshida Yujin; Tanaka Yasuo; Ikenoue Tsuneo; Tateishi Keisuke; Kawabe Takao; Arakawa Yoshihiro; Miyagishi Makoto; Taira Kazunari; Yokosuka Osamu; Omata Masao
Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression.
Biochemical and biophysical research communications 2004;318(1):289-96.
2004: Wadhwa Renu; Takano Syuichi; Taira Kazunari; Kaul Sunil C
Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
The journal of gene medicine 2004;6(4):439-44.
2004: Kawasaki Hiroaki; Wadhwa Renu; Taira Kazunari
World of small RNAs: from ribozymes to siRNA and miRNA.
Differentiation; research in biological diversity 2004;72(2-3):58-64.
2004: Suyama Eigo; Wadhwa Renu; Kawasaki Hiroaki; Yaguchi Tomoko; Kaul Sunil C; Nakajima Motowo; Taira Kazunari
LIM kinase-2 targeting as a possible anti-metastasis therapy.
The journal of gene medicine 2004;6(3):357-63.
2004: Taki Masumi; Shiota Maki; Taira Kazunari
Transglutaminase-mediated N- and C-terminal fluorescein labeling of a protein can support the native activity of the modified protein.
Protein engineering, design & selection : PEDS 2004;17(2):119-26.
2004: Onuki Reiko; Bando Yoshio; Suyama Eigo; Katayama Taiichi; Kawasaki Hiroaki; Baba Tadashi; Tohyama Masaya; Taira Kazunari
An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease.
The EMBO journal 2004;23(4):959-68.
2004: Tanaka Yoshiyuki; Kasai Yasuhiro; Mochizuki Shunsuke; Wakisaka Akihiro; Morita Eugene H; Kojima Chojiro; Toyozawa Atsushi; Kondo Yoshinori; Taki Masumi; Takagi Yasuomi; Inoue Atsushi; Yamasaki Kazuhiko; Taira Kazunari
Nature of the chemical bond formed with the structural metal ion at the A9/G10.1 motif derived from hammerhead ribozymes.
Journal of the American Chemical Society 2004;126(3):744-52.
2004: Yokota Takanori; Miyagishi Makoto; Hino Taro; Matsumura Ryusuke; Tasinato Andrea; Urushitani Makoto; Rao Rammohan V; Takahashi Ryosuke; Bredesen Dale E; Taira Kazunari; Mizusawa Hidehiro;
siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme.
Biochemical and biophysical research communications 2004;314(1):283-91.
2004: Wadhwa R; Sugihara T; Taira K; Kaul S C
The ARF-p53 senescence pathway in mouse and human cells.
Histology and histopathology 2004;19(1):311-6.
2004: Kimura Hitomi; Kawasaki Hiroaki; Taira Kazunari
Mouse microRNA-23b regulates expression of Hes1 gene in P19 cells.
Nucleic acids symposium series (2004) 2004;(48):213-4.
2004: Kawasaki Hiroaki; Taira Kazunari
MicroRNA-196 inhibits HOXB8 expression in myeloid differentiation of HL60 cells.
Nucleic acids symposium series (2004) 2004;(48):211-2.
2004: Mikuma Toshiyasu; Kawasaki Hiroaki; Yamamoto Yasuhiko; Taira Kazunari
Overexpression of Dicer enhances RNAi-mediated gene silencing by short-hairpin RNAs (shRNAs) in human cells.
Nucleic acids symposium series (2004) 2004;(48):191-2.
2004: Suyama Eigo; Kawasaki Hiroaki; Wadhwa Renu; Taira Kazunari
Cell migration and metastasis as targets of small RNA-based molecular genetic analyses.
Journal of muscle research and cell motility 2004;25(4-5):303-8.
2004: Uddin M Khabir; Kato Yoshio; Takagi Yasuomi; Mikuma Toshiyasu; Taira Kazunari
Phosphorylation at 5' end of guanosine stretches inhibits dimerization of G-quadruplexes and formation of a G-quadruplex interferes with the enzymatic activities of DNA enzymes.
Nucleic acids research 2004;32(15):4618-29.
2004: Inoue Atsushi; Takagi Yasuomi; Taira Kazunari
Importance in catalysis of a magnesium ion with very low affinity for a hammerhead ribozyme.
Nucleic acids research 2004;32(14):4217-23.
2004: Kasim Vivi; Miyagishi Makoto; Taira Kazunari
Control of siRNA expression using the Cre-loxP recombination system.
Nucleic acids research 2004;32(7):e66.
2004: Akashi Hideo; Miyagishi Makoto; Taira Kazunari
RNAi expression vectors in plant cells.
Methods in molecular biology (Clifton, N.J.) 2004;252():533-43.
2004: Miyagishi Makoto; Taira Kazunari
RNAi expression vectors in mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2004;252():483-91.
2004: Iyo Mayu; Kawasaki Hiroaki; Taira Kazunari
Maxizyme technology.
Methods in molecular biology (Clifton, N.J.) 2004;252():257-65.
2004: Kato Yoshio; Tsunemi Masaru; Miyagishi Makoto; Kawasaki Hiroaki; Taira Kazunari
Functional gene discovery using hybrid ribozyme libraries.
Methods in molecular biology (Clifton, N.J.) 2004;252():245-56.
2004: Kawasaki Hiroaki; Warashina Masaki; Kuwabara Tomoko; Taira Kazunari
Helicase-attached novel hybrid ribozymes.
Methods in molecular biology (Clifton, N.J.) 2004;252():237-43.
2004: Sano Masayuki; Taira Kazunari
Ribozyme expression systems.
Methods in molecular biology (Clifton, N.J.) 2004;252():195-207.
2004: Yoshinari Koichi; Miyagishi Makoto; Taira Kazunari
Effects on RNAi of the tight structure, sequence and position of the targeted region.
Nucleic acids research 2004;32(2):691-9.
2003: Sawata Shinya Y; Taira Kazunari
Modified peptide selection in vitro by introduction of a protein-RNA interaction.
Protein engineering 2003;16(12):1115-24.
2003: Kaul Zeenia; Yaguchi Tomoko; Kaul Sunil C; Hirano Takashi; Wadhwa Renu; Taira Kazunari
Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates.
Cell research 2003;13(6):503-7.
2003: Oshima Keisuke; Kawasaki Hiroaki; Soda Yasushi; Tani Kenzaburo; Asano Shigetaka; Taira Kazunari
Maxizymes and small hairpin-type RNAs that are driven by a tRNA promoter specifically cleave a chimeric gene associated with leukemia in vitro and in vivo.
Cancer research 2003;63(20):6809-14.
2003: Nishiwaki Yasunobu; Yokota Takanori; Hiraoka Megumi; Miyagishi Makoto; Taira Kazunari; Isobe Mitsuaki; Mizusawa Hidehiro; Yoshida Masayuki
Introduction of short interfering RNA to silence endogenous E-selectin in vascular endothelium leads to successful inhibition of leukocyte adhesion.
Biochemical and biophysical research communications 2003;310(4):1062-6.
2003: Inoue Atsushi; Takagi Yasuomi; Taira Kazunari
Importance of magnesium ions in the mechanism of catalysis by a hammerhead ribozyme: strictly linear relationship between the ribozyme activity and the concentration of magnesium ions.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 2003;16(3):210-7.
2003: Ikeda Yutaka; Kawahara Shun-ichi; Taki Masumi; Kuno Atsushi; Hasegawa Tsunemi; Taira Kazunari
Synthesis of a novel histidine analogue and its efficient incorporation into a protein in vivo.
Protein engineering 2003;16(9):699-706.
2003: Onuki Reiko; Nagasaki Akira; Taira Kazunari
[Visualization of activated caspase 8 using fluorescent resonance energy transfer (FRET)]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(11 Suppl):1573-7.
2003: Fujita Satoshi; Sawata Shinya Y; Taira Kazunari
[In vitro selection for protein: linkage between genotype and phenotype]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(11 Suppl):1464-73.
2003: Minoshima Hiroshi; Suyama Eigo; Kawasaki Hiroaki; Taira Kazunari
[RNAi-mediated specific gene silencing and its application to medical treatments of viral infectious disease]
Uirusu. Journal of virology 2003;53(1):7-14.
2003: Kawasaki Hiroaki; Taira Kazunari
Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cells.
Nature 2003;423(6942):838-42.
2003: Yamauchi Toshimasa; Kamon Junji; Ito Yusuke; Tsuchida Atsushi; Yokomizo Takehiko; Kita Shunbun; Sugiyama Takuya; Miyagishi Makoto; Hara Kazuo; Tsunoda Masaki; Murakami Koji; Ohteki Toshiaki; Uchida Shoko; Takekawa Sato; Waki Hironori; Tsuno Nelson H; Shibata Yoichi; Terauchi Yasuo; Froguel Philippe; Tobe Kazuyuki; Koyasu Shigeo; Taira Kazunari; Kitamura Toshio; Shimizu Takao; Nagai Ryozo; Kadowaki Takashi
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.
Nature 2003;423(6941):762-9.
2003: Wadhwa Renu; Ando Hiroshi; Kawasaki Hiroaki; Taira Kazunari; Kaul Sunil C
Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes.
EMBO reports 2003;4(6):595-601.
2003: Yokota Takanori; Sakamoto Naoya; Enomoto Nobuyuki; Tanabe Yoko; Miyagishi Makoto; Maekawa Shinya; Yi Li; Kurosaki Masayuki; Taira Kazunari; Watanabe Mamoru; Mizusawa Hidehiro
Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs.
EMBO reports 2003;4(6):602-8.
2003: Kawahara Shun-ichi; Uchimaru Tadafumi; Taira Kazunari
2-Pyridone and 3-oxo-1,2,6-thiadiazine-1,1-dioxide derivatives: a new class of hydrogen bond equivalents of uracil.
Journal of computer-aided molecular design 2003;17(5-6):329-34.
2003: Kaul Sunil C; Yaguchi Tomoko; Taira Kazunari; Reddel Roger R; Wadhwa Renu
Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts.
Experimental cell research 2003;286(1):96-101.
2003: Suyama Eigo; Kawasaki Hiroaki; Nakajima Motowo; Taira Kazunari
Identification of genes involved in cell invasion by using a library of randomized hybrid ribozymes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5616-21.
2003: Onuki Reiko; Kawasaki Hiroaki; Baba Tadashi; Taira Kazunari
Analysis of a mitochondrial apoptotic pathway using Bid-targeted ribozymes in human MCF7 cells in the absence of a caspase-3-dependent pathway.
Antisense & nucleic acid drug development 2003;13(2):75-82.
2003: Suyama Eigo; Kawasaki Hiroaki; Onuki Reiko; Taira Kazunari
[Gene discovery system with randomized ribozyme libraries]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(4 Suppl):532-9.
2003: Wadhwa Renu; Yaguchi Tomoko; Hasan Md Kamrul; Taira Kazunari; Kaul Sunil C
Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation.
Biochemical and biophysical research communications 2003;302(4):735-42.
2003: Wadhwa Renu; Sugihara Takashi; Hasan Md Kamrul; Duncan Emma L; Taira Kazunari; Kaul Sunil C
A novel putative collaborator of p19ARF.
Experimental gerontology 2003;38(3):245-52.
2003: Futami Takashi; Miyagishi Makoto; Iwai Shigenori; Seki Minoru; Taira Kazunari
Stimulatory effect of an indirectly attached RNA helicase-recruiting sequence on the suppression of gene expression by antisense oligonucleotides.
Antisense & nucleic acid drug development 2003;13(1):9-17.
2003: Miyagishi Makoto; Hayashi Mariko; Taira Kazunari
Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells.
Antisense & nucleic acid drug development 2003;13(1):1-7.
2003: Kawasaki Hiroaki; Suyama Eigo; Iyo Mayu; Taira Kazunari
siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells.
Nucleic acids research 2003;31(3):981-7.
2003: Kawasaki Hiroaki; Taira Kazunari
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells.
Nucleic acids research 2003;31(2):700-7.
2003: Suyama Eigo; Kawasaki Hiroaki; Kasaoka Tatsuhiko; Taira Kazunari
Identification of genes responsible for cell migration by a library of randomized ribozymes.
Cancer research 2003;63(1):119-24.
2003: Kato Yoshio; Taira Kazunari
Expression of siRNA from a single transcript that includes multiple ribozymes in mammalian cells.
Oligonucleotides 2003;13(5):335-43.
2003: Miyagishi Makoto; Taira Kazunari
Strategies for generation of an siRNA expression library directed against the human genome.
Oligonucleotides 2003;13(5):325-33.
2003: Kawasaki Hiroaki; Kuwabara Tomoko; Miyagishi Makoto; Taira Kazunari
Identification of functional genes by libraries of ribozymes and siRNAs.
Nucleic acids research. Supplement (2001) 2003;(3):331-2.
2003: Kato Yoshio; Sano Masayuki; Taira Kazunari
Analysis of processing-defective variants of human tRNA(Val).
Nucleic acids research. Supplement (2001) 2003;(3):283-4.
2003: Kasim Vivi; Miyagishi Makoto; Taira Kazunari
Control of siRNA expression utilizing Cre-loxP recombination system.
Nucleic acids research. Supplement (2001) 2003;(3):255-6.
2003: Suyama Eigo; Kawasaki Hiroaki; Taira Kazunari
Use of a ribozyme library for validation of gene functions and cellular pathways.
Nucleic acids research. Supplement (2001) 2003;(3):253-4.
2003: Minoshima Hiroshi; Suyama Eigo; Kawasaki Hiroaki; Taira Kazunari
Cancer gene validation using ribozymes and macroarray.
Nucleic acids research. Supplement (2001) 2003;(3):251-2.
2003: Kawasaki Hiroaki; Taira Kazunari
Functional analysis of microRNAs during the retinoic acid-induced neuronal differentiation of human NT2 cells.
Nucleic acids research. Supplement (2001) 2003;(3):243-4.
2003: Taki Masumi; Kato Yoshio; Miyagishi Makoto; Takagi Yasuomi; Sano Masayuki; Taira Kazunari
A direct and efficient synthesis method for dumbell-shaped linear DNA using PCR in vitro.
Nucleic acids research. Supplement (2001) 2003;(3):191-2.
2003: Tanaka Yoshiyuki; Kasai Yasuhiro; Morita Eugene H; Kojima Chojiro; Toyozawa Atsushi; Yamasaki Kazuhiko; Taira Kazunari; Kondo Yoshinori
NMR spectroscopic investigations of the roles of the metal ion at A9/G10.1 site in hammerhead ribozymes.
Nucleic acids research. Supplement (2001) 2003;(3):45-6.
2002: Takagi Y; Suyama E; Kawasaki H; Miyagishi M; Taira K
Mechanism of action of hammerhead ribozymes and their applications in vivo: rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries.
Biochemical Society transactions 2002;30(Pt 6):1145-9.
2002: Onuki Reiko; Nagasaki Akira; Kawasaki Hiroaki; Baba Tadashi; Uyeda Taro Q P; Taira Kazunari
Confirmation by FRET in individual living cells of the absence of significant amyloid beta -mediated caspase 8 activation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14716-21.
2002: Sano Masayuki; Kuwabara Tomoko; Warashina Masaki; Fukamizu Akiyoshi; Taira Kazunari
Novel method for selection of tRNA-driven ribozymes with enhanced stability in mammalian cells.
Antisense & nucleic acid drug development 2002;12(5):341-52.
2002: Kaul Sunil C; Taira Kazunari; Pereira-Smith Olivia M; Wadhwa Renu
Mortalin: present and prospective.
Experimental gerontology 2002;37(10-11):1157-64.
2002: Hasan Md Kamrul; Yaguchi Tomoko; Sugihara Takashi; Kumar Penmetcha K R; Taira Kazunari; Reddel Roger R; Kaul Sunil C; Wadhwa Renu
CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53.
The Journal of biological chemistry 2002;277(40):37765-70.
2002: Suyama Eigo; Kawasaki Hiroaki; Taira Kazunari
Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-alpha-induced apoptosis.
FEBS letters 2002;528(1-3):63-9.
2002: Wadhwa Renu; Sugihara Takashi; Hasan Md Kamrul; Taira Kazunari; Reddel Roger R; Kaul Sunil C
A major functional difference between the mouse and human ARF tumor suppressor proteins.
The Journal of biological chemistry 2002;277(39):36665-70.
2002: Kawasaki Hiroaki; Taira Kazunari
A functional gene discovery in the Fas-mediated pathway to apoptosis by analysis of transiently expressed randomized hybrid-ribozyme libraries.
Nucleic acids research 2002;30(16):3609-14.
2002: Wadhwa Renu; Colgin Lorel; Yaguchi Tomoko; Taira Kazunari; Reddel Roger R; Kaul Sunil C
Rhodacyanine dye MKT-077 inhibits in vitro telomerase assay but has no detectable effects on telomerase activity in vivo.
Cancer research 2002;62(15):4434-8.
2002: Suzumura Ken-ichi; Yoshinari Koichi; Tanaka Yoshiyuki; Takagi Yasuomi; Kasai Yasuhiro; Warashina Masaki; Kuwabara Tomoko; Orita Masaya; Taira Kazunari
A reappraisal, based on (31)P NMR, of the direct coordination of a metal ion with the phosphoryl oxygen at the cleavage site of a hammerhead ribozyme.
Journal of the American Chemical Society 2002;124(28):8230-6.
2002: Kuwabara Tomoko; Warashina Masaki; Taira Kazunari
Cleavage of an inaccessible site by the maxizyme with two independent binding arms: an alternative approach to the recruitment of RNA helicases.
Journal of biochemistry 2002;132(1):149-55.
2002: Kasai Yasuhiro; Shizuku Hideki; Takagi Yasuomi; Warashina Masaki; Taira Kazunari
Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity.
Nucleic acids research 2002;30(11):2383-9.
2002: Zhou Jing-Min; Zhou De-Min; Takagi Yasuomi; Kasai Yasuhiro; Inoue Atsushi; Baba Tadashi; Taira Kazunari
Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme.
Nucleic acids research 2002;30(11):2374-82.
2002: Akashi Hideo; Kawasaki Hiroaki; Kim Won Jong; Akaike Toshihiro; Taira Kazunari; Maruyama Atsushi
Enhancement in the cleavage activity of a hammerhead ribozyme by cationic comb-type polymers and an RNA helicase in vitro.
Journal of biochemistry 2002;131(5):687-92.
2002: Miyagishi Makoto; Taira Kazunari
U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.
Nature biotechnology 2002;20(5):497-500.
2002: Tanaka Yoshiyuki; Kojima Chojiro; Morita Eugene H; Kasai Yasuhiro; Yamasaki Kazuhiko; Ono Akira; Kainosho Masatsune; Taira Kazunari
Identification of the metal ion binding site on an RNA motif from hammerhead ribozymes using (15)N NMR spectroscopy.
Journal of the American Chemical Society 2002;124(17):4595-601.
2002: Kawasaki Hiroaki; Taira Kazunari
Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase.
EMBO reports 2002;3(5):443-50.
2002: Iyo Mayu; Kawasaki Hiroaki; Taira Kazunari
Allosterically controllable maxizymes for molecular gene therapy.
Current opinion in molecular therapeutics 2002;4(2):154-65.
2002: Takagi Yasuomi; Taira Kazunari
Detection of a proton-transfer process by kinetic solvent isotope effects in NH(4)(+)-mediated reactions catalyzed by a hammerhead ribozyme.
Journal of the American Chemical Society 2002;124(15):3850-2.
2002: Fujita Satoshi; Sawata Shinya Y; Yamamoto-Fujita Rika; Endo Yaeta; Kise Hideo; Iwakura Masahiro; Taira Kazunari
Novel approach for linking genotype to phenotype in vitro by exploiting an extremely strong interaction between RNA and protein.
Journal of medicinal chemistry 2002;45(8):1598-606.
2002: Kawasaki Hiroaki; Onuki Reiko; Suyama Eigo; Taira Kazunari
Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries.
Nature biotechnology 2002;20(4):376-80.
2002: He Qiu-Chen; Zhou Jing-Min; Zhou De-Min; Nakamatsu Yuka; Baba Tadashi; Taira Kazunari
Comparison of metal-ion-dependent cleavages of RNA by a DNA enzyme and a hammerhead ribozyme.
Biomacromolecules 2002;3(1):69-83.
2002: Zhou Jing-Min; Fujita Satoshi; Warashina Masaki; Baba Tadashi; Taira Kazunari
A novel strategy by the action of ricin that connects phenotype and genotype without loss of the diversity of libraries.
Journal of the American Chemical Society 2002;124(4):538-43.
2002: Kawasaki Hiroaki; Tsunemi Masaru; Iyo Mayu; Oshima Keisuke; Minoshima Hiroshi; Hamada Akira; Onuki Reiko; Suyama Eigo; Taira Kazunari
A functional gene discovery in cell differentiation by hybrid ribozyme and siRNA libraries.
Nucleic acids research. Supplement (2001) 2002;(2):275-6.
2002: Takagi Yasuomi; Taira Kazunari
Analyses of kinetic solvent isotope effects of a hammerhead ribozyme reaction in NH4+ and Li+ ions.
Nucleic acids research. Supplement (2001) 2002;(2):273-4.
2002: Futami Takashi; Miyagishi Makoto; Seki Minoru; Taira Kazunari
Induction of apoptosis in HeLa cells with siRNA expression vector targeted against bcl-2.
Nucleic acids research. Supplement (2001) 2002;(2):251-2.
2002: Suyama Eigo; Minoshima Hiroshi; Kawasaki Hiroaki; Taira Kazunari
Identification of AP-2-regulated genes by macroarray profiling of gene expression in human A375P melanoma.
Nucleic acids research. Supplement (2001) 2002;(2):247-8.
2002: Kawahara Shun-ichi; Sekine Mitsuo; Taira Kazunari; Kobayashi Hideyuki; Uchimaru Tadafumi
Theoretical study of substitution effect of the hydrogen bond stability of 9-methylguanine derivatives and 1-methylcytosine.
Nucleic acids research. Supplement (2001) 2002;(2):191-2.
2002: Iyo Mayu; Kawasaki Hiroaki; Taira Kazunari
Construction of an allosteric trans-maxizyme targeting for two distinct oncogenes.
Nucleic acids research. Supplement (2001) 2002;(2):115-6.
2002: Miyagishi Makoto; Taira Kazunari
Development and application of siRNA expression vector.
Nucleic acids research. Supplement (2001) 2002;(2):113-4.
2002: Ikeda Yutaka; Taira Kazunari
Biologically important reactions catalyzed by RNA molecules.
Chemical record (New York, N.Y.) 2002;2(5):307-18.
2001: Akashi H; Miyagishi M; Taira K
Suppression of gene expression by RNA interference in cultured plant cells.
Antisense & nucleic acid drug development 2001;11(6):359-67.
2001: Miyagishi M; Kuwabara T; Taira K
Transport of intracellularly active ribozymes to the cytoplasm.
Cancer chemotherapy and pharmacology 2001;48 Suppl 1():S96-101.
2001: Kuwabara T; Warashina M; Koseki S; Sano M; Ohkawa J; Nakayama K; Taira K
Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells.
Nucleic acids research 2001;29(13):2780-8.
2001: Warashina M; Kuwabara T; Kato Y; Sano M; Taira K
RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5572-7.
2001: Takagi Y; Warashina M; Stec W J; Yoshinari K; Taira K
Recent advances in the elucidation of the mechanisms of action of ribozymes.
Nucleic acids research 2001;29(9):1815-34.
2001: Kato Y; Kuwabara T; Warashina M; Toda H; Taira K
Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells.
The Journal of biological chemistry 2001;276(18):15378-85.
2001: Fujii R; Okamoto M; Aratani S; Oishi T; Ohshima T; Taira K; Baba M; Fukamizu A; Nakajima T
A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1.
The Journal of biological chemistry 2001;276(8):5445-51.
2001: Taki M; Sawata S Y; Taira K
Specific N-terminal biotinylation of a protein in vitro by a chemically modified tRNA(fmet) can support the native activity of the translated protein.
Journal of bioscience and bioengineering 2001;92(2):149-53.
2001: Zhou J M; Fujita S; Warashina M; Sawata S Y; Baba T; Taira K
A novel approach to selection of functional proteins.
Nucleic acids research. Supplement (2001) 2001;(1):253-4.
2001: Akashi H; Miyagishi M; Kurata H; Nagata T; Taira K
A simple and rapid system for the quantitation of RNA interference in plant cultured cells.
Nucleic acids research. Supplement (2001) 2001;(1):235-6.
2001: Suyama E; Kawasaki H; Taira K
Characterization of pro-apoptotic gene Bak using hammerhead ribozymes.
Nucleic acids research. Supplement (2001) 2001;(1):207-8.
2001: Taki M; Sawata S Y; Taira K
A novel immobilization method of an active protein via in vitro N-terminal specific incorporation system of nonnatural amino acids.
Nucleic acids research. Supplement (2001) 2001;(1):197-8.
2001: Kawasaki H; Taira K
Discovery of functional genes in the post-genome era by novel RNA-protein hybrid ribozymes.
Nucleic acids research. Supplement (2001) 2001;(1):133-4.
2001: Sawata S Y; Taira K
Development of an advanced polysome display system dependent on a specific protein-RNA motif interaction.
Nucleic acids research. Supplement (2001) 2001;(1):99-100.
2001: Nakayama A; Kawasaki H; Jin C; Munekata E; Taira K; Yokoyama K K
Transcriptional regulation of interferon gamma gene by p300 co-activator.
Nucleic acids research. Supplement (2001) 2001;(1):89-90.
2001: Kasai Y; Tanaka Y; Morita E H; Tanaka Y; Taira K
Physicochemical analysis of the interaction between a metal ion and the metal-ion-binding motif in hammerhead ribozymes.
Nucleic acids research. Supplement (2001) 2001;(1):81-2.
2001: Onuki R; Kawasaki H; Baba T; Taira K
Use of Bid-ribozymes to characterize and Bid-affiliated apoptotic pathway.
Nucleic acids research. Supplement (2001) 2001;(1):63-4.
2001: Kawahara S; Kobori A; Taira K; Sekine M; Uchimaru T
Ab initio molecular orbital evaluation of the hydrogen bond energy of base pairs formed between substituted 1-methylcytosine derivatives and 9-methylguanine.
Nucleic acids research. Supplement (2001) 2001;(1):29-30.
2001: Kuwabara T; Warashina M; Sano M; Tang H; Wong-Staal F; Munekata E; Taira K
Recognition of engineered tRNAs with an extended 3' end by Exportin-t (Xpo-t) and transport of tRNA-attached ribozymes to the cytoplasm in somatic cells.
Biomacromolecules 2001;2(4):1229-42.
2001: Kuwabara T; Tanabe T; Warashina M; Xiong K X; Tani K; Taira K; Asano S
Allosterically controllable maxizyme-mediated suppression of progression of leukemia in mice.
Biomacromolecules 2001;2(4):1220-8.
2001: Kuwabara T; Hamada M; Warashina M; Taira K
Allosterically controlled single-chained maxizymes with extremely high and specific activity.
Biomacromolecules 2001;2(3):788-99.
2000: Hwang J; Fauzi H; Fukuda K; Sekiya S; Kakiuchi N; Shimotohno K; Taira K; Kusakabe I; Nishikawa S
The RNA aptamer-binding site of hepatitis C virus NS3 protease.
Biochemical and biophysical research communications 2000;279(2):557-62.
2000: Kuwabara T; Warashina M; Taira K
Allosterically controllable ribozymes with biosensor functions.
Current opinion in chemical biology 2000;4(6):669-77.
2000: Warashina M; Kuwabara T; Taira K
Working at the cutting edge: the creation of allosteric ribozymes.
Structure (London, England : 1993) 2000;8(11):R207-12.
2000: Kuwabara T; Warashina M; Taira K
Allosterically controllable maxizymes cleave mRNA with high efficiency and specificity.
Trends in biotechnology 2000;18(11):462-8.
2000: Warashina M; Takagi Y; Stec W J; Taira K
Differences among mechanisms of ribozyme-catalyzed reactions.
Current opinion in biotechnology 2000;11(4):354-62.
2000: Tanabe T; Kuwabara T; Warashina M; Tani K; Taira K; Asano S
Oncogene inactivation in a mouse model.
Nature 2000;406(6795):473-4.
2000: Nakamatsu Y; Warashina M; Kuwabara T; Tanaka Y; Yoshinari K; Taira K
Significant activity of a modified ribozyme with N7-deazaguanine at g10.1: the double-metal-ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(8):603-12.
2000: Fukuda K; Vishnuvardhan D; Sekiya S; Hwang J; Kakiuchi N; Taira K; Shimotohno K; Kumar P K; Nishikawa S
Isolation and characterization of RNA aptamers specific for the hepatitis C virus nonstructural protein 3 protease.
European journal of biochemistry / FEBS 2000;267(12):3685-94.
2000: Yamamoto R; Katahira M; Nishikawa S; Baba T; Taira K; Kumar P K
A novel RNA motif that binds efficiently and specifically to the Ttat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(5):371-88.
2000: Suzumura K; Warashina M; Yoshinari K; Tanaka Y; Kuwabara T; Orita M; Taira K
Significant change in the structure of a ribozyme upon introduction of a phosphorothioate linkage at P9: NMR reveals a conformational fluctuation in the core region of a hammerhead ribozyme.
FEBS letters 2000;473(1):106-12.
2000: Yoshinari K; Taira K
A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme.
Nucleic acids research 2000;28(8):1730-42.
2000: Zhou J M; Nakamatsu Y; Kuwabara T; Warashina M; Tanaka Y; Yoshinari K; Taira K
Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizyme.
Journal of inorganic biochemistry 2000;78(4):261-8.
2000: Ohkawa J; Taira K
Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoter.
Human gene therapy 2000;11(4):577-85.
2000: Oda M; Kobayashi N; Ito A; Kurusu Y; Taira K
cis-acting regulatory sequences for antitermination in the transcript of the Bacillus subtilis hut operon and histidine-dependent binding of HutP to the transcript containing the regulatory sequences.
Molecular microbiology 2000;35(5):1244-54.
2000: Nakayama A; Warashina M; Kuwabara T; Taira K
Effects of cetyltrimethylammonium bromide on reactions catalyzed by maxizymes, a novel class of metalloenzymes.
Journal of inorganic biochemistry 2000;78(1):69-77.
2000: Kato Y; Kuwabara T; Toda H; Warashina M; Taira K
Suppression of BCR-ABL mRNA by various ribozymes in HeLa cells.
Nucleic acids symposium series 2000;(44):283-4.
2000: Hwang J; Fauzi H; Fukuda K; Sekiya S; Kakiuchi N; Taira K; Kusakabe I; Nishikawa S
Analysis of aptamer binding site for HCV-NS3 protease by alanine scanning mutagenesis.
Nucleic acids symposium series 2000;(44):253-4.
2000: Sano M; Kuwabara T; Nara Y; Warashina M; Taira K
Construction of a ribozyme-expression system that effectively transports ribozymes to the cytoplasm.
Nucleic acids symposium series 2000;(44):203-4.
2000: Takeda H; Kawasaki H; Taira K
Functional analysis of the pro-apoptotic factor Bax using hammerhead ribozymes.
Nucleic acids symposium series 2000;(44):169-70.
2000: Sekiya S; Fukuda K; Hwang J; Kakiuchi N; Taira K; Kusakabe I; Nishikawa S
Analysis of interaction between RNA aptamer and protein using nucleotide analogs.
Nucleic acids symposium series 2000;(44):163-4.
2000: Tanabe T; Takata I; Kuwabara T; Warashina M; Kawasaki H; Tani K; Ohta S; Asano S; Taira K
Maxizymes, novel allosterically controllable ribozymes, can be designed to cleave various substrates.
Biomacromolecules 2000;1(1):108-17.
1999: Hamada M; Kuwabara T; Warashina M; Nakayama A; Taira K
Specificity of novel allosterically trans- and cis-activated connected maxizymes that are designed to suppress BCR-ABL expression.
FEBS letters 1999;461(1-2):77-85.
1999: Kuno A; Shimizu D; Kaneko S; Hasegawa T; Gama Y; Hayashi K; Kusakabe I; Taira K
Significant enhancement in the binding of p-nitrophenyl-beta-D-xylobioside by the E128H mutant F/10 xylanase from Streptomyces olivaceoviridis E-86.
FEBS letters 1999;450(3):299-305.
1999: Nakayama A; Kuwabara T; Warashina M; Taira K
CTAB-mediated enrichment for active forms of novel dimeric maxizymes.
FEBS letters 1999;448(1):67-74.
1999: Warashina M; Kuwabara T; Nakamatsu Y; Taira K
Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosome.
Chemistry & biology 1999;6(4):237-50.
1999: Kuwabara T; Warashina M; Nakayama A; Ohkawa J; Taira K
tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: simultaneous cleavage at two sites in HIV-1 Tat mRNA in cultured cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):1886-91.
1999: Koseki S; Tanabe T; Tani K; Asano S; Shioda T; Nagai Y; Shimada T; Ohkawa J; Taira K
Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III.
Journal of virology 1999;73(3):1868-77.
1999: Nakamatsu Y; Warashina M; Kuwabara T; Tanaka Y; Shibata A; Yoshinari K; Taira K
Action of metal ions directly involved in the cleavage reaction of hammerhead ribozymes.
Nucleic acids symposium series 1999;(42):283-4.
1999: Zhou J M; Nakamatsu Y; Kuwabara T; Warashina M; Tanaka Y; Yoshinari K; Taira K
Probing of the secondary structure of maxizymes.
Nucleic acids symposium series 1999;(42):219-20.
1998: Kuwabara T; Warashina M; Tanabe T; Tani K; Asano S; Taira K
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivo.
Molecular cell 1998;2(5):617-27.
1998: Kuwabara T; Warashina M; Orita M; Koseki S; Ohkawa J; Taira K
Formation of a catalytically active dimer by tRNA(Val)-driven short ribozymes.
Nature biotechnology 1998;16(10):961-5.
1998: Zhou D M; He Q C; Zhou J M; Taira K
Explanation by a putative triester-like mechanism for the thio effects and Mn2+ rescues in reactions catalyzed by a hammerhead ribozyme.
FEBS letters 1998;431(2):154-60.
1998: Ota N; Warashina M; Hirano K; Hatanaka K; Taira K
Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity.
Nucleic acids research 1998;26(14):3385-91.
1998: Koseki S; Ohkawa J; Yamamoto R; Takebe Y; Taira K
A simple assay system for examination of the inhibitory potential in vivo of decoy RNAs, ribozymes and other drugs by measuring the Tat-mediated transcription of a fusion gene composed of the long terminal repeat of HIV-1 and a gene for luciferase.
Journal of controlled release : official journal of the Controlled Release Society 1998;53(1-3):159-73.
1998: Hamada M; Fujita S; Kise H; Jigami Y; Taira K
Comparison of in vivo activities of 5'-connected and 3'-connected cis-acting ribozymes: selection of intracellularly active ribozymes using the gene for dihydrofolate reductase (DHFR) as a selective marker in Escherichia coli.
Journal of biochemistry 1998;123(4):684-92.
1998: Ota N; Hirano K; Warashina M; Andrus A; Mullah B; Hatanaka K; Taira K
Determination of interactions between structured nucleic acids by fluorescence resonance energy transfer (FRET): selection of target sites for functional nucleic acids.
Nucleic acids research 1998;26(3):735-43.
1997: Zhou D M; Zhang L H; Taira K
Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion effects on the cleavage rates of 5'-oxy and 5'-thio substrates by a hammerhead ribozyme.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14343-8.
1997: Kumar P K; Machida K; Urvil P T; Kakiuchi N; Vishnuvardhan D; Shimotohno K; Taira K; Nishikawa S
Isolation of RNA aptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA.
Virology 1997;237(2):270-82.
1997: Yamamoto R; Koseki S; Ohkawa J; Murakami K; Nishikawa S; Taira K; Kumar P K
Inhibition of transcription by the TAR RNA of HIV-1 in a nuclear extract of HeLa cells.
Nucleic acids research 1997;25(17):3445-50.
1997: Kuwabara T; Warashina M; Tanabe T; Tani K; Asano S; Taira K
Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA.
Nucleic acids research 1997;25(15):3074-81.
1997: Fujita S; Koguma T; Ohkawa J; Mori K; Kohda T; Kise H; Nishikawa S; Iwakura M; Taira K
Discrimination of a single base change in a ribozyme using the gene for dihydrofolate reductase as a selective marker in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):391-6.
1997: Kuwabara T; Warashina M; Nakayama A; Ohkawa J; Taira K
Activities of tRNA-embedded dimeric minizymes.
Nucleic acids symposium series 1997;(37):307-8.
1997: Warashina M; Kuwabara T; Taira K
Comparison of activities between hammerhead ribozymes and DNA enzymes targeted to L6 BCR-ABL chimeric (b2a2) mRNA.
Nucleic acids symposium series 1997;(37):213-4.
1997: Ota N; Hirano K; Warashina M; Andrus A; Mullah B; Hatanaka K; Taira K
Structural analysis of nucleic acids by using fluorescence resonance energy transfer (FRET).
Nucleic acids symposium series 1997;(37):207-8.
1996: Hirano K; Uchiyama H; Taira K
[Detection of undegraded oligonucleotides in living cells by fluorescence resonance energy transfer]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(14):2139-43.
1996: Kawakami J; Yuda K; Suh Y A; Kumar P K; Nishikawa F; Maeda H; Taira K; Ohtsuka E; Nishikawa S
Constructing an efficient trans-acting genomic HDV ribozyme.
FEBS letters 1996;394(2):132-6.
1996: Kawasaki H; Ohkawa J; Tanishige N; Yoshinari K; Murata T; Yokoyama K K; Taira K
Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase.
Nucleic acids research 1996;24(15):3010-6.
1996: Kuwabara T; Amontov S V; Warashina M; Ohkawa J; Taira K
Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes.
Nucleic acids research 1996;24(12):2302-10.
1996: Amontov S; Nishikawa S; Taira K
Dependence on Mg2+ ions of the activities of dimeric hammerhead minizymes.
FEBS letters 1996;386(2-3):99-102.
1996: Orita M; Vinayak R; Andrus A; Warashina M; Chiba A; Kaniwa H; Nishikawa F; Nishikawa S; Taira K
Magnesium-mediated conversion of an inactive form of a hammerhead ribozyme to an active complex with its substrate. An investigation by NMR spectroscopy.
The Journal of biological chemistry 1996;271(16):9447-54.
1996: Uchiyama H; Hirano K; Kashiwasake-Jibu M; Taira K
Detection of undegraded oligonucleotides in vivo by fluorescence resonance energy transfer. Nuclease activities in living sea urchin eggs.
The Journal of biological chemistry 1996;271(1):380-4.
1995: Ohkawa J; Koguma T; Kohda T; Taira K
Ribozymes: from mechanistic studies to applications in vivo.
Journal of biochemistry 1995;118(2):251-8.
1995: Shimayama T; Nishikawa S; Taira K
Extraordinary enhancement of the cleavage activity of a DNA-armed hammerhead ribozyme at elevated concentrations of Mg2+ ions.
FEBS letters 1995;368(2):304-6.
1995: Ohkawa J; Taira K
[Inhibition of HIV replication by ribozyme strategy]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(10):1421-9.
1995: Taira K
[The chemistry of phosphorus: pseudorotation]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(10):1323-32.
1995: Shimayama T; Nishikawa S; Taira K
Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes.
Biochemistry 1995;34(11):3649-54.
1995: Takagi Y; Taira K
Temperature-dependent change in the rate-determining step in a reaction catalyzed by a hammerhead ribozyme.
FEBS letters 1995;361(2-3):273-6.
1995: Koguma T; Ohkawa J; Mori K; Fujita S; Nishikawa S; Iwakura M; Taira K
A novel screening system for construction and selection of active ribozymes using DHFR (dihydrofolate reductase) gene as selection marker.
Nucleic acids symposium series 1995;(34):221-2.
1995: Orita M; Vinayak R; Andrus A; Takagi Y; Chiba A; Kaniwa H; Nishikawa F; Nishikawa S; Taira K
Magnesium is essential for formation of an active complex of a hammerhead ribozyme with its substrate: an investigation by NMR spectroscopy.
Nucleic acids symposium series 1995;(34):219-20.
1995: Yamamoto R; Toyoda S; Viljanen P; Machida K; Nishikawa S; Murakami K; Taira K; Kumar P K
In vitro selection of RNA aptamers that can bind specifically to Tat protein of HIV-1.
Nucleic acids symposium series 1995;(34):145-6.
1995: Nishikawa F; Chiba A; Shirai M; Fauzi H; Taira K; Kumar P K; Nishikawa S
In vitro selection analysis of trans-acting HDV ribozyme.
Nucleic acids symposium series 1995;(34):115-6.
1995: Uchiyama H; Hirano K; Kashiwasake-Jibu M; Mullah B; Andrus A; Taira K
Detection of undegraded oligonucleotides in living sea urchin eggs by fluorescence resonance energy transfer.
Nucleic acids symposium series 1995;(34):111-2.
1994: Yuyama N; Ohkawa J; Koguma T; Shirai M; Taira K
A multifunctional expression vector for an anti-HIV-1 ribozyme that produces a 5'- and 3'-trimmed trans-acting ribozyme, targeted against HIV-1 RNA, and cis-acting ribozymes that are designed to bind to and thereby sequester trans-activator proteins such as Tat and Rev.
Nucleic acids research 1994;22(23):5060-7.
1994: Jeoung Y H; Kumar P K; Suh Y A; Taira K; Nishikawa S
Identification of phosphate oxygens that are important for self-cleavage activity of the HDV ribozyme by phosphorothioate substitution interference analysis.
Nucleic acids research 1994;22(18):3722-7.
1994: Inokuchi Y; Yuyama N; Hirashima A; Nishikawa S; Ohkawa J; Taira K
A hammerhead ribozyme inhibits the proliferation of an RNA coliphage SP in Escherichia coli.
The Journal of biological chemistry 1994;269(15):11361-6.
1994: Kumar P K; Taira K; Nishikawa S
Chemical probing studies of variants of the genomic hepatitis delta virus ribozyme by primer extension analysis.
Biochemistry 1994;33(2):583-92.
1993: Orita M; Nishikawa F; Shimayama T; Taira K; Endo Y; Nishikawa S
High-resolution NMR study of a synthetic oligoribonucleotide with a tetranucleotide GAGA loop that is a substrate for the cytotoxic protein, ricin.
Nucleic acids research 1993;21(24):5670-8.
1993: Ohkawa J; Yuyama N; Takebe Y; Nishikawa S; Taira K
Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11302-6.
1993: Sawata S; Shimayama T; Komiyama M; Kumar P K; Nishikawa S; Taira K
Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions.
Nucleic acids research 1993;21(24):5656-60.
1993: Kawakami J; Kumar P K; Suh Y A; Nishikawa F; Kawakami K; Taira K; Ohtsuka E; Nishikawa S
Identification of important bases in a single-stranded region (SSrC) of the hepatitis delta (delta) virus ribozyme.
European journal of biochemistry / FEBS 1993;217(1):29-36.
1993: Suh Y A; Kumar P K; Taira K; Nishikawa S
Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions.
Nucleic acids research 1993;21(14):3277-80.
1993: Suh Y A; Kumar P K; Kawakami J; Nishikawa F; Taira K; Nishikawa S
Systematic substitution of individual bases in two important single-stranded regions of the HDV ribozyme for evaluation of the role of specific bases.
FEBS letters 1993;326(1-3):158-62.
1993: Shimayama T; Nishikawa F; Nishikawa S; Taira K
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages.
Nucleic acids research 1993;21(11):2605-11.
1993: Uchimaru T; Uebayasi M; Tanabe K; Taira K
Theoretical analyses on the role of Mg2+ ions in ribozyme reactions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(1):137-42.
1993: Kumar P K; Suh Y A; Taira K; Nishikawa S
Point and compensation mutations to evaluate essential stem structures of genomic HDV ribozyme.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(1):124-9.
1993: Uchimaru T; Tanabe K; Shimayama T; Uebayasi M; Taira K
Theoretical analyses on the role of metal cations in RNA cleavage processes.
Nucleic acids symposium series 1993;(29):179-80.
1993: Shimayama T; Nishikawa S; Taira K
Cleavage of the highly conserved hairpin-loop region of HIV-1 by synthetic ribozymes.
Nucleic acids symposium series 1993;(29):177-8.
1993: Ohkawa J; Yuyama N; Takebe Y; Nisikawa S; Homann M; Sczakiel G; Taira K
Multiple site-specific cleavage of HIV RNA by transcribed ribozymes from shotgun-type trimming plasmid.
Nucleic acids symposium series 1993;(29):121-2.
1993: Nishikawa S; Kumar P K; Jeoung Y H; Kawakami J; Nishikawa F; Suh Y; Ohtsuka E; Taira K
Chemical probing studies of the hepatitis delta virus (HDV) genomic ribozyme.
Nucleic acids symposium series 1993;(29):119-20.
1992: Uchimaru T; Storer J W; Tanabe K; Uebayasi M; Nishikawa S; Taira K
RNA hydrolysis via an oxyphosphorane intermediate.
Biochemical and biophysical research communications 1992;187(3):1523-8.
1992: Yuyama N; Ohkawa J; Inokuchi Y; Shirai M; Sato A; Nishikawa S; Taira K
Construction of a tRNA-embedded-ribozyme trimming plasmid.
Biochemical and biophysical research communications 1992;186(3):1271-9.
1992: Kumar P K; Suh Y A; Miyashiro H; Nishikawa F; Kawakami J; Taira K; Nishikawa S
Random mutations to evaluate the role of bases at two important single-stranded regions of genomic HDV ribozyme.
Nucleic acids research 1992;20(15):3919-24.
1992: Suh Y A; Kumar P K; Nishikawa F; Kayano E; Nakai S; Odai O; Uesugi S; Taira K; Nishikawa S
Deletion of internal sequence on the HDV-ribozyme: elucidation of functionally important single-stranded loop regions.
Nucleic acids research 1992;20(4):747-53.
1992: Yliniemela A; Uchimaru T; Tanabe K; Uebayasi M; Taira K
Pentacoordinate oxyphosphorane intermediate always exists in aqueous solution.
Nucleic acids symposium series 1992;(27):57-8.
1992: Nishikawa S; Suh Y A; Kumar P K; Kawakami J; Nishikawa F; Taira K
Identification of important bases for the self-cleavage activity at two single-stranded regions of genomic HDV ribozyme.
Nucleic acids symposium series 1992;(27):41-2.
1992: Ohkawa J; Yuyama N; Taira K
Activities of HIV-RNA targeted ribozymes transcribed from a 'shot-gun' type ribozyme-trimming plasmid.
Nucleic acids symposium series 1992;(27):15-6.
1991: Taira K; Nakagawa K; Nishikawa S; Furukawa K
Construction of a novel RNA-transcript-trimming plasmid which can be used both in vitro in place of run-off and (G)-free transcriptions and in vivo as multi-sequences transcription vectors.
Nucleic acids research 1991;19(19):5125-30.
1991: Taira K; Uchimaru T; Tanabe K; Uebayasi M; Nishikawa S
Rate limiting P-O(5') bond cleavage of RNA fragment: ab initio molecular orbital calculations on the base-catalyzed hydrolysis of phosphate.
Nucleic acids research 1991;19(10):2747-53.
1991: Furukawa K; Nakagawa K; Yuyama N; Sato A; Kokean Y; Kato H; Yamashita S; Hayase N; Nishikawa S; Taira K
Highly conserved coding sequences in polychlorinated biphenyl (PCB)-degraders of Pseudomonas pseudoalcaligenes KF707 and Pseudomonas putida KF715.
Nucleic acids symposium series 1991;(25):115-6.
1991: Uebayasi M; Uchimaru T; Tanabe K; Nishikawa S; Taira K
Preferential chelation of cationic ligands to axial-equatorial oxygens over equatorial-equatorial dianionic oxygens: implication to the mechanism of action of ribozymes.
Nucleic acids symposium series 1991;(25):107-8.
1990: Taira K; Oda M; Shinshi H; Maeda H; Furukawa K
Construction of a novel artificial-ribozyme-releasing plasmid.
Protein engineering 1990;3(8):733-7.
1990: Taira K; Uebayasi M; Maeda H; Furukawa K
Energetics of RNA cleavage: implications for the mechanism of action of ribozymes.
Protein engineering 1990;3(8):691-701.
1990: Hayase N; Taira K; Furukawa K
Pseudomonas putida KF715 bphABCD operon encoding biphenyl and polychlorinated biphenyl degradation: cloning, analysis, and expression in soil bacteria.
Journal of bacteriology 1990;172(2):1160-4.
1990: Ohme-Takagi M; Shinshi H; Oda M; Uchimaru T; Nishikawa S; Taira K
In vivo RNA transcript-releasing plasmid possessing a universal pseudo-terminator by means of artificial ribozymes.
Nucleic acids symposium series 1990;(22):49-50.
1990: Uchimaru T; Tanabe K; Ucbayasi M; Nishikawa S; Taira K
Ab initio investigations on the intermediates of RNA cleaving processes.
Nucleic acids symposium series 1990;(22):47-8.
1989: Furukawa K; Hayase N; Taira K; Tomizuka N
Molecular relationship of chromosomal genes encoding biphenyl/polychlorinated biphenyl catabolism: some soil bacteria possess a highly conserved bph operon.
Journal of bacteriology 1989;171(10):5467-72.
1989: Uchimaru T; Tsuzuki S; Tanabe K; Benkovic S J; Furukawa K; Taira K
Computational studies on pterins and speculations on the mechanism of action of dihydrofolate reductase.
Biochemical and biophysical research communications 1989;161(1):64-8.
1989: Taira K; Uebayasi M; Furukawa K
Cyclic oxyphosphoranes as model intermediates during splicing and cleavage of RNA: ab initio molecular orbital calculations on the conformational analysis.
Nucleic acids research 1989;17(10):3699-708.

Sign-in to see more