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Yoshikazu Takada

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Masaaki Fujita; Yoko K Takada; Yoshikazu Takada
Insulin-like growth factor (IGF) signaling requires αvβ3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activation.
Long Ye; Yoko K Takada; Tiffany Dickerson; Masaaki Fujita; Handeep Kaur; John M Knapp; Mark J Kurth; Kit S Lam; Ruiwu Liu; Neil E Schore; Yoshikazu Takada
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.
Masaaki Fujita; Yoko K Takada; Yoshikazu Takada
Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1.

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2013: Masaaki Fujita; Yoko K Takada; Yoshikazu Takada
Insulin-like growth factor (IGF) signaling requires αvβ3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activation.
The Journal of biological chemistry 2013;288(5):3059-69.
2013: Long Ye; Yoko K Takada; Tiffany Dickerson; Masaaki Fujita; Handeep Kaur; John M Knapp; Mark J Kurth; Kit S Lam; Ruiwu Liu; Neil E Schore; Yoshikazu Takada
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.
Bioorganic & medicinal chemistry letters 2013;23(1):340-5.
2012: Masaaki Fujita; Yoko K Takada; Yoshikazu Takada
Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(12):5809-19.
2012: Takayuki Uematsu; Motoharu Seiki; Yoshikazu Takada; Taizo Tomari; Nagayasu Egawa; Xiao Han; Daisuke Hoshino; Toshiaki Isobe; Chieko Konishi; Naohiko Koshikawa
Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT-1080 cells.
Journal of cellular physiology 2012;227(8):3072-9.
2012: Masaaki Fujita; Katsuaki Ieguchi; Kiyotoshi Sekiguchi; Yoko K Takada; Yukimasa Taniguchi; Satoshi Yamaji; Parastoo Davari; Yoshikazu Takada
Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions.
The Journal of biological chemistry 2012;287(15):12491-500.
2012: Joy X Jiang; Fu-Tong Liu; Fiona Scott; Nobuko Serizawa; Yoshikazu Takada; Yoko Takada; Roger Adamson; Kornelia Baghy; Jenny Chen; Xiangling Chen; Sridevi Devaraj; Hiroo Fukada; Daniel K Hsu; Natalie J Török
Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(4):G439-46.
2012: Yoshikazu Takada
Potential role of kringle-integrin interaction in plasmin and uPA actions (a hypothesis).
Journal of biomedicine & biotechnology 2012;2012():136302.
2012: Yi-Ping Shih; Yoshikazu Takada; Su Hao Lo
Silencing of DLC1 upregulates PAI-1 expression and reduces migration in normal prostate cells.
Molecular cancer research : MCR 2012;10(1):34-9.
2011: Dominik R Haudenschild; Yoshikazu Takada; Matthias Mörgelin; Kaylene D Snow; Jasper Yik; Brett Chromy; Eunmee Hong; Chitrangada Acharya; Paul E Di Cesare
Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein.
The Journal of biological chemistry 2011;286(50):43250-8.
2011: Fiona E Fleming; Kate L Graham; Yoshikazu Takada; Barbara S Coulson
Determinants of the specificity of rotavirus interactions with the alpha2beta1 integrin.
The Journal of biological chemistry 2011;286(8):6165-74.
2010: Katsuaki Ieguchi; Masaaki Fujita; Zi Ma; Parastoo Davari; Yukimasa Taniguchi; Kiyotoshi Sekiguchi; Bobby Wang; Yoko K Takada; Yoshikazu Takada
Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling.
The Journal of biological chemistry 2010;285(41):31388-98.
2010: Wenwu Xiao; Yan Wang; Edmond Y Lau; Juntao Luo; Nianhuan Yao; Changying Shi; Leah Meza; Harry Tseng; Yoshiko Maeda; Pappanaicken Kumaresan; Ruiwu Liu; Felice C Lightstone; Yoshikazu Takada; Kit S Lam
The use of one-bead one-compound combinatorial library technology to discover high-affinity αvβ3 integrin and cancer targeting arginine-glycine-aspartic acid ligands with a built-in handle.
Molecular cancer therapeutics 2010;9(10):2714-23.
2010: Yoshikazu Takada; Yoko Ono; Jun Saegusa; Jun Sagusa; Constantine Mitsiades; Nicholas Mitsiades; Jean Tsai; Yong He; Ernest Maningding; Annie Coleman; Dalila Ramirez-Maverakis; Raphael Rodrigues; Raphael Rodriquez; Yoko Takada; Emanual Maverakis
A T cell-binding fragment of fibrinogen can prevent autoimmunity.
Journal of autoimmunity 2010;34(4):453-9.
2010: Satoshi Yamaji; Jun Saegusa; Katsuaki Ieguchi; Masaaki Fujita; Yoko K Takada; Seiji Mori; Yoshikazu Takada
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
PloS one 2010;5(4):e10273.
2009: Jun Saegusa; Satoshi Yamaji; Katsuaki Ieguchi; Chun-Yi Wu; Kit S Lam; Fu-Tong Liu; Yoko K Takada; Yoshikazu Takada
The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling.
The Journal of biological chemistry 2009;284(36):24106-14.
2009: Mingzhang Guo; Dayle A Daines; Jing Tang; Qiang Shen; Rachel M Perrin; Yoshikazu Takada; Sarah Y Yuan; Mack H Wu
Fibrinogen-gamma C-terminal fragments induce endothelial barrier dysfunction and microvascular leak via integrin-mediated and RhoA-dependent mechanism.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):394-400.
2009: Nianhuan Yao; Wenwu Xiao; Xiaobing Wang; Jan Marik; See-Hyoung Park; Yoshikazu Takada; Kit S Lam
Discovery of targeting ligands for breast cancer cells using the one-bead one-compound combinatorial method.
Journal of medicinal chemistry 2009;52(1):126-33.
2008: Jun Saegusa; Nobuaki Akakura; Chun-Yi Wu; Case Hoogland; Zi Ma; Kit S Lam; Fu-Tong Liu; Yoko K Takada; Yoshikazu Takada
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner.
The Journal of biological chemistry 2008;283(38):26107-15.
2008: Seiji Mori; Chun-Yi Wu; Satoshi Yamaji; Jun Saegusa; Biao Shi; Zi Ma; Yasuko Kuwabara; Kit S Lam; R Rivkah Isseroff; Yoko K Takada; Yoshikazu Takada
Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling.
The Journal of biological chemistry 2008;283(26):18066-75.
2008: Henri H Versteeg; Florence Schaffner; Marjolein Kerver; Helle H Petersen; Jasimuddin Ahamed; Brunhilde Felding-Habermann; Yoshikazu Takada; Barbara M Mueller; Wolfram Ruf
Inhibition of tissue factor signaling suppresses tumor growth.
Blood 2008;111(1):190-9.
2007: Yoshikazu Takada; Xiaojing Ye; Scott Simon
The integrins.
Genome biology 2007;8(5):215.
2007: Fiona E Fleming; Kate L Graham; K Taniguchi; Yoshikazu Takada; Barbara S Coulson
Rotavirus-neutralizing antibodies inhibit virus binding to integrins alpha 2 beta 1 and alpha 4 beta 1.
Archives of virology 2007;152(6):1087-101.
2006: Nobuaki Akakura; Case Hoogland; Yoko K Takada; Jun Saegusa; Xiaojing Ye; Fu-Tong Liu; Anthony Tze-Wai Cheung; Yoshikazu Takada
The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth.
Cancer research 2006;66(19):9691-7.
2006: Li Peng; Ruiwu Liu; Jan Marik; Xiaobing Wang; Yoshikazu Takada; Kit S Lam
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
Nature chemical biology 2006;2(7):381-9.
2006: Kate L Graham; Yoshikazu Takada; Barbara S Coulson
Rotavirus spike protein VP5* binds alpha2beta1 integrin on the cell surface and competes with virus for cell binding and infectivity.
The Journal of general virology 2006;87(Pt 5):1275-83.
2006: Po-Long Wu; Shao-Chen Lee; Chia-Chen Chuang; Seiji Mori; Nobuaki Akakura; Wen-guey Wu; Yoshikazu Takada
Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family.
The Journal of biological chemistry 2006;281(12):7937-45.
2006: Takehiko Tarui; Nobuaki Akakura; Mousumi Majumdar; Nicholas M Andronicos; Junichi Takagi; Andrew P Mazar; Khalil Bdeir; Alice Kuo; Serge V Yarovoi; Douglas B Cines; Yoshikazu Takada
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation.
Thrombosis and haemostasis 2006;95(3):524-34.
2005: Kate L Graham; Fiona E Fleming; Peter Halasz; Marilyn J Hewish; Hadya S Nagesha; Ian H Holmes; Yoshikazu Takada; Barbara S Coulson
Rotaviruses interact with alpha4beta7 and alpha4beta1 integrins by binding the same integrin domains as natural ligands.
The Journal of general virology 2005;86(Pt 12):3397-408.
2005: Charles Kumar Thodeti; Camilla Fröhlich; Christian Kamp Nielsen; Yoshikazu Takada; Reinhard Fässler; Reidar Albrechtsen; Ulla M Wewer
ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
FEBS letters 2005;579(25):5589-95.
2004: Kate L Graham; Weiguang Zeng; Yoshikazu Takada; David C Jackson; Barbara S Coulson
Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences.
Journal of virology 2004;78(21):11786-97.
2004: Hisako Muramatsu; Peng Zou; Hiromichi Suzuki; Yoshihiro Oda; Guo-Yun Chen; Nahoko Sakaguchi; Sadatoshi Sakuma; Nobuaki Maeda; Masaharu Noda; Yoshikazu Takada; Takashi Muramatsu
alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.
Journal of cell science 2004;117(Pt 22):5405-15.
2004: Masahito Mikawa; Henry Wang; Linlang Guo; Ruiwu Liu; Jan Marik; Yoshikazu Takada; Kit S Lam; Derick H Lau
Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells.
Molecular cancer therapeutics 2004;3(10):1329-34.
2004: Andrea Dorfleutner; Edith Hintermann; Takehiko Tarui; Yoshikazu Takada; Wolfram Ruf
Cross-talk of integrin alpha3beta1 and tissue factor in cell migration.
Molecular biology of the cell 2004;15(10):4416-25.
2004: Mousumi Majumdar; Takehiko Tarui; Biao Shi; Nobuaki Akakura; Wolfram Ruf; Yoshikazu Takada
Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1).
The Journal of biological chemistry 2004;279(36):37528-34.
2004: Hironori Takatsuki; Shinya Komatsu; Rikio Sano; Yoshikazu Takada; Tsutomu Tsuji
Adhesion of gastric carcinoma cells to peritoneum mediated by alpha3beta1 integrin (VLA-3).
Cancer research 2004;64(17):6065-70.
2004: Tetsuji Kamata; Hironobu Ambo; Wilma Puzon-McLaughlin; Kenneth Khiem Tieu; Makoto Handa; Yasuo Ikeda; Yoshikazu Takada
Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit.
The Biochemical journal 2004;378(Pt 3):1079-82.
2004: Kohei Murata; Eiji Miyoshi; Shinji Ihara; Shingo Noura; Masao Kameyama; Osamu Ishikawa; Yuichiro Doki; Terumasa Yamada; Hiroaki Ohigashi; Yo Sasaki; Masahiko Higashiyama; Takehiko Tarui; Yoshikazu Takada; Reiji Kannagi; Naoyuki Taniguchi; Shingi Imaoka
Attachment of human colon cancer cells to vascular endothelium is enhanced by N-acetylglucosaminyltransferase V.
Oncology 2004;66(6):492-501.
2003: Kate L Graham; Peter Halasz; Yan Tan; Marilyn J Hewish; Yoshikazu Takada; Erich R Mackow; Martyn K Robinson; Barbara S Coulson
Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry.
Journal of virology 2003;77(18):9969-78.
2003: Sarah L Londrigan; Kate L Graham; Yoshikazu Takada; Peter Halasz; Barbara S Coulson
Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I domain and is facilitated by the homologous beta1 subunit.
Journal of virology 2003;77(17):9486-501.
2003: Takehiko Tarui; Nicholas M Andronicos; Ralf-Peter Czekay; Andrew P Mazar; Khalil Bdeir; Graham C Parry; Alice Kuo; David J Loskutoff; Douglas B Cines; Yoshikazu Takada
Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling.
The Journal of biological chemistry 2003;278(32):29863-72.
2003: Charles Kumar Thodeti; Reidar Albrechtsen; Morten Grauslund; Meena Asmar; Christer Larsson; Yoshikazu Takada; Arthur M Mercurio; John R Couchman; Ulla M Wewer
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.
The Journal of biological chemistry 2003;278(11):9576-84.
2003: Yoshinobu Kariya; Yoshiaki Tsubota; Tomomi Hirosaki; Hiroto Mizushima; Wilma Puzon-McLaughlin; Yoshikazu Takada; Kaoru Miyazaki
Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of alpha3 chain.
Journal of cellular biochemistry 2003;88(3):506-20.
2003: N Tani; S Higashiyama; N Kawaguchi; Jun Madarame; I Ota; Y Ito; Y Ohoka; Sadao Shiosaka; Yoshikazu Takada; Nariaki Matsuura
Expression level of integrin alpha 5 on tumour cells affects the rate of metastasis to the kidney.
British journal of cancer 2003;88(2):327-33.
2002: Takehiko Tarui; Mousumi Majumdar; Lindsey A Miles; Wolfram Ruf; Yoshikazu Takada
Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin.
The Journal of biological chemistry 2002;277(37):33564-70.
2002: Jean-Pierre Lévesque; Yoshikazu Takada; Wilma Puzon-McLaughlin; Paul J Simmons
A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29).
Hybridoma and hybridomics 2002;21(4):253-60.
2002: Glen B Legge; Garrett M Morris; Michel F Sanner; Yoshikazu Takada; Arthur J Olson; Flavio Grynszpan
Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity.
Proteins 2002;48(2):151-60.
2002: Koji Eto; Clotilde Huet; Takehiko Tarui; Sergey Kupriyanov; Hai-Zhen Liu; Wilma Puzon-McLaughlin; Xi-Ping Zhang; Dean Sheppard; Eva Engvall; Yoshikazu Takada
Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions.
The Journal of biological chemistry 2002;277(20):17804-10.
2002: Hui Miao; Song Li; Ying-Li Hu; Suli Yuan; Yihua Zhao; Benjamin P C Chen; Wilma Puzon-McLaughlin; Takehiko Tarui; John Y-J Shyy; Yoshikazu Takada; Shunichi Usami; Shu Chien
Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling.
Journal of cell science 2002;115(Pt 10):2199-206.
2002: Tetsuji Kamata; Kenneth Khiem Tieu; Takehiko Tarui; Wilma Puzon-McLaughlin; Nancy Hogg; Yoshikazu Takada
The role of the CPNKEKEC sequence in the beta(2) subunit I domain in regulation of integrin alpha(L)beta(2) (LFA-1).
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2296-301.
2002: Tomoyuki Nakamura; Pilar Ruiz Lozano; Ikeda Yasuhiro; Yoshitaka Iwanaga; Aleksander Hinek; Susumu Minamisawa; Ching-Feng Cheng; Kazuhiro Kobuke; Nancy Dalton; Yoshikazu Takada; Kei Tashiro; John Ross Jr; Tasuku Honjo; Kenneth R Chien
Fibulin-5/DANCE is essential for elastogenesis in vivo.
Nature 2002;415(6868):171-5.
2002: Hironori Kikkawa; Masako Kaihou; Natsuko Horaguchi; Takayuki Uchida; Hidetoshi Imafuku; Ayano Takiguchi; Yukako Yamazaki; Chieko Koike; Ryoko Kuruto; Takeharu Kakiuchi; Hideo Tsukada; Yoshikazu Takada; Nariaki Matsuura; Naoto Oku
Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses.
Clinical & experimental metastasis 2002;19(8):717-25.
2001: T Kamata; Yoshikazu Takada
Platelet integrin alphaIIbbeta3-ligand interactions: what can we learn from the structure?
International journal of hematology 2001;74(4):382-9.
2001: Tetsuji Kamata; Kenneth Khiem Tieu; A Irie; T A Springer; Yoshikazu Takada
Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model.
The Journal of biological chemistry 2001;276(47):44275-83.
2001: Takehiko Tarui; Lindsey A Miles; Yoshikazu Takada
Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.
The Journal of biological chemistry 2001;276(43):39562-8.
2001: Gabriele Weitz-Schmidt; Karl Welzenbach; Volker Brinkmann; T Kamata; Joerg Kallen; Christian Bruns; Sylvain Cottens; Yoshikazu Takada; Ulrich Hommel
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.
Nature medicine 2001;7(6):687-92.
2001: Takehiko Tarui; Andrew P Mazar; Douglas B Cines; Yoshikazu Takada
Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.
The Journal of biological chemistry 2001;276(6):3983-90.
2001: N Tani; K Matsumoto; I Ota; Shigetaka Yoshida; Yoshikazu Takada; Sadao Shiosaka; N Matsuura
Effects of fibronectin cleaved by neuropsin on cell adhesion and migration.
Neuroscience research 2001;39(2):247-51.
2001: Kathy Triantafilou; Yoshikazu Takada; Martha Triantafilou
Mechanisms of integrin-mediated virus attachment and internalization process.
Critical reviews in immunology 2001;21(4):311-22.
2000: Koji Eto; Wilma Puzon-McLaughlin; Dean Sheppard; A Sehara-Fujisawa; Xi-Ping Zhang; Yoshikazu Takada
RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction.
The Journal of biological chemistry 2000;275(45):34922-30.
2000: Jonathan M. G. Higgins; Manuela Cernadas; K Tan; A Irie; J Wang; Yoshikazu Takada; Michael B Brenner
The role of alpha and beta chains in ligand recognition by beta 7 integrins.
The Journal of biological chemistry 2000;275(33):25652-64.
2000: Jonathan D Humphries; Janet Askari; X P Zhang; Yoshikazu Takada; Martin J Humphries; Paul Mould
Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit.
The Journal of biological chemistry 2000;275(27):20337-45.
2000: Kathy Triantafilou; Martha Triantafilou; Yoshikazu Takada; Nelson Fernandez
Human parechovirus 1 utilizes integrins alphavbeta3 and alphavbeta1 as receptors.
Journal of virology 2000;74(13):5856-62.
2000: K Yokoyama; H P Erickson; Y Ikeda; Yoshikazu Takada
Identification of amino acid sequences in fibrinogen gamma -chain and tenascin C C-terminal domains critical for binding to integrin alpha vbeta 3.
The Journal of biological chemistry 2000;275(22):16891-8.
2000: Martha Triantafilou; Kathy Triantafilou; KM Wilson; Yoshikazu Takada; Nelson Fernandez
High affinity interactions of Coxsackievirus A9 with integrin alphavbeta3 (CD51/61) require the CYDMKTTC sequence of beta3, but do not require the RGD sequence of the CAV-9 VP1 protein.
Human immunology 2000;61(5):453-9.
2000: Santiago Cal; José M P Freije; J M López; Yoshikazu Takada; Carlos López-Otín
ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alphavbeta3 integrin through an RGD-independent mechanism.
Molecular biology of the cell 2000;11(4):1457-69.
2000: Wilma Puzon-McLaughlin; Tetsuji Kamata; Yoshikazu Takada
Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).
The Journal of biological chemistry 2000;275(11):7795-802.
2000: Marilyn J Hewish; Yoshikazu Takada; Barbara S Coulson
Integrins alpha2beta1 and alpha4beta1 can mediate SA11 rotavirus attachment and entry into cells.
Journal of virology 2000;74(1):228-36.
1999: Tetsuji Kamata; Robert C Liddington; Yoshikazu Takada
Interaction between collagen and the alpha(2) I-domain of integrin alpha(2)beta(1). Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region.
The Journal of biological chemistry 1999;274(45):32108-11.
1999: Xi-Ping Zhang; Wilma Puzon-McLaughlin; A Irie; N Kovach; N L Prokopishyn; Suzanne Laferté; K Takeuchi; T Tsuji; Yoshikazu Takada
Alpha 3 beta 1 adhesion to laminin-5 and invasin: critical and differential role of integrin residues clustered at the boundary between alpha 3 N-terminal repeats 2 and 3.
Biochemistry 1999;38(43):14424-31.
1999: Martha Triantafilou; Kathy Triantafilou; KM Wilson; Yoshikazu Takada; Nelson Fernandez; Glyn Stanway
Involvement of beta2-microglobulin and integrin alphavbeta3 molecules in the coxsackievirus A9 infectious cycle.
The Journal of general virology 1999;80 ( Pt 10)():2591-600.
1999: K Yokoyama; Xi-Ping Zhang; Leonid Medved; Yoshikazu Takada
Specific binding of integrin alpha v beta 3 to the fibrinogen gamma and alpha E chain C-terminal domains.
Biochemistry 1999;38(18):5872-7.
1999: J E Meredith; William B Kiosses; Yoshikazu Takada; Martin A Schwartz
Mutational analysis of cell cycle inhibition by integrin beta1C.
The Journal of biological chemistry 1999;274(12):8111-6.
1999: N L Prokopishyn; Wilma Puzon-McLaughlin; Yoshikazu Takada; Suzanne Laferté
Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes.
Journal of cellular biochemistry 1999;72(2):189-209.
1998: Paul D Lampe; BP Nguyen; Susana G Gil; M Usui; John E Olerud; Yoshikazu Takada; William G Carter
Cellular interaction of integrin alpha3beta1 with laminin 5 promotes gap junctional communication.
The Journal of cell biology 1998;143(6):1735-47.
1998: Hironobu Ambo; T Kamata; Makoto Handa; M Taki; M Kuwajima; Yohko Kawai; Atsushi Oda; Mitsuru Murata; Yoshikazu Takada; Kiyoaki Watanabe; Yasuo Ikeda
Three novel integrin beta3 subunit missense mutations (H280P, C560F, and G579S) in thrombasthenia, including one (H280P) prevalent in Japanese patients.
Biochemical and biophysical research communications 1998;251(3):763-8.
1998: Hironobu Ambo; T Kamata; Makoto Handa; Yohko Kawai; Atsushi Oda; Mitsuru Murata; Yoshikazu Takada; Yasuo Ikeda
Novel point mutations in the alphaIIb subunit (Phe289-->Ser, Glu324-->Lys and Gln747-->Pro) causing thrombasthenic phenotypes in four Japanese patients.
British journal of haematology 1998;102(3):829-40.
1998: Takuhiko Akatsu; Katsuhiro Ono; Takehiko Murakami; Y Katayama; M Nishikawa; S Wada; Michiko Yamamoto; Nobuo Kugai; N Matsuura; Yoshikazu Takada; Naokazu Nagata
Chinese hamster ovary cells expressing alpha4beta1 integrin stimulate osteoclast formation in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(8):1251-9.
1998: J Tsuchida; S Ueki; Yoshikazu Takada; Yuji Saito; J Takagi
The 'ligand-induced conformational change' of alpha 5 beta 1 integrin. Relocation of alpha 5 subunit to uncover the beta 1 stalk region.
Journal of cell science 1998;111 ( Pt 12)():1759-66.
1998: Paul Mould; Alistair Garratt; W Puzon-McLaughlin; Yoshikazu Takada; Martin J Humphries
Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.
The Biochemical journal 1998;331 ( Pt 3)():821-8.
1998: Xi-Ping Zhang; Tetsuji Kamata; K Yokoyama; Wilma Puzon-McLaughlin; Yoshikazu Takada
Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.
The Journal of biological chemistry 1998;273(13):7345-50.
1997: SL King; T Kamata; JA Cunningham; Jonas Emsley; Robert C Liddington; Yoshikazu Takada; Jeffrey M Bergelson
Echovirus 1 interaction with the human very late antigen-2 (integrin alpha2beta1) I domain. Identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site.
The Journal of biological chemistry 1997;272(45):28518-22.
1997: Yoshikazu Takada; Tetsuji Kamata; A Irie; Wilma Puzon-McLaughlin; Xi-Ping Zhang
Structural basis of integrin-mediated signal transduction.
Matrix biology : journal of the International Society for Matrix Biology 1997;16(4):143-51.
1997: J Takagi; Tetsuji Kamata; J Meredith; Wilma Puzon-McLaughlin; Yoshikazu Takada
Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit.
The Journal of biological chemistry 1997;272(32):19794-800.
1997: Paul Mould; Janet Askari; S i Aota; K M Yamada; A Irie; Yoshikazu Takada; H J Mardon; Martin J Humphries
Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit.
The Journal of biological chemistry 1997;272(28):17283-92.
1997: A Irie; Tetsuji Kamata; Yoshikazu Takada
Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7198-203.
1997: A Irie; T Kamata; Yoshikazu Takada
[Molecular mechanisms of integrin-ligand interaction].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1679-86.
1997: J Takagi; Toshiaki Isobe; Yoshikazu Takada; Y Saito
Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope.
Journal of biochemistry 1997;121(5):914-21.
1997: Toshiaki Isobe; T Hisaoka; A Shimizu; M Okuno; S Aimoto; Yoshikazu Takada; Yuji Saito; J Takagi
Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin.
The Journal of biological chemistry 1997;272(13):8447-53.
1996: Randall J Faull; J Wang; David Leavesley; W Puzon; Graeme R Russ; D Vestweber; Yoshikazu Takada
A novel activating anti-beta1 integrin monoclonal antibody binds to the cysteine-rich repeats in the beta1 chain.
The Journal of biological chemistry 1996;271(41):25099-106.
1996: A Irie; T Kamata; Yoshikazu Takada
[Integrin family].
Rinsho byori. The Japanese journal of clinical pathology 1996;Suppl 102():16-23.
1996: Wilma Puzon-McLaughlin; Yoshikazu Takada
Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.
The Journal of biological chemistry 1996;271(34):20438-43.
1996: Tetsuji Kamata; A Irie; M Tokuhira; Yoshikazu Takada
Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).
The Journal of biological chemistry 1996;271(31):18610-5.
1996: Wilma Puzon-McLaughlin; T A Yednock; Yoshikazu Takada
Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain.
The Journal of biological chemistry 1996;271(28):16580-5.
1996: JL Sechler; Yoshikazu Takada; Jean E Schwarzbauer
Altered rate of fibronectin matrix assembly by deletion of the first type III repeats.
The Journal of cell biology 1996;134(2):573-83.
1996: Shuang Huang; Tetsuji Kamata; Yoshikazu Takada; Z M Ruggeri; Glen R Nemerow
Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells.
Journal of virology 1996;70(7):4502-8.
1996: Alfonso Luque; M Gómez; W Puzon; Yoshikazu Takada; Francisco Sánchez-Madrid; Carlos Cabañas
Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain.
The Journal of biological chemistry 1996;271(19):11067-75.
1996: N Matsuura; Wilma Puzon-McLaughlin; A Irie; Y Morikawa; K Kakudo; Yoshikazu Takada
Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells.
The American journal of pathology 1996;148(1):55-61.
1995: A Irie; Tetsuji Kamata; Wilma Puzon-McLaughlin; Yoshikazu Takada
Critical amino acid residues for ligand binding are clustered in a predicted beta-turn of the third N-terminal repeat in the integrin alpha 4 and alpha 5 subunits.
The EMBO journal 1995;14(22):5550-6.
1995: J Meredith; Yoshikazu Takada; Mara Fornaro; Lucia R Languino; Martin A Schwartz
Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C.
Science (New York, N.Y.) 1995;269(5230):1570-2.
1995: N Matsuura; E Tashita; J Yamamura; Y Kagawa; Yoshikazu Takada
[Analysis of the mechanism of tumor metastasis by the transfection of integrin cDNA].
Nihon rinsho. Japanese journal of clinical medicine 1995;53(7):1643-7.
1995: N Matsuura; Yoshikazu Takada
[Subclassification, molecular structure, function and ligand in integrin superfamily].
Nihon rinsho. Japanese journal of clinical medicine 1995;53(7):1623-30.
1995: Tetsuji Kamata; R Wright; Yoshikazu Takada
Critical threonine and aspartic acid residues within the I domains of beta 2 integrins for interactions with intercellular adhesion molecule 1 (ICAM-1) and C3bi.
The Journal of biological chemistry 1995;270(21):12531-5.
1995: Tetsuji Kamata; W Puzon; Yoshikazu Takada
Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)
The Biochemical journal 1995;305 ( Pt 3)():945-51.
1994: Tetsuji Kamata; Yoshikazu Takada
Direct binding of collagen to the I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner.
The Journal of biological chemistry 1994;269(42):26006-10.
1994: Tetsuji Kamata; W Puzon; Yoshikazu Takada
Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)
The Journal of biological chemistry 1994;269(13):9659-63.
1993: Yoshikazu Takada; W Puzon
Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.
The Journal of biological chemistry 1993;268(23):17597-601.
1993: Jari Ylänne; Y Chen; T E O'Toole; Joseph C Loftus; Yoshikazu Takada; Mark H Ginsberg
Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions.
The Journal of cell biology 1993;122(1):223-33.
1993: J B Weitzman; R Pasqualini; Yoshikazu Takada; Martin Helmer
The function and distinctive regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation.
The Journal of biological chemistry 1993;268(12):8651-7.
1993: B E Symington; Yoshikazu Takada; William G Carter
Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.
The Journal of cell biology 1993;120(2):523-35.
1992: S Kawaguchi; K Kikuchi; S Ishii; Yoshikazu Takada; S Kobayashi; T Uede
VLA-4 molecules on tumor cells initiate an adhesive interaction with VCAM-1 molecules on endothelial cell surface.
Japanese journal of cancer research : Gann 1992;83(12):1304-16.
1992: Yoshikazu Takada; Jari Ylänne; D Mandelman; W Puzon; Mark H Ginsberg
A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques.
The Journal of cell biology 1992;119(4):913-21.
1991: H Neuhaus; M C Hu; Martin Helmer; Yoshikazu Takada; Bernhard Holzmann; Irving L Weissman
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
The Journal of cell biology 1991;115(4):1149-58.
1991: Yoshikazu Takada; E Murphy; P Pil; C Chen; Mark H Ginsberg; Martin Helmer
Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen.
The Journal of cell biology 1991;115(1):257-66.
1991: Bosco M C Chan; N Matsuura; Yoshikazu Takada; B R Zetter; Martin Helmer
In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells.
Science (New York, N.Y.) 1991;251(5001):1600-2.
1990: Martin Helmer; M J Elices; Bosco M C Chan; B Zetter; N Matsuura; Yoshikazu Takada
Multiple ligand binding functions for VLA-2 (alpha 2 beta 1) and VLA-3 (alpha 3 beta 1) in the integrin family.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists 1990;32(3):229-38.
1990: P E Purdue; Yoshikazu Takada; Christopher J Danpure
Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.
The Journal of cell biology 1990;111(6 Pt 1):2341-51.
1990: Yoshikazu Takada; N Kaneko; H Esumi; P E Purdue; Christopher J Danpure
Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon.
The Biochemical journal 1990;268(2):517-20.
1990: Martin Helmer; M J Elices; C Parker; Yoshikazu Takada
Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions.
Immunological reviews 1990;114():45-65.
1990: M J Elices; L Osborn; Yoshikazu Takada; C Crouse; S Luhowskyj; Martin Helmer; Roy R Lobb
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.
Cell 1990;60(4):577-84.
1989: Yoshikazu Takada; Martin Helmer
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.
The Journal of cell biology 1989;109(1):397-407.
1989: Yoshikazu Takada; M J Elices; C Crouse; Martin Helmer
The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
The EMBO journal 1989;8(5):1361-8.
1988: Yoshikazu Takada; E A Wayner; William G Carter; Martin Helmer
Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimers.
Journal of cellular biochemistry 1988;37(4):385-93.
1988: Martin Helmer; C Crouse; Yoshikazu Takada; A Sonnenberg
Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.
The Journal of biological chemistry 1988;263(16):7660-5.
1987: Martin Helmer; C Huang; Yoshikazu Takada; L Schwarz; J L Strominger; M L Clabby
Characterization of the cell surface heterodimer VLA-4 and related peptides.
The Journal of biological chemistry 1987;262(24):11478-85.
1987: Yoshikazu Takada; J L Strominger; Martin Helmer
The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3239-43.
1987: Yoshikazu Takada; C Huang; Martin Helmer
Fibronectin receptor structures in the VLA family of heterodimers.
Nature 1987;326(6113):607-9.
1982: Yoshikazu Takada; T Noguchi
The evolution of peroxisomal and mitochondrial alanine: glyoxylate aminotransferase 1 in mammalian liver.
Biochemical and biophysical research communications 1982;108(1):153-7.
1982: Yoshikazu Takada; T Noguchi
Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes in different mammalian species.
Comparative biochemistry and physiology. B, Comparative biochemistry 1982;72(4):597-604.
1978: T Noguchi; E Okuno; Yoshikazu Takada; Y Minatogawa; K Okai; R Kido
Characteristics of hepatic alanine-glyoxylate aminotransferase in different mammalian species.
The Biochemical journal 1978;169(1):113-22.
1977: T Noguchi; Yoshikazu Takada; R Kido
Characteristics of hepatic serine-pyruvate aminotransferase in different mammalian species.
The Biochemical journal 1977;161(3):609-14.